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Examining Age-Related Enhancement Of Multisensory Gain: The Role Of Sensory Decline And Inverse Effectiveness, Laura C. Schneeberger

Electronic Thesis and Dissertation Repository

Older adults experience a greater benefit from multisensory integration than their younger counterparts, but it is unclear why. One hypothesis is that age-related sensory decline weakens unisensory stimulus effectiveness, producing a boost in multisensory gain through inverse effectiveness. Many previous studies present stimuli at the same intensity for both younger and older adults (i.e., stimulus-matched), as opposed to accounting for each participant’s unique perceptual ability (i.e., perception-matched). This makes it difficult to discern the source of age-related differences in multisensory gain. Through a combination of stimulus-matched and perception-matched tasks, I found that older adults exhibit enhanced multisensory gain at low …

Investigating The Roles Of The Dorsal And Ventral Striatum In Humor Comprehension And Appreciation Throughout Health, Aging, And Parkinson’S Disease, Maggie Prenger

Electronic Thesis and Dissertation Repository

Humor processing is thought to involve two distinct components. The first, humor comprehension, involves detecting and resolving incongruities that are present within a humorous stimulus. This is related to cognitive processes such as ambiguity resolution, response inhibition, working memory, and cognitive flexibility, functions that are mediated in part by the dorsal portion of the striatum (DS). Humor appreciation, on the other hand, refers to the subjective amusement and mirth that one experiences in response to a joke. This is related to reward processing, which implicates the ventral portion of the striatum (VS). Across three separate studies, we investigated the involvement …

Changes In Audiovisual Integration In Aging, Alyssa S. Lynn

Undergraduate Student Research Internships Conference

The proposed study will examine changes in audiovisual integration between younger and older adults. Audiovisual integration enables us to associate and bind related auditory and visual information and experience it as a single percept (Spence, 2007). Being able to properly integrate is crucial in our everyday lives. When perceiving speech, audiovisual integration binds visual information from lip movements with auditory information from the speaker's utterances so that speech can be perceived multimodally. With age, our auditory and visual sensory acuity tends to decline with audiovisual integration being impacted as a result (Brooks et al., 2018; Mahoney et al., 2011). We …

The Coping Strategies Of Older Adults With Age Related Vision Loss (Arvl) – A Narrative Account, Zakara J. Stampp

Electronic Thesis and Dissertation Repository

The goal of this study was to share the stories of older adults with age-related vision loss (ARVL) and how they have coped to maintain meaningful occupational engagement. Grounded in a constructivist paradigm, data collection and analysis were guided by the narrative inquiry methodology. The participants consisted of six older adults aged 60 or older, diagnosed with one of the following ARVL conditions: macular degeneration, diabetic retinopathy, and/or glaucoma. Participants were recruited from vision loss non-profit organizations such as the Canadian National Institute for the Blind (CNIB) and the Alliance for Equity of Blind Canadians (AEBC). One older adult was …

Nursing Homes And Loneliness Among Older Adults In The United States, Camila Iciaszczyk

MA Research Paper

Many studies have revealed that older adults experience varying rates of loneliness depending on their living arrangements, yet few have been measured in nursing homes. I assess rates of loneliness among aging adults across different living arrangements, including nursing homes. Analyzing nationally representative longitudinal survey data from the United States, I observe older adults in all living arrangements and whether the transition into nursing homes is linked with increased rates of loneliness. Findings indicate that older adults living in nursing homes are at a 3.0 higher odds of experiencing loneliness compared to those living independently. When controlling for demographic and …

Neural Markers Of Musical Memory In Young And Older Adults, Avital Sternin

Electronic Thesis and Dissertation Repository

Memory for music can be preserved in the presence of neurodegenerative disorders even when other memories are forgotten. However, understanding how the brain remembers music has proven difficult despite decades of research. The central goal of this thesis was to elucidate the neural correlates of musical memory by exploring how the presence of language and music information affect the way young and older adults remember music. To that end, I 1) used a controlled training paradigm to familiarize participants with novel stimuli that manipulated the presence of language and music, and 2) collected functional magnetic resonance imaging data to compare …

Energy Access And Extreme Heat Events: A Case Study Of Seniors In Ottawa, Ontario, Samantha N. Doris

Electronic Thesis and Dissertation Repository

Energy poverty, or not having access to sufficient energy to meet one’s needs, is a serious problem in Canada and around the world. While the current literature on energy poverty largely focuses on the experiences of people utilizing energy services to stay warm during cold winter temperatures, little is known about experiences of energy poverty during summertime heat. This gap is especially urgent since current climate models suggest that cities are likely to experience extreme heat conditions more frequently in the future. This research investigates how people use energy services, such as air conditioning and fans, among other strategies to …

Social Isolation: Do Helpers Help Ward It Off?, Kirsten Young Brown

MA Research Paper

Social isolation is particularly relevant among elderly individuals who are more likely to need care and help with their physical and living needs. Little is known about whether receiving help correlates with social isolation in older adults living at home as often there is no focus from caregivers and helpers on older adults' social needs. Using data from the 2018 US National Health and Aging Trends Study, a sample of adults aged 65 plus on Medicare/Medicaid (N=4,321), I examine the relationship between social isolation and help. I estimate ordinary least squares regression models to test the association between receiving help …

The Relationship Between Theory Of Mind And Executive Function: Are They Two Facets Of The Same Process Or Two Distinct Processes?, Isu Cho

Electronic Thesis and Dissertation Repository

This dissertation examines the relationship between Theory of Mind (ToM) and Executive Function (EF). There has been debate on whether ToM and EF are two facets of the same process or are two distinct processes. Distinguishing between these possibilities empirically is challenging because the two abilities have similar developmental timetables and ToM tasks typically place high demands on EF, with the consequence that ToM and EF performance measures may be artificially correlated. Three experiments explored the nature of this relationship. Experiments 1 and 2 tested whether socio-cultural factors known to influence individual differences in EF (i.e., bilingualism, country-of-origin) extend to …

Thirty-Five Years Of Computerized Cognitive Assessment Of Aging — Where Are We Now?, Avital Sternin, Alistair Burns, Adrian M. Owen

Brain and Mind Institute Researchers' Publications

Over the past 35 years, the proliferation of technology and the advent of the internet have resulted in many reliable and easy to administer batteries for assessing cognitive function. These approaches have great potential for affecting how the health care system monitors and screens for cognitive changes in the aging population. Here, we review these new technologies with a specific emphasis on what they offer over and above traditional ‘paper-and-pencil’ approaches to assessing cognitive function. Key advantages include fully automated administration and scoring, the interpretation of individual scores within the context of thousands of normative data points, the inclusion of …

Moderating Effect Of Cortical Thickness On Bold Signal Variability Age-Related Changes, Daiana R. Pur, Roy A. Eagleson, Anik De Ribaupierre, Nathalie Mella, Sandrine De Ribaupierre

Brain and Mind Institute Researchers' Publications

© Copyright © 2019 Pur, Eagleson, de Ribaupierre, Mella and de Ribaupierre. The time course of neuroanatomical structural and functional measures across the lifespan is commonly reported in association with aging. Blood oxygen-level dependent signal variability, estimated using the standard deviation of the signal, or “BOLDSD,” is an emerging metric of variability in neural processing, and has been shown to be positively correlated with cognitive flexibility. Generally, BOLDSD is reported to decrease with aging, and is thought to reflect age-related cognitive decline. Additionally, it is well established that normative aging is associated with structural changes in brain regions, and that …

Longitudinal Alzheimer's Degeneration Reflects The Spatial Topography Of Cholinergic Basal Forebrain Projections, Taylor W. Schmitz, Marieke Mur, Meghmik Aghourian, Marc Andre Bedard, R. Nathan Spreng

Brain and Mind Institute Researchers' Publications

© 2018 The Author(s) The cholinergic neurons of the basal forebrain (BF) provide virtually all of the brain's cortical and amygdalar cholinergic input. They are particularly vulnerable to neuropathology in early Alzheimer's disease (AD) and may trigger the emergence of neuropathology in their cortico-amygdalar projection system through cholinergic denervation and trans-synaptic spreading of misfolded proteins. We examined whether longitudinal degeneration within the BF can explain longitudinal cortico-amygdalar degeneration in older human adults with abnormal cerebrospinal fluid biomarkers of AD neuropathology. We focused on two BF subregions, which are known to innervate cortico-amygdalar regions via two distinct macroscopic cholinergic projections. To …

Reading As A Lifeline Among Aging Readers, Paulette Rothbauer, Nicole Dalmer

FIMS Publications

No abstract provided.

Adolescent Cannabinoid Exposure Induces A Persistent Sub-Cortical Hyper-Dopaminergic State And Associated Molecular Adaptations In The Prefrontal Cortex., Justine Renard, Laura G Rosen, Michael Loureiro, Cleusa De Oliveira, Susanne Schmid, Walter J Rushlow, Steven R Laviolette

Brain and Mind Institute Researchers' Publications

Considerable evidence suggests that adolescent exposure to delta-9-tetrahydrocanabinol (THC), the psychoactive component in marijuana, increases the risk of developing schizophrenia-related symptoms in early adulthood. In the present study, we used a combination of behavioral and molecular analyses with in vivo neuronal electrophysiology to compare the long-term effects of adolescent versus adulthood THC exposure in rats. We report that adolescent, but not adult, THC exposure induces long-term neuropsychiatric-like phenotypes similar to those observed in clinical populations. Thus, adolescent THC exposure induced behavioral abnormalities resembling positive and negative schizophrenia-related endophenotypes and a state of neuronal hyperactivity in the mesocorticolimbic dopamine (DA) pathway. …

Category Learning In Older Adulthood: Understanding And Reducing Age-Related Deficits, Rahel R. Rabi

Electronic Thesis and Dissertation Repository

Executive functions are important for learning rule-based (RB) categories, as well as non-rule-based (NRB) categories (e.g., categories learned implicitly, without a verbal rule). However, executive functioning is known to decline with age, leading to age-related deficits in category learning. The current thesis examines RB and NRB category learning in older adults using category sets that vary in difficulty (e.g., rule complexity, number of stimulus dimensions, salience of stimulus dimensions). In Chapter 2, older adults and younger adults completed three category sets (simple single-dimensional RB, disjunctive RB, and NRB). Older adults learned the simple, single-dimensional rules quite well. In contrast to …

Enriching Or Discouraging? Competing Pictures Of Aging And Paid Work In Later Life, Rebecca Casey, Ellie Berger

Population Change and Lifecourse Strategic Knowledge Cluster Discussion Paper Series/ Un Réseau stratégique de connaissances Changements de population et parcours de vie Document de travail

The picture and experience of work and retirement are continuously changing in Canada and will likely continue to change into the future with the aging of the population. There are two pictures of work in older age presented in the literature: a positive and enriching picture and a picture that highlights the challenges facing some older workers. The positive and enriching picture focuses on the experiences of older individuals who are able to continue working if they want to work and are able to work; those who continue working because they are motivated by work rather than pay or new …

Research Brief No. 3 - Disability And Support Networks Of Older Canadians, Janice Keefe, Samuel Vézina, Jacques Légaré, Yann Décarie, Guillaume Lefrançois

Population Change and Lifecourse Strategic Knowledge Cluster Research/Policy Brief

The percentage of older Canadians requiring assistance with health-related tasks due to a long-term health condition increases sharply with age (Chen & Wilkins, 1998). As the first of the Boomers reach age 65 in 2011, it is of great interest to identify trends in disability and support network usage, to better predict future needs and resources within community care. This project used data from five national datasets to investigate the global disability rate and examine socio-demographic characteristics associated with disability and the use of informal and formal support networks to assist older adults with a health problem in performing everyday …

Category Learning In Older Adulthood: A Study Of The Shepard, Hovland, And Jenkins (1961) Tasks., Rahel Rabi, John Paul Minda

Brain and Mind Institute Researchers' Publications

Shepard, Hovland, and Jenkins (1961) examined the categorization abilities of younger adults using tasks involving single-dimensional rule learning, disjunctive rule learning, and family resemblance learning. The current study examined category learning in older adults using this well-known category set. Older adults, like younger adults, found category tasks with a single relevant dimension the easiest to learn. In contrast to younger adults, older adults found complex disjunctive rule-based categories harder to learn than family resemblance based categories. Disjunctive rule-based category learning appeared to be the most difficult for older adults to learn because this category set placed the heaviest demands on …

Living And Working Longer In An Aging Society: Toward Increasing Inequalities?, Yves Carrière, Jacques Légaré, Mélanie Léger St-Cyr, Chloé Ronteix, Viorela Diaconu

Population Change and Lifecourse Strategic Knowledge Cluster Discussion Paper Series/ Un Réseau stratégique de connaissances Changements de population et parcours de vie Document de travail

Population ageing raises questions about the sustainability of the public pillars of the retirement income system and about inter-generational equity. In response to this, a number of countries have raised the normal retirement age in an attempt to reduce projected future expenditures on their state pension system. In this context, private savings and later retirement represent the best ways of avoiding a major fall in living standards when retiring. Increased life expectancy at age 65 appears to justify this policy trend. But there are substantial differences in life expectancy and healthy life expectancy between people of different socio-economic status, and …

Effect Of Maternal Age On Offspring Social Behaviour In Drosophila Melanogaster, Shirley Long

2016 Undergraduate Awards

Aging can be defined as the natural and progressive decline in physiological functioning leading to increased risk for disease and death. Although the effects of age are well characterised, much less work has been done to study whether these detrimental changes can be transmitted to offspring. Advanced parental age has been correlated with higher incidence of neuropsychiatric disorders such as autism in children. As average maternal age increases in North America, it is becoming increasingly relevant to study the effects of maternal and paternal age on offspring social behaviour. We hypothesize that advanced maternal age in Drosophila melanogaster will affect …

Canada's Oldest Old: A Population Group Which Is Fast Growing, Poorly Apprehended And At Risk From Lack Of Appropriate Services, Jacques Légaré, Yann Décarie, Kim Deslandes, Yves Carrière

Population Change and Lifecourse Strategic Knowledge Cluster Discussion Paper Series/ Un Réseau stratégique de connaissances Changements de population et parcours de vie Document de travail

The future of population aging in industrialised countries, including Canada, will be driven not by lower fertility but by extensions in life expectancy. Declining mortality will have the most effect on the oldest age groups.

In this context, Peter Laslett’s (1989) ideas on rethinking traditional approaches to the life cycle are fundamental. He argues that we need to move from three stages of life to four: childhood; adulthood; then the new third age lasting from retirement until old age, which becomes the fourth age (or the oldest-old).

This report examines the present and future characteristics of the oldest old, and …

Fusion Analysis Of Functional Mri Data For Classification Of Individuals Based On Patterns Of Activation., Mahdi Ramezani, Purang Abolmaesumi, Kris Marble, Heather Trang, Ingrid Johnsrude

Brain and Mind Institute Researchers' Publications

Classification of individuals based on patterns of brain activity observed in functional MRI contrasts may be helpful for diagnosis of neurological disorders. Prior work for classification based on these patterns have primarily focused on using a single contrast, which does not take advantage of complementary information that may be available in multiple contrasts. Where multiple contrasts are used, the objective has been only to identify the joint, distinct brain activity patterns that differ between groups of subjects; not to use the information to classify individuals. Here, we use joint Independent Component Analysis (jICA) within a Support Vector Machine (SVM) classification …

Deficits In Audiovisual Speech Perception In Normal Aging Emerge At The Level Of Whole-Word Recognition., Ryan A Stevenson, Caitlin E Nelms, Sarah H Baum, Lilia Zurkovsky, Morgan D Barense, Paul A Newhouse, Mark T Wallace

Brain and Mind Institute Researchers' Publications

Over the next 2 decades, a dramatic shift in the demographics of society will take place, with a rapid growth in the population of older adults. One of the most common complaints with healthy aging is a decreased ability to successfully perceive speech, particularly in noisy environments. In such noisy environments, the presence of visual speech cues (i.e., lip movements) provide striking benefits for speech perception and comprehension, but previous research suggests that older adults gain less from such audiovisual integration than their younger peers. To determine at what processing level these behavioral differences arise in healthy-aging populations, we administered …

Stability Of Self-Referent Encoding Task Performance And Associations With Change In Depressive Symptoms From Early To Middle Childhood., Brandon L Goldstein, Elizabeth P Hayden, Daniel N Klein

Brain and Mind Institute Researchers' Publications

Depressed individuals exhibit memory biases on the self-referent encoding task (SRET), such that those with depression exhibit poorer recall of positive, and enhanced recall of negative, trait adjectives (referred to as positive and negative processing biases). However, it is unclear when SRET biases emerge, whether they are stable, and if biases predict, or are predicted by, depressive symptoms. To address this, a community sample of 434 children completed the SRET and a depressive symptoms measure at ages 6 and 9. Negative and positive processing exhibited low, but significant, stability. At ages 6 and 9, depressive symptoms correlated with higher negative, …

Older Woman Workers: Met And Unmet Needs For Health And Wellbeing In The Workplace, Gillian Gorfine

Electronic Thesis and Dissertation Repository

Older women workers report experiencing occupational injustices however the literature focuses on barriers faced rather than understanding the needs-based strategies empowering women as they age at work. This study engaged women aged 55 and older in a participatory action research project defining and examining strategies for older women workers’ health and wellbeing. In Phase 1, a key informant advisory group (N = 4) defined the problem and guided the design of an open answer survey conducted with 72 older women in work. Three categories emerged informing the fundamental, instrumental, and contextual needs of older women workers. Meeting fundamental needs may …

Return To Work After Retirement: Contributing Factors And Health Implications, Jason Settels

Electronic Thesis and Dissertation Repository

An issue of mounting importance in many industrialized nations, including Canada, is that of population aging. Because of fears that this trend could result in labour force shortages, many national governments and international organizations have encouraged policies aimed at prolonging the working life. This thesis builds on work that has been done to identify factors relevant to the likelihood of involvement in post-retirement work by examining how interactions among various demographic variables impact this likelihood. Furthermore, we investigated how post-retirement work is related to three measures of health and well-being. As well as confirming results obtained by others, we have …

Research Brief No. 1 - Social Inclusion Of The Oldest-Old: Toward Supportive Housing Policies, Judy Lynn Richards, Susan Sverdrup-Phillips, Jiangqin Du, Heather Maddocks, Heather Spiegel, Jennifer Brooks

Population Change and Lifecourse Strategic Knowledge Cluster Research/Policy Brief

Although most seniors aged 85+ live relatively independently in the community, research on this age group tends to focus on the negative aspects of aging. This study looks instead at seniors aged 85 and older who are living well and semi-independently in their communities with the help of an informal care provider. The study aims to identify the mechanisms that allow them to live with dignity and autonomy in their own homes and remain socially included in their communities. We conducted in-depth, semi-structured interviews with 16 individuals aged 85 to 94 years and their primary informal support-persons in Southwestern Ontario, …

Anosognosia In Mild Cognitive Impairment: Relationship To Activation Of Cortical Midline Structures Involved In Self-Appraisal, Michele L. Ries, Britta M. Jabbar, Taylor W. Schmitz, Mehul A. Trivedi, Carey E. Gleason, Cynthia M. Carlsson, Howard A. Rowley, Sanjay Asthana, Sterling C. Johnson

Brain and Mind Institute Researchers' Publications

Awareness of cognitive dysfunction shown by individuals with Mild Cognitive Impairment (MCI), a condition conferring risk for Alzheimer's disease (AD), is variable. Anosognosia, or unawareness of loss of function, is beginning to be recognized as an important clinical symptom of MCI. However, little is known about the brain substrates underlying this symptom. We hypothesized that MCI participants' activation of cortical midline structures (CMS) during self-appraisal would covary with level of insight into cognitive difficulties (indexed by a discrepancy score between patient and informant ratings of cognitive decline in each MCI participant). To address this hypothesis, we first compared 16 MCI …

Spirituality In Late Adulthood, Lisa M. Heintz, Imants Barušs

Psychology

MacDonald's Expressions of Spirituality Inventory was used to examine spirituality in late adulthood using a sample of 30 people (22 women, 8 men) whose mean age was 72.6 yr. While average scores are higher on scales measuring spiritual and religious beliefs and practices for the sample than for a standardization group of undergraduate students with a mean age of 21.0 yr., means are lower on scales measuring paranormal beliefs. Low scores on death anxiety are correlated only with Existential Well-being and age. And, while some religious behaviors such as frequent religious practice, prayer, and church attendance are correlated with some …