Digital Commons Network^™

Recent Advances In Developing Cell-Free Protein Synthesis Biosensors For Medical Diagnostics And Environmental Monitoring, Tyler P. Green, Joseph P. Talley, Bradley Charles Bundy

Faculty Publications

Cell-free biosensors harness the selectivity of cellular machinery without living cells’ constraints, offering advantages in environmental monitoring, medical diagnostics, and biotechnological applications. This review examines recent advances in cell-free biosensor development, highlighting their ability to detect diverse analytes including heavy metals, organic pollutants, pathogens, and clinical biomarkers with high sensitivity and specificity. We analyze technological innovations in cell-free protein synthesis optimization, preservation strategies, and field deployment methods that have enhanced sensitivity, and practical applicability. The integration of synthetic biology approaches has enabled complex signal processing, multiplexed detection, and novel sensor designs including riboswitches, split reporter systems, and metabolic sensing modules. …

Understanding Administrator Approaches To Trauma-Informed Care: Findings From A Mixed Methods Study, Megan Coalwell

Theses and Dissertations

Traumatic events during childhood have been termed adverse childhood experiences (ACEs). Experiencing traumatic events or ACEs is common for school-aged children. Research reports indicate that as many as two out of three children will experience at least one traumatic event by the time they are eighteen. The negative effects of experiencing trauma are well documented. Trauma can lead to long-term outcomes in adults such as chronic health problems, mental health problems, substance misuse, and even early death. During childhood, it can lead to internalizing and externalizing problems, as well as difficulties in school. Trauma-Informed Care (TIC) is an approach to …

An Active Quasi-Circulator Ic And Technique For 1-255 Mhz Resonance-Based Spectroscopic Impedance Plethysmography, Sharisse Poff

Theses and Dissertations

Impedance measurement is a promising avenue for noninvasive glucosemonitoring. Specifically,resonance-basedimpedancemeasurements exhibit good correlation with glucose levels at excitations from tens of MHztoover 100 MHz. Additionally, plethysmographic impedance measurements are needed to separate arterial blood signals, which contain strongerglucose information, frominterstitialfluidsignals. Weanticipate that plethysmographic measurements across a range of frequencies— spectroscopic plethysmography—at excitations from tens to over 100 MHz could enable resonance-based monitoring with higher selectivity for arterial glucose than previous work. Afour-point impedance measurement circuit is designed, and its ability to measure constant and periodically time-varying impedance is demonstrated. This circuit presents high impedance to the device-undertest (DUT), which fails …

Patterns And Continuity: Documenting African American History In Carbon County, Utah, And The Roots Of Racial Terror Lynchings In American Society, Michael L. B. Forvil

Undergraduate Honors Theses

This thesis explores the history of African Americans in Carbon County, Utah, through the lens of racial terror lynching, community memory, and migration. Anchored in the story of Robert Marshall, a Black man lynched in Price, Utah, in 1925, the project considers how racial violence reached beyond the American South and how such acts have been neglected in public memory. Drawing on family history research, census records, historical newspapers, and the work of the Equal Justice Initiative (EJI), this work contextualizes Marshall’s death within broader patterns of racial terror lynchings that shaped African American migration from the South during the …

Hearing From Working Nurses: Incorporating Real-World Knowledge Practices Into The Framework To Better Instruct Tomorrow's Healthcare Professionals, Anne R. Diekema, Elizabeth (Betsy) S. Hopkins, Britt Fagerheim, Brandon Patterson, Nena Schvaneveldt

Faculty Publications

There is a certain duality to the role of librarians in higher education as the job requires preparing students for their current academic work, such as doing research for writing papers, while at the same time preparing students for their future professional information work. Librarians seeking guidance on teaching information literacy more comprehensively are left to study the professional standards of the targeted professional group, and find or carry out research on these practitioners. Synthesizing and translating these findings into instructional approaches while staying true to existing information literacy standards, however, can be challenging. In this chapter we demonstrate how …

Rheumatic Heart Disease In Primary Aged Children In Samoa, Kallysta Lindquist

Undergraduate Honors Theses

Rheumatic heart disease (RHD) is a condition where the heart valves are permanently damaged by an autoimmune response to chronic strep infections. RHD remains extremely prevalent in Oceania - specifically Samoa. However, despite its prevalence, RHD is underexplored in Samoa and there are many disparities for medical care to treat RHD in Samoa. This research shifts the focus of RHD to early detection in children (5-18 years old) and provides critical insights into RHD and the geographic difference in RHD prevalence in Samoa. Our dataset was collected between 2013-2019 from the Rheumatic Relief program done by Brigham Young University. Data …

The Effects Of A Tier 2 Intervention On The Behavior Of Elementary School Students Participating In Second Step: Enhancing A Schoolwide Social-Emotional Learning Curriculum, Charlotte Annalee Kennington

Theses and Dissertations

After reviewing the current research literature on the effects of social-emotional learning (SEL) on the behavior of elementary-age children, it was clear that there was limited research data on the effects of Tier 2 interventions designed to augment the effects of schoolwide SEL programs. Specifically, to what extent could a brief, group-delivered intervention improve the academic engagement, problem behavior, and socially appropriate comments of fifth-grade students receiving schoolwide SEL through Second Step in a traditional public school? Three fifth-grade students were recruited to participate in this study who all engaged in frequent problem behavior during Second Step lessons and throughout …

The Silent Grief Of Grandmothers After An Out-Of-Order Death—An Interpretative Phenomenological Analysis, Jordan Robertson, Elizabeth Cutrer, Paul Caldarella, Jeremy B. Yorgason, Terrell Young, Erjola Gjini, Sarah Stuart, Savannah Tueller

Faculty Publications

This study delves into the lived experiences of grandmothers grappling with grief following the “out-of-order” death of a child, child-in-law, or grandchild, using an Interpretative Phenomenological Analysis grounded in the Dual Process Model-Revised. With 70% of U.S. adults over 65 being grandparents, the research highlights their often-invisible role as both grievers and caregivers amid family loss. Findings reveal three key themes: navigating personal grief, intergenerational support dynamics, and reconstructing family identity. Grandmothers oscillate between loss-oriented and restoration-oriented coping, with grief intensity varying by relational proximity—most profound when losing their own child. They provide emotional and practical support to surviving grandchildren, …

Commitment And Betrayal In Intimate Relationships: A Grounded Theory Analysis, Megan Van Alfen Brown

Theses and Dissertations

Commitment and betrayal are key aspects of a relationship that have impact on the quality or health of the relationship. The purpose of this paper was to use qualitative grounded theory methods to explore how commitment and betrayal are experienced in intimate relationships and to explore the outcomes of both. The data were taken from a larger project on healthy and unhealthy relationships where participants were recruited through convenience and theoretical sampling. Semi-structured interviews were conducted and constructivist grounded theory methods were used to code, generate, and refine prominent categories in the data. Findings revealed that commitment is experienced through …

Belonging Starts With You: Exploring Trust, Belonging, And Spiritual Connection In The Success Of Culturally Diverse Students In Higher Education, Moises Aguirre

Theses and Dissertations

Cultivating trust and belonging is essential for student success in higher education, particularly for students from diverse cultural backgrounds (DCB) who face unique challenges in developing these connections. Research highlights lower levels of trust reported by DCB students toward peers and institutions, adversely impacting their academic performance and social integration (Van Maele & Van Houtte, 2010). The urgency of these issues is underscored by the demographic evolution in Utah's educational system, with projections indicating significant growth of students' diversity by 2065 (Hollingshaus et al., 2019). Because of these projected developments, this study investigates how DCB students conceptualize and experience trust …

The Effects Of An Undergraduate Peer Mentoring Program On Belonging And Success, Alexa Darracq

Theses and Dissertations

The purpose of this study was to determine if participation in an undergraduate peer mentoring program led to increased feelings of belonging and success compared to students who have never received BYU ComD peer mentoring. Outcomes were measured using pre- and post-experiment surveys and focus groups. This study had ten participants in the experimental group and 12 participants in the control group with seven participants from the experimental group who participated in the focus groups. Analysis of the results determined there were three key findings from the study: mentees benefited from the peer mentoring program, students signed up to receive …

Beyond The Pitch: Teaching Emotional Labor In Advertising Education Through An Action Research Program, Michael Joseph Mallory

Theses and Dissertations

As the advertising industry continues to expand, new graduates must navigate the profession in the face of increasing challenges. With competition in the job market growing and Generation Z valuing work-life balance, the advantage of quality advertising education becomes paramount. Current advertising education does not address the challenge of emotional labor that professionals will face in the field. With limited scholarship that explores emotional regulation, communication dynamics, and client relations in an academic advertising setting, emotional labor in advertising education is explored through a thoroughly documented experiential learning study. This study employs Participatory Action Research (PAR) to investigate, develop, and …

The Pressures Experienced By First-Generation Students With Afro-Diasporic Migrant Parents In The University Setting, Bryanna M. Larnyoh

Undergraduate Honors Theses

Guided by a life-reflectance perspective, this thesis investigates the academic and emotional experiences of BYU students with Afro-Diaporic immigrant parents, focusing on how they navigate familial expectations, cultural brokering, and identity formation.

The researcher conducted qualitative research in the form of interviewing five BYU students, born in the United States of America, with Afro-Diasporic migrant parents. By identifying positive and negative effects of their experiences on their socio-emotional health, the results identified commonalities and deviations in the students’ experiences that affect their overall BYU experience and cultural identity awareness.

Illness Severity And Marital Communication In Young Couples: The Moderating Role Of Marital Satisfaction, Jaime Lea Dick

Theses and Dissertations

The emergence of a chronic physical illness is unexpected in emerging adulthood and is accompanied by stress. Additionally, married partners of individuals with physical illnesses are likewise affected by the new diagnosis. Marriage outcomes of couples facing chronic illnesses together vary, being sometimes positive and sometimes negative. The current study examined the relationship between the emergence of chronic physical illness in emerging adults and marital communication of both the patient and partner, with marital satisfaction as a moderator. Gender differences are also addressed. From the Couple Relationships and Transition Experiences (CREATE) study, a nationally representative dataset of newly married emerging …

Performance Analysis Of University Wifi Using 802.11e Information Elements, Douglas Christopher Hales

Theses and Dissertations

Wireless networks, including IEEE 802.11 (WiFi), continue to become more important for many uses, including university classrooms. Factors that impact the performance of these networks have changed greatly over time, with increased scale at which they are used, and growing dependence of latency sensitive applications. In order to better understand the performance of current WiFi networks, a methodology was created to capture and analyze beacon frames with optional 802.11e information elements (IE), using Quality of Service enhanced Basic Service Set or QBSS load (channel utilization) and station count. This methodology is able to collect channel use more frequently than many …

Effects Of Elicitation Method On Functionally Relevant Item Selection In Spanish And English Monolinguals And Bilinguals, Dallin J. Bailey, Esther Barahona Wilkes

Faculty Publications

Purpose: One important decision speech language pathologists make when planning anomia treatment is the identification and selection of the specific vocabulary items to target during therapy. However, this process is not entirely straightforward. Although ‘functional relevance’ has high face validity for the identification of target items, interpretations differ, which may impact which words are selected for therapy. As such, target item selection methods vary, with resulting items impacted by the specific method used. There are also many person-level variables that may impact the functional relevance of specific items, such as the heritage language of the patient or their bilingualism status. …

Integrated Evaluation Of Airtightness, Acoustics, Thermal Performance, And Life-Cycle Carbon Emissions In Code-Compliant Wood-Framed And Thin-Shell Concrete Dome Residential Structures, Eduardo Ibanez Vasquez

Theses and Dissertations

The residential construction industry faces increasing demands for energy-efficient and sustainable housing solutions. In the U.S., residential buildings significantly contribute to energy consumption and greenhouse gas (GHG) emissions, highlighting the need for enhanced building envelope performance. This study compares four residential structures: a traditional code-compliant wood-framed structure built in 1970, a traditional code-compliant wood-framed structure built in 2016, a modular code-compliant wood framed structure built in 2024, and a thin-shell concrete dome built in 2022. The analysis focuses on airtightness, acoustic insulation, passive thermal performance, and life-cycle carbon emissions, including both embodied (cradle-to-gate) and operational energy use. Field-based methods included …

What Strategies Do People With Aphasia With High Basic Psychological Need Satisfaction Report Using? A Qualitative Exploration, Abigail Irene Jensen

Theses and Dissertations

This study explored patterns in the communication strategies reported by people with aphasia with high versus low basic psychological need satisfaction. Participants with aphasia (12 females and 11 males) completed an initial experimental session during which the Basic Psychological Need Satisfaction and Frustration Scale (BPNS/F) was administered. Following this session, participants completed a semi-structured interview in which they described strategies used during daily communication. Each interview was transcribed and analyzed through reflexive codebook analysis, with emphasis placed on the communication strategies they reported using. Participants were grouped according to whether their reported autonomy, competence, or relatedness on the BPNS/F were …

Detection Of Neuron Derived Cfdna In Blood Plasma: A New Diagnostic Approach For Neurodegenerative Conditions, Chad Alan Pollard

Theses and Dissertations

Neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) are characterized by the progressive loss of distinct neuronal subtypes, yet current diagnostic tools are either invasive, limited in resolution, or poorly suited for early detection and longitudinal monitoring. This dissertation began with a proof-of- concept study using bisulfite-PCR at a neuron-enriched locus to detect cortical neuron-derived cell-free DNA (cfDNA) in AD plasma samples, establishing the potential of cfDNA as a marker of neuronal injury. Building on these preliminary findings, a novel framework was developed utilizing Oxford Nanopore Technologies (ONT) to profile genome-wide native DNA …

Granulocyte-Colony Stimulating Factor Effects On The Mesolimbic Dopamine Circuitry And Adaptations With Chronic Ethanol Exposure, Rachel Ji-Hyae Campbell

Theses and Dissertations

The mesolimbic dopamine (DA) system contributes to reward and reinforcement learning for ethanol (EtOH). The nucleus accumbens (NAc) receives DA input from the ventral tegmental area (VTA) encoding rewarding information. Acute EtOH increases NAc DA levels, and this DA response is attenuated with chronic EtOH exposure. Furthermore, chronic EtOH results in reduced DA release, increased DA clearance and presynaptic D2-type auto-receptor sensitization. Further research into EtOH-induced neural adaptations that modulate NAc DA release is explored herein, including changes in cholinergic interneurons (CIN), which are known regulators of DA transmission. One potential class of regulators are immune related cytokines, that can …

An Acoustofluidic Device For Sample Preparation And Detection Of Small Extracellular Vesicles, Jessica F. Liu, Jianping Xia, Joseph Rich, Shuaiguo Zhao, Kaichun Yang, Brandon Lu, Ying Chen, Tiffany Wen Ye, Tony Jun Huang

Faculty Publications

Small extracellular vesicles (sEVs) have emerged as powerful vectors for liquid biopsy, offering a noninvasive window into the dynamic physiological and pathological states of the body. However, to fully leverage the clinical potential of sEV biomarkers, it is imperative to develop robust and efficient technologies for their isolation and analysis. In this study, we introduce a novel sharp-edge acoustofluidic platform designed for rapid and effective sample preparation, coupled with sensitive detection of specific sEV populations based on their surface markers. Our approach utilizes acoustically activated sharp-edge microstructures to concentrate bead-bound sEVs within the microfluidic device, facilitating immediate visualization by fluorescence …

Comunidades Y Vacunas: Findings On Vaccine Hesitancy In Latine Families With Autistic Children, Danica Leticia Limon-Mialkowski

Theses and Dissertations

Parent vaccine hesitancy (VH) and subsequent vaccine refusal for children has escalated in the U.S. over the past several years and is more common among parents with an autistic child compared to the general population (Zerbo et al., 2018). This is an important issue to address given that VH has led to a resurgence of vaccine-preventable diseases (DeStefano & Shimabukuro, 2019; Geoghegan, et al., 2020). Research shows that VH is affected by parent cultural background (Fombonne et al., 2020) and that minoritized groups are more likely to experience VH (48.1% in parents of color [POC] groups versus 22.9% in White …

Picture This: An Event Designed To Increase Awareness Of And Empathy For Individuals Who Experience Scrupulosity, Savannah M. Travis

Undergraduate Honors Theses

Scrupulosity, also known as religious OCD, is often misunderstood and under-recognized by those who have experienced it. This research adopts an interdisciplinary approach, integrating experience design theories and frameworks with research on scrupulosity, to develop an event that aims to increase awareness and empathy among attendees for individuals who experience scrupulosity. The experience design frameworks applied include the design thinking process, the self-determination theory, and the experience-type framework. Current research suggests that there is a need for further research on the case studies and qualitative phenotypes of individuals who have experienced scrupulosity, which this study aims to address.

As part …

The Role Of The Cytosolic Chaperonin Cct In The Folding And Assembly Of G Protein Complexes, Mikaila I. Sass

Theses and Dissertations

All organisms depend on cellular signaling pathways to dictate cell growth, responses to stimuli, and all other cellular functions necessary to maintain health and survival. Many of these signals rely on G protein coupled receptors (GPCRs) and their associated heterotrimeric G proteins for signal detection and transduction. To perform this function, the three subunits of the G protein must be assembled after synthesis on the ribosome. This process requires additional proteins called molecular chaperones to assist in folding of the subunits and assembly into the G protein heterotrimer. Among these chaperones, the cytosolic chaperonin CCT plays an essential role in …

Impact Of Telehealth On Outcomes In Daily Practice, Shannon Stuebs

Theses and Dissertations

While telepsychology has existed in various forms for years and has been researched since the 1960s (Abrams, 2020), it was not until the COVID-19 pandemic that telepsychology started to be widely used. Prior to the COVID-19 pandemic, one study found that psychologists conducted only around 7% of their work via telepsychology, a number that jumped to over 85% in response to COVID-19 (Pierce, Perrin, Tyler, et al., 2020). While there has been a significant increase in the research exploring the efficacy of telehealth since the start of the pandemic (Lin et al., 2022), further research regarding long-term impacts and specific …

Using Web Scraping As A Tool To Collect School Nutrition Data, Aaron Brown

Student Works

Web scraping, a technique for collecting publicly available online data, may facilitate collecting school meal data from large, national samples of school districts in a timely, cost-effective manner. We explore its potential by examining the variation in sodium content of 2 popular entrees served through the US Department of Agriculture’s National School Lunch Program—pizza and chicken nuggets. Daily school menu data were obtained from a national sample of school districts via web scraping. Linking web scraped data to publicly available data on school districts permitted examination of entree sodium content variation across school district geographic and socioeconomic characteristics. Such …

The Detrimental Impact Of Benevolent Sexism On Women, Lucy Jessee

AWE (A Woman’s Experience)

Sexism is often defined as negative attitudes toward or discrimination against a person because of their sex or gender identity. This issue is well known and frequently discussed in schools, politics, social situations, and popular culture; however, not many people understand that sexism can come in many forms. Hostile sexism, the more commonly imagined type of sexism, consists of blatantly derogatory, exclusive, or antagonistic attitudes or actions toward women. This can take many forms, such as negative stereotypes regarding women’s competence, degradation of a woman’s worth or value, violence against women, or limitation on a woman’s opportunities because of her …

Full Issue, Vol. 16

Monographs of the Western North American Naturalist

No abstract provided.

Front Matter, Vol. 16

Monographs of the Western North American Naturalist

No abstract provided.

Full Issue

AWE (A Woman’s Experience)

No abstract provided.