Digital Commons Network^™

Evidence Review And Considerations For Use Of First Line Genome Sequencing To Diagnose Rare Genetic Disorders, Kristen M Wigby, Deanna Brockman, Gregory Costain, Caitlin Hale, Stacie L Taylor, John Belmont, David Bick, David Dimmock, Susan Fernbach, John Greally, Vaidehi Jobanputra, Shashikant Kulkarni, Elizabeth Spiteri, Ryan J Taft

Center for Medical Ethics and Health Policy Staff Publications

Early use of genome sequencing (GS) in the diagnostic odyssey can reduce suffering and improve care, but questions remain about which patient populations are most amenable to GS as a first-line diagnostic test. To address this, the Medical Genome Initiative conducted a literature review to identify appropriate clinical indications for GS. Studies published from January 2011 to August 2022 that reported on the diagnostic yield (DY) or clinical utility of GS were included. An exploratory meta-analysis using a random effects model evaluated DY based on cohort size and diagnosed cases per cohort. Seventy-one studies met inclusion criteria, comprising over 13,000 …

Examining Crises Resilience In Tourism : A Systematic Review Of Literature, Kanyamwa Lunanga Félix, George Ariya, Priscillah Omagwa

Journal of Sustainability and Resilience

This study is the systematic review of literature on the resilience of tourism businesses. Following the various crises and disasters that shook the World between 2000 and 2020, the interest of researchers in tourism resilience has increased significantly. Despite the interest felt by these scientists, the notion of resilience has remained fragmented in terms of its definition and dimensions. This review presents an overview of the literature on the resilience of tourism businesses from 2013 to June 2023. The study revealed that there is a lack of cohesion in the literature on resilience from the definition to its influencing factors. …

Economic Effects Of Pandemic On Us And Indian Economies With Policy Actions In 2019-2023: A Comparative Analysis, Kishore Kukarni Dr., Amitabh S. Dutta

International Review of Business and Economics

COVID 19 pandemic that started in February/March 2019, with happenings in Yuwan, China spread like a wildfire all over the world. All countries faced one of the worst economic challenges in recent centuries if not ever in the history of the mankind. Early predications were so severe and devastating that some forecasters predicted a death-toll of 100 million all over the world, as the virus was not only spreading fast but also had no solution for its serious fatal effects. It was evident that the patients were dying before getting any effective treatments and many of them were elderly individuals. …

“To Be Straight Or Closeted:” Lesbian, Gay, And Bisexual College Women In Greek Life In The Context Of The Lgb Experience In The United States, Olivia Morreale

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

How The Physical, Social, And Psychological Environment Impacts Border Security, John J. Smietana Jr.

Doctoral Dissertations and Projects

Crime prevention through environmental design (CPTED) is a theory of crime control that posits that crime can be mitigated by shaping the physical, psychological, and social environment to prevent the meeting of perpetrators and victims. Over several decades, the United States applied the principles of CPTED to the United States-Mexico border in San Diego to secure the international border. Despite the sovereign right to secure the international border, border security became a divisive and emotionally charged topic in the United States. Studies on the effectiveness of border security were qualitative and humanitarian, describing how border security negatively impacted certain groups …

Fake News: Finding Truth In Strategic Communication, Anne Damisa

Doctoral Dissertations and Projects

Fake news is an old phenomenon that has become a new obsession and a menace to society due to technological advancement and the proliferation of social media, which has changed traditional journalism norms. As the spread of false information has increased these past few years, it has become increasingly difficult for information consumers to distinguish between facts and fakes. A comprehensive systematic literature review to extract themes revealed the major factors responsible for spreading fake news. This qualitative interpretative meta-synthesis (QIMS) aims to better understand and offer solutions to combat fake news. This Ph.D. dissertation will serve as a guide …

The Potential Of Ethiopian Medicinal Plants To Treat Emergent Viral Diseases, Mekbib Fekadu, Ermias Lulekal, Solomon Tesfaye, Morgan Ruelle, Nigist Asfaw, Tesfaye Awas, Kebu Balemie, Kaleab Asres, Sebastian Guenther, Zemede Asfaw, Sebsebe Demissew

Sustainability and Social Justice

Ethiopians have deep-rooted traditions of using plants to treat ailments affecting humans and domesticated animals. Approximately 80% of the population continues to rely on traditional medicine, including for the prevention and treatment of viral diseases. Many antiviral plants are available to and widely used by communities in areas where access to conventional healthcare systems is limited. In some cases, pharmacological studies also confirm the potent antiviral properties of Ethiopian plants. Building on traditional knowledge of medicinal plants and testing their antiviral properties may help to expand options to address the global pandemic of COVID-19 including its recently isolated virulent variants …

Impact Of Covid-19 On Unaccompanied Immigrant Minors And Families: Perspectives From Clinical Experts And Providers, Amanda Venta, Ashley Bautista, Luz M. Garcini, Michelle Silva, Alfonso Mercado, Oscar F. Rojas Perez, Norma Pimentel, Kathryn Hampton

Psychological Science Faculty Publications

The number of unaccompanied immigrant minors (UIMs) and families from Central America seeking asylum in the U.S. continues to rise. This growth, combined with restrictive government policies, led to crowded and suboptimal conditions in Customs and Border Patrol and non-governmental organization facilities. COVID-19 further taxed facilities and exacerbated uncertainty surrounding length of detention, basic human rights, and family reunification. The current project features testimonies from the authors who work as clinical experts and providers in Texas – a top destination for Central American immigrants. In collaboration with a deputy director of a not-for-profit human rights organization, volunteer psychologists, and the …

Effectiveness Of Antibiotic Stewardship For Healthcare Providers At Urgent Care Clinics, Helen T. Adewole

Electronic Theses and Dissertations

Antibiotics have revolutionized modern medicine; however, the overuse in urgent care and primary care significantly contributes to the global burden of infections resistant to available antimicrobial medicines. Approximately 30% of the antimicrobials prescribed in acute care settings are unnecessary. Patient demand for antibiotics has seemingly skyrocketed following the recent COVID-19 pandemic. Practitioners must be knowledgeable about antibiotic stewardship initiatives, such as the wait-and-see approach, to reduce antibiotic overuse and improve the trajectory of antibiotic resistance and patient health outcomes. The gap in practice was the limited awareness of scientific evidence-based tools to partner with patients and improve antibiotic prescription patterns. …

Risk Factors For Childhood Brain Tumours: A Systematic Review And Meta-Analysis Of Observational Studies From 1976 To 2022, Felix M Onyije, Roya Dolatkhah, Ann Olsson, Liacine Bouaoun, Isabelle Deltour, Friederike Erdmann, Audrey Bonaventure, Michael E Scheurer, Jacqueline Clavel, Joachim Schüz

Center for Medical Ethics and Health Policy Staff Publications

BACKGROUND: Childhood brain tumours (CBTs) are the leading cause of cancer death in children under the age of 20 years globally. Though the aetiology of CBT remains poorly understood, it is thought to be multifactorial. We aimed to synthesize potential risk factors for CBT to inform primary prevention.

METHODS: We conducted a systematic review and meta-analysis of epidemiological studies indexed in the PubMed, Web of Science, and Embase databases from the start of those resources through 27 July 2023. We included data from case-control or cohort studies that reported effect estimates for each risk factor around the time of conception, …

Ideology Of Disaster Education Trauma Handling Post-Earthquake In Picture Stories Book: Critical Discourse Analysis, Silvia Damayanti, I Nyoman Suarka, Maria Matildis Banda, Ketut Widya Purnawati

International Review of Humanities Studies

This research analyzes the ideology that the author intends to instill in picture storybooks for children in Japan. The study aims to explore how the author conveys the ideology of handling trauma in children after earthquake disasters. The objects of the study are two picture storybooks titled "Yuzuchan" and "Yappari Ouchi Ga Ii Na." The research was conducted qualitatively using the documentary data search method. The analysis was carried out with van Dijk's CDA theory and Peirce's Semiotics Theory. The results of the analysis reveal that "Yuzuchan" and "Yappari Ouchi Ga Ii Na" are picture storybooks produced to help children …

Nigerian Politicians And Language Use During Political Compaigns: A Studi Of Select Speeches, Miriam Stephen Inegbe

International Review of Humanities Studies

This essay appraised linguistic features in selected utterances of some prominent and leading Nigerian politicians during political rallies held between October and December, 2022. These utterances, which serve as data for this paper were extracted from some Nigerian tabloids like NaijaNews.com, Opera News, Politic.nigeria.com, RealMedia, Vanguard News, Voice of the People (VoP) and www.thisdaylive.com. In linguistics, utterances are viewed as unit of speech. The significant meaning of speech, therefore, embeds in the utterance which may provide a basis for social positions and further interpretative actions or decisions by the listener. The data for this study were eleven (11) purposively selected …

The Narratives Of Participation In Restorative Justice Programs In Formerly Incarcerated African American Men, Jerry D. Elster

Walden Dissertations and Doctoral Studies

No abstract provided.

Research Progress In High-Throughput Phenotype Testing Technology And Equipment For Engineering Cells Based On Microfluidics, Shuang Li, Xiaojie Guo, Haibo Chen, Sisi Chen, Xin Da, Zhenghui Li, Qinxiu Liu, Yi Wang, Xinhui Xing, Chong Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Engineering cells are a core component of green bio-manufacturing. The efficient testing and acquisition of engineering cells with the desired phenotype is a critical factor in the successful implementation of bio-manufacturing. In recent years, based on microfluidics technologies, non-culture type single-cell phenotype high-throughput test equipment and culture type phenotype high-throughput test equipment for the growth and metabolism of single cell in a bioreactor have been developed such as microdroplet and microchamber, realizing high-throughput, automated, miniaturized, and integrated testing of the phenotypes of engineering cells and providing a powerful tool for the breeding of engineering cells. This review systematically compiles the …

Analysis On Development Status And Characteristics Of Non-Governmental Bio-Safety And Bio-Security Think Tanks In The United States, Wenbing Ma, Qiang Song, Lei Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

At present, the complexity of bio-safety governance is becoming increasingly prominent, and complex issues such as security and development in the bio-economy, preparedness and response to infectious disease pandemics, the interweaving and integration of bio-security and other security factors, and the integration of scientific and technological factors and security factors urgently require think tanks to conduct systematic, comprehensive and forward-looking assessments and provide professional solutions. Rooted in the relatively mature experience in the construction of think tanks in the United States, a number of bio-safety and bio-security think tanks with greater influence have been developed, which have acted as an …

Exploring The Role Of Information And Communication Technologies In Allergic Rhinitis In Specialist Centers: Patient Perspectives On Usefulness, Value, And Impact On Healthcare, Ivan Cherrez-Ojeda, Jean Bousquet, Zouina Sarfraz, Azza Sarfraz, Monica Rodriguez Gonzales, Anna Bedbrook, Nelson Rosario, Benjamin Zepeda-Ortega, Guillermo Guidos, Ulbio Alcivar Molina

Department of Paediatrics and Child Health

Introduction: Information and communication technologies (ICTs) improve patient-centered care and are routinely used in Allergic Rhinitis (AR), but patients' preferences and attitudes are unexplored. This study examines AR-related information preferences and ICT use by AR patients.
Methods: A survey-based cross-sectional study was carried out in Ecuador from July to September 2019 in seven centers of reference for allergic disease. Participants were 18 years or older, diagnosed with AR and had access to ICT and the Internet. Descriptive and binomial logistic regressions were performed. A value of less than 0.05 was considered statistically significant.
Results: 217 patients were included. 47% (n …

The Hiv/Aids Epidemic In Miami: Perspectives Of Stakeholders And Frontline Providers, Tracy Pugh, Carrigan L. Parish, Pedro C. Castellon, Allan Rodriguez, Michael A. Kolber, Lisa R. Metsch

Florida Public Health Review

Background: Miami, Florida persists as an epicenter of HIV/AIDS nationally and has been more delayed than other areas with high HIV burden in implementing public health measures that mitigate transmission risk. These issues among other social and structural-level determinants have complicated progress in addressing HIV/AIDS in Miami.

Purpose: The stagnated progress in improving HIV outcomes in Miami necessitated a more comprehensive understanding of the experiences and insights of stakeholders within the system. We used a stakeholder analysis approach to understand the complexity of driving factors and key challenges facing this HIV epidemic.

Methods: A stakeholder analysis was conducted …

Conceptualizing Maritime-Based Decentralization Toward Better Public Service In The Archipelagic Region, Restu Karlina Rahayu, Ratnaningsih Damayanti, Mayuko Galuh Mahardika

Jurnal Wacana Politik

The purpose of this study is to demonstrate how decentralization affects public services differently in Sumenep Regency’s mainland and island regions. Twenty-seven subdistricts make up the Sumenep Regency; nine of these are dispersed as islands, while eighteen are situated on Madura Island. The discrepancies in growth between mainland and island are caused by this geographic structure. The infrastructure, health, and education sectors are the main subjects of this study. According to this study, obstacles that impede the optimization of education in island locations include school references and far from the Education Office and the Ministry of Religion’s oversight. In the …

Aligning Tobacco Free Living Agendas In A Community Health Improvement Plan: A Case Study On Democratic Participation And Economic Interests In U.S. Health Policy Development, David B. Tataw

Journal of Public Management & Social Policy

This paper addresses the gap in studies which use democratic policy making frameworks to analyze health policy development in Community Health Improvement Plans (CHIPs). The study describes and analyzes three streams of the tobacco free living policy cycle in a Community Health Improvement Plan implemented in a Mid-Western Region of the United States from 2016 to 2020. The roles of public health interest, economic interests, and democratic participatory rights in Tobacco free health policy making are assessed. The policy making process is assessed within an integrated framework of analysis that weaves pluralist, power elite, critical democratic theories, and participatory governance …

Fitting A Covid-19 Model Incorporating Senses Of Safety And Caution To Local Data From Spartanburg County, South Carolina, D. Chloe Griffin, Amanda Mangum

CODEE Journal

Common mechanistic models include Susceptible-Infected-Removed (SIR) and Susceptible-Exposed-Infected-Removed (SEIR) models. These models in their basic forms have generally failed to capture the nature of the COVID-19 pandemic's multiple waves and do not take into account public policies such as social distancing, mask mandates, and the ``Stay-at-Home'' orders implemented in early 2020. While the Susceptible-Vaccinated-Infected-Recovered-Deceased (SVIRD) model only adds two more compartments to the SIR model, the inclusion of time-dependent parameters allows for the model to better capture the first two waves of the COVID-19 pandemic when surveillance testing was common practice for a large portion of the population. We find …

2024, Camp Research Forum Book Of Abstracts, American Camp Association

ACA National Camp Research Forum Abstracts

This book includes 29 abstracts that will be presented at the 2024 American Camp Association (ACA) Research Forum to be held during the ACA annual conference from February 5-9 in New Orleans, LA. Abstracts have been grouped into similar areas and will be presented across five verbal sessions and one poster session.

Coping With The Covid-19 Pandemic: Examining Meaning-Making In A Socioecological Framework, Emilia Eva Mikrut

Theses and Dissertations

During 2020, the COVID-19 pandemic emerged as a threatening, unpredictable, and uncontrollable stressor. Meaning-making, or one’s ability to make sense of a stressful life event, integrate the event into one’s narrative of the world and meaning in life, and accordingly revise life goals, is a salient intrapsychic process contributing to psychological adjustment in the face of very stressful or traumatic experiences such as chronic health issues, interpersonal grief, and natural and man-made disasters. Early findings provide evidence for the critical role of meaning-making in coping with stressors associated with the COVID-19 pandemic. Though meaning-making is a universal process, one’s capacity …

Healthy Acadia Downeast Community Opioid Response Program: Year 3 Summary, Tyler Egeland Ba, Gordon Mcintire Ba, Evelyn Ali, Mary Lindsey Smith Phd, Katie Rosingana Ba

Substance Use Research & Evaluation

The Downeast Substance Treatment Network is a group of diverse organizations working to improve integration and access to treatments and services for people with substance use disorder. The consortium’s Rural Communities Opioid Response Program grant project aims to: (1) expand the reach of their treatment network, (2) increase awareness and practice of harm reduction, and (3) facilitate transitions of care to improve partner efficacy. This project included a mixed-methods evaluation led by Catherine E. Cutler Institute’s Substance Use Research and Evaluation Team (SURE). This final year 3 summary presentation includes feedback from program partners, key informants, and program clients, in …

Healthy Acadia Downeast Community Opioid Response Program: Year 2 Summary, Mary Lindsey Smith Phd, Evelyn Ali Bs, Katie Rosingana Ba

Substance Use Research & Evaluation

The Downeast Substance Treatment Network is a group of diverse organizations working to improve integration and access to treatments and services for people with substance use disorder. The consortium’s Rural Communities Opioid Response Program grant project aims to: (1) expand the reach of their treatment network, (2) increase awareness and practice of harm reduction, and (3) facilitate transitions of care to improve partner efficacy. This project included a mixed-methods evaluation led by Catherine E. Cutler Institute’s Substance Use Research and Evaluation Team (SURE). This year 2 summary presentation includes feedback from program partners, key informants, and program clients, in addition …

The Impact Of Censorship On Covid-19 Policy Formation In The United States, Victor Wallis

Faculty Works

No abstract provided.

Multidimensional Data Visualization And Synchronization For Revealing Hidden Pandemic Information, Qi Zhang, Nikhil Maram

Faculty Publications - Information Technology

Visualization is integral to uncovering hidden information in data and providing users with intuitive feedback for decision-making. Data visualization is crucial for transforming complex data into actionable insights across various domains. In recent years, coronavirus disease vaccines have become increasingly available to much of the population. However, the CDC (Centers for Disease Control and Prevention) often fails to consider multidimensional coronavirus pandemic data from a side-by-side perspective, limiting the ability of medical professionals and individuals to compare and interact with comprehensive data visualizations. Effectively displaying coronavirus and vaccination data collected from multiple sources is essential for interpreting pandemic transmission patterns …

Three Essays On Externalities Of Energy And Agricultural Production, Taiwo Foluso Akinyemi

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation consists of three essays exploring the externalities that arise from energy production and development in a developing country, Nigeria, and agricultural production in a developed nation, the United States (US). The research examines the benefits of energy development in terms of its impact on local wealth and the associated costs, including the health effects on communities living near energy production sites. Additionally, the dissertation analyzes the opportunity costs of policies aimed at preventing the relocation of nutrients, particularly nitrogen fertilizers, within the agricultural sector and their impact on the producer and consumer surplus.

The first essay examines the …

Between Wages And Wellbeing: Examining The Role Of Employers In Increasing Covid-19 Vaccine Uptake In The State Of West Virginia, Nathaniel Udoh Godwin

Graduate Theses, Dissertations, and Problem Reports (ETD)

The novel coronavirus disease 2019 (COVID-19) stretched public health systems globally, with millions of cases confirmed across all continents of the world. The United States health systems struggled as the country grappled with emerging variants of the virus, differing levels of vaccine acceptance, misinformation, and disparity in health outcomes. As COVID-19 vaccines emerged, the U.S. Government sought to bolster uptake through myriad measures, including announcing vaccine requirements for federal employees, which was met with mixed reactions. Accordingly, some employers and businesses adopted a “no jab, no job” policy, while others stopped short of mandates but encouraged and incentivized vaccine uptake …

Predictors Of Utilization Of Preventive Gynecologic Health Services Among Women Veterans, Jennifer Lynn Milore

PCOM Psychology Dissertations

As the number of women veterans in the United States increases, additional attention has been given to understanding their healthcare experiences within the Veterans Health Administration. However, much of the current literature exploring women veterans has been qualitative and little research has examined quantitative relationships between experiences in the VA healthcare system and gynecologic health behaviors and outcomes. The purpose of this study was to evaluate potential factors (health literacy, social problem-solving abilities, and perceived gender discrimination) that may predict gynecologic health behaviors in women veterans. This study included 145 anonymous participants. Participants completed screening questions and demographic and health …

Prevalence Of Non-Communicable Diseases Among Household Contacts Of People With Tuberculosis: A Systematic Review And Individual Participant Data Meta-Analysis, Yohhei Hamada, Matteo Quartagno, Farihah Malik, Keolebogile Ntshamane, Anna Tisler, Sanjay Gaikwad, Carlos Acuna-Villaorduna, Perumal Kannabiran Bhavani, Bachti Alisjahbana, Katharina Ronacher, Lika Apriani, Mercedes Becerra, Alexander L. Chu, Jacob Creswell, Gustavo Diaz, Beatriz E. Ferro, Jerome T. Galea, Louis Grandjean, Harleen M. Grewal, Amita Gupta, Edward C. Jones-López, Léanie Kleynhans, Leonid Lecca, Peter Macpherson, Megan Murray, Diana Marín, Blanca I. Restrepo, Shri Vijay Shivakumar, Eileen Shu, Dhanasekaran Sivakumaran, Luan Nguyen Vo, Emily L. Webb, Andrew Copas, Ibrahim Abubakar, Molebogeng X. Rangaka

Social Work Faculty Publications

Objective: To investigate the prevalence of non-communicable diseases among household contacts of people with tuberculosis.

Methods: We conducted a systematic review and individual participant data meta-analysis. We searched Medline, Embase and the Global Index Medicus from inception to 16 May 2023. We included studies that assessed for at least one non-communicable disease among household contacts of people with clinical tuberculosis. We estimated the non-communicable disease prevalence through mixed effects logistic regression for studies providing individual participant data, and compared it with estimates from aggregated data meta-analyses. Furthermore, we compared age and sex-standardised non-communicable disease prevalence with national-level estimates standardised for …