Digital Commons Network^™

Effects Of Weight Reduction, Exercise, And Diet Modification On Lipids And Apolipoproteins A-L And B In Severely Obese Persons, J. David Fachnie, Craig C. Foreback

Henry Ford Hospital Medical Journal

We assessed the lipid and apolipoprotein effects of hypocaloric dieting, increased physical activity, and dietary modification in severely overweight adults (body mass index [BMI] 43.05 kg/m-). The 34 women and four men enrolled in the ambulatory weight control program donated blood before, during, and after hypocaloric dieting (420 kcal/day). Mean values before dieting included cholesterol of 223 mg/dL, high-density lipoprotein (HDL) cholesterol of 43 mg/dL, and cholesterol/HDL cholesterol of 5.90. This placed our subjects at high risk for coronary artery disease. Other values included triglycerides of 138 mg/dL, apolipoprotein A-l of 152 mg/dL. and apolipoprotein B/apolipoprotein A-l of 0.64. Significant …

Management Of Extramedullary Plasmacytomas, James A. Bonner, Jadranka Dragovic, Michael P. Abrash

Henry Ford Hospital Medical Journal

From 1965 through 1982. 12 patients with solitary, biopsy-proven extramedullary plasmacytomas (EMPs) were treated at our institution with surgery alone or biopsy followed by radiation therapy. The median age of the patients was 67 years, and the median-follow-up was 58 months. Of the seven patients who were treated by primary surgery, three developed recurrent or distant disease. Five patients underwent biopsy followed by radiation therapy, and none of their tumors progressed. Our series and a review of the literature show that occasionally EMPs will incompletely regress even after high doses of radiation (greater than 65 Gy); however, we recommend that …

Unusual Lymphomas Developing In Chronic Lymphocytic Leukemia, Sundara B. K. Raman, Sheikh M. Saeed, Joseph P. Abraham

Henry Ford Hospital Medical Journal

We report three patients with chronic lymphocytic leukemia (CLL) who developed malignant lymphomas of unusual character and modes of presentation. Two of the patients had received low doses of chlorambucil for several years before they developed malignant lymphoma, diffuse, large cell type (LCL). In one of these patients LCL manifested as a grossly evident osteolytic lesion. In the second patient LCL developed initially as a localized lesion in the iliac bone. Both patients died within a few weeks after LCL was diagnosed. The third patient, who was found to have CLL during a routine examination, did not receive any therapy …

T-Cell Lymphoma In Renal Transplant Recipient, Koichi Maeda, Leslie Bricker, Chan K. Ma, Michael J. Deegan

Henry Ford Hospital Medical Journal

A 35-year-old woman, who had a renal transplant flve years ago, developed malignant lymphoma of the mediastinum. The lymphoma was of lymphoblastic type and had T-cell immunophenotype. Most transplant-related lymphomas are of B-cell type. T-cell lymphoma in this setting is extremely rare, and the mechanism of development may be different from that of B-cell lymphomas.

Obstructing Giant Pseudopolyposis Of The Colon In Ulcerative Colitis, Roberta E. Sonnino, Farouck N. Obeid

Henry Ford Hospital Medical Journal

Pseudopolyposis of the colon is a well-recognized local complication of ulcerative colitis. Giant pseudopolyposis is uncommon, and its presentation as a complete obstruction of the colon is a rare occurrence. We report such a case, where retrograde flow of barium on double-contrast barium enema was completely obstructed at midtransverse colon. After resection by total abdominal colectomy, pathology examination ofthe specimen confirmed massive pseudopolyposis without malignancy. A brief review of the pathology and current literature is presented.

The Aids Project Newsletter (October 1987), David Ketchum, The Aids Project

AIDS Project Newsletter (1987-1991)

No abstract provided.

Tardive Dyskinesia: A Prevalence Study In An Outpatient Population, Virginia J. Ravizza

Community & Environmental Health Theses & Dissertations

The purpose of this prevalence study was to assess the occurrence of tardive dyskinesia among a chronically mentally ill sample of a suburban mental health clinic. The participants in this study were selected from clients of a suburban mental health clinic who agreed to participate in this prevalence study. There were 45 participants--17 males and 28 females.

The Abnormal Involuntary Movement Scale (AIMS) was selected as the instrument to measure the abnormal involuntary movements exhibited by the participants of the study on the day of testing. The testing occurred during a specific time period, June 8, 1987 to July 2, …

Commencement Program 1987 (Summer Conferring Of Degrees), Loma Linda University

Commencement Programs

CONTENTS

3 | The Academic Procession

4 | Conferring of Degrees

6 | Candidates for Degrees

Effects Of Dietary Calcium Levels On Human Blood Pressures, Janice Mearkle

Masters Theses & Specialist Projects

The prevalence of hypertension in the U.S. and similar industrialized countries continues to rise. Millions of people are affected in America alone. Usual treatment includes a low sodium diet, weight loss if needed, and drug therapy. Some health providers also encourage stress management as an adjunct to therapy. These treatments have been shown to be effective but patient compliance continues to be poor. Past research has explored the relationships between dietary calcium and hypertension and has found that there is an interaction between blood calcium levels and high blood pressure. The research reported here was a test of the relationship …

Thyroid C-Cell Hyperplasia And Micronodules In Close Relatives Of Men-2 A Patients: Pitfalls In Early Diagnosis And Reevaluation Of Criteria For Surgery, Cees J. M. Lips, John R. Leo, Marianne J. H. Berends, Werner H. Minder, A. P. Roeland Blok, Rolf A. Geerdink, Wil H. L. Hackeng, Jan M. M. Roelofs, Hans F. A. Vasen, Jan K. Vette

Henry Ford Hospital Medical Journal

In a large family with multiple endocrine neoplasia rype 2 A (MEN-2 A), 20 patients were identified by the diagnosis of medullary thyroid carcinoma (MTC) and/or pheochromocytomas. Another five subjects had neck surgery on the basis of slightly increased results of a C-cell provocative test. Retrospectively, however, although the immunohistochemical diagnosis of C-cell hyperplasia was confirmed, the diagnosis of MEN-2 was doubtful in these five subjects, and the C-cell hyperplasia observed was probably within the limits of normal variation. The occurrence of C-cell hyperplasia in a normal population was investigated by a C-cell provocative test, as well as in random …

The Aids Project Newsletter (July 1987), David Ketchum, The Aids Project

AIDS Project Newsletter (1987-1991)

No abstract provided.

Reactions Of Organic N-Chloramines In The Gastric Fluid Of The Rat, Kathryn E. Mazina

Chemistry & Biochemistry Theses & Dissertations

Using chlorine as a drinking water disinfectant may have potential health effects due to its reactivity with organic amino nitrogen compounds found in the stomach. Organic N-chloramines have been shown to form in the stomachs of laboratory rats. The possible reactions of N-chloramines in the stomach fluid were examined in this study using a model radiolabeled N-chloramine. ³⁶Cl-N-Chloropiperidine, was synthesized and purified to remove ³⁶Cl-chloride. Stomach fluid was obtained from Sprague-Dawley rats which had been first fasted for 24 or 48 hours and then administered 3 mL of deionized water. Different concentrations of radiolabeled chloramine were reacted with …

One Large Kindred Excludes A Locus For Multiple Endocrine Neoplasia Type 2a From About 25% Of The Human Autosomal Genetic Map, Andrew J. Pakstis, Judith R. Kidd, Carmela M. Castiglione, Beth A. Pletcher, Patricia D. Murphy, Lindsay A. Farrer, Myron Genel, Kenneth K. Kidd

Henry Ford Hospital Medical Journal

This report presents pairwise linkage results from our search for the locus of the gene (MEN2A) for the multiple endocrine neoplasia type 2A (MEN-2A) syndrome in one large kindred (the N kindred), clearly segregating for an autosomal dominant form. About 25% of the autosomal genome is excluded when these new results are combined with those we have published previously. The genetic markers employed are distributed across at least 19 of the 22 autosomes. Seven genetic markers whose chromosomal locations are not yet established have also been studied.

Screening For Early Asymptomatic Pheochromocytoma In Men-2, Margareta Telenius-Berg, Bertel Berg, Bertil Hamberger, Sten Tibblin

Henry Ford Hospital Medical Journal

Pheochromocytoma is a major cause of morbidity in multiple endocrine neoplasia type 2. We recommend a similar diagnostic screening approach for early asymptomatic pheochromocytoma as is generally accepted for asymptomatic medullary thyroid carcinoma. We present a new provocative test for early asymptomatic pheochromocytoma. Plasma epinephrine levels and epinephrine/dopamine ratios after physical exercise seem to have higher sensitivity than basal plasma catecholamine levels. Specificity is high especially for discrimination from neurovegetative lability, which is the clinically most important differential diagnosis.

The Mexican American Elderly And Barriers To The Utilization Of Health Care Services, Kathleen Anne Hoekstra

Masters Theses

The utilization of health care services by the Mexican American elderly is low compared to the severity of their health problems. This thesis examines the sociocultural factors which affect the interaction of the Mexican American elderly and mainstream health professionals. Included is a brief history detailing discriminatory practices, a description of traditional Mexican cultural practices and attitudes, and an exploration of the cultural barriers which limit access to health care.

Commencement Program 1987, Loma Linda University

Commencement Programs

CONTENTS

2 | 1987 Events of Commencement

3 | Academic Procession

4 | The Speakers

7 | The Honorees

Order of Programs

• School of Dentistry, 12
• School of Medicine, 18
• Graduate School, 24
• School of Nursing, 29
• College of Arts and Sciences, School of Business and Management, and School of Education, 33
• School of Allied Health Professions, 44
• School of Health, 49

Case-Control Study Of Vitamin A Intake And Colorectal Cancer In Seventh-Day Adventists, John William Morgan

Loma Linda University Electronic Theses, Dissertations & Projects

Colorectal cancer is the second most common cause of cancer deaths in Americans; producing approximately 60,000 deaths in Americans each year. Studies of high and low risk populations have suggested a dietary etiology for colorectal cancer, although investigations of specific dietary factors have produced inconsistent results.

Population based studies of California Seventh-day Adventists demonstrate dietary variety regarding factors suspected as important in the etiology of colorectal cancer. These studies document a substantially reduced mortality and incidence from colorectal cancer in Seventh-day Adventists when compared to other California Populations. Although specific reasons for this difference remain obscure, the 'Unique lifestyle and …

Evaluating The Effect Of Family Stroke Education On The Anxiety Levels Of Families Of Stroke Patients, Keri Lynne Kuniyoshi

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

Health Care Policy Issues Related To Aids: Lessons Learned From The Henry Ford Hospital Experience, David W. Benfer

Henry Ford Hospital Medical Journal

No abstract provided.

The Clinicians' Guide To Creutzfeldt-Jakob Disease, Thomas H. Swanson

Henry Ford Hospital Medical Journal

Creutzfeldt-Jakob disease, a transmissible, rapidly progressive dementia of unknown etiology, mimics Alzheimer's disease, presents in middle life, and affects many central nervous system structures. The disease progresses in three distinct stages, culminating in death. Its occurrence is sporadic and its distribution worldwide. Pathological changes are varied, but spongy degeneration of the neuropil is classic. Research on scrapie, the animal model of Creutzfeldt-Jakob disease, has demonstrated that this unconventional, slow disease is transmitted via a small (less than 50,000 mW) particle, which is composed principally of protein. How this infectious particle, variably named prion, virino, or slow virus, invokes disease or …

Renal Involvement In The Acquired Immunodeficiency Syndrome: Presentation, Clinical Course, And Therapy, Robert Provenzano, Warren Kupin, Godofredo C. Santiago

Henry Ford Hospital Medical Journal

Acute renal failure developing during the clinical course of the acquired immunodeficiency syndrome (AIDS) has been related to complications of sepsis, nephrotoxic antibiotics, and recently to the development of glomerular lesions. Of 114 AIDS patients admitted to our hospital between January 1985 and June 1986. II patients (9.6%) developed acute renal failure. None of these II patients had a history of intravenous drug abuse or hypertension. All patients were male with an average age of 35 years old, 81% were black, and all were bisexual or homosexual. Renal failure was attributed to AIDS-related focal glomerulosclerosis (five cases), prerenal azotemia (one …

Aids Update, Evelyn J. Fisher

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Neurologic Complications Of The Acquired Immunodeficiency Syndrome, Stuart N. Kieran

Henry Ford Hospital Medical Journal

No abstract provided.

The Aids Challenge: A Psychosocial Perspective, Madelyn S. Plotkin, Margaret Dietz Domanski

Henry Ford Hospital Medical Journal

No abstract provided.

Bilateral Anterior Cerebral Artery Occlusion In An Alcohol Abuser With Sickle-Cell Trait, Thomas H. Swanson, John L. Zinkel, Patti L. Peterson

Henry Ford Hospital Medical Journal

The contribution of ethanol ingestion to brain infarction is unclear, although many studies suggest that the two may be causally related. We report an unusual case of bilateral anterior cerebral artery occlusion in a young female ethanol abuser with sickle-cell trait whose platelets showed hyperaggregability during epinephrine and adenosine diphosphate-induced aggregation experiments. It is concluded that ethanol withdrawal and dehydration along with direct effects of ethanol on platelet aggregation may result in cerebral artery thrombosis. Sickling of red blood cells in the distal circulation also may be a compounding factor, but this is not proven.

Biotechnology In The Conquest Of Infectious Diseases, Ashley T. Haase

Journal of the Minnesota Academy of Science

No abstract provided.

A Study Of The Relationship Between Golf Performance And Depth Perception, Arm/Hand Steadiness, Grip Strength And Dynamic Balance, Charles W. Ruot

Masters Theses

No abstract provided.

The Variability Of Heart Rate Response To A Submaximal Bicycle Test Given On Three Consecutive Days, Jacqueline Marie Dacey

Masters Theses

No abstract provided.

The Effect Of Regular Aerobic Exercise On Cholesterol And Triglyceride Values In An Adult Population, Lisa Einheuser

Masters Theses

No abstract provided.

Forest Conservation In Nepal: Encouraging Women's Participation, Augusta Molnar

Poverty, Gender, and Youth

This issue of SEEDS focuses on ways in which women have been involved in a government forest conservation and restoration program in Nepal. As is common with many large-scale projects with a general impact, women were not a direct focus of the project's original design. As activities got underway, however, both the Nepali staff and their expatriate colleagues quickly realized that the direct involvement of women was crucial to the success of the project's participatory strategy. Over the initial five years, 1980 to 1985, a number of approaches to addressing women's needs and generating their active participation were tried. The …