Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Other

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type

Articles 22831 - 22860 of 25729

Full-Text Articles in Entire DC Network

Cgmp Recombinant Fix For Iv And Oral Hemophilia B Therapy, William H. Velander Principal Investigator, Abramson Stephan Lead Investigator, Cooper Julian Lead Investigator, William Dernell Key Person, Mark Manning Lead Investigator, Michael Meagher Lead Investigator, Paul Mohanan Lead Investigator, Timothy Nichols Lead Investigator, Todd Swaanson Key Person, Kevin E. Van Cott Sep 2005

Cgmp Recombinant Fix For Iv And Oral Hemophilia B Therapy, William H. Velander Principal Investigator, Abramson Stephan Lead Investigator, Cooper Julian Lead Investigator, William Dernell Key Person, Mark Manning Lead Investigator, Michael Meagher Lead Investigator, Paul Mohanan Lead Investigator, Timothy Nichols Lead Investigator, Todd Swaanson Key Person, Kevin E. Van Cott

Department of Chemical and Biomolecular Engineering: Funded Proposals

Three specific aims are proposed: Specific Aim # 1. Process engineer and scale-up the recovery and purification of transgenic recombinant human Factor IX. The University of Nebraska-Lincoln Biological Process Development Facility will complete process development and scale-up, and produce clinical grade materials for preclinical studies. The endpoint is a proposed final product specification to help facilitate transfer to current Good Manufacturing Practices compliant production of clinical grade material to support an Investigational New Drug filing with the United States Food and Drug Administration (FDA) leading to clinical trials. Specific Aim #2. Characterize and formulate transgenic recombinant human Factor IX for …

Go to article

Fitness Consequences Of Anopheles Gambiae Population Hybridization, David M. Menge, Tom Guda, Daibin Zhong, Aditi Pai, Goufa Zhou, John C. Beier, Louis Gouagna, Guiyun Yan Sep 2005

Fitness Consequences Of Anopheles Gambiae Population Hybridization, David M. Menge, Tom Guda, Daibin Zhong, Aditi Pai, Goufa Zhou, John C. Beier, Louis Gouagna, Guiyun Yan

All Peer-Reviewed Publications

Background: The use of transgenic mosquitoes with parasite inhibiting genes has been proposed as an integral strategy to control malaria transmission. However, release of exotic transgenic mosquitoes will bring in novel alleles along with parasite-inhibiting genes that may have unknown effects on native populations. Thus it is necessary to study the effects and dynamics of fitness traits in native mosquito populations in response to the introduction of novel genes. This study was designed to evaluate the dynamics of fitness traits in a simulation of introduction of novel alleles under laboratory conditions using two strains of Anopheles gambiae: Mbita strain from …

Go to article

California Consumers' Sentiment Plummets, Chapman University Media Relations Sep 2005

California Consumers' Sentiment Plummets, Chapman University Media Relations

Chapman Press Releases 2003-2011

No abstract provided.

Go to article

Developing A Creator Based World View, Steve W. Deckard Sep 2005

Developing A Creator Based World View, Steve W. Deckard

Faculty Publications and Presentations

No abstract provided.

Go to article

Protein-Protein Interaction Map Of The Trypanosoma Cruzi Ribosomal P Protein Complex, Maximiliano Juri Ayub, Cristian R. Smulski, Benson Nyambega, Natalia Bercovich, Dan Masiga, Martín P. Vazquez, Carlos F. Aguilar, Mariano J. Levin Sep 2005

Protein-Protein Interaction Map Of The Trypanosoma Cruzi Ribosomal P Protein Complex, Maximiliano Juri Ayub, Cristian R. Smulski, Benson Nyambega, Natalia Bercovich, Dan Masiga, Martín P. Vazquez, Carlos F. Aguilar, Mariano J. Levin

All Peer-Reviewed Publications

The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. Four out of five ribosomal P proteins of Trypanosoma cruzi, TcP0, TcP1α, TcP2α, and TcP2β had been previously characterized. Data mining of the T. cruzi genome data base allowed the identification of the fifth member of this protein group, a novel P1 protein, named P1β. To gain insight into the assembly of the stalk, a yeast two-hybrid based protein interaction map was generated. A parasite specific profile of interactions amongst the ribosomal P proteins of T. cruzi was evident. The TcP0 …

Go to article

'Field Linguistics' Takes Researchers To All Parts Of The Globe, David J. Silva Sep 2005

'Field Linguistics' Takes Researchers To All Parts Of The Globe, David J. Silva

Linguistics & TESOL Faculty Publications & Presentations - Archive

No abstract provided.

Go to article

Improving The Quality Of Low Bitrate Lpc Speech Codec Using Gamma-Chirp Filterbank, Amin Khajeh Djahromi Sep 2005

Improving The Quality Of Low Bitrate Lpc Speech Codec Using Gamma-Chirp Filterbank, Amin Khajeh Djahromi

Electrical Engineering Theses - Archive

In this thesis, two methods for getting higher speech quality in low bit-rate LPC coder in comparison with the original LPC coder were presented. In order to improve the quality of the speech, the embedded method which can take the place of the traditional synthesis algorithm in LPC coders and the post-processing method that also can be used as the last stage in the LPC-coder based systems were proposed. In the embedded method, the result of MOS test of the synthesized speech increased by 0.8 and in the post-processing method the result of MOS test of the synthesized speech increased …

Go to article

The Effect Of Host Larvae On Three Psyttalia Species (Hymenoptera: Braconidae), Parasitoids Of Fruit-Infesting Flies (Diptera: Tephritidae), M. K. Billah, S. Kimani-Njogu, W. A. Overholt, R. A. Wharton, D. D. Wilson, M. A. Cobblah Sep 2005

The Effect Of Host Larvae On Three Psyttalia Species (Hymenoptera: Braconidae), Parasitoids Of Fruit-Infesting Flies (Diptera: Tephritidae), M. K. Billah, S. Kimani-Njogu, W. A. Overholt, R. A. Wharton, D. D. Wilson, M. A. Cobblah

All Peer-Reviewed Publications

Three species of fruit fly parasitoids, Psyttalia concolor (Szépligeti), Psyttalia cosyrae (Wilkinson) and Psyttalia lounsburyi (Silvestri) (Hymenoptera: Braconidae) were reared on different host larvae to determine the effects of host species, size and colour on parasitoid development. Ovipositor, ovipositor sheath and hind tibia lengths were found to be different for progenies from preferred and non-preferred host larvae. Ratios of ovipositor-tibia and ovipositor sheath-tibia showed no difference when P. concolor was reared on a bigger host (Ceratitis cosyra (Walker) (Diptera: Tephritidae), whereas rearing P. cosyrae on a smaller host (C. capitata (Wiedemann) showed significant differences. Comparison of the linear measurements, ratios …

Go to article

Termite (Isoptera) Diversity In Senegal And Their Damage On Reforestation Areas And Cultures, Makhfousse Sarr, Nguya K. Maniania, A. Russell-Smith, Abdoulaye Niassy Sep 2005

Termite (Isoptera) Diversity In Senegal And Their Damage On Reforestation Areas And Cultures, Makhfousse Sarr, Nguya K. Maniania, A. Russell-Smith, Abdoulaye Niassy

All Peer-Reviewed Publications

Studies conducted from 1969 to 2000 on termite ecology and biology in Senegal revealed high termite diversity and an influence of climate and soil conditions on termite group distribution. Sixty-four termite species were recorded. Some were specific to ecologically similar zones while others were widely distributed. Some species, known to inhabit wet zones, were found in semi-arid zones where relic forest vegetation still exists. Nioro, in the central part of the country, seems to be the buffer zone between species to the north and south of Senegal. In Ferlo, an arid zone, Macrotermes species was in regression and the subsisting …

Go to article

Repellency Of Essential Oils Of Some Plants From The Kenyan Coast Against Anopheles Gambiae, Josiah O. Odalo, Maurice O. Omolo, Hamisi Malebo, John Angira, Patrick M. Njeru, Isaiah O. Ndiege, Ahmed Hassanali Sep 2005

Repellency Of Essential Oils Of Some Plants From The Kenyan Coast Against Anopheles Gambiae, Josiah O. Odalo, Maurice O. Omolo, Hamisi Malebo, John Angira, Patrick M. Njeru, Isaiah O. Ndiege, Ahmed Hassanali

All Peer-Reviewed Publications

Volatile oils extracted by hydrodistillation from six plant species growing in the Kenyan coast, Croton pseudopulchellus Pax, Mkilua fragrans Verdc. (Annonaceae), Endostemon tereticaulis (poir.) Ashby, Ocimum forskolei Benth., Ocimum fischeri Guerke and Plectranthus longipes Baker (Labiateae), were evaluated for repellency on forearms of human volunteers against Anopheles gambiae sensu stricto. All oils were found to be more repellent (RC50 range = 0.67-9.21 × 10-5 mg cm-2) than DEET (RC50 = 33 × 10-5 mg cm-2). The individual components of the oils were identified by GC-MS and GC co-injections with authentic standards. The repellency of 15 of the main constituents of …

Go to article

Thea1010 - Understanding Theatre, Fall 2005, David Sidwell Aug 2005

Thea1010 - Understanding Theatre, Fall 2005, David Sidwell

Theatre Arts - OCW

The goal of this course is to understand the arts of theatre, their application to daily life and to the enjoyment of theatre as an art form.

Go to article

Inst7150 - Advanced Topics In Learning Object Design And Reuse, Fall 2005, David Wiley Aug 2005

Inst7150 - Advanced Topics In Learning Object Design And Reuse, Fall 2005, David Wiley

Instructional Technology & Learning Sciences - OCW

This course is designed to help you understand and apply advanced topics in the design, creation, and reuse of learning objects. The course is structured around a practical, hands-on project using learning objects, intermingled with readings and discussion on a variety of topics.

Go to article

Growth And Water Relations Of Littleleaf Linden Trees Established In Irrigated Buffalograss And Kentucky Bluegrass, J. Ryan Stewart, Roger Kjelgren, Paul G. Johnson, Michael R. Kuhns Aug 2005

Growth And Water Relations Of Littleleaf Linden Trees Established In Irrigated Buffalograss And Kentucky Bluegrass, J. Ryan Stewart, Roger Kjelgren, Paul G. Johnson, Michael R. Kuhns

Plants, Soils, and Climate Faculty Publications

Although transplanted trees typically establish and grow without incident in frequently irrigated turfgrass, their performance in precisely irrigated turfgrass in an arid climate is not known. We investigated the effect of precision irrigation scheduling on growth and water relations of balled-and-burlapped littleleaf linden (Tilia cordata Mill. `Greenspire') planted in buffalograss (Buchloë dactyloides [Nutt.] Engelm. `Tatanka') and kentucky bluegrass (Poa pratensis L.). Over 2 years, trees in turfgrass were irrigated either by frequent replacement based on local reference evapotranspiration, or precision irrigated by estimating depletion of soil water to the point of incipient water stress for each turfgrass species. Predawn leaf …

Go to article

An Experimental Investigation Of Ionization Of Supersonic Air By A Corona Discharge, Udyavar S. Satyanand Aug 2005

An Experimental Investigation Of Ionization Of Supersonic Air By A Corona Discharge, Udyavar S. Satyanand

Mechanical and Aerospace Engineering Dissertations - Archive

A technique is developed to ionize supersonic air flow in a shock tube by a weak corona discharge. The driven section of the tube is open to the atmosphere. The shock propagates in the driven section at about 1 km/s by means of an area contraction near the downstream end of the driven section. Air is ionized by a unipolar corona discharge device comprising of a sharp-edged wedge as a high-field electrode inserted in a 41.25 mm (2 in.) ID tube that forms a low-field electrode. The device requires less than 0.5 W. A ring probe, downstream of the corona …

Go to article

Integration Of The Sam-Grid Infrastructure To The D0 Data Reprocessing Effort, Anoop Rajendra Aug 2005

Integration Of The Sam-Grid Infrastructure To The D0 Data Reprocessing Effort, Anoop Rajendra

Computer Science and Engineering Theses - Archive

The D0 experiment is one of the two high energy physics experiments currently being conducted at Fermi National Accelerator Laboratory, in Batavia, IL, on what is currently the world's highest energy particle accelerator, the Tevatron. The experiment produces vast amounts of raw data of the order of several hundred terabytes. This data needs to be converted from the raw format that comes from the detector, ie. digitized data, to a format that is close to the physics, ie. data that can be subjected to analysis. This process, called reconstruction, is done according to constantly evolving and improving reconstruction algorithms. This …

Go to article

Structure Based Xml Indexing, Niroj Manandhar Aug 2005

Structure Based Xml Indexing, Niroj Manandhar

Computer Science and Engineering Theses - Archive

The increase in the usage and popularity of semi-structured data has received considerable attention, and a lot of research is going on for the efficient retrieval and storage of semi-structured data. A popular model and language for semi-structured data is XML. In this thesis we focus on the structure based indexing of XML. As a part of an ongoing XML indexing project, we study and implement A(k)-index, which is a structure based indexing technique; and propose the use of offset, length pair to retrieve nodes of interest. We record offset and length of every node using the SAX parser, and …

Go to article

Numerical Simulation Of Pulse Detonation Phenomena In A Parallel Environment, Prashaanth Ravindran Aug 2005

Numerical Simulation Of Pulse Detonation Phenomena In A Parallel Environment, Prashaanth Ravindran

Mechanical and Aerospace Engineering Theses - Archive

The objective of this work was to develop a parallel algorithm that would be used in the simulation of the detonation process in the chamber of a pulse detonation engine. The emphasis is laid on reducing computation time while maintaining the accuracy of the solution and subsequently developing a numerical solution to be in agreement with real-world physical characteristics of a detonation wave initiation, build-up and progression. The flow is assumed to be unsteady, inviscid and non heat conducting. To adhere to real time effects, the flow equations are coupled with finite rate chemistry and the vibrational energy equation are …

Go to article

Environmental Influence On Underage Drinking: An Assessment Of East Dallas, Madeline C. Reedy Aug 2005

Environmental Influence On Underage Drinking: An Assessment Of East Dallas, Madeline C. Reedy

Public Affairs Theses - Archive

With the STOP Underage Drinking Act reintroduced at the national level, policy makers are in the midst of determining how to conquer the issues that arise out of underage drinking. The current project, in conjunction with the Alliance on Undeage Drinking (ALOUD), seeks to provide a picture of one such environment in which underage drinkers live. The current study focused its efforts on providing ALOUD with an environmental assessment of East Dallas. It provided information on alcohol outlets, community resources, schools, and alcohol advertising. The environmental assessment provides ALOUD with the data that it will need to determine which areas …

Go to article

An Approximate Solution To Buckling Of Plates By The Galerkin Method, Yattender Rishi Dubey Aug 2005

An Approximate Solution To Buckling Of Plates By The Galerkin Method, Yattender Rishi Dubey

Mechanical and Aerospace Engineering Theses - Archive

This thesis presents a semi-analytical method to solve the governing differential equation of plates using the Galerkin method. Symbolic algebra software is extensively used to perform necessary calculations. In this thesis, the lateral deflection of a plate is expressed in a series of polynomials each of which satisfies the given homogeneous boundary conditions. The coefficients of these polynomials are found out by the Galerkin method. Symbolic algebra software works best while handling necessary algebra to generate admissible polynomials and build required matrices for solving for the coefficients.This thesis demonstrates the calculation of the lateral load for different plates under different …

Go to article

Environmental Influence On Underage Drinking: An Assessment Of East Dallas, Madeline C. Reedy Aug 2005

Environmental Influence On Underage Drinking: An Assessment Of East Dallas, Madeline C. Reedy

Public Affairs Theses - Archive

With the STOP Underage Drinking Act reintroduced at the national level, policy makers are in the midst of determining how to conquer the issues that arise out of underage drinking. The current project, in conjunction with the Alliance on Undeage Drinking (ALOUD), seeks to provide a picture of one such environment in which underage drinkers live. The current study focused its efforts on providing ALOUD with an environmental assessment of East Dallas. It provided information on alcohol outlets, community resources, schools, and alcohol advertising. The environmental assessment provides ALOUD with the data that it will need to determine which areas …

Go to article

Spreading, Solidification And Remelting Behavior Of Liquid Metal Droplets Sequentially Impinging Onto A Metal Substrate, Lister Manohar Pinto Aug 2005

Spreading, Solidification And Remelting Behavior Of Liquid Metal Droplets Sequentially Impinging Onto A Metal Substrate, Lister Manohar Pinto

Mechanical and Aerospace Engineering Theses - Archive

The fluid dynamics and simultaneous solidification of two successive molten metal droplets impacting a flat substrate is investigated numerically. The primary objective is to investigate the effects of initial droplet and substrate temperature, and the latent heat of substrate material, on the spreading, solidification and remelting of molten tin droplets impacting a substrate of the same material. A robust fluid-flow solver that is capable of modeling rapidly deforming free surfaces involving a moving phase-change boundary is employed in the study. The Navier-Stokes equations are solved using a finite volume formulation. A two-step projection method is used to solve for incompressible …

Go to article

Design Optimization And Synthesis Of Manipulators Based On Various Manipulation Indices, Sandipak Bagchi Aug 2005

Design Optimization And Synthesis Of Manipulators Based On Various Manipulation Indices, Sandipak Bagchi

Mechanical and Aerospace Engineering Theses - Archive

Design optimization of serial manipulators involves striking a balance between an appropriate joint angle and exact link lengths. The optimization technique used in this thesis uses a unique algorithm that optimizes the joint angle through an Inverse Kinematics program. The synthesis problem involves setting up an accurate design length so as to reach a set of given target points inside the workspace without any singularity. The optimization process based on task specification focuses on the maximization of manipulability index, the objective function subjected to link length and joint angle constraints. The results obtained were plotted and animated to visualize the …

Go to article

Piezoelectric Micropump For Drug Delivery Application, Miteshkumar Sureshchandra Joshi Aug 2005

Piezoelectric Micropump For Drug Delivery Application, Miteshkumar Sureshchandra Joshi

Material Science and Engineering Theses - Archive

Bending type actuators providing high displacement (~1mm) with low blocking force (~0.5N) and the stack actuators providing low displacement (~1m) with high blocking force (~1kN) represent the extreme ends of the current piezoelectric actuation technology. In the intermediate range there is deficiency of the actuator designs that provide high displacement with high blocking force in low frequency range of ~2 kHz. This thesis addresses this issue and describes a metal-ceramic actuator design that exhibits high displacement with high blocking force. The structure consist of a piezoelectric bar poled along the length and metal caps were attached to the two opposite …

Go to article

Comparison Of Adsorption Capacities Of Nanoadsorbents With Conventional Activated Carbon For Volatile Organic Compounds, Namrata Baburao Deshmukh Aug 2005

Comparison Of Adsorption Capacities Of Nanoadsorbents With Conventional Activated Carbon For Volatile Organic Compounds, Namrata Baburao Deshmukh

Civil Engineering Theses - Archive

This research explores the potential for using single wall carbon nanohorns (SWNHs) for adsorption of volatile organic compounds (VOCs) categorized as hazardous air pollutants and which contribute to ground level ozone smog formation. It also compares the adsorption capacity of conventional activated carbon and carbon nanohorns. Carbon nanoadsorbents, with at least one dimension on the nanometer scale, can possess advantages over traditional activated carbon adsorbents in terms of binding energies or interaction potentials for physisorption. Nanotubes and nanohorns both have excellent adsorption properties due to high-energy adsorption sites in their interior (internal pores) and in the region between adjacent nanotubes/nanohorns …

Go to article

Field And Experimental Studies To Assess The Performance Of Stabilized Expansive Clay, Gautham S. Pillappa Aug 2005

Field And Experimental Studies To Assess The Performance Of Stabilized Expansive Clay, Gautham S. Pillappa

Civil Engineering Theses - Archive

A vast majority of the expansive soils are montmorillonite-rich clays, over consolidated clays and shales. The swell and shrinkage movements of expansive soil cause considerable damage to structures such as buildings and pavements. This damage can be attributed to moisture fluctuations caused by seasonal variations. Volumetric changes typically appear in the form of cracks which will lead to the softening and vertical heaving in subsoils. Both softening and vertical expansion induce damage to overlying structures. Certain soils rich with sulfates exhibit swell and heaving even after treatment with stabilizers. The present research project was conducted at the University of Texas …

Go to article

Evaluation Of Texas Cone Penetrometer Test To Predict Undrained Shear Strength Of Clays, Hariharan Vasudevan Aug 2005

Evaluation Of Texas Cone Penetrometer Test To Predict Undrained Shear Strength Of Clays, Hariharan Vasudevan

Civil Engineering Theses - Archive

The cone penetration test used in Texas is termed as Texas cone penetrometer (TCP), which works on dynamic principles similar to those of SPT, i.e. a hammer is used to drive the cone device for a preset depth of penetration of 12 inches. Results are typically reported in the form of N12 values. Correlations between N12 and soil strength properties are currently used by the TxDOT to determine in situ strength properties of soils prior to any infrastructure design. A research study was initiated to evaluate the existing shear strength predicting correlations used by TxDOT and its applicability for soils …

Go to article

Water Damage Evaluation Of Concrete Infrastructure, Roshan Shakya Aug 2005

Water Damage Evaluation Of Concrete Infrastructure, Roshan Shakya

Civil Engineering Theses - Archive

This study presents an experimental program to evaluate the effect of a special waterproofing material, International Chem-Crete Pavix (CCP), on the durability of concrete. The experimental program identified the concrete mix design commonly used for pavement and other infrastructure as set by Texas Department of Transportation (TXDOT). The tests conducted include the water absorption and air void (ASTM C 642), freeze-thaw (ASTM C 666), chloride penetration (ASTM C 1202), and petrographic (ASTM C 457) test. The tests were performed on both cored and laboratory treated and untreated specimens. The absorption test was performed on the concrete specimens with water cement …

Go to article

Impacts Of Signal Synchronization On Vehicular Emissions - An On-Board Measurement Case Study, Rupangi Munshi Aug 2005

Impacts Of Signal Synchronization On Vehicular Emissions - An On-Board Measurement Case Study, Rupangi Munshi

Civil Engineering Theses - Archive

Nearly 56% of total nitrogen oxide (NOx) emissions are produced by mobile sources. Transportation and air quality managers at the state and regional level have the responsibility of developing and evaluating Transportation Control Measures (TCMs) and Transportation Improvement Plans (TIPs) to improve air quality of the region. Signal synchronization is considered to be an effective TCM to reduce corridor congestion and maintain air quality in the region. This research was carried to determine the impacts of signal synchronization on real-world, on-road emissions. A portable instrument, OBS-1300 manufactured by Horiba Instruments Inc., was used to measure on-road tailpipe emissions of NOx …

Go to article

Development Of Finite Element Method-Based Model Equations For Hollow Tapered Poles, Jiwon Jung Aug 2005

Development Of Finite Element Method-Based Model Equations For Hollow Tapered Poles, Jiwon Jung

Civil Engineering Dissertations - Archive

This study presents the development of three-parameter load-deflection models for steel and FRP poles commonly used to support closed circuit television cameras. An experimental investigation is carried out to obtain static load-deflection characteristics of tapered octagonal steel cross section and circular FRP cross section poles. Numerical results generated from three-dimensional isoparametric finite element model (FEM) considering coupled nonlinear algorithms for material, geometric, contact, and pre-tensioning effects are compared with those obtained experimentally. Eight-node elsto-plastic solid element is employed to model the pole, end-plate, bolts, concrete base, and laboratory reaction floor. The laboratory reaction floor is modeled with a thick plate …

Go to article

Analysis Of The Dynamics Of Vasomotion Using Laser Doppler Flow, Shruthi Raj Aug 2005

Analysis Of The Dynamics Of Vasomotion Using Laser Doppler Flow, Shruthi Raj

Bioengineering Theses - Archive

Vasomotion is a phenomenon caused by changes in the diameters of blood vessels. It is due to the contractile activity of small arteries and arterioles resulting in periodic changes of blood flow in the skin. These flow variations in the arteries are reflected by the Laser Doppler Flowmeter. The goal of the skin blood flow (blood perfusion) study is to establish a method to analyze and quantify the pattern of vasomotion as detected using Laser Doppler Flow (LDF). Spectral analysis of the LDF signal reveals the presence of periodic components in the vascular system. The study involves twelve subjects of …

Go to article

First Prev Next Last