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In Vitro And In Vivo Toxicological Evaluation Of Emissions From The Fused Filament Fabrication Three-Dimensional Printing, Mariana T. Farcas

Graduate Theses, Dissertations, and Problem Reports (ETD)

Fused filament fabrication (FFF), a three-dimensional (3-D) printing process, is an emerging technology that has recently gained wide popularity among both consumers and manufacturers. As filament is heated to above its glass transition temperature in a 3-D printer, a portion may undergo thermal decompostion, which releases ultrafine particles (UFP) and volatile organic compounds (VOCs) with potential adverse respiratory health effects are released into the air. This study's central hypotheses is that emissions generated during 3-D printing are toxic and exposure to these emissions induces pulmonary and systemic adverse health effects. Considering that currently, limited understanding is available on the health …

Quantification Of Bacterial Shedding From The Respiratory Tract Of Health Care Workers Wearing Paprs And Other Types Of Air-Purifying Respirators On Sterile Conditions In A Simulated Operating Rooms (Ors), Segun Olanrewaju Ajewole

Graduate Theses, Dissertations, and Problem Reports (ETD)

The role of powered air- purifying respirators (PAPRs) in healthcare settings during infectious diseases outbreaks and highly contagious pathogens (e.g., SARS, HINI, Ebola, COVID etc.) has attracted much interest based on the level of respiratory protection they provide and their many positive user features. A common practice among healthcare workers to minimize airborne contaminant exposure has been to use surgical masks or N95 filtering facepiece respirators (FFRs). Surgical masks have been shown to offer minimal respiratory protection and while N95 FFRs offer better respiratory protection, they are not comfortable to use for a prolonged period. With current PAPR designs, exhaled …

Social Determinants And Academic Success For Online Undergraduates Mediated By Mental Health, Jamie Michelle Claus Getz

Walden Dissertations and Doctoral Studies

AbstractSocial determinants of health (SDH) are social and economic systems that directly contribute to health disparities and inequalities. This study examined SDH and their relation to education, also an SDH. The relationship between SDH and online undergraduate achievement, as measured by grade-point average (GPA), was studied. Cumulative inequality is the theoretical framework that guided the study; it underscores the complexity of interaction between personal, social, and environmental stressors in relation to a student’s academic performance. The quantitative survey design allowed for potential relationships between variables to be observed and studied based on the survey responses per self-report from 212 online …

Social Ecological Factors Affecting Marijuana Use Among Young Adults In The United States, Temple Oritsegbubemi Jagha

Walden Dissertations and Doctoral Studies

AbstractCurrent knowledge of young adults’ marijuana use centers around individual risk factors and negative health effects (i.e., mental disorder), with less focus on contextual circumstances. In this study, I examined the association between demographic (i.e., gender, race, education, employment, income, and population density), social (i.e., risk perception and religious beliefs influence), living context (i.e., difficulty getting marijuana, poverty level, and county metro status), and marijuana use among young adults. The social-ecological model guided this study. In this quantitative cross-sectional study, data from the 2019 U.S. National Survey on Drug Use and Health that included 14,226 young adults aged 18 to …

Association Between Asymptomatic Malaria Infection And Pregnancy Outcome In Delta State, Nigeria, Sadiatu Sally Obi

Walden Dissertations and Doctoral Studies

Pregnant women are vulnerable due to the pregnancy-induced suppressed immunity in malaria-endemic areas. Asymptomatic malaria in pregnancy (MiP) threatens both the mother, fetus, and neonate via chronic placental malaria which impacts maternal-neonatal exchange. Some studies reported that MiP risk factors vary across locations, however, there are few studies on MiP and pregnancy outcome in Nigeria. The purpose of this study was to investigate the association between asymptomatic placental malaria infection and pregnancy outcome among parturients in Asaba, Delta State, Nigeria. This study was developed with a quantitative methodology that utilized primary and secondary healthcare data from 483 subjects aged 18–49 …

Relationship Between Cultural And Religious Practices And Ebola Virus In Freetown, Sierra Leone, Richmond Samuel Kpange

Walden Dissertations and Doctoral Studies

The 2014 Ebola virus epidemic in the West Coast of Africa was a historically unprecedented epidemic with a sustained spread in multiple West African nations, including Sierra Leone. The World Health Organization (WHO) classified Sierra Leone as a high Ebola-affected country as it reported the highest number of deaths (14,124) during the last Ebola outbreak compared to other Ebola-affected countries. Public health experts have given little attention to the impact of sociocultural factors on infectious diseases, especially Ebola. The purpose of this study was to ascertain whether there is a relationship between the spread of EVD and a patient’s gender, …

Relationship Between Cultural And Religious Practices And Ebola Virus In Freetown, Sierra Leone, Richmond Samuel Kpange

Walden Dissertations and Doctoral Studies

The 2014 Ebola virus epidemic in the West Coast of Africa was a historically unprecedented epidemic with a sustained spread in multiple West African nations, including Sierra Leone. The World Health Organization (WHO) classified Sierra Leone as a high Ebola-affected country as it reported the highest number of deaths (14,124) during the last Ebola outbreak compared to other Ebola-affected countries. Public health experts have given little attention to the impact of sociocultural factors on infectious diseases, especially Ebola. The purpose of this study was to ascertain whether there is a relationship between the spread of EVD and a patient’s gender, …

Living In An Oil-Polluted Region In Nigeria As A Risk Factor In Colorectal Cancer Development, Steve Nwachi Onya

Walden Dissertations and Doctoral Studies

Due to differences in exposure to various risk factors, colorectal cancer (CRC) rates differ in regions of Nigeria. Although the people living in the Southsouth, an oil-producing region, are concerned that they are most affected, there is insufficient research to address these concerns. The purpose of this quantitative ecological study was to investigate whether living in the oil-polluted region in Nigeria is associated with an excess CRC incidence rate. The potential spatial autocorrelation of CRC incidence among the contiguous regions was also examined. The study was grounded in the ecosocial theoretical framework. Data were extracted from the Nigeria National System …

Comparison Between The Prevalence Of Probable Post-Traumatic Stress Disorder Among Different Flood Types In Thailand, Natakorn Ritbunyakorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

Floods are one of the most common natural disasters in Thailand. Floods may have a long-term psychological impact on survivals. Post-traumatic stress disorder (PTSD) usually diagnosed among flood victims. However, there is limited information on PTSD from different flooding events in Thailand. This study aimed to determine the prevalence and associated factors of having probable PTSD among different flood types in Thailand. A secondary data analysis was performed using a dataset from previous cross-sectional survey conducted from 2019 to 2020 in Nakhon Sawan and Nakhon Si Thammarat provinces selected from the expert reviews’ discussion. The analysis was performed on 376 …

Association Between Prepregnancy Obesity And Health Behaviors, Adverse Conditions, And Birth Outcomes In South Dakota, Lily Sanderson

Electronic Theses and Dissertations

Introduction: Prepregnancy obesity is associated with an increased risk for various adverse outcomes for mother and fetus. These adverse associations exist within the realms of preconception health, prenatal health, birth outcomes, and postnatal health.
Methods: This retrospective cohort study used data from the South Dakota Pregnancy Risk Assessment Monitoring System (SD PRAMS) survey, which is an ongoing statebased surveillance system of maternal behaviors, attitudes, and experiences before, during, and shortly after pregnancy. The 2017 and 2018 SD PRAMS sampled a total of 3,805 mothers who were randomly selected from birth certificate records to be representative of all South Dakota women …

Risk Factors For Foodborne Illness Outbreaks In Retail Food Establishments, Brendalee Viveiros

Walden Dissertations and Doctoral Studies

Despite policies and interventions over the last two decades, foodborne illness remains a significant public health concern. According to the CDC’s Foodborne Disease Outbreak Surveillance System, 60% of reported foodborne illness outbreaks involved food that was prepared at a restaurant. Reducing foodborne illness outbreaks that occur at restaurants would have a significant impact on the overall number of foodborne illnesses that occur each year. The purpose of this study was to quantitatively analyze the differences in risk factors in food establishments that have had a foodborne illness outbreak compared to food establishments that have not. This study used Reckwitz’s theory …

Disparities In The Use Of Radiation Therapy For Postlumpectomy Breast Cancer, Deborah Rothley

Walden Dissertations and Doctoral Studies

Early-stage breast cancer can be highly curable when properly treated using national standards of care. However, disparities in treatment, including radiation therapy after lumpectomy, may result in disproportional mortality rates in African American women. The purpose of this study was to add to the body of research to help determine the reasons for an underutilization of radiation therapy among African American women and whether the disparity has continued by analyzing recent patient data. Anderson’s behavioral model was used to frame the study and help determine the associations between the predisposing and enabling independent variables of race, age, health insurance status, …

Psychosocial Factors And Physical Health In Chronic Obstructive Pulmonary Disease Patients, Olulana Bamiro

Walden Dissertations and Doctoral Studies

The research problem identified was poor physical health in older adults with chronic obstructive pulmonary disease (COPD). The problem is important because poor physical health yields unsuccessful aging. The current research aimed to identify psychosocial factors that improve self-evaluated physical health in the study population as a proxy to overall health; the research questions helped identify these factors. The first research question assessed the association between health locus of control and self-evaluated physical health. The second research question evaluated the association between family support and self-evaluated physical health. A final research question assessed the association between health locus of control, …

Comparing Melatonin Use To Bright Light Therapy In Mitigating Cardiovascular Effects Due To Shift Work Disorder In Shift Working Adults, Alexandra Hirt

Capstone Showcase

Introduction: Circadian Misalignment is a term used to describe a mismatch in one’s physiologically determined sleep patters and their actual sleep wake behaviors. Shift workers often end up in a vicious cycle of being in a state of chronic circadian misalignment, which then can lead to health problems, extreme fatigue, and insomnia, known as Shift Work Disorder (SWD).This has been studied in night shift workers who, when compared to daytime workers, have an increased risk of developing metabolic syndrome, type 2 diabetes, and coronary heart disease.These results are not dependent on any behavioral risk factors, such as smoking and poor …

Reducing Disease Exacerbation In Women With Confirmed Copd: A Systematic Literature Review, Jill Essay

All Graduate Theses, Dissertations, and Other Capstone Projects

Abstract

A systematic literature review was conducted to establish whether gender specific treatment exists for patients with Chronic Obstructive Pulmonary Disease (COPD), specifically, women with (COPD). The PICO question developed for this review is as follows: In women with confirmed diagnoses of COPD, does gender-specific treatment, compared to standard treatment, impact the frequency of exacerbations? Could the number of COPD exacerbations in women be reduced by incorporating interventions designed with (female) gender in mind? Four databases were included in the search: CINAHL, Pubmed, Medline, and Nursing and Allied Health. Articles included addressed gender differences in relation to the disease process, …

Analysis Of Circadian Rhythm Irregularities On The Health Of Shift Workers, Sahil Rajan

Williams Honors College, Honors Research Projects

Circadian rhythms involve the natural 24 wake-sleep cycle that governs proper maintenance of biological sleep schedules. Circadian rhythm disruption has been associated with health issues such as diabetes, obesity, and mental health disorders such as bipolar and sleep disorders. In this study, a survey method was utilized in order to analyze specific population demographics to determine whether working day or night shifts predisposed individuals to health issues due to disruptions in their circadian rhythms. This study was also carried out to observe popular coping strategies among night shift workers. Of all the variables tested comparing the difference between day and …

Genetic Risk Factors For Alzheimer’S Disease In Racial/Ethnic Minority Populations In The U.S.: A Scoping Review, Lindsey Rubin, Lucy Annang Ingram Phd, Nicholas V. Resciniti, Brianna Ashford-Carroll, Katherine Henrietta Leith, Aubrey Rose, Stephanie Ureña, Quentin Mccollum, Daniela B. Friedman

Faculty Publications

As the United States (U.S.) population rapidly ages, the incidence of Alzheimer's Disease and Related Dementias (ADRDs) is rising, with racial/ethnic minorities affected at disproportionate rates. Much research has been undertaken to test, sequence, and analyze genetic risk factors for ADRDs in Caucasian populations, but comparatively little has been done with racial/ethnic minority populations. We conducted a scoping review to examine the nature and extent of the research that has been published about the genetic factors of ADRDs among racial/ethnic minorities in the U.S. Using an established scoping review methodological framework, we searched electronic databases for articles describing peer-reviewed empirical …

Restriction Of Access To Deep Brain Stimulation For Refractory Ocd: Failure To Apply The Federal Parity Act, Rachel Davis, James Giordano, D Brian Hufford, Sameer A. Sheth, Peter Warnke, Alik S. Widge, R Mark Richardson, Joshua M. Rosenow, Peter Justin Rossi, Eric A. Storch, Helena Winston, Joanne Zboyan, Darin D. Dougherty, Kelly D. Foote, Wayne K. Goodman, Nicole C. Mclaughlin, Steven Ojemann, Steven Rasmussen, Aviva Abosch, Michael S. Okun

Faculty Publications

No abstract provided.

Molecular Identification Of Parasites In An Intestinal Coprolite From A Mummified Religious Dignitary Of The Piraino Mother Church Crypt, Sicily, Amanda Rollins, Krystiana Krupa, Georgia Millward, Dario Piombino-Mascali, Karl Reinhard, Frederika Kaestle

Karl Reinhard Publications

Intestinal contents were sampled from a spontaneously enhanced mummy from the Sepulcher of the Priests of the Piraino Mother Church in the Province of Messina, Sicily. This adult male mummy, Piraino 1, is an unidentified religious dignitary dating from the late-18th to mid-19th centuries. Immunological and molecular diagnostics were used to test for common and clinically significant parasites. A morphological diagnosis of Trichuris trichiura (whipworm) was confirmed genetically. A previously undetected Enterobius vermicularis (pinworm) infection was also identified genetically. These data indicate that the Piraino 1 individual was simultaneously infected with multiple intestinal parasite species indicative of poor hygiene. This …

Nutritional Approach For Increasing Public Health During Pandemic Of Covid-19: A Comprehensive Review Of Antiviral Nutrients And Nutraceuticals, Vahideh Ebrahimzadeh-Attari, Ghodratollah Panahi, James R. Hébert Scd, Alireza Ostadrahimi, Maryam Saghafi-Asl, Neda Lotfi-Yaghin, Behzad Baradaran

Faculty Publications

Background: The novel coronavirus (COVID-19) is considered as the most life-threatening pandemic disease during the last decade. The individual nutritional status, though usually ignored in the management of COVID-19, plays a critical role in the immune function and pathogenesis of infection. Accordingly, the present review article aimed to report the effects of nutrients and nutraceuticals on respiratory viral infections including COVID-19, with a focus on their mechanisms of action.

Methods: Studies were identified via systematic searches of the databases including PubMed/ MEDLINE, ScienceDirect, Scopus, and Google Scholar from 2000 until April 2020, using keywords. All relevant clinical and experimental studies …

Prevalence And Health Burden Of Cardiovascular Disease In Older U.S. Veterans: Results From The 2019-2020 National Health And Resilience In Veterans Study, Cailin Arechiga

Public Health Theses

Importance. Cardiovascular disease (CVD) is one of the leading causes of death in the U.S. and is associated with a range of demographic, military, trauma, and clinical characteristics and physical and mental health conditions. Older military veterans may have an increased risk for CVD, given their advanced age and military experiences. However, the prevalence and health burden of CVD in population-based samples has not been well characterized. Objective. To characterize the current prevalence of CVD, and its association with sociodemographic, military, trauma, and clinical variables in a large, contemporary, and nationally representative sample of older U.S. veterans. Design. Cross-sectional study …

United States Long-Term Trends In Adult Bmi From 1959 To 2018 By Income, Education, And Race/Ethnicity, Julia Banas

Public Health Theses

Obesity prevalence has increased dramatically since the 1950s. While cross-sectional comparisons across racial, ethnic, and socioeconomic groups are abundant, there is less work on long-term trends. We assessed trends in average adult body mass index (BMI) in the United States by income, education, and racial/ethnic groups from 1959 to 2018 using the National Health and Nutrition Examination Survey, which assesses repeated cross-sectional, representative samples of the United States population. Height, weight, income, education, and race variables were extracted from raw data files; income data was converted to constant dollars prior to analysis. BMI was calculated from height and weight measurements. …

Healthcare Provider Perspectives On The Influence Of Cultural Beliefs On Infant And Young Child Feeding Practices Within Ghanaian Refugee Camps: A Qualitative Analysis, Morgan Nadene Veronica Buchanan

Public Health Theses

Adherence to breastfeeding and complementary feeding recommendations is a proven strategy for promoting the well-being of infants and young children and ensuring their proper development. Cultural beliefs inform caregivers’ likelihood to follow these guidelines as they influence caregivers’ thoughts about maternal behavior during the prenatal and lactation periods, child feeding behaviors, and health. Refugee camps or settlements are a unique space to study the coexistence of cultural beliefs held by residents and staff. Understanding the pathways by which cultural beliefs modulate caregiver infant and young child feeding (IYCF) behavior (and therefore impact child health) within these settings is of paramount …

Quantification Of Anesthetic And Analgesic Compounds In E-Liquids And Their Aerosols, Deyri Sugey Garcia

Public Health Theses

The unprecedented rise of vaping has resulted in gaps of scientific understanding of the health hazards this new phenomenon has created, as well as delayed regulations surrounding vape products, including coolants. Coolants are additives that create anesthetic, physical sense-reducing, and/or analgesic, properties that numbs the airways and add a minty flavor to vape products. However, it is unclear how much coolant is added to vape products electronic liquid (e-liquid), and how much of this content carries over into the aerosolized vaped form. To determine compositional analysis and carryover of common synthetic coolants, eugenol in 35 clove e-liquids and menthol, methone, …

Factors Associated With Early Childhood Development Outcomes For Children Of Adolescent And Young Adult Mothers In Brazil, Lily Benson Kofke

Public Health Theses

Objectives: A descriptive analysis to explore the risks for early childhood development (ECD) delays among children of adolescent and young adult mothers in Brazil. Methods: A secondary analysis of cross-sectional data of a representative sample of children under age 2 and their mothers from community health centers in Brasília, Brazil. The Denver Developmental Screening Test II was used to assess overall and domain-specific ECD (personal-social, fine motor, gross motor, and language). Mothers were subset into two groups based on age. Bivariate analyses and multivariable logistic regressions were used to examine the associations between maternal age and risk of ECD delay, …

Gene-Gene Interactions Contributing To Asthma Susceptibility, An Exploration Using Uk Biobank Dataset, Yuyuan Lin

Public Health Theses

Background: Previous studies have attempted to identify gene-gene interactions for asthma. However, most of these studies suffered from lack of replication or insufficient statistical power. In this study, we aimed to explore the gene-gene interactions affecting asthma susceptibility and tried to replicate the results. Both the discovery and replication datasets were nested in UK Biobank data.

Methods: Nested case-control design was used. In the discovery analysis (N= 306,859, cases = 35,483, controls = 271,376), Univariate genome-wide association analysis was performed to prioritize loci for the interaction analysis. Pairwise search for epistasis was conducted among 5,389 SNPs. Replication of the top …

The Impact Of Ww’S Multi-City Fvrx Program On Children, Damaris Lopez Mercado

Public Health Theses

Introduction and background: Higher F&V intake are associated with healthier BMI in children, but cost of F&V has been found to be a barrier to access for some families. To mitigate this barrier, Wholesome Wave (WW) implemented a six-month F&V incentive program that included a $25 weekly financial incentive for families to spend on F&V in three U.S. cities. The primary objectives of this paper are to assess whether this program significantly impacted child F&V consumption and child anthropometry from baseline to end-of-program and to assess whether F&V intake and food insecurity and end-of-program are significant predictors of healthy child …

Co-Distribution Of Ambient Light At Night And Incidence Of Human Cancers And Covid-19, Yidan Meng

Public Health Theses

Introduction and BackgroundThere are increasing concerns about the effects of artificial lights on human health, including hormone-related disease and immune functions. In January 2020, the outbreak of COVID-19 disrupted everyone’s life, and people who infected have various severity. Thus, we want to analyze whether people exposed to different ambient light at night (LAN) levels make them more susceptible to COVID-19 for our summer research. Besides the effects of LAN on immune functions, we also discussed the association of LAN and multiple cancers in seven states of Northeastern U.S. We used similar statistical and geographic analysis methods and separate them into …

Genetic Determinants For Cancer Risks With Racial Differences And Asthma, Yinqiao Wang

Public Health Theses

Over the past decade, many studies have found disproportionally higher prostate cancer among men of African ancestry, and testicular cancer incidences among men of European ancestry, compared with men from other ethnicity/race groups. However, genetic determinants that could potentially explain this observation are unclear. This study collected single nucleotide polymorphisms (SNPs) related to the two cancer types and compared the frequencies of each risk allele of SNPs among men of African or European ancestry from several genetic databases. When comparing the frequencies of risk alleles that are associated with prostate and testicular cancers, significant differences were found between those of …

Identification Of Genetic Factors For Metabolically Healthy Obese And Metabolically Obese Normal-Weight, Junli Zhu

Public Health Theses

Though obesity is typically associated with metabolic dysfunction and cardiometabolic diseases, there are both obese individuals who have favorable metabolic profiles (metabolically healthy obese; MHO) and individuals who present obesity alterations despite their normal weight (metabolically obese normal weight; MONW). Genetic studies suggest that there is a genetic component underlying these phenotypes. However, previous research has been restricted by the use of the candidate gene approach, limited choice of metabolic indicators, and low statistical power. A genome-wide association (GWA) study that examines both MHO and MONW in a single large-scale population cohort is necessary to uncover the genetic determinants of …