Digital Commons Network^™

Type 2 Diabetes Mellitus (T2dm) “Remission” In Non-Bariatric Patients 65 Years And Older, Srikanth Tangelloju, Bert B. Little, Robert J. Esterhay, Guy Brock, A. Scott Lajoie

Faculty and Staff Scholarship

Objective: To analyze the factors associated with type 2 diabetes mellitus (T2DM) “remission” in non-bariatric Medicare patients 65 years and older.

Research Design and Methods: A retrospective cohort analysis of a Medicare Advantage health plan was conducted using administrative data. An individual was identified as T2DM if the individual had: ≥ 2 medical claims for T2DM coded 250.xx excluding type 1 diabetes; or ≥ 2 pharmacy claims related to T2DM; or ≥ 2 combined medical claims, pharmacy claims for T2DM in 12 months. A T2DM individual was in “remission” if they had no T2DM related claims for more than 12 …

The Inflammatory Potential Of Diet In Determining Cancer Risk; A Prospective Investigation Of Two Dietary Pattern Scores, Stina Bodén, Robin Myte, Maria Wennberg, Sophia Harlid, Ingegerd Johansson, Nitin Shivappa, James R. Hébert, Bethany Van Guelpen, Lena Maria Nilsson

Faculty Publications

Purpose Inflammation-related mechanisms may contribute to the link between diet and cancer. We sought to investigate the inflammatory impact of diet on cancer risk using the Dietary inflammatory index (DII) and an adapted Mediterranean diet score (MDS).

Methods This population-based, prospective cohort study used self-reported dietary data from the Västerbotten Intervention Programme, including 100,881 participants, of whom 35,393 had repeated measures. Associations between dietary patterns and cancer risk were evaluated using Cox proportional hazards regression. We also used restricted cubic splines to test for potential non-linear associations.

Results A total of 9,250 incident cancer cases were diagnosed during a median …

Utilization Of Media-Driven Technology For Health Promotion And Risk Reduction Among American Indian And Alaska Native Young Adults: An Exploratory Study, Todd M. Sabato

Journal of Health Disparities Research and Practice

Across the developmental spectrum, American Indian and Alaska Native (AI/AN) adolescents and young adults experience considerable behavioral and mental health disparities, including substance abuse, depression, and engagement in sexual behaviors which enhance risk of pregnancy and sexually transmitted infections. Health-focused interventions utilizing digital and media technology hold significant promise among tribal communities, as they have the capacity to eliminate geography-based barriers. Utilizing a sample of 210 self-identified AI/AN students attending tribal colleges, this study identified the most effective technologies and intervention strategies, as well as health seeking patterns and preferences, which may impact implementation and sustainable use in tribal settings. …

Identification Of Bird-Associated Nonpoint Sources Of Microbial Contamination In Sediments, Savannah D. Mullins

Honors College Theses

Fecal indicator bacteria (FIB), such as Enterococci, are commonly used to monitor the microbial contamination of recreational beach waters based on standards set by the United States Environmental Protection Agency. Sediment and sand may also harbor FIB and reintroduce these bacteria to the water column. Enterococci may be originated from various non-point sources such as humans and wildlife. Recent literature has shown that avian feces also harbor high concentrations of Enterococci. The purpose of this study is identify the relationship between Enterococci and avian-associated markers in sediments. Sediment samples were collected monthly from four sites at Kings Ferry Beach in …

Regulatory Disclosure Policies And Potential Induced Changes In Behavior: An Outcome Evaluation Of Santa Clara County’S Enhanced Food Safety Program Elements, Christian Cruz

Master's Projects

Despite countless advances in food microbiology and public health regulations, foodborne illness continues to be a major strain on public health outcomes and a costly economic burden. In the United States, many agencies are responsible for ensuring the quality of food, both domestically produced and imported. States and localities are delegated the responsibility of identifying and ensuring sound practices in the latter stages of the food production process, namely the retail distribution of food products to consumers.

Regulatory policies across the nation have only recently incorporated the evidenced-based principles of hazard risk management (Law, 2003). Still, food-related acute gastrointestinal illnesses …

Using The Consolidated Framework For Implementation Research To Investigate Daily Pre-Exposure Prophylaxis (Emtricitabine/Tenofovir Df) Implementation Via Community-Based Hiv Testing Sites In Florida, Deanne E. Turner

USF Tampa Graduate Theses and Dissertations

Background: Pre-exposure prophylaxis (PrEP) is a daily pill that can reduce a person’s chances of acquiring HIV. HIV testing and counseling is a critical point during which non-clinical staff could intervene, discuss and/or refer clients for PrEP. However, not all HIV testing/counseling staff take part in PrEP implementation in the same way. This study investigated: 1) the underlying PrEP implementation subgroups of staff who perform HIV testing and 2) PrEP implementation as a function of key constructs from the Consolidated Framework for Implementation Research (CFIR).

Methods: This study was a mixed methods concurrent triangulation design, in which qualitative and quantitative …

Understanding The Adoption Process Of An Hpv Vaccine School-Entry Requirement In Puerto Rico, Coralia Vázquez-Otero

USF Tampa Graduate Theses and Dissertations

Human Papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the US. Infection with low-risk HPV (i.e., 6 and 11) can cause genital warts, and persistent infection with high-risk HPV types (i.e., HPV 16 and 18) can progress to cancer. Currently, there is an HPV vaccine that is recommended for boys and girls, aged 11 to 12. Healthy People 2020 established a national objective of 80% completion of HPV vaccination among children aged 13 to 15 years old. Although the HPV vaccine is proven to be a safe and effective primary prevention strategy, uptake and completion rates remain …

Hour-Level Resolution On Consumption Pattern Of Substance Abuse, Jarrett Mauk, Rhiannon Huffines, Brittney Nelson, Tara Croft, Bikram Subedi

Scholars Week

Conventional survey-based approaches of determining the consumption statistics of drugs in communities are suffered from non-response biases, and typically underestimate the actual consumption. Time and cost-intensive conventional approaches, therefore, can’t be utilized to determine high-resolution temporal variability in drug consumption. In this study, the temporal trend of consumption of 10 illicit and 26 prescribed neuropsychiatric drugs was determined at hour-level resolution utilizing wastewater-based epidemiology. The hourly composite raw wastewater (every 10 minutes) samples were collected for three consecutive days in a typical week (total of 72 samples), analyzed for target drug residues using UPLC-MS/MS, and back-calculated the consumption rate of …

A Retrospective Study Of The Opioid Epidemic And Fentanyl Related Overdose Fatality Cases In A Florida West Coast Medical Examiner District Population, Anne Terese Powell

USF Tampa Graduate Theses and Dissertations

Opioids are scheduled by the propensity for misuse and abuse with a high rate of dependency and risk of fatal overdose. Opioids can be divided into different classes, including, natural, synthetic, and semi-synthetic. Opiates are naturally occurring and come directly from the opium poppy plant; whereas the semi synthetics opioids are chemical modifications of the poppy plant. Synthetic opioids attach to the opioid receptor but contain no part of the poppy plant. The increased variety and frequency in opioid prescriptions contributed to an opioid epidemic in the United States which is still on going.

According to the CDC, the opioid …

Preventing Infectious Hematopoietic Necrosis In Salmonid Fish Along The Columbia River Basin, Whitney L. Wright

OHSU-PSU School of Public Health Annual Conference

Infectious hematopoietic necrosis virus (IHNV) is a member of the Rhabdoviridae family and causes infectious hematopoietic necrosis (IHN) disease in many salmonid species during the juvenile or “fry” stage of life. IHNV is endemic to Western North America and occurs in the Columbia River Basin, where Steelhead and Chinook salmon are the most abundant IHNV-vulnerable species. IHNV can cause an epidemic in wild or farmed stocks, killing 90-95 percent of the fish it infects. Transmission is currently understood to occur by direct exposure through the gills, and the virus is shed typically from asymptomatic or clinically ill carrier adults at …

Induction Of Lipid Bodies In Leishmania Infantum-Infected C57bl/6 Macrophages Of Male Versus Female Origin, Victor A. Soupene, Ryan D. Lockard, Mary E. Wilson, Nilda E. Rodriguez

Research in the Capitol

Worldwide, 12 million people are infected with Leishmania spp. parasites. Leishmania are transmitted by the bite of sand flies. The parasite is internalized by immune cells where they develop, reproduce, and spread to new immune cells causing disease. Epidemiological studies have shown that males are more likely to develop disease. We recently demonstrated that Leishmania infantum survive better in immune cells of male origin than in cells derived from females. We also showed that L. infantum infection is characterized by fat accumulation. Additional experiments have shown that infected immune cells from males accumulate more fat than cells from females. We …

The Effects Of Stress Mindset Interventions On University Students' Health And Functioning, Abigail Fate

Undergraduate Honors Papers

In modern society, the overwhelming cultural narrative proclaims that stress is detrimental to health and should be limited and avoided at all costs. However, recent research has demonstrated that it is one’s stress mindset, rather than their stress level, that determines the psychological and physiological outcomes. Mindsets are lenses that simplify and order the world, and have been proven to influence daily behavioral and physiological responses to create cascading effects. Recent research has demonstrated that one’s mindset about stress is the demining factor in health, performance, and productivity in response to stressful conditions, and that these mindsets can be manipulated …

Maternal Health In Eastern Tanzania: Antenatal, Delivery And Postnatal Care, Christina Sego

Mahurin Honors College Capstone Experience/Thesis Projects

The purpose of this study is to evaluate maternal health conditions in eastern Tanzania and identify areas and conditions for improvement of healthcare. Tanzania is ranked 27th highest country in maternal mortality in the world (The World Factbook: Tanzania, 2018). Maternal health is an ongoing challenge Tanzania is facing as a country. This experiment was designed to identity areas of service in the district hospital setting that could advance quality of care. This study was conducted in Sinza Palestina Hospital, a district hospital on the outskirts of Dar es Salaam, Tanzania. Data was collected in the form of observation, interviews …

Effects Of Evidence-Based Materials And Access To Local Resources On Physical Activity During Pregnancy, Kolbi Edens

Masters Theses & Specialist Projects

Physical activity (PA) during pregnancy has been shown to be safe and effective for improving maternal and infant health; however, only 23% of pregnant women exercise in accordance with guidelines. PURPOSE: To determine if the distribution of evidence-based educational resources as well as access to community resources will increase PA levels as well as knowledge/beliefs about PA during pregnancy. METHODS: Participants (8-12 weeks) completed assessments concerning their activity levels, as well as knowledge/beliefs regarding PA, during pregnancy. Next, participants were randomly assigned to either an intervention (IG) or control group (CG). The IG received educational information regarding PA during pregnancy, …

(Video) Latino Immigration And Chronic Disease: A Critical Analysis Of Socioeconomic And Psychological Mediators, Frances Anne Fernando

GW Research Days 2016 - 2020

A critical analysis of chronic disease among Latino immigrants demonstrates the interplay between the individual, socioeconomic, and pathophysiological mediators of disease. To identify the major factors involved, a conceptual framework was developed to explain the relationship between Latino immigration to the US and the manifestation of diabetes and cardiovascular disease. Mediating factors include: self-efficacy, stress, social support, access to healthcare, pathophysiological risk factors and the familial and cultural environment. As the Latino population is the fastest growing and largest minority group in America, increased support among the identified factors will target interventions with broad health and economic implications for the …

Measuring The Effects Of Thc On Human Sperm Parameters Using Biomonitoring Analysis, Roxana Amaya-Fuentes, Heather Young, Courtney Irwin, Jonathan Crites, David Moody, Melissa Perry

GW Research Days 2016 - 2020

Marijuana is one of the most common substances used in the United States with more men utilizing marijuana compared to women. The effects of marijuana on the brain are well known, however, there is limited research on its effects on human sperm parameters. We examined the association between THC and human sperm parameters in participants in the Washington D.C. area. Our preliminary results suggested that THC was associated with low sperm morphology.

Background: Marijuana has a long history of human usage for medicinal, ceremonial, and religious purposes. As of January 2018, nine states including Washington D.C. have legalized it for …

Isoprene Emission Rates From Extreme Heat Exposure Due To Climatic Changes On Quercus And Populus Tree Genera: A Systematic Review, Isabella Kaser, Susan Anenberg

GW Research Days 2016 - 2020

This systematic literature review explores whether isoprene emission rates from common tree species would be exacerbated in a warming world. When isoprene reacts with other pollutants, such as nitrogen oxides, tropospheric ozone is formed. Ozone is harmful to human health and is shown to decrease lung function among many other negative respiratory effects. If the rates of emissions continue at their current levels, there may be increased rates of asthma-related ED visits and respiratory diseases among the general population.

"As Parents, How On Earth Are We Going To Handle This Issue": Provider And Parent Views On Sexuality-Related Challenges During Adolescence Among International Hiv-Infected Adoptees In The U.S., Sarah Alger, Cynthia Fair

GW Research Days 2016 - 2020

As the number of internationally adopted children with HIV has increased since 2010 in the U.S., more children may have additional educational needs, particularly related to sexuality, as they mature. After conducting 48 hour-long, semi-structured interviews with parents and providers, the qualitative analysis shows that many parents' adoption decisions are driven by faith, which can influence the child's ability to gain vital sexual education given their HIV status. Parents of internationally adopted children with HIV could benefit from the support of healthcare providers to better understand the importance of sexual and reproductive health during adolescence.

Acute Particulate Matter Exposure And Suicide In North East Asia: A Literature Review, Shannon Haines, Lance Price, Amanda Northcross

GW Research Days 2016 - 2020

A systematic literature review was conducted on research exploring the relationship between acute exposures to ambient particulate matter and changes in suicide rates in North East Asian countries. From the eight studies analyzed limited evidence was found and additional research about the association is suggested.

Environmental Health Sciences In A Translational Research Framework: More Than Benches And Bedsides, Joel D. Kaufman, Cynthia L. Curl

Public and Population Health Faculty Publications and Presentations

Background: Environmental health scientists may find it challenging to fit the structure of the questions addressed in their discipline into the prevailing paradigm for translational research.

Objective: We aim to frame the translational science paradigm to address the stages of scientific discovery, knowledge acquisition, policy development, and evaluation in a manner relevant to the environmental health sciences. Our intention is to characterize differences between environmental health sciences and clinical medicine, and to orient this effort towards public health goals.

Discussion: Translational research is usually understood to have evolved from the bench-to-bedside framework by which basic science transitions to clinical treatment. …

The Disparity Between Scientific Consensus And American Public Opinion Of Genetically Modified Organisms And Genetic Engineering, Matthew A. Cherubino

Student Publications

Genetically modified organisms (GMOs) and genetic engineering (GE) are accepted as safe and useful by the consensus of the scientific community. Their diverse utility has shown promise in addressing major challenges of the 21st century, including world hunger, global warming, and the prevalence of diet-related diseases (e.g. heart disease, cancer, diabetes, etc.). A 2014 Pew Research Center survey revealed that while 88% of scientists agreed that GM foods were safe to eat, only 37% of American consumers agreed. Furthermore, only 35% of U.S. adults trusted scientists to accurately inform the public about GMOs. To explain this disparity, I synthesize information …

Spatial Analysis Of Exposure To Soil Heavy Metals, Oral Bioaccessibility And Risk Assessment In Houston, Texas, Tsai Shu Chu

Dissertations and Theses (Open Access)

Chronic exposure to heavy metals could lead to adverse health effects such as cancer, neurological development diseases and immunological diseases. The ingestion pathway has been considered the major exposure route for heavy metal contaminated soils. Heavy metals may be proportionally bioaccessible for the human body to absorb. There are no risk assessment studies done in Houston to evaluate health risks from exposure to heavy metals and no spatial analysis done yet. The aims of this dissertation are (1) to characterize 13 heavy metals: magnesium (Mg), vanadium (V), chromium (Cr), manganese (Mn), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu), zinc …

Stochastic Search Variable Selection Applied To A Bayesian Hierarchical Generalized Linear Model For Dyads, Adriana Lopez Ordonez

Dissertations and Theses (Open Access)

In behavioral science research, many outcomes of interest can be influenced by interpersonal relationships (Gyarmathy & Neaigus, 2007). To assess such outcomes, data can be collected using dyads. Each dyad has two elements, an actor, who responds to a stimulus and a partner, who can potentially influence the actor (Kenny, Kashy, & Cook, 2006). One popular model for analyzing dyadic data is the Actor Partner Interdependence model (APIM). In this study, we proposed a variable selection method applied to a probit Bayesian Hierarchical Generalized Linear Model (Bayesian HGLM) to fit the APIM to dyadic data. The proposed method used stochastic …

Redefining Burnout: Exploring Common Conceptualizations And The Neurophysiology Of Chronic Stress To Establish An Integrated Allostatic Model, Danny A. Guzzi

Dissertations

Burnout is a widely researched stress-related phenomenon associated with numerous adverse outcomes for employees and organizations. Unfortunately, burnout is not well understood and research to this point has been flawed due to a lack of consensus on the definition, dimensionality, and context of the construct. Prevalent conceptualizations of burnout have been criticized for being arbitrarily developed without solid theoretical foundation and for failing to clearly distinguish burnout from depression or other work-related conditions such as compassion fatigue, secondary traumatization, and vicarious traumatization. The current project first examines relevant literature to identify commonalities among prevalent burnout conceptualizations. Then relevant stress research …

Is Breastfeeding Truly Best? Evolutionary, Physiological, & Cultural Factors That Shape Breastfeeding Practices, Emily J. Green 19

Honor Scholar Theses

No abstract provided.

Randomized Pilot Trial For A Community-Based Group Stretching Exercise Program For Chronic Low Back Pain, Marc Brodsky, Ann Hansen, Wendy Bjerke

Exercise Science Faculty Publications

Background: Authors of meta-analyses concluded that exercise therapy appears to be slightly effective at decreasing pain and improving function in adults with chronic low back pain (CLBP), particularly in health-care populations. Similar to health-care settings, community organizations provide wellness and lifestyle modification programs. Different versions of the Young Men’s Christian Association (YMCA) Y’s Way to a Healthy Back program were offered from 1974 to 2004. Champions of the YMCA program and authors of the pilot study designed a Healthy Back Curriculum to update and reintroduce the program. Objective: The research aim of this randomized pilot trial was to investigate the …

Identifying Predictors Of Racial Disparity In Treatment And Mortality Among Patients Diagnosed With Breast Cancer In South Carolina, Oluwole Adeyemi Babatunde

Theses and Dissertations

Introduction: Despite a lower incidence of breast cancer (BrCA) among Black women in the U.S. compared to White women, Black women experience consistently higher mortality rates. The aims of this study were 1) to assess the relationship between race and diagnosis-to-treatment times 2) to assess racial disparity in mortality among Black and White BrCA patients in SC and 3) assessment of the validity of the Mortality-to- incidence ration (MIR) as a proxy for survival and geospatial investigation of racial disparity among breast cancer (BrCA) patients.

Methods: Breast cancer cases diagnosed between 2002-2010 were obtained retrospectively from the SC Central Cancer …

Factors Associated With Rapid Repeat Pregnancy Among Women In A Healthy Start Program In Kent County, Michigan, Sarah Jane Schmidt

Masters Theses

Strong Beginnings (SB) is a federal Healthy Start Program aiming to improve the health and well-being of black and Hispanic families by promoting racial equity and eliminating racial disparities in birth outcomes, including rapid repeat pregnancy (secondary pregnancy within 18 months of index birth). To better prevent the occurrence of rapid repeat pregnancy (RRP), this study explores individual, social, and environmental factors associated with RRP. De-identified data for this study included information from SB, the Maternal Infant Health Program, Medicaid claims, and birth certificates. The sample includes women enrolled in SB with an index birth between 2013 and 2015. Chi-square …

Quality Over Quantity: A Comparative Analysis Of The Quality Measures And Performance Between Switzerland And The United States, Lexi Farina

Independent Study Project (ISP) Collection

Even in the best health systems, poor quality of care continues to cause harm to patients and prevent them from receiving the best treatment possible. Thus, it is important to record and report quality of care measures because they can help inform policy changes and improve performance. In this paper, a comparative analysis between the United States and Switzerland is conducted to understand the process for defining and assessing quality indicators in each country as well as compare their quality of care performance results. The methods for this study include a literature review of relevant background information relating to quality …

My Body, Their Choice: Childbearing Attitudes And Practices In Jamkhed, Maharashtra, Sienna Sewell

Independent Study Project (ISP) Collection

Understanding the beliefs and practices of women and their families during pregnancy and childbirth is fundamental to the creation of successful public health interventions that target maternal and infant mortality. This study explores the childbearing practices of women in rural Jamkhed, as well as the social and economic factors that influence family planning, reproductive health-seeking, and delivery. Interviews and quantitative surveys were conducted with women in villages that have partnered with the Comprehensive Rural Health Project (CRHP) to examine how and why women access prenatal care during pregnancy. The influence of CRHP’s “Jamkhed Model” on healthcare access is considered in …