Digital Commons Network^™

Attenuation Of Traumatic Brain Injury-Induced Cognitive Impairment In Mice By Targeting Increased Cytokine Levels With A Small Molecule Experimental Therapeutic, Adam D. Bachstetter, Scott J. Webster, Danielle S. Goulding, Jonathan E. Morton, D. Martin Watterson, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Evidence from clinical studies and preclinical animal models suggests that proinflammatory cytokine overproduction is a potential driving force for pathology progression in traumatic brain injury (TBI). This raises the possibility that selective targeting of the overactive cytokine response, a component of the neuroinflammation that contributes to neuronal dysfunction, may be a useful therapeutic approach. MW151 is a CNS-penetrant, small molecule experimental therapeutic that selectively restores injury- or disease-induced overproduction of proinflammatory cytokines towards homeostasis. We previously reported that MW151 administered post-injury (p.i.) is efficacious in a closed head injury (CHI) model of diffuse TBI in mice. Here we test …

Identifying Genes Involved In Suppression Of Tumor Formation In The Planarian Schmidtea Mediterranea, Erin Dorsten

Best Integrated Writing

Erin Dorsten makes a proposal for a scientific study of experiments to identify genes involved in protecting an organism with negligible senescence from tumor formation in this piece written for the Integrated Writing course BIO 4020: Current Literature: Biology of Regeneration, taught by Labib Rouhana at Wright State University.

The Making Of Rurality In Hong Kong : Villagers' Changing Perception Of Rural Space, Chun On Lai

Lingnan Theses

The study focus on the ongoing disputes over rural development bring to the fore the competing paradigms and representations of rurality on the part of different rural stakeholders in the New Territories. This study attempt to debunk the conventional image of the rural as a natural, homogenous locality pitted against the urban way of life. Drawing from the qualitative study of twenty-five people who live or often participate in rural activities, the New Territories was an actual space with three co-existing mindsets from three modes of social organization: agricultural, capitalist, post-industrial. These three co-existing mindsets are normally found in many …

Empowerment Through Transformations In Agency-Influence Of Self Help Groups On Women's Empowerment In Rural Nepal, Shikshya Adhikari

Theses and Dissertations

Self-help groups have been considered a powerful tool in empowering women because of the various opportunities they provide women. Self-help groups have started becoming very popular in rural Nepal. My research focuses on the interpretations of men and women in rural Nepal regarding how self-help groups have influenced women's lives. Interviews with women and their husbands reveal that self-help groups have provided women with physical social mobility, increased knowledge and skills, increased their ability to speak and voice opinions, and increased their capacity to invest in their children's education. However, women have not been able to earn money through independent …

Interfacing Catholic Social Meanings, Sociology, Self, And Pedagogical Practices, Daniel J. Myers, Andrew J. Weigert

Engaging Pedagogies in Catholic Higher Education (EPiCHE)

What connects Catholic Social Tradition with Sociology? How do each inform the other and how do they, together, flow through and animate the sociologist? Within a student-driven learning community pedagogy, this course builds on the humanistic aspects of Sociology as a scientific perspective a la Peter Berger’s Invitation to Sociology. This foundation is then filtered through a social psychological understanding of self with a sense of vocation through which persons’ deepest passions meets humans’ greatest needs. Biographical vignettes of sociologists’ careers of study that address issues of racial and gender inequalities and psycho-social shifts in values over the life course …

Journey Into Shame: Implications For Justice Pedagogies, Roger C. Bergman

Engaging Pedagogies in Catholic Higher Education (EPiCHE)

Being formed for justice can be a painful experience. Sometimes that pain takes the form of shame and contributes to the formation and exercise of conscience. But shame in other forms can be opposed to human flourishing and social justice. Psychologist James Fowler provides a spectrum of two forms of healthy shame and four forms of unhealthy shame, to which the author adds four other varieties, strategic shame and spiritual shame, at one end of the spectrum, and murderous shame and genocidal shame, at the other. Various experiences of shame are dramatically illustrated in Black Like Me, John Howard …

A Behavioral Analysis Of The Pre-Release Tasmanian Devils (Sarcophilus Harrisii) Currently At Devils@Cradle: An Assessment Of The Impacts Of Captivity On The Wild Behaviors Of Tasmanian Devils That Are Important For Their Reintroduction, Survival, And Inclusion In Wild Populations, Anna Staudenmaier

Independent Study Project (ISP) Collection

The Tasmanian devil, Sarcophilus harrisi, is in danger of extinction in the wild due to the emergence of Devil Facial Tumor Disease (DFTD). In an attempt to save the species the Save the Tasmanian Devil Program (STTDP) has initiated the creation of an ‘Insurance Population’. These insurance animals are a part of the captive breeding population (CBP) designed to conserve the genetic diversity of the species to preserve their ecological function for their future reintroduction into the wild. CBPs are located at various bio-secure zoos, wildlife parks, free-range enclosures (FREs), Tasmanian islands and peninsulas and sanctuaries like Devils@Cradle - Tasmanian …

Magnetic Island Marine Park Zones: Effects Of Fishing Restrictions On Predatory Reef Fish Populations, Casey Wilson

Independent Study Project (ISP) Collection

Over the past several decades industrialized fishing practices have decimated fish stocks worldwide. Top-down trophic cascades have occurred within many marine ecosystems as top predators are removed. Numerous regions world wide are being designated as marine park “no-take” zones in order to aid in the recovery of these species and with the hope that surplus population will spillover into unprotected zones..

This study aimed to determine if there were significant differences in abundances of three major families of predatory reef fish (Serranidae, Lutjanidae, and Lethrinidae) between fringing reefs located in four bays of various zones around Magnetic Island, QLD. Data …

Whom Do You Trust? Doubt And Conspiracy Theories In The 2009 Influenza Pandemic, Shawn C. Smallman Ph.D.

Journal of International and Global Studies

The 2009 pandemic of H1N1 influenza led people around the globe to create narratives about the epidemic defined by the question of trust; these narratives ranged from true conspiracy theories to simply accounts in which mistrust and betrayal formed a motif. In particular, most of these narratives reflected a fear of capitalism and globalization, although in specific regions, other issues—such as religion—played a more central role. These stories were not unique to the H1N1 pandemic but rather have appeared with every contemporary outbreak of infectious disease. This paper will examine conspiracy theories and moral panics related to the H1N1 pandemic …

Traditional Ecological Knowledge And Sustainable Food Sourcing: Dayutang Village, Hani Rice Terraces, Nina Whittaker

Independent Study Project (ISP) Collection

Reflecting on the importance of dynamic agricultural management techniques in addressing climate change and food security, this paper examines the Hani rice terraces of southern Yunnan as a Globally Important Agricultural Heritage System (GIAHS). It identifies local inhabitants’ traditional ecological knowledge (TEK) as a key source of their success, and uses research conducted in Dayutang Village, Yuanyang County from May 4- June 2, 2015 through participative observation and guided conversation to explore the role of Hani TEK in sustainable food sourcing around the village. The TEK used in food sourcing in Dayutang is shown not only to provide villagers with …

Ouch, That Hurts: Childbirth-Related Pain Management And The Inappropriate Replacement Of Traditional Obstetrical Knowledge In Kumaon, Uttarakhand, India, Sabrina Zionts

Independent Study Project (ISP) Collection

Throughout India, obstetrical knowledge and practice has been developed and passed down by generations of women. In many Indian societies, traditional birth attendants, or dais, remain the gatekeepers of childbirth-related knowledge. Yet with the push towards institutional delivery, traditional knowledge and practices are being increasingly replaced with modern and Western ones. While the trend of hospital deliveries has yielded positive health outcomes, its socio-cultural consequences remain unclear. Situated in Uttarakhand’s Kumaon Himalayas, this study employs a bio-social framework and begins to reveal these consequences. Using labor pain management as an entry point, this study argues that the push towards institutional …

Ulaanbaatar’S Ger District Issues: Changes And Attitudes, David Engel

Independent Study Project (ISP) Collection

Several of Ulaanbaatar’s current issues are directly related to Ulaanbaatar’s sprawling Ger District. The Ger District is home to approximately 736,000 residents, 61% of Ulaanbaatar’s population (Galimbyek, 2015). The significant growth in Ulaanbaatar is shown by its 52.8% of residents who were born outside of the city, the majority of migrants moving into the Ger District due to a lack of housing. (Chilkhaasuren & Baasankhuu, 2012). The development of Ulaanbaatar has not kept up with the rapid growth leading to inadequate infrastructure in much of the Ger District. In turn, inadequate infrastructure has lead to high pollution levels, negatively affecting …

Marine Animalia Organism Diversity And Reef Condition On Two Reef Sites At Big Creek Beach And Boca Del Drago, Bocas Del Toro, Panamá, Bri Tiffany

Independent Study Project (ISP) Collection

Ocean acidification, climate change, overfishing, and coastal development are endangering coral reefs across the globe. In Bocas del Toro, Panamá, coral reefs are especially threatened by the rapid growth in tourism and the subsequent anthropogenic effects caused by an increased human presence. To evaluate reef condition in this area, a study comparing percent coverage of live and dead coral as well as the diversity of marine Animalia organisms was conducted at one reef site in Big Creek beach and one reef site in Boca del Drago, Isla Colón, Bocas del Toro. It was predicted that dead coral cover would be …

Comparing Avian Diversity And Anthropogenic Disturbance At Sendero Los Quetzales Cerro Punta, Panamá, Sloane Merdinger

Independent Study Project (ISP) Collection

This report summarizes the survey of land and avian diversity along a transect that runs from the exterior to the interior of the Los Quetzales Trail of Parque Nacional Volcán Barú in Cerro Punta, Chiriquí, Panamá. The region of Cerro Punta is Panamá’s primary producer of produce and also home to one of the most biodiverse land reserves in the world. Despite protection efforts the area is continuously threatened by human development. The study juxtaposes calculated Shannon-Wiener Biodiversity Indices across graduated levels of anthropogenic disturbance to determine if there is a significant difference in biodiversity between areas with low, intermediate, …

The Impact Of Vaccine Hesitancy On The Polio Vaccine In South Asia, Leah Everist

Independent Study Project (ISP) Collection

A disease that paralyzes hundreds of children each year, polio is incurable but also entirely preventable through vaccination. Though part of the reason some children are not reached for immunization is that they are in areas too volatile for healthcare workers to access, vaccine hesitancy is increasingly being recognized as an important player. The objective of this study is to ascertain the degree to which vaccine hesitancy affects polio vaccine campaigns in Afghanistan and Pakistan, the countries in South Asia where polio continues to be endemic, to assess the drivers behind hesitancy in this region, and to present recommendations for …

Volume 07, Rachel C. Lombardi, Ben Osterhout, Lindsay Graybill, Rebecca E. Dey, Skyler T. Carpenter, Emma Beckett, Jason Ware, Mollie Andrews, James Bates, Landon Cooper, Tiffani Jeffries, Maria Wheaton, Dallas Price, Laura Kahler, Sarah Charlton, Anna Bultrowicz, Emily Spittle, Erin Godwin, Eamon Brokenbrough

Incite: The Journal of Undergraduate Scholarship

Introduction from Interim Dean Dr. Jennifer Apperson

Spatial Analysis of Potential Risk Factors Associated with Addition of Atlantic Coast Pipeline Through Virginia by Rachel C. Lombardi

"Delicate Matters with No Speaking," "Hope and Nothing," "Mono Duality" by Ben Osterhout

"Connect" Graphic Design Senior Project by Lindsay Graybill

Phenolic Acids in Brassicaceae Plants: Ovipositional Stimulants or Deterrents for Cabbage White Butterfly, Pieris Rapae? by Rebecca E. Dey And Skyler T. Carpenter

"Abecedarian Cards" by Emma Beckett, Jason Ware, And Mollie Andrews

Helvetica: A Type Specimen Book by James Bates, Landon Cooper, Tiffani Jeffries, And Maria Wheaton

“Things Left Behind” by Dallas …

Affect And Online Privacy Concerns, David Charles Castano

CCAC Theses and Dissertations

The purpose of this study was to investigate the influence of affect on privacy concerns and privacy behaviors. A considerable amount of research in the information systems field argues that privacy concerns, usually conceptualized as an evaluation of privacy risks, influence privacy behaviors. However, recent theoretical work shows that affect, a pre-cognitive evaluation, has a significant effect on preferences and choices in risky situations. Affect is contrasted with cognitive issues in privacy decision making and the role of affective versus cognitive-consequentialist factors is reviewed in privacy context.

A causal model was developed to address how affect influences privacy concerns and …

Investigating Sex Positivity: Does Education And Socialization Increase Sexual Satisfaction In Young Adults, Kendall Coffman

Undergraduate Distinction Papers

Abstract

This study was designed to investigate a proposed association between exposure to sexual education, positive information, and materials, and an individual’s level of comfort, sexual satisfaction, and willingness to discuss sexual topics. This study also looked at the influence of various other variables such as gender, sexual orientation, and relationship status. Undergraduates at a small, private Midwestern college were surveyed with questions regarding the context in which they were exposed to various sexual topics as well as their current levels of sexual satisfaction and willingness to discuss sexual material with a friend, family member, intimate partner, or a stranger. …

Rural China In Transition: Changes And Transformations In China’S Agriculture And Rural Sector, John A. Donaldson, Forrest Q. Zhang

Research Collection School of Social Sciences

Agribusiness companies operating in China are transacting in various forms with small agricultural producers, and in doing so, transforming the household-based agriculture in rural China. We argue that the presence of these distinct forms and the diverging relations between agribusiness and producers show the central importance of China’s collective land rights. China’s unique system of land rights – featuring collective ownership but individualized usage rights – has acted as a powerful force in shaping interactions between agribusiness and direct producers. It provides farmers a source of economic income as well as political bargaining power – albeit to various degrees – …

Assessing Reconstruction: Did The South Undergo Revolutionary Change?, Lauren H. Sobotka

Student Publications

With the end of the Civil War, came a number of unanswered questions Reconstruction would attempt to answer for the South. While the South underwent economic, political and social changes for a short period, old traditions continued to persist resulting in racist sentiment.

Soil Total Organic Carbon And Farmers’ Perceptions Associated With Bokashi Application In Cerro Punta, Panama, Emma Searson

Independent Study Project (ISP) Collection

Sustainable use and maintenance of agricultural soils are important for maintaining long-term agricultural productivity and environmental quality. These issues are especially important in Cerro Punta, known as the breadbasket of Panama, which is experiencing severe erosion. While current practices and agrochemical usage damage soil health and function over time, application of organic material improves soil physic-chemical properties such as nutrient and total organic carbon (TOC) content. Bokashi, a fermented organic soil amendment with effective microorganisms (EM), is thought to be especially beneficial due to its ability to augment populations of soil microbes, which deliver plant-available nutrients to crops and improve …

Women’S Work In A Rural Village: Realities, Motivations, And Satisfaction, Sierra Larson

Independent Study Project (ISP) Collection

According to a United Nations report published in 2004, the remaining key challenge to women’s empowerment and gender equality is “women’s indifference to their own empowerment." [1] Initially I was interested in conducting my fieldwork on the state of women’s satisfaction with women’s rights and gender equality in Indonesia, as well as limits to greater equality. Before beginning my study, I spent time considering this declaration about women’s indifference as a potential barrier to greater empowerment and equality, as well as the biases inherent in the statement. I decided to not focus directly on women’s satisfaction with gender equality, since …

Kenya’S Konza Techno City: Utopian Vision Meets Social Reality, Amina Johari

Independent Study Project (ISP) Collection

This paper explores Kenya’s ambitious Konza Technology City. In 2008 the Kenyan government unveiled its plan to construct a city from scratch 60 kilometers outside of the nation’s capital, Nairobi. Konza Technology City is a flagship project for Kenya Vision 2030, the country’s development program covering the period 2008 to 2030. The new city is expected to relieve Nairobi of some of its traffic and overcrowding issues, and also support the country’s growing technology sector. Konza City is just one of many proposed city plans all over sub-Saharan Africa reflecting a growing phenomenon. Due to the challenges many African cities …

Waste Management And Environmental Initiatives In Accra, Ghana, Aoife Genevieve Duna

Independent Study Project (ISP) Collection

Title: Waste Management and Environmental Initiatives in Accra, Ghana

Author: Aoife Genevieve Duna ([email protected]; Middlebury College, Anthropology and Dance major)

Objective: The objective of this project was fourfold: • To study the current waste management practices by government and private waste companies • To observe the perspectives of residents on waste disposal • To explore environmental initiatives by citizens, NGOs, and student groups • To investigate the potential projects that could reduce waste

Methodology: For my project, I conducted interviews, made observations, participated in daily personal waste management, visited a landfill, and visited a composting project.

Findings: Waste collection is …

Tracking The Elephant (Lexodonta Africana) Corridor And The Human-Wildlife Conflict In Selela Village, Nicole Chlebek, Laura Stalter

Independent Study Project (ISP) Collection

The beastly journey of long-distance migration for the African Elephant (Lexodonta Africana) is important for upholding their connections between diminishing protected areas, especially in northeastern Tanzania. However, human development is encroaching into these corridors, creating a human-elephant conflict, which can ruin livelihoods of villagers, depending on the extent of conflict. This study focused on exploring the hypothesized human-elephant conflict on the Selela corridor, specifically in Selela village, as well as GPS (Global Positioning System) mapping evidence of elephant travel along the projected Selela elephant corridor connecting Ngorongoro Conservation Area (NCA), to Selela Forest Reserve (SFR), and finally to Manyara Ranch. …

The Pelagic Artisanal Fishing Of Mangapwani, Northern Unguja, Shavonne Stanek

Independent Study Project (ISP) Collection

A total of 99 interviews were conducted. Over a period of 28 days from April 5- May 2, 2015, a total of 75 interviews were conducted with 72 fishermen, 2 drying processors and 1 Bwana Diko. During a 5 day preliminary period from March 12-16, 2015, a total of 24 interviews were conducted with 7 fishermen and 14 drying processors. The interviews focused on their work in the local fishing industry, the amount of fish caught and dried, and their opinions on the sustainability of their industry. The interviews were conducted using a translator who relayed the responses in English …

Fauna Census Of Intertidal Cliffs, Mangapwani, Zanzibar, Emily Jankowski

Independent Study Project (ISP) Collection

Due to their extreme variations in condition over the course of a day, intertidal zones are challenging environments. Organisms that live there must be prepared to cope with both exposure and submersion, not to mention the temperature variations that accompany these conditions. The differing tolerances and adaptations of various organisms to these conditions generally cause patterns of vertical zonation to occur in the intertidal zone, especially when the shore is steep and rocky. Understanding the ecology of shore environments is important to future conservation and management efforts. This study was conducted on a beach in Mangapwani, Zanzibar at at 6˚ …

Analysis Of Traditional Medicine In Zanzibar, Tanzania, Jessica Baylor

Independent Study Project (ISP) Collection

Traditional medicine is used as a major source of health care in developing countries. A small island off the coast of Tanzania, Zanzibar has traditional medicine embedded in its culture. Informal interviews of community members and healers in four different villages as well as interviews with the Department of Forestry and the Traditional and Alternative Medicine Unit were conducted over a four week study. This study found that community members of four villages in Zanzibar supported the idea of a regulation of traditional medicine by the government. It also found that the majority of traditional medicine users have noticed a …

The Industrial Impact On Wetlands In Jinja And The Nexus Of Industry, Wetlands, And Community (A Rights-Based Sustainable Development Approach), Ranger Ruffins

Independent Study Project (ISP) Collection

Uganda is a beautiful country filled with an extensive amount of natural resources, one of the most profound being wetlands. It is said that these wetlands are a crucial source of food and water for almost 3 million people (NEMA, 2012 and Oguttu et.al, 2008). They also provide many more invaluable socioeconomic benefits for the country. As Uganda experiences increasing development as well as a rapidly increasing population, the wetlands become increasingly necessary, at the same time they become increasingly threatened. It is written in the 1995 Ugandan constitution that Ugandan policy is aimed at ensuring sustainable development for the …

Non-Compliance In Marine Reserves: Measuring The Drivers Of Behavior Among Recreational Fishermen Within The Great Barrier Reef Marine Park, Nick Manning

Independent Study Project (ISP) Collection

The Great Barrier Reef Marine Park (GBRMP) provides outstanding ecological, cultural, social, and economic services to the number of communities that use it. Most of the park is regulated via a zoning system designed to protect its biodiversity and ensure the sustainable use of its resources (GBRMPA, 2004). Like any social institution, zoning regulations rely heavily on compliance in order to be effective. Recreational fishing on the GBRMP accounts for most of the noncompliance behavior associated with zoning (Arias and Sutton, 2013). Thus, understanding fishers compliance behavior is central to understanding how to best manage these areas. Using results from …