Digital Commons Network^™

The Effects Of The Transition From Pre-Nursing To Nursing On Mental Health, Andrew J. Davis, Paige R. Mullins, Kimberly A. Sell

Undergraduate Honors Theses

Mental health is an ever-growing crisis among adolescents and young adults, with suicide as second leading cause of death and the number of those negatively affected continually on the rise. Transitions are one of the major stressors prevalent among these age groups, placing individuals at risk for mental health deficits. This quantitative voluntary response comparative study assesses the transitional mental health of pre-nursing students and students in the nursing program at East Tennessee State University. Emailed to all with a declared major of pre-nursing or nursing, this study measured mental health using evidenced based assessment tools. The PHQ-9 for depression …

Drug-Facilitated Sexual Assault At The University Of Arkansas, Barrett Weidman

Chemical Engineering Undergraduate Honors Theses

This work was written to fulfill two main purposes. First, to help survivors of Drug-Facilitated Sexual Assault (DFSA) process their experience by compiling the toxicological, pharmacological, and distribution of the three most used date-rape drugs. Second, to gauge the knowledge and interest of University of Arkansas students regarding drug impairments, sexual assault education, and bystander intervention training. A survey was conducted for the latter and revealed that 91.6% of students believe the University’s existing sexual assault prevention education and bystander intervention training have room for improvement. Also, 37.1% of students who have received this education report that the programming does …

Cyclic-Di-Gmp-Binding Proteins Regulate Acinetobacter Baumannii Motility, Gabriel Smith

Undergraduate Honors Theses

Acinetobacter baumannii is a prevalent nosocomial pathogen where, like many other infectious bacteria, A. baumannii is increasingly considered a multi-drug resistant pathogen. This research study was designed to find a way to affect the persistence of A. baumannii such that it can be applied to a hospital setting to prevent further nosocomial infections. One regulatory mechanism potentially used by A. baumannii to persist on hospital surfaces is through the use of the bacterial second messenger cyclic-di-GMP (c-di-GMP). This nucleotide signal is regulated in response to environmental conditions, and then activates c-di-GMP-binding proteins that induce phenotypic changes. One c-di-GMP-regulated phenotype is …

Injection Drug Users (Idus), Blood-Borne Diseases, And The Role Of Needle Exchange Programs, Lilibeth Guzman

Electronic Theses, Projects, and Dissertations

Objective: Needle exchange programs are designed to educate injection drug users of healthy drug behaviors and establish a controlled environment to prevent blood-borne diseases through clean needles and provide treatment to reduce blood-borne diseases and become drug-free. This study observed the prevalence of blood-borne diseases among injection drug users as well as the general population. The study used publicly available data of drug use to assess differences by race/ethnicity, and participation in needle exchange programs.

Methods: Quantitative methods were used with the 2019 National Survey on Drug Use and Health. Analysis began with descriptive statistics, followed by regression analyses to …

From Zero To Thrive: A Model Of Cross-System And Cross-Sector Relational Health To Promote Early Childhood Development Across The Child-Serving Ecosystem, Alison L. Miller, Sara F. Stein, Rebeccah Sokol, Rachel Varisco, Phoebe Trout, Megan M. Julian, Julie Ribaudo, Joshua B. Kay, Natasha V. Pilkauskas, Nicole Gardner-Neblett, Todd I. Herrenkohl, Kara Zivin, Maria Muzik, Katherine L. Rosenblum

Articles

Early relational health between caregivers and children is foundational for child health and well-being. Children and caregivers are also embedded within multiple systems and sectors, or a “child-serving ecosystem”, that shapes child development. Although the COVID-19 pandemic has made this embeddedness abundantly clear, systems remain siloed and lack coordination. Fostering relational health amongst layers of this ecosystem may be a way to systematically support young children and families who are facing adversity. We integrate theory, examples, and empirical findings to develop a conceptual model informed by infant mental health and public health frameworks that illustrates how relational health across the …

Sleep Health And Academic Performance During The Covid-19 Pandemic: A Cross-Sectional Analysis, Rushil Gumasana

Electronic Theses, Projects, and Dissertations

Background: Sleep health is an important public health topic that is often overlooked by college students who are trying to juggle between school, work, and social life. Sleep is seen as a luxury and as a result, most often sacrificed for other activities. The purpose of this thesis is to make a connection between the factors that lead to poor sleep quality and its influence on academic performance.

Methods:The study utilized the cross-sectional approach to evaluate sleep health and identify the relationship that exists with academic performance among college students. All data were collected virtually and kept anonymous. All …

Sexual Health Services During The Covid-19 Pandemic, Thomas C. Roland

Electronic Theses, Projects, and Dissertations

Background: The COVID-19 pandemic created a unique situation for healthcare providers worldwide. The highly infectious nature of the COVID-19 virus required many countries to impose strict lockdowns and limit access to select health services such as sexual health services. The present study was designed to explore the role of the COVID-19 pandemic on healthcare services, specifically sexual health services.

Methods: A cross- sectional study design was selected to evaluate the burden of the pandemic on sexual health services. Participants responses were obtained anonymously using an online survey. Data was analyzed through descriptive statistics and bivariate analyses using IBM SPSS version …

Promoting Health Equity Among Racial And Ethnic Minorities During And After The Covid-19 Pandemic, Alexandra Viramontes, Deserry Salgado

Electronic Theses, Projects, and Dissertations

Racial and ethnic minorities experience disproportionate health outcomes during a pandemic, yet preparedness plans have failed to address the social determinants of health that produce the most severe impact. By examining social workers’ perspectives on the health disparities faced by racial and ethnic minorities during the COVID-19 pandemic, this study provides insight into the ways in which services can be improved in a future health crisis. In this exploratory study, a qualitative approach was utilized where social workers were asked to participate in interviews consisting of open-ended questions. The qualitative data was obtained in the form of interview transcripts, which …

Evaluating First Responder Personal Preparedness In Douglas County, Nebraska's Volunteer Fire And Emergency Medicine Service, Kylie Johnson

Capstone Experience: Master of Public Health

In disaster response, it is essential for first responders to focus on their disaster role. Lack of personal preparedness at home could hinder a responder’s ability to focus their attention on their response role (13). Personal conflict, such as that caused between family duties and response duties, in a disaster can be mitigated through several means. One mitigation tactic is preparedness education and support offered by the responder’s organization. While the importance of responder personal preparedness cannot be understated, there is a lack of baseline data on the topic related to Nebraska responders.

To assess the state of first responder …

Weight Gain Trajectory Over Five Years For Adult Primary Care Patients In Nebraska, Elizabeth M. Morris

Capstone Experience: Master of Public Health

INTRODUCTION: The continued rise in the prevalence of adult obesity in the United States is a public health concern. Several studies have identified the increasing rates of obesity, its impacts, and the factors leading to obesity. Some researchers have made obesity prevalence projections at the national and state levels. This study aims to fill the critical gap in real-time weight data trends among primary care adult patients in Nebraska. The main goal of this study is to determine and analyze the weight trajectory of adults in Nebraska over the past five years and determine if the trends vary among age …

Developing A Curriculum To Combat Loneliness As A Public Health Concern In Businesses, Sophia Yelkin

Capstone Experience: Master of Public Health

Loneliness has been considered a public health epidemic affecting people across the world. Elderly populations have historically been considered most at risk for loneliness, but it is becoming evident that loneliness is not so selective. Younger generations show more signs and symptoms of loneliness than older generations. This often overlooked condition is attributable to decreased mental and physical health and can weaken performance in the workplace.

This capstone project creates a concise curriculum addressing loneliness for dissemination in the workplace, ensuring appropriate health literacy for the priority population. Understanding the pervasive nature of loneliness, identifying symptoms, and methods to counteract …

A Walk In Two Worlds: An Indigenous Health Research Mentorship Model Developed From The Experiences Of Mentors And Mentees In A Cancer Research Education Program Aimed At Increasing Representation Of American Indians/Alaska Natives In Cancer Research And Healthcare Professions, Kiana Borengasser, Aislinn C. Rookwood, Joyce C. Solheim, Maurice Godfrey, Karen Taraszka Hastings, Keyonna King, Hannah Robbins, Mariah Abney, Rudy Smith Jr., Liliana Tamayo, Regina Emily Robbins

Capstone Experience: Master of Public Health

The National Cancer Institute promotes workforce development programs that aim to increase representation of American Indian/Alaska Natives in health science and research careers. One such program, Youth Enjoy Science at the University of Nebraska Medical Center, has employed American Indian/Alaska Native youth in mentored cancer research internships from 2017 to 2022. The primary purpose of this study was to examine mentor and mentee experiences of participation in Youth Enjoy Science research education internships to learn from their stories. We conducted semi-structured interviews with current and former Youth Enjoy Science mentees (n=8) and mentors (n=8). We analyzed and collectively re-storied the …

Predictive Performance Of Newborn Small For Gestational Age By A Us Intrauterine Versus Birth Weight-Derived Standard For Short-Term Neonatal Morbidity And Mortality, Nathan R Blue, Lisa Mele, William A Grobman, Jennifer L Bailit, Ronald J Wapner, John M Thorp, Steve N Caritis, Mona Prasad, Alan T N Tita, George R Saade, Dwight J Rouse, Sean C Blackwell, Eunice Kennedy Shriver National Institute Of Child Health And Human Development Maternal-Fetal Medicine Units (Mfmu) Network

Faculty, Staff and Student Publications

Objective:

The use of birth weight standards to define small for gestational age (SGA) may fail to identify neonates affected by poor fetal growth since they include births associated with sub-optimal fetal growth. Our objective was to compare intrauterine versus birth weight-derived standards to define newborn SGA to predict neonatal morbidity and mortality.

Study Design:

This was a secondary analysis of a multi-center observational study of 118,422 births. Liveborn singleton, non-anomalous newborns born at 23–41 weeks were included. Those with missing gestational age estimation or without a 1^st or 2^nd trimester ultrasound to confirm dating, birth weight, or …

Caregiver-Child Conversations About Sex In African American Women, Hannah King

Electronic Theses and Dissertations

Using grounded theory methods, this study examines the experience of African American women during their caregiver-child conversations about sex and the impacts of the conversations on their sexual attitudes. The process of these conversations begins with an unplanned topic and progresses further to identify six essential themes of these conversations: gender differences, race and religion, protective/emphasis on protection, lack of knowledge, withholding knowledge, and sex negativity/shame. African American women’s description of the process included feelings of shame and negativity towards their sexuality. Caregivers promoted positive messages about sex by having open conversations that advocated for equality between the genders, empower …

Characterization Of Folic Acid, 5-Methyltetrahydrofolate And Synthetic Folinic Acid In The High-Affinity Folate Transporters: Impact On Pregnancy And Development, Ana M. Palacios, Rachel A. Feiner, Robert M. Cabrera

Health Policy & Community Health: Faculty Publications

Objectives:

Folates are B vitamins that are essential for several molecular, cellular, and biological processes, including nucleotide synthesis, methylation, and methionine cycling. The physiological impacts of these processes on health also extend to cell proliferation, folate deficiency anemia, and reduction of the risk of birth defects during pregnancy. The primary objective of this study was to characterize the binding affinities of different folate forms, folic acid (FA), 5-methyltetrahydrofolate (5MTHF), and folinic acid, to the folate receptors α and β, and to the bovine milk folate binding protein. These three dietary forms of folate are found in enriched grains (FA), various …

Assessment Of Oral Human Papillomavirus In Pediatric And Adult Patients Within A Multi-Ethnic Clinic Population, Melissa Kornhaber

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Human papillomavirus (HPV) encompasses a large family of oncogenic viruses responsible for increasing rates of both cervical and oral cancer, particularly among minority and low-income populations. Although this represents an increasingly significant public health risk, few studies have screened for oral HPV within Nevada. Based upon this information, the primary objective of this study was to provide a temporal analysis of oral HPV screening among a primarily low-income, minority patient population.

Methods: This retrospective analysis was reviewed and approved by the Institutional Review Board (IRB). In brief, unstimulated saliva samples were previously obtained from clinical patient volunteers that provided …

The Theory Of Mattering: Implications For Adolescent Depression And Suicidal Ideation, Josie Lucretia Bryan

Boise State University Theses and Dissertations

Recent studies have suggested that mattering may influence both self-esteem and depression, and the perception of not mattering can lead to suicide ideation, attempts, or completion. When young people perceive they matter to those in their social environment, that sense of mattering can act as a protective factor. Existing research supports the notion that mattering is salient to adolescent development and, importantly, potentially malleable which could make it a prevention/intervention factor. The current study endeavored to identify contributing factors to adolescent perceived mattering and to test the Theory of Mattering in an adolescent population when predicting mental health outcomes. A …

An Exploratory Study On Institutional Belonging And Its Effects On Mental Health Outcomes And Academic Success, William Cooney

Boise State University Theses and Dissertations

BACKGROUND

Belonging in higher education is a growing field of research, however there is limited available literature. Institutional belonging encompasses many factors of the college campus environment such as social relationships, extra-curricular activities, academics, institutional support and how they affect a college student’s sense of belonging (Hausmann et al., 2007). The purpose of this exploratory study is to further understand institutional belonging and its relationships with mental health and academic success.

METHODS

This study utilized data from the ACHA-NCHA III, Spring 2020 survey that was randomly given to undergraduate and graduate students (N=5,000) attending a Northwest regional state university. The …

Assessing The Potential Effectiveness Of Diffuse Reflectance Spectroscopy For Quantifying Neonatal Skin Properties Using Tissue Phantoms, Jack Murphy

Biomedical Engineering Undergraduate Honors Theses

Diffuse reflectance spectroscopy (DRS) has previously been shown to be effective at analyzing the optical characteristics of a wide variety of biological tissues, including the skin. In addition to being sensitive to the amount of blood and its oxygenation, DRS can be used to extract bilirubin levels and assess jaundice, a common complication in newborn infants. To assess its potential for being utilized in applications involving neonatal skin, we evaluated the utility of DRS for extracting hemoglobin and bilirubin concentrations from tissue phantoms. Phantom sets were created by including a known amount of scattering and by varying known concentrations of …

Monkeypox Virus Hosts And Transmission Routes: A Systematic Review Of A Zoonotic Pathogen, Mary Walker

Biological Sciences Undergraduate Honors Theses

Monkeypox virus (MPXV) is an etiological agent of Monkeypox with origins believed to be of Central/West Africa. As a member of the orthopoxvirus family and due to its increasing emergence, it has become a pathogen in need of research. This paper works to find common trends of transmission routes and reservoir hosts in previous publications through a systematic review. Articles found on Web of Science containing the search term “Monkeypox” were sorted based on relevance to the review topics of potential reservoir hosts and transmission routes of Monkeypox virus. Through Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), 1,036 …

Respiratory Syncytial Virus (Rsv) Laboratory Surveillance And Mortality In Nebraska, 2016 – 2021, Derek Bumgardner

Capstone Experience: Master of Public Health

Respiratory syncytial virus (RSV) is a common respiratory virus affecting children and adults. The United States RSV peak season occurs regularly between October to May, but in April 2021, an unexpected United States interseason RSV epidemic ensued. RSV laboratory testing has changed in the United States due to increased use of nucleic acid amplification testing (NAAT) rather than antigen-based testing, affecting how RSV seasonal epidemics are determined. Nebraska linked RSV laboratory and death certificate data (2016-2021) were used to calculate crude, specific and adjusted RSV case and mortality rates by age, sex, race, and ethnicity. A Cochran – Armitage test …

Assessing Meat Processing Workers’ Attitudes And Concerns Regarding Covid-19 Vaccination, Karen Schmeits

Capstone Experience: Master of Public Health

The COVID-19 pandemic has impacted industries across the globe. Specifically, for meat processing (meatpacking) facilities, the pandemic has changed the way facilities operate, how the workers perform tasks, and how workers perceive their health. The development of an FDA approved COVID-19 vaccine brought hope to meat processing employers and workers. However, little research has been conducted to know how meat processing workers feel about vaccines generally and how they perceive the COVID-19 vaccine. The purpose of this cross-sectional study was to investigate preventive vaccine determinants and attitudes and concerns specifically regarding the COVID-19 vaccine. Surveys were conducted with 128 meat …

The Perception Of Technology On Continuous Health And Environmental Monitoring For Professional Drivers, Troy Suwondo

Capstone Experience: Master of Public Health

Due to the sedentary nature of professional truck driving (among other high-risk behaviors and hazardous exposures) many suffer from acute and chronic health conditions. There are many potential hazards in the professional driving profession. Many of these hazards come from those that transport hazardous materials. Figuring out what health and environmental indicators are important to measure can be a way to minimize hazards. Continuous health monitoring technology may be an option to detect disease and alert professional drivers when vital signs indicate impending health crises. Before this can be implemented, it will be important to evaluate the perception of wearable …

Effect Of Climate Variability On Lyme Disease Cases In The United States – A Retrospective Study, Larissa Mark

Capstone Experience: Master of Public Health

Vector-borne illnesses are a growing serious global public health threat. According to the CDC, Lyme disease (LD) is the most common vector-borne disease in the United States. It is caused by the bacterium Borrelia burgdorferi and is transmitted to humans through the bite of an infected black-legged tick. Since the discovery, LD has increased in both incidence and geographical distribution. Vector life cycles and disease transmission are highly sensitive to abiotic conditions; as such, it is expected that climate change will alter the geographic distribution and magnitude of vector-borne illnesses. Certain facets of climate change like precipitation patterns, greater climate …

Tocilizumab In Patients Hospitalised With Covid-19 Pneumonia: Efficacy, Safety, Viral Clearance, And Antibody Response From A Randomised Controlled Trial (Covacta), Ivan O Rosas, Norbert Bräu, Michael Waters, Ronaldo C Go, Atul Malhotra, Bradley D Hunter, Sanjay Bhagani, Daniel Skiest, Sinisa Savic, Ivor S Douglas, Julia Garcia-Diaz, Mariam S Aziz, Nichola Cooper, Taryn Youngstein, Lorenzo Del Sorbo, David J De La Zerda, Andrew Ustianowski, Antonio Cubillo Gracian, Kevin G Blyth, Jordi Carratalà, Bruno François, Thomas Benfield, Derrick Haslem, Paolo Bonfanti, Cor H Van Der Leest, Nidhi Rohatgi, Lothar Wiese, Charles Edouard Luyt, Rebecca N Bauer, Fang Cai, Ivan T Lee, Balpreet Matharu, Louis Metcalf, Steffen Wildum, Emily Graham, Larry Tsai, Min Bao

Faculty, Staff and Students Publications

BACKGROUND: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab did not improve 28-day mortality, but shortened hospital and intensive care unit stay. Longer-term effects of tocilizumab in patients with COVID-19 are unknown. Therefore, the efficacy and safety of tocilizumab in COVID-19 beyond day 28 and its impact on Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) clearance and antibody response in COVACTA were investigated.

METHODS: Adults in Europe and North America hospitalised with COVID-19 (

FINDINGS: By day 60, 24·5% (72/294) of patients in the tocilizumab arm and 25·0% (36/144) in the placebo arm died (weighted …

Novel And Extendable Genotyping System For Human Respiratory Syncytial Virus Based On Whole-Genome Sequence Analysis, Jiani Chen, Xueting Qiu, Vasanthi Avadhanula, Samuel S Shepard, Do-Kyun Kim, James Hixson, Pedro A Piedra, Justin Bahl

Faculty, Staff and Student Publications

BACKGROUND: Human respiratory syncytial virus (RSV) is one of the leading causes of respiratory infections, especially in infants and young children. Previous RSV sequencing studies have primarily focused on partial sequencing of G gene (200-300 nucleotides) for genotype characterization or diagnostics. However, the genotype assignment with G gene has not recapitulated the phylogenetic signal of other genes, and there is no consensus on RSV genotype definition.

METHODS: We conducted maximum likelihood phylogenetic analysis with 10 RSV individual genes and whole-genome sequence (WGS) that are published in GenBank. RSV genotypes were determined by using phylogenetic analysis and pair-wise node distances.

RESULTS: …

A D2 To D1 Shift In Dopaminergic Inputs To Midbrain 5-Ht Neurons Causes Anorexia In Mice, Xing Cai, Hailan Liu, Bing Feng, Meng Yu, Yang He, Hesong Liu, Chen Liang, Yongjie Yang, Longlong Tu, Nan Zhang, Lina Wang, Na Yin, Junying Han, Zili Yan, Chunmei Wang, Pingwen Xu, Qi Wu, Qingchun Tong, Yanlin He, Yong Xu

Faculty, Staff and Students Publications

Midbrain dopamine (DA) and serotonin (5-HT) neurons regulate motivated behaviors, including feeding, but less is known about how these circuits may interact. In this study, we found that DA neurons in the mouse ventral tegmental area bidirectionally regulate the activity of 5-HT neurons in the dorsal raphe nucleus (DRN), with weaker stimulation causing DRD2-dependent inhibition and overeating, while stronger stimulation causing DRD1-dependent activation and anorexia. Furthermore, in the activity-based anorexia (ABA) paradigm, which is a mouse model mimicking some clinical features of human anorexia nervosa (AN), we observed a DRD2 to DRD1 shift of DA neurotransmission on 5-HT

Examining The Effects Of Oral Contraceptive Use On Thermoregulation, Whitley C. Atkins

Graduate Theses and Dissertations

Purpose: The purpose of this investigation was to evaluate the effects of combined (estradiol and progestin) monophasic oral contraceptive pill (OCP) use on thermoregulation. Further, we sought to evaluate OCP use on acute rehydration post-exercise in the heat using recommended rehydration guidelines. Methods: Twelve healthy, aerobically trained (VO2peak = 47.8 ± 4.7 mL/kg/min), long term female oral contraceptive users completed a familiarization trial and two experimental days separated by ≥ 7 days. The two experimental trials were identical except for the hormone dosing phase. One trial was completed during the third week of active pill dosing (ACT) and one during …

What Is The Prevalence Of Dirofilaria Immitis (Dog Heartworm) In Invasive Aedes Mosquitoes?, Leen Yousef, Johan Espinoza Corrales, Daniela H. Dolar, Taylor K. Trieu, Aisha Popalzai, Agamchat Dhami

Pacific Undergraduate Research and Creativity Conference (PURCC)

No abstract provided.

Investigating The Links Between Body Composition And Female University Students’ Night Eating Habits And Sleep Quality, Hanisah Rosli, Arimi Fitri Mat Ludin, Amanda Priscilla Lim, Vimalah Vallavan, Lew Sze Yuen, Norizatul Hidayah Yusop, Nur Athirah Razali, Amerull Daneal Amran, Nurfarahin Asmadi, Mohd Sham Othman

Makara Journal of Health Research

Background: Malaysia has the highest prevalence of obesity among Southeast Asian countries, and the current number is expected to increase further. In particular, the rate of obesity is reportedly increasing among females and young adults in Malaysia. Modern lifestyle habits, which include night eating and poor sleep quality, have been shown to increase the risk of obesity and high body fat. This study aims to determine the link between female university students’ body composition and their night eating habits and sleep quality.

Methods: Body composition was measured using a Bioelectrical Impedance Analysis (BIA) analyzer. Night eating syndrome and …