Digital Commons Network^™

Global Response To Local Problems:The Global Health Community Response To The Ebola Outbreak Of 2014, Nicole Thelen

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Health crises are often met with much support from the global health aid communities, who strive to contain the current health crisis and improve the conditions of the affected society. The recent Ebola outbreak of 2014 is no exception. Driven by public panic and media coverage, the global health community responded in force, dispatching aid organizations, monetary help, and military assistance to both assist those affected with the disease and prevent it from spreading. The World Health Organization, along with Doctors without Borders and many other global organizations, swept in to provide aid to the affected areas. This project examines …

Low Level Lead Exposure And Inflammatory Markers In The Brains Of C57bl/6j Mice, Miguel A. Cervantes

Open Access Theses & Dissertations

Background and Significance: Prior studies have indicated that early chronic low-level lead exposure may be associated with adverse effects on motor and cognitive functions. The mechanisms by which low-level lead affects brain function are unknown. Objectives: The current study aimed to (1) determine whether early chronic low-level lead exposure altered the expression of pro- or ant-inflammatory cytokines and markers of oxidative stress in mouse brain studied at two ages, pre-adolescence (PND 28) and early adulthood (PND 40); and (2) in the same pre-adolescent and early adulthood mice, compare and contrast the levels of pro- or ant-inflammatory markers in three brain …

Mental Health Professionals' Attitude And Perception Of Their Role In Tackling Substance Abuse And Related Disorders In Nigeria, Olubusayo Ruth Akinola

Walden Dissertations and Doctoral Studies

Mental health professionals (MHPs) play a pivotal role in enhancing treatment outcomes for drug-using populations and minimizing their harm to the public. In response to a gap in the literature, this study sought to (a) assess MHPs' attitudes about the use and abuse of substances and their perception of their role in tackling substance abuse and related disorders in Nigeria, (b) identify predictors of perception, and (c) explore regional variations in attitude. Based on the validated drug and drug users' problems perception questionnaire and the substance abuse attitude survey, a cross-sectional survey was conducted in a randomized sample of 292 …

Patient And Provider Characteristics And Practice Patterns Of Primary Care Physicians Of Weight-Related Counseling, Kolby T. Redd

Theses and Dissertations

Background: The United States Preventive Services Task Force (USPSTF) recommends three types of health education counseling for use in primary care practices for adult, obese patients. While these recommendations are well known, a low percentage of physicians provide this counseling to their patients on a consistent basis. There are inconsistencies in past studies in regards to what aspects of the health encounter influence the likelihood of receiving health education counseling during a primary care visit. The objective of this study was to (1) investigate the patterns of these three types of counseling occurring within primary care practices and to …

Dancing Around Infertility: The Use Of Metaphors In A Complex Medical Situation, Angela L. Palmer-Wackerly, Janice L. Krieger

Department of Communication Studies: Faculty Publications

People use metaphors to cognitively frame their experiences as well as to explain those experiences to others, especially in complex medical situations. However, previous research has not fully explored the extent to which metaphors may be helpful or harmful to achieving well-being. This investigation fills this gap by identifying and explaining metaphor use in the context of infertility. Guided by self-determination theory, in-depth interviews were conducted with 22 women and men who had experienced an inability to conceive a child. Analysis of participant narratives yielded 10 prominent metaphors that reflect how participants’ need for competence, autonomy, and relatedness were (and …

Evolution In Action: Climate Change, Biodiversity Dynamics And Emerging Infectious Disease, Eric P. Hoberg, Daniel R. Brooks

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Climatological variation and ecological perturbation have been pervasive drivers of faunal assembly, structure and diversification for parasites and pathogens through recurrent events of geographical and host colonization at varying spatial and temporal scales of Earth history. Episodic shifts in climate and environmental settings, in conjunction with ecological mechanisms and host switching, are often critical determinants of parasite diversification, a view counter to more than a century of coevolutionary thinking about the nature of complex host–parasite assemblages. Parasites are resource specialists with restricted host ranges, yet shifts onto relatively unrelated hosts are common during phylogenetic diversification of parasite lineages and directly …

Parasitology In An Archaeological Context: Analysis Of Medieval Burials In Nivelles, Belgium, S. E. Rácz, Elisa Pucu De Araujo, E. Jensen, C. Mostek, Johnica J. Morrow, M. L. Van Hove, R. Bianucci, D. Willems, F. Heller, Adauto Araujo, Karl Reinhard

Karl Reinhard Publications

Coprolites were recovered from three burials near the Grand Place of Nivelles, Belgium. These remains yielded evidence of geohelminth parasitism. The evidence contributes to studies of differential parasite egg preservation related to the taphonomic conditions within the three burials. Using coprolite analysis techniques, parasite egg concentrations were quantified for each burial. Coprolites from the individual in Burial 122 were abnormally large and abundant, indicating an intestinal blockage. Additionally, this individual hosted an extremely high number of parasites evinced by the calculated parasite egg concentrations (Trichuris trichiura = 1,577,679 total eggs; Ascaris lumbricoides = 202,350 total eggs). Statistical analyses revealed …

Paleoparasitology – Human Parasites In Ancient Material, Adauto Araújo, Karl Reinhard, Luiz Fernando Ferreira

Karl Reinhard Publications

Parasite finds in ancient material launched a new field of science: paleoparasitology. Ever since the pioneering studies, parasites were identified in archaeological and paleontological remains, some preserved for millions of years by fossilization. However, the paleoparasitological record consists mainly of parasites found specifically in human archaeological material, preserved in ancient occupation sites, from prehistory until closer to 2015. The results include some helminth intestinal parasites still commonly found in 2015, such as Ascaris lumbricoides, Trichuris trichiura and hookworms, besides others such as Amoebidae and Giardia intestinalis, as well as viruses, bacteria, fungi and arthropods. These parasites as a …

Forensic Palynological Analysis Of Intestinal Contents Of A Korean Mummy, Paulette Arguelles, Karl Reinhard, Dong Hoon Shin

Karl Reinhard Publications

Experimental studies show that pollen resides in the intestinal tract for a minimum of seven days to at least 21 days. Because of this long residence time, pollen analysis is an important avenue of forensic research. Pollen provides evidence of the environment of the decedent as well as foods and medicine. We analyzed a coprolite recovered from a Korean mummy. The decedent was a high-ranking general who lived during the 16th or 17th centuries. Twenty pollen types were recovered. These ranged from 100s to 10,000s of pollen grains per gram of coprolite. Importantly, comparison of the coprolite pollen spectrum to …

‘‘We Can Wipe An Entire Culture’’: Fears And Promises Of Dna Biobanking Among Native Americans, Roberto Abadie, Kathleen Heaney

Department of Sociology: Faculty Publications

This paper explores Native American perceptions on DNA biobanking. A qualitative study was conducted among self-declared Native Americans living off reservation in two Midwest cities. Findings demonstrate a paradox: Informants maintain strong hopes for the transformative power of gene-based research while voicing very particular social anxieties. Emerging genomic technologies elicit concerns over the potential for genetic stigmatization or discrimination based on race, preventing access to health insurance or employment. Frequently, social anxieties adopt the narrative form of conspiracy theories which portray powerful agents exploiting or abusing a disenfranchised population. We argue that while Native Americans do not have a monopoly …

Exploring The Risk Factors That Influence The Parental Dental Deferment Decision, Megan White

Walden Dissertations and Doctoral Studies

When caregivers defer their personal routine dental care (RDC) in order to provide RDC for their children, they risk detrimental consequences in their personal health and the health of their children. The purpose of this qualitative case study was to identify the risk factors that led to the parental dental deferment decision. The oral health and personal care services conceptual models guided the development of the research questions, facilitated the selection of risk factors on the decision-making process, and provided the basis for the data analysis thematic categories. Ten caregivers who made the decision to defer their personal RDC for …

Uric Acid Level Is Associated With Postprandial Lipemic Response To A High Saturated Fat Meal, Roy Gail Cutler

Walden Dissertations and Doctoral Studies

Hyperlipidemia caused by a diet high in saturated fat can lead to visceral fat weight gain, obesity, and metabolic syndrome. Being over-weight from visceral fat has been linked to increased risk of developing most age-related diseases and disability, along with a lower income potential and quality of life. However, researchers are just beginning to understand the biological mechanisms that regulate the conversion of excess calories into visceral fat storage rather than glycogen or muscle. Epidemiological studies have repeatedly shown a comorbid association between age-related diseases involving hyperlipemia and circulating levels of uric acid, but not a direct association. This study …

The Healthy, Hunger-Free Kids Act And High School Obesity, Derek Grills

Walden Dissertations and Doctoral Studies

United States high school student obesity rates have doubled in the past 30 years to 13%, threatening the health of millions of adolescents. To mitigate the epidemic, Congress passed the Healthy, Hunger-Free Kids Act (HHFKA) in 2010, which mandated significant changes to school nutrition and physical education. From a public policy perspective, the HHFKA changed school nutrition and exercise policy to affect obesity rates by changing intake and energy expenditure at school, though no study using national-level data examined this relationship. As such, the purpose of the study was to examine whether HHFKA policy compliance had a statistically significant effect …

An Assessment Of Sexually Transmitted Disease Knowledge Among 7th Grade Students, Racquel D. Weaver

Walden Dissertations and Doctoral Studies

Sexually transmitted diseases (STDs) continue to remain a public health concern in the United States, especially among young people. Levels of knowledge with regard to STDs have been investigated in prior research; however, these investigations have been limited primarily to older adolescents and young adults. Grounded in the social cognitive and subjective culture theories, this quantitative, cross-sectional study assessed STD knowledge (other than HIV/AIDS) among 7th grade students attending a public middle school in the United States. Demographic differences (age, gender, and ethnicity) in STD knowledge were examined to determine if these demographic variables predict STD knowledge scores and if …

Female Parents' Attitudes, Beliefs, And Perceptions About Youth Gun Crimes, Karen Annmaurisa Sylva-Givens

Walden Dissertations and Doctoral Studies

Youth gun crime is an important public health issue that affects many communities in the United States. Since 2012, there were over 30,000 gun-related deaths in the United States. Gun violence remains the leading cause of death for young people ages 15-24. This phenomenological study examined single female parents' attitudes, beliefs, and perceptions of the influences and causes of youth gun crimes. The purposive sample drew from 10 single female parents of youth ages 14-17 charged with gun crimes. Sutherlands' (1974) differential association theory provided the theoretical framework for the study. The mothers participated in a series of in-depth, face-to-face …

Racial Differences In The Impact Of A Worksite Wellness Program On Cardiovascular Biomarkers, Ceabert Joseph Griffith

Walden Dissertations and Doctoral Studies

Cardiovascular disease (CVD) is responsible for approximately 600,000 deaths in the United States each year, with African Americans (AAs) disproportionately affected. Individual-level approaches to reducing CVD remain ineffective, mobilizing a movement that advocates for population-based solutions. Workplace wellness programs (WWPs) have gained considerable traction as a viable strategy for ameliorating CVD burden among workers in general. However, no studies have looked at the efficacy of WWPs in ameliorating CVD specifically among AA employees--a knowledge gap that this investigation aimed to close. Based on the health belief model and the social cognitive theory, this retrospective cohort study used de-identified secondary data …

Educational Intervention: Effects On Heart Disease Risk Factor Knowledge Among African Americans, Linda M. Smith

Walden Dissertations and Doctoral Studies

Abstract

Fatal coronary heart disease among African Americans is associated with a

disproportionate burden of cardiovascular disease (CVD) risk factors. Research has indicated that CVD risk factor knowledge and the prevalence of ideal CVH both persist at suboptimal levels. However, few researchers have investigated the relationship between culturally-tailored community-based heart health sessions, short-term knowledge acquisition of CVD risk factors, and the awareness of the American Heart Association's (AHA's) CVH construct. The purpose of this cross-sectional, secondary analysis study was to examine the interplay between these variables in an urban African American sample. Guided by social cognitive theory, the study analyzed …

Survival Analysis Of Total Therapy 3 In Newly Diagnosed Multiple Myeloma, Scott Edward Bowman Miller

Walden Dissertations and Doctoral Studies

Multiple Myeloma (MM) is a hematologic malignancy that accounts for approximately 1% of all adult cancers. This study investigated the impact of patient distance traveled to MM care sites, which was not considered in previous research on any disease-specific staging or prognostic schema despite evidence suggesting that distance impacts patient outcome. This study investigated the impact of patient distance from the site of care on survival outcomes using a group of 480 clinical trial participants. Andersen's behavioral model of health services use functioned as the theoretical model for this study. The independent variable was patient travel distance, controlling for established …

Effect Of Placard Grading On Food Safety In Retail Food Facilities, Christopher Ogbonna Ogbu

Walden Dissertations and Doctoral Studies

Most people have had an episode of foodborne illness at one time or another; however, the majority of those stricken with foodborne illness fails to associate ill health with something consumed within the past 72 hours. The World Health Organization (WHO) estimates that foodborne diseases affect 30% of the population in developed countries, and that in developing countries, about 2 million people die yearly due to foodborne illness. Previous researchers have indicated that food handlers with poor personal hygiene are potential sources of infection. Although public health agencies in many countries already regularly inspect food facilities to control potential foodborne …

Stories Of Challenge And Resilience: The Impact Of Ecological Factors On The Lived Experiences Of Low Income, Urban Young Adults Living With Hiv/Aids, Kathleen Anne Thoma

UNF Graduate Theses and Dissertations

Transitioning to adulthood is a challenging experience for all young adults, but especially for those who are living with HIV/AIDS and residing in low income, urban areas. Young adults, particularly those who live in low income, urban areas, have the highest rate of new HIV cases among all age groups in the United States. The purpose of this study was to examine the lived experiences of a purposive sample of young adults living with HIV/AIDS who resided in a selected low income, urban area in order to better understand how ecological and health factors presented opportunities and challenges for resilience …

Cip10 Optimization For 4,4-Methylene Diphenyl Diisocyanate Aerosol Sampling And Field Comparison With Impinger Method, Silvia Puscasu, Simon Aubin, Yves Cloutier, Philippe Sarazin, Huu Van Tra, Sébastien Gagné

Études primaires

4,4-methylene diphenyl diisocyanate (MDI) aerosol exposure evaluation in spray foam insulation application is known as being a challenge because the spray foam application actually involves a fast-curing process. Available techniques are either not user-friendly or are inaccurate or not validated for this application. To address these issues, a new approach using a CIP10M was developed to appropriately collect MDI aerosol in spray foam insulation while being suitable for personal sampling. The CIP10M is a commercially available personal aerosol sampler that has been validated for the collection of microbial spores into a liquid medium. Tributylphosphate with 1-(2-methoxyphenyl)piperazine (MOPIP) was introduced into …

Individual, Family, And Social Factors Associated With Adolescent Obesity: A Policy Relevant Focus, Janice Marguerite Utley

All ETDs from UAB

INDIVIDUAL, FAMILY, AND SOCIAL FACTORS ASSOCIATED WITH ADOLESCENT OBESITY: A POLICY RELEVANT FOCUS JANICE M. UTLEY PUBLIC HEALTH ABSTRACT This dissertation is comprised of three papers that examined individual, family, and social factors associated with adolescent overweight and obesity with the aim of generating data that could inform the design of policy interventions to prevent or reverse rising prevalence. The first investigation was a type of literature review called a scoping study that examined the extent, range, and type of research activity on adolescent obesity that used a multilevel or hierarchical design to look at two or more contextual areas …

Statistical Methodology To Improve The Understanding Of Dna Methylation Data, Lindsay Leigh Waite Jones

All ETDs from UAB

The study of epigenetics involves the investigation of genomic elements that do not directly affect DNA sequence but are stable and preserved during cell division. One of the most commonly studied epigenetic elements is DNA methylation, which occurs when a methyl group is added to a cytosine residue in the DNA sequence. The advancement of technology to quantify DNA methylation, including bisulfite sequencing and bisulfite microarrays, has led to a large amount of available data. However, many questions still remain as to how to statistically analyze this data. This dissertation addresses some statistical concerns related to the analysis of DNA …

Presence And Mobilization Of Staphylococcus Aureus Pathogenicity Islands (Sapis) Among Bovine Mastitis Isolates, Laura Kate Parker

All ETDs from UAB

Bovine mastitis is inflammation of the mammary gland that occurs in cattle, as a result of invading bacteria. Staphylococcus aureus, a causative agent of bovine mastitis, produces toxins such as the toxic shock syndrome toxin (TSST-1) and the staphylococcal enterotoxins (SEs). The genes for these toxins are coded on S. aureus pathogenicity islands (SaPIs), which are mobile genetic elements associated with virulence factors. SaPIs can be mobilized by bacteriophages, resulting in the production of transducing particles that can spread virulence factors throughout a bacterial population. This research assessed the role and prevalence of SaPIs among bovine mastitis samples. In this …

The Normative Authority Of The World Health Organization, Lawrence O. Gostin, Devi Sridhar, Daniel Hougendobler

Georgetown Law Faculty Publications and Other Works

The World Health Organization (WHO) was born after the devastation of World War II, as a normative agency endowed with unprecedented constitutional powers. But even as it has achieved stunning successes, such as the eradication of smallpox, it has failed to live up to the exalted expectations of the postwar health and human rights movement e exemplified most recently by its inadequate response to the Ebola epidemic. Our aim is to offer innovative ideas for restoring the Organization to its leadership position by exercising its normative authority, even as it faces a crowded and often chaotic global health architecture. Before …

The Fertility Problem Inventory And Infertility-Related Stress: A Case Study, Staci Leigh Born

All Graduate Theses, Dissertations, and Other Capstone Projects

More than seven million people of childbearing age in the United States experience infertility. For women, the experience of infertility is stressful. The Fertility Problem Inventory (FPI) has been used to quantitatively measure women's experience of infertility-related stress. However, the construct of infertility-related stress is poorly described in existing literature. The purpose of this case study was understand how women experience the FPI as a measure of infertility-related stress. To address this issue, women who are undergoing infertility treatment completed the FPI and participated in unstructured interviews. Archival documents were also retrieved to corroborate findings and satisfy saturation. Results indicate …

She Got Her Period: Men's Knowledge And Perspectives On Menstruation, Ishwari Rajak

All Graduate Theses, Dissertations, and Other Capstone Projects

Research show that men and women often do not converse freely about menstruation. Shame, taboos and myths associated with menstruation silence the conversation. Silencing conversations about menstruation have negative consequences on women, including: objectification of women's bodies, stereotyping of women as physically, morally and emotionally inferior to men and to extreme cases women losing their uterus due to unhygienic means of menstrual management. On the one hand, not addressing menstruation openly has devastating consequences on women but on the other hand, most men seem oblivious about the impacts on women. Therefore, it is important to engage in open dialogues about …

Youth Assault-Injury Variation Patterns And Their Dimensional Structure, Diana Faissal Wilkerson

Walden Dissertations and Doctoral Studies

Youth assault-injury is 1 of the 5 leading causes of adolescents' death in the United States. Despite public health efforts, the prevalence rates of youth assault-injury and almost all its risk factors have remained consistent in the past 10 years. The purpose in conducting this cross-sectional quantitative study using archival data of the Add Health Wave II in-home survey was to examine the underlying-multidimensional structure of youth assault-injury. Problem behavior theory (PBT) lens and a multidimensional model were used and a structural equation model was conducted to examine the relationships between 22 risk and protection variables, 3 unobserved latent factors, …

Impact Of Environmental And Individual Risk Factors On Pregnant And Parenting Teenagers, Lakeasha Thrasher

Walden Dissertations and Doctoral Studies

Teenage pregnancy is both a social and a public health problem in the United States, with approximately 750,000 young women between the ages of 15 and 19 becoming pregnant each year. In addition, teen pregnancy is more prevalent in the African American (15%) and Hispanic (14%) communities than it is in White communities (5%). The purpose of this study was to identify risk factors contributing to teen pregnancy among racially diverse teenagers 15 to 19 years of age living in the rural south. This study, guided by social cognitive theory, used a quantitative, cross-sectional research design to determine whether living …

Obesity And Workplace Injury In Hazardous Occupations Among The Hispanic/Latino Population, Barbara Klyde

Walden Dissertations and Doctoral Studies

Over the past 20 years, adult obesity has increased in the United States, especially among the Hispanic/Latino population. In 2010, the Occupational Safety and Health Administration Environmental and Safety News, reported that younger workers, ages 18 to19 years of age, worked in the most high-risk occupations such as agriculture, construction, fishing, and manufacturing. The reported fatality rates for these occupations were 5.6 times greater for Hispanic workers compared to other race/ethnicity groups reported by the Bureau of Labor Statistics in 2013. This study determined whether obesity contributed to workplace injury or mortality in hazardous occupations, using federal, state, and independent …