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Geant4 Physics Processes For Microdosimetry Simulation: Design Foundation And Implementation Of The First Set Of Models, S. Chauvie, Z. Francis, S. Guatelli, S. Incerti, B. Mascialino, P. Moretto, P. Nieminen, Maria Pia Dec 2012

Geant4 Physics Processes For Microdosimetry Simulation: Design Foundation And Implementation Of The First Set Of Models, S. Chauvie, Z. Francis, S. Guatelli, S. Incerti, B. Mascialino, P. Moretto, P. Nieminen, Maria Pia

Susanna Guatelli

New physical processes specific for microdosimetry simulation are under development in the Geant4 Low Energy Electromagnetic package. The first set of models implemented for this purpose cover the interactions of electrons, protons and light ions in liquid water; they address a physics domain relevant to the simulation of radiation effects in biological systems, where water represents an important component. The design developed for effectively handling particle interactions down to a low energy scale and the physics models implemented in the first public release of the software are described.


A Comparison Of X-Ray And Proton Beam Low Energy Secondary Electron Track Structures Using The Low Energy Models Of Geant4, Aimee Mcnamara, Susanna Guatelli, Dale Prokopovich, Mark Reinhard, Anatoly Rosenfeld Dec 2012

A Comparison Of X-Ray And Proton Beam Low Energy Secondary Electron Track Structures Using The Low Energy Models Of Geant4, Aimee Mcnamara, Susanna Guatelli, Dale Prokopovich, Mark Reinhard, Anatoly Rosenfeld

Susanna Guatelli

"Purpose: Lethal cell damage by ionising radiation is generally initiated by the formation of complex strand breaks, resulting from ionisation clusters in the DNA molecule. A better understanding of the effect of the distribution of ionisation clusters within the cell and particularly in regard to DNA segments could be beneficial to radiation therapy treatment planning. Low energy X-rays generate an abundance of low energy electrons similar to that associated with MeV protons. The study and comparison of the track structure of photon and proton beams could permit the substitution of photon microbeams for single cell ion irradiations at proton facilities …