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Articles 31 - 57 of 57
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Optimization And Standardization Of The Oxygen Radical Absorbance Capacity (Orac) Assay, Richard Low, Dr. Tory Parker
Optimization And Standardization Of The Oxygen Radical Absorbance Capacity (Orac) Assay, Richard Low, Dr. Tory Parker
Journal of Undergraduate Research
Antioxidants, when consumed, have the ability to neutralize free radicals, suggesting their presence may protect human physiology from destructive oxidative processes1. Several assays have been developed that quantify the antioxidant capacity of compounds, and one assay that is commonly utilized by researchers and industry is the Oxygen Radical Absorbance Capacity (ORAC) assay2. Despite its popularity, significant differences in reported ORAC values occur between laboratories, leading to difficulties in comparing research. Dr. Parker and his lab conducted a series of tests to attempt to standardize and optimize the ORAC assay.
The Roles Of Phosducin-Like Protein 1 And Programmed Cell Death Protein 5 As Molecular Co-Chaperones Of The Cytosolic Chaperonin Complex, Christopher M. Tracy
The Roles Of Phosducin-Like Protein 1 And Programmed Cell Death Protein 5 As Molecular Co-Chaperones Of The Cytosolic Chaperonin Complex, Christopher M. Tracy
Theses and Dissertations
A fundamental question in biology is how proteins, which are synthesized by the ribosome as a linear sequence of amino acids, fold into their native functional state. Many proteins require the assistance of molecular chaperones to maneuver through the folding process to protect them from aggregation and to help them reach their native state in the very concentrated protein environment of the cell. This study focuses on the roles of Phosducin-like Protein 1 (PhLP1) and Programmed Cell Death Protein 5 (PDCD5) as molecular co-chaperones of the Cytosolic Chaperonin Complex (CCT).Signaling in retinal photoreceptors is mediated by canonical G protein pathways. …
First Principles And Ordinances: The Fourth Article Of Faith In Light Of The Temple, Samuel M. Brown
First Principles And Ordinances: The Fourth Article Of Faith In Light Of The Temple, Samuel M. Brown
Maxwell Institute Publications
Familiarity can lead to a kind of blindness in life and in religion. The first principles and ordinances of the gospel are particularly at risk for neglectful misunderstanding. Author Samuel M. Brown offers a fresh approach by asking how our relationship with God and others can transform our understanding of the gospel basics of faith, repentance, baptism, and the gift of the Holy Ghost. By weaving a tapestry of personal stories, scripture, and history, Brown shows how the truths taught in the highest Temple ordinances relate to the first principles of the gospel. Get to know the Fourth Article of …
Investigating The Effect Of Insurance Fraud On Mouse Usage In Human-Computer Interactions, Martin Hibbeln, Jeffrey L. Jenkins, Christoph Schneider, Joseph S. Valacich, Markus Weinmann
Investigating The Effect Of Insurance Fraud On Mouse Usage In Human-Computer Interactions, Martin Hibbeln, Jeffrey L. Jenkins, Christoph Schneider, Joseph S. Valacich, Markus Weinmann
Faculty Publications
The completion of online forms is the catalyst for many business and governmental processes. However, providing fraudulent information in such forms is pervasive, resulting in costly consequences for organizations and society. Furthermore, detecting fraudulent responses in online forms is often very difficult, time consuming, and expensive. This research proposes that analyzing users’ mouse movements may reveal when a person is being fraudulent. Namely, based on neuroscience and deception theory, the paper explains how deception may influence hand movements captured via the computer mouse. In an insurance fraud context, a study is conducted to explore these proposed relationships. The results suggest …
Reading And Listening To Music Increase Resting Energy Expenditure During Indirect Calorimetry In Healthy Adults , Blaire Snell
Reading And Listening To Music Increase Resting Energy Expenditure During Indirect Calorimetry In Healthy Adults , Blaire Snell
Theses and Dissertations
The Academy of Nutrition and Dietetics has developed an evidence analysis library (EAL) for Nutrition and Dietetics professionals. The EAL is updated by members through workgroups consisting of experts in their fields, most often in response to unanswered questions. One such question is: what kinds of activities can be done during the rest period of an indirect calorimetry test in a healthy population? The objective of our study was to determine if listening to self-selected relaxing music or reading on an electronic device or a magazine effects resting energy expenditure (REE) as measured by an indirect calorimetry test in a …
The Adrenal Cortex Cell Line H295r Releases Interleukin-6, Timothy E. Lindsay, Dr. Allan M. Judd
The Adrenal Cortex Cell Line H295r Releases Interleukin-6, Timothy E. Lindsay, Dr. Allan M. Judd
Journal of Undergraduate Research
Up to this point, the study of adrenal glands has utilized mostly rat and bovine models. However, in the research of human physiology, human models are preferable to animal models. But human adrenal glands are difficult to obtain, and when they are obtained, experiments often have limited sample sizes. In addition, human adrenal glands available for research are often functionally altered by disease. Also, donors with healthy adrenal glands may be administered multiple pharmacological agents which modify adrenal functions. These obstacles show how a model that provides an unlimited quantity of tissue with consistent secretion patterns would take precedent over …
Antibiotic Thin Films, Timothy Jennings, Jason Nielsen, Brian Ratcliff, Nina Wallace, Xin Zhong Lai, Paul B. Savage
Antibiotic Thin Films, Timothy Jennings, Jason Nielsen, Brian Ratcliff, Nina Wallace, Xin Zhong Lai, Paul B. Savage
Journal of Undergraduate Research
Nosocomial infections lead to septicemia, a severe problem in the United States. The Savage group has developed a novel class of antibiotics (CSAs) that can be attached to polymers. Invasive medical equipment can be coated with CSA polymers, forming an antibiotic thin film. Testing has shown the ability of CSA polymers to kill bacteria, which will lead to further testing and future use in the medical field.
What Critical Resources Do Hispanic Women Of Childbearing Age In Utah Need To Promote Adequate Health Care Practices?, Teresa Paredes, Dr. Ana Birkhead
What Critical Resources Do Hispanic Women Of Childbearing Age In Utah Need To Promote Adequate Health Care Practices?, Teresa Paredes, Dr. Ana Birkhead
Journal of Undergraduate Research
The health care practices of Hispanic childbearing age women in Utah affect the overall health care system in Utah. We believe immigrant Hispanic women lack resources (i.e. education, cultural, transportation) to take care of their health and their families. My mentor and I believe the lack of these resources influence Hispanic women’s health status and access to adequate health care. It is crucial for immigrant Hispanic women in Utah to obtain culturally sensitive resources in their communities that will help them learn how to care for their own health and the well-being of their families.
Long-Term Depression Of Excitatory Inputs To Gabaergic Neurons In The Ventral Tegmental Area, Philip J. Sandoval
Long-Term Depression Of Excitatory Inputs To Gabaergic Neurons In The Ventral Tegmental Area, Philip J. Sandoval
Theses and Dissertations
Dopamine cells within the ventral tegmental area of the brain are involved in motivation and reward. Drugs of abuse target these dopamine cells altering their activity and plasticity resulting in addiction. While dopamine cell activity is primarily involved in addiction, the GABA neurons in the VTA have also been shown to have an indirect role. By decreasing the activity of the inhibitory GABA inputs onto dopamine neurons abusive drugs can indirectly increase dopamine cell activity resulting in addictive behaviors. However, although GABA neurons are important in the perception of reward, much less is known about how the excitatory inputs to …
Membrane Properties Involved In Calcium-Stimulated Microparticle Release From The Plasma Membranes Of S49 Lymphoma Cells, Lauryl Elizabeth Campbell
Membrane Properties Involved In Calcium-Stimulated Microparticle Release From The Plasma Membranes Of S49 Lymphoma Cells, Lauryl Elizabeth Campbell
Theses and Dissertations
The mechanism of microparticle shedding from the plasma membrane of calcium-loaded cells has been investigated in erythrocytes and platelets. Recent studies have revealed the physiological and clinical importance of microparticle release from nucleated cells such as lymphocytes and endothelium. The experiments of this study were designed to address whether simple mechanisms discovered in platelets and erythrocytes also apply to the more complex nucleated cells. Four such mechanisms were addressed: potassium efflux, transbilayer phosphatidylserine migration, cytoskeleton degradation, and membrane lipid order. The rate and amount of microparticle release in the presence of a calcium ionophore, ionomycin, was assayed by light scatter …
Automatic Generation Of Music For Inducing Emotive And Physiological Responses, Kristine Perry Monteith
Automatic Generation Of Music For Inducing Emotive And Physiological Responses, Kristine Perry Monteith
Theses and Dissertations
Music and emotion are two realms traditionally considered to be unique to human intelligence. This dissertation focuses on furthering artificial intelligence research, specifically in the area of computational creativity, by investigating methods of composing music that elicits desired emotional and physiological responses. It includes the following: an algorithm for generating original musical selections that effectively elicit targeted emotional and physiological responses; a description of some of the musical features that contribute to the conveyance of a given emotion or the elicitation of a given physiological response; and an account of how this algorithm can be used effectively in two different …
Transgene Delivery Via Microelectromechanical Systems, Aubrey Marie Mueller Wilson
Transgene Delivery Via Microelectromechanical Systems, Aubrey Marie Mueller Wilson
Theses and Dissertations
The invention of pronuclear microinjection initiated the field of transgenic research. Over 30 years later microinjection remains the most straight-forward and most commonly used transgene delivery option. In this work we address the current progress of microelectromechanical systems (MEMS) used as transgenic delivery mechanisms. The nanoinjector is a specially designed MEMS device which uses electrostatic charge to manipulate transgene molecules. The process of nanoinjection was designed as an alternative to microinjection which causes less damage to developing embryos, improves embryo survival, birth rates, and overall efficiency of injections. In vivo testing of nanoinjection demonstrates it is both safe and effective. …
Role Of Ampk In The Upregulation Of Steroidogenic Acute Regulatory Protein In The Zona Fasciculata Of The Adrenal Cortex, Adam Wesley Dayton
Role Of Ampk In The Upregulation Of Steroidogenic Acute Regulatory Protein In The Zona Fasciculata Of The Adrenal Cortex, Adam Wesley Dayton
Theses and Dissertations
Cortisol is a glucocorticoid produced by the zona fasciculata (ZF) of the adrenal cortex. Traditionally, cortisol production and release was seen as being regulated strictly by adrenocorticotropic hormone (ACTH). While this is true of baseline cortisol levels and in response to acute mental stress, the picture is somewhat more complicated in other situations.Interleukin-6 (IL-6) contributes to the maintenance of cortisol levels in situations of prolonged immune or inflammatory stress. AMP activated protein kinase (AMPK) was investigated as a possible mediator of the action of IL-6 or as an independent actor in raising cortisol levels in response to hypoxemic or hypoglycemic …
Development And Use Of A Physiologically Based Mathematical Model Describing The Relationships And Contributions Of Macronutrients To Weight And Body Composition Changes, Saori Sakita
Theses and Dissertations
The effect of the dietary macronutrient composition on weight loss has been a controversial issue for decades. During that time, a high-protein, high-fat, and low-carbohydrate diet has been one of the more popular weight loss diets with the public. We hypothesized that a computer simulation model using STELLA software could help to better understanding the effect of the dietary macronutrient composition on weight loss. We calculated daily total oxidation instead of total energy expenditure as others have done based on the facts that carbohydrate, fat, and protein intake influence carbohydrate, fat, and protein oxidation. In order to create a simple …
Automatic Generation Of Music For Inducing Emotive Response, Tony R. Martinez, Kristine Monteith, Dan A. Ventura
Automatic Generation Of Music For Inducing Emotive Response, Tony R. Martinez, Kristine Monteith, Dan A. Ventura
Faculty Publications
We present a system that generates original music designed to match a target emotion. It creates n-gram models, Hidden Markov Models, and other statistical distributions based on musical selections from a corpus representing a given emotion and uses these models to probabilistically generate new musical selections with similar emotional content. This system produces unique and often remarkably musical selections that tend to match a target emotion, performing this task at a level that approaches human competency for the same task.
Investigating And Modeling Possible Mechanisms By Which Healthy Cell Membranes Become Resistant To Hydrolysis By Secretory Phospholipase A2, Jennifer Nelson
Investigating And Modeling Possible Mechanisms By Which Healthy Cell Membranes Become Resistant To Hydrolysis By Secretory Phospholipase A2, Jennifer Nelson
Theses and Dissertations
Secretory phospholipase A2 (sPLA2) behaves differently toward the membranes of healthy cells compared to those of damaged or dying cells. The enzyme catalyzes rapid and sustained hydrolysis of compromised cells consistent with a simple catalytic mechanism. In contrast, when healthy cells are incubated with sPLA2, they become resistant to hydrolytic attack as manifest by three unusual observations: First, hydrolysis is transient and represents only a small fraction of the total membrane phospholipid content. Second, subsequent addition of sPLA2 fails to generate additional product. Third, the apparent potency of the enzyme to cause the membrane to be refractory is much greater …
Boot Camp For The Psyche: Inoculative Nonfiction And Pre-Memory Structures As Preemptive Trauma Mediation In Fiction And Film, Jacob Michael Hodgen
Boot Camp For The Psyche: Inoculative Nonfiction And Pre-Memory Structures As Preemptive Trauma Mediation In Fiction And Film, Jacob Michael Hodgen
Theses and Dissertations
While some theorists have hinted at various social functions served by the gothic genre—such as providing an outlet for grief, anxiety, and violence in their various forms—recent research within the last few decades into sociology, military science, and trauma studies supplies compelling new ways of rereading the horror genre. In addition to providing an outlet for grief, anxiety, and violence in their various forms, horror media can now be read as a preemptive measure in an effort to mediate the immediate and long-term effects of the trauma and horror faced by humanity. I argue that in much the same way …
Promoting Self-Confidence In Clinical Nursing Students, Karen M. Lundberg
Promoting Self-Confidence In Clinical Nursing Students, Karen M. Lundberg
Faculty Publications
Clinical nursing instructors are continually telling their students that they just need more confidence. But how do students find this needed confidence and how can nursing instructors help them? The author discusses sources and principles of confidence in relationship to teaching behaviors and strategies for increasing self-confidence, such as simulations, peer modeling, story telling, skill review sessions, and journaling.
Amp-Activated Protein Kinase Kinase Activity And Phosphorylation Of Amp-Activated Protein Kinase In Contracting Muscle Of Sedentary And Endurance Trained Rats, Denise Hurst
Theses and Dissertations
This study was designed to examine activity of AMP-activated protein kinase kinase (AMPKK) and AMP-activated protein kinase (AMPK) in muscles from control (C) and endurance trained (T) rats. Rats were trained 5 days/wk, 2 hr/d for 8 wks at a final intensity of 32 m/min up a 15% grade with 30 second sprints at 52 m/min every 10 min. Gastrocnemius muscles were stimulated in situ in T and C rats for 5 min at frequencies of 0.4/sec and 1/sec. Gastrocnemius LKB1 protein, a putative component of the AMPKK complex (LKB1, STRAD, and MO25), increased approximately 2-fold in response to training. …
Studies On Cyclooxygenase-1, Its Structure And Splice Variants, And Modulation Of Cyclooxygenase-2 By Inducible Nitric Oxide Synthase And Novel Phytochemicals., Yibing Xu
Theses and Dissertations
Cyclooxygenases (COXs) are of important therapeutic value as they are the target site of aspirin-like drugs. Here I report nine new COX-1 splice variants in chapter 1, which I characterized with regard to heme-binding and other properties. Inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) are co-inducible in many tissues following mitogenic and proinflammatory stimulation. In chapter 2, I investigate the physical and enzymatic properties of human COX-2 and iNOS and demonstrate that, despite reports to the contrary by another laboratory, they do not interact. The only reported COX-1 splice variant to exhibit cyclooxygenase activity has been isolated from …
Construction Of A Col11a1 Transgene Vector, Cameron Mckell Beck
Construction Of A Col11a1 Transgene Vector, Cameron Mckell Beck
Theses and Dissertations
Background: Cartilage disorders affect millions of people in the United States alone, with effects ranging from poor skeletal development and joint pain to shortened lifespan and perinatal lethality. Many of these disorders have their root in defects of collagen, type XI collagen being among the most important. A mouse model of such a type XI collagen defect is the chondrodysplasia (cho) mutant. Mice homozygous for this null mutation in the Col11a1 gene do not express the α1 chain of type XI collagen. This results in a functional knockout of type XI collagen, leading to insufficient skeletal development and perinatal lethality. …
Prehistoric Timberline Adaptations In The Eastern Uinta Mountains, Utah, Michelle Knoll
Prehistoric Timberline Adaptations In The Eastern Uinta Mountains, Utah, Michelle Knoll
Theses and Dissertations
Excavations at a high altitude archaeological site (3350 m) in the eastern Uinta Mountains, Utah, uncovered at least three ephemeral brush structures. These temporary timberline dwellings are the highest structures excavated in Utah to date. The periods of occupation range from the early Fremont period to the post-contact era. It is believed that the Fremont occupations are logistical in nature, possibly representing male hunting parties. Logistical camps imply a departure from, and return to, a residential camp. Ethnographic studies show that most residential camps are located within proximity to culinary plants to facilitate collection by women. In the Uinta Mountains, …
Multi-Agent Simulations As A Tool For The Assessment Of Urban Microclimate And Its Effect On Pedestrian Behaviour, Michael Bruse
Multi-Agent Simulations As A Tool For The Assessment Of Urban Microclimate And Its Effect On Pedestrian Behaviour, Michael Bruse
International Congress on Environmental Modelling and Software
The urban canopy layer is characterised by a specific climate which significantly differs from theaverage regional climate conditions. Especially inside urban structures such as street canyons, shopping mallsor public places, the local microclimate depends directly on the physical properties of the surrounding surfacesand objects, producing well-known effects such as wind speed decrease, local jets, increased turbulence orincreased thermal loads. These phenomena can have a strong influence on the comfort of pedestrians usingthese areas for different tasks of urban life or leisure activities. Assessing urban climate means to answer thequestion, how the citizens feel under the given circumstances and to decide, …
Visualizing The Relationship Between Speech, Image And Writing, David J. Staley
Visualizing The Relationship Between Speech, Image And Writing, David J. Staley
Comparative Civilizations Review
No abstract provided.
A Friendly Countercomment To Holton, Arthur Iberall
A Friendly Countercomment To Holton, Arthur Iberall
Comparative Civilizations Review
No abstract provided.
Developing My Own Identity As Therapist: A Shaman, Richard C. Ferre
Developing My Own Identity As Therapist: A Shaman, Richard C. Ferre
Issues in Religion and Psychotherapy
No abstract provided.
Sex, Sickness And Statehood: The Influence Of Victorian Medical Opinion On Self-Government In Utah, E. Victoria Grover-Swank
Sex, Sickness And Statehood: The Influence Of Victorian Medical Opinion On Self-Government In Utah, E. Victoria Grover-Swank
Theses and Dissertations
In the struggle for self-government which occupied the Mormon population of Utah between their entry into the Great Basin in 1847 and statehood in 1896, the issue of polygamy dominated public discussion. The non-Mormon population of the United States generally objected to the practice of polygamy, in large part because of Victorian attitudes towards sexual activity and the presumed physical and mental results of violating Victorian sexual norms. It was assumed by most Americans that polygamy, by violating those norms, caused real physical damage to the Latter-day Saints in Utah; damage that disqualified them from holding full and equal political …