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Articles 421 - 450 of 86258
Full-Text Articles in Entire DC Network
Older Recent Widows’ Physical Activity Before And After Spouses’ Deaths A Qualitative Investigation Of The Impact Of Duration And Intensity Of Care Work And Social Support, Mary Theresa Pagan
Older Recent Widows’ Physical Activity Before And After Spouses’ Deaths A Qualitative Investigation Of The Impact Of Duration And Intensity Of Care Work And Social Support, Mary Theresa Pagan
Dissertations - ALL
Abstract This study investigates and expands understanding of how care work, widowhood, social support, and physical activity intersect in the lives of older recent widows. The study addresses three primary research questions examining the duration and intensity of care work, pre- and post-death social support, and factors that influenced widows’ physical activity before and after the death of their spouses. Thirty semi-structured, face-to-face interviews conducted with heterosexual widows aged 60 and older residing in Upstate New York who were widowed within 6–24 months prior to interview. Interviews explored care work experiences, social support, widowhood transitions, and both structured and non-structured …
Degrees And Certificates Awarded To Native American Students In Nevada, 2010-2022, Devin Streuter, Kevin Yang, Caitlin J. Saladino, William E. Brown Jr.
Degrees And Certificates Awarded To Native American Students In Nevada, 2010-2022, Devin Streuter, Kevin Yang, Caitlin J. Saladino, William E. Brown Jr.
Higher Education
This fact sheet presents data on certificates and degrees awarded to Native Americans from the Nevada System of Higher Education’s (NSHE) teaching institutions —College of Southern Nevada (CSN), Great Basin College (GBC), Nevada State University (NSU), Truckee Meadows Community College (TMCC), University of Nevada, Las Vegas (UNLV), University of Nevada, Reno (UNR), and Western Nevada College (WNC)— from 2010 to 2022. Additionally, the fact sheet reports data on degree type, gender, and the most common majors pursued by Native American certificate and degree earners in Nevada. The data are derived from the Nevada P-20 Workforce Research (NPWR) Data System.
Career Decidedness Among Multicultural Adolescents In South Korea: Relational Support And Internalized Psychological Resources, Kahyen Shin
Dissertations - ALL
Despite the growing number of multicultural adolescents in South Korea, little is known about how to support their career development. Specifically, Korean multicultural adolescents who have foreign-born mothers and Korean fathers have experienced educational and career gaps compared to non-multicultural adolescents in Korea. Given that relational supports are documented to have significant associations with adolescents' career decidedness, this study aims to examine the relationship between relational supports and career decidedness through internalized psychological resources such as self-esteem and achievement motivation. Grounded in the Relational Theory of Working (RTW; Blustein, 2011), the researcher focused on the mediating role of internalized psychological …
Inundated With Uncertainty: A Cartographic Assessment Of Fema’S Flood Insurance Rate Maps (Firms) And Flood Risk Discourse, Michael Cabal
Inundated With Uncertainty: A Cartographic Assessment Of Fema’S Flood Insurance Rate Maps (Firms) And Flood Risk Discourse, Michael Cabal
Theses - ALL
Flooding accounts for almost 90% of all natural disasters in the United States. FEMA (Federal Emergency Management Agency) is the authoritative agency tasked with mapping Special Flood Hazard Areas (SFHAs) that determine high-risk flood zones. These maps, known as Flood Insurance Rate Maps (FIRMs), are used to establish mandatory flood insurance requirements, regulate local floodplain building requirements, inform future development, and mitigate potential flood damage. However, the process for updating and implementing flood maps has come under significant scrutiny for being oversimplified, inaccurate, and incomplete. Despite existing scholarship on the shortfalls of FEMA’s recent responses to disasters, there is limited …
A Study On Gender Equality And Geographic Homogeneity In Education And Their Association With Midlife Suicide, Julene Kemp Cooney
A Study On Gender Equality And Geographic Homogeneity In Education And Their Association With Midlife Suicide, Julene Kemp Cooney
Dissertations - ALL
ABSTRACT Suicide consistently ranks among the top five causes of death for the U.S. population aged 25-64, and suicide rates have been rising in the United States since 2000. Although targeted efforts have been made to reduce suicide deaths among high-risk individuals, the upstream, or “contextual,” causes of poor mental health that drive suicidal ideation and completion are fueling a national mental health crisis that is overwhelming available mental health resources, resulting in a significant and needless loss of life. This three-chapter dissertation examines how suicide rates among midlife adults in the United States are associated with several upstream contexts …
Instructions To Authors, Academy Editors
Instructions To Authors, Academy Editors
Journal of the Arkansas Academy of Science
No abstract provided.
Journal Acknowledgements And Editorial Board, Academy Editors
Journal Acknowledgements And Editorial Board, Academy Editors
Journal of the Arkansas Academy of Science
No abstract provided.
Keynote Address And Meeting Program, Academy Editors
Keynote Address And Meeting Program, Academy Editors
Journal of the Arkansas Academy of Science
No abstract provided.
Sperm Morphology In The Eastern Narrow-Mouthed Frog, Gastrophryne Carolinensis (Anura: Microhylidae), S. E. Trauth
Sperm Morphology In The Eastern Narrow-Mouthed Frog, Gastrophryne Carolinensis (Anura: Microhylidae), S. E. Trauth
Journal of the Arkansas Academy of Science
Studies by Scheltinga et al. (2002) and Scheltinga and Jamieson (2003) provide the most comprehensive analysis and only review of sperm morphology in Narrow-Mouthed Frogs (family Microhylidae). Of the 490+ species known to occur in this anuran family (Vitt and Caldwell 2014), only 3 are distributed in the United States (Powell et al. 2016), and 2 of these occur in Arkansas (Trauth et al. 2004). Surprisingly, sperm studies on only 12 microhylid species have been conducted (Scheltinga and Jamieson 2003), and no sperm studies are available on any North American species.
Multiple Nuclear Configurations And Microtubular Arrangements In Spermatozoa Of The Western Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth
Journal of the Arkansas Academy of Science
I examined the ultrastructure of spermatozoa of the Western Siren, Siren nettingi, using transmission electron microscopy. My primary objective in this study was to elucidate, for the first time, the unique morphological complexity of biflagellated sperm in this species. This study also represents my fifth addition in a series of investigations that highlight the novel nature of all aspects of spermatogenesis in this salamander I show the basic sperm transverse and sagittal design which includes a nucleus, 2 axial fibers supporting 2 undulating membranes which have 2 axonemes residing at their terminal ends, several circular mitochondria, and several electron-dense masses. …
Binucleation And Seasonal Cycle Of Sertoli Cells In The Western Lesser Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth
Binucleation And Seasonal Cycle Of Sertoli Cells In The Western Lesser Siren, Siren Nettingi (Caudata: Sirenidae), S. E. Trauth
Journal of the Arkansas Academy of Science
I examined binucleation and the seasonal cycle of Sertoli cells in the Western Siren (Siren nettingi) using light microscopy and transmission electron microscopy. My primary objective in this study was to report, for the first time, the presence of double nuclei in Sertoli cells in a salamander. This study also represents the sixth contribution in a series of investigations that highlight the novel nature of all aspects of spermatogenesis in this unique salamander. My findings add to a growing list of extraordinary morphological and reproductive features that distinguish this salamander from all other vertebrates.
Journal Of The Arkansas Academy Of Science Volume 79, Academy Editors
Journal Of The Arkansas Academy Of Science Volume 79, Academy Editors
Journal of the Arkansas Academy of Science
No abstract provided.
A Scoping Review Of Sycophancy In Large Language Models: Operational And Theoretical Recognition, Kallen Zhou, Manning Littlejohn, Isabella Garrard
A Scoping Review Of Sycophancy In Large Language Models: Operational And Theoretical Recognition, Kallen Zhou, Manning Littlejohn, Isabella Garrard
Endeavors: Mississippi State Undergraduate Research Journal
As large language models (LLMs) usage grows across different domains, sycophancy, the tendency for output to align with users, is increasingly being recognized as a primary issue arising from applying LLMs into critical areas. Current research has provided a variety of theoretical definitions, mitigation techniques, and quantification for sycophancy. However, there is little to no consistency across different papers. This scoping review seeks to connect different works on LLM sycophancy by identifying themes in theoretical definitions, measurement methods, and inducement techniques of sycophancy. By analyzing 26 papers (preprints, conference proceedings, and journal articles) from arXiv, ACL Anthology, and Scopus, this …
Performance Of A Fertilizer Sludge Contaminated With Heavy Metals Collected From Two Wastewater Treatment Plants On (Lactuca Sativa), Leila Lila Belkhedim, Yamina Tahri
Performance Of A Fertilizer Sludge Contaminated With Heavy Metals Collected From Two Wastewater Treatment Plants On (Lactuca Sativa), Leila Lila Belkhedim, Yamina Tahri
Makara Journal of Science
The improper management of sewage sludge poses a significant global risk to environmental and public health. In this study, the valorization of sludge as an organic fertilizer for lettuce cultivation was evaluated, offering a sustainable waste-to-resource solution. Sludge from two wastewater treatment plants (Mazouna and El Kerma) were collected between 2019 and 2021. Comprehensive physicochemical analysis was conducted to determine its nutrient value and contaminant levels. In addition, the efficacy and safety of the fertilizer were assessed by measuring lettuce growth and the bioaccumulation of heavy metals in plant tissues. The analyzed sludge, with an organic matter content of 9.91%–83% …
Factors Influencing Attitudes Toward Transgender Army National Guard Personnel And Policy, Michelle Lyn Branch
Factors Influencing Attitudes Toward Transgender Army National Guard Personnel And Policy, Michelle Lyn Branch
Walden Dissertations and Doctoral Studies
No abstract provided.
Intersectional Pathways To Prison And Sentence Disparities: Exploring The Role Of Race, Gender Identity, And Sexuality In Women’S Sentencing Outcomes, Jae Collett
Dissertations and Theses
This study explores the relationship between race, gender identity, sexuality, and prison sentence length using data from the Survey of Prison Inmates, 2016. While state and federal guidelines are ostensibly in place to prevent disparate sentencing outcomes, research still finds disparities in prison sentence lengths across identities of defendants. Women generally receive more lenient sentences than men, and may be shown chivalry when processed through the criminal legal system. However, qualifications for chivalrous treatment have historically only been accessible to certain women (i.e. cisgender, heterosexual, white women). The social and institutional exclusion queer women and/or women of color experience may …
Patterns In Emotional Labor Outcomes: Assessing Seasonal Cycles Of Burnout In Minor League Sport Employees, Mandy Barefoot, Mike Martinez
Patterns In Emotional Labor Outcomes: Assessing Seasonal Cycles Of Burnout In Minor League Sport Employees, Mandy Barefoot, Mike Martinez
Global Sport Business Journal
Burnout, characterized by emotional exhaustion, depersonalization, and reduced personal accomplishment (Kristensen et al., 2005), is a growing concern among sport employees, with research documenting high levels of emotional strain, role conflict, and turnover intentions in collegiate and professional sport settings (Taylor et al., 2019; Weight et al., 2021). Although burnout is often examined as a stable condition, little attention has been given to how the cyclical nature of the sport calendar may shape its development over time.
This study examines burnout among middle managers in minor league baseball and hockey through the lens of Affective Events Theory, exploring how seasonal …
Objectively And Subjectively Measured Physical Activity Levels Among Children And Adolescents In Poland (2012–2022): A Systematic Review, Jarosław Herbert, Vasylyna Petrovets
Objectively And Subjectively Measured Physical Activity Levels Among Children And Adolescents In Poland (2012–2022): A Systematic Review, Jarosław Herbert, Vasylyna Petrovets
Baltic Journal of Health and Physical Activity
This article aims to provide a comprehensive review of research on physical activity levels among children and adolescents in Poland from 2012 to 2022, considering both objective and subjective assessment methods. A systematic review of the literature was conducted in accordance with the PRISMA reporting recommendations. PubMed, Scopus, Web of Science, Google Scholar databases, as well as Polish scientific databases were searched. The review included studies published from 2012 to 2022, on children and adolescents aged 3–18 living in Poland, assessing physical activity levels using objective and/or subjective methods. This analysis of the selected studies showed that physical activity levels …
Influence Of Peak Height Velocity On The Level Of Motor Skills And Anthropometric Features In Young Male Footballers, Dariusz Tadeusz Skalski, Magdalena Prończuk, Artur Terbalyan, Kinga Łosińska, Adam Maszczyk, Robert Krzysztof Roczniok
Influence Of Peak Height Velocity On The Level Of Motor Skills And Anthropometric Features In Young Male Footballers, Dariusz Tadeusz Skalski, Magdalena Prończuk, Artur Terbalyan, Kinga Łosińska, Adam Maszczyk, Robert Krzysztof Roczniok
Baltic Journal of Health and Physical Activity
Background: This study examines the influence of Peak Height Velocity (PHV) on motor abilities and anthropometric characteristics of young male football players aged 12–16. The research aimed to determine whether PHV significantly affects motor performance beyond the chronological age, providing insights for talent identification and training optimization. Materials and methods: A total of 248 male football players from four professional academies were assessed and categorized into three maturation groups: Pre-PHV (n = 95, 38.3%), Mid-PHV (n = 98, 39.5%), and Post-PHV (n = 55, 22.2%) Anthropometric measurements included height, body mass, BMI, and leg length, while motor tests …
Advocating For A Care-Based Ethic: Stories Of Pregnancy And Birth From Caregivers Of Children With Down Syndrome, Lydia Ocasio-Stoutenburg, Nayma Sultana Mim
Advocating For A Care-Based Ethic: Stories Of Pregnancy And Birth From Caregivers Of Children With Down Syndrome, Lydia Ocasio-Stoutenburg, Nayma Sultana Mim
Developmental Disabilities Network Journal
Down syndrome (DS) impacts about 1 in every 640 childbirths in the United States. While quality of life has improved for people with DS, systemic inequities and deficit-based perceptions have persisted throughout history, with material impacts on people with DS and their caregivers. Researchers have documented how caregivers of children with DS have had negative experiences with healthcare providers and genetic counselors, whose biased views about DS translate into subtle and overt pressures. Few studies explicitly focus on the experiences of Caregivers of Color, multilingual families, as well as families with varying economic experiences who have children with DS. This …
Toward A Metric For Disciplinary Learning In The Age Of Ai: The Unblooms™ Metacognitive Awareness Scale And Discernment Rate In Ai-Mediated Learning, Tina R. Austin
International Journal of Emerging and Disruptive Innovation in Education : VISIONARIUM
Telling students to “reflect on their own thinking” has become insufficient in AI-mediated learning environments. When students are rewarded for polished outputs, cognitive offloading to AI tools becomes rational, and traditional snapshot assessments (single-moment evaluations of task completion) produce false signals about whether durable learning has occurred. This problem is sharpened by the broader shift in AI learning tools toward Socratic tutors, study modes, Khan Academy's Khanmigo, and agentic systems that can shape the learner’s process over time. Lodge and Loble (2026) distinguish beneficial cognitive offloading, which frees working memory for intrinsic learning, from detrimental outsourcing, which bypasses the cognitive …
A Guide To Change Management Using The Sarah Model, Sara Kern, Sarah Barbrow, Sarah Jane Dooley, Sarah E. Lester, Sarah Over
A Guide To Change Management Using The Sarah Model, Sara Kern, Sarah Barbrow, Sarah Jane Dooley, Sarah E. Lester, Sarah Over
Library Scholarship
Academic libraries are the heart of colleges and universities and, as such, are often centrally involved in and impacted by changes in the greater higher education landscape. For those working in these spaces, familiarity with strategies for managing change is essential to support yourself and others during especially turbulent times. The SARAH model, described below in bullet points with our modifications in brackets, offers a memorable way to understand responses to change, be they our own or others.
S - Shock or Surprise
A – Anger [Anxiety, Alert, or Anticipation]
R – Resistance or Rejection [Re-engagement, or Rationalization]
A - …
I Will Defend My Self, Emily Ward Hawkins
I Will Defend My Self, Emily Ward Hawkins
Theses and Dissertations
This thesis examines caregiving and motherhood as forms of load-bearing infrastructure. Cultural narratives often portray motherhood through sentimental images of joy, tenderness, and devotion, obscuring the structural labor that sustains family life. This project examines maternal labor as a largely unseen system of support that organizes family life while often remaining backgrounded. Caregiving reorganizes time, space, ambition, embodiment, and future orientation within maternal life. Through sculptural works using architectural materials and construction systems, such as oriented strand board, blueprint racks, metal armatures, and graph paper, the project visualizes caregiving as a structural condition. These materials reference the language of architecture …
Institutional Influences And The Governance And Administration Of The Programa Produtor De Água Payment For Ecosystem Services Program In Brazil, Thomas G. Safford
Institutional Influences And The Governance And Administration Of The Programa Produtor De Água Payment For Ecosystem Services Program In Brazil, Thomas G. Safford
Faculty Publications
Payment-for-Ecosystem-Services (PES) has been promoted as an innovative approach to environmental governance capable of simultaneously advancing conservation and sustainable development objectives. While studies commonly assess the ecological and economic performance of PES schemes, less attention has been given to their organizational and administrative effectiveness. This study examines these governance dimensions of one of Latin America’s most prominent PES initiatives—the Water Producer Program (WPP) in Brazil. Drawing on a meta-synthesis of 125 publications, the analysis investigates how regulative, normative, and cultural-cognitive institutional forces shaped WPP implementation. Guided by neo-institutional theory and institutional bricolage, findings show that WPP governance operated through hybrid …
Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue
Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue
Bulletin of Chinese Academy of Sciences (Chinese Version)
The biopharmaceutical industry is a critical domain underpinning national scientific and technological innovation development and public health. With the rapid advancement of artificial intelligence (AI) and its deep integration with the life sciences, biomedicine research is undergoing a paradigm shift from traditional experience-driven trial-and-error approaches to data-driven and predictive validation-based models. This study systematically examines the pathways for reshaping research in biomedicine paradigms under the convergence of data-driven, mechanism-driven, and intelligence-driven approaches. It focuses on recent advances in the application of AI across key stages, including drug discovery and design, druggability evaluation, delivery system design and optimization, nonclinical and clinical …
Urban Indian Parents' Occupational Perceptions Of Play And Governance Of Children's Excessive Screen Time Preferences And Behaviours In This Digital Era, Joanna Priyadarshini Udaykumar, Tony Sam George
Urban Indian Parents' Occupational Perceptions Of Play And Governance Of Children's Excessive Screen Time Preferences And Behaviours In This Digital Era, Joanna Priyadarshini Udaykumar, Tony Sam George
International Journal of Playwork Practice
Abstract
Children’s innate urge to engage in joyous, self-directed, meaningful, iterative activities embodies their unique play experiences and facilitates their holistic development. However, the exponential growth of digital technology in an urbanized world has transformed their social landscape by offering them a plethora of novel play opportunities that ‘pushes children away from the outdoors and pulls them indoors’. Moreover, the radical transition from nature-based recreation to media-centric activity insinuates the surge of a global pandemic characterized by low physical activity, sleep deprivation and sedentary, lifestyle diseases. This emerging trend reflects children’s predilection for videophilia over biophilia due to the dominance …
Disaster Preparedness, Prevention And Management In Lagos State University Library, Mausi A. Bokoh, Sophia V. Adeyeye Dr, Oluwaseun Adeola Abiodun-Asanre, Mrs
Disaster Preparedness, Prevention And Management In Lagos State University Library, Mausi A. Bokoh, Sophia V. Adeyeye Dr, Oluwaseun Adeola Abiodun-Asanre, Mrs
Library Philosophy and Practice (e-journal)
Disasters pose significant threats to human lives, infrastructure, and national socioeconomic development. Effective disaster preparedness, prevention, and management are therefore vital for mitigating their impact and ensuring continuity of operations. This study examined disaster preparedness, prevention, and management practices at Lagos State University Library. A survey research design was adopted, and data were collected through a structured questionnaire covering key aspects of disaster management. Frequency counts, percentages, mean, and standard deviations were used to analyze data. The findings revealed that the library employs basic preventive strategies such as turning off electricity after work hours and ensuring timely evacuation during emergencies. …
Disciplinary System Of Artificial Intelligence: Connotation, Architecture, And Development Suggestions, Academic Divisions Of The Chinese Academy Of Sciences Discipline Group Of Advisory Project On Ai-Empowered Scientific Research
Disciplinary System Of Artificial Intelligence: Connotation, Architecture, And Development Suggestions, Academic Divisions Of The Chinese Academy Of Sciences Discipline Group Of Advisory Project On Ai-Empowered Scientific Research
Bulletin of Chinese Academy of Sciences (Chinese Version)
The discipline of artificial intelligence studies the theories, methods, systems, applications, enabling functions, ethics, and governance of artificial intelligence, and is a typical interdisciplinary field. With the rapid development of artificial intelligence in recent years, its disciplinary connotations and system architecture urgently require renewed examination. Based on the analysis of development trends of artificial intelligence, this paper elucidates the connotations of the AI discipline from four perspectives: theoretical methods, forms of intelligence, disciplinary integration, and application empowerment. It further proposes a disciplinary system framework for artificial intelligence comprising foundational supporting disciplines, core body of knowledge, major forms of intelligence, and …
Artificial Intelligence Empowers Particle Physics And Nuclear Physics: From Fundamental Research To Major Applications, Yifang Wang, Yuan He, Yao Huang, Wanbing He, Yi Jiao, Congqiao Li, Ke Li, Beijiang Liu, Yingqi Ma, Yugang Ma, Longgang Pang, Fazhi Qi, Sichao Tan, Chunpeng Wang, Meng Wang, Xiaoheng Xu, Xing Xu, Zhentang Zhao, Yingxun Zhang, Zhengde Zhang, Hongwei Zhao, Lina Zhao
Artificial Intelligence Empowers Particle Physics And Nuclear Physics: From Fundamental Research To Major Applications, Yifang Wang, Yuan He, Yao Huang, Wanbing He, Yi Jiao, Congqiao Li, Ke Li, Beijiang Liu, Yingqi Ma, Yugang Ma, Longgang Pang, Fazhi Qi, Sichao Tan, Chunpeng Wang, Meng Wang, Xiaoheng Xu, Xing Xu, Zhentang Zhao, Yingxun Zhang, Zhengde Zhang, Hongwei Zhao, Lina Zhao
Bulletin of Chinese Academy of Sciences (Chinese Version)
Particle physics and nuclear physics are core foundational disciplines for exploring the fundamental structure of matter and the origin of the universe. The deep integration of artificial intelligence (AI) technology is providing entirely new pathways to address systemic challenges such as the processing of massive amounts of multimodal data, the realization of extreme experimental conditions, bottlenecks in theoretical calculations, and the intelligent control of large-scale scientific facilities. The article systematically elaborates on how AI deeply empowers particle physics and nuclear physics, particularly in major application scenarios such as research on the fundamental structure and origin of mass of matter, the …
Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han
Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han
Bulletin of Chinese Academy of Sciences (Chinese Version)
Life related processes are characterized by high dimensionality and multi-scale properties. Understanding mechanisms underpinning life processes helps promote national healthcare, agricultural development, sustainable ecological civilization, and national security. Current life science research is confronted with an enormous challenge of dimensionality stemming from data explosion and data fragmentation, for which the recent rapid advancement of artificial intelligence (AI) provides novel solutions. AI will catalyze a paradigm shift in life science research from the current experiment based empirical induction to a new closed-loop knowledge acquisition including large scale data collection, model building, model prediction, experimental validation, and iterative of these procedures. Life …