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The Nuclear Contamination Of Kazakhstan, Rebecca Marie Matter

Graduate Program in International Studies Theses & Dissertations

This thesis studies the radioactive contamination of Kazakhstan's environment, concentrating on the period between February 1989 and January 1993. For each type of nuclear degradation in Kazakhstan the thesis asks the questions: what is its cause and extent, what are its consequences for humans, and what are the human responses. The main causes of Kazakhstan's nuclear devastation are atomic weapons' tests, uranium mining, manufacturing of uranium fuel, and the operation of a fast breeder reactor power generator unit. The amount of radioactive contamination is colossal. The consequences for the health of the population, especially at Semey, are severe. The human …

Validation Of A Bag Sampling Method For 1,3-Butadiene, Lori Eckenrode

Community & Environmental Health Theses & Dissertations

At this time there is no NIOSH approved means for bag sampling 1,3-butadiene. An attempt was made to use the application of cold (0°F) to inhibit the reactivity of the gas prior to analysis. The State of California Air Resources Board has an approved method for the gas chromatographic analysis of 1,3-butadiene from stationary sources. The method was utilized in the application of industrial hygiene monitoring of affected workers. The application of cold was found to be ineffective at inhibiting the highly reactive nature of 1,3-butadiene. Analyte losses were too great to classify the method as an accurate measure of …

Analysis And Evaluation Of The Workplace Exposure Assessment Workbook Developed By Keith Tait Including Some Recommended Revisions, Lisa Hebberd

UNLV Theses, Dissertations, Professional Papers, and Capstones

Some risk due to the contamination of workplace environments is an inevitable part of human lives. These risks can often be reduced by improving the control of environmental pollution in the workplace. An extremely important challenge for any industry is to develop a mechanism to identify acceptable levels of safety, or "acceptable risk" in the workplace for specific situations, and to assure adequate quality control over measured or calculated exposure concentrations and their possible contributions to adverse health effects.

Physical Inactivity. Workshop V. Aha Prevention Conference Iii. Behavior Change And Compliance: Keys To Improving Cardiovascular Health, Steven N. Blair, Kenneth E. Powell, Terry L. Bazzarre, James L. Early, Leonard H. Epstein, Lawrence W. Green, Sally S. Harris, William L. Haskell, Abby C. King, Jeffrey Koplan, Bess H. Marcus, Ralph S. Paffenbarger Jr., Kimberly K. Yeager

Faculty Publications

No abstract provided.

Toxics Use Reduction: Pro And Con, Francine Laden, George M. Gray

RISK: Health, Safety & Environment (1990-2002)

With the Massachusetts Toxics Use Reduction Act as an example, important issues related to the goals and effectiveness of TUR are examined. The benefits as claimed by proponents are contrasted with shortcomings outlined by opponents in point-counterpoint style. Ultimately, the authors call for more balanced analysis.

Commencement Program 1993, Loma Linda University

Commencement Programs

CONTENTS

2 | 1993 Events of Commencement

3 | Academic Procession

4 | The Speakers

7 | The Honorees

11 | The Zapara Award

Order of Program

• School of Medicine, 14
• School of Dentistry, 21
• Graduate School, 29
• School of Nursing, 37
• School of Public Health, 41
• School of Allied Health Professions, 48

Aggressive Angiomyxoma Of Vulva, Farrukh Aijaz, Shahid Pervez, Shehnaz Wasti, Sheema H. Hassan

Department of Pathology and Laboratory Medicine

No abstract provided.

Laboratory Health And Safety Compliance Guide For Private Colleges And Universities, Gina Marie Ochs

Theses

Academic laboratories are presented with the unique challenge of ensuring the health and safety of all people involved in daily activities. The Occupational Safety and Health Administration (OSHA) recently enacted the regulation 29 CFR 1910.1450, "Occupational Exposure to Hazardous Chemicals in Laboratories," which applies to all private employers (including colleges and universities). In this work, a guide is developed to assist private colleges and universities comply with applicable governmental regulations and to ensure the health and safety of all individuals involved with laboratory activities.

Academic laboratories warrant special consideration because of the nature of experimentation (variation in research and classroom …

Compliance Documentation For Osha's Bloodborne Pathogen Standard Including Exposure Control Plan And Training, Edward Lloyd Tyerman

Theses

The Occupational Safety and Health Administration's (OSHA) regulation on Bloodborne Pathogens is in full effect since its introduction on December, 1991. This standard mandates that every company whose workers may expect to come into contact with human blood, or other body fluids, during the course of their work develop an Exposure Control Plan, train employees about Bloodborne Pathogens and establish work practice controls. All hospitals, physician and dental offices, ambulance companies, emergency medical technicians, medical laboratories, fire departments, and sites with their own first aid and response teams must comply with the standard.

Bloodborne pathogens include, among others, the human …

Correlates And Infant Mortality: Sudden Infant Death Syndrome Among Black Women In The United States, Paulette Aubrey

Masters Theses

Often referred to as "cot death" or "crib death," sudden infant death syndrome (SIDS) is the single leading cause of infant death in infants aged 28 days to 1 year of life. Although the exact etiology of SIDS remains unknown, epidemiological studies have identified risk factors associated with higher rates of SIDS. In this study, the relationship between sudden infant death syndrome and maternal education among black women who gave birth in the United States during 1983 was examined.

The population for this study consisted of black infants who were born in 1983 and died before their first birthday. Among …

A Multiple Case Study Of Selected Individuals Who Facilitate The Successful Adoption Of Environmental Public Policy, John H. Austin

Health Services Research Dissertations

The purpose of this study was to determine the personal and professional characteristics of successful individuals who have had a positive influence on the development of public policy concerning the environment. Additionally, which characteristics are most likely to enhance success and determine which of these characteristics might contribute to efforts toward developing public environmental policy in the future were investigated. The purpose was accomplished through the design and implementation of a multiple case study utilizing a qualitative research methodology. The sample for this study included six public servants who were identified as actively involved in affecting the development of public …

Update - March 1993, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Loma Linda offers Masters of Arts in Biomedical and Clinical Ethics and assists Claremont with Theological degree

[ Depo-Provera: Contraceptive Dream or Nightmare? ]
-- A Gynecologist's Perspective
-- Some Catholic Moral Reflections

-- Doctor of Philosophy at Claremont

Treat It Right : Alternative Wastewater Systems That Protect Water Quality, Brian Kent

Maine Collection

Treat It Right : Alternative Wastewater Systems That Protect Water Quality

Maine Dept. of Environmental Protection : Maine Dept. of Economic & Community Development, February 1993.

"This handbook was prepared by Maine Tomorrow, a consulting firm in Hallowell. Maine. The handbook was researched, written and designed by Brian Kent; the primary editor and research associate was Alison Truesdale, and Wendy Mahoney did the wordprocessing and desk-top printing."

Systematic Development Of Trans-Theoretically Based Behavioral Risk Management Programs, Galen E. Cole, David R. Holtgrave, Nilka M. Rios

RISK: Health, Safety & Environment (1990-2002)

The authors explain the development and use of a behavioral Risk management strategy. It is designed for developing interventions to change behaviors, e.g., to lower the Risk of AIDS. The advantage of their strategy is said to be its structure combined with flexibility. Intervenors are not restricted to a single model in determining factors most relevant to changing Risky behavior.

Exploiting Structural Differences Among Heteroduplex Molecules To Simplify Genotyping The Dqa1 And Dqb1 Alleles In Human Lymphocyte Typing, Peter A. Zimmerman, Mary Carrington, Thomas B. Nutman

United States Public Health Resources

A novel approach to DNA probe hybridization and heteroduplex analysis, termed directed heteroduplex analysis (DHDA) is presented here to illustrate its utility in simplification of human lymphocyte antigen (HLA)- typing. By strategic labeling of single-stranded probe sequences, DHDA allows the identification of specific heteroduplex structures that contribute to the differentiation of DQAI and DQB1 alleles. Because of the high degree of polymorphism among major histocompatibility complex class 11 second exon sequences, this analysis of 50 different heteroduplex molecules provides evidence of the importance of unpaired bases and mismatched base pairs and their effect on heteroduplex electrophoretic-mobility differences. This strategy is …

The Development Of Microbicides: A New Method Of Hiv Prevention For Women, Christopher J. Elias, Lori L. Heise

HIV and AIDS

A critical review of current epidemiological trends and social science research demonstrates that there is an urgent need for expanding the range of female-controlled HIV prevention methods. Existing efforts to control the spread of HIV infection primarily through the encouragement of a reduction in the number of sexual partners, widespread condom promotion, and the control of other sexually transmitted infections are inadequate for many of the world's women. Underlying gender power inequities severely limit the ability of many women to protect themselves from HIV infection, especially in the absence of a prevention technology they can use, when necessary, without their …

Pus, Pox, Propaganda And Progress: The Compulsory Smallpox Vaccination Controversy In Utah, 1899-1901, Eric L. Bluth

Theses and Dissertations

This thesis examines the compulsory smallpox vaccination controversy in Utah, 1899-1901. It looks at the two smallpox epidemics during 1899-1901 and follows the boards of health attempts to eradicate smallpox primarily by compelling the vaccination of school children.

Dr. Theodore B. Beatty, secretary of the State Board of Health, championed the effort to vaccinate all Utahns; however, the opposition led by Charles W. Penrose, editor of the Deseret Evening News, produced anti-compulsion and vaccination information which influenced Utahns to generally oppose vaccination. Consequently, the legislature passed an anti-compulsory vaccination statute over the governor's veto to annul the courts decision …

Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach

Environmental & Global Health Faculty Research

Aerobiological monitoring was conducted in an experimental room to aid in the development of standardized sampling protocols for airborne microorganisms in the indoor environment. The objectives of this research were to evaluate the relative efficiencies of selected sampling methods for the retrieval of airborne fungal spores and to determine the effect of human activity on air sampling. Dry aerosols containing known concentrations of Penicillium chrysogenum spores were generated, and air samples were taken by using Andersen six-stage, Surface Air System, Burkard, and depositional samplers. The Andersen and Burkard samplers retrieved the highest numbers of spores compared with the measurement standard, …

Gente Joven/Young People: A Dialogue On Sexuality With Adolescents In Mexico, Magaly Marques, John M. Paxman, Judith Bruce

Poverty, Gender, and Youth

This issue of Quality/Calidad/Qualité describes the experience of one adolescent sexuality program, Gente Joven in Mexico. Gente Joven began by acknowledging reality: that the problems related to teenage sexuality will not go away simply by denying their existence. Along the way Gente Joven learned, and is continuing to learn, many lessons about how to build a successful program for adolescents. Here they share their experiences and the Afterword explores in greater depth one particular issue that Gente Joven has identified as its next major challenge: re-examining their work with young people from a gender perspective.

Fertility, Family Size, And Structure: Consequences For Families And Children, Cynthia B. Lloyd

Poverty, Gender, and Youth

In 1989 the Population Council began a research project on the consequences of high fertility at the family level and its implications for the next generation. Since its inception, the project has been supported by Swedish SIDA and has involved the collaboration of researchers from selected developing countries. In countries where there has been limited research on this topic, such as India, Mali, Nigeria, Pakistan, and Senegal, the Population Council provided funding for new studies or for analysis of existing data with the potential for producing insights on this topic. In instances where relevant research was already underway, the Council …

Rethinking Postpartum Health Care, Martha Brady, Beverly Winikoff

Reproductive Health

These proceedings come from papers and discussions as part of the Population Council invitational seminar entited "Rethinking Postpartum Health Care," in 1992. The seminar on postpartum reproductive health was the fifth in a series of seminars convened by the Population Council as part of its Robert H. Ebert Program on Critical Issues in Reproductive Health and Population. The program focuses on four topics: 1) improving and devising new approaches to postpartum care; 2) improving the quality of care in family planning and reproductive health services; 3) managing unwanted pregnancy and preventing the consequences of unsafe abortion; and 4) bringing attention …

The Relationship Of Locus-Of-Control And Altruism To Prehospital Emergency Medical Care Providers Universal Precaution Practices, Joanne L. Wakeham

Health Services Research Dissertations

The purpose of this study was to determine the relationship between locus of control, altruism, occupational risk, and personal factors to the frequency of universal precautions practices of prehospital emergency medical care providers. The effects of OSHA's Occupational Exposure to Bloodborne Pathogens; Final Rule on reducing prehospital emergency medical care providers occupational exposure to bloodborne pathogens were also examined. Prehospital emergency medical care providers from municipal and private EMS agencies in the Tidewater Emergency Medical Services region participated in this study. Prehospital emergency medical care providers self-reported perceptions of locus of control, altruism, occupational risk, and universal precautions practices were …

Analyse Critique Portant Sur La Conversion Des Valeurs Limites Tolérables Dans L'Air (Tlv) Et Des Valeurs Limites Tolérables Dans Les Milieux Biologiques (Blv) En Vue De Les Adapter À Des Horaires De Travail Non-Conventionnels, Jules Brodeur, Kannan Krishnan, Raj Goyal

Rapports de recherche scientifique

Les valeurs limites tolérables d'exposition à des contaminants présents dans l'air (TLV) ont été établies pour des périodes travail d'une durée de 8 heures par jour et ce, pour des semaines comptant 5 journées consécutives de travail. Compte tenu de popularité croissante des horaires de travail non conventionnels, particulier de ceux résultant en un prolongement de la durée d'exposition à des contaminants, il est important de développer des stratégies visant à adapter les valeurs limites tolérables à cette nouvelle réalité.

L'objectif du présent travail est de présenter une analyse critique des principales approches de conversion des valeurs limites tolérables des …

Determining The Effects Of Environmental Issues Instruction On Iowa Teachers, Paul P. Torbert

Dissertations and Theses @ UNI

The purpose of this study was to determine the effectiveness of the Environmental Issues Instruction (eii) program. The study utilized the pre-experimental one-group pre-test post-test survey design with a retrospective pre-test. Statistical analysis of four issue topics revealed 198 participants attained two-tailed probability levels less than the .01 level of significance. Analysis of teacher grade levels revealed kindergarten through eighth grade teachers attained two-tailed probability levels less than the .01 level of significance. Ninth through twelfth grade teachers also attained two-tailed probability levels less than the .01 level of significance with one exception. The researcher concludes that the Environmental Issues …

Localization Of The Gene For Men 2a, Jay B. Lichter, Michael Difilippantonio, Jingshi Wu, Diane Miller, David C. Ward, Paul J. Goodfellow, Kenneth K. Kidd

Henry Ford Hospital Medical Journal

The search for the gene that causes the multiple endocrine neoplasia type 2A (MEN 2A) syndrome is entering a new phase. Genetic linkage studies have localized the gene to the pericentromeric region of chromosome 10. The statistical portion of mapping the gene for MEN 2A is nearly complete and now classical molecular biological/gene mapping techniques will be employed. We have used fluorescence in situ hybridization to estimate the size of the MEN2A region to be about 2 to 5 mb, using some liberal assumptions; at worst the region should contain no more than about 10 mb of non-alphoid DNA. Our …

Microsurgical Lymph Node Dissection For Metastatic Asymptomatic C-Cell Carcinoma, Heinz J. Buhr, Friedrich Kallinowski, Friedhelm Raue, Christian Herfarth

Henry Ford Hospital Medical Journal

In persistent, clinically inapparent medullary thyroid carcinoma, microsurgical dissection of all lymph node compartments of the neck was performed. Between August 1988 and September 1991, 28 cases (mean age 43.3 years) were treated with 38 surgical interventions. Twenty patients had the sporadic form and eight patients the familial form. Unilateral neck dissection resulted in normalization of serum calcitonin (CT) levels even after pentagastrin stimulation in two patients whereas 16 patients exhibited abnormal CT stimulation tests. Eight of ten patients who had bilateral neck dissections had positive pentagastrin test results after surgery. The main postoperative complications included loss of local cutaneous …

Oncogene And Growth Factor Expression In Men 2 And Related Tumors, Jeffrey F. Moley, Göran K. Wallin, Michele B. Brother, Michael Kim, Samuel A. Wells Jr., Garrett M. Brodeur

Henry Ford Hospital Medical Journal

Pheochromocytomas occur sporadically or in individuals affected by inherited syndromes including multiple endocrine neoplasia (MEN) type 2A and 2B, neurofibromatosis, and the von Hippel-Lindau syndrome (vHL). Medullary thyroid carcinomas (MTCs) also occur sporadically or as part of MEN 2A, MEN 2B, and familial MTC. Little is known of the molecular genetic background of these tumors. We have shown previously that activation of the N-ras, H-ras, and K-ras oncogenes does not occur in these tumors, but that deletions of the short arm of chromosome 1 are extremely common (> 60%) and may indicate loss of a suppressor gene in the chromosomal …

High-Sensitivity Serum Calcitonin Assays Applied To Screening For Thyroid C-Cell Disease In Multiple Endocrine Neoplasia Type 2a, Michael M. Kaplan, Glenn M. Stall, Timothy Cummings, Andrew Macaulay, Philippe Motté, Hubert J. Wolfe, Seymour Reichlin, Arman J. Tashjian Jr.

Henry Ford Hospital Medical Journal

Two serum calcitonin assays with sensitivities ≤ 10 pg/mL were compared to our standard radioimmunoassay (sensitivity 100 pg/mL) in multiple endocrine neoplasia type 2A (MEN 2A) screening. Values from the Nichols displacement radioimmunoassay averaged 38% higher than values from the CIS immunoradiometric assay; values from both were highly correlated, r = 0.845. In three individuals, both of the newer assays revealed abnormalities in pentagastrin tests three to four years before abnormalities were detected by the standard assay. Pentagastrin tests after total thyroidectomy were assayed by the newer methods in patients with medullary thyroid carcinoma (MTC) diagnosed at initial testing (group …

Pdn-21 (Katacalcin) And Chromogranin A: Tumor Markers For Medullary Thyroid Carcinoma, Friedhelm Raue, Eberhard Blind, Andreas Grauer

Henry Ford Hospital Medical Journal

The malignant C-cell releases several markets of potential clinical significance into the circulation. To determine the usefulness of these markers for management of medullary thyroid carcinoma (MTC), it is necessary to compare the usefulness of these markers with calcitonin (CT), the classical tumor marker for MTC. Measurement of serum concentrations of the peptide PDN-21 (katacalcin), a carboxyterminal cleavage product of procalcitonin. showed a high correlation with serum CT levels (r = 0.99, P < 0.01, n = 65 patients with MTC). The presence of equimolar concentrations of CT and PDN-21 (CT/PDN-21 molar ratio = 0.95 ± 0.33) indicates the peptide is cosecreted with CT. Stimulation of CT release by intravenous pentagastrin was associated with a parallel increase of PDN-21, providing further evidence of cosecretion of these two peptides. Finally, measurement of either PDN-21 or CT in selective venous catheterization specimens was useful for localization of MTC. Chromogranin A (CgA) levels were also measured in patients with MTC. Circulating levels were elevated in most patients with advanced disease. There was a moderate correlation between CgA and CT serum levels (r = 0.87, P < 0.01. n = 61 patients with MTC). Pentagastrin did not stimulate CgA, and the long half-life of CgA in the circulation did not make it possible to use this peptide for tumor localization by selective venous catheterization. We conclude that measurement of PDN-21 provides an independent assay system for diagnosis, localization, and postoperative management of MTC. whereas CgA measurement is not useful in early diagnosis of MTC and is of limited value for localization or management of progressive disease.

Patterns Of Neoplasia In C-Mos Transgenic Mice And Their Relevance To Multiple Endocrine Neoplasia, Nicholas Schulz, Friedrich Propst, Michael M. Rosenberg, R. Ilona Linnoila, Richard S. Paules, Douglas Schulte, George F. Vande Woude

Henry Ford Hospital Medical Journal

We have previously described a neurological phenotype for transgenic mice carrying the c-Mos proto-oncogene. Pheochromocytomas and C-cell thyroid neoplasms occur in these transgenic lines in patterns that are similar to those seen in multiple endocrine neoplasia type 2 (MEN 2). Characterization of the pathological lesions via immunohistochemistry underscores similarities between MEN 2 and these transgenic mice. When transgenic mice that do not display the MEN 2 phenotype are crossed to a different background, the progeny display the MEN 2 phenotype. Thus the interaction of the background with the transgene is such that it can suppress tumor information. This observation bears …