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2002

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Collusive Bidding In The Fcc Spectrum Auctions, Peter Cramton, Jesse Schwartz May 2014

Collusive Bidding In The Fcc Spectrum Auctions, Peter Cramton, Jesse Schwartz

Jesse A. Schwartz

This paper describes the bid signaling that occurred in many of the FCC spectrum auctions. Bidders in these auctions bid on numerous spectrum licenses simultaneously, with bidding remaining open on all licenses until no bidder is willing to raise the bid on any license. Simultaneous open bidding allows bidders to send messages to their rivals, telling them on which licenses to bid and which to avoid. This “code bidding” occurs when one bidder tags the last few digits of its bid with the market number of a related license. We examine how extensively bidders signaled each other with retaliating bids …


Subsets More Likely To Benefit From Surgery Or Prophylactic Cranial Irradiation After Chemoradiation For Localized Non-Small-Cell Lung Cancer, Bruce Keith, Mark Vincent, Larry Stitt, Anna Tomiak, Richard Malthaner, Edward Yu, Pauline Truong, Richard Inculet, Michael Lefcoe, A. Dar, Walter Kocha, Ian Craig Nov 2002

Subsets More Likely To Benefit From Surgery Or Prophylactic Cranial Irradiation After Chemoradiation For Localized Non-Small-Cell Lung Cancer, Bruce Keith, Mark Vincent, Larry Stitt, Anna Tomiak, Richard Malthaner, Edward Yu, Pauline Truong, Richard Inculet, Michael Lefcoe, A. Dar, Walter Kocha, Ian Craig

Edward Yu

After chemoradiation for localized non-small-cell lung cancer, surgery and prophylactic cranial irradiation (PCI) have been used as additional therapies. Less than a third of patients develop brain recurrences, or have local recurrence as their sole initial site of recurrence; these are groups that would benefit from PCI or surgery, respectively. Pretreatment identification of patients more likely to benefit from surgery or PCI would be useful. A retrospective analysis of 80 patients was performed to determine prognostic factors for such patterns of failure. Twenty-nine patients were subsequently selected for surgery in a nonrandomized manner. Seventeen patients had isolated local initial recurrence …


The Existence Of Gender-Specific Promotion Standards In The U.S., Kathy Paulson Gjerde Nov 2002

The Existence Of Gender-Specific Promotion Standards In The U.S., Kathy Paulson Gjerde

Kathy A. Paulson Gjerde

This paper is motivated by the claim that promotion probabilities are lower for women than men. Using data from the 1984 and 1989 National Longitudinal Youth Surveys, this paper tests this claim and two related hypotheses concerning training and ability. It is found that females are less likely to be promoted than males, and females receive less training than males. The relationship between promotion and gender varies across occupations, however, suggesting that the alleged glass ceiling faced by women and other minorities in the workplace is not uniform across all labor markets.

Note: Link is to the article in a …


Western Frontier Or Feudal Society? Metaphors And Perceptions Of Cyberspace, Alfred C. Yen Nov 2002

Western Frontier Or Feudal Society? Metaphors And Perceptions Of Cyberspace, Alfred C. Yen

Alfred C. Yen

The Article examines how metaphors influence perceptions of cyberspace. Among other things, the Article studies the comparison of cyberspace to the American western frontier and the metaphor's construction cyberspace as a "place" whose natural characteristics guarantee freedom and opportunity. This supports an often-made claim that cyberspace is different from real space, and that government should generally refrain from regulating the Internet.

The Article surveys the basis of the western frontier metaphor in academic history and popular culture and concludes that the metaphor misleads people to overestimate cyberspace's "natural" ability to guarantee freedom and opportunity. The Article accomplishes this in part …


A Convenient One-Pot, Organoaluminum Mediated Vinylsilane Synthesis From Non-Enolizable Ketones Via The Peterson Protocol, Man Lung Kwan, Merle Battiste Nov 2002

A Convenient One-Pot, Organoaluminum Mediated Vinylsilane Synthesis From Non-Enolizable Ketones Via The Peterson Protocol, Man Lung Kwan, Merle Battiste

Man Lung Desmond Kwan

Vinylsilanes serve as convenient vinyl anion equivalents which have gained popularity over decades. A variety of non-enolizable aromatic ketones are converted to the corresponding vinylsilanes in a one-pot procedure involving the addition of (trimethylsilylmethyl)lithium to aromatic ketones followed by addition of diethylaluminum chloride and then small amounts of water. Halide and alkoxide substituents are tolerated, and this trans-stereoselective (broad generalization; the most sterically bulky group on the double bond is trans to the trimethylsilyl group) reaction affords vinylsilanes in good yield.


What Is Cochrane All About?, Chris Del Mar, Jenny Doust Oct 2002

What Is Cochrane All About?, Chris Del Mar, Jenny Doust

Jenny Doust

Recently the Australian Minister for Health, the Hon Kay Patterson, announced that Australia is purchasing the Cochrane Library for all Australians. Australians will now have access to the library free of charge through the web.


Syd-1, A Presynaptic Protein With Pdz, C2 And Rhogap-Like Domains, Specifies Axon Identity In C. Elegans, Steven Hallam, Alexandr Goncharov, Jason Mcewen, Renee Baran, Yishi Jin Oct 2002

Syd-1, A Presynaptic Protein With Pdz, C2 And Rhogap-Like Domains, Specifies Axon Identity In C. Elegans, Steven Hallam, Alexandr Goncharov, Jason Mcewen, Renee Baran, Yishi Jin

Renee Baran

Axons are defined by the presence of presynaptic specializations at specific locations. We show here that loss-of-function mutations in the C. elegans gene syd-1 cause presynaptic specializations to form in the dendritic processes of GABA-expressing motor neurons during initial differentiation. At a later developmental stage, however, syd-1 is not required for the polarity respecification of a subset of these neurons. The SYD-1 protein contains PDZ, C2 and rho–GTPase activating protein (GAP)-like domains, and is localized to presynaptic terminals in mature neurons. A truncated SYD-1 that lacks the rhoGAP domain interferes with neurite outgrowth and guidance. Our data indicate that syd-1 …


Patenting Our Lives And Our Genes: Where Does Congress Stand? Public Commet To Ftc Hearing On Competition And Intellectual Property Law And Policy In The Knowledge-Based Economy, Thomas Horton Oct 2002

Patenting Our Lives And Our Genes: Where Does Congress Stand? Public Commet To Ftc Hearing On Competition And Intellectual Property Law And Policy In The Knowledge-Based Economy, Thomas Horton

Thomas J. Horton

No abstract provided.


Hard Code Now!, Ugo Mattei Oct 2002

Hard Code Now!, Ugo Mattei

Ugo Mattei

This paper advocates the immediate beginning of a genuine, pluralistic political process leading to a binding codification of European Private Law. It is a critique of what I characterize as the post-modernist "soft" discourse of current European private law. This soft ideology stays behind proposals of "restatement" of European law; notions of "model" European codes; assertions of the sufficiency of European legal science as an alternative to codification; theories of competition between national legal systems as an efficient pattern of private law integration; notions of facilitating, optional "default law" as an efficient alternative to mandatory binding legal rules. My claim …


Asymptotic Solitons For A Higher-Order Modified Korteweg–De Vries Equation, T. Marchant Oct 2002

Asymptotic Solitons For A Higher-Order Modified Korteweg–De Vries Equation, T. Marchant

Tim Marchant

Solitary wave interaction for a higher-order modified Korteweg–de Vries (mKdV) equation is examined. The higher-order mKdV equation can be asymptotically transformed to the mKdV equation, if the higher-order coefficients satisfy a certain algebraic relationship. The transformation is used to derive the higher-order two-soliton solution and it is shown that the interaction is asymptotically elastic. Moreover, the higher-order phase shifts are derived using the asymptotic theory. Numerical simulations of the interaction of two higher-order solitary waves are also performed. Two examples are considered, one satisfies the algebraic relationship derived from the asymptotic theory, and the other does not. For the example …


An Evaluation Of College And Low Income Youth Writing Together: Self Discovery And Cultural Connection, Genevieve Chandler Sep 2002

An Evaluation Of College And Low Income Youth Writing Together: Self Discovery And Cultural Connection, Genevieve Chandler

Genevieve E. Chandler

Although the health and healing effects of writing have been documented in the literature, most of the studies have focused primarily on individuals writing alone. This formative evaluation is a component of an intervention reported elsewhere. The evaluation describes the experience of low-income youth and college students ( n = 7) writing in a group during a 10-week workshop. The results revealed the development of protective processes of self-esteem, self-efficacy, coping strategies, social support, and cultural connections. In the weekly 2-hr writing sessions, using the Amherst Writers and Artists method, participants were encouraged to write their stories in their own …


Retinal Histopathology Of An Xlrp Carrier With A Mutation In The Rpgr Exon Orf15, Gustavo Aguirre, Beverly Yashar, Sinoj John, Julie Smith, K Breuer, S Hiriyanna, Anand Swaroop, Ann Milam Sep 2002

Retinal Histopathology Of An Xlrp Carrier With A Mutation In The Rpgr Exon Orf15, Gustavo Aguirre, Beverly Yashar, Sinoj John, Julie Smith, K Breuer, S Hiriyanna, Anand Swaroop, Ann Milam

Gustavo D. Aguirre, VMD, PhD

X-linked retinitis pigmentosa comprises the severe forms of RP, with early onset of night blindness, rapid constriction of visual fields and eventual loss of central acuity. Of the five distinct XLRP loci identified on the X chromosome, mutations have been found only in theRP2 and RPGR genes. Of these, mutations in RPGR are more common, particularly in a mutational hot spot that was identified in the newly discovered exon ORF15. We report on an extended family with a microdeletion in RPGR exon ORF15 and the retinalhistopathology of a female carrier of this mutation. We found a 1 bp …


Encapsulated Cell-Based Delivery Of Cntf Reduces Photoreceptor Degeneration In Animal Models Of Retinitis Pigmentosa, Weng Tao, Rong Wen, Moses B. Goddard, Sandy D. Sherman, Pam J. O'Rourke, Paul F. Stabila, William J. Bell, Brenda J. Dean, Konrad A. Kauper, Veronica A. Budz, William G. Tsiaras, Gregory M. Acland, Sue Pearce-Kelling, Alan Laties, Gustavo D. Aguirre Sep 2002

Encapsulated Cell-Based Delivery Of Cntf Reduces Photoreceptor Degeneration In Animal Models Of Retinitis Pigmentosa, Weng Tao, Rong Wen, Moses B. Goddard, Sandy D. Sherman, Pam J. O'Rourke, Paul F. Stabila, William J. Bell, Brenda J. Dean, Konrad A. Kauper, Veronica A. Budz, William G. Tsiaras, Gregory M. Acland, Sue Pearce-Kelling, Alan Laties, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

Purpose: The objective of the present study was to evaluate the therapeutic efficacy of ciliary neurotrophic factor (CNTF) delivered through encapsulated cells directly into the vitreous of the eye in an rcd1 canine model of retinitis pigmentosa. The dose–range effect of the treatment was also investigated.
Methods: Polymer membrane capsules (1.0 cm in length and 1.0 mm in diameter) were loaded with mammalian cells that were genetically engineered to secrete CNTF. The cell-containing capsules were then surgically implanted into the vitreous of one eye of rcd1 dogs at 7 weeks of age, when retinal degeneration is in progress but not complete. The …


Pseudomonas Aeruginosa Elastase Stimulates Erk Signaling Pathway And Enhances Il- 8 Production By Alveolar Epithelial Cells In Culture, Ali Azghani, J. W. Baker, S. Shetty, E. J. Miller, G. J. Bhat Sep 2002

Pseudomonas Aeruginosa Elastase Stimulates Erk Signaling Pathway And Enhances Il- 8 Production By Alveolar Epithelial Cells In Culture, Ali Azghani, J. W. Baker, S. Shetty, E. J. Miller, G. J. Bhat

Ali Azghani

Objective and design: Bacterial products as well as the host airway inflammatory responses contribute to the pathogenesis of Pseudomonas infections. We sought to determine if Pseudomonas elastase (PE) induces mitogen-activated protein (MAP) kinase activity in association with interleukin-8 (IL-8) production by alveolar epithelial cells.¶Methods: We utilized Western blot analysis to detect phosphorylation of signaling intermediates and ELISA was used to measure IL-8 production.¶Results: We found that PE induces phosphorylation of the extracellular signal-regulated (ERK1/2) proteins of the MAPK pathway in A549 epithelial cells. Similar results were obtained using primary cultures of rabbit alveolar type II epithelial cells. PE also enhanced …


Placebo Tribulations, Charles Weijer Sep 2002

Placebo Tribulations, Charles Weijer

Charles Weijer

No abstract provided.


Ultrafast Measurement Of Two-Photon Absorption By Loss Modulation, Peifang Tian, Warren Warren Aug 2002

Ultrafast Measurement Of Two-Photon Absorption By Loss Modulation, Peifang Tian, Warren Warren

Peifang Tian

We demonstrate a direct and sensitive technique for measuring two-photon absorption (TPA).An intensity- modulated femtosecond laser beam passes through a sample exhibiting TPA.A TPA signal at twice the modulation frequency is then generated and subsequently measured by a lock-in amplifier. The absolute TPA cross section of Rhodamine 6G at 800nm is found to be 15.32.010 -50 cm 4 s / photon and agrees well with previously published results obtained with much higher intensity [J.Chem.Phys. 112, 9201 (2000)]. Our method may be especially useful in measuring nonlinear absorptions of nonfluorescent materials.


Sensory Processing Correlates Of Occupational Performance In Children With Fragile X Syndrome: Preliminary Findings, Grace T. Baranek, Yuki H. Chin, Laura Greiss Hess, Jann G. Yankee, Deborah D. Hatton, Stephen R. Hooper Aug 2002

Sensory Processing Correlates Of Occupational Performance In Children With Fragile X Syndrome: Preliminary Findings, Grace T. Baranek, Yuki H. Chin, Laura Greiss Hess, Jann G. Yankee, Deborah D. Hatton, Stephen R. Hooper

Laura Greiss Hess

OBJECTIVES. This preliminary study examined sensory processing and its relationship to occupational performance in children with fragile X syndrome (FXS) to guide research and evidence-based practice.

METHOD. Fifteen school-aged boys with full-mutation FXS were assessed with three occupational performance measures (School Function Assessment, Vineland Adaptive Behavior Scales, play duration) and three sensory processing measures (Sensory Profile, Tactile Defensiveness and Discrimination Test–Revised, Sensory Approach–Avoidance Rating). Data were analyzed using partial correlation procedures.

RESULTS. Several significant correlations were found, independent of effects of age and IQ. Avoidance of sensory experiences (internally controlled) was associated with lower levels of school participation, self-care, and …


Matters Of Life And Death: Making Moral Theory Work In Medical Ethics And The Law, James Anderson, Charles Weijer Aug 2002

Matters Of Life And Death: Making Moral Theory Work In Medical Ethics And The Law, James Anderson, Charles Weijer

Charles Weijer

No abstract provided.


Infrared Depletion Spectroscopy Of Aniline-Acetonitrile Cation And Aniline-Acetonitrile-Water Cation Clusters, H. Nagai, Naveed Piracha, T. Nakanaga Aug 2002

Infrared Depletion Spectroscopy Of Aniline-Acetonitrile Cation And Aniline-Acetonitrile-Water Cation Clusters, H. Nagai, Naveed Piracha, T. Nakanaga

Naveed K. Piracha

The vibrational spectra of the aniline-acetonitrile^+ and the aniline-acetonitrile-water^+ cluster cations have been measured by the infrared depletion spectroscopy in the frequency region of NH and OH stretching vibrations. One absorption band was observed at 3437cm^-^1 in the infrared spectrum of the aniline-acetonitrile^+ cluster cation, and was assigned to the NH stretching vibration of free NH of aniline. As for the aniline-water-acetonitrile^+ cluster cation, three absorptions were observed at 3722, 3634 and 3247cm^-^1, which were assigned to the anti-symmetric stretching and symmetric stretching vibrations of OH of water and the stretching vibrations of NH bond interacting with water, respectively. In …


An Investigation Of Personal Learning In Mentoring Relationships: Content, Antecedents, And Consequences, Terri Scandura, Melanie Lankau Jul 2002

An Investigation Of Personal Learning In Mentoring Relationships: Content, Antecedents, And Consequences, Terri Scandura, Melanie Lankau

Terri A. Scandura

No abstract provided.


'...The Times They Are A-Changin': Political Protests—Iowa State University—May 1970, A Photographic Essay And Oral History, Gerry Mckiernan, Michele Christian Jul 2002

'...The Times They Are A-Changin': Political Protests—Iowa State University—May 1970, A Photographic Essay And Oral History, Gerry Mckiernan, Michele Christian

Michele Christian

In early May 1970, thousands of Iowa State University students gathered to protest the expanding war in Vietnam and Southeast Asia and the killing of four unarmed students on the campus of Kent State University. This photographic essay seeks to document significant events of the first week in May 1970 on the ISU campus and in Ames, Iowa, utilizing photographs selected from the archives of the Iowa State University Library, Special Collections Department, excerpts of reports from the university newspaper, the Iowa State Daily, and summaries from a chronological account of these and other events presented in a masters thesis …


Law, Science, And Science Studies: Contrasting The Deposition Of A Scientific Expert With Ethnographic Studies Of Scientific Practice, David Caudill Jul 2002

Law, Science, And Science Studies: Contrasting The Deposition Of A Scientific Expert With Ethnographic Studies Of Scientific Practice, David Caudill

David S Caudill

No abstract provided.


Electrical Conductivity And Thermopower Of Cu–Sio[Sub 2] Nanogranular Films., W. Chen, J. Lin, X. Zhang, H. Shin, Jeffrey Dyck, C. Uher Jul 2002

Electrical Conductivity And Thermopower Of Cu–Sio[Sub 2] Nanogranular Films., W. Chen, J. Lin, X. Zhang, H. Shin, Jeffrey Dyck, C. Uher

Jeffrey Dyck

We have measured the thermopower S and electrical conductivity σ in a series of Cu[sub x](SiO[sub 2])[sub 1-x] nanogranular films between 2 and 300 K with Cu volume fraction x varying from 0.43 up to 1.0. At low temperatures, disorder-enhanced electron-electron interaction effects dictate the behavior of σ. A crossover of the temperature dependence from σ∝ √T to σ∝ T[sup 1/3] is observed as x is lowered and the metal-insulator transition is approached. S is small, shows linear temperature dependence, and is rather insensitive to the change of x. Effects of annealing are also discussed.


Sds-Page And Western Blotting Of Plasmodium Falciparum Proteins, Roland A. Cooper Jun 2002

Sds-Page And Western Blotting Of Plasmodium Falciparum Proteins, Roland A. Cooper

Roland A. Cooper

The Plasmodium spp. parasite was identified as the causative agent of malaria in 1880, and the mosquito was identified as the vector in 1897. Despite subsequent efforts focused on the epidemiology, cell biology, immunology, molecular biology, and clinical manifestations of malaria and the Plasmodium parasite, there is still no licensed vaccine for the prevention of malaria. Physical barriers (bed nets, window screens) and chemical prevention methods (insecticides and mosquito repellents) intended to interfere with the transmission of the disease are not highly effective, and the profile of resistance of the parasite to chemoprophylactic and chemotherapeutic agents is increasing. The dawn …


Characterizing Gene Expression During Lens Formation In Xenopus Laevis: Evaluating The Model For Embryonic Lens Induction, Brian Walter, Jonathan Henry, Maria Carinato, Jonathan Schaefer, Adam Wolfe, Brian Walter, Kimberly Perry, Tricia Elbl May 2002

Characterizing Gene Expression During Lens Formation In Xenopus Laevis: Evaluating The Model For Embryonic Lens Induction, Brian Walter, Jonathan Henry, Maria Carinato, Jonathan Schaefer, Adam Wolfe, Brian Walter, Kimberly Perry, Tricia Elbl

Brian Walter

Few directed searches have been undertaken to identify the genes involved in vertebrate lens formation. In the frog Xenopus, the larval cornea can undergo a process of transdifferentiation to form a new lens once the original lens is removed. Based on preliminary evidence, we have shown that this process shares many elements of a common molecular/genetic pathway to that involved in embryonic lens development. A subtracted cDNA library, enriched for genes expressed during cornea-lens transdifferentiation, was prepared. The similarities/identities of specific clones isolated from the subtracted cDNA library define an expression profile of cells undergoing cornea-lens transdifferentiation ("lens regeneration") and …


Continuing Review Of Clinical Research Canadian-Style, Charles Weijer May 2002

Continuing Review Of Clinical Research Canadian-Style, Charles Weijer

Charles Weijer

No abstract provided.


Follow The Market's Cues, Peter Navarro Apr 2002

Follow The Market's Cues, Peter Navarro

PETER NAVARRO

No abstract provided.


Lessons From Everyday Lives: A Moral Justification For Acute Care Research, Andrew Mcrae, Charles Weijer Apr 2002

Lessons From Everyday Lives: A Moral Justification For Acute Care Research, Andrew Mcrae, Charles Weijer

Charles Weijer

Progress in emergency and critical care requires that clinical research be performed on patients who are incapable of granting consent for research participation. Analyses of the ethics of such research have left some questions incompletely answered. Why should we be permitted to expose vulnerable patients to research risks without their consent? In particular, how do we justify research interventions that have no potential benefit for participants (nontherapeutic interventions)? This article presents a moral justification for nontherapeutic interventions in emergency research. By relying on a framework for assessing research risks, and by drawing on the example of pediatric research, this justification …


The Biophysics Of Leaf Growth In Salt-Stressed Barley. A Study At The Cell Level., Wieland Fricke, Winfried Peters Apr 2002

The Biophysics Of Leaf Growth In Salt-Stressed Barley. A Study At The Cell Level., Wieland Fricke, Winfried Peters

Winfried S. Peters

Biophysical parameters potentially involved in growth regulation were studied at the single-cell level in the third leaf of barley (Hordeum vulgare) after exposure to various degrees of NaCl stress for 3 to 5 d. Gradients of elongation growth were measured, and turgor pressure, osmolality, and water potentials (ψ) were determined (pressure probe and picoliter osmometry) in epidermal cells of the elongation zone and the mature blade. Cells in the elongation zone adjusted to decreasing external ψ through increases in cell osmolality that were accomplished by increased solute loads and reduced water contents. Cell turgor changed only slightly. In …


Walt Whitman: Poet And Nurse, William Ahrens Apr 2002

Walt Whitman: Poet And Nurse, William Ahrens

William D. Ahrens

Comments on the life of Walt Whitman, American poet and a nurse by profession. Composition of poems on health, fitness and exercise; Services to the wounded soldiers during the Civil War; Recognition of the disease and infection inflicted on soldiers.