Diagnostic Excellence In The Context Of Climate Change: A Review, Kisha J Ali, Sara Ehsan, Alberta Tran, Monika Haugstetter, Hardeep Singh

Faculty, Staff and Students Publications

Climate change is leading to a rise in heat-related illnesses, vector-borne diseases, and numerous negative impacts on patients' physical and mental health outcomes. Concurrently, healthcare contributes about 4.6% of global greenhouse gas emissions. Low-value care, such as overtesting and overdiagnosis, contributes to unnecessary emissions. In this review, we describe diagnostic excellence in the context of climate change and focus on two topics. First, climate change is affecting health, leading to the emergence of certain diseases, some of which are new, while others are increasing in prevalence and/or becoming more widespread. These conditions will require timely and accurate diagnosis by clinicians …

Natural History Of Indeterminate Liver Nodules In Patients With Advanced Liver Disease: A Multicenter Retrospective Cohort Study, Amit G Singal, Neehar D Parikh, Kirti Shetty, Steven-Huy Han, Cassie Xie, Jing Ning, Jo Ann Rinaudo, Ashwini Arvind, Anna S Lok, Fasiha Kanwal, Translational Liver Cancer Investigators

Faculty, Staff and Students Publications

Introduction: Indeterminate liver nodules (ILNs) are frequently encountered on diagnostic imaging after positive hepatocellular carcinoma (HCC) surveillance results, but their natural history remains unclear.

Methods: We conducted a multicenter retrospective cohort study among patients with ≥1 newly detected LI-RADS 3 (LR-3) lesion ≥1 cm or LI-RADS 4 (LR-4) lesion of any size (per LI-RADS v2018) between January 2018 and December 2019. Patients were followed with repeat imaging at each site per institutional standard of care. Multivariable Fine-Gray models were used to evaluate associations between potential risk factors and patient-level time-to-HCC diagnosis, with death and liver transplantation as competing risks.

Results: …

Asn Kidney Health Guidance On The Management Of Obesity In Persons Living With Kidney Diseases, T Alp Ikizler, Holly J Kramer, Srinivasan Beddhu, Alex R Chang, Allon N Friedman, Meera N Harhay, Elizabeth Yakes Jimenez, Brandon Kistler, Aleksandra Kukla, Kristin Larson, Lindamarie U Lavenburg, Sankar Dass Navaneethan, John Ortiz, Rocio I Pereira, David B Sarwer, Philip R Schauer, Evan M Zeitler

Faculty, Staff and Students Publications

No abstract provided.

Access To Treatment For Chronic Obstructive Pulmonary Disease In The Americas: A Call For Action A Joint Perspective From The Brazilian Thoracic Society, Canadian Thoracic Society, Latin American Thoracic Society, And The American Thoracic Society, Francesca Polverino, Mohit Bhutani, Gustavo Zabert, Frederico Leon Arrabal Fernandes, Karen Czischke, Luiz Fernando Pereira Ferreira, Lian Szabo, Juan P Wisnivesky, Margareth Pretti Dalcolmo, Juan C Celedón

Faculty, Staff and Students Publications

Chronic obstructive pulmonary disease (COPD) is a major public health problem in the Americas (a region of the world comprising North, Central, and South America), although there is substantial variation in disease prevalence, morbidity, and mortality between and within nations. Across the Americas, COPD disproportionately affects vulnerable populations, including minoritized populations and impoverished persons, who are more likely to be exposed to risk factors such as tobacco use, air pollution, infections such as tuberculosis, and biomass smoke, but less likely to have adequate healthcare access. Management of COPD can be challenging across the Americas, with some barriers being specific to …

Exploring The Air Pollution With Particulate Matter - Pm10, Covid-19 Cases Evolution In Romania And Exposure To Aeroallergens, Irina Mihaela Stoian, Simona Parvu, Radu Cucuiu, Dana Galieta Minca

Journal of Mind and Medical Sciences

Constant exposure to the atmospheric air polluted with particulate matter is considered to have a negative influence on human health, even if it is found at values that may not exceed the maximum allowable concentration. Starting from the correlation between atmospheric air polluted with PM and COVID-19 incidence/mortality, this research had as first objective to assess the exposure to an average concentration of PM10 in Romania and, in particular, in Bucharest for a period of six years and the cumulative incidence of COVID-19 cases per 1000 inhabitants (continuing previous research, from 2020). Subsequently, we studied the cumulative incidence of COVID-19 …

Assessment Of The Bioaccumulation Of Nicotine And Cotinine By The Crustacean Daphnia Magna, Ana Maria Vlasceanu, Daniela Luiza Baconi, Octavian Tudorel Olaru, Daniela Grădinaru, Viorela Gabriela Nitescu

Journal of Mind and Medical Sciences

Objectives. This study aimed to investigate the toxicity of nicotine and its metabolite cotinine on crustacean D. magna, and evaluate the quantity of compounds accumulated by D. magna. Materials and Methods. The bioassays involved the exposure of D. magna to varying doses of nicotine and cotinine, for 24 h and 48 h. The amount of bioaccumulated nicotine and cotinine was determined by an HPLC-DAD method. Results. The study has revealed that nicotine is more toxic than cotinine on D. magna, as the medium lethal concentration (LC50) values were higher for nicotine compared to cotinine. After 24 hours of exposure, D. …

Hepatotoxicity Induced By Immune Checkpoint Inhibitors, Flaviu Muresan, Olga Hilda Orasan, Angela Cozma, Madalina Daiana Bancos, Lorena Ciumarnean, Mircea Vasile Milaciu, Tinca Codruta Pocol, Nicoleta Valentina Leach, Teodora Gabriela Alexescu, Ovidiu Vasile Fabian, George Ciulei, Mirela Georgiana Perne

Journal of Mind and Medical Sciences

Immune checkpoint inhibitors (ICIs) are an effective immunotherapeutic approach for cancers affecting the lung, skin, kidney, mammary gland, or certain hematologic malignancies. Regarding the prognosis of these oncological conditions, treatments with ICIs open new therapeutic perspectives with benefits for both patients and healthcare providers. A drawback of immune checkpoint inhibition is the occurrence of immune-related adverse events that can involve a wide range of organs, such as the liver. Given widespread usage of immunotherapy, the number of patients who suffer from this unwanted condition has increased. Hepatopathy induced by ICIs can be severe and can even lead to death. Detecting …

Enhancing Patient Safety: The Role Of Interdisciplinary Teams In Reducing Blood Culture Contamination, Austin Patrick Eisenberg, Fady M. Awad, Brian Watson, Mohammed Faris

HCA Healthcare Journal of Medicine

Background

Blood cultures are vital to diagnostic workups among many hospitalized patients, providing valuable information about bloodstream infections (BSIs), which cause roughly 250 000 deaths annually between North America and Europe. Despite advances in health care, blood culture contamination remains a substantial problem, with deleterious effects on patient mortality, patient and hospital costs, and microbial resistance. This article reviews the repercussions of blood culture contamination on the health care system and delineates evidence-based strategies to decrease contamination rates.

Methods

To reduce blood culture contamination rates, our health care facility undertook a quality improvement initiative. A task force was created, consisting …

Inpatient Falls: Epidemiology, Risk Assessment, And Prevention Measures. A Narrative Review, Taylor Locklear, Jeannie Kontos, Callaham A. Brock, Alexander B. Holland, Rachel Hemsath, Anna Deal, Shannon Leonard, Carsten Steinmetz, Saptarshi Biswas

HCA Healthcare Journal of Medicine

Patient falls are a common inpatient dilemma and comprise the largest category of preventable adverse events in hospitalized patients. These events place a clinical burden on the patient, such as increased morbidity and reduced quality of life, in addition to an economic burden on the hospital system. Fall prevention strategies have the opportunity to decrease inpatient health care costs and length of stay. Several risk factors have been identified that contribute to inpatient falls and several strategies have been identified to minimize this risk. These risk factors are typically characterized as intrinsic and extrinsic factors. Intrinsic factors include characteristics such …

Hospital Readiness To Implement Electronic Medical Records: A Systematic Literature Review, Afni Fatmasari, Mardiati Nadjib

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Implementing electronic medical records (EMR) in hospitals can increase the efficiency and effectiveness of health services. However, hospitals' readiness to adopt this technology is influenced by various complex factors. This study aims to identify factors that affect hospital readiness in implementing EMR through a systematic literature review (SLR). The SLR process followed the PRISMA method and included a literature search from Scopus, PubMed, and Cochrane databases with keywords related to RME readiness, which yielded 412 articles. After the screening and eligibility stages, 19 articles were selected for further analysis. The findings of this research identify readiness factors based on the …

Kajian Risiko Kesehatan Terkait Pajanan Benzene, Toluene Dan Xylene Pada Pekerja Kilang Minyak Pt. X, Putri Noer Halizah, Mila Tejamaya

National Journal of Occupational Health and Safety

Workers in oil and gas production units are at risk of exposure to chemical hazards. One of the ingredients in petroleum is volatile organic compounds (VOC), with examples of ingredients known for their toxicity being benzene, toluene and xylene. This study aims to assess health risks related to exposure to benzene, toluene and xylene of oil refinery workers at PT. X. This study will analyze personal exposure to inhalation routes from benzene, toluene and xylene chemicals using the Chemical Health Risk Assessment (CHRA) method from the Department of Safety and Health, Malaysia. The study results showed that the risk level …

How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.

Faculty Publications

Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research. Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL. Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …

Analysis Of Continuous Ambulatory Peritoneal Dialysis Service Readiness At Rsud Kota Bogor In 2023, Ni Nyoman Diah Redyardani, Dumilah Ayuningtyas

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The availability of health service facilities certainly contributes to one of the success factors in the distribution of health services in Indonesia, including renal replacement therapy (RRT) services. Through Minister of Health Regulation (PMK) No. 8 of 2022, the government ensures that patients with end-stage renal disease (ESRD) receive equal access to RRT. One of the efforts to equalize dialysis services is implementing Continuous Ambulatory Peritoneal Dialysis (CAPD) services. Therefore, RSUD Kota Bogor must prepare for CAPD services in its dialysis installations. This research analyzes the readiness and efforts to provide CAPD services at RSUD Kota Bogor. This study employs …

Length Of Stay Di Instalasi Gawat Darurat Sebagai Indikator Mutu Pelayanan Kesehatan Di Rumah Sakit X Tahun 2024, Gustiane Adriani Dwisari, Kurnia Sari

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The Emergency Department (ED) is crucial for ensuring patient care and safety in hospitals. A key performance indicator is Length of Stay (LOS), where prolonged LOS can lead to overcrowding, increase the risk of adverse events, and lower patient satisfaction. This study examines the service flow, barriers, and root causes of LOS in Hospital X's ED and provides improvement recommendations. Data were gathered through observation of 30 patients, interviews, and document reviews. Lean Thinking principles and the BAS method from BASICS (Baseline, Assess, Suggest Solution, Implement, Check Result, Sustain) were used in the analysis, employing flowcharts to map the process, …

Rencana Strategis Peningkatan Kinerja Poliklinik Eksekutif Rumah Sakit X Tahun 2024 -2027: Pendekatan Balanced Scorecard, Irfan Rohot Uli Manik, Adang Bachtiar

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Hospital X is a private hospital that has executive polyclinic services. Medical record data shows that in the last four years, the number of visits from the executive polyclinic unit has never reached the target set. This research is to prepare the strategic plan for improving the executive polyclinic of Hospital X's performance for 2024-2027. The types of data in this research are primary data and secondary data. Primary data is qualitative data from in-depth interviews, Consensus Decision Making Group (CDMG) with informants, and direct observation. Secondary data consists of quantitative data and qualitative data. Strategy implementation will be described …

Faktor Yang Berhubungan Pada Motivasi Pengguna Dan Implementasi Rekam Medis Elektronik Dengan Efisiensi Pelayanan Di Instalasi Rawat Jalan Rsud Kebayoran Lama, Jean Francis Melanny Kassiuw, Budi Hidayat

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Electronic Medical Records (EMR) have emerged as an innovative solution in healthcare because EMR offers several advantages and provides a comprehensive solution to improve health information management in today’s digital era. This study applies the Technology Acceptance Model (TAM) as its theoretical foundation, aiming to evaluate the relationship between user perceptions of key factors influencing EMR implementation and service efficiency in the Kebayoran Lama Regional Hospital outpatient unit. The research design is non-experimental with a quantitative approach, utilizing numerical data analyzed through Structural Equation Modeling (SEM). The study collected data on user perceptions regarding EMR implementation and service efficiency through …

Hubungan Tingkat Risiko Postur Kerja Dan Faktor Individu Dengan Keluhan Musculoskeletal Disorders Pekerja Mebel Tunjungsekar, Aquila Ghafril Azizah, Mochamad Yusuf, Anita Sulistyorini, Agung Kurniawan

National Journal of Occupational Health and Safety

The high poverty rate in Indonesia can be addressed through the contribution of Micro, Small, and Medium Enterprises (MSMEs), which absorb approximately 57.78% of the workforce in the informal sector. However, this sector faces risks of workplace accidents and occupational diseases that can impact workers' productivity and well-being. Musculoskeletal Disorders (MSDs) account for 42% to 58% of all recorded occupational diseases globally. Preliminary observations identified symptoms of MSDs, such as neck stiffness and back pain, among furniture workers in the informal sector of Tunjungsekar. This study aims to determine the relationship between the risk levels of work posture and individual …

Manajemen Rumah Sakit Dalam Kesiapsiagaan Menghadapi Bencana Di Rsud Balaraja: Metode Hospital Safety Index, Puspita Gaharu Nisaa, Robiana Modjo

National Journal of Occupational Health and Safety

Hospitals are required to provide health services under disaster conditions, serving as the front line to help survivors and patients. RSUD Balaraja of Tangerang Regency, the only Type B hospital owned by the Regency Government, is exposed to high potential disaster hazards, including floods, extreme waves, abrasions and tsunamis, as well as moderate risk of earthquakes. This study aims to analyse hospital management in disaster preparedness using a cross-sectional design with quantitative and qualitative approaches through Module 4 of the Hospital Safety Index and a phenomenological approach. The results showed that hospital management was rated as moderately safe in disaster …

Gambaran Persepsi Pengawas Terhadap Efektivitas Geotab Dalam Mengendalikan Risiko Kecelakaan Kendaraan Ringan Di Divisi X, Aisyah Yasmin Zafirah, Chandra Satrya

National Journal of Occupational Health and Safety

This study aims to understand supervisors' perceptions of the effectiveness of Geotab as a control measure for mitigating the risk of collisions involving light vehicles. Conducted in Division X of PT. X, a mining industry, from February to June 2023, this descriptive, semi-qualitative study collected data through control effectiveness questionnaires, interviews, and document review. The variables studied include the relevance, coverage, reliability, reactivity, resource competence, and supervision system of Geotab. Questionnaire results showed supervisor perception scores of 3.09 for relevance (appropriate), 3.10 for coverage (appropriate), 3.06 for reliability (appropriate), 2.99 for reactivity (appropriate), 2.93 for resource competence, and 2.95 for …

The Relationship Between Snacking And Sugar, Salt, Fat Intake On Nutritional Status Of Adolescents Of Smkn 30 Jakarta, Khoirul Anwar, Syifa Aulia Putri

Indonesian Journal of Public Health Nutrition (IJPHN)

Excessive consumption of sugar, salt, and fat including from snacks can increase the risk of obesity or being overweight. The objective of this study to analyze the relationship between snacking and sugar, salt, and fat intake on nutritional status in adolescents. This design is cross-sectional with a sample of 90 grade X students at SMKN 30 Jakarta. The data collected include physical activity data using the Global Physical Activity Questionnaire (GPAQ), snacking habit data, frequency of sugar, salt, and fat consumption using the SQ-FFQ. The results of the correlation test showed that there was a significant relationship between snacking habits …

Factors Related To The Consumption Of Sugar-Sweetened Beverages (Ssbs) Among High School Students At Sma Negeri 68 Jakarta In 2024, Debora Karyoko, Wahyu Kurnia Yusrin Putra, Teguh Jati Prasetyo

Indonesian Journal of Public Health Nutrition (IJPHN)

Indonesia ranked third in Southeast Asia for Sugar-Sweetened Beverages (SSBs) consumption in 2022, with a consumption rate of 20.23 liters/person/year. According to Riskesdas in 2018, 61.3% of the Indonesian population consumed more than once a day and 47.5% in 2023. This study aims to understand the patterns and levels of SSB consumption among various factors in students of SMA Negeri 68 Jakarta in 2024. This cross-sectional study was conducted from April to May 2024 with 134 respondents using questionnaires and interviews for 24-hour food recall and SQ-FFQ. Univariate analysis showed that 12.69% of respondents had high SSB consumption. Bivariate analysis …

Home And Community-Based Case Manager Job Satisfaction During The Covid-19 Public Health Emergency, Timothy Frederick Conroy

Walden Dissertations and Doctoral Studies

There is limited information on the impact on Home and Community-Based Services (HCBS) case managers’ job satisfaction as COVID-19 policies altered the way their jobs were performed. Many HCBS case managers in the United States experience high levels of turnover and burnout, resulting in difficulty maintaining appropriate service levels. Public health emergency (PHE) policies used to limit exposure of high-risk community-based individuals to COVID-19 resulted in various adjustments to traditional job responsibilities. The purpose of this research was to qualitatively study the impact of HCBS policy changes on the job satisfaction of HCBS case managers prior to and throughout the …

The Relationship Of Dietary Pattern And Physical Activity On Cholesterol Level In Young Adults, Wahyuni Sammeng

Indonesian Journal of Public Health Nutrition (IJPHN)

High blood cholesterol levels are a serious problem because they are one of the risk factors for degenerative diseases such as cardiovascular. Research data shows that in Ambon City, 32.49% of the population has the habit of consuming fatty/cholesterol/fried foods ≥1 time per day. The purpose of this study was to determine the relationship between dietary habit and physical activity with blood cholesterol levels. The type of research used was quantitative, sampling technique used was convenience sampling for 30 people. The independent variables in this study were dietary intake (amount, frequency, and type) measured using a semi-quantitative FFQ and physical …

Different Food Coping Strategies In Urban And Semi-Urban Areas During Coronavirus Disease 2019 (Covid-19) Pandemic, Sandra Fikawati, Ahmad Syafiq, Rizna Notarianti, Syilga Cahya Gemily

Indonesian Journal of Public Health Nutrition (IJPHN)

Consumption-related behavior implemented as an effort to maintain household food security is referred to as a food coping strategy (FCS). This study aims to describe the selection of FCS by families in urban and semi-urban areas in Indonesia during the COVID-19 pandemic. This research is a cross-sectional study with a total sample of 517 people who live in urban (Jakarta) and semi-urban (Depok) areas. The research data was taken from primary research data that had been collected online and purposively through Posyandu cadres who had access to family/community in October-December 2020. Data analysis used the chi-square test and multiple logistic …

Covid-19 Pandemic And Ghana’S Economy: A Deep Dive Into Economic Indicators, Williams Kwasi Peprah, Isaac Anowuo [email protected], Ebenezer Owusu-Yeboah, Daniel Adofo Kwakye Ameyaw, Lucile Sabas

Faculty Publications

The study presents an in-depth analysis of the COVID-19 pandemic’s effect on Ghana’s gross domestic product (GDP), balance of payments and international investment position (BPM6), and inflation (INFL). Employing a pre-and post-COVID-19 comparison (2017-2022) through repeated measures ANOVA and tests of between-subject effects, it investigates whether the government’s economic performance was significantly impacted. Key findings show a notable decrease in GDP and BPM6, alongside a major increase in inflation rates post-pandemic. The study concludes that the COVID-19 pandemic had a statistically significant impact on Ghana’s economic performance in terms of GDP and BPM6, but not inflation. Recommendations include implementing economic …

Evaluation And Lessons Learned From The Dissemination And Implementation Science Scholars Program In The National Cancer Prevention And Control Research Network, Daniela B. Friedman, Cam Escoffery, Elaine H. Morrato, Cynthia A. Thomson, Courtney N. Petagna, Freda Allyson Hucek, Mary Wangen, Aubrey Villalobos, James R. Hébert Scd, Samuel Noblet, Mayank Sakhuja, David O. Garcia, Jennifer L. Cruz, Stephanie B. Wheeler

Faculty Publications

Background:

The Centers for Disease Control and Prevention (CDC)-funded Cancer Prevention and Control Research Network (CPCRN) has been a leader in cancer-related dissemination & implementation (D&I) science. Given increased demand for D&I research, the CPCRN Scholars Program launched in 2021 to expand the number of practitioners, researchers, and trainees proficient in cancer D&I science methods. Methods:

The evaluation was informed by a logic model and data collected through electronic surveys. Through an application process (baseline survey), we assessed scholars’ competencies in D&I science domains/subdomains, collected demographic data, and asked scholars to share proposed project ideas. We distributed an exit survey …

Anesthesia For Bronchoscopy-An Update, Basavana Goudra, Lalitha Sundararaman, Prarthna Chandar, Michael Green

Department of Anesthesiology Faculty Papers

The field of interventional pulmonology has grown immensely and is increasingly recognized as a subspecialty. The new procedures introduced in the last decade pose unique challenges, and anesthesiologists need to readapt to their specific demands. In this review, we extensively discuss the pathophysiology, technical aspects, preprocedural preparation, anesthetic management, and postprocedural challenges of many new procedures such as navigational bronchoscopy, endobronchial valve deployment, and bronchial thermoplasty. Majority of these procedures are performed under general anesthesia with an endotracheal tube. Total intravenous anesthesia with rocuronium as a muscle relaxant seems to be the standard US practice. The easy availability and proven …

Assessing The Relative Efficacy Of Components Of Opioid-Free Anaesthesia In Adult Surgical Patients: Protocol For A Systematic Review And Component Network Meta-Analysis, Amparo Belltall, Guido Mazzinari, Aisling Ní Eochagáin, Tom Wall, Ary Serpa Neto, Oscar Diaz-Cambronero, Daniel Sessler, Donal J Buggy, Juan Cata, Markus W Hollmann

Faculty, Staff and Student Publications

Introduction: The rise of opioid-free anaesthesia (OFA) aims to reduce postoperative pain while reducing opioid-related side effects during surgery. However, the various adjuvant agents used in OFA complicate the evaluation of their effectiveness and risks. Recent reviews question the clinical benefits of OFA, highlighting the need for thorough evaluation. This protocol describes a network meta-analysis to compare the effectiveness of OFA with opioid-based anaesthesia and will identify key components for optimal postoperative outcomes.

Methods and analysis: We will perform a systematic search of literature published in English without time restriction in Embase, The Cochrane Library, MEDLINE (via PubMed) and CINAHL, …

Short-Term Outcomes Of A Healthy Relationship Intervention For The Prevention Of Sexual Harassment And Sexual Assault In The Us Military: Pilot Pretest-Postest Study, Belinda Hernandez, Ross Shegog, Christine Markham, Susan Emery, Elizabeth Baumler, Laura Thormaehlen, Rejane Andina Teixeira, Yanneth Rivera, Olive Pertuit, Chelsey Kanipe, Iraina Witherspoon, Janis Doss, Victor Jones, Melissa Peskin

Faculty, Staff and Student Publications

BACKGROUND: Sexual harassment (SH) and sexual assault (SA) are serious public health problems among US service members. Few SH and SA prevention interventions have been developed exclusively for the military. Code of Respect (X-CoRe) is an innovative web-based, multilevel, SA and SH intervention designed exclusively for the active-duty Air Force. The program's goal is to increase Airmen's knowledge and skills to build and maintain respectful relationships, ultimately reducing SH and SA and enhancing Airmen's overall well-being and mission readiness.

OBJECTIVE: This pilot study aimed to assess the short-term psychosocial impact (eg, knowledge, attitudes, and self-efficacy) of the web-based component of …

Chikungunya Pathogenesis In Cardiac Tissues And Its Evaluation In Stem Cell Derived Cardiac Models, Elizabeth M. Traverse

USF Tampa Graduate Theses and Dissertations

Chikungunya Virus (CHIKV) is a single stranded RNA alphavirus primarily vectored by Aedes aegypti and Aedes albopictus mosquitos. CHIKV has circulated in tropical and sub-tropical regions of Africa and Asia, but outbreaks in the past two decades have seen the virus spread to Europe, South America, and the Caribbean. Disease from CHIKV infection typically results in fever, malaise, and sometimes debilitating arthralgia. However, there are concerning abnormal presentations that affect the human heart, including myocarditis, heart failure, and death. These symptoms are seen in all age groups and sexes and are not connected to particular strains or mutations in the …