Digital Commons Network^™

The Emergence Of Systematic Review In Toxicology, Martin L. Stephens, Kellyn Betts, Nancy Beck, Vincent Cogliano, Kay Dickersin, George Gray, +8 Additional Authors

Environmental and Occupational Health Faculty Publications

The Evidence-based Toxicology Collaboration hosted a workshop on “The Emergence of Systematic Review and Related Evidence-based Approaches in Toxicology,” on November 21, 2014 in Baltimore, Maryland. The workshop featured speakers from agencies and organizations applying systematic review approaches to questions in toxicology, speakers with experience in conducting systematic reviews in medicine and healthcare, and stakeholders in industry, government, academia, and non-governmental organizations. Based on the workshop presentations and discussion, here we address the state of systematic review methods in toxicology, historical antecedents in both medicine and toxicology, challenges to the translation of systematic review from medicine to toxicology, and thoughts …

Leveling The Playing Field Through Partnerships And Collaboration : Neighborhood Revitalizations And The Influence Of Social Determinants Of Health And Institutional Logics., J. M. Bohn

Electronic Theses and Dissertations

A qualitative study guided by grounded theory was on a Midwest US city (population > 50,000 people), three of its inner city neighborhoods, and community coalition and partnership efforts in neighborhood revitalizations. A two-phase semi-structured interview methodology assessed interviewees’ experiences in initiatives focused on improving social determinants of health in the neighborhoods. Phase I interviews (n= 11) identified the spectrum of partnerships and initiatives while Phase II interviews (n=28) captured detailed experiences of interviewees. Inter-institutional systems and institutional logics theory were applied in the post-data collection analysis. Interviewees were from public and private sectors including: built environment, economic development, residential/commercial property …

The Influence Of Nutrition Education And Self-Efficacy On Fruit And Vegetable Consumption For Low-Income Women In Rural West Kentucky., Lewatis Darnell Mcneal

Electronic Theses and Dissertations

Objective: To examine how participation in nutrition education programs, self-efficacy to consume fruit and vegetables and predictor of behavior to eat health foods (POB) influences the consumption of fruit and vegetables for low-income women in west Kentucky eligible or participating in federal supplemental nutrition assistance programs. Methods: A comparative study was conducted between low-income women participating in Special Supplemental Nutrition Assistant Program for Women and Children (WIC) and those eligible for SNAP but were not participating. The study examined consumption in six categories of fruit and vegetables, self-efficacy to consume fruit and vegetables, predictor of behavior to eat healthy foods …

The Impact Of Medicaid Expansion On Utilization Of Mental Health Services In West Louisville, Kentucky., Susan Theresa Buchino

Electronic Theses and Dissertations

Mental health is an essential component of overall health status, and mental illnesses are a leading cause of disability. In addition to expanding insurance coverage, the Affordable Care Act (ACA) reinforced parity for mental health services in insurance plans. This mixed-methods study assessed mental health service utilization by an urban and predominately African-American population following the successful implementation of the ACA and Medicaid expansion in Louisville, KY. Claims data from one Medicaid Managed Care Organization were analyzed to assess mental health care utilization patterns pre- and post- Medicaid expansion and determine differences in utilization rates between the Medicaid expansion population …

An Evaluation Of College Students’ Use Of Social Media In Nutrition Education For Lifestyle Behavior Changes, Cassandra Crawford-Ciglar

All Theses And Dissertations

Behavior change is a process. College students routinely have poor eating habits during a time of life that can negatively impact health outcomes for the adult years. While knowledge of nutrition is essential to promote health and wellness, other components are required to change behavior. Specifically, nutrition education must be paired with behavior change skills or goal setting strategies in order for a change to occur. In a college classroom setting, many examples of such strategies already exist. Literature supports evidence that interventions combining social media and behavior change techniques incorporating online social networks may be effective. The purpose of …

Breastfeeding Rates In Marshallese Mothers; A Needs Assessment, Olivia N. Pennington

The Eleanor Mann School of Nursing Undergraduate Honors Theses

ABSTRACT

Background. Multiple health disparities are associated with the Marshallese population in Northwest Arkansas. Childhood obesity, linked to a decrease in exclusive breastfeeding, is one of the predominant issues. Since their migration to the United States, exclusive breastfeeding rates of Marshallese mothers have steadily declined throughout the years. Little research has been conducted to help combat this growing health disparity. Due to the increased growth in this population in Northwest Arkansas, it is imperative that measures are taken to decrease these disparities to improve the overall health of the future generations.

Objective: To determine the relationship between maternal age, …

Effects Of An Educational Intervention On Exclusive Breastfeeding Rates In Marshallese Mothers Residing In The U.S., Bentley S. Snider

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Abstract

Background: The Marshallese are one of the fastest growing migrant populations in the U.S. They have considerable health disparities despite their increasing access to health care. The Marshallese women in this population prefer to breastfeed, but have encountered many cultural barriers that have deterred them from exclusively breastfeeding for a significant amount of time. Breastfeeding is linked to many protective benefits for children’s health, such as decreasing the likelihood of obesity, even into the adult years.

Objective: The purpose was to evaluate the impact on breastfeeding rates through implementation of a culturally significant educational intervention for the …

The National Diabetes Prevention Program An Intervention For Diabetes Risk Reduction, Kavita Batra

UNLV Theses, Dissertations, Professional Papers, and Capstones

Diabetes mellitus is among the most frequently occurring chronic conditions, affecting 28 million adults in the Nation. The Nevada diabetes prevalence rate is approaching the National average, with 1 out of 4 diabetic patients experiencing serious clinical complications. Diabetes is typically preceded by a preventable condition classified as prediabetes, in which the blood sugar level exceeds the normal level, yet not enough to be classified as Type 2 diabetes. Prediabetes increases the risk of developing diabetes within 10 years, if not effectively managed. In an attempt to help reduce this risk, the CDC recently introduced an evidence-based intervention, the National …

Impacts To Phytoplankton After The Establishment Of Quagga Mussels In Lake Mead, Nevada, Warren Bruce Turkett

UNLV Theses, Dissertations, Professional Papers, and Capstones

Quagga mussels (Dreissena rostriformis bugensis) are an invasive species that were discovered in Lake Mead in January of 2007, and rapidly spread throughout the lake. Quagga mussels are about the size of a fingernail, but are known to clog pipes, damage infrastructure and alter ecosystems. In large numbers, mussels can have a dramatic impact on an ecosystem by reducing the phytoplankton and potentially increasing toxin producing cyanobacteria. This research analyzed data collected from three separate basins in Lake Mead to determine if water quality characteristics that are commonly impacted by invasive mussels have changed. Transparency, chlorophyll-a, phytoplankton and zooplankton samples …

The Effect Of The Expanded Food And Nutrition Education Program On Participants’ Diet Quality: Does Supermarket Access Matter?, Rachel Ann Spencer

Graduate Theses and Dissertations

This project assesses the effectiveness of the Expanded Food and Nutrition Education Program (EFNEP) within the context of supermarket access. EFNEP is a national community nutrition education program that strives to give participants the tools to live healthier lives. Analysis was performed on participants from 16 Arkansas counties that completed EFNEP during 2013 or 2014. The program outcome is measured in terms of the change in Healthy Eating Index (HEI) as calculated from 24-hour diet recalls at program entry and exit. Supermarket locations were obtained from the USDA Food Nutrition Service’s SNAP Retail Locator and represent the food environment near …

Implementing A Good Catch Program In Nursing Homes, Leigh Raposo

Muskie School Capstones and Dissertations

Rationale and processes for reporting near misses and evidence-based tools were collected by a literature search, seminal works by Sidney Dekker and James Reason, and websites for the Agency for Healthcare Research and Quality (AHRQ), the Institute for Healthcare Improvement (IHI), and the Centers for Medicare and Medicaid Services (CMS). Tools, information, and strategies found in this research were evaluated for implementation in Maine nursing homes. The tools provide a communication vehicle for nursing home staff to safely report to management near misses, or mistakes that do not harm residents. To emphasize a positive approach, the project replaces the term …

Short-Term Outcome Evaluation Of Healthy Habits, Healthy U: A School-Based Cancer Prevention Program, Alicia Anderson

Boise State University Theses and Dissertations

Healthy Habits, Healthy U (HHHU) is a school-based cancer prevention program. This program is a collaborative effort among Boise State University, St. Luke’s Mountain States Tumor Institute, and the Boise School District. HHHU started in April 2013 as a community outreach initiative designed to teach and reinforce positive health habits in students. HHHU lessons target eighth-grade students and offer a unique approach highlighting the relationships among nutrition, physical activity, sugar-sweetened beverages, and cancer risks, through a variety of educational materials.

The purpose of this study was to assess program efficacy by evaluating short-term outcomes. The study evaluated the effectiveness of …

Biosand Water Filter Evaluation: Meta-Evaluation And Pilot Study Of Field Use Indicators, Bethesda O'Connell

Electronic Theses and Dissertations

Diarrheal diseases are a global public health burden, killing 1.8 million people annually. Diarrhea disproportionately affects children and those in poverty. Most diarrheal cases can be prevented through safe drinking water, basic hygiene and/or sanitation measures, with drinking water interventions having the most impact on reducing diarrheal disease. A meta-evaluation was completed of studies evaluating a specific household water treatment method, the biosand water filter. Results from the meta-evaluation illustrate that biosand water filters improve drinking water quality and reduce diarrheal disease. However, there is no generally agreed upon field method for determining biosand water filter effectiveness that is useable …

Doulas Could Improve Foreign-Born Women’S Perinatal And Postpartum Satisfaction And Increase Health Providers’ Cultural Competency In A Multicultural Urban Area Of The United States., Crystal Kazik

Sustainability and Social Justice

Doulas act as a cultural bridge between clients and providers through the support, advocacy, and education they provide. Unfortunately, migrant women may be at a disadvantage for accessing and benefiting from their services due to a variety of socioeconomic and cultural factors including predisposed ideas of care and structure based on experiences in native countries, language barriers, lower health literacy, and a lack of awareness and understanding from hospital/clinic staff.

A strategic multifaceted approach utilizing doulas, such as Boston Medical Center’s collaborative and culturally competent model, may greatly improve foreign-born women’s experience and satisfaction with healthcare when pregnant and giving …

An Evaluation Of Factors Which Can Affect The Implementation Of A Health Promotion Programme Under The Schools For Health In Europe Framework, Annemarie Bennett, Cara Cunningham, Charlotte Johnston Molloy

Articles

The Health Promoting Schools concept helps schools to promote health in a sustainable and long-term fashion. However, developing the capacity to promote health in this way can be challenging when a busy teaching curriculum must be fulfilled. This study aimed to identify factors which affect the acceptability of health promotion programmes to the everyday school environment.

Semi-structured qualitative interviews were audio-taped with primary school teachers in one Irish county and transcribed verbatim. The resulting transcripts were analysed using content analysis.

Thirty-one teachers were interviewed. The factors which may adversely affect the acceptability of health promotion programmes include the: attitude of …

Assessing The Role Of Faith-Based Organizations In Health Promotion, Troylyn Braud Francis

Theses and Dissertations (ETD)

Objective: The objective of this analysis was to evaluate the relationship between organizational readiness (OR) and weight loss and physical activity outcomes among faith-based organizations (FBOs).

Methods: Data for this study were collected in two phases. Phase I data were based on a feasibility study and targeted African-American individuals (N = 55) who participated in an obesity prevention program. The intervention was accomplished in two stages, which included a 10-week core period followed by a 6-month maintenance period. Phase II data were based on key informant interviews that were conducted with community health leaders (CHLs) (N=6) from participating …

Stop Stunting: Situation And Way Forward To Improve Maternal, Child And Adolescent Nutrition In Afghanistan, Ariel Higgins Steele, Piyali Mustaphi, Sherin Varkey, Humayoun Ludin, Najibullah Safi, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

No abstract provided.

Beyond The Millennium Development Goals: An Evaluation Of The War On Hiv / Aids In Kenya, Robert G. Nyaga

Theses and Dissertations

HIV/AIDS remains a threat to Kenya and other developing nations. This thesis aimed at assessing the HIV/AIDS situation in Kenya by examining the knowledge of Kenyans towards infection and spread HIV/AIDS, attitudes towards people living with HIV/AIDS, involvement of community opinion leaders in the HIV/AIDS campaigns, sharing of HIV/AIDS information, and government efforts to control HIV/AIDS. A sample of Kenyans (N= 103) was surveyed and asked to respond to several scales assessing each of the above items. Quantitative and qualitative methods reveal the knowledge and attitudes portrayed by Kenyans and show that, although much has been achieved, there is need …

Health Behaviors And Their Correlates Among Participants In The Continuing To Confront Copd International Patient Survey, Hana Müllerová, Sarah H. Landis, Zaurbek Aisanov, Kourtney J. Davis, Masakazu Ichinose, David M. Mannino, Joe Maskell, Ana M. Menezes, Thys Van Der Molen, Yeon-Mok Oh, Maggie Tabberer, Meilan K. Han

Preventive Medicine and Environmental Health Faculty Publications

Background and aims: We used data from the Continuing to Confront COPD International Patient Survey to test the hypothesis that patients with COPD who report less engagement with their disease management are also more likely to report greater impact of the disease.

Methods: This was a population-based, cross-sectional survey of 4,343 subjects aged ≥ 40 years from 12 countries, fulfilling a case definition of COPD based on self-reported physician diagnosis or symptomatology. The impact of COPD was measured with COPD Assessment Test, modified Medical Research Council Dyspnea Scale, and hospital admissions and emergency department visits for COPD in the prior …

Network-Driven Plasma Proteomics Expose Molecular Changes In The Alzheimer's Brain, Philipp A. Jaeger, Kurt M. Lucin, Markus Britschgi, Badri Vardarajan, Ruo-Pan Huang, Elizabeth D. Kirby, Rachelle Abbey, Bradley F. Boeve, Adam L. Boxer, Lindsay A. Farrer, Nicole Finch, Neill R. Graff-Radford, Elizabeth Head, Matan Hofree, Ruochun Huang, Hudson Johns, Anna Karydas, David S. Knopman, Andrey Loboda, Eliezer Masliah, Ramya Narasimhan, Ronald C. Petersen, Alexei Podtelezhnikov, Suraj Pradhan, Rosa Rademakers, Chung-Huan Sun, Steven G. Younkin, Bruce L. Miller, Trey Ideker, Tony Wyss-Coray

Pharmacology and Nutritional Sciences Faculty Publications

Background: Biological pathways that significantly contribute to sporadic Alzheimer’s disease are largely unknown and cannot be observed directly. Cognitive symptoms appear only decades after the molecular disease onset, further complicating analyses. As a consequence, molecular research is often restricted to late-stage post-mortem studies of brain tissue. However, the disease process is expected to trigger numerous cellular signaling pathways and modulate the local and systemic environment, and resulting changes in secreted signaling molecules carry information about otherwise inaccessible pathological processes.

Results: To access this information we probed relative levels of close to 600 secreted signaling proteins from patients’ blood samples using …

Aberrant Dna Methylation: Implications In Racial Health Disparity, Xuefeng Wang, Ping Ji, Yuanhao Zhang, Joseph F. Lacomb, Xinyu Tian, Ellen Li, Jennie L. Williams

Department of Biomedical Engineering Faculty Publications

Background Incidence and mortality rates of colorectal carcinoma (CRC) are higher in African Americans (AAs) than in Caucasian Americans (CAs). Deficient micronutrient intake due to dietary restrictions in racial/ethnic populations can alter genetic and molecular profiles leading to dysregulated methylation patterns and the inheritance of somatic to germline mutations. Materials and Methods Total DNA and RNA samples of paired tumor and adjacent normal colon tissues were prepared from AA and CA CRC specimens. Reduced Representation Bisulfite Sequencing (RRBS) and RNA sequencing were employed to evaluate total genome methylation of 5’-regulatory regions and dysregulation of gene expression, respectively. Robust analysis was …

Breastfeeding Education For Fathers: An Intervention To Increase Breastfeeding Rates, Jill Marie Frisz

Evidence-Based Practice Project Reports

If every infant were breastfed within an hour of birth, exclusively breastfed until six months, and given breastmilk up to two years, almost 800,000 lives would be saved annually (who, 2014). Nationally, breastfeeding rates drop significantly from three to six months. A search of literature yielded significant evidence as fathers for facilitators to increase breastfeeding rates. The purpose of this evidence based practice (EBP) project was to determine the effects of best practice measures to educate fathers about breastfeeding to increase anytime breastfeeding rates. The social support theory and ACE Star model guided the literature search and implementation of this …

Geographic Distribution Of Maternal Group B Streptococcus Colonization And Infant Death During Birth Hospitalization: Eastern Wisconsin, Jessica J. F. Kram, Dennis J. Baumgardner, Kiley B. Vander Wyst, Melissa A. Lemke

Journal of Patient-Centered Research and Reviews

Purpose

Maternal group B Streptococcus (GBS) can be transmitted from a colonized mother to newborn during vaginal delivery and may or may not contribute to infant death. This study aimed to explore the geographic distribution and risk factors of maternal GBS colonization and infant death during birth hospitalization.

Methods

We retrospectively studied mothers with live birth(s) in a large eastern Wisconsin hospital system from 2007 through 2013. Associations between maternal and neonatal variables, GBS colonization and infant death were examined using chi-squared, Mann-Whitney U and t-tests. Multivariable logistic regression models also were developed.

Results

Study population (N = 99,305) had …

Improving The State Of Health Literacy Among American Adults: Why Community Outreach Methods Are More Effective Than Literacy-Level Screenings, Lydia Simpson

Honors Theses

Health literacy refers to an individual’s ability to access and process health information to make important decisions about their health. Unfortunately, millions of American adults have inadequate health literacy skills and are not able to navigate their way through the world of health care. This may lead to disastrous consequences and poor health outcomes. To improve health literacy, nationwide health education programs are imperative. Despite this, low health literacy is often ignored, or only considered for individuals suspected of having low health literacy who might then be administered a screening instrument. A better model for the American health care system …

Associations Of Birth Order With Early Adolescent Growth, Pubertal Onset, Blood Pressure And Size: Evidence From Hong Kong’S “Children Of 1997” Birth Cohort, Man Ki Kwok, Gabriel M. Leung, C. Mary Schooling

Publications and Research

Background: Birth order has been proposed as a cardiovascular risk factor, because the lower birth weight and greater infant weight gain typical of firstborns could programme metabolism detrimentally.

Methods: We examined the associations of birth order (firstborn or laterborn) with birth weight-for-gestational age, length/height and body mass index (BMI) z-scores during infancy, childhood, and puberty using generalized estimating equations, with age at pubertal onset using interval- censored regression and with age-, sex- and height-standardized blood pressure, height and BMI z-scores at 13 years using linear regression in a population-representative Chinese birth cohort: “Children of 1997” (n = 8,327).

Results: Compared …

Continuum Of A Declining Trend In Correct Self-Perception Of Body Weight Among American Adults, Amber Morgan

GS4 Student Scholars Symposium

Background: Over the past few decades, the prevalence of obesity in the United States has steadily increased with the proportion of obese Americans projected to be about fifty percent in 2030. With more than half of adults being overweight or obese (OW/OB), an increasing number of adults failed to accurately perceive body weight, which may be a major barrier to weight loss strategies, thus, presenting a substantial challenge to prevention efforts. The objective of this study was to assess the dynamic trend of body weight related self-perception among American adults and provide recommendations for improving obesity prevention strategies.

Methods …

Effects Of Serum Levels Of Vitamin A And Precursors On Colorectal Cancer Mortlaity, Chimuanya Okoli

GS4 Student Scholars Symposium

Objective: To examine the relationship between serum levels of Vitamin A and precursors on Colorectal cancer mortality. Methods: A retrospective cohort study was conducted with 14,358 adults who participated in NHANES III. Data was collected via in home interviews and visits by participants to a mobile examination centre for blood sample collection. Characteristics such as family income, educational attainment, marital status, race and ethnicity, alcohol consumption, cigarette smoking, self reported health, type of resident, body size, cancer status at base line, vegetable consumption and fruit juice consumption were examined. Hazard ratio estimates for all-cause and cancer-related deaths among individuals with …

Association Between Fruit And Vegetable Consumption And Sleep Quantity In Pregnant Women, Kassandra Snook

GS4 Student Scholars Symposium

The National Sleep Foundation recommends an average sleep time duration of 7-9 hours per day for adults aged 18-64 years old. Unfortunately, women are prone to encounter sleep disruptions during pregnancy that can prevent them from the recommended amount of sleep. Poor sleep during pregnancy is associated with an increased risk for birth complications, including low birth weight and stillbirth. Studies have found that sleeping less and poor sleep quality is associated with lower consumption of fruits and vegetables and good sleep quality/adequate sleep is associated with increased fruit and vegetable consumption. The objective of this study was to determine …

The Impact Of A Nutrition Education Intervention On Self-Reported Feelings Of Food Insecurity, Caitlin Koch

GS4 Student Scholars Symposium

Abstract Unavailable

The Presence Of Stem Cells In Human Breast Milk And Research Implications, Melody (Brooke) Peterson

Senior Honors Theses

Stem cell therapy research is an expanding area of study as stem cell therapy is believed to have the potential to provide treatment options for numerous disease processes. Currently, embryonic stem cell research is the method of choice to evaluate the potential for stem cell therapy. The use of human embryos for stem cell research raises moral and ethical controversies. Stem cells are found in a variety of mediums, but until the recent discovery of stem cells in human breast milk, the most versatile stem cells have been those found in the human embryo. Human breast milk stem cells could …