Digital Commons Network^™

Multi-Ancestry Genome-Wide Association Study Of Cannabis Use Disorder Yields Insight Into Disease Biology And Public Health Implications, Daniel F Levey, Marco Galimberti, Joseph D Deak, Frank R Wendt, Arjun Bhattacharya, Dora Koller, Kelly M Harrington, Rachel Quaden, Emma C Johnson, Priya Gupta, Mahantesh Biradar, Max Lam, Megan Cooke, Veera M Rajagopal, Stefany L L Empke, Hang Zhou, Yaira Z Nunez, Henry R Kranzler, Howard J Edenberg, Arpana Agrawal, Jordan W Smoller, Todd Lencz, David M Hougaard, Anders D Børglum, Ditte Demontis, Veterans Affairs Million Veteran Program, J Michael Gaziano, Michael J Gandal, Renato Polimanti, Murray B Stein, Joel Gelernter

Faculty, Staff and Student Publications

As recreational use of cannabis is being decriminalized in many places and medical use widely sanctioned, there are growing concerns about increases in cannabis use disorder (CanUD), which is associated with numerous medical comorbidities. Here we performed a genome-wide association study of CanUD in the Million Veteran Program (MVP), followed by meta-analysis in 1,054,365 individuals (ncases = 64,314) from four broad ancestries designated by the reference panel used for assignment (European n = 886,025, African n = 123,208, admixed American n = 38,289 and East Asian n = 6,843). Population-specific methods were applied to calculate single nucleotide polymorphism-based heritability within …

A Case Report Of Myocardial Infarction In A Young Transgender Man With Testosterone Therapy: Raising Awareness On Healthcare Issues In The Transgender Community And A Call For Further Research, Paul J Connelly, Joanna Osmanska, Matthew M Y Lee, Christian Delles, Margaret B Mcentegart, John Byrne

Faculty, Staff and Student Publications

BACKGROUND: People who are transgender may utilize masculinizing or feminizing gender-affirming hormonal therapy. Testosterone and oestrogen receptors are expressed throughout the cardiovascular system, yet the effects of these therapies on cardiovascular risk and outcomes are largely unknown. We report the case of a young transgender man with no discernible cardiovascular risk factors presenting with an acute coronary syndrome.

CASE SUMMARY: A 31-year-old transgender man utilizing intramuscular testosterone masculinizing gender-affirming hormonal therapy presented with central chest pain radiating to the left arm. He had no past medical history of hypertension, dyslipidaemia, diabetes, or smoking. Electrocardiography demonstrated infero-septal ST depression, and high-sensitivity …

Perceived Risks And Benefits Of Hpv Vaccination: The Role Of Cues To Action, Numeracy And, Literacy, Sierra Rae Galvan

Open Access Theses & Dissertations

Background & Significance: The Human Papillomavirus (HPV) is a risk factor for both genital warts and cervical cancer. HPV strains 16 and 18 are recognized as precursors of cervical cancer. While strains 6 and 11 are estimated to cause 90% of genital warts. Latinas have the highest rate of cervical cancer in the U.S, approximately 66 % higher than non-Latino whites. These cancers are preventable in many cases through the administration of the HPV vaccine. The advisory committee on immunization practices recommends that children as young as 9 receive at least two doses of the three-dose HPV vaccine series. Consequently, …

Exploring The Relationship Between Diabetes, Diabetes Risk, Depressive Symptoms, Chronic Stress, And Inflammatory Markers In Mexican-American Men, Aleli Fernandez

Open Access Theses & Dissertations

Background: Individuals with depression and stress are 60% more likely to develop type 2 diabetes compared to those without (Mezuk et al., 2008). Moreover, biological pro-inflammatory markers associated with psychosocial stress are risk factors for diabetes. Examining the relationship between psychological disorders, inflammation, and diabetes risk among MAH is important as they have high rates of diabetes.

Purpose: To examine the relationship between 1) depressive symptoms, chronic stress, and inflammatory markers, 2) inflammation and diabetes risk factors and 3) depression, stress, inflammation, diabetes risk, and metabolic syndrome (MetS).

Methods: A cross-sectional study of 100 adult men from El Paso, Texas …

Traditional And Emerging Modifiable Lifestyle Risk Behaviors For Non-Communicable Diseases In A Sample Of Hispanic/Latino American Adolescents Living In The U.S.-Mexico Border Region, Silvia Salinas Lopez

Open Access Theses & Dissertations

Background: Non-communicable diseases (NCDs) pose a significant global health threat, with modifiable lifestyle risk behaviors (mLRBs) contributing substantially to their onset. This study examined traditional and emerging mLRBs and their distribution on cross-sectional health outcomes among Hispanic/Latino in-school adolescents living on the U.S.-Mexico border. Methods: This secondary data analysis used information from the cross-sectional 2019 El Paso YHBS obtained through online surveys. The secondary data analyzed the prevalence, clustering, and co-occurrence of mLRBs of 539 Hispanic/Latino high school students. Results were compared to mLRBs findings corresponding to Hispanic/Latino adolescents who participated in the national and state 2019 CDC YRBSS. An …

The Impact Of Covid-19 On Managing Ophthalmic Diseases: An International, Descriptive Study, Ethan Waisberg, Joshua Ong, Nasif Zaman, Sharif Amit Kamran, Alireza Tavakkoli, Andrew G Lee

Faculty, Staff and Student Publications

Background: Anecdotally, the COVID-19 pandemic has resulted in more severe cases of eye disease, decreased medication compliance/availability, and decreased treatment volume due to the lockdown.

Aims: We aim to quantify and bring together a variety of international perspectives from ophthalmologists of different subspecialties to characterize the global impact of COVID-19 on managing various ophthalmic disease.

Methods: An online survey of 10 questions was conducted among ophthalmologists using a specialized survey program.

Results: Fifty-two ophthalmologists were successfully contacted. Survey respondents include ophthalmologists from USA, Canada, Korea, Mexico, and New Zealand. Based on the results of our survey, 1 year after the …

Effect Of The Announcement Of Human-To-Human Transmission On Teleconsultation Services In China During Covid-19, Mairehaba Maimaitiming, Jingui Xie, Zhichao Zheng, Yongjian Zhu

Research Collection Lee Kong Chian School Of Business

Objectives: Telemedicine enables patients to communicate with physicians effectively, especially during the coronavirus disease (COVID-19) pandemic. However, few studies have explored the use of online health care platforms for a comprehensive range of specialties during the COVID-19 pandemic. This study aimed to investigate how telemedicine services were affected by the announcement of human-to-human transmission in China. Methods: Telemedicine data from haodf.com in China were collected. A difference-in-differences analysis compared the number of telemedicine use and the number of active online physicians for different specialties in 2020 with the numbers in 2019, before and after the announcement of human-to-human transmission. Results: …

Access To A Regular Primary Care Physician Among Young People With Early Psychosis In Ontario, Canada, Rebecca Rodrigues, Jennifer N S Reid, Joshua C. Wiener, Suzanne Archie, Richard G Booth, Chiachen Cheng, Arlene G Macdougall, Lena Palaniyappan, Bridget L Ryan, Aristotle Voineskos, Paul Kurdyak, Saadia Hameed Jan, Kelly K. Anderson

Epidemiology and Biostatistics Publications

AIM: Access to a primary care physician in early psychosis facilitates help-seeking and engagement with psychiatric treatment. We examined access to a regular primary care physician in people with early psychosis, compared to the general population, and explored factors associated with access.

METHODS: Using linked health administrative data from Ontario (Canada), we identified people aged 14-35 years with a first diagnosis of nonaffective psychotic disorder (n = 39 449; 2005-2015). We matched cases to four randomly selected general population controls based on age, sex, neighbourhood, and index date (n = 157 796). We used modified Poisson regression to estimate prevalence …

Facility-Based Audit System With Integrated Community Engagement To Improve Maternal And Perinatal Health Outcomes In Rural Pakistan: Protocol For A Mixed Methods Implementation Study, Zahid Memon, Wardah Ahmed, Shah Muhammad, Sajid Bashir Soofi, Shanti Chohan, Arjumand Rizvi, Paul Barach, Zulfiqar Ahmed Bhutta

Centre of Excellence in Women and Child Health

Background: Maternal and newborn mortality in Pakistan remains as a major public health challenge. Pakistan faces significant infrastructure challenges and inadequate access to quality health care, exacerbated by sociocultural factors. Facility-based audit systems coupled with community engagement are key elements in achieving improved health system performance. We describe an implementation approach adapted from the World Health Organization audit cycle in real-world settings, with a plan to scale-up through mixed methods evaluation plan.
Objective: This study aims to implement a locally acceptable and relevant audit system and evaluate its feasibility within the rural health system of Pakistan for scale-up.
Methods: The …

Stigma And Mothers Using Opioids, Amelia Van Komen, Maren Wright Voss, Amy Campbell

All Current Publications

Parenting and pregnancy in the context of substance use is a complicated topic. Many public health officials, social workers, policy makers, and community members want to provide effective support and treatment for the child and for the parent. But when stigma, prejudice, or misinformation occur, parents who use substances can be exposed to added barriers to accessing care and support. This fact sheet addresses solutions to these barriers.

The Social Determinants Of Health And Genocide: Towards A Public Health Integrated Framework Of Genocide And Mass Violence, Sian Persad, Cheng Xu

Genocide Studies and Prevention: An International Journal

This paper makes a normative argument about transformations of public health as a necessary condition required in any transitional justice process. We seek to bridge the gap between the fields of genocide and public health to understand the recursive relationship between genocide and the social determinants of health. We show that structures and institutions established during genocide create enduring impacts on the public health outcomes of victim and survivor groups even after the ousting of the original perpetrators. Our comparative analysis of the Rwandan Genocide and the colonial genocide of Indigenous communities in Canada surveys the available public health literature …

Genetics Of Predicted Platelet Reactivity, Paul S De Vries

Faculty, Staff and Student Publications

No abstract provided.

Comparison Of Factors Responsible For The High Prevalence Of Pregnancy-Induced Hypertension, Maternal Death, And Preterm Birth Among Black Women In Washington, Dc And Massachusetts, Caroline Ohakwe

Walden Dissertations and Doctoral Studies

No abstract provided.

The Association Of Maternal Education, Income, And Race On Reduction Childhood Obesity, Ronell Michel

Walden Dissertations and Doctoral Studies

No abstract provided.

Editorial: The Public Health Scholars As The Health Leaders, Al Asyary, Meita Veruswati, Putri Bungsu Machmud, Indri Hapsari Susilowati

Kesmas

1. Achmadi UF. Kesehatan Masyarakat: Teori dan Aplikasi. Jakarta: Rajawali Pers; 2014.

2. Asyary A. Editorial. Kesmas. 2023; 18 (Special Issue 1): 1-3. DOI: 10.21109/kesmas.v18isp1.7201

3. Badan Kebijakan Pembangunan Kesehatan. Pembangunan Kesehatan di Indonesia melalui Kesinambungan Finansial Jaminan Kesehatan serta Meningkatkan Kualitas Layanan dengan Integrasi Data. Jakarta: Kementerian Kesehatan Republik Indonesia; 2023.

Evaluation Of Solid Medical Waste Management In Bogor Regional Public Hospitals, Silvia Khansa, Agustin Kusumayati, Dewi Susanna, Uli Tiarma Sinaga

Kesmas

Healthcare facilities generate medical waste. If not properly managed, medical waste may damage the environment and spread diseases. Many hospitals in Indonesia do not adhere to medical waste management regulations. This study aimed to evaluate the management of solid medical waste at four public hospitals in Bogor District, Indonesia. A case study design was used to obtain a comprehensive description of the solid medical waste management activities inthe hospitals. Data were collected through direct observations, interviews, and document reviews. This study revealed that the medical waste generated in allhospitals was infectious, pathological, pharmaceutical, chemical, and cytotoxic, totaling approximately 4,000-12,000 kg. …

Development And Validation Of Perception Of Seating Ergonomics Questionnaire: A Study On Klang Valley Drivers In Malaysia, Choy Min Yap, Hanif Farhan Mohd Rasdi, Dzalani Harun, Wen Xin Lim

Kesmas

Driving is an instrumental activity of daily living that has become an essential mode of transportation. Good ergonomic practices are vital to ensure successful driving. This study aimed to develop and validate a questionnaire that could be used to determine how personal, environmental, and occupational factors influence drivers' perceptions of seating ergonomics. This cross-sectional study was conducted in June-July 2022 among 250 drivers in the Klang Valley, Malaysia, recruited via an online survey. The participants completed the questionnaire by assessing different constructs in the Person-Environment-Occupationmodel and perceptions of seating ergonomics. Exploratory factor analysis (EFA) was conducted, followed by a path …

Development Of An Evidence-Based Tool To Assess The Relative Vulnerability Of Different Communities To Tuberculosis, Slamet Isworo, Sri Handayani, Reece Hinchcliff, Zainal Arifin Hasibuan

Kesmas

Identifying specific tuberculosis (TB) vulnerabilities in populations based on their geographical, demographic, and epidemiological characteristics is anessential yet challenging requirement to help reduce and eliminate TB. Assessment tools that can accurately quantify the risks associated with key factorscould be used to measure TB vulnerability efficiently and indicate the most appropriate range of interventions. This study aimed to develop TB vulnerability assessment tools based on a TB vulnerability assessment conceptual framework developed with Leximancer. Three steps to produce the tools were facetanalysis, interpreting the facet to create a list of questions, and expert judgment to confirm the suitability of the questionnaire. …

The Effect Of Fluid Overload Control Program On Knowledge And Behavior Among Caregivers Of End-Stage Renal Disease Patients On Hemodialysis, Kanyanat Ummee, Kittipan Rerkkasem, Jukkrit Wungrath

Kesmas

End-stage renal disease (ESRD) is a pressing health issue, and patients on hemodialysis frequently grapple with fluid overload. In Chiang Mai, Thailand, from September to November 2022, this study was conducted to assess the impact of an educational program on the knowledge and behavior of caregivers managing fluid overload in ESRD patients. Using a quasi-intervention design, participants were categorized into two groups: the intervention group, which underwent the educational intervention, and the control group, which continued with standard care. The educational content was grounded in existing studiesand insights from healthcare professionals, caregivers, and patients. Post-intervention results revealed a significant enhancement …

Role Of Partner And Health Workers On Modern Contraceptive Use Among Married/In-Union Women In Uzbekistan, Supriatin Supriatin, Mohamed Rifky, Muhammad Uzair Khan, Lili Amaliah, Marlynda Happy Nurmalita Sari, Eko Budi Santoso, Indra Ruswandi, Maretalinia Maretalinia, Linda Suwarni

Kesmas

Many factors contribute to the declining total fertility rate, including family planning programs. The successful implementation of the family planning method might be influenced by how the decision to choose a contraceptive method was made. This study aimed to examine the correlation between family planning decision-makers and modern contraceptive use among married/in-union women of reproductive age in Uzbekistan. The 2021-2022 Multiple Indicator Cluster Survey was used by selecting only married/in-union women of reproductive age of 15 to 49 years, totaling 2,794 eligible samples. The modern family planning use variables were divided into not using, using Long-Acting Contraceptives (LAC), and Short-Acting …

System Safety Assessment Of The Warehouse Operation Using Functional Resonance Analysis Method And Resilience Analysis Grid, Adithya Sudiarno, Ahmad Murtaja Dzaky Ma’Arij

Kesmas

This study applied the perspective of Safety-II using the Functional Resonance Analysis Method (FRAM) and the Resilience Analysis Grid (RAG) to analyze safety in warehouse operations from a system perspective. FRAM was used to emphasize what caused things to go right, with the findings highlighting higher performance and safety variability occurring in activities that require multiple individual or group efforts. RAG was used to assess the organization’s potentialto handle unexpected occurrences, identify the potential resilience of the warehouse in its daily activities, and evaluate the ability to maintain flow and workersafety based on four pillars of resilience. The assessment resulted …

Social Media Use Behavior And Social Media Disorder Among Faculty Of Public Health Students During The Covid-19 Pandemic, Tiara Amelia, Ulfi Hida Zainita, Evi Martha

Kesmas

Excessive use of social media can lead to vulnerability to social media disorder, which is significantly related to the trend of mental health problems among college students. This study aimed to assess the prevalence of social media disorder among college students and to determine the relationship between the number of social media accounts, the total duration of social media use, and social media disorder. This cross-sectional study collected data through an online survey of 201 college students from the class of 2021 in the Faculty of Public Health, Universitas Indonesia. This study used the Social Media Disorder scaleand univariate and …

Data Quality Checks: Implementation With Popular Data Collection Crowdsourcing Platforms, James Down, Gregory Balkcom, Kristine Duncan, Ngan (An) Truong, Andrew Lewis

Symposium of Student Scholars

The utilization of online crowdsourcing platforms for data collection has increased over the past two decades in the field of public health due to the ease of use, the cost-saving benefits, the speed of the data collection process, and the accessibility of a potentially true representative population. Although these platforms offer many advantages to researchers, significant drawbacks exist, such as poor data quality, that threaten the reliability and validity of the study. Previous studies have examined data quality concerns, but differences in results arise due to variations in study designs, disciplinary contexts, and the platforms being investigated. Therefore, this study …

Spatial Associations Of Liver Disease Rates With Socioeconomic And Health Risk Factors In Georgia, Nguyet Le

Symposium of Student Scholars

According to the CDC Cancer Statistics Report in 2020, Liver and Intrahepatic Bile Duct is the 6th leading cancer in both USA and the State of Georgia ranked by Rates of Cancer Death. Aflatoxin-containing foods, alcohol consumption, smoking, overeating, and other risky behaviors are among the factors linked to liver diseases. They have also been related to the socioeconomic status (SES) of individuals. The behaviors and SES of individuals are affected by the socioeconomic characteristics of the communities where they live. However, the relationships between the rates of liver diseases and community-level socioeconomic factors are not well studied. The objective …

Exploration Of The Implementation Of An Integrated Electronic Laboratory Information Management System On Quality Diagnostics Service Indicators At A County Level Public Hospital In Western Kenya., Kelly Allen

Capstone Collection

Underinvestment in pathology and laboratory capacity caused by low visibility in research and in prioritization by public health leaders results in limited effective healthcare coverage and an estimated 1.1 million premature deaths annually in Low-and-Middle-Income Countries. Kenya’s public health laboratories provide a median 41% of the Essential Diagnostic List to their patients and in Kisumu County, as much as 44.2% of the population has little to no access to essential diagnostics. The government of Kisumu implemented the county Health Laboratory Strategic Plan 2018-2022 to address this public health challenge. Little information exists on the effectiveness of these initiatives and the …

South Los Angeles Park Observation Research, Valeria N. Delgado, Melissa R. Ramos

Student Scholar Symposium Abstracts and Posters

The health impact of elevated gang activity on the residents of South Los Angeles has been a pressing concern with limited research. Thus, this study aimed to understand the potential health repercussions within this context, specifically by examining how different patrolling systems influence community members' physical activity in public parks. To increase security, the city of Los Angeles implemented police patrol programs in multiple high-risk parks. Concurrently, the Advocates for Urban Peace & Unity (APUU), a local community organization, introduced a novel approach of community-led park patrolling. Essentially, respected community members volunteer to patrol and maintain safety and order in …

Latinx Social Work Students’ Well-Being Prior To And During The Covid-19 Pandemic, Leyla Feize

School of Social Work Faculty Publications

This is a reflection on social work students’ well-being before and during the COVID-19 pandemic. This narrative was indirectly written by the students, as it is their interpretations of their feelings, thoughts, and behaviors derived from drawing their own mandalas daily for one month. It is a comparison of two stories of struggle, hope, and change during two different periods which were close in time, but far in reality.

Empowering The Community: An Explanatory Mixed Methods Study Exploring The Social Mechanisms Of Community Health Worker-Primary Care Integration Using A Team Science Approach, Alexandria Blacker

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: Expanding primary care (PC) has emerged as a national priority to transform health care delivery (Pittman et al., 2015). This requires that PC teams become highly functioning interprofessional teams. Community Health Workers (CHWs), frontline health care workers who are seen as trusted members of their community, act as links between the community and care teams, providing a crucial means to increase access to health services, reduce health care costs and address social determinants of health (SDH) (American Public Health Association, 2021). CHWs are increasingly becoming part of PC teams (Franklin et al., 2015; Herman, 2011). Despite decades of research …

Examining Factors Associated With Covid-19 Full Vaccination Rates Among Healthcare Workers, Carrie Jeanne Vanzant

Walden Dissertations and Doctoral Studies

No abstract provided.

Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole

Journal of Health Disparities Research and Practice

Due to the underutilization of screening mammography, African American women (AAW) are more likely to experience negative health outcomes after receiving a late-stage breast cancer diagnosis than White Women (WW). The purpose of this article is to examine the roles of the media, health community and the African American church and pastor and their potential impact in AAW screening decisions. Fifteen AAW, ages 45 and older, were invited to participate in a semi-structured interview. Most women agreed the African American pastor and church as well as the health community, and media are an integral part of their lives. Therefore, specific …