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Looking Back, Moving Forward: Implementing Pmtct Programs In Resource-Constrained Settings, Horizons Studies 1999 To 2007, Carolyn Baek, Naomi Rutenberg Jan 2010

Looking Back, Moving Forward: Implementing Pmtct Programs In Resource-Constrained Settings, Horizons Studies 1999 To 2007, Carolyn Baek, Naomi Rutenberg

HIV and AIDS

In 1997, the Population Council initiated the Horizons Program—a decade-long USAID-funded collaboration with the International Center for Research on Women, the International HIV/AIDS Alliance, PATH, Tulane University, Family Health International, and Johns Hopkins University—designing, implementing, evaluating, and expanding innovative strategies for HIV prevention and care. Horizons developed and tested ways to optimize HIV prevention, care, and treatment programs; worked to reduce stigma and improve gender-biased behaviors; and greatly expanded knowledge about the best ways to support, protect, and treat children affected by HIV and AIDS. In all its projects, Horizons strengthened the capacity of local institutions by providing support and …


Looking Back, Moving Forward: Improving The Lives Of Orphans And Other Children Affected By Aids, Horizons Studies 1998 To 2007, Katie D. Schenk, Annie P. Michaelis, Tobey C. Nelson, Lisanne Brown, Ellen Weiss Jan 2010

Looking Back, Moving Forward: Improving The Lives Of Orphans And Other Children Affected By Aids, Horizons Studies 1998 To 2007, Katie D. Schenk, Annie P. Michaelis, Tobey C. Nelson, Lisanne Brown, Ellen Weiss

HIV and AIDS

In 1997, the Population Council initiated the Horizons Program—a decade-long USAID-funded collaboration with the International Center for Research on Women, the International HIV/AIDS Alliance, PATH, Tulane University, Family Health International, and Johns Hopkins University—designing, implementing, evaluating, and expanding innovative strategies for HIV prevention and care. Horizons developed and tested ways to optimize HIV prevention, care, and treatment programs; worked to reduce stigma and improve gender-biased behaviors; and greatly expanded knowledge about the best ways to support, protect, and treat children affected by HIV and AIDS. In all its projects, Horizons strengthened the capacity of local institutions by providing support and …


Increasing The Use Of Booster Seats: A Community-Based Research Project, Michelle Gallina, Amanda Jones, Jane Kim, Habibullah Muhiddin, Natasha Singletary Jan 2010

Increasing The Use Of Booster Seats: A Community-Based Research Project, Michelle Gallina, Amanda Jones, Jane Kim, Habibullah Muhiddin, Natasha Singletary

OUR Journal: ODU Undergraduate Research Journal

The aim of this project was to increase booster seat usage and knowledge of booster seat safety by implementing population-based interventions in the community. To aid in accomplishing the goal, the nursing students utilized the performance of an educational puppet show, educational handouts, and aggregate height and age screening as the interventions. Pre and post tests data were obtained. As a result, there was an increase of the aggregates‟ desire to be in a booster seat. Nurses who take more action in a leadership role by implementing interventions based on the educational needs of the community increased booster seat awareness. …


Who Shares? Managerial Knowledge Transfer Practices In British Columbia's Ministry Of Health Services, Gwendolyn Elizabeth Lock Jan 2010

Who Shares? Managerial Knowledge Transfer Practices In British Columbia's Ministry Of Health Services, Gwendolyn Elizabeth Lock

Walden Dissertations and Doctoral Studies

The British Columbia government's Ministry of Health Services will experience significant loss of operational knowledge from an aging managerial workforce, increased staff turnover, and difficulties in recruitment. The purpose of this study is to provide the ministry's Strategic Human Resources Planning branch staff with a map and description of knowledge transfer practices used by approximately 40 managers within the ministry's Health Sector Information Management/Information Technology division and its Vital Statistics Agency. The study is a mixed-methods case study of knowledge retention and transfer practices founded on a knowledge management and social network theoretical foundation. To understand the ministry's complex nature …


Risk Factors For Development Of High Blood Pressure And Obesity Among African American Adolescents, Monique Shanta White Jan 2010

Risk Factors For Development Of High Blood Pressure And Obesity Among African American Adolescents, Monique Shanta White

Walden Dissertations and Doctoral Studies

Childhood obesity has reached epidemic proportions in the United States and has been linked to hypertension, especially among African American youth. Optimistic bias leads youth to underestimate their susceptibility to negative health outcomes. Public health officials want to reduce risk factors to result in significant long term reduction in cardiovascular disease. The purpose of this study was to explore adolescent behavior practices in a school district and prevalence of high blood pressure and obesity in that population. The health belief model guided the framework for this study. Research questions examined relationship between individual health risk practices and optimistic bias on …


The Relationship Between Leadership Styles And Performance Success In Hospitals, Beverly J. D. Hernandez Jan 2010

The Relationship Between Leadership Styles And Performance Success In Hospitals, Beverly J. D. Hernandez

Walden Dissertations and Doctoral Studies

Upheavals in the health care landscape threaten the sustainability of contemporary hospital organizations. Yet there is limited research regarding the characteristics of leaders within successful hospitals. The problem is the leadership styles needed to effectively run hospital organizations have not been identified and/or established. The purpose of this study was to develop a model of congruent leadership styles linked to the success of hospitals in one metropolitan city. The research questions sought to uncover (a) consistent leadership styles within successful hospitals, and (b) what, if any, relationship exists between leadership styles and measures of success. Examination of the literature uncovered …


From Infanticide To Activism: The Transformation Of Emotions And Identity In Self-Help Movements, Verta Taylor, Lisa A. Leitz Jan 2010

From Infanticide To Activism: The Transformation Of Emotions And Identity In Self-Help Movements, Verta Taylor, Lisa A. Leitz

Peace Studies Faculty Books and Book Chapters

Taylor and Leitz trace processes of collective identity construction and politicization among women suffering from postpartum psychiatric illness who have been convicted of infanticide. Joining a growing body of research suggesting that self‐help and consumer health movements can be a significant force for change in both the cultural and political arenas, Taylor and Lietz examine one such movement, a pen‐pal network of women incarcerated for committing infanticide. Taylor and Leitz show how a sense of collective identity fostered by the pen‐pal network triggered a profound emotional transformation in participants, allowing them to convert shame and loneliness into pride and solidarity, …


A Policy And Intervention For Overweight Children And Adolescents, Kimberly K. Mcclanahan, Marlene B. Huff, Hatim A. Omar Jan 2010

A Policy And Intervention For Overweight Children And Adolescents, Kimberly K. Mcclanahan, Marlene B. Huff, Hatim A. Omar

Pediatrics Faculty Publications

The global epidemic of childhood and adolescent overweight has become a major public health concern. Not only are these youth more likely to become obese adults, and thus more prone to obesity-related diseases than their non overweight peers, they are also likely to suffer emotional and social effects associated with overweight. Overweight in youth has been linked to depression, low self-esteem, eating disorders, negative body image, and stigma. It appears to be bi-directional in nature, with overweight sometimes predicting certain psychological effects and psychosocial issues sometimes predicting overweight. Effective assessment and treatment of psychological and mental health issues in overweight …


Childhood Home Injuries: A Nursing Student Approach To Preventing Childhood Home Injuries, Jinging Sparrow, Katherine Carman, Katelyn Kerr, Renee Farmer Jan 2010

Childhood Home Injuries: A Nursing Student Approach To Preventing Childhood Home Injuries, Jinging Sparrow, Katherine Carman, Katelyn Kerr, Renee Farmer

OUR Journal: ODU Undergraduate Research Journal

Unintentional injuries are the leading cause of death for children under 14 years of age. Of the unintentional injuries, a significant portion occurs within the home setting. Creating a safe home environment for children has become a focus in current efforts for health promotion and injury prevention. Our objective is to enhance caregivers’ knowledge of home safety thus decreasing the incidence of childhood unintentional injuries. To this end, a series of educational workshops were conducted on poisoning, choking, furniture tip-over, scalds and burns. The material was presented via PowerPoint, videos, posters, handouts, demonstrations and return demonstrations. Verbal pre-and post tests …


Effect Of Dai Training On Maternal And Neonatal Care: An Operations Research Study, Peter C. Miller, Gul Rashida, Abdul Wajid, Zeba Tasneem, Lubna Mahmood, Minhaj Ul Haque Jan 2010

Effect Of Dai Training On Maternal And Neonatal Care: An Operations Research Study, Peter C. Miller, Gul Rashida, Abdul Wajid, Zeba Tasneem, Lubna Mahmood, Minhaj Ul Haque

Reproductive Health

This study examines the use of training traditional birth attendants, or "dais" as they are known in Pakistan, to reduce maternal mortality. By training dais to adopt safer routine delivery, newborn care practices, and recognize and refer in case of emergencies, dais can improve maternal and neonatal health. While one group of women met with specially trained dais who received Safe Motherhood Applied Research Training (SMART), a control group met with dais who offered health services only. The objectives of this evaluation were to determine whether dais substantially improved their performance after attending the "SMART dai" training course, to determine …


Increasing Complete Immunization In Rural Uttar Pradesh: Implications For Behavior Change Communication, Population Council Jan 2010

Increasing Complete Immunization In Rural Uttar Pradesh: Implications For Behavior Change Communication, Population Council

Reproductive Health

The Population Council conducted a formative study in rural Uttar Pradesh, India to determine the current rate of compliance for recommended schedules of child immunization, identify the barriers and factors facilitating the uptake of full immunization, and identify behavior change communication (BCC) initiatives that could accelerate adoption of this practice. This policy brief identifies a number of barriers to immunization: low risk perception, lack of faith in vaccines, lack of knowledge about vaccines, fear of side effects, lack of family support, and lack of knowledge about location and type of services available. The brief also identifies several facilitating factors and …


Increasing Institutional Delivery And Access To Emergency Obstetric Care Services In Rural Uttar Pradesh: Implications For Behavior Change Communication, Population Council Jan 2010

Increasing Institutional Delivery And Access To Emergency Obstetric Care Services In Rural Uttar Pradesh: Implications For Behavior Change Communication, Population Council

Reproductive Health

The Population Council conducted a formative in rural Uttar Pradesh (UP), India to determine the impact of the Janani Suraksha Yojana (JSY) scheme on the current status of institutional delivery in the region, to understand the facilitating factors and barriers in delivering in a health facility, and to identify programmatic and behavior change communication (BCC) initiatives that could accelerate the adoption of institutional delivery. JSY was launched as an intervention to address the barriers to institutional delivery, through the introduction of community-based women volunteers. The study shows that with the introduction of the JSY the rate of institutional delivery jumped …


Referral Mechanism Improves Uptake Of Art Services For Hiv+ Fp Clients, Population Council Jan 2010

Referral Mechanism Improves Uptake Of Art Services For Hiv+ Fp Clients, Population Council

Reproductive Health

An operations research intervention by the Population Council in Kenya aimed to design a referral framework for linking HIV‐positive family planning (FP) clients to treatment and care in selected health facilities. The project also assessed the acceptability and effectiveness in increasing the number of eligible HIV‐positive FP clients receiving HIV care and treatment services. This summary details the effort to improve the linkage between FP services and comprehensive care centers that led to a dramatic increase in the proportions of HIV-positive clients in FP clinics who go on to receive HIV/AIDS treatment and care services at the same facility. Recommendations …


Maternal And Neonatal Health Services In Sudan: Results Of A Situation Analysis, Nahla G. Abdel-Tawab, Maha El-Rabbat Jan 2010

Maternal And Neonatal Health Services In Sudan: Results Of A Situation Analysis, Nahla G. Abdel-Tawab, Maha El-Rabbat

Reproductive Health

This project brief is based on the results of a situation analysis (SA) study that was done collaboratively by the Population Council and Sudan Ministry of Health (MOH) with funds from UNFPA, UNICEF, and Packard Foundation. The analysis showed an uneven distribution of reproductive health (RH) staff across Sudan, and nurses and nurse midwives are the key in RH services. There was also limited access to family planning services. Antenatal care was limited, and pregnant women in the study seldom received counseling on birth spacing or birth preparedness. Birth attendants also lacked adequate knowledge and skills. Emergency obstetric care was …


Mental Health And Substance Abuse Issues Among Native Americans Living On A Remote Reservation: Results From A Community Survey, Theodore W. Mcdonald, Mary E. Pritchard Jan 2010

Mental Health And Substance Abuse Issues Among Native Americans Living On A Remote Reservation: Results From A Community Survey, Theodore W. Mcdonald, Mary E. Pritchard

Public and Population Health Faculty Publications and Presentations

The purpose of the study was to document the perceived and actual mental health and substance abuse issues of residents living on a remote reservation in the Northwestern United States. Surveys were completed by 138 Native Americans, who reported on mental health status and problems, perceptions of personal and community health issues on the reservation, and patterns of substance use and abuse (e.g., how often respondents use alcohol, what drugs present the most serious problems on the reservation). The respondents perceived their own mental health to be quite good. However, they reported that several mental health problems were prevalent in …


Rural Idaho Family Physicians’ Scope Of Practice, Ed Baker, David Schmitz, Ted Epperly, Ayaka Nukui, Carissa Moffat Miller Jan 2010

Rural Idaho Family Physicians’ Scope Of Practice, Ed Baker, David Schmitz, Ted Epperly, Ayaka Nukui, Carissa Moffat Miller

Public and Population Health Faculty Publications and Presentations

Context: Scope of practice is an important factor in both training and recruiting rural family physicians.

Purpose: To assess rural Idaho family physicians’ scope of practice and to examine variations in scope of practice across variables such as gender, age and employment status.

Methods: A survey instrument was developed based on a literature review and was validated by physician educators, practicing family physicians and executives at the state hospital association. This survey was mailed to rural family physicians practicing in Idaho counties with populations of less than 50,000. Descriptive, bivariate and multivariate analyses were employed to describe and compare scope …


Hospital Evacuations: Historical Precedence And Modern Preparedness, Nicholas Squillace Jan 2010

Hospital Evacuations: Historical Precedence And Modern Preparedness, Nicholas Squillace

Master of Public Health Program Student Publications

Objectives: The purpose of this research was to identify common problems encountered during hospital evacuations and how those problems are or should be addressed when creating a hospital evacuation plan.

Methods: Articles relating to hospital evacuations were retrieved from PubMed and CINAHL in addition to government websites and the Joint Commission on Accreditation of Healthcare Organizations. The articles collected were limited to within the last 20 years, from 1990 to 2010. Hospital plans were collected from search engines including Google and Yahoo. Moreover, a plan was obtained from a Dayton area hospital.

Results: Numerous instances of hospital evacuations that were …


The Relationship Between Body Image And Body Mass Index In Attendees At A Health Fair, Millie S. Olds Jan 2010

The Relationship Between Body Image And Body Mass Index In Attendees At A Health Fair, Millie S. Olds

Master of Public Health Program Student Publications

The purpose of this study was to examine the relationship between body image and body mass index (BMI) in attendees at a health fair. BMI and body image was also compared between races, ages and genders. It was hypothesized that there would be discrepancies between perceived body image and weight status, as measured by BMI. Sixty-two participants at a health fair in Cincinnati completed a survey about perceived body image and had their height and weight measured and BMI calculated later. Results suggested a positive relationship between BMI and body image. Participants with a higher BMI identified themselves with a …


Unmet Medical Need Of Underserved Population In A Safety-Net Organization, Leslie Clem Jan 2010

Unmet Medical Need Of Underserved Population In A Safety-Net Organization, Leslie Clem

Master of Public Health Program Student Publications

Background: Safety net providers serve a large proportion of America’s uninsured and low income population. The purpose of this study is to determine if differences in unmet medical needs exist between the provisional and clinic populations, age groups, and sex and race categories. This research study provides information about the population that receives services from Good Neighbor House, a non-profit social service organization in Dayton, Ohio.

Methods: GNH created a survey to assess the unmet medical need of their clients. The instrument contains questions about routine medical care, unmet medical care in the last 12 months, medical bills, and demographic …


A Benefits-Based Study Of Appalachian Trail Users: Validation And Application Of The Benefits Of Hiking Scale, Barbara Freidt, Eddie Hill, Edwin Gomez, Marni Goldenberg Jan 2010

A Benefits-Based Study Of Appalachian Trail Users: Validation And Application Of The Benefits Of Hiking Scale, Barbara Freidt, Eddie Hill, Edwin Gomez, Marni Goldenberg

Human Movement Studies & Special Education Faculty Publications

Lack of exercise has been linked to poor health issues (e.g., obesity) in American society. National (e.g., Appalachian Trail) and local trails are a potential resource for championing physical activity. To challenge sedentary lifestyle choices and promote more active ones, an understanding of the benefits perceived to be associated with physical and outdoor activities is needed. A total of 454 Appalachian Trail user surveys were collected. Validity analyses and reliability analyses showed the Benefits of Hiking Scale to be an accurate and consistent measure of the dimensions of recreation benefits. Within the improved condition dimension of Benefits, significant differences were …


Factors Affecting Enrolment Of Plhiv Into Art Services In India, Avina Sarna, Damodar Bachani, Mary Philip Sebastian, Ruchi Sogarwal, Madhusudana Battala Jan 2010

Factors Affecting Enrolment Of Plhiv Into Art Services In India, Avina Sarna, Damodar Bachani, Mary Philip Sebastian, Ruchi Sogarwal, Madhusudana Battala

HIV and AIDS

At the end of 2007, India had an estimated 2.31 million people living with HIV, and an HIV prevalence of 0.34 percent. Despite the low HIV prevalence, these statistics place India among countries with a large number of people living with HIV (PLHIV). To address the care and support needs of PLHIV, the Ministry of Health and Family Welfare, Government of India, initiated a national program in 2004 to provide free antiretroviral therapy (ART) for PLHIV. By March 2009, there were 211 functioning Antiretroviral Treatment Centers and 254 Community Care Centers across the country, and to date 217,781 individuals are …


The Healthy Food Slide Rule (Hfsr): A Nutrition Education Tool For Children, Elaine M. Long, Uwe Reischl, Barbara B. Abo Jan 2010

The Healthy Food Slide Rule (Hfsr): A Nutrition Education Tool For Children, Elaine M. Long, Uwe Reischl, Barbara B. Abo

Public and Population Health Faculty Publications and Presentations

The Healthy Food Slide Rule (HFSR) is a new educational tool designed specifically for use by school children in grades 4-6. The HFSR teaches the importance of including the 5 food groups and the importance of complying with appropriate portion sizes as presented in MyPyramid.1, 2 The portion size information included in the HFSR combines the healthy eating and physical activity messages offered by MyPyramid for Kids.3, 4 The new tool can be easily incorporated into existing math lessons (weights, measures, and fractions), into language arts lessons, or into science lessons.5


Introducing A Multi-Site Program For Early Diagnosis Of Hiv Infection Among Hiv-Exposed Infants In Tanzania, Harriet Nuwagaba-Biribonwoha, Bazghina Werq-Semo, Aziz Abdallah, Amy Cunningham, John G. Gamaliel, Sevestine Mtunga, Victoria Nankabirwa, Isaya Malisa, Luis F. Gonzalez, Charles Massambu, Denis Nash, Jessica Justman, Elaine J. Abrams Jan 2010

Introducing A Multi-Site Program For Early Diagnosis Of Hiv Infection Among Hiv-Exposed Infants In Tanzania, Harriet Nuwagaba-Biribonwoha, Bazghina Werq-Semo, Aziz Abdallah, Amy Cunningham, John G. Gamaliel, Sevestine Mtunga, Victoria Nankabirwa, Isaya Malisa, Luis F. Gonzalez, Charles Massambu, Denis Nash, Jessica Justman, Elaine J. Abrams

Publications and Research

Background: In Tanzania, less than a third of HIV infected children estimated to be in need of antiretroviral therapy (ART) are receiving it. In this setting where other infections and malnutrition mimic signs and symptoms of AIDS, early diagnosis of HIV among HIV-exposed infants without specialized virologic testing can be a complex process. We aimed to introduce an Early Infant Diagnosis (EID) pilot program using HIV DNA Polymerase Chain Reaction (PCR) testing with the intent of making EID nationally available based on lessons learned in the first 6 months of implementation.

Methods: In September 2006, a molecular biology laboratory at …


Epigenetics: Blurring The Line Between Nature And Nurture, Elizabeth H. Rose Jan 2010

Epigenetics: Blurring The Line Between Nature And Nurture, Elizabeth H. Rose

CMC Senior Theses

This long-standing nature versus nurture debate is cited in behavioral and physical expressions of disease dysfunctions, resiliencies, and recovery. Their purposes are noted both in scientific pursuits as well as literature. This discourse has been particularly intense in the fields of psychology, psychiatry, and biology where there is a long history of scientists’ attempts to disprove or discredit others’ intellectual and professional measures. Interestingly, recent advances in the neurosciences and genetic technologies have brought these fields closer together with a new focus – the interactional relationship between nature and nurture – epigenetics.


Monitoring And Evaluation Of The Emergency Plan Progress (Meepp): End-Of-Project Evaluation, Sam Kalibala Jan 2010

Monitoring And Evaluation Of The Emergency Plan Progress (Meepp): End-Of-Project Evaluation, Sam Kalibala

HIV and AIDS

This report evaluates the scope of the Monitoring and Evaluation of the Emergency Plan Progress (MEEPP) and the lessons learned from the project in Uganda, which aims to improve availability and quality of PEPFAR data.


A Single Case Study Of A Three Year Coordinated School Health Program At A Rural North Mississippi Elementary School, Sandra Lena Howell Jan 2010

A Single Case Study Of A Three Year Coordinated School Health Program At A Rural North Mississippi Elementary School, Sandra Lena Howell

Electronic Theses and Dissertations

The single case study presents the story of the implementation of a three year Coordinated School Health Program (CSHP) at a rural North Mississippi school. The school was recognized by the Mississippi Department of Education, Office of Healthy Schools, as one of ten selected model Mississippi healthy schools. An awarded grant of one hundred thousand dollars funded the implementation of the CSHP over a three year period. The study examined the impact of the CSHP on the students, staff, and personnel. Two types of data were collected and analyzed including archived documents and interviews conducted with five members of the …


Bioethics And Biosecurity Education In China: Rise Of A Scientific Superpower., Barr S. Michael, Joy Yueyue Zhang Jan 2010

Bioethics And Biosecurity Education In China: Rise Of A Scientific Superpower., Barr S. Michael, Joy Yueyue Zhang

Book Chapters

This chapter explores ethics, education and the life sciences in China. It is based on work conducted by the authors in two separate but complimentary projects. Barr’s observations derive from interviews and discussions in Beijing, Shanghai and Guangzhou with life scientists and policymakers in infectious-disease hospitals, university-research labs, the Chinese Academy of Sciences, and the Ministry of Health. Zhang’s study focused on China’s governance of stem-cell research and involved interviews with scientists, ethicists and policymakers at more than 25 sites across China. Below, we set the context by describing the role of science in China’s quest to become a leading …


Resting Energy Expenditure Changes With Weight Loss: Racial Differences, Xuewen Wang, Tongjian You, Leon Lenchik, Barbara J. Nicklas Jan 2010

Resting Energy Expenditure Changes With Weight Loss: Racial Differences, Xuewen Wang, Tongjian You, Leon Lenchik, Barbara J. Nicklas

Faculty Publications

It is controversial whether weight loss reduces resting energy expenditure (REE) to a different magnitude in black and white women. This study was to determine whether changes in REE with weight loss were different between black and white postmenopausal women, and whether changes in body composition (including regional lean and fat mass) were associated with REE changes within each race. Black (n= 26) and white (n= 65) women (age= 58.2±5.4 years, 25< BMI< 40 kg·m−2) completed a 20-week weight loss intervention. Body weight, lean and fat mass (total body, limb and trunk) via dual energy X-ray absorptiometry, and REE via indirect …


Racial Disparities Between The Sex Steroid Milieu And The Metabolic Risk Profile, Arlette C. Perry, Xuewen Wang, Ronald B. Goldberg, Robert Ross, Loreto Jackson Jan 2010

Racial Disparities Between The Sex Steroid Milieu And The Metabolic Risk Profile, Arlette C. Perry, Xuewen Wang, Ronald B. Goldberg, Robert Ross, Loreto Jackson

Faculty Publications

Aims and Method. The present study examined the relationship between the metabolic risk profile (MRP) and total testosterone (TT) and free testosterone using the free androgen index (FAI) and sex hormone binding globulin (SHBG) in 36 Caucasian American (CA) and 30 African-American (AA) women volunteering for a weight loss study. Results. After controlling for age, significant relationships were found between TT and diastolic blood pressure (P = .004 and P = .015 in CA and AA women, resp.). Additionally, total cholesterol (P = .003), low density lipoprotein cholesterol (P = .004), apolipoprotein B (P = .006), …


Metabolic Actions Of Insulin In Men And Women, Faidon Magkos, Xuewen Wang, Bettina Mittendorfer Jan 2010

Metabolic Actions Of Insulin In Men And Women, Faidon Magkos, Xuewen Wang, Bettina Mittendorfer

Faculty Publications

Insulin is an important regulator of glucose, lipid and protein metabolism. It suppresses hepatic glucose and triglyceride production, inhibits adipose tissue lipolysis and whole-body and muscle proteolysis and stimulates glucose uptake in muscle. In this review we discuss what is currently known about the control of substrate metabolism by insulin in men and women. The data available so far indicate that women are more sensitive to insulin with regards to glucose metabolism (both in the liver and in muscle) whereas there are no differences between men and women in insulin action on lipolysis. Potential differences exist in the regulation of …