Digital Commons Network^™

Review Of Cancer Among Indigenous Peoples, Sasha Stumpers, Neil Thomson

Research outputs pre 2011

This review provides a comprehensive synthesis of population-level cancer statistics and other key information for Aboriginal and Torres Strait Islander people alongside comparative figures for non-Indigenous Australians. It includes general information on the extent of cancer, including: incidence, hospitalisation and mortality. The review also provides information on the extent of cancer for specific cancers: lung, cervical, breast, prostate, liver, pancreatic and colorectal (bowel). Finally, the review discusses issues surrounding Aboriginal and Torres Strait Islander people’s use of cancer services.

Public Water Fluoridation, Jessica Fohey

Honors Program Theses

This thesis project addresses the issue of public water fluoridation. There is a debate within the United States as to whether or not public water systems should be fluoridated. Because of the large scale potential health impact, it is critical to determine whether or not this practice is in the best interest of the public. This paper provides an extensive review of scientific literature on the effectiveness, safety, and cost effectiveness of public water fluoridation. Following the review of scientific literature, I will present an overview of pseudo-scientific literature which advocates against public water fluoridation that, although often not scientifically …

Implications For Nursing Practice: Delivering The Folic Acid Message, Kimberly Townsend Little

UNLV Theses, Dissertations, Professional Papers, and Capstones

In 1995, North Carolina (NC) had one of the highest prevalence rates of neural tube defects (NTDs) in the United States. Since the NC Folic Acid Council began focusing their efforts on educating women of childbearing age regarding NTDs in 1994, the prevalence of NTDs has declined overall by 40%; however, NTD prevalence among Hispanics in NC continues to be double the rate of non-Hispanics. Research has found daily consumption of a multivitamin with folic acid significantly decreases NTDs. Healthy People 2010 include in their objectives the need to increase folic acid consumption in women and reduce the NTD rates. …

Prenatal Physical Activity Patterns And Determinants In An Urban Ecuadorian Population, Erika Gonzalez Beltran

Open Access Theses & Dissertations

Background & Significance. Evidence has accumulated over the past two decades suggesting that healthy pregnant women who engage in regular moderate physical activity (PA) may reduce their risk for certain adverse pregnancy and postnatal health outcomes. The U.S. Department of Health and Human Services (DHHS)/Centers for Disease Control and Prevention (CDC) recently issued the 2008 Physical Activity Guidelines for Americans which recommends at least 150 minutes/week of moderate-intensity aerobic PA for pregnant women. The American College of Obstetricians and Gynecologists (ACOG, 2002) recommends 30 min of moderate-intensity PA, specified as derived from recreational or leisure activities on most or all …

Project L.E.A.N.: An After-School Health And Exercise Project For Elementary School Children In El Paso, Texas, Hendrik De Heer

Open Access Theses & Dissertations

INTRODUCTION: After-school activities provide valuable opportunities for health promotion activities that do not interfere with the regular school day, especially in minority populations with higher rates of obesity and type 2 diabetes. The current study is an evaluation of an after-school health education and physical activity program conducted in nine elementary schools in 2008 in El Paso, Texas. METHODS: The intervention consisted of a 10-12 week (twice a week) after school program consisting of a pilot (with two experimental schools) and main intervention (six schools each including a control and experimental group). The main outcome variables were Body Mass Index, …

Social Support, Weight Loss Attempts And Satisfaction, Allison Drew

Theses and Dissertations

Objective: The purpose of this study was to determine the extent to which the presence of social support correlates with attempts at weight loss in the past 12 months, attempts not to gain weight in the past 12 months, and participants’ satisfaction with their weight status. Methods: We used a cross-sectional study design using data collected by the 2003-2004 and 2005-2006 National Health and Nutrition Examination Surveys (NHANES) (CDC). For this study we included males and females, of multiple ethnicities, and a range of ages from 40 to 70 + years. Participants with missing data on height and weight were …

Gender Specific Differences In The Pros And Cons Of Smoking Among Current Smokers In Eastern Kentucky: Implications For Future Smoking Cessation Interventions, Dana A. Hazen, David M. Mannino, Richard Clayton

Preventive Medicine and Environmental Health Faculty Publications

This study investigated gender differences in the perceived “pros” and “cons” of smoking using the constructs of decisional balance (DB) and stage of change from the Transtheoretical Model. The population distribution for stage of change among a population-based, cross-sectional survey of 155 current smokers over 40 years was: precontemplation (22.6%), contemplation (41.9%), preparation (35.5%). Results of stepwise regression models indicated significant gender differences in DB were in the preparation stage of change; scores on the DB measure increased 3.94 points (95% CI: 1.94, 5.93) for male smokers. Interventions targeting the “pros” and “cons” of smoking may need to be gender …

Season Of Birth And Risk For Schizophrenia, Seth Roberts

Theses and Dissertations

Background: Schizophrenia is a chronic, debilitating mental disorder characterized by positive (e.g., hallucinations, delusions) and negative (e.g., catatonia, flat affect) signs and symptoms. Many studies suggest that individuals born in winter or spring months are at increased risk for schizophrenia. Study Objectives: 1) To determine whether season of birth affects risk for schizophrenia in the Irish Study of High Density Schizophrenia Families (ISHDSF). 2) To examine, by computer simulation, power to detect genetic associations with schizophrenia under a variety of conditions and using different analytic strategies. 3) To test whether specific genes are associated with schizophrenia in the Irish Case …

Effect Of Metro Living On Oral Cancers In Virginia: 2001-2005, Preeti Sastry

Theses and Dissertations

Background: Forty percent of all head and neck cancers occur in the oral cavity. According to ICD-O (International classification of diseases for oncology) C00-C14 includes cancers of the lip, oral cavity and pharynx. Studies have indicated that increased population density or Metro living have increased oral cancer incidence. The objectives of this study are to look at the distribution of Oral and Oro pharyngeal Cancers in Virginia from 2001-2005 The study aims to determine if there is an association between metro living (beale code 3) and advanced Oral Cancers. This study is also being done to determine if Metro living …

Psychological Distress And Change In A Pediatric Obesity Population, Amy Rebecca Beck

Loma Linda University Electronic Theses, Dissertations & Projects

Pediatric overweight and obesity is a growing national epidemic with 15 percent of children ages 6-19 considered obese and at least 22 percent considered overweight. While there is considerable research pointing to contributing factors of obesity, there is a paucity of research which elucidates what contributes to successful intervention. Considering that by the year 2050, nearly 50 million Americans may be obese, understanding the factors delineating success of weight loss and prevention is a necessity. The purpose of this study was to utilize archival data from the LLU Growing Fit Program to evaluate the levels of psychological distress experienced by …

How Does A Riverine Setting Affect The Lifestyle Of Shellmound Builders In Brazil?, Sabine Eggers, C. C. Petronilho, K. Brandt, C. Jericó-Daminello, J. Filippini, Karl Reinhard

Karl Reinhard Publications

The contact of inland and coastal prehistoric groups in Brazil is believed to have been restricted to regions with no geographical barrier, as is the case in the Ribeira de Iguape valley. The inland osteological collection from the riverine shellmound Moraes (5800–4500 BP) represents a unique opportunity to test this assumption for this region. Despite cultural similarities between riverine and coastal shellmounds, important ecological and site distribution differences are expected to impact on lifestyle. The purpose of this study is thus to document and interpret health and lifestyle indicators in Moraes in comparison to coastal shellmound groups. Specifically we test …

Parental Influences In Child Obesity, Janel Lynn Calinisan

Loma Linda University Electronic Theses, Dissertations & Projects

One of the greatest concerns in American society is peoples’ health. In the past several years there has been an overwhelming increase in obesity in Americans. This concern relates not only to adults, but also to children, as more are found to be overweight. Many factors have been suggested as to why more children are becoming obese, including parenting, demographics, physical activity, nutrition, and biological factors. Studies have shown that parental influence or involvement can be related to child obesity such that neglected children were more likely to be obese in adolescence and sustain it through adulthood. In order to …

The Role Of The Environment In Poverty Alleviation, Paolo Galizzi, Alena Herklotz

Environment

The new millennium raised hopes for a better future for humanity through a new spirit of international cooperation. Participants at the United Nations Millennium Summit agreed on an ambitious agenda for international cooperation that singled out, among other issues, environmental protection and development as key objectives.

The increasing degradation of our planet continues to emphasize the need to conserve and preserve natural resources. Yet with more than half of the global population still living on $2 dollars a day or less, there is also a glaring need for development initiatives to combat poverty.

This book draws on contributions to the …

Surgical Management Of Blunt Pancreatic Trauma: A Modus Operandi Or Individualized Therapy?, Muhammad Rizwan Khan, Kiran Ejaz

Section of General Surgery

The overall rate of blunt pancreatic trauma observed in level one trauma centers is rather low compared to other injuries, with a reported prevalence of 0.4 per 100,000 hospital admissions. The situation may be further complicated by the presence of associated major visceral injuries in these patients. A number of previous reports indicate that blunt pancreatic trauma carries high morbidity and mortality rates, especially when diagnosis is delayed or inappropriate surgery is attempted. Many mandate prompt surgical explorations for organ-specific diagnosis on CT; however other literature and upcoming studies prove otherwise. Over the years, several technologic advances have increased the …

Cardiorespiratory Fitness As A Predictor Of Fatal And Nonfatal Stroke In Asymptomatic Women And Men, Steven P. Hooker, Xuemei Sui, Natalie Colabianchi, John E. Vena, James N. Laditka, Michael J. Lamonte, Steven N. Blair

Faculty Publications

Background and Purpose - Prospective data on the association between cardiorespiratory fitness (CRF) and stroke are largely limited to studies in men or do not separately examine risks for fatal and nonfatal stroke. This study examined the association between CRF and fatal and nonfatal stroke in a large cohort of asymptomatic women and men.

Methods - A total of 46,405 men and 15,282 women without known myocardial infarction or stroke at baseline completed a maximal treadmill exercise test between 1970 and 2001. CRF was grouped as quartiles of the sex-specific distribution of maximal metabolic equivalents achieved. Mortality follow-up was through …

Concept, Design And Implementation Of A Cardiovascular Gene-Centric 50 K Snp Array For Large-Scale Genomic Association Studies, Brendan J. Keating, Sam Tischfield, Sarah S. Murray, Tushar Bhangale, Thomas S. Price, Joseph T. Glessner, Luana Galver, Jeffrey C. Barrett, Struan F A Grant, Deborah N. Farlow, Hareesh R. Chandrupatla, Mark Hansen, Saad Ajmal, George J. Papanicolaou, Yiran Guo, Mingyao Li, Stephanie Derohannessian, Paul I W. De Bakker, Swneke D. Bailey, Alexandre Montpetit, Andrew C. Edmondson, Kent Taylor, Xiaowu Gai, Susanna S. Wang, Myriam Fornage, Tamim Shaikh, Leif Groop, Michael Boehnke, Alistair S. Hall, Andrew T. Hattersley, Edward Frackelton, Nick Patterson, Charleston K W Chiang, Cecelia E. Kim, Richard R. Fabsitz, Willem Ouwehand, Alkes L. Price, Patricia Munroe, Mark Caulfield, Thomas Drake, Eric Boerwinkle, David Reich, A Stephen Whitehead, Thomas P. Cappola, Nilesh J. Samani, A Jake Lusis, Eric Schadt, James G. Wilson, Wolfgang Koenig, Mark I. Mccarthy, Sekar Kathiresan, Stacey B. Gabriel, Hakon Hakonarson, Sonia S. Anand, Muredach Reilly, James C. Engert, Deborah A. Nickerson, Daniel J. Rader, Joel N. Hirschhorn, Garret A. Fitzgerald

Faculty, Staff and Student Publications

A wealth of genetic associations for cardiovascular and metabolic phenotypes in humans has been accumulating over the last decade, in particular a large number of loci derived from recent genome wide association studies (GWAS). True complex disease-associated loci often exert modest effects, so their delineation currently requires integration of diverse phenotypic data from large studies to ensure robust meta-analyses. We have designed a gene-centric 50 K single nucleotide polymorphism (SNP) array to assess potentially relevant loci across a range of cardiovascular, metabolic and inflammatory syndromes. The array utilizes a "cosmopolitan" tagging approach to capture the genetic diversity across approximately 2,000 …

Tending To Richmond's Children: Community Strategies To Bridge Service Gaps, Judith D. Moore, Jessamyn Taylor

National Health Policy Forum

The National Health Policy Forum sponsored a site visit to Richmond, Virginia, in October 2008 to explore social and environmental determinants of children’s health, including the impacts that poverty and exposure to lead-based paint have on birth outcomes, child development, and school readiness; and the community's efforts to address them. Though not large in population terms, Richmond faces many of the social and economic problems often common in larger urban areas—concentrated poverty, migration of wealth and services to the surrounding counties, a high infant mortality rate, and troubled schools. The site visit explored community strategies to improve birth outcomes and …

Weight Regain Is Related To Decreases In Physical Activity During Weight Loss, Xuewen Wang, Mary F. Lyles, Tongjian You, Michael J. Berry, Jack Rejeski, Barbara J. Nicklas

Faculty Publications

Purpose—To examine whether adaptations in physical activity energy expenditure (PAEE) and resting metabolic rate (RMR) during weight loss were associated with future weight regain in overweight/obese, older women.

Research Methods and Procedures—Thirty-four overweight/obese (BMI=25–40 kg/m²), postmenopausal women underwent a 20-week weight loss intervention of hypocaloric diet with (low- or high-intensity) or without treadmill walking (weekly caloric deficit was ~11760 kJ), with a subsequent 12-month follow-up. RMR (via indirect calorimetry), PAEE (by RT3 accelerometer) and body composition (by DXA) were measured before and after intervention. Body weight and self-reported information on physical activity were collected after intervention, …

Characteristics Of A Spina Bifida Population Including North American Caucasian And Hispanic Individuals, Kit Sing Au, Phong X Tran, Chester C Tsai, Michelle R O'Byrne, Jone-Ing Lin, Alanna C Morrison, Amy W Hampson, Paul Cirino, Jack M Fletcher, Kathryn K Ostermaier, Gayle H Tyerman, Sabine Doebel, Hope Northrup

Faculty, Staff and Student Publications

BACKGROUND: Meningomyelocele (MM) is a common human birth defect. MM is a disorder of neural development caused by contributions from genes and environmental factors that result in the NTD and lead to a spectrum of physical and neurocognitive phenotypes.

METHODS: A multidisciplinary approach has been taken to develop a comprehensive understanding of MM through collaborative efforts from investigators specializing in genetics, development, brain imaging, and neurocognitive outcome. Patients have been recruited from five different sites: Houston and the Texas-Mexico border area; Toronto, Canada; Los Angeles, California; and Lexington, Kentucky. Genetic risk factors for MM have been assessed by genotyping and …

Social, Economic And Health Costs Of Unintended Teen Pregnancy: The Circle Of Care Intervention Program In Troup County, Georgia, Andrea M. Brace, Michael Hall, Barry P. Hunt

Journal of the Georgia Public Health Association

Unintended teenage pregnancy in the United States is a public health concern with ramifications that include a variety of social, economic and health costs. It has been estimated that adolescents giving birth before the age of 18 cost the United States at least $9.1 billion dollars annually (NCPTUP, 2008). Latest available national data indicate a slight increase in rates of unintended teen pregnancy after a 15 year period of steady decline. The unintended teen pregnancy rate in Troup County, Georgia in 2006 was 51.9/1,000 which was higher than the national average of 41.9/1,000(Kids Count, 2008). The purpose of this study …

Quantitative Data Analysis Of Multiple Factors Associated With Low Birth Weight In Bibb County, Georgia, Haley D. Jackson, Yudan Wei, Fan Chen

Journal of the Georgia Public Health Association

Objective: This study aims to identify and evaluate significant risk factors associated with low birth weight in Bibb County, Georgia.

Methods: Data used in this study was obtained from the Georgia Department of Human Resources’ Vital Records Offices. The sample consists of 2,346 white and black or African American women giving birth in Bibb County, Georgia in 2005. Logistic regression was used to analyze the risk factors associated with low birthweight in Bibb County, Georgia. The multiple factors analyzed as independent variables included maternal race, maternal education, maternal age group, socioeconomic status, marital status, maternal tobacco use during pregnancy, maternal …

Interning At The Médecins Sans Frontières Operational Office In Geneva, Casie Reiss

Independent Study Project (ISP) Collection

The following report outlines and analyzes the internship and interactive research undertaken by the student, Casie Reiss, during the independent research period. The one-month internship was completed at the Médecins Sans Frontières Operational Office in Geneva in the Operational Communications Department. The subject of research was “The evolution of public positions of the main actors involved in addressing malnutrition.”

Surgeons And Bureaucrats: An Interactive Research Experience At The World Health Organization, Hannah Lust

Independent Study Project (ISP) Collection

During a recent internship at a general hospital in my hometown of Dallas, I could occasionally be found lurking around the main surgical unit. I wanted to be surrounded by the atmosphere of saving lives by manipulating the tiniest capillaries, the most sensitive nerves, the most essential organs. The idea of racing against the clock to save a life, yet having to work with the utmost care is one that is unsettling and enthralling to me all at once. Surgery is infinitely intricate, exceedingly precise, and beautifully complex. And quite simply, it fascinates me. At the same time, I am …

Cancer Control: A Comparison For Progress, Stephanie Lachapelle

Independent Study Project (ISP) Collection

The cancer burden in developing countries like Yemen is significant. These countries are presently ill equipped to adequately provide quality cancer control and care because they have limited financial and medical resources. The first steps to necessary to adequately control the eminent cancer crisis in these countries is to initiate sustainable, cost-effective cancer control strategies. This includes the development of a national cancer control framework, enacting preventative educational programs, increasing biomedical treatment capacity, addressing the need for patient empowerment, and training a significant number of medical professionals. These initiatives can be successfully implemented and supported by networks between various aspects …

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Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Alcohol Use In Pregnancy: A Public Health Problem, Joshua H. Barash

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Coffee Intake And Risk Of Incident Diabetes In Puerto Rican Men: Results From The Puerto Rico Heart Health Program, Barbara J. Fuhrman, Ellen Smit, Carlos J. Crespo, Mario R. Garcia-Palmieri

Community Health Faculty Publications and Presentations

Objective: To study prospectively the association of coffee intake with incident diabetes in the Puerto Rico Heart Health Program cohort, comprising 9824 middle-aged men (aged 35-79 years). Methods: Of 9824 men, 3869 did not provide a fasting blood sample at baseline, 1095 had prevalent diabetes and 131 were not given fasting glucose tests at any subsequent study visit. Thus, the present analysis includes 4685 participants. Diabetes was ascertained at baseline and at two study visits between 1968 and 1975 using fasting glucose tests and self-reports of physician-diagnosed diabetes or use of insulin or hypoglycaemic medication. Logistic regression analysis was used …

Gastric Cancer Among American Indians And Alaska Natives In The United States, 1999–2004, Charles Wiggins, David G. Perdue, Jeffrey A. Henderson, Michael G. Bruce, Anne P. Lanier, Janet J. Kelly, Brenda F. Seals, David K. Espey

United States Public Health Resources

BACKGROUND. Gastric cancer incidence rates for American Indians and Alaska Natives (AI/ANs) historically have exceeded those for non-Hispanic whites (NHWs). Previous reports may have underestimated the true burden of gastric cancer in AI/AN populations because of misclassification of AI/AN race in cancer registries.

METHODS. Population-based cancer registry data from 1999 through 2004 were used to describe gastric cancer incidence in AI/ANs and NHWs in the US. To address misclassification of race, registry data were linked with Indian Health Service administrative records, and analyses were restricted to residents of Contract Health Service Delivery Areas (CHSDA). Disease patterns were assessed …

Shea/Apic Guideline: Infection Prevention And Control In The Long-Term Care Facility, Philip W. Smith, Gail Bennett, Suzanne Bradley, Paul Drinka, Ebbing Lautenbach, James Marx, Lona Mody, Lindsay Nicolle, Kurt Stevenson

United States Department of Veterans Affairs: Publications

Long-term care facilities (LTCFs) may be defined as institutions that provide health care to people who are unable to manage independently in the community.¹ This care may be chronic care management or short-term rehabilitative services. The term nursing home is defined as a facility licensed with an organized professional staff and inpatient beds that provides continuous nursing and other services to patients who are not in the acute phase of an illness. There is considerable overlap between the 2 terms.

More than 1.5 million residents reside in United States (US) nursing homes. In recent years, the acuity of illness …

Is American Health Care Uniquely Inefficient?, Alan M. Garber, Jonathan Skinner

Dartmouth Scholarship

No abstract provided.