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Association Between Oral Health Behavior,Oral Hygiene Status, And Oral Health Status Among Primary School Children In Bangkok, Thailand : A Latent Class Analysis, Pemmika Intato Jan 2023

Association Between Oral Health Behavior,Oral Hygiene Status, And Oral Health Status Among Primary School Children In Bangkok, Thailand : A Latent Class Analysis, Pemmika Intato

Chulalongkorn University Theses and Dissertations (Chula ETD)

Oral health affects both the overall health and quality of life of children. Dental caries and gingivitis are one of the most common global oral health problems among school children, including those in Thailand. Both problems are diet- and behavioral-related diseases, with various risk factors contribute to dental caries and gingivitis. This study aims to classify the clusters of oral health status among primary school children in Bangkok, Thailand, and identify association between the identified classes, oral health behavior, and oral hygiene status. The study utilized secondary data from dental chart records in the School Oral Health Promotion Program, Department …


Blended Program And Its Impact On Knowledge, Attitude And Help-Seeking Intention Of Conflict-Related Sexual Violence Among Internally Displaced People In Northern Myanmar Camps: A Quasi-Experimental Study, Chit Pyae Pyae Han Jan 2023

Blended Program And Its Impact On Knowledge, Attitude And Help-Seeking Intention Of Conflict-Related Sexual Violence Among Internally Displaced People In Northern Myanmar Camps: A Quasi-Experimental Study, Chit Pyae Pyae Han

Chulalongkorn University Theses and Dissertations (Chula ETD)

Introduction As a result of several military coups and internal armed conflicts, Myanmar has the longest history of civilian wars in the world. Human rights violations, gender-based violence, and sexual violence have become more widespread as a result of extensive conflicts and humanitarian crises. The United Nations is concerned about the detrimental consequences of sexual violence in military situations. A community-based program designed to prevent sexual violence is crucial in mitigating risk factors and enhancing protective factors Methods The two-group quasi-experimental study evaluated the impact of a community-based program to prevent sexual violence and examined the experiences of survivors among …


Knowledge Attitude And Practice Of Who Mental Health Guidelines For Non-Specialist Primary Healthcare Providers In Wuhua District, Kunming, People's Republic Of China: A Cross-Sectional Study, Liesha Luohe Jan 2023

Knowledge Attitude And Practice Of Who Mental Health Guidelines For Non-Specialist Primary Healthcare Providers In Wuhua District, Kunming, People's Republic Of China: A Cross-Sectional Study, Liesha Luohe

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: The 'Healthy China 2030' policy emphasizes the importance of mental healthcare at the primary healthcare level. Globally, primary healthcare(PHC) service delivery is considered the most effective approach for managing mental health (MH) disorders. The WHO’s mental health gap intervention guide version 2 (mhGAP-IG.v2), is a decision support tool for non-specialists for the assessment, management, and follow-up of mental, neurological, and substance use disorders. However, no studies have assessed primary healthcare providers’ (HCPs) knowledge, attitudes, and practices on MH services in the western part of China. Objectives: To determine the PHC providers’ characteristics and MH service provision level in Wuhua …


Association Between Greenness And Environmental Parameters Exposure And Depression Among Residents In Bangkok, Thailand: An Ecological Longitudinal Study, Wilaipak Nilsalai Jan 2023

Association Between Greenness And Environmental Parameters Exposure And Depression Among Residents In Bangkok, Thailand: An Ecological Longitudinal Study, Wilaipak Nilsalai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Depression and mental health issues are on the rise, and it is hypothesized that environmental factors may play a role in the development of these diseases. Greenness is one of the potential factors, and this study aims to investigate the relationship between living in greener areas and depression incidence in Bangkok. This is an ecological longitudinal study using secondary data documented between 2018 and 2020, utilizing data on depression (ICD-10 F32, F33), environmental parameters (PM2.5 (µg/m3), temperature (ºC), relative humidity (RH; %), and demographic variables (population density, number of communities, number of hospitals, number of healthcare centers, and divorce rate) …


Perception Of Academic Stress And Family Relationship On Mental Well-Being Among Pharmacy Students At Chulalongkorn University In Thailand: A Cross-Sectional Survey Study, Chompunoot Prasongpol Jan 2023

Perception Of Academic Stress And Family Relationship On Mental Well-Being Among Pharmacy Students At Chulalongkorn University In Thailand: A Cross-Sectional Survey Study, Chompunoot Prasongpol

Chulalongkorn University Theses and Dissertations (Chula ETD)

University students' mental health and well-being have gained more global attention due to their increasing influence on health and societal issues. The cross-sectional study, conducted in May 2024 among undergraduate Chulalongkorn University pharmacy students in Thailand, aims to investigate the proportion of mental well-being levels and determine the relationship between general characteristics, perceptions of academic stress, and family relationships toward mental well-being levels among pharmacy students at Chulalongkorn University. The study used an online, self-administered questionnaire. Descriptive statistics, simple logistic regression, and multiple logistic regression models were employed for data analysis. Out of 289 pharmacy students, 199 were predominantly female …


Associated Factors With Suicide Mortality In Thailand:A Mediating Roles Of Urban And Rural Areas, Kajohnsak Tangkwampien Jan 2023

Associated Factors With Suicide Mortality In Thailand:A Mediating Roles Of Urban And Rural Areas, Kajohnsak Tangkwampien

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: Suicide is a global public health problem that affects individuals, families, and communities. The World Health Organization (WHO) estimates that more than 700,000 people die by suicide worldwide each year. Despite the significance of this issue, important factors like rural and urban settings, which have different definitions in each country and result in specific contextual effects on suicide, are overlooked. Objectives: To understand the role of living in urban and rural as mediator on the associated factors (socio-demographic factors, mental and physical problems, effect from COVID-19, economic factors, relationship problems, history of self-harm, and warning signs, method of suicide) …


Ultrasound-Assisted Extraction Of Cannabis Sativa And Biological Activities Assessments For Dermatological Application, Pannita Kongtananeti Jan 2023

Ultrasound-Assisted Extraction Of Cannabis Sativa And Biological Activities Assessments For Dermatological Application, Pannita Kongtananeti

Chulalongkorn University Theses and Dissertations (Chula ETD)

Cannabis sativa L. is a medicinal plant that has long been used in Thai traditional medicine and is still widely used today, with many uses in pharmaceuticals, including the treatment of skin infections. It contains a complex mixture of secondary metabolites, including cannabinoids and non-cannabinoid-type constituents, especially detla-9-tetrahydrocannabinol (THC), cannabidiol (CBD), and terpenes. However, fewer studies of cannabis have been reported regarding its anti-aging potential by investigating tyrosinase inhibition activity. In this study, ultrasound-assisted extraction (UAE) of 5 different parts of Cannabis sativa L., the determination of bioactive compounds using GC–MS/MS and the assessment of their biological properties related to …


Effects Of A Therapeutic Lifestyle Modification Intervention On Cardio-Metabolic Health, Sexual Functioning, And Health-Related Quality Of Life In Perimenopausal Chinese Women: A Randomized Controlled Trial, Yuru Wang Jan 2023

Effects Of A Therapeutic Lifestyle Modification Intervention On Cardio-Metabolic Health, Sexual Functioning, And Health-Related Quality Of Life In Perimenopausal Chinese Women: A Randomized Controlled Trial, Yuru Wang

Chulalongkorn University Theses and Dissertations (Chula ETD)

Objectives: Our study aimed to explore the effects of a therapeutic lifestyle modification (TLM) intervention on cardiometabolic health, sexual functioning, and health-related quality of life in perimenopausal Chinese women. Methods: This was a 12-week, two-parallel arm, randomized controlled trial conducted in the First Affiliated Hospital of Yunnan University of Chinese Medicine, Kunming City, China. Ninety-four eligible perimenopausal women aged between 40 and 55 years were randomly assigned to either a TLM intervention or usual care at a 1:1 ratio. Menopause-specific quality of life (MENQOL), female sexual function index (FSFI), pelvic floor muscle strength (PFMS), and composite cardiometabolic biomarkers were evaluated …


Implementing A Mobile Saliva Rinse Screening For P16 Markers For Hpv (Human Papillomavirus) Positive Head And Neck Cancers In Central Kentucky, Madeline Brown Jan 2023

Implementing A Mobile Saliva Rinse Screening For P16 Markers For Hpv (Human Papillomavirus) Positive Head And Neck Cancers In Central Kentucky, Madeline Brown

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Rates of HPV-related head and neck cancers are increasing across the nation and more specifically, there has been a significant increase in the state of Kentucky. This study focuses on the implementation of a mobile clinic saliva-rinse screening program. This program will be set up at UK Athletics Men's basketball and football games in hopes of recruiting middle aged men ages 45-60, who are the target audience of the study. This is the population with highest prevalence for HPV positive head and neck cancers and also the population least likely to visit their health providers regularly. A quick saliva rinse …


Changes In Severity Of Diabetes At Diagnosis Following The Onset Of The Sars-Cov-2 Pandemic, Annelise King Jan 2023

Changes In Severity Of Diabetes At Diagnosis Following The Onset Of The Sars-Cov-2 Pandemic, Annelise King

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

During the SARS-CoV-2 pandemic it was seen that diabetes was a risk factor for severe COVID-19. The objective of this study is to assess the severity of diabetes at diagnosis during the COVID-19 pandemic compared to pre-pandemic to see how the pandemic and SARS-CoV-2 infection impacted the severity of diabetes. This study used University of Kentucky electronic health records of 13,794 patients who developed diabetes. The majority of patients were female, white non-Hispanic, 65+, and living in an urban area. There were differences seen between the COVID-19 positive and negative cohorts in the DKA and HbA1c variables, with …


Effect Of Medicaid Expansion On Inflammatory Bowel Disease And Healthcare Utilization, Brittany Levy Jan 2023

Effect Of Medicaid Expansion On Inflammatory Bowel Disease And Healthcare Utilization, Brittany Levy

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Inflammatory bowel disease (IBD) affects over 3 million adults in America, relaying a

need for chronic disease management. Along with 24 other states, Kentucky expanded the

Medicaid program January 1, 2014. We hypothesize, Medicaid expansion adoption results in

reduced emergency healthcare services, and increased elective healthcare services with a

reduction in overall healthcare utilization by individuals in the adult IBD population.

The Hospital Inpatient Discharge and Outpatient Services Database identify encounters

related to ulcerative colitis or Crohn’s disease from 2009-2020, in Kentucky. Patient

demographics, admission type, discharge, length of stay, and hospital charges were compared.

3386 pre-expansion and 24255 post …


Retrospective Analysis Of Non-Ketotic Hyperglycinemia Patients In Central And Eastern Kentucky, Shane Reeves Jan 2023

Retrospective Analysis Of Non-Ketotic Hyperglycinemia Patients In Central And Eastern Kentucky, Shane Reeves

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Aim: To obtain a better understanding of the non-ketotic hyperglycinemia (NKH) patient population in regards to clinical features, mortality, geographic clustering, genetics, and incidence rate within the University of Kentucky (UK) catchment area of Central and Eastern Kentucky.

Methods: Patients with ICD codes corresponding to NKH who were treated at UK between January 1, 2008, and July 1, 2022, and who had clinical documentation available for review were identified through UK’s medical records (N=15). Demographic and clinical data were obtained through review of these patient’s charts in the electronic medical record. Differences in features among patients was assessed utilizing Fisher …


Blue Oval Sk Battery Park Environmental Impact And Community Guide, Warren Rummage Jan 2023

Blue Oval Sk Battery Park Environmental Impact And Community Guide, Warren Rummage

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

This Capstone Project Paper will discuss the potential effects of the BlueOval SK Battery Park being constructed in Glendale, Kentucky based on knowledge attained from open records requests and available publicly online. Based on the process of attaining said information, a Community Guide has been generated and is available to distribute to concerned community members. It is the hope that this work will enable those in Hardin County, and possibly beyond, to ensure their environment and community health are prioritized during the construction phase and eventual operation of the EV-battery manufacturing faciliities on this massive 1,500 acre plot of land.


Community Pharmacy Provision Of Extended-Release Injectable Naltrexone In Kentucky: Perspective Of People Who Use Opioids, Anye Wamucho Jan 2023

Community Pharmacy Provision Of Extended-Release Injectable Naltrexone In Kentucky: Perspective Of People Who Use Opioids, Anye Wamucho

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Aim: To identify demographic, socio-economic, and other factors associated with likelihood of obtaining extended-release injectable naltrexone (EIN) if provided in a private space at a local pharmacy among people who use opioids (PWUO) in rural Appalachian Kentucky.

Methods: People who used opioids in the past 6 months in rural Appalachian Kentucky (n=170) completed interviewer-administered questionnaires eliciting demographic, socio-economic, and other characteristics. Participants were also asked about whether they will be more likely to obtain EIN if provided in a private space at a local pharmacy. Factors associated with increased likelihood to obtain pharmacy-provided EIN were assessed using unadjusted univariate and …


Effect Of Positive Emotion Intervention During Late Pregnancy On Improving Colostrum Secretion: A Randomised Control Trial Protocol, Kechen Xu, Ying Xie, Xiujun Han, Ying Yu, Suqing Liu, Suliu Wu, Qian Yang, Qi Zhang Jan 2023

Effect Of Positive Emotion Intervention During Late Pregnancy On Improving Colostrum Secretion: A Randomised Control Trial Protocol, Kechen Xu, Ying Xie, Xiujun Han, Ying Yu, Suqing Liu, Suliu Wu, Qian Yang, Qi Zhang

Community & Environmental Health Faculty Publications

Introduction Though evidence has revealed the beneficial effects of cognitive improvement interventions on breastfeeding, the effect of psychological interventions has rarely been studied. This study aims to test whether promoting a positive emotion intervention, 'Three Good Things' intervention, during the last trimester of pregnancy can enhance early colostrum secretion and breastfeeding behaviours by modulating the hormones associated with lactation (prolactin and insulin-like growth factor I). We will attempt to promote exclusive breastfeeding by using physiological behavioural measures.

Methods and analysis This study is designed as a randomised controlled trial conducted in the Women's Hospital School of Medicine at Zhejiang University …


An Analysis Of Water Quality At Orange County, California Beaches, Naomi Meurice Jan 2023

An Analysis Of Water Quality At Orange County, California Beaches, Naomi Meurice

Pomona Senior Theses

Beaches in Southern California are highly recreated by residents and visitors, making beaches socially and economically important. Public health departments in coastal communities are in charge of measuring water quality and ensuring it is safe for users. Research in the past has indicated that beach water quality gets worse after storms, with bacteria levels jumping on the day of a storm and staying high for up to five days. Studies have shown these spikes in bacteria to be associated with storm runoff, with beaches closer to runoff discharge locations experiencing more impact. However, prior research has not considered the period …


Integrating Feminist Approaches In Counseling Work With Adult Women, Kristen M. Toole Jan 2023

Integrating Feminist Approaches In Counseling Work With Adult Women, Kristen M. Toole

Adultspan Journal

The scope of ‘women’s issues’ in counseling is an ever-evolving landscape. Recent events such as the reversal of Roe v. Wade and the disproportionate impact of COVID-19 on women serve as powerful reminders of the necessity of this focus while underscoring a deep-rooted history of oppressive patriarchal structures. Therefore, counselors must remain informed of the unique considerations surrounding adult women in counseling and acquire proficiency in versatile techniques to meet this population’s nuanced needs. This article examines the complexity of contemporary womanhood and explores the fundamentals of Feminist Counseling Theory (FCT), a holistic, multiculturally conscious, social justice theory in counseling. …


A Systematic Review To Study The Global Patterns And Policies Of Hiv Harm Reduction Programs And Their Impact Among People Who Inject Drugs, Noura Shaltout, Rania Soliman, Lamia Refaey, Rim Ghazal, Mirna Atteya, Nahla Elmedany Jan 2023

A Systematic Review To Study The Global Patterns And Policies Of Hiv Harm Reduction Programs And Their Impact Among People Who Inject Drugs, Noura Shaltout, Rania Soliman, Lamia Refaey, Rim Ghazal, Mirna Atteya, Nahla Elmedany

Papers, Posters, and Presentations

Aim: This study aims to provide an updated estimate of HIV prevalence among people who inject drugs (PWID) globally, as well as investigate different policies and methods for applying harm reduction. This article focuses on the two major and the most frequently used harm reduction techniques, Syringe-Service Programs (SSPs) and Opioid Agonist Therapy (OAT). Methods: A comprehensive systematic review was undertaken across multiple international databases during the period of (August-December 2021). For studies conducted before 2005, we used data from a previous published systematic review. Thirty-six studies were included, including studies that had performed HIV testing and had a confirmed …


Health Behavior And Outlooks In An Altered Microbial Diversity: Changes In Parental Attitudes On ‘Building Immunity’ Throughout The Covid-19 Pandemic, Jennifer Vidal Jan 2023

Health Behavior And Outlooks In An Altered Microbial Diversity: Changes In Parental Attitudes On ‘Building Immunity’ Throughout The Covid-19 Pandemic, Jennifer Vidal

Pitzer Senior Theses

The Covid-19 Pandemic in a short amount of time put into action disease control measures. Current literature has sought to address the long-term effects of sanitization efforts and social isolation on the diversity of the microbiome and the future of infectious diseases. Microbes – microorganisms such as bacteria, protozoa, algae, fungi, and viruses – inhabit the natural environment and human microbiome with our immune system, playing an essential role in immune regulation. The interplay between humans and microbes forms early immune development that has impacted parents’ attitudes toward microbes shown through their participation in Covid-19 preventative health practices. Using the …


Using Wastewater-Based Epidemiology To Study Chlamydia Occurrence On A College Campus, Jessie E. Chin Quee Jan 2023

Using Wastewater-Based Epidemiology To Study Chlamydia Occurrence On A College Campus, Jessie E. Chin Quee

Honors Undergraduate Theses

Chlamydia is a sexually transmitted disease caused by Chlamydia trachomatis, commonly affecting sexually active college-aged adults. Presently, opportunistic testing, self-testing, and information campaigns are methods to screen vulnerable populations and raise awareness about chlamydia. Chlamydia remains underdiagnosed and undertested due to a lack of participation by individuals who may have been exposed to it. Wastewater-based epidemiology is a rising biomonitoring tool that detects the presence of disease- and drug-specific biomarkers in a community's wastewater. In this study, wastewater-based epidemiology was used to detect the presence of C. trachomatis on the University of Central Florida campus. Wastewater samples were collected …


Neurodivergent Transgender And Gender Diverse Youth And Young Adults’ Experiences Of Dual Minority Status In Healthcare Settings In Connecticut, Mac Reutter Jan 2023

Neurodivergent Transgender And Gender Diverse Youth And Young Adults’ Experiences Of Dual Minority Status In Healthcare Settings In Connecticut, Mac Reutter

Public Health Theses

Introduction The co-occurrence of gender diversity and neurodiversity has received increased attention in recent years. Clinical statistics suggest that transgender and gender diverse (TGD) individuals are more likely to be diagnosed with autism spectrum disorder than their cisgender counterparts, and that transgender and gender diverse neurodivergent (TGD-ND) individuals, particularly autistic individuals or those with ADHD, are at elevated risk of poor mental health outcomes compared to their neurotypical or cisgender counterparts. Thus, the TGD-ND population is both a notable proportion of the TGD population and a contingent of the population facing significant health disparities. A minority stress model is useful …


Qualitative Analysis Of Anti-Abortion Discourse Used In Arguments For A 6-Week Abortion Ban In South Carolina, Victoria C. Lambert, Emily E. Hackworth, Deborah Lynn Billings Phd Jan 2023

Qualitative Analysis Of Anti-Abortion Discourse Used In Arguments For A 6-Week Abortion Ban In South Carolina, Victoria C. Lambert, Emily E. Hackworth, Deborah Lynn Billings Phd

Publications

Background: On June 24, 2022, The U.S. Supreme Court overturned Roe v. Wade, leaving abortion legislation entirely up to states. However, anti-abortion activists and legislators have organized for decades to prevent abortion access through restrictive state-level legislation. In 2019, South Carolina legislators proposed a bill criminalizing abortion after 6 weeks gestation, before most people know they are pregnant. The current study examines the anti-abortion rhetoric used in legislative hearings for this extreme abortion restriction in South Carolina. By examining the arguments used by anti-abortion proponents, we aim to expose their misalignment with public opinion on abortion and demonstrate that their …


An Association Of The Transgenerational Implications Of Redlining And Obesity On Pediatric Type Ii Diabetes, Carlin Dexter Nelson Jan 2023

An Association Of The Transgenerational Implications Of Redlining And Obesity On Pediatric Type Ii Diabetes, Carlin Dexter Nelson

Walden Dissertations and Doctoral Studies

s the prevalence and incidence of childhood obesity has increased, so has the number of cases of pediatric Type 2 diabetes mellitus (T2DM). Although made unconstitutional in 1968, the transgenerational implications of redlining can be observed in disinvestments resulting in neighborhood detraction. Utilizing the 2019–2020 National Children’s Health Survey, the purpose of the study was to evaluate the relationship between obesity, T2DM, and neighborhood detraction elements as well as assessed indicators of T2DM in non-institutionalized children 6 through17 years of age (N = 34,725). The social determinants of health perspective served as the conceptual framework for the study. Results indicated …


Nutrient Pollution And Chlorophyll-A As A Precursor To Harmful Algal Blooms And Cyanotoxins In Rehabilitated Machado Lake, California, Michael E. Shiang Jan 2023

Nutrient Pollution And Chlorophyll-A As A Precursor To Harmful Algal Blooms And Cyanotoxins In Rehabilitated Machado Lake, California, Michael E. Shiang

Walden Dissertations and Doctoral Studies

Algal blooms result in the formation of cyanotoxic conditions in a freshwater lake causing severe detrimental impacts to community and public health. Nitrogen, phosphorous, and ammonia stimulate the growth of phytoplankton biomass and algae, as measured by chlorophyll. This retrospective quantitative research study, grounded in the socioecological model, examined the relationship between nutrient pollutants and chlorophyll-a (Chl-a) that forecast harmful algal blooms, a precursor to cyanotoxins. A former impaired lake, Machado Lake in California, provided an ideal setting to assess relationships among nutrient indicators and Chl-a post-lake rehabilitation. Correlation and multiple regression analyses were performed to determine if a relationship …


Association Between Antidepressant Adherence And Major Depressive Disorder Complications, Philip Lisinge Jan 2023

Association Between Antidepressant Adherence And Major Depressive Disorder Complications, Philip Lisinge

Walden Dissertations and Doctoral Studies

Despite evidence that antidepressants are more effective at treating major depressive disorder (MDD) symptoms, there is growing evidence that MDD management is still hampered by nonadherence to antidepressant treatment regimens. Researchers have suggested that MDD, if untreated, might lead to MDD-related complications, but other researchers have argued that adherence to antidepressants can lead to these same MDD-related complications. This quantitative cross-sectional study used primary data collected from 298 volunteers to examine the association between MDD-related complications and antidepressant adherence to clarify these diverging opinions. The study’s objective was to provide evidence to accept or reject the premise that antidepressant adherence …


Traditional Healing And Biomedicine Use In Urban American Indians Living With Diabetes, Elin Elise Kambuga Jan 2023

Traditional Healing And Biomedicine Use In Urban American Indians Living With Diabetes, Elin Elise Kambuga

Walden Dissertations and Doctoral Studies

The purpose of this interpretative qualitative study was to describe influences that affect the use of traditional healing and biomedical health services for type 2 diabetes to help health educators develop more culturally competent diabetes education programs for urban American Indian/Alaska Native (AI/AN) communities in the United States. The theoretical framework used for this study was the social ecological model (SEM). Using the SEM, the research questions were crafted to explore experiences of participants connected to personal, interpersonal, community, institutional, policy, and educational factors that influenced the use of traditional healing and biomedical health services. Urban AI/AN adults living in …


The Association Between Working Habits And Hypertension Among First Generation African Immigrants, Olalekan Kilo Jan 2023

The Association Between Working Habits And Hypertension Among First Generation African Immigrants, Olalekan Kilo

Walden Dissertations and Doctoral Studies

Even though hypertension affects people of all races, it is more prevalent among African Americans. However, recent research has revealed that the prevalence of hypertension is progressively increasing across Africa. African immigrants in the United States are the least-studied immigrant group prone to health inequalities when compared to their African American counterparts. To help bridge this gap, a secondary data analysis of a cross-sectional study was conducted to investigate the association between working habits (hours worked, diet at work), length of stay in the United States, and hypertension rates for first-generation African immigrants residing in the United States. The study …


Genetic And Pharmacogenetics Associations Of Cancer Disparities In Appalachia, Nan Lin Jan 2023

Genetic And Pharmacogenetics Associations Of Cancer Disparities In Appalachia, Nan Lin

Theses and Dissertations--Pharmacy

Individuals residing in Appalachian regions have significant health disparities, including higher cancer incidence and mortality rates. Previous studies have addressed the impact of socioeconomic status and environmental risk factors on Appalachia cancer disparities, while few studies have evaluated genetic risk factors.

Germline whole exome sequencing samples from 7,078 individuals with cancer (759 Appalachians) were evaluated. Demographics and relatedness were assessed using KING. Ethnicity was verified by principal component analysis using TRACE, which included 6,034 individuals (85%) of European genetic ancestry. After QC filtering, 5,980 individuals were analyzed. To assess the overall predisposition of hereditary disease, gene level frequency of likely …


Evaluating The Impact Of Mental Health Needs And Services Disruption: Covid-19 & Wisconsin Children’S Welfare Services, Gavin Rienne Jan 2023

Evaluating The Impact Of Mental Health Needs And Services Disruption: Covid-19 & Wisconsin Children’S Welfare Services, Gavin Rienne

Theses and Dissertations--Epidemiology and Biostatistics

Children’s traumatic experiences have lifelong impacts on their mental health and quality of life, therefore mental health services are a critical part of necessary community resources. The increased frequency and severity of natural disasters such as hurricanes, tornadoes, and pandemics reinforces the need to examine and understand the importance of mental health and child services in response to disaster events. This research assesses the relationship between disasters and subsequent health service utilization amongst children and adolescents. We investigated current research on the relationship between children’s mental health and community mental health resource efficacy and accessibility after a major disaster by …


Maternal Occupation And Pediatric Brain Cancer In Kentucky, Mary Elizabeth Begley Jan 2023

Maternal Occupation And Pediatric Brain Cancer In Kentucky, Mary Elizabeth Begley

Theses and Dissertations--Epidemiology and Biostatistics

Pediatric brain cancer is a rare and potentially deadly diagnosis that affects children in Kentucky at a higher incidence than those nationally. Limited exposures in children early in life to warrant the development and progression of brain cancer point to the role parental exposures experienced in the period prior to conception and throughout pregnancy may play in its development. Many of these exposures may be experienced through occupation.

Data on a subset of pediatric brain cancer cases in Kentucky was compared to all cases diagnosed in the state from 1995 to 2019. Survey data of the study sample was collected …