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Development Of Informative Priors In Microarray Studies, Kassandra M. Fronczyk Jul 2007

Development Of Informative Priors In Microarray Studies, Kassandra M. Fronczyk

Theses and Dissertations

Microarrays measure the abundance of DNA transcripts for thousands of gene sequences, simultaneously facilitating genomic comparisons across tissue types or disease status. These experiments are used to understand fundamental aspects of growth and development and to explore the underlying genetic causes of many diseases. The data from most microarray studies are found in open-access online databases. Bayesian models are ideal for the analysis of microarray data because of their ability to integrate prior information; however, most current Bayesian analyses use empirical or flat priors. We present a Perl script to build an informative prior by mining online databases for similar …

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Planning Gone Hog Wild: Mega-Hog Farm In A Mountain West County, Jeffrey Melvin Sanders Jul 2007

Planning Gone Hog Wild: Mega-Hog Farm In A Mountain West County, Jeffrey Melvin Sanders

Theses and Dissertations

Lacking the natural amenities “New West" counties, some rural communities have attempted to attract land use activities that are normally seen as undesirable. One example of these undesirable industries is the hog concentrated animal feeding operation, or CAFO. While a number of studies have explored the socio-economic and environmental aspects of hog farms, few studies have focused on the planning process and evaluated its effectiveness in dealing with the threats and challenges that a CAFO poses. This qualitative study used interviews, observations, public meeting minutes, and other written sources of data to evaluate whether or not a rural, western community, …

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On Stability And Evolution Of Solutions In General Relativity, Stephen M. Taylor Jul 2007

On Stability And Evolution Of Solutions In General Relativity, Stephen M. Taylor

Theses and Dissertations

This thesis is concerned with several problems in general relativity and low energy string theory that are pertinent to the time evolution of the gravitational field. We present a formulation of the Einstein field equations in terms of variational techniques borrowed from geometric analysis. These equations yield the evolution equations for the Cauchy problems of both general relativity and low energy string theory. We then proceed to investigate the evolutionary linear stability of Schwarzschild-like solutions in higher dimensional relativity called black strings. These objects are determined to be linearly unstable. This motivates a further stability analysis of the charged p-brane …

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James E. Talmage And The Nature Of The Godhead: The Gradual Unfolding Of Latter-Day Saint Theology, Brian William Ricks Jul 2007

James E. Talmage And The Nature Of The Godhead: The Gradual Unfolding Of Latter-Day Saint Theology, Brian William Ricks

Theses and Dissertations

Since the beginning of Christianity, the debates over the nature of God have been frequent and ardent. Augustine, John Calvin, and John Wesley, with others, supplemented the generally accepted view of the Godhead as established at the Council of Nicaea in 325 A.D. Correctly understanding the Father, the Son, and the Holy Ghost is one of the most critical aspects of religious worship. The Savior said, "And this is life eternal, that they may come to know thee the only true God, and Jesus Christ, whom thou hast sent" (John 17:3). Joseph Smith, the first Latter-day Saint Prophet, taught a …

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The Effect Of Video Self-Modeling On The Compliance Rates Of High School Students With Developmental Disabilities, Jacob Ammon Aukai Figueira Jul 2007

The Effect Of Video Self-Modeling On The Compliance Rates Of High School Students With Developmental Disabilities, Jacob Ammon Aukai Figueira

Theses and Dissertations

People with developmental disabilities must develop the ability to maintain socially acceptable behavior in order to become contributing, accepted members of society at large. Research indicates that compliance, or following directions, is a keystone behavior, which, if learned, may significantly decrease the occurrence of behavior difficulties in students. Many studies of individuals with disabilities have shown a dramatic increase across a wide range of academic and social skills using video self-modeling (VSM), a technique in which students watch edited videos of themselves performing skills correctly or at high rates. Despite the importance of compliance for individuals with disabilities and the …

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Holmes, Alice, And Ezeulu: Western Rationality In The Context Of British Colonialism And Western Modernity, Andrew B. Schultz Jul 2007

Holmes, Alice, And Ezeulu: Western Rationality In The Context Of British Colonialism And Western Modernity, Andrew B. Schultz

Theses and Dissertations

This thesis examines Western rationality, contextualizing that subject in British colonialism and Western modernity. Using Scott Lash's description of academic characterizations of modernity, I explore the “high" modernity of the social sciences represented in the books Alice's Adventures in Wonderland by Lewis Carroll and The Hound of the Baskervilles by Arthur Conan Doyle. I then explore the cultural studies critique of that characterization of modernity in the book Arrow of God by Chinua Achebe. Using the theory of Jean Francois Lyotard, Martin Heidegger, and Theodor Adorno, I look at Western rationality through its manifestation in British colonialism. I argue that …

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Factors Contributing To The Shortage Of Speech-Language Pathologists In Utah Schools, Stephanie Harris Jul 2007

Factors Contributing To The Shortage Of Speech-Language Pathologists In Utah Schools, Stephanie Harris

Theses and Dissertations

This study examined factors contributing to Utah's critical shortage of school-based speech-language pathologists. Specifically, this study focused on the following three constructs: (a) stress levels among professionals currently in the field, (b) attrition and the reasons professionals leave their positions, and (c) factors at the university level. Stress among Utah's speech-language pathologists was assessed using the Speech-Language Pathologist Stress Inventory (Fimian, Lieberman, & Fasteneau, 1991). Of the 230 potential participants, 97 completed and returned questionnaires. Results indicated that Utah's school-based speech-language pathologists experience less overall stress than a normative sample of speech-language pathologists throughout the United States; however, Utah's professionals …

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Elliptical Rolling Link Toggle Mechanisms For Passive Force Closures With Self-Adjustment, Jacob Ross Montierth Jul 2007

Elliptical Rolling Link Toggle Mechanisms For Passive Force Closures With Self-Adjustment, Jacob Ross Montierth

Theses and Dissertations

This thesis presents elliptical rolling contact joints as an alternative to circular rolling contact and conventional revolute joints where high quality force transmission "low friction and backlash" with variable output are desired. Parameters specific to the joint and its position are developed in terms of relative link angles and elliptical surface geometry. These parameters are used to generate the basic forward kinematics for elliptical rolling link toggle mechanisms with oscillatory motion and high mechanical advantage. As large compressive loads are characteristic of such mechanisms, stress conditions are identified and principles for joint stability with variable, precision outputs are discussed. Finally, …

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A Family Literacy Curriculum For Community Esl Courses, George William Clair Bailey Jul 2007

A Family Literacy Curriculum For Community Esl Courses, George William Clair Bailey

Theses and Dissertations

This project describes the piloting of a family literacy curriculum developed for use in a community ESL course. The purpose of this curriculum was to teach family-literacy-oriented English to students in the community ESL courses that are part of Brigham Young University's TESOL Teacher Training Course (TTTC) held at the University Parkway Center on BYU's campus. Students in BYU's TESOL Graduate Certificate program are required to complete a one-semester teaching practicum in the TTTC program. This program regularly offers English courses that enroll approximately 100 ESL students from the local community who are non-native speakers of English. These ESL students …

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Buckling-Restrained Braced Frame Connection Design And Testing, Bradly B. Coy Jul 2007

Buckling-Restrained Braced Frame Connection Design And Testing, Bradly B. Coy

Theses and Dissertations

As typically designed, the beam-column-brace connections of buckling-restrained braced steel frames have undesirable failure modes that compromise the integrity and performance of the frames and are costly to repair. To decrease the time and resources needed to repair the frames following an earthquake, a new connection design was developed that attempts to confine yielding to replaceable frame components. The design incorporates a gap in the beam beyond the edge of the beam-gusset weld that acts as a hinge and reduces moment forces transferred to the connection; it is bridged by splice plates that are bolted to the beam top flanges. …

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Teacher Perceptions Of The Social Validity Of The Peaceable Schools Model, Rachelle Marie Pieper Jul 2007

Teacher Perceptions Of The Social Validity Of The Peaceable Schools Model, Rachelle Marie Pieper

Theses and Dissertations

The purpose of this study was to evaluate the social validity of the Peaceable Schools model, which includes positive behavior support and social skills training. Data were collected through subjective evaluation using an open-ended survey given to teachers at two secondary schools. Results show that teachers perceived evidence of social validity in the areas of social significance, comprehensiveness, relevance, treatment integrity, and social acceptability. While weaknesses were also expressed in the areas of social acceptability, feasibility, and practicality, teachers perceived overall improvement in students' social skills and saw more strengths than weaknesses. Outcomes suggest that the Peaceable Schools model has …

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Amp-Activated Protein Kinase Kinase Activity And Phosphorylation Of Amp-Activated Protein Kinase In Contracting Muscle Of Sedentary And Endurance Trained Rats, Denise Hurst Jul 2007

Amp-Activated Protein Kinase Kinase Activity And Phosphorylation Of Amp-Activated Protein Kinase In Contracting Muscle Of Sedentary And Endurance Trained Rats, Denise Hurst

Theses and Dissertations

This study was designed to examine activity of AMP-activated protein kinase kinase (AMPKK) and AMP-activated protein kinase (AMPK) in muscles from control (C) and endurance trained (T) rats. Rats were trained 5 days/wk, 2 hr/d for 8 wks at a final intensity of 32 m/min up a 15% grade with 30 second sprints at 52 m/min every 10 min. Gastrocnemius muscles were stimulated in situ in T and C rats for 5 min at frequencies of 0.4/sec and 1/sec. Gastrocnemius LKB1 protein, a putative component of the AMPKK complex (LKB1, STRAD, and MO25), increased approximately 2-fold in response to training. …

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Loading Rate Effects On Axial Pile Capacity In Clays, Michael Paul Garner Jul 2007

Loading Rate Effects On Axial Pile Capacity In Clays, Michael Paul Garner

Theses and Dissertations

In order to design more efficient and reliable structures, axial load tests are performed on foundation piles. Traditionally, static tests with an average duration of approximately twenty-four hours have been performed on test piles to obtain their axial capacity. These static tests require multiple piles used as anchors in addition to the test pile. Static tests are both expensive and time consuming. An alternative to static testing is dynamic testing which requires sophisticated interpretation, can damage the pile and may not produce accurate results. There is a relatively new testing method called the Statnamic Testing Method which tests foundation piles …

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Soft Surface Roll Mechanics Parameters For Light Vehicle Rollover Accident Reconstruction, Kevin Claude Henry Jul 2007

Soft Surface Roll Mechanics Parameters For Light Vehicle Rollover Accident Reconstruction, Kevin Claude Henry

Theses and Dissertations

Light vehicle rollover accidents on soft surfaces can be modeled assuming constant drag with linear motion equations and other engineering principles. The concept of using segment average results to evaluate roll mechanics parameters throughout a roll sequence, and specifically, segment duration to evaluate vehicle trajectory between ground impacts is developed. The trajectory model is presented, explained and compared to values obtained by analyzing digital video of rollover crash tests. Detailed film analysis procedures are developed to obtain data from rollover crash tests that are not otherwise documented. Elevation of the center of gravity of vehicles is obtained where instrumentation does …

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An Examination Of The Relationship Between Family Leisure Satisfaction And Satisfaction With Family Life, Joel Ryan Agate Jul 2007

An Examination Of The Relationship Between Family Leisure Satisfaction And Satisfaction With Family Life, Joel Ryan Agate

Theses and Dissertations

The purpose of this study was to examine the relationship between family leisure satisfaction and satisfaction with family life. Zabriskie's Family Leisure Activity Profile (FLAP) was used to measure core, balance, and total family leisure satisfaction. The Satisfaction With Family Life Scale (SWFL) an adaptation of Diener, Emmons, Larsen, and Griffin's satisfaction With Life Scale (SWLS), done by Zabriskie and McCormick, was used to measure satisfaction with family life. The sample consisted of 898 parent and youth pairs from throughout the United States. Results indicated that there was a relationship between all family leisure satisfaction variables and satisfaction with family …

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Evidence Supporting The Validity Of Inferences Required By The Intended Uses Of The Technology Integration Confidence Scale, Jeremy Michael Browne Jul 2007

Evidence Supporting The Validity Of Inferences Required By The Intended Uses Of The Technology Integration Confidence Scale, Jeremy Michael Browne

Theses and Dissertations

Many teacher preparation programs provide opportunities for their preservice educators to gain the requisite technology integration skills and knowledge. However, they often ignore the dispositions that affect whether a teacher will actually use technology in the classroom. In an effort to address this oversight, the McKay School of Education at Brigham Young University developed the Technology Integration Confidence Scale (TICS). It was hoped the TICS could be used to (a) establish a baseline preservice teacher profile, (b) monitor the effects of curricular adjustments, (c) identify preservice teachers in most need of intervention, and (d) predict in-practice behavior. Although a pilot …

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Reliability Of Pre-Service Teachers Coding Of Teaching Videos Using Video-Annotation Tools, Brigham R. Dye Jul 2007

Reliability Of Pre-Service Teachers Coding Of Teaching Videos Using Video-Annotation Tools, Brigham R. Dye

Theses and Dissertations

Teacher education programs that aspire to helping pre-service teachers develop expertise must help students engage in deliberate practice along dimensions of teaching expertise. However, field teaching experiences often lack the quantity and quality of feedback that is needed to help students engage in meaningful teaching practice. The limited availability of supervising teachers makes it difficult to personally observe and evaluate each student teacher's field teaching performances. Furthermore, when a supervising teacher debriefs such an observation, the supervising teacher and student may struggle to communicate meaningfully about the teaching performance. This is because the student teacher and supervisor often have very …

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Development Of Chemomechanical Functionalization And Nanografting On Silicon Surfaces, Michael Vernon Lee Jul 2007

Development Of Chemomechanical Functionalization And Nanografting On Silicon Surfaces, Michael Vernon Lee

Theses and Dissertations

Progress in chemomechanical functionalization was made by investigating the binding of molecules and surface coverage on the silicon surface, demonstrating functionalization of silicon with gases by chemomechanical means, analyzing atomic force microscopy probe tip wear in atomic force microscopy (AFM) chemomechanical nanografting, combining chemomechanical functionalization and nanografting to pattern silicon with an atomic force microscope, and extending chemomechanical nanografting to silicon dioxide. Molecular mechanics of alkenes and alkynes bound to Si(001)-2x1 as a model of chemomechanically functionalized surfaces indicated that complete coverage is energetically favorable and becomes more favorable for longer chain species. Scribing a silicon surface in the presence …

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And There Were Green Tiles On The Ceiling, Jean Catherine Richardson Jul 2007

And There Were Green Tiles On The Ceiling, Jean Catherine Richardson

Theses and Dissertations

In this document I shall explain my art process, and reflecting on my work, will explore the themes and emotions that evolved. I shall accompany the images of my MFA exhibition with personal poetic vignettes. These vignettes are memories and thoughts that surfaced both while making the art and while viewing the final exhibition. While the primary experience is looking at and being with my art, I hope these anecdotes and stories give some insight into my motivations and actions as an artist. In these stories I shall use my own voice; I am Scottish and will tend to use …

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Dynamic Testing Of A Full-Scale Pile Cap With Dense Silty Sand Backfill, Todd J. Valentine Jul 2007

Dynamic Testing Of A Full-Scale Pile Cap With Dense Silty Sand Backfill, Todd J. Valentine

Theses and Dissertations

Full-scale dynamic lateral load tests were performed on a pile cap with a dense silty sand backfill condition. Two hydraulic load actuators connected a test pile cap with a reaction cap. The load actuators incrementally loaded the test cap up to 50 mm of displacement. After each load increment, the displacement was held constant while an eccentric mass shaker induced dynamic loads under a ramping sequence from 1 Hz to 10 Hz. A baseline response was developed under a no backfill condition. Passive soil pressure was measured using pressure cells and tactile sensors. It was concluded that the presence of …

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Navajo Baskets And The American Indian Voice: Searching For The Contemporary Native American In The Trading Post, The Natural History Museum, And The Fine Art Museum, Laura Paulsen Howe Jul 2007

Navajo Baskets And The American Indian Voice: Searching For The Contemporary Native American In The Trading Post, The Natural History Museum, And The Fine Art Museum, Laura Paulsen Howe

Theses and Dissertations

This thesis examines the display of Navajo baskets and examines some of the possible meanings Navajo baskets can reveal. Acknowledging that the meaning of a work of art changes when it is placed in different environments, the thesis explores what meanings are revealed and what meanings are concealed in basket displays in three venues: the trading post, the natural history museum, and the fine art museum. The study concludes that the fine art museum has the most potential to foster a dialogue about the contemporary Navajo, whose identity is a product of continuity and change. Chapter one discusses the basket's …

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Seismic And Well Log Attribute Analysis Of The Jurassic Entrada/Curtis Interval Within The North Hill Creek 3d Seismic Survey, Uinta Basin, Utah, A Case History, Ryan J. Oneal Jul 2007

Seismic And Well Log Attribute Analysis Of The Jurassic Entrada/Curtis Interval Within The North Hill Creek 3d Seismic Survey, Uinta Basin, Utah, A Case History, Ryan J. Oneal

Theses and Dissertations

3D seismic attribute analysis of the Jurassic Entrada/Curtis interval within the North Hill Creek (NHC) survey has been useful in delineating reservoir quality eolian-influenced dune complexes. Amplitude, average reflection strength and spectral decomposition appear to be most useful in locating reservoir quality dune complexes, outlining their geometry and possibly displaying lateral changes in thickness. Cross sectional views displaying toplap features likely indicate an unconformity between Entrada clinoforms below and Curtis planar beds above. This relationship may aid the explorationist in discovering this important seismic interval. Seismic and well log attribute values were cross plotted and have revealed associations between these …

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La Guérison Par Le Récit Chez Gabrielle Roy, Kathleen L. Byrne Jul 2007

La Guérison Par Le Récit Chez Gabrielle Roy, Kathleen L. Byrne

Theses and Dissertations

The therapeutic nature of Gabrielle Roy's works enables an Aristotelian catharsis to take place for her audience. As her readers plunge into their individual past, they can have an awakening. Upon realizing that the characters in Roy's literary creation hold to a specific definition of elusive happiness and after discovering that they also are plagued by a fixation to some type of Freudian trauma, the readers can recognize similar behavior in themselves. Though likely they were unconscious of their ongoing distress before, now it becomes clear that their tendency to displace themselves in pursuit of a utopian existence is perpetual …

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The Young Women Resource Room: An Implementation Of A Dvd-Based Training Station Instructional Program, Scott R. Hamblin Jul 2007

The Young Women Resource Room: An Implementation Of A Dvd-Based Training Station Instructional Program, Scott R. Hamblin

Theses and Dissertations

A review of the development and implementation of a DVD-based kiosk for the Young Women (YW) organization of The Church of Jesus Christ of Latter-Day Saints. The Young Women desired to implement a public kiosk to display several multimedia-based presentations relating to the YW program. This paper describes the development, usability evaluation, and implementation of the kiosk. Recommendations for improvements and further enhancements are included. The project was successfully developed and implemented to the satisfaction of the Young Women General Presidency.

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Cloning And Characterization Of The Salt Overly Sensitive 1 (Sos1) Gene In Chenopodium Quinoa Willd., Taylor Brian Turner Jul 2007

Cloning And Characterization Of The Salt Overly Sensitive 1 (Sos1) Gene In Chenopodium Quinoa Willd., Taylor Brian Turner

Theses and Dissertations

Salt tolerance is a commercially important trait that affects plant species around the globe. Cellular response to saline environments is a well studied but complex system that is far from being completely understood. The SALT OVERLY SENSITIVE 1 (SOS1) gene is a critical component of salt tolerance in many species, encoding a plasma membrane Na+/H+ antiporter that plays an important role in germination and growth in saline environments. Here we report a preliminary investigation of salt tolerance in quinoa (Chenopodium quinoa Willd.). Quinoa is a halophytic grain crop of the Chenopodiaceae family with impressive nutritional content and an increasing world-wide …

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Phlebitis Rates In Trauma Patients: Peripheral Intravenous Catheters Started In Or Outside The Emergency Department, Ligia J. Zarate Jul 2007

Phlebitis Rates In Trauma Patients: Peripheral Intravenous Catheters Started In Or Outside The Emergency Department, Ligia J. Zarate

Theses and Dissertations

Ligia J. Zarate College of Nursing Master of Science Peripheral catheter-related phlebitis is the inflammation of a superficial vein that can lead to infection or thrombus formation if untreated. About 150 million peripheral intravenous catheters (PIVC) are inserted in the United States each year with phlebitis rates reported between 5% and 70%. Many PIVCs are started on trauma patients, but the rate of phlebitis in trauma patients whether the PIVC is started outside the emergency department (ED) or inside the ED is unknown. Therefore, the purpose of this pilot study was to determine phlebitis rates in trauma patients when PIVC's …

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Palmitoylation And Oxidation Of The Cysteine Rich Region Of Snap-25 And Their Effects On Protein Interactions, Derek Luberli Martinez Jul 2007

Palmitoylation And Oxidation Of The Cysteine Rich Region Of Snap-25 And Their Effects On Protein Interactions, Derek Luberli Martinez

Theses and Dissertations

Neurons depend upon neurotransmitter release through regulated exocytosis to accomplish the immense processing performed within the central nervous system. The SNARE hypothesis points to a family of proteins that are thought to enable the membrane fusion that leads to exocytosis. The secondary structure of SNAP-25 is unique among SNARE proteins in that it has two alpha helical SNARE motifs and a cysteine rich (C85, C88, C90, C92) membrane interacting region but notransmembrane domain. The cysteines may be modified by palmitoylation or oxidation but the role of these modifications in vivo is not well understood. Our goal is to elucidate possible …

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Patriarchy And Property: The Nineteenth-Century Mississippi Married Women's Property Acts, Amanda K. Sims Jul 2007

Patriarchy And Property: The Nineteenth-Century Mississippi Married Women's Property Acts, Amanda K. Sims

Theses and Dissertations

The Mississippi Married Women's Property Acts of 1839, 1846, and 1857 reflected the desire of the Mississippi patriarchy to protect themselves from economic instabilities. Analysis of women's deeds in Jefferson county, Mississippi, from 1792 to 1871 and the rulings of the Mississippi High Court of Error and Appeals demonstrate the patriarchy's attempt to balance their desire for preservation of power with honor's demands that patriarchs provide for their families. The MWPA gave women the right to own property in their own names but restricted their ability to use and alienate that property. This made women property owners in name only, …

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Synthesis Of Resveratrol And Its Analogs, Phase-Transfer Catalyzed Asymmetric Glycolate Aldol Reaction, And Total Synthesis Of 8,9-Methylamido-Geldanamycin, Jing Liu Jul 2007

Synthesis Of Resveratrol And Its Analogs, Phase-Transfer Catalyzed Asymmetric Glycolate Aldol Reaction, And Total Synthesis Of 8,9-Methylamido-Geldanamycin, Jing Liu

Theses and Dissertations

The phytoalexin resveratrol and its acetyl analogs have been made using a decarbonylative Heck reaction. The acid chloride derived from 3,5-dihydroxybenzoic acid was coupled with suitable protected 4-hydroxystyrene in the presence of palladium acetate and N,N-bis-(2,6-diisopropylphenyl)-4,5-dihydro imidazolium chloride to give the substituted stilbene in good yield as the key step. Human HL-60 cell assays showed the 4'-acetyl resveratrol variant improved activity (ED50 17 μM) relative to resveratrol (24 μM). Cinchona phase-transfer catalysts (PTC) were developed for glycolate aldol reactions to give differentially protected 1,2-diol products. Silyl enol ether of diphenylmethoxy-2,5-dimethoxyacetophenone reacted to generate benzhydryl-protected products. O-Allyl trifluorobenzyl cinchonium hydrodifluoride (20 …

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Protein Coevolution And Coadaptation In The Vertebrate Bc1 Complex, Kimberly Kay Baer Jul 2007

Protein Coevolution And Coadaptation In The Vertebrate Bc1 Complex, Kimberly Kay Baer

Theses and Dissertations

The cytochrome bc1 complex of the mitochondrial electron transport chain accomplishes the enzymatic reaction known as the modified Q-cycle. In the Q-cycle the bc1 complex transports protons from the matrix to the intermembrane space of the mitochondria, creating the proton gradient used to make ATP. The energy to move these protons is obtained by shuttling electrons from the coenzyme ubiquinol (QH2) to coenzyme ubiquinone (Q) and the mobile cytochrome c. This well studied complex is ideal for examining molecular adaptation because it consists of ten different subunits, it functions as a dimer, and it includes at least five different active …

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