Digital Commons Network^™

The Prevalence Of Essential Hypertension In Kasigau, Kenya, Lindsay Williams

Mahurin Honors College Capstone Experience/Thesis Projects

Hypertension is the leading cause of cardiovascular disease worldwide. Cardiovascular disease (CVD) is a widespread chronic non-communicable disease (NCD) which is on the rise in developing countries. Evidence based on extensive research studies on risk factors for NCDs suggests that they could be easily significantly decreased by simply controlling their risk factors. Although high blood pressure has been recognized as a leading risk factor for CVD, little research has been done to document the prevalence and incidence of essential hypertension (EH) in lower socioeconomic developing countries. One such country is Kenya. It was found in our research study that Kasigau …

The Evaluation Of Water Quality And Weather Patterns As Indicators For Escherichia Coli In Slaters Creek Watershed In Millersville, Tennessee, Jacqueline Brown

Mahurin Honors College Capstone Experience/Thesis Projects

Water quality sampling was conducted in conjunction with the city of Millersville, Tennessee in order to assess levels of Escherichia coli (E. coli) in Slaters Creek. The city of Millersville is under a storm water National Pollutant Discharge Elimination System (NPDES) permit that requires compliance monitoring. In the past, monitoring of E. coli has resulted in noncompliance with state water quality regulations. A water quality assessment, including E. coli and water quality parameters, was conducted to determine if E. coli levels varied between dates within the study area. Statistical methods were utilized to determine if variations existed between the sampling …

Genome-Wide Mirnaprofiling Of Mantle Cell Lymphoma Reveals A Distinct Subgroup With Poor Prognosis, Javeed Iqbal, Yulei Shen, Yanyan Liu, Kai Fu, Elaine S. Jaffe, Cuiling Liu, Zhongfeng Liu, Cynthia M. Lachel, Karen Deffenbacher, Timothy C. Greiner, Julie M. Vose, Sharathkumar Bhagavathi, Louis M. Staudt, Lisa Rimsza, Andreas Rosenwald, German Ott, Jan Delabie, Elias Campo, Rita M. Braziel, James R. Cook, Raymond R. Tubbs, Randy D. Gascoyne, James O. Armitage, Dennis D. Weisenburger, Timothy W. Mckeithan, Wing C. Chan

United States Public Health Resources

miRNA deregulation has been implicated in the pathogenesis of mantle cell lymphoma (MCL). Using a high-throughput quantitative real-time PCR platform, we performed miRNA profiling on cyclin D1–positive MCL (n = 30) and cyclin D1–negative MCL (n =7) and compared them with small lymphocytic leukemia/ lymphoma (n =12), aggressive B-cell lymphomas (n =138), normal B-cell subsets, and stromal cells.We identified a 19-miRNA classifier that included 6 up-regulated miRNAs and 13 down regulated miRNA that was able to distinguish MCL from other aggressive lymphomas. Some of the up-regulated miRNAs are highly expressed in naive B cells. This miRNAclassifier …

Prioritization Of Biomarker Targets In Human Umbilical Cord Blood: Identification Of Proteins In Infant Blood Serving As Validated Biomarkers In Adults, Nicole Hansmeier, Tzu-Chiao Chao, Lynn R. Goldman, Frank R. Witter, Rolf U. Halden

Environmental and Occupational Health Faculty Publications

Background: Early diagnosis represents one of the best lines of defense in the fight against a wide array of human diseases. Umbilical cord blood (UCB) is one of the first easily available diagnostic biofluids and can inform about the health status of newborns. However, compared with adult blood, its diagnostic potential remains largely untapped.

Objectives: Our goal was to accelerate biomarker research on UCB by exploring its detectable protein content and providing a priority list of potential biomarkers based on known proteins involved in disease pathways.

Methods: We explored cord blood serum proteins by profiling a UCB pool of 12 …

Securing South Africa's Future Grandmothers Against Poverty And Aids As A Model For Social Development Change, Savannah Lynn Eck

Graduate Program in International Studies Theses & Dissertations

Focusing on the role of elder women in South Africa as a lens to understand the central connections among HIV/ AIDS, poverty and Human Security provides a distinct approach to analyze women's contributions to community development and social change. Drawing from the theories of Gender and Development and Human Security, this research aims to highlight HIV/ AIDS as a social and political security issue, while underscoring the vitality of the inclusion of women in the processes of peace building, reconciliation, education and social development. Furthermore, the influential role of elder women in South Africa will serve as a model in …

Using The Framingham Risk Score To Evaluate Immigrant Effect On Cardiovascular Disease Risk In Mexican Americans, Jennifer J. Salinas, Bassent Abdelbary, Jeffrey Wilson, Monir Hossain, Susan P. Fisher-Hoch, Joseph B. Mccormick

Physician Assistant Studies Faculty Publications

Background—This study uses the Framingham Risk Score (FRS) for 10-year cardiovascular disease (CVD) to evaluate differences between Mexican American immigrants and the U.S.-born population. Methods and Results—Data from the Cameron County Hispanic Cohort (N=1,559). Average total risk scores were generated by age group for each gender. Regression analysis was conducted adjusting for covariates and interaction effects. Both women and men in the CCHC sample who were long-term immigrant residents (mean FRS scores women 4.2 with p<.001 vs. men 4.0 with p<.001) or born in the U.S. (mean FRS scores women 4.6 with p<.001 vs. men 3.3 with p<.001) had significantly higher risk scores than immigrants who had only been in this country for less than 10 years. The interaction model indicates that differences between immigrant and native-born Mexican Americans are most greatly felt at lowest levels of socioeconomic status for men in the CCHC. Conclusions—This study suggests that in terms of immigrant advantage in CVD risk, on whom, where, and how the comparisons are being made have important implications for the degree of difference observed.

The Manufacture Of Lifestyle: The Role Of Corporations In Unhealthy Living, Nicholas Freudenberg

Publications and Research

Recently, researchers have debated two views on the connection between lifestyle and health. In the first, health-related lifestyles including tobacco and alcohol use, diet, and physical activity are seen as primary influences on health. In the second, social stratification is the dominant influence with lifestyles simply markers of social status. Neither approach leads to interventions that can reverse the world's most serious health problems. This article proposes that corporate practices are a dominant influence on the lifestyles that shape patterns of health and disease. Modifying business practices that promote unhealthy lifestyles is a promising strategy for improving population health. Corporations …

A Study Of The Link Between Partial Sleep Deprivation And Obesity, Jennifer Pacheco

Honors College Theses

Obesity has become a major health problem with increasing prevalence and is related to multiple medical consequences, such as increased risk for diabetes, heart disease, arthritis, and cancer (Hasler et al., 2004). Due to the limited availability of effective treatment of weight problems, it is necessary to identify potential risk factors for obesity. One factor that has received increased attention is chronic partial sleep deprivation (<7 hours of sleep a night). The decrease in average sleep duration over the past three to four decades has occurred simultaneously with the increase in the prevalence of obesity. Chronic partial sleep deprivation could be a possible risk factor for obesity, but current understanding of the processes linking sleep deprivation to obesity is incomplete. The research will focus on examining the possible pathways through which partial sleep deprivation contributes to the development of obesity: alterations in metabolic pathways and waking behavior, including eating behavior and physical inactivity. The hypothesis behind the proposed study is that increasing sleep duration in obese individuals who experience partial sleep deprivation will lead to a decreased BMI. Research addressing the possible pathways and targeting the amount of sleep will benefit individuals in preventing and/or treating obesity.

Hidden Violence Is Silent Rape: Sexual And Gender-Based Violence In Refugees, Asylum Seekers And Undocumented Migrants In Belgium And The Netherlands, Ines Keygnaert, Nicole Vettenbu, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Although women, young people and refugees are vulnerable to sexual and gender-based violence (SGBV) worldwide, little evidence exists concerning SGBV against refugees in Europe. Using community-based participatory research, 223 in-depth interviews were conducted with refugees, asylum seekers and undocumented migrants in Belgium and the Netherlands. Responses were analysed using framework analysis. The majority of the respondents were either personally victimised or knew of a close peer being victimised since their arrival in the European Union. A total of 332 experiences of SGBV were reported, mostly afflicted on them by (ex-)partners or asylum professionals. More than half of the reported violent …

Arsenic Contamination In Groundwater In Vietnam: An Overview And Analysis Of The Historical, Cultural, Economic, And Political Parameters In The Success Of Various Mitigation Options, Thuy M. Ly

Pomona Senior Theses

Although arsenic is naturally present in the environment, 99% of human exposure to arsenic is through ingestion. Throughout history, arsenic is known as “the king of poisons”; it is mutagenic, carcinogenic, and teratogenic. Even in smaller concentrations, it accumulates in the body and takes decades before any physical symptoms of arsenic poisoning shows. According to the World Health Organization (WHO), the safe concentration of arsenic in drinking water is 10 µg/L. However, this limit is often times ignored until it is decades too late and people begin showing symptoms of having been poisoned.

This is the current situation for Vietnam, …

Adverse Metabolic Response To Regular Exercise: Is It A Rare Or Common Occurrence?, Claude Bouchard, Steven N. Blair, Timothy S. Church, Conrad P. Earnest, James M. Hagberg, Keijo Häkkinen, Nathan T. Jenkins, Laura Karavirta, William E. Kraus, Dabeeru C. Rao, Mark A. Sarzynski, James S. Skinner, Cris A. Slentz, Tuomo Rankinen

Faculty Publications

Background: Individuals differ in the response to regular exercise. Whether there are people who experience adverse changes in cardiovascular and diabetes risk factors has never been addressed.

Methodology/Principle Findings: An adverse response is defined as an exercise-induced change that worsens a risk factor beyond measurement error and expected day-to-day variation. Sixty subjects were measured three times over a period of three weeks, and variation in resting systolic blood pressure (SBP) and in fasting plasma HDL-cholesterol (HDL-C), triglycerides (TG), in insulin (FI) was quantified. The technical error (TE) defined as the within-subject standard deviation derived from these measurements was computed. An …

Cattle Browsing Sagebrush Steppe During Fall: Effects On Plant Community Structure And Influence Of Experience On Cattle Foraging Behavior And Body Weights, Charles A. Petersen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Historic and repetitious spring grazing by livestock, combined with altered fire regimes, has increased the density and abundance of big sagebrush and reduced the frequency of perennial grasses and forbs on many western landscapes. Periodic disturbance is critical for maintaining and improving sagebrush ecosystems. Compared with traditional disturbances – chemical, mechanical, and fire – strategic grazing with livestock offers several benefits. They include creating locally adapted cattle that can rejuvenate sagebrush steppe, which reduces costs associated with mechanical and chemical rejuvenation treatments and feeding cattle during winter, the major cost of ranch operation.

I evaluated the practicality of strategically timed …

Effects Of Temperature On Emergence And Seasonality Of West Nile Virus In California, David M. Hartley, Christopher M. Barker, Arnaud Le Menach, Tianchan Niu, Holly Gaff, William K. Reisen

Biological Sciences Faculty Publications

Temperature has played a critical role in the spatiotemporal dynamics of West Nile virus transmission throughout California from its introduction in 2003 through establishment by 2009. We compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (BT), and the fundamental reproductive ratio (R₀) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral amplification. Maps of BT and R₀ were created at 20-km scale and compared throughout California to seroconversions in sentinel chicken flocks at half-month intervals. Overall, estimates of BT and …

Why Access Barriers To Primary Care Exist For People With Mobility Disabilities: A Mixed Methods Study Of Health Care Administrators, Jennifer Renee Pharr

UNLV Theses, Dissertations, Professional Papers, and Capstones

Previous studies have been conducted to assess the barriers that limit access to health care services for people with disabilities. However, no study has been conducted to understand why barriers exist. Do practice administrators lack knowledge of the Americans with Disabilities Act (ADA) or is cost the issue? The purpose of this study was to examine why structural and equipment barriers exist that limit access to primary health care for people with disabilities.

A convergent parallel mixed methods design was employed. Practice administrators were selected for this study because of their oversight of the budget, equipment purchasing, facility operations and …

Individual Resilience, Social Support, And Health Risk Behaviors In Adolescents And Young Adults: Study On Cross-Sectional And Longitudinal Samples, Chuong Hong Nguyen

Graduate Theses and Dissertations

Resilience is considered the ability that a person gains positive achievements despite exposure to significantly adverse life conditions. However, a majority of previous research has focused on human developmental tasks or academic achievements. Evidence of resilience on health risk behaviors has not been comprehensively established yet. The purposes of this dissertation were to extend the existing literature about the stability of resilience through time, to examine how the resilience scale concurrently and prospectively predict resilience statuses, and to explore effects of Social support over a long period of lifetime. The dissertation used a secondary database from the public-use version of …

Aptamer-Based Spr Biosensor For Detection Of Avian Influenza Virus, Hua Bai

Graduate Theses and Dissertations

Rapid and specific detection of avian influenza (AI) virus is urgently needed with the concerns over the outbreaks of highly pathogenic H5N1 avian influenza in animal and human infection. Aptamers are artificial oligonucleic acid that can specifically bind to target molecules. They show comparable affinity for target virus and better thermal stability than monoclonal antibodies. Those advantages make aptamers promising candidates in diagnostic and detection applications. The goal of this research was to use DNA&ndashaptamer as the specific recognition element in a portable surface plasmon resonance (SPR) biosensor for detection of AI H5N1 virus in poultry.

A SPR biosensor was …

Risk Factors For Secondary Infertility Among Women In Karachi, Pakistan., Neelofar Sami, Tazeen S. Ali, Saba Wasim, Sarah Saleem

Community Health Sciences

Background: Secondary infertility in developing countries is mostly attributable to blockage of the fallopian tubes due to adhesions caused by reproductive tract infections. There is a dearth of information on the prevalence and causes of secondary infertility from Pakistan. This paper presents results on factors associated with secondary infertility among married women in Karachi, Pakistan. Methods: A matched case-control study was conducted. Cases were women aged 15-35 years with history of at least one previous conception and currently seeking treatment for secondary infertility. Controls were women residing in the neighborhood of cases with at least one live birth and not …

Adult Attachment Style, Spirituality, And Religiosity Among Individuals In Treatment For Substance Use Disorders, E Gail Horton, Naelys Diaz, Michael Weiner, Tammy Malloy

Florida Public Health Review

Spirituality and religiosity are considered to be protective factors in the treatment of substance abuse. Little is known, however, about how adult attachment style may be associated with levels of spirituality and religiosity. This study explored adult at- tachment styles among individuals in inpatient treatment for substance abuse and dependence and determined if there were significant differences between spirituality and/or religiosity variables by adult attachment style within the sample. Results indicated that neither of the religiosity variables varied by attachment style, but that one of two subscales in the spirituality measure, existential purpose and meaning, did vary significantly. Specifically, differences …

Risiko Hiperkolesterolemia Pada Pekerja Di Kawasan Industri, Krisnawaty Bantas, Farida Mutiarawaty Tri Agustina, Dinie Zakiyah

Kesmas

Hiperkolesterolemia adalah faktor risiko penting penyakit kardiovaskuler yang menjadi penyebab utama kematian dan kesakitan di seluruh dunia. Penyakit kardiovaskuler yang berdampak kerugian ekonomi dan penurunan produktivitas kerja dapat dicegah dengan mengendalikan faktor risiko terse- but. Penelitian ini bertujuan untuk mengetahui prevalensi dan faktor risiko hiperkolesterolemia di kalangan pekerja di kawasan industri Pulo Gadung tahun 2006. Penelitian yang menggunakan desain studi cross sectional ini mengamati variabel independen kebiasaan merokok, konsumsi alkohol, ke- biasaan olahraga, dan obesitas. Populasi penelitian adalah pekerja di 7 jenis perusahaan di kawasan industri Pulo Gadung yang berusia 20 tahun ke atas. Penelitian menemukan prevalensi hiperlipidemia 21,1%; nilai …

Global Impacts Of Media On Tobacco Use Among Adolescents: A Comparative Analysis Of The United States And China, Katherine Theresa Lesyna

Scripps Senior Theses

Tobacco use is responsible for five million deaths annually and is one of the leading causes of preventable death worldwide. Many smokers initiate smoking behavior during adolescence. Adolescent smoking rates have been on the rise and there are a variety of different factors that contribute to the initiation of smoking behavior. While the World Health Organization (WHO) and the National Cancer Institute (NCI) have endorsed the claim that smoking in movies increases adolescents’ risk of initiating smoking, few studies have examined the impact of media on adolescent smoking in China following the expansion of transnational tobacco companies. The aim of …

Molecular Distinctions Between Pediatric And Adult Mature B-Cell Non-Hodgkin Lymphomas Identified Through Genomic Profiling, Karen Deffenbacher, Javeed Iqbal, Warren Sanger, Yulei Shen, Cynthia Lachel, Zhongfeng Liu, Yanyan Liu, Megan Lim, Sherrie Perkins, Kai Fu, Lynette Smith, James Lynch, Louis Staudt, Lisa M. Rimsza, Elaine Jaffe, Andreas Rosenwald, German Ott, Jan Delabie, Elias Campo, Randy Gascoyne, Mitchell Cairo, Dennis Weisenburger, Timothy Greiner, Thomas Gross, Wing Chan

United States Public Health Resources

Burkitt lymphoma (BL) predominates in pediatric patients, whereas diffuse large B-cell lymphoma (DLBCL) is uncommon. In contrast to adults, BL and DLBCL are treated similarly in children and both entities have superior outcomes in children compared with adults. Gene expression profiling (GEP) and miRNA expression profiling clearly differentiated pediatric DLBCL from BL, forming distinct clusters regardless of patient age. However, pathway analysis of GEP data identified minor differences between corresponding pediatric and adult tumors. Predominance (6:1) of the germinal center B-cell subtype to activated B-cell subtype was found among pediatric DLBCL. Two cases were molecularly classified as primary mediastinal B-cell …

High And Persistent Hiv Seroincidence In Men Who Have Sex With Men Across 47 U.S. Cities, Marta-Louise Ackers, Alan E. Greenberg, Carol Y. Lin, Bradford N. Bartholow, Adrian Hirsch Goodman, Michael Longhi, Marc Gurwith

Epidemiology Faculty Publications

Objective

To provide HIV seroincidence data among men who have sex with men (MSM) in the United States and to identify predictive factors for seroconversion.

Methods

From 1998–2002, 4684 high-risk MSM, age 18–60 years, participated in a randomized, placebo-controlled HIV vaccine efficacy trial at 56 U.S. clinical trial sites. Demographics, behavioral data, and HIV status were assessed at baseline and 6 month intervals. Since no overall vaccine efficacy was detected, data were combined from both trial arms to calculate HIV incidence based on person-years (py) of follow-up. Predictors of seroconversion, adjusted hazards ratio (aHR), were evaluated using a Cox proportional …

Obesity Prevalence, Weight-Related Beliefs And Behaviors Among Low-Income Ethnically Diverse National Job Corps Students, Jamie S. Bodenlos, Milagros C. Rosal, Diane Blake, Celeste Lemay, Diane Elfenbein

Journal of Health Disparities Research and Practice

The obesity rates of Job Corps students, a predominantly ethnic minority and low income group of youth, are unknown. The purpose of this project was to examine obesity rates among these youth as well as their weight-related perceptions and behavior. First, medical charts (N=641) of all Job Corps students (ages 16-25) who were enrolled in the program in the past year were examined for height and weight. In the second phase of the study, 344 Job Corp students were recruited and information on weight perceptions, knowledge of obesity consequences, and weight loss behavior were examined. Almost half of the participants …

The Significance Of A K-12 Diabetes-Based Science Education Program For Tribal Populations: Evaluating Cognitive Learning, Cultural Context, And Attitudinal Components, Carolee D. Francis, Doug Coulson, Bonnie Kalberer, Lemyra Debruyn, William Freeman, Janet Belcourt

Journal of Health Disparities Research and Practice

Preventing and reducing the onset of type 2 diabetes among American Indian/Alaska Native youth requires ground-breaking strategies to affect knowledge, attitudes, and cognitive decision-making skills. In an unparalleled endeavor to address the growing epidemic of type 2 diabetes in tribal communities, a K-12 Diabetes Education in Tribal Schools (DETS) curriculum was created by eight tribal colleges and three federal agencies. This article highlights the results of the implementation phase, the final evaluation step in acquiring and measuring student knowledge and attitude gains through pre-post standardized assessment.

Modeling Health Inequities Research In Context And The Minority Researcher’S Role, Ari Mwachofi, Ngure Wamwachofi

Journal of Health Disparities Research and Practice

Current health inequities research templates are flawed and self-defeating because they do not include historical inequalities as the central context that points to the root causes of health inequities. The context includes structural malformations which are products of the history of colonization and slavery that created racial separation and hierarchies which established Whites as the dominant group and non-Whites (minorities) as the subordinate group. Consequently it is difficult for mainstream researchers to capture the minorities’ core knowledge necessary for the creation of relevant and effective interventions for fundamental and sustainable improvement of their health. This paper proposes a health inequities …

A Social Controversy: Autism Spectrum Disorder's Correlation To The Measles-Mumps-Rubella Vaccination, Lindsay A. Frye

Senior Honors Theses

A 1998 research study lead by Dr. Andrew Wakefield linked the measles-mumps-rubella (MMR) vaccination as a probable cause to autism spectrum disorder. This publication has started a significant debate among healthcare professionals and instigated an anti-vaccination movement within the general population. This vaccination controversy was started by parents who readily accepted Wakefield’s findings as truth and frequently would choose to withdrawal the administration of vaccinations from their children’s care plans. There has also been disapproval by healthcare professionals over Wakefield’s study since numerous research teams have been unable to replicate his findings. This disagreement surrounding the MMR vaccination is likely …

Hiv/Sti Risk Factors Among African-American Students Attending Predominantly White Universities, Marya L. Shegog, Lisa Lindley, Melva Thompson-Robinson, David Simmons, Donna Richter

Journal of Health Disparities Research and Practice

Introduction: The majority of African American college students in the U.S. attend predominantly white institutions (PWIs). However, there is minimal research examining this population’s HIV/STI risk behaviors. The purpose of this investigation was to assess HIV/STI behavioral risk factors among African American college students (aged 18 – 24years) attending PWIs. (n = 2,568)

Methods: Backwards step-wise logistic regression analyses were conducted to determine factors associated with a positive HIV/STI diagnosis (past year) among sexually active African American college students who participated in the Spring, 2006 National College Health Assessment.

Findings: Nine factors were significantly associated with an HIV/STI diagnosis among …

Prioritizing Interventions And Research To Address The Cancer Disparities Of Arizona’S American Indian Population, Norman J. Petersen, Sujata Joshi, Tim Flood, Kathryn Coe

Journal of Health Disparities Research and Practice

The aim of the Southwest American Indian Collaborative Network (SAICN) is to reduce cancer disparities by closing the gap between community needs and the promise of cancer prevention and cure through participatory education, training and research programs. In an effort to provide evidence-based recommendations and promote the use of relevant data in tribal communities, the SAICN Data and Evaluation Core developed two comparison matrices that present scientifically sound practices for use by community health decision makers in prioritizing activities likely to reduce the irrespective community’s burden of cancer. In their current configurations, Matrix A considers those cancers for which prevention …

Application Of The Pen-3 Model In A Diabetes Prevention Intervention, Joan E. Cowdery, Shandowyn Parker, Amy Thompson

Journal of Health Disparities Research and Practice

More effective strategies for addressing health issues in African American communities are needed. As part of a three year NIH funded Project Export grant, this community campus partnership used community-based participatory research principles and thePEN-3 Cultural Framework to develop a culturally specific, locally relevant intervention to prevent Diabetes among African-Americans. A comprehensive needs assessment which included 13 elicitation interviews, 3 focus groups, and 217 surveys resulted in identifying major themes including overall lack of knowledge regarding Diabetes,issues of denial and stigma, sense of inevitability, influence of family on perceptionsand behaviors, communication issues with health care providers, and lack of culturally …

Comparing Risk Factors Of Hiv Among Hijra Sex Workers In Larkana And Other Cities Of Pakistan: An Analytical Cross Sectional Study, Arshad Altaf, Aysha Zahidie, Ajmal Agha

Community Health Sciences

Background

In 2005, Pakistan was first labeled as a country with concentrated epidemic of Human Immunodeficiency Virus (HIV). This was revealed through second generation surveillance conducted by HIV/AIDS Surveillance Project (HASP). While injection drug users (IDUs) were driving the epidemic, subsequent surveys showed that Hijra (transgender) sex workers (HSWs) were emerging as the second most vulnerable group with an average national prevalence of 6.4%. An exceptionally high prevalence (27.6%) was found in Larkana, which is a small town on the right bank of river Indus near the ruins of Mohenjo-Daro in the province of Sindh. This paper presents the risk …