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The Current - Volume 35 Issue 1 (Including Special Section On Sports), Nova Southeastern University
The Current - Volume 35 Issue 1 (Including Special Section On Sports), Nova Southeastern University
Student Newspapers
No abstract provided.
Driving Green Investments To Address Climate Change, Baptiste Gibrat
Driving Green Investments To Address Climate Change, Baptiste Gibrat
Dartmouth College Master’s Theses
The climate crisis is no longer news, and society needs to accelerate the transition to net zero emissions. Otherwise, the consequences of climate change will become increasingly catastrophic.
This thesis develops a framework to drive green investments, which reduce society’s dependance on fossil fuels. Initially, the research provides a comprehensive examination of these investments, followed by an exploration of three strategies to enhance their adoption: leveraging financial instruments and capital markets, implementing regulatory frameworks, and harnessing the power of technologies. To integrate these elements within a comprehensive framework, the study employs market research, reviews relevant literature, and includes interviews with …
The Impact Of The Covid-19 Pandemic On Depression And Anxiety Among Idaho Adults, Melissa Marie Henbest
The Impact Of The Covid-19 Pandemic On Depression And Anxiety Among Idaho Adults, Melissa Marie Henbest
Walden Dissertations and Doctoral Studies
Research indicates that the COVID-19 pandemic had negative repercussions on the mental health of U.S. citizens. The purpose of this study was to explore the impact the COVID-19 pandemic had on depression and anxiety on a population aged 18 years and older. Using a quantitative correlational repeated design, archival data were analyzed to evaluate the change in depression (as measured using the Patient Health Questionnaire-9) and anxiety (as measured using the Generalized Anxiety Disorder-7 [GAD-7]) indices from a non-pandemic year (2019) to the 1st pandemic year (2020) among patients of an outpatient community health care center. The study took into …
Past And Present Of The Cvs: Empirical Research And Evidence-Based Policy, Kevin T. Wolff
Past And Present Of The Cvs: Empirical Research And Evidence-Based Policy, Kevin T. Wolff
Publications and Research
In this keynote address, I emphasized the critical role of accurate crime measurement in developing evidence-based policies. I discussed the "dark figure of crime," highlighting how many crimes go unreported, and stressed the importance of victimization surveys in uncovering these hidden crimes to provide a more complete picture of criminal activity.
I also explored how technological advancements, particularly AI, are transforming how we collect and analyze crime data. While AI offers significant benefits in predictive policing and resource allocation, I cautioned about the risks of bias and privacy issues that must be managed carefully.
Regional collaboration, standardization, and inclusivity are …
Exploring Leadership Characteristics And Their Effects On Sustaining Federally Qualified Health Centers, Eleace E. Sawyers
Exploring Leadership Characteristics And Their Effects On Sustaining Federally Qualified Health Centers, Eleace E. Sawyers
Walden Dissertations and Doctoral Studies
An argument can be made for the continued existence of Federally Qualified Health Centers (FQHCs) because of the level of importance of the service they provide to society. The problem addressed in this research is that despite the millions of people in need of affordable health care, the leaders of many FQHCs are fighting to keep facilities open amidst financial struggles. The purpose of this research was to identify leadership characteristics that promote FQHCs’ success by assessing effective leadership styles. This study applied a quantitative, descriptive non-experimental approach. Probability sampling was used to select the sample size and the Multifactor …
Emotional Response In Working Memory Of Individuals With Latent Toxoplasmosis, Antonella Quimbayo
Emotional Response In Working Memory Of Individuals With Latent Toxoplasmosis, Antonella Quimbayo
All HCAS Student Capstones, Theses, and Dissertations
Toxoplasma gondii is a prevalent parasite that infects about 30% of the world population. House cats and other felids serve as definitive hosts and acquire Toxoplasma by consuming infected prey, which are intermediate hosts. This includes rats and avians, but also large mammals such as wolves and deer. Toxoplasma gondii is known to manipulate prey behavior to enhance its transmission. For example, infected rodents demonstrates attraction to and curiosity around cat urine. Wolves infected with Toxoplasma were 11 times more likely to disperse from their pack and start a new pack. The manipulation of intermediate host behavior observed in rodents …
Differences In Stress Among Healthcare Workers In Rural And Urban Healthcare Settings--The Role Of Spirituality, Lisa Yancey
Differences In Stress Among Healthcare Workers In Rural And Urban Healthcare Settings--The Role Of Spirituality, Lisa Yancey
Doctoral Dissertations and Projects
In recent years, stress has become an unspoken epidemic that has affected many working adults. Many adults spend much of their waking hours working, contributing to their stress. This quantitative study examined the relationship between spirituality and stress among rural and urban healthcare workers. The data for this study was collected through social media platforms, email, and word of mouth. An online survey consisting of ten demographic questions, twenty questions from the Spiritual Well-Being Scale, and ten questions from the Perceived Stress Scale was administered to healthcare workers at least 18 years old through an anonymous survey. Pearson correlations were …
Waste Management Process And Malaria-Induced Child Mortality In Côte D’Ivoire., Kouame N'Guessan
Waste Management Process And Malaria-Induced Child Mortality In Côte D’Ivoire., Kouame N'Guessan
Walden Dissertations and Doctoral Studies
Malaria-induced child mortality is a Sub-Saharan African phenomenon, and Côte d'Ivoire, in West Africa, has one of the highest rates. This general qualitative study investigates waste management as a potential factor of malaria-induced child mortality to inform policy changes and fill a gap in the body of knowledge. The study is grounded in Skocpol's policy feedback theoretical framework. The research question explored aspects of waste management in Côte d'Ivoire which contribute to the high rate of malaria-induced child mortality. Eighteen participants, equally divided into three groups, were purposely recruited via email and WhatsApp messages for semi-structured interviews using a smartphone …
Analyzing The Message Complexity, Signal Words, And Readability Of Medical Tourism Warning Messages, Alicia Mason, Sakshi Bhati
Analyzing The Message Complexity, Signal Words, And Readability Of Medical Tourism Warning Messages, Alicia Mason, Sakshi Bhati
Faculty Submissions
Medical tourists are deemed to be a vulnerable patient population because they often have limited knowledge of the specialized health care treatment and services they seek. They are also frequently unfamiliar with the medical tourism physicians, providers, and facilitators with whom they interact. As a result, travel, biomedical, and procedural risks are often difficult to define and estimate. This analysis uses computer-automated technology to analyze the risk and warning messages distributed by government and private medical associations to medical tourists. Results show these messages are often complex and highly textual with little visual graphic elements. The messages frequently lack key …
No. 26: Pandemic Precarities And Remittance Narratives In The Global South, Jonathan Crush, Sujata Ramachandran
No. 26: Pandemic Precarities And Remittance Narratives In The Global South, Jonathan Crush, Sujata Ramachandran
Migration and Food Security (MiFOOD) Network
The COVID-19 pandemic has been referred to as a great disruptor of global migration leading to a crisis of immobility caused by public health lockdowns, closed borders, and the suspension of visa processing. Layoffs and retrenchments of migrant workers led to widespread hardship and an intensification of pre-pandemic precarity, as well as disrupted remittance channels and flows. Against this backdrop, the paper provides an overview of current debates about the relationship between COVID-19 and international migration in the context of South-South migration. We assess how pre-pandemic South-South migration flows were disrupted by the pandemic and the evidence for a crisis …
Relation Between The Negative Cognitive Triad, Perceived Everyday Discrimination, Depressive Symptoms, And Tnf-A In Adolescents., Ashley Ann Marshall Dondanville
Relation Between The Negative Cognitive Triad, Perceived Everyday Discrimination, Depressive Symptoms, And Tnf-A In Adolescents., Ashley Ann Marshall Dondanville
Electronic Theses and Dissertations
This study is based on Beck's cognitive stress-vulnerability model of depression and previous research on (a) the increased risk for severe illnesses associated with TNF-⍺ (i.e., an inflammatory cytokine), (b) the effect of perceived everyday discrimination (PED) on depressive symptoms and TNF-⍺, (c) the association between depressive symptoms and TNF-⍺, (d) and findings that the negative cognitive triad (i.e., negative views of the self, world, and future) serves as a partial mediator between PED and depressive symptoms. The purpose of this study is to integrate Beck’s model and these different research lines by inspecting the associations between the stressor PED …
Burma Refugees’ Migratory And Resettlement Experiences And Health Practices, Eunice E. Kim
Burma Refugees’ Migratory And Resettlement Experiences And Health Practices, Eunice E. Kim
Loma Linda University Electronic Theses, Dissertations & Projects
Many refugees from Burma (renamed Myanmar) resettled in the U.S. in recent years; however, they are largely unknown to the American public care system. This dissertation aimed to increase understanding of their unique existence and life trajectory and provide a groundwork to identify an effective way to assist their quest to secure health and well-being in their host communities. Guided by Max Weber's Interpretive Sociology and Ideal Type construct principles, this study investigated the Burma refugee’s particular sociodemographic characteristics, narratives of enduring refugee debilitating conditions across multiple contexts, and life adaptations. The sampled Burma refugees comprised 36 former and current …
Evolving Community Preparedness: Analysis Of United States Pandemic Health Disaster Readiness, Jessy Rugeyo
Evolving Community Preparedness: Analysis Of United States Pandemic Health Disaster Readiness, Jessy Rugeyo
Theses and Dissertations
The COVID-19 pandemic has shown substantial gaps in counties' preparedness and response capacity across the United States. This study analyzes the relationship between county-level pandemic preparedness and confirmed COVID-19 cases using secondary data from the FEMA's National Household Survey (NHS) and county-level COVID-19 data from the CDC. The data show a negative relationship between preparedness levels and COVID-19 positive rates, highlighting the necessity of proactive readiness measures. Individual risk assessment, motivation for preparedness, and socioeconomic variables have a major influence on confirmed cases. Higher levels of education, income, and preparedness are associated with lower positive rates, emphasizing the importance of …
A Comparison Of Maxent Models For Aedes Aegypti Species Distribution In South America Utilizing Different Bioclimatic And Environmental Variables, Matthew Beer
Electronic Theses and Dissertations
Aedes aegypti is the principal vector for dengue transmission across large areas of the world. Understanding where this critically important vector lives is paramount to preventing the continued expansion of dengue globally. Using 1981-2010 bioclimatic (bioclim) variables, as well as additional environmental variables and elevation data, multiple MaxEnt models were constructed for Ae. aegypti within the South American continent to identify ecologically important variables and areas of persistent high suitability. All models had acceptable AUC scores (> 0.70), indicating accurate model fitting. Annual mean precipitation and temperature were found to be important model variables; however, when added, humidity became the …
Mental Health Of Healthcare Workers In Kosovo During The Covid-19 Pandemic, Latif Hoxha
Mental Health Of Healthcare Workers In Kosovo During The Covid-19 Pandemic, Latif Hoxha
All Dissertations
ABSTRACT
This study explored the mental health of healthcare practitioners in Kosovo during the COVID-19 pandemic, focusing on the prevalence of stress, depression, and anxiety, and the associated individual, family, and work-related factors. The research employed a cross-sectional design with a sample of 449 healthcare workers from two hospitals in Kosovo. The Depression, Anxiety, and Stress Scale (DASS-21) was used to assess mental health symptoms, while socio-demographic and work-related information was collected through a questionnaire.
Based on the descriptive statistics of DASS-21 scores, the prevalence of mental health issues among the participants included high levels of depression (18%), anxiety (25%), …
Cyber Threats, Cyber Risks, And Cybersecurity Responses: Modeling Whole-Of-Nation Strategy Implementation For American Organizations And Citizens, Vincent Leon Guerrero
Cyber Threats, Cyber Risks, And Cybersecurity Responses: Modeling Whole-Of-Nation Strategy Implementation For American Organizations And Citizens, Vincent Leon Guerrero
All Dissertations
Amid a landscape of cyber attacks on America occurring below the threshold of armed conflict, strategic national policy efforts recommend a whole-of-nation approach where individuals and public and private organizations increase their defensive posture in cyberspace. Motivation to address the risk of a cyber event includes a continuum of cyber threats that can range from low-level disruptive events to cybercrime and cyber espionage to the possibility of a potentially catastrophic attack on critical infrastructure. In this dissertation, I conduct a survey experiment of various cyber threat conditions and cyber policies to model cybersecurity responses, risk perceptions to a possible cyber …
Cancer Care Terminology In African Languages, Hannah Simba, Miriam Mutebi, Moses Galukande, Yahya Mahamat-Saleh, Elom Aglago, Adamu Addissie, Lidya Genene Abebe, Justina Onwuka
Cancer Care Terminology In African Languages, Hannah Simba, Miriam Mutebi, Moses Galukande, Yahya Mahamat-Saleh, Elom Aglago, Adamu Addissie, Lidya Genene Abebe, Justina Onwuka
General Surgery, East Africa
Importance: Effective communication between patients and health care teams is essential in the health care setting for delivering optimal cancer care and increasing cancer awareness. While the significance of communication in health care is widely acknowledged, the topic is largely understudied within African settings.
Objective: To assess how the medical language of cancer and oncology translates into African languages and what these translations mean within their cultural context.
Design, etting, and participants: In this multinational survey study in Africa, health professionals, community health workers, researchers, and scientists involved in cancer care and research and traditional healers were invited to participate …
Dengue And Climate Change: Assessing Potential Future Areas Of Concern For Transmission In The United States, Matthew Beer
Dengue And Climate Change: Assessing Potential Future Areas Of Concern For Transmission In The United States, Matthew Beer
Electronic Theses and Dissertations
Background: Global climate change severely impacts human life, particularly health, as rising temperatures and extreme weather affect physical and mental well-being. Climate change can also alter the risk factors and epidemiology of infectious diseases, notably vector-borne diseases (VBDs), including those transmitted by mosquitoes. The Aedes mosquito, responsible for dengue, poses a significant threat due to its prevalence vector. Dengue prevention lacks effective methods beyond vector control, and the current vaccine has limitations, emphasizing the need for intensified research and prevention strategies to mitigate the expanding dengue burden worldwide. The goal of these studies was to establish a novel risk index …
Cognitive Behavioral Therapy Factors Related To Outcomes In Depression Among Youth With Hiv, Betsy D Kennard, Larry K Brown, Kristin Baltrusaitis, Miriam Chernoff, Graham J Emslie, Jessica Jones, Sarah Buisson, Jaime Deville, Megan Wilkins, Amber Bunch, Chivon Mcmullen Jackson, Christy Beneri, David E Shapiro
Cognitive Behavioral Therapy Factors Related To Outcomes In Depression Among Youth With Hiv, Betsy D Kennard, Larry K Brown, Kristin Baltrusaitis, Miriam Chernoff, Graham J Emslie, Jessica Jones, Sarah Buisson, Jaime Deville, Megan Wilkins, Amber Bunch, Chivon Mcmullen Jackson, Christy Beneri, David E Shapiro
Faculty, Staff and Students Publications
PURPOSE: This is a secondary analysis of a multi-site, cluster (site) randomized trial of the efficacy of a combined Health and Wellness Cognitive Behavior Therapy (H&W CBT) and medication management approach for depression in youth with HIV (YWH) compared to standard care. In this study, we explored the association between H&W CBT factors and depression outcomes after 24 weeks of treatment to discover treatment elements associated with symptom reduction.
METHODS: Participants (12-24 years of age) were YWH in the United States (US) diagnosed with moderate to severe depression [Quick Inventory of Depressive Symptomatology (QIDS), Clinician-Rated score ≥ 11]. Thirteen US …
New Approach To Mapping Regional Vulnerability In Controlling Tuberculosis Disease In Indonesia, Maria Holly Herawati, Asep Hermawan, Dasuki Dasuki, Hadi Supratikta, Al Asyary, M Rokhis Khomarudin, Muhammad Priyatna, Raflizar Raflizar, Kristina Kristina, Noer Endah Pracoyo, Dina Bisara, Cahya Tri Purnami, Mentari Nur Farida Suteja, Yusrial Bachtiar, Noor Edi Widya Sukoco, Doni Lasut
New Approach To Mapping Regional Vulnerability In Controlling Tuberculosis Disease In Indonesia, Maria Holly Herawati, Asep Hermawan, Dasuki Dasuki, Hadi Supratikta, Al Asyary, M Rokhis Khomarudin, Muhammad Priyatna, Raflizar Raflizar, Kristina Kristina, Noer Endah Pracoyo, Dina Bisara, Cahya Tri Purnami, Mentari Nur Farida Suteja, Yusrial Bachtiar, Noor Edi Widya Sukoco, Doni Lasut
Kesmas
Tuberculosis (TB) in Indonesia is still a health problem. The TB prevalence in Indonesia ranks second in the world after India in 2023. Regional factors, inadequate healthcare facilities, and limited resources (financial, human, and infrastructure) are challenges requiring innovation to help the government control TB. TB eradication efforts need to be made with a comprehensive and effective approach. One method used is to look at the vast territory of Indonesia, therefore, mapping the TB disease vulnerability is a highly recommended method. The use of a Geographic Information System is expected to help map the TB vulnerability areas in Indonesia. Given …
How Housing Insecurity And Welfare Systems Retraumatize Women In Southern California, Yesika Menera
How Housing Insecurity And Welfare Systems Retraumatize Women In Southern California, Yesika Menera
McNair Summer Research Program
Studies show that individuals experiencing homelessness and housing insecurity also experience trauma and mental illnesses. Despite this evidence, many resources provided through state welfare services seldom allocate sufficient funds and personnel to help address mental health. This study investigates the relationship between housing insecurity and trauma for adult women who have tried to access assistance throughout Southern California. To do this, I conducted in-depth interviews and DSM-5 questionnaires with twenty-six women during the summer of 2023 and 2024 via Zoom. My findings show that adult women who have experienced homelessness and housing insecurity in Southern California were more susceptible to …
Data Mining Analysis With Orange In The Development Of Tuberculosis Among Diabetes Mellitus Patients, Malahayati Rusli Bintang, Adang Bachtiar, Cicilya Candi
Data Mining Analysis With Orange In The Development Of Tuberculosis Among Diabetes Mellitus Patients, Malahayati Rusli Bintang, Adang Bachtiar, Cicilya Candi
Kesmas
Prevention and treatment of diabetes will have a positive influence on tuberculosis (TB) since people may get TB because they have diabetes mellitus (DM). Recording and reporting through the TB Information System are not run optimally because of many factors. The information system must be strengthened to be used by private health facilities. This study used secondary data from the 2013 and 2018 Indonesian Basic Health Research (IBHR). The data was analyzed univariately and analyzed further using Orange Data Mining Tools to test the screening tool model used to predict TB in diabetic individuals. The total sample in this study …
Smoking Habit At Home And Upper Respiratory Infection In Infants Aged 6-12 Months, Musfardi Rustam, Nur Pelita Sembiring, Taswir Effendy
Smoking Habit At Home And Upper Respiratory Infection In Infants Aged 6-12 Months, Musfardi Rustam, Nur Pelita Sembiring, Taswir Effendy
Kesmas
Upper Respiratory Tract Infection (URI) is an acute infection caused by viruses, fungi, and bacteria. Smoking habit at home is a risk factor for URI in infants. This study aimed to determine a relationship between smoking at home and the incidence of URI in infants. This study was conducted the fourth week of February 2010 until the third week of April 2010 in Kampar District, Indonesia. This analytical study used a case-control design and cluster random sampling. The samples comprised 162 cases and 162 controls, infants aged 6-12 months. The cases were 162 infants aged 6-12 months suffering from URI …
Modeling The Effect Of Human Behavior On Disease Transmission, Katie Yan
Modeling The Effect Of Human Behavior On Disease Transmission, Katie Yan
Rose-Hulman Undergraduate Mathematics Journal
Many infectious disease models build upon the classic Susceptible-Infected-Recovered (SIR) model, a compartmental system that is used to simulate disease transmission in a population. The SIR model focuses on the transmission of disease but rarely includes behavioral or informational components that explore how disease perception influences transmission. In this paper, we propose a six-compartment behavioral SIR model that further segments the classic SIR system based on knowledge of information about the disease, and we explore how sharing information affects disease transmission. We designate two states as aware and unaware based on whether the relevant information is known by the population. …
Identifying Driving Factors Of Inundation Susceptibility In Thailand With The Frequency Ratio Method, Zachary Zoet, Jim Wilson
Identifying Driving Factors Of Inundation Susceptibility In Thailand With The Frequency Ratio Method, Zachary Zoet, Jim Wilson
The Geographical Bulletin
Inundation models tend to cover geographically small areas at large-scales. Inconsistencies in research design arising from data classification methods and consensus about unit of analysis, and agreement on the choice of a consistent modeling method can lead to confusion in the selection of appropriate models for different inundation scenarios. To address these concerns, this study aims to expand on the Frequency Ratio Method, using 13 quantitative and qualitative variables, as a generalizable method that can be applied consistently across larger administrative areas such as the province. The ultimate product of this is a Flood Susceptibility Index (FSI), which can be …
Understanding The Roles Of Economy And Society In The Relative Risks Of Zoonosis Emergence From Livestock, Stephen Hinchcliffe, Alex Blanchette, Kin Wang (Ray) Chan, Chris Degeling, Jody Emel, Melissa Leach, Ian Scoones, Michael Winter
Understanding The Roles Of Economy And Society In The Relative Risks Of Zoonosis Emergence From Livestock, Stephen Hinchcliffe, Alex Blanchette, Kin Wang (Ray) Chan, Chris Degeling, Jody Emel, Melissa Leach, Ian Scoones, Michael Winter
Geography
The emergence of zoonotic infections that can develop into pathogens of pandemic potential is a major concern for public health. The risks of emergence and transmission relate to multiple factors that range from land use to human-non-human animal contacts. Livestock agriculture plays a potentially significant role in those risks, shaping landscapes and providing hosts that can act as the source or amplifiers of emergent pathogens. The relative risks will be contingent upon the nature of those systems, with comparisons often made between intensive, indoor, biosecure systems and more extensive, outdoor, insecure systems. Microbiological, ecological and veterinary sciences provide useful entry …
Impact Of Efavirenz On Hormone-Positive Breast Cancer Survival In Women Living With Hiv, Arthur T Johnson, Taolo Ntloedibe, Jose Euberto Mendez Reyes, Mogomotsi S Matshaba, Scott L Dryden-Peterson, Elizabeth Y Chiao
Impact Of Efavirenz On Hormone-Positive Breast Cancer Survival In Women Living With Hiv, Arthur T Johnson, Taolo Ntloedibe, Jose Euberto Mendez Reyes, Mogomotsi S Matshaba, Scott L Dryden-Peterson, Elizabeth Y Chiao
Center for Medical Ethics and Health Policy Staff Publications
Women living with HIV and breast cancer have poorer survival than HIV-negative women. Efavirenz-estrogen interactions are documented; however, the survival impact is unknown. Survival between women with estrogen-receptor positive breast cancer taking efavirenz (n = 38) and nonefavirenz regimens (n = 51) were compared. The 5-year overall-survival was 48.9% [95% confidence interval (CI) 33.0-72.2 and 51.1% (95% CI 34.0-76.8)] in the efavirenz and nonefavirenz groups, respectively suggesting efavirenz is unlikely driving poorer survival in women living with HIV and estrogen-receptor positive breast cancer.
Left Behind In Lockdown: Covid-19 And The Denver Unhoused Community, Lucy Briggs
Left Behind In Lockdown: Covid-19 And The Denver Unhoused Community, Lucy Briggs
The Geographical Bulletin
The population experiencing homelessness in Denver, Colorado, increased by nearly 15% from 2018 to 2019. This trend, combined with the SARS-CoV-2 (COVID-19) pandemic of 2020, led to a distinct crisis for unhoused communities. This research attempted to answer the question, “How has COVID-19 impacted the locational strategies and spatial patterns of the Denver unhoused population in relation to public spaces and resources in the city core?” More specifically, this research has three objectives: (1) To explore the impact of COVID-19 on the shelter availability in Denver, (2) to develop an understanding of COVID-19’s impact upon public restrooms in Denver, and …
Looking To The Past And Abroad To Enhance U.S. Presidential Debates, Jacob W. Justice, Talya P. Slaw, John Koch
Looking To The Past And Abroad To Enhance U.S. Presidential Debates, Jacob W. Justice, Talya P. Slaw, John Koch
Studies in Debate and Oratory
Presidential debates are a valuable, but flawed, method of educating voters about policy issues and candidates. Growing dissatisfaction with presidential debates, and polling evidence suggesting they are failing to inform audiences, creates exigence to reconsider the format of future debates. In this essay, we propose modifications to the format of United States presidential debates, in the interest of facilitating greater clash and audience education. To improve U.S. presidential debates, we draw upon two sources of inspiration: the history of U.S. presidential debates and international experiences with political debates. We recommend exploration of new debate formats that include (1) a narrow …
The Impact Of Clinical Genome Sequencing In A Global Population With Suspected Rare Genetic Disease, Erin Thorpe, Taylor Williams, Chad Shaw, Evgenii Chekalin, Julia Ortega, Keisha Robinson, Jason Button, Marilyn C Jones, Miguel Del Campo, Donald Basel, Julie Mccarrier, Laura Davis Keppen, Erin Royer, Romina Foster-Bonds, Milagros M Duenas-Roque, Nora Urraca, Kerri Bosfield, Chester W Brown, Holly Lydigsen, Henry J Mroczkowski, Jewell Ward, Fabio Sirchia, Elisa Giorgio, Keith Vaux, Hildegard Peña Salguero, Aimé Lumaka, Gerrye Mubungu, Prince Makay, Mamy Ngole, Prosper Tshilobo Lukusa, Adeline Vanderver, Kayla Muirhead, Omar Sherbini, Melissa D Lah, Katelynn Anderson, Jeny Bazalar-Montoya, Richard S Rodriguez, Mario Cornejo-Olivas, Karina Milla-Neyra, Marwan Shinawi, Pilar Magoulas, Duncan Henry, Kate Gibson, Samuel Wiafe, Parul Jayakar, Daria Salyakina, Diane Masser-Frye, Arturo Serize, Jorge E Perez, Alan Taylor, Shruti Shenbagam, Ahmad Abou Tayoun, Alka Malhotra, Maren Bennett, Vani Rajan, James Avecilla, Andrew Warren, Max Arseneault, Tasha Kalista, Ali Crawford, Subramanian S Ajay, Denise L Perry, John Belmont, Ryan J Taft
The Impact Of Clinical Genome Sequencing In A Global Population With Suspected Rare Genetic Disease, Erin Thorpe, Taylor Williams, Chad Shaw, Evgenii Chekalin, Julia Ortega, Keisha Robinson, Jason Button, Marilyn C Jones, Miguel Del Campo, Donald Basel, Julie Mccarrier, Laura Davis Keppen, Erin Royer, Romina Foster-Bonds, Milagros M Duenas-Roque, Nora Urraca, Kerri Bosfield, Chester W Brown, Holly Lydigsen, Henry J Mroczkowski, Jewell Ward, Fabio Sirchia, Elisa Giorgio, Keith Vaux, Hildegard Peña Salguero, Aimé Lumaka, Gerrye Mubungu, Prince Makay, Mamy Ngole, Prosper Tshilobo Lukusa, Adeline Vanderver, Kayla Muirhead, Omar Sherbini, Melissa D Lah, Katelynn Anderson, Jeny Bazalar-Montoya, Richard S Rodriguez, Mario Cornejo-Olivas, Karina Milla-Neyra, Marwan Shinawi, Pilar Magoulas, Duncan Henry, Kate Gibson, Samuel Wiafe, Parul Jayakar, Daria Salyakina, Diane Masser-Frye, Arturo Serize, Jorge E Perez, Alan Taylor, Shruti Shenbagam, Ahmad Abou Tayoun, Alka Malhotra, Maren Bennett, Vani Rajan, James Avecilla, Andrew Warren, Max Arseneault, Tasha Kalista, Ali Crawford, Subramanian S Ajay, Denise L Perry, John Belmont, Ryan J Taft
Center for Medical Ethics and Health Policy Staff Publications
There is mounting evidence of the value of clinical genome sequencing (cGS) in individuals with suspected rare genetic disease (RGD), but cGS performance and impact on clinical care in a diverse population drawn from both high-income countries (HICs) and low- and middle-income countries (LMICs) has not been investigated. The iHope program, a philanthropic cGS initiative, established a network of 24 clinical sites in eight countries through which it provided cGS to individuals with signs or symptoms of an RGD and constrained access to molecular testing. A total of 1,004 individuals (median age, 6.5 years; 53.5% male) with diverse ancestral backgrounds …