Digital Commons Network^™

Signal Integration: How It Changes Across Cell Types In The Vestibulo-Ocular Reflex, Alisa Burt, Trace Stay

Library/Life Sciences Undergraduate Poster Competition 2025

The Vestibulo-ocular reflex (VOR) is a reflex that controls eye movements in order to keep images stable on the retina. The precise circuitry behind the VOR is not well understood. Using awake in-vivo recording and high-density neural probes, this study aims to identify how signal integration varies across cell types.

Research Process Toward The Creation Of Transgenic Beetles, Taylor Coffman, Christian Mccombs, Jonah Jex, Chris Daley, Brian D. Jensen, Sandra Hope Ph.D

Library/Life Sciences Undergraduate Poster Competition 2025

Create a generalized efficient procedure for the reliable creation of transgenic insects.

Prelanding Movement Differences In Joint Kinematics In Chronic Ankle Instability With And Without Ankle Swelling, Brayden Phillips, Hyunwook Lee, Seunguk Han, Minsub Oh, J. Ty Hopkins

Library/Life Sciences Undergraduate Poster Competition 2025

• Lateral ankle sprains (LASs) are one of the most common lower extremity injuries1 and develop into chronic ankle instability (CAI) up to 74% of the time.1
• Approximately 40% of CAI individuals suffer from persistent swelling after lateral ankle sprains.2,3
• Swelling results in an inability to contract at a normal level surrounding joint musculature.4
• Athrogenicmuscle inhibition (AMI) plays a central role in altered neuromuscular control, which may result in altered neuromechanicsand increased susceptibility to joint injury.4

Optimizing Carbon Nanotube Diameter And Copper Coating To Inhibit Pseudomonas Aeruginosa Biofilm Growth, Owen Cramer, Jenny Finlinson, Lucy C. Bowden, Bradford K. Berges Ph.D.

Library/Life Sciences Undergraduate Poster Competition 2025

• ~30% of surgical implant failure is caused by infection¹
• 10-23% of all implant-associated bone and joint infections are caused by gram-negative bacteria²
• Pseudomonas aeruginosa, a gram-negative bacterium, forms biofilms (bacterial communities encased in a matrix) that are extremely difficult to treat
• Carbon-Infiltrated Carbon Nanotubes (CICNT) have a surface structure that prevents the formation of biofilms³
• The mechanism of biofilm disruption on CICNT is still unknown.
• Our current research is focused on creating the optimal CICNT conditions that result in the greatest reduction of adherent P. aeruginosa.

Invasive Species And Water Loss: Automating The Study Of Phragmites In Utah Wetlands, Alexander Atkinson, Dr. Rachel Wood

Library/Life Sciences Undergraduate Poster Competition 2025

Phragmites australis is an invasive reed threatening Utah wetlands by not only outcompeting native flora and disrupting ecological system but also potentially increasing evapotranspiration (ET), the combined process of evaporation and plant transpiration. Increased ET may accelerate water loss in the already shrinking Great Salt Lake (GSL), exacerbating ecological and economic consequences.

To address this, we are developing an automated R-based data analysis pipeline to analyze Utah Geological Survey (UGS) data at the GSL Phragmites site, and to validate evapotranspiration measurements with satellite estimates from OpenET. By making the data and analyses easily accessible, we can better understand and mitigate …

Effect Of Isostatic Rebound On Soil Biodiversity, Robert Candland, Blake Harrison, Solinus Farrer, Kyle Lake, Byron Adams

Library/Life Sciences Undergraduate Poster Competition 2025

Purpose: Understand the effect of shifting tide lines on organism diversity and abundance

Parthenogenetic Pathways: Investigating The Expansion Of A Clonal Whiptail, Jordan Kirk, Vicente Fernandez Lara, Angelina Romero, Dallin Matthews, Reagan Mckee, Randy Klabacka

Library/Life Sciences Undergraduate Poster Competition 2025

Non-native species are defined as species who live in any area outside of their native range, and they often have unique adaptational strategies to be able to populate various areas, even those different from their native habitat

The New Mexico Whiptail (Aspidoscelis neomexicanus) is a parthenogenetic (asexual) species of lizard of family Teiidae. It’s native range extends from central to south-central New Mexico [1]

Parthenogenetic species can colonize/invade new territories easily due to their ability to reproduce asexually [4]

Established populations of this species of lizard in multiple localities outside of their native range have been identified in …

Engineering Chimeric Autoantibody Receptor T Cells (Caar): A Potential Cure For Graves' Disease, Kimbal Demars, Abigail Cheever, Chloe Kang, Hunter Lindsay, Mackenzie Hansen, Kim O'Neill, Scott Weber

Library/Life Sciences Undergraduate Poster Competition 2025

• Graves’ Disease (GD) is the 4th most common autoimmune disease in the United States.
• GD is characterized by autoreactive B cells releasing anti-thyroid stimulating hormone receptor (TSHR) Ab that bind to TSHR, causing an overexpression of hormones.
• Excessive hormonal release leads to hyperthyroidism, causing a variety of metabolic issues.
• No cure exists, only limited effectiveness of treatments, including chemotherapy, radiation, or thyroidectomy.
• Chimeric antigen receptors (CAR) T cell therapy has been effective in treating blood cancers.
• Modifying this therapy by engineering T cells that replace the antigen as the T cell receptor will selectively target autoreactive B cells, namely chimeric …

End Epilepsy: Human And Rodent Seizures Demonstrate A Dynamic Interplay With Spreading Depolarizations, Daniel Hummel, Jacob H. Norby, Noah Ricks, John D. Rolston, Shervin Rahimpour, Juha Voipio, Andrew J. Trevelyan, Elliot H. Smith, Ryley Parrish

Library/Life Sciences Undergraduate Poster Competition 2025

Affecting more than 50 million people worldwide, Epilepsy is a condition of repeated seizures. Seizures (Sz) occur when brain cells transmit uncontrolled electrical signals, and most often terminate on their own, but how this happens is unknown. A proposed mechanism of Sz termination is a spreading depolarization (SD). A SD is a wave that travels through the brain, suppressing brain activity. Currently, the relationship between SDs and seizures is not well understood. The goal of this study was to understand how the two phenomena interact in both rodent brains, and humans. Better understanding of SDs may lead to the development …

Enabling Better Interoperability And Reusability For Down Syndrome Transcriptomic Datasets, Harrison Oaks, Garrett L. Wride, Stephen Piccolo

Library/Life Sciences Undergraduate Poster Competition 2025

Introduction: Gene expression profiling has become a cornerstone of biomedical research, offering relevant insights into the molecular mechanisms that underlie complex conditions such as Down syndrome (DS), a condition caused by trisomy 21. RNA expression data from individuals with DS have highlighted critical pathways involved in development, immune function, and disease susceptibility. Despite the availability of over 100 publicly shared RNA expression datasets, their potential remains underutilized due to inconsistent metadata, diverse normalization protocols, and varying data quality. Addressing these barriers is vital to enabling researchers to standardize, integrate, and analyze datasets effectively. We do this by creating a data …

Effects Of Predation On Cognition In Brachyrhaphis Rhabdophora, Elizabeth F. Jenkins, Jerald B. Johnson

Library/Life Sciences Undergraduate Poster Competition 2025

Does predation environment affect the cognitive abilities of the tropical fish Brachyrhaphis rhabdophora?

Effects Of Ethanol On G-Csf Sensitivity In The Ventral Striatum, Kaleb Gardner, Rachel Campbell, Camryn Holt, Zachary Valentine, Chase Seiter, Jordan T. Yorgason

Library/Life Sciences Undergraduate Poster Competition 2025

Granulocyte-colony stimulating factor (G-CSF) is a known neuromodulator for dopamine (DA) release in the ventral striatum • Increased peripheral G-CSF levels enhances abused substance effects • The G-CSF mechanism for enhancing release remains unknown • How ethanol affects G-CSF neuromodulation also remains unknown • The present studies examined G-CSF effects on striatal and mesolimbic circuitry and chronic ethanol effects on this system

Effects Of Acute Injections Of Etoh In Cytokine Release In Mice, Alina Svitlana Rodriguez Bezruchko, Alka Gaur, Carlos M. Moreno, Jordan T. Yorgason, Scott Weber

Library/Life Sciences Undergraduate Poster Competition 2025

To learn the pathway by which the peripheral immune system interacts with dopaminergic neurons and triggers an addiction response, we compared cytokine and chemokine production levels before and after a 20-minute ethanol injection. Since some cytokines and chemokines can cross the blood-brain barrier, their peripheral production may influence neural activity. We had four groups: ethanol, saline, domperidone-ethanol, and domperidone-saline. As domperidone is a dopamine antagonist, we will use it as a control to verify that the change in cytokine production is due to ethanol rather than other factors.

Discovering Diet-Dependent Changes In Amino Acid Metabolism, Benjamin Driggs, Coleman Nielsen, J. C. Price

Library/Life Sciences Undergraduate Poster Competition 2025

The Price Lab ran a mouse diet experiment to see if we could detect changes in amino acid metabolism according to diet. The diets used were low protein ad libitum (LP AL), low protein CR (LP CR), high protein ad libitum (HP AL), and high protein CR (HP CR). Multiple individuals were randomly assigned to each diet. Extracting D2O labelled samples across several time points allows us to use mass spectrometry to measure both protein concentration and turnover (figure 1) (1). These are measured by analyzing the shift in isotopic peaks (2). Using these changes in isotopic peaks we can …

Digital Vs. In-Person Interaction: Preventing Suicide In Autistic And Socially Anxious Populations, Jacob Griffin, Jared Nielson

Library/Life Sciences Undergraduate Poster Competition 2025

Introduction: Suicide is one of the leading causes of death in the U.S. and the third leading cause of death for individuals from 15 to 29-year-olds world-wide (Suicide Data and Statistics, 2024; World Health Organization: WHO, 2024). As prevalent as suicide is among general populations, statistics have shown that the risk is even greater among certain groups such as autistic populations and socially anxious populations. Autism Spectrum Disorder (ASD) is a neurological and developmental disorder which affects communication, behavior, and learning abilities (Autism Spectrum Disorder, 2024). One study reported that individuals with ASD were almost three times more likely to …

Different Phase, Same Results: No Metabolic Variation Across Phases Of The Menstrual Cycle, Grace Loveless, Hadley Peay, Jessica Linde, Kiese Mpongo, Joran Quirante, Arianna Young, Devon Wardell, Audrey Newman, Mohadesah Ahmadi, Gary Mack, Jayson Gifford

Library/Life Sciences Undergraduate Poster Competition 2025

BACKGROUND: Even with gender parity being achieved in the 2024 Paris Olympic games with 50% male and female athletes(Forbes 2024), female subjects are often excluded from exercise performance research studies. Cowley et al.(2021) found that there was a significant difference between female (34%) and male (66%) participants in sport and exercise research. One reason for exclusion of females in physiology research is uncertainty regarding the impact of the menstrual cycle (MC) on exercise performance and metabolic measures.

Development Of Seed Coating Technologies & Seeding Techniques To Improve Wildlife Habitat In The Sagebrush Steppe, Sage Johansen, Curtis Garlick, Corban Gibson, John Stromberg, Ryan Glover, Nathaniel Adams, April Hulet, Matthew Madsen

Library/Life Sciences Undergraduate Poster Competition 2025

The sagebrush steppe biome is disappearing at a rate exceeding 500,000 hectares per year. Restoring these degraded areas through the reseeding of native vegetation is essential for preserving wildlife habitat and maintaining critical ecosystem services. However, seeding efforts often end in failure, especially in hotter and drier parts of the sagebrush steppe.

Rangeland seeds typically are sown near the soil surface, where the seed and unemerged seedlings experience high mortality due to factors such as seed predation, drought, freeze-thaw cycles, and pathogens. Seedlings also struggle to emerge from the soil due to soil crusting.

However, if it were possible to …

Developement Of A Rodent Virtual Reality System For Measuring Reward, Aman Malhotra, Joe Davis, Jacob Cecil, Lauren Ford, Daniel-Luke Isemonger, Noah Moffat, Ryan Powers, Cody Siciliano, Ryan West, Jordan T. Yorgason

Library/Life Sciences Undergraduate Poster Competition 2025

Rodent VR is a tool for drug impact studies involving VR and optical imaging on motivation-related circuits using customizable maze creation and a comprehensive analysis program. We are using this combined with a GRINS lens surgical implant to gather real time data.

Competitive Bacteria Inhibiting Yersinia Ruckeri Growth – A Strategy To Prevent Enteric Redmouth Disease (Erm) In Freshwater Fish, Kyler Linton, David Erickson

Library/Life Sciences Undergraduate Poster Competition 2025

Pacific freshwater fish are less likely than Atlantic freshwater fish to exhibit Enteric Redmouth Disease (ERM), or Yersiniosis as caused by Yersinia ruckeri. Based on the hypothesis that these fish may harbor commensal bacteria that inhibit Y. ruckeri growth, we isolated many kinds of commensal bacteria from fish intestines that we have collected from Alaska and local streams. Using co-culture experiments, we have conducted competitive assays to determine if the bacteria found in the gut biomes of these fish inhibit the growth of Y. ruckeri. These may be potential probiotic organisms that could provide resistance to ERM disease.

Comparing Management Strategies For Gray Wolves, Dingoes, And African Wild Dogs: Insights For U.S. Wolf Conservation, Joshua Jewell, Tom Smith

Library/Life Sciences Undergraduate Poster Competition 2025

Europe, Africa, and Australia can provide insights into USA Gray Wolf Management.

Comparative Whole Genome Sequencing Of Cryopreserved And Ffpe Cancer Tissue, Delaney Anderson, Ken Dixon, Ryan Miller, Sangmoon Lee, Jeffrey Okojie, Jared Barrott

Library/Life Sciences Undergraduate Poster Competition 2025

Whole genome sequencing (WGS) determines the DNA sequence of an organism’s entire genome & plays a key role in cancer precision medicine

• Currently, the main preservation method of cancer tissue for WGS is formalin-fixed, paraffin-embedded (FFPE) tissue; cryopreserved (CP) tissue is not routinely used in clinical settings
• Previous studies have determined CP tissue yields higher quality & quantity of DNA
• This study aimed to compare the outcomes of WGS in CP & FFPE samples.

Chilling Insights: A Comparative Study Of Cancer Tissue Preservation, Rebecca Bascom, Paige Nelson, Jacob Harris, Jack Davis, Mackenzie Burr, Jeffrey Okojie, David Booker, Ken Dixon, Jared Barrott

Library/Life Sciences Undergraduate Poster Competition 2025

It is a fact that personalized cancer treatment leads to better patient outcomes. But what if the current treatments aren't as personalized as they could be?

Clinical cancer tissue samples are typically sent to labs as formalin-fixed and paraffin-embedded (FFPE) tissues. A recent study4 indicates that cryo-preserved (CP) tissues offer significantly better DNA quality and quantity than FFPE samples, suggesting a need to reevaluate preservation methods. We aim to expand this research by comparing protein expression in FFPE and CP samples.

Specifically, we will focus on PD-L1, a protein that inhibits T-cells and is overexpressed in all cancer cells. The …

Barks Vs Bears: A Ruff Reality, Fern Luttrell, Tom Smith, Stephen Herrero, Lana Ciamiello, Hank Hristienko, Erin Jacoway, Linda Wiggins

Library/Life Sciences Undergraduate Poster Competition 2025

• Will your dog protect you from a bear?
• Do dogs provoke bear attacks?
• Is it safe for your dog to be in bear country?

Assessing Sandy Beach Health Throughout The South Atlantic Bight With Ghost Crabs, Raquel Wilson, Blaine D. Griffen

Library/Life Sciences Undergraduate Poster Competition 2025

To better inform the management and protection of marine ecosystems, we examined human impacts on sandy beach health across the South Atlantic Bight by assessing the abundance and size of ghost crab burrows, and habitat quality. We used an urbanization index to measure the level of human impact. Sandy beach ecosystems are ecologically and economically important, yet they face immense pressure from increasing human activity^1,2. Protecting these ecosystems is critical yet challenging due to their large size, but we can evaluate their health and the extent of human impact using a bioindicator species. We used the Atlantic ghost …

Arid1a Knockout: A Catalyst For Osteosarcoma Progression, Alma Taggart, Peyton Worley, Heinen Louis, Emilee Nielson, Jared Barrott

Library/Life Sciences Undergraduate Poster Competition 2025

Osteosarcoma (OS) is a rare form of bone cancer, with high mortality rates in children and young adults. Current OS research has been limited by a lack of mouse models that accurately represent the metastatic and chemoresistant nature of this cancer. Furthermore, by focusing on patient-derived xenograft models it limits the applications of novel immunotherapies because these mouse models lack a competent immune system. By knocking out Arid1a, we generated a mouse model that more accurately reflects the aggressive nature of the tumor with 100% penetrance of tumorigenesis and 41% penetrance of metastasis, while maintaining a competent immune system. This …

Acee And Pflb: Interference In Oxygen Independent Or Dependent Metabolic Pathways Affect Virulence Of P. Carotovorum, Ethan Shreeve, Foxx Naylor, Jeffrey Schachterle

Library/Life Sciences Undergraduate Poster Competition 2025

Pectobacterium carotovorum is a plant-pathogenic bacterium, causing soft rot diseases in vegetables such as potatoes and carrots. Mainly, this is achieved by the production of plant cell walldegrading enzymes, allowing for invasion of host cells. The general mechanisms underlying the pathogenicity of P. carotovorum are well characterized, but the phenotypic effects of some core metabolic processes are not. An important part of metabolism in bacteria is pyruvate production and utilization as a metabolic intermediate. P. carotovorum has two critical genes— pflB and aceE—that play roles in directing pyruvate metabolism. PflB encodes pyruvate formate-lyase, enabling the bacterium to convert pyruvate into …

Where The Green-To-Red Neurexin Grows: Analyzing Neurexin-3a Expressing Neurons Through Dendra2 Knock-Ins And Full Locus Deletion, Dillon J. Brown, Isaac E. Greenwood, Annalie Martin, Arminda Suli Ph.D.

Library/Life Sciences Undergraduate Poster Competition 2025

The optic tectum (OT) is a zebrafish midbrain structure homologous to the mammalian superior colliculus (SC). The OT facilitates integration of multisensory input and coordinates a corresponding involuntary response. Single-cell RNA sequencing data from our lab indicates the differential expression of the presynaptic cell adhesion protein - neurexin3a - within two cell populations (OT5 and OT8) of the zebrafish OT. The SC and neurexin3a have both been implicated in autism spectrum disorder (ASD), warranting, therefore, a further investigation. To visualize neurexin3a positive neurons in the OT, we are generating a transgenic zebrafish line that expresses the green-to-red photoconvertible protein Dendra2 …

Using Neuroscience To Understand Food, Tyler Thronton, Jonathan Kershaw

Library/Life Sciences Undergraduate Poster Competition 2025

Food liking is determined by evaluation and reward centers in the brain. Few studies have observed the magnifying effects that messages have on taste liking as participants try food in a neuroimaging setting.

Walking In Super Shoes: Reduced Ankle Power, Decreased Stability?, Bethany Esplin, Thomas Anderson, Nate Jacobsen, Luke Vankeersbilck, Dustin A. Bruening, Iain Hunter

Library/Life Sciences Undergraduate Poster Competition 2025

Super shoes improve running economy by reducing gastrocsoleus work [1]

Could the same benefit apply to walking to benefit clinical populations?

Is there a trade-off for balance?

Synthesis Of Gold Nanorods As Payloads For Antibody Drug Conjugates For Synovial Sarcoma, Melanie I'Anson-Holton, Andralyn Anmckell, John Hanosek, Jeffrey Okojie, Bridger Kearns, Jared Barrott

Library/Life Sciences Undergraduate Poster Competition 2025

Antibody-drug conjugates (ADC) are burgeoning class of anti-cancer therapies. They rely on the specificity of antibodies to selectively deliver a cytotoxic payload to cancer cells expressing unique antigens. To minimize the toxicity of these ADCs, we designed a multipronged application with two separate components that by themselves are harmless, but when combined result in thermal toxicity to the tumor cells. Gold nanoparticles as the payload was one component and a near IR laser was the other. Gold nanoparticles are innocuous and exhibit localized surface plasmon resonance (LSPR). The LSPR of gold nanoparticles allows them to absorb photons at certain wavelengths, …