Digital Commons Network^™

Patent Landscape Of Helminth Vaccines And Related Technologies, Jon R. Cavicchi, Stanley P. Kowalski, John Schroeder, Rayna Burke, Jillian Michaud-King

Law Faculty Scholarship

Executive Summary This report focuses on patent landscape analysis of technologies related to vaccines targeting parasitic worms, also known as helminths. These technologies include methods of formulating vaccines, methods of producing of subunits, the composition of complete vaccines, and other technologies that have the potential to aid in a global response to this pathogen. The purpose of this patent landscape study was to search, identify, and categorize patent documents that are relevant to the development of vaccines that can efficiently promote the development of protective immunity against helminths. The search strategy used keywords which the team felt would be general …

Critical Analysis Of Contemporary Public Health Genomics And Needs Assessment For Public Health Genomics Course Curriculum, Kim London

Master of Public Health Program Student Publications

Objective: To analyze the need for increased content on genomics in Public Health (PH) academic curriculum.

Methods: A literature synthesis was performed of various genetic science studies. Results were assessed with regard to the number and type of genomic studies published, cost to perform genetic analyses, health care provider and the public’s use and understanding of genetic testing capabilities. A search was conducted and assessment performed of public health genomics curriculum at accredited public health educational programs.

Results: The cost to sequence a single genome declined from $10 million in 2007 to under $10 thousand in 2012. This cost reduction …

What Are Parents' Perceptions On Immunizations Causing Autism Spectrum Disorders?, Shanae Nicole Blake

Theses Digitization Project

The purpose of this study was to identify parental perceptions on immunizations causing Autism Spectrum Disorders (ASDs), and identify whether or not these perceptions influenced whether or not a parent vaccinated their child. If parents are educated on vaccinations, and understand that numerous studies have been conducted proving immunizations do not cause autism, it may prevent a host of possible problems that may arise in the future.

Differences In Demographic, Behavioral, And Biological Variables Between Those With Valid And Invalid Accelerometry Data: Implications For Generalizability, Paul D. Loprinzi, Bradley J. Cardinal, Carlos J. Crespo, Gary R. Brodowicz, Ross E. Andersen, Ellen Smit

Community Health Faculty Publications and Presentations

Background: The exclusion of participants with invalid accelerometry data (IAD) may lead to biased results and/or lack of generalizability in large population studies. The purpose of this study was to investigate whether demographic, behavioral, and biological differences occur between those with IAD and valid accelerometry data (VAD) among adults using a representative sample of the civilian noninstitutionalized U.S. population. Methods: Ambulatory participants from NHANES (2003-2004) who were 20-85 years of age were included in the current study and wore an ActiGraph 7164 accelerometer for 7 days. A "valid person" was defined as those with 4 or more days of at …

Molecular Epidemiology Of Early And Acute Hiv Type 1 Infections In The United States Navy And Marine Corps, 2005–2010, Richard A. Heipertz, Eric Sanders-Buell, Gustavo Kijak, Shana Howell, Michelle Lazzaro, Linda L. Jagodzinski, John Eggleston, Sheila Peel, Jennifer Malia, Adam Armstrong, Nelson L. Michael, Jerome H. Kim, Robert J. O'Connell, Paul T. Scott, David Brett-Major, Sodsai Tovanabutra

Journal Articles: Epidemiology

The U.S. military represents a unique population within the human immunodeficiency virus 1 (HIV-1) pandemic. The last comprehensive study of HIV-1 in members of the U.S. Navy and Marine Corps (Sea Services) was completed in 2000, before large-scale combat operations were taking place. Here, we present molecular characterization of HIV-1 from 40 Sea Services personnel who were identified during their seroconversion window and initially classified as HIV-1 negative during screening. Protease/reverse transcriptase (pro/rt) and envelope (env) sequences were obtained from each member of the cohort. Phylogenetic analyses were carried out on these regions to determine relatedness within the cohort and …

Documentation Of Hiv Prevention Research And Programmatic Learnings From India—Selected Peer-Reviewed Journal Publications From The Knowledge Network Project (Volume 1), Population Council

HIV and AIDS

Over the past decade (2000–11), India has achieved dramatic successes in reversing the HIV epidemic. These successes are largely due to the implementation of upscaled HIV-prevention interventions by the National AIDS Control Organization, two other donors, and nongovernmental organizations, under the National AIDS Control Program III. As the epidemic in India is concentrated in vulnerable subpopulations, these interventions were focused on high-risk groups. It is important to understand the lessons learned from the implementation of HIV-prevention programs and the vulnerabilities that need to be addressed to reach the goal of zero new infections. To support this understanding, the Population Council …

Comparing Two-Year Community College And Four-Year University Student Social And Behavioral Sexually Transmitted Infection Risk Factors, Oswald M. Attin

Faculty Dissertations

Sexually transmitted infections (STIs) could cause ectopic, cervical cancer, infertility, and organ damage to the heart, kidneys, and brain. This study compared several behavioral risk factors of STIs (condom use, number of sexual partners, type of sex (anal or vaginal) and drinking habits) between two distinct educational settings and their association with socioeconomic risk factors such as low income and parent’s lower level of education that are known to increase the incidence of STIs among college-aged students. This study was based on the precautionary-health-behavior model, where individuals act regardless of consequences, and the health-behavior-change model, where individual behaviors either increase …

Factors Affecting Uptake Of, And Adherence To, Treatment For Latent Tuberculosis Infection In Ventanilla, Peru, Mariano Matias Iberico Lozada

Master of Public Health Program Student Publications

In Peru, treatment for latent tuberculosis infection (LTBI) with isoniazid is free for all people younger than 20 who have been in close contact with a person with active pulmonary tuberculosis (TB). Despite the availability of this drug therapy within the context of a TB control program that exceeds the international standards for TB care, very few children access, and even fewer complete a full course of treatment. This study was done in order to understand which factors contribute to latent tuberculosis infection treatment uptake and adherence, and whether a socio-economic intervention could improve uptake and adherence of treatment for …

Parental Feeding Practices In Mexican American Families: Initial Test Of An Expanded Measure, Jeanne M. Tschann, Steven E. Gregorich, Carlos Penilla, Lauri A. Pasch, Cynthia L. De Groat, Elena Flores, Julianna Deardorff, Louise C. Greenspan, Nancy F. Butte

School of Education Faculty Research

Background: Although obesity rates are high among Latino children, relatively few studies of parental feeding practices have examined Latino families as a separate group. Culturally-based approaches to measurement development can begin to identify parental feeding practices in specific cultural groups. This study used qualitative and quantitative methods to develop and test the Parental Feeding Practices (PFP) Questionnaire for use with Mexican American parents. Items reflected both parent’s use of control over child eating and child-centered feeding practices.

Methods: In the qualitative phase of the research, 35 Latino parents participated in focus groups. Items for the PFP were developed from focus …

The Birds, The Bees And The Stds: A Content Analysis Of Teenage Sexual Health Internet Message Boards, Jessica A. Kruse

Master of Public Health Program Student Publications

Recent research indicates that teenagers rely on electronic media for information about sexual health. In the present study the author examined the online information-seeking behaviors of male and female teenagers on two Internet message boards. Content analyses were conducted on user questions about pregnancy, birth control and sexually transmitted infections. Results indicated that (1) teens are very concerned about pregnancy but are less concerned about STIs, and (2) teens are not comfortable with negotiating condom use or STI testing with sexual partners. The outcomes from this study support the previous findings that teens do discuss sexual health on the Internet …

Association Between Childhood Adversities And Adulthood Depressive Symptoms In South Korea: Results From A Nationally Representative Longitudinal Study, Seung-Sup Kim, Hyobum Jang, Hyoung Yoon Chang, Young Su Park, Dong Woo Lee

Environmental and Occupational Health Faculty Publications

Objective To examine how childhood adversity (ie, parental death, parental divorce, suspension of school education due to financial strain or being raised in a relative's house due to financial strain) is associated with prevalence and incidence of adulthood depressive symptoms and whether this association differs by gender and by age in South Korea.

Design Prospective cohort design.

Setting Nationally representative longitudinal survey in South Korea.

Participants 11 526 participants in South Korea.

Outcome measure Prevalence and incidence of adulthood depressive symptoms were assessed as a dichotomous variable using the Centers for Epidemiologic Studies Depression (CES-D) Scale in 2006 and 2007. …

The Hispanic Paradox And Older Adults’ Disabilities: Is There A Healthy Migrant Effect?, Esme Fuller Thomson, Amini Nuru-Jeter, Dawn M. Richardson, Ferrah Raza, Meredeth Minkler

Community Health Faculty Publications and Presentations

The “Hispanic Paradox” suggests that despite rates of poverty similar to African Americans, Hispanics have far better health and mortality outcomes, more comparable to non-Hispanic White Americans. Three prominent possible explanations for the Hispanic Paradox have emerged. The “Healthy Migrant Effect” suggests a health selection effect due to the demands of migration. The Hispanic lifestyle hypothesis focuses on Hispanics’ strong social ties and better health behaviors. The reverse migration argument suggests that the morbidity profile in the USA is affected when many Hispanic immigrants return to their native countries after developing a serious illness. We analyzed data from respondents aged …

Transmission Rate In Partial Differential Equation In Epidemic Models, Alaa Elkadry

Theses, Dissertations and Capstones

The rate at which susceptible individuals become infected is called the transmission rate. It is important to know this rate in order to study the spread and the effect of an infectious disease in a population. This study aims at providing an understanding of estimating the transmission rate from mathematical models representing the population dynamics of an infectious diseases using two different methods. Throughout, it is assumed that the number of infected individuals is known. In the first chapter, it includes historical background for infectious diseases and epidemic models and some terminology needed to understand the problems. Specifically, the partial …

Characterization Of Antimicrobial-Resistant Staphylococcus Spp. In Food Animals And Retail Meat, Kanika Bhargava

Wayne State University Dissertations

Antimicrobial resistance in Staphylococcus spp. is a worldwide epidemic concern in hospital and community settings. Food animals and retail meat are important reservoirs of these pathogens that can pose potential threat to humans. In this dissertation, we aimed to investigate the molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Coagulase-negative Staphylococci (MRCoNS) in food animals and retail meat to provide insight into the role of agricultural environment in transmitting bacteria of human clinical significance. Furthermore, the potential application of phytochemicals as antimicrobials and antimicrobial adjuvants to control MRSA infections was explored.

CoNS recovered from food animals were characterized by …

The Feasibility Of Implementing The Acp-215 At The Dayton Community Blood Center: A Cost-Benefit Analysis, Angela Albrecht

Master of Public Health Program Student Publications

The community blood supply is a limited resource with a relatively short shelf-life. To ensure an adequate supply, a balance must be maintained between the numbers of donors providing blood and blood products required by hospitals to meet patient needs. Any change in the number of blood donors or in the volume of blood required by hospitals can create a blood shortage. During times of disaster, a blood shortage may be inevitable. Additional strategies must be in place to ensure availability of blood for essential transfusions across the community. Cryopreservation of red blood cells to build and maintain a blood …

Complete Genome Sequence Of The Epidemic And Highly Virulent Ctx-M-15-Producing H30-Rx Subclone Of Escherichia Coli St131, Paal S. Andersen, Marc Stegger, Maliha Aziz, Tania L. Contente-Cuomo, Henry S. Gibbons, Paul Keim, Evgeni V. Sokurenko, James R. Johnson, Lance B. Price

Environmental and Occupational Health Faculty Publications

We report the complete genome sequence, including five complete plasmid sequences, of Escherichia coli ST131 isolate JJ1886. The isolate was obtained in 2007 in the United States from a patient with fatal urosepsis and belongs to the virulent, CTX-M-15-producing H30-Rx sublineage.

Situation Analysis Of Programs To Meet The Hiv Prevention, Care, And Treatment Needs Of Persons With Disabilities In Ghana, Uganda, And Zambia, Waimar Tun, Jerry Okal, Katie D. Schenk, Meredith Sheehy, Emmanuel Kuffour, Selina F. Esantsi, Hilary Asiah, Grimond Moono, Felix Mutale, Rita Kyeremaa, Edson Ngirabakunzi, Atwijukire Justus

HIV and AIDS

National HIV strategic plans, HIV-related services, and HIV outreach efforts have tended to overlook persons with disabilities, and persons with disabilities are not reached by general HIV prevention, care, support, and treatment campaigns and services. To increase our understanding of how to make HIV programming more inclusive for persons with disabilities, HIVCore and partners conducted a three-country situation analysis (Uganda, Zambia, and Ghana). The study explored existing HIV services for persons with disabilities and determined the factors affecting their access to and use of HIV/sexual and reproductive health (SRH) services. Key findings: Persons with disabilities experience greater sexual vulnerability to …

Astrue V. Capato: Forcing A Shoe That Doesn't Fit, Courtney Hannon

Journal of Health Care Law and Policy

No abstract provided.

Getting To The Other Side: An Exploration Of The Head And Neck Cancer Treatment Experience, Heather M. Wallace

Theses and Dissertations--Gerontology

Diagnosis of head and neck squamous cell carcinoma (HNSCC) presents a multifarious problem. Late stage diagnosis, uncertainty regarding appropriate clinical treatment, as well as the high potential for disfigurement and functional loss resulting in diminished quality of life, contributes to anxiety, stress, fear, and uncertainty throughout the cancer treatment experience. This qualitative study sought to explore the cancer treatment experience of adults with newly diagnosed HNSCC, including laryngeal, esophageal, and oral cancers. Study participants were recruited from the University of Kentucky Ear Nose and Throat Clinic in Lexington KY. Participants agreed to be interviewed after receipt of their cancer diagnosis …

The Relationship Between Parental And Adolescent Religiosity Factors And Adolescent Sexual Risk-Taking Among Older Adolescents In The Anglophone/Latin Caribbean, Karen Christoffel Flowers

Dissertations

Problem: Sexually active youth across the Anglophone/Latin Caribbean have been identified as among the most-at-risk for HIV infection. Studies conducted in the United States have identified parental and religiosity factors associated with adolescent sexual risk-taking, but these relationships remain largely unexplored in the Caribbean region.

Method: This cross-sectional study, based on survey data generated by the Seventh-day Adventist Caribbean Youth Survey, investigated the relationship between parental and adolescent religiosity factors and sexual at-risk behaviors reported by adolescents ages 16-18 years attending Seventh-day Adventist Church-operated secondary schools across the region. Pearson correlations and multiple regression analyses were used to assess the …

The Children And Parents In Focus Project: A Population-Based Cluster-Randomised Controlled Trial To Prevent Behavioural And Emotional Problems In Children, R. Salari, H. Fabian, Ron Prinz, S. Lucas, I. Feldman, Amanda Fairchild, A. Sarkadi

Faculty Publications

Background: There is large body of knowledge to support the importance of early interventions to improve child health and development. Nonetheless, it is important to identify cost-effective blends of preventive interventions with adequate coverage and feasible delivery modes. The aim of the Children and Parents in Focus trial is to compare two levels of parenting programme intensity and rate of exposure, with a control condition to address impact and cost-effectiveness of a universally offered evidence-based parenting programme in the Swedish context. Methods/Design: The trial has a cluster randomised controlled design comprising three arms: Universal arm (with access to participation in …

Searching For Health Information On The Internet : The Experiences Of Western Australian Adolescents, Lee-Anne Martins

Theses : Honours

Adolescents readily engage in online entertainment pursuits, however, it is their online social activities and health information searches that encourage psychosocial development and influence identity formation and autonomy. Considerable research has been completed on various aspects of adolescents’ encounters with online health information (for example, see Percheski & Hargittai, 2011), yet minimal research has been conducted using Australian adolescents. This study extends existing research utilising Western Australian adolescents who have used the Internet to obtain health information. The areas explored include how Western Australian adolescents search for online health information, by means of which devices, and their experiences of using …

Task-Based Noise Exposures For Farmers Involved In Grain Production, Michael J. Humann, Wayne T. Sanderson, Kelley J. Donham, Kevin M. Kelly

Epidemiology and Environmental Health Faculty Publications

Few studies have been done examining noise exposures associated with agricultural tasks. This study was conducted to address that research gap by calculating the noise exposures for tasks and equipment associated with grain production and assessing the variability in those exposures. An additional aim of this study was to identify tasks and equipment that could be targeted for intervention strategies as a means toward reducing the total noise exposures of farmers and farm workers. Through the use of personal noise dosimetry and direct observation, over 30,000 one-minute noise exposure measurements and corresponding task and equipment data were collected on 18 …

Desert In The Springs: Ethnography Of A Food Desert, Margeaux Alana Chavez

USF Tampa Graduate Theses and Dissertations

"Food desert" commonly describes food insecure areas with few fresh food outlets. Though used in a number of sources, the definition of "food desert" remains largely undeveloped and research is often deficit oriented, failing to account for community assets that may exist within food deserts but are underutilized or under-supported. Using an assets-based, ethnographic approach, this study combines GIS and survey methodology with participant observation and qualitative interviews to assess the potential positive effect of urban agriculture on food accessibility in Sulphur Springs, a USDA identified urban food desert in Tampa, Florida.

Ethnographic data suggest that within this neighborhood, residents …

Impulsivity Like Traits And Risky Driving Behaviors Among College Students, Matthew R. Pearson, Elaine M. Murphy, Ashley N. Doane

Psychology Faculty Publications

The present study examined the predictive effects of five impulsivity-like traits (Premeditation, Perseverance, Sensation Seeking, Negative Urgency, and Positive Urgency) on driving outcomes (driving errors, driving lapses, driving violations, cell phone driving, traffic citations, and traffic collisions). With a convenience sample of 266 college student drivers, we found that each of the impulsivity-like traits was related to multiple risky driving outcomes. Positive Urgency (tendency to act impulsively when experiencing negative affect) was the most robust predictor of risky driving outcomes. Positive Urgency is a relatively newly conceptualized impulsivity-like trait that was not examined in the driving literature previously, suggesting a …

The Core Competencies For Public Health Professionals, Center For Leadership In Public Health Practice

Florida Public Health Training Center

Core competencies for public health professionals are competencies that represent a set of skills, knowledge, and attitudes necessary for the broad practice of public health, as they apply to front-line staff, senior-level staff, and supervisory and management staff. We will describe the Core Competencies for Public Health Professionals by defining the related key terminology, reviewing how the Core Competencies are designed for all public health professionals at the various stages of their career, and presenting the Domains of the Core Competencies.

Experiences Of Kenyan Healthcare Workers Providing Services To Men Who Have Sex With Men: Qualitative Findings From A Sensitivity Training Programme, Elise M. Van Der Elst, Evans Gichuru, Anisa Omar, Jennifer Kanungi, Zoe Duby, Miriam Midoun, Sylvia Shangani, Susan M. Graham, Adrian D. Smith, Eduard J. Sanders, Don Operario

Community & Environmental Health Faculty Publications

Introduction

Men who have sex with men (MSM) in Kenya are at high risk for HIV and may experience prejudiced treatment in health settings due to stigma. An on-line computer-facilitated MSM sensitivity programme was conducted to educate healthcare workers (HCWs) about the health issues and needs of MSM patients.

Methods

Seventy-four HCWs from 49 ART-providing health facilities in the Kenyan Coast were recruited through purposive sampling to undergo a two-day MSM sensitivity training. We conducted eight focus group discussions (FGDs) with programme participants prior to and three months after completing the training programme. Discussions aimed to characterize HCWs’ challenges in …

Organizational Response To Perceptual Risk: Managing Substantial Response To Unsubstantiated Events, Elizabeth L. Petrun

Theses and Dissertations--Communication

Analysis and perceived severity of risk influences organizational decisions to anticipated threats. As economic development and technology improve our standards of living, they also create new challenges to conceptualizing concrete and abstract threats. Organizations that face new threats, along with agencies that oversee these organizations, produce tightly coupled systems that increase risks for direct, indirect, and future stakeholders (Perrow, 1999). Natural disasters, political misbehavior, organizational corruption, financial collapse, food and water contaminations, chemical or nuclear accidents, international tension, to name a few, all present risks and challenges. Unfortunately, many of these situations endanger the lives and well-being of persons. The …

Sanitation Infrastructure, Medicinal Plant Use And Diarrhea In Rural Costa Rican Communities, Travis Clifford Sondgerath

Open Access Theses

Diarrhea is estimated to be responsible for 3.3 million deaths a year and is particularly problematic in the developing world among children. The Millennium Development Goals established by the United Nations has set a goal of reducing mortality among children by two thirds during the new millennium. However due to the nature of diarrhea it is often difficult to study its patterns, distribution, and determinants.

This study presents an analysis of the relationship between diarrhea and sanitation infrastructure and medicinal plant use in 4 rural Costa Rican communities. Over the past few decades' access to clean drinking water and municipal …

The Relationship Between Bullying And Weight Management Behaviors In High School Aged Youth, Lindsey Simpson-Pedigo

Open Access Theses

Purpose: Examined whether high-school students' body mass index (BMI) classification was related to being bullied, and whether being bullied mediates the student's likelihood of practicing unhealthy weight management and weight loss behaviors.

Methods: This study was a secondary data analysis of cross-sectional data obtained by the Youth Risk Behavior Surveillance System (YRBSS) 2011. Mediation analyses were used to assess relationships between weight status, being bullied and use of unhealthy weight management and weight loss behaviors.

Results: The sample consisted of 15,425 high-school students in the United States drawn from a nationally representative survey. In this sample, 15.8% were overweight and …