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Compliance Documentation For Osha's Bloodborne Pathogen Standard Including Exposure Control Plan And Training, Edward Lloyd Tyerman May 1993

Compliance Documentation For Osha's Bloodborne Pathogen Standard Including Exposure Control Plan And Training, Edward Lloyd Tyerman

Theses

The Occupational Safety and Health Administration's (OSHA) regulation on Bloodborne Pathogens is in full effect since its introduction on December, 1991. This standard mandates that every company whose workers may expect to come into contact with human blood, or other body fluids, during the course of their work develop an Exposure Control Plan, train employees about Bloodborne Pathogens and establish work practice controls. All hospitals, physician and dental offices, ambulance companies, emergency medical technicians, medical laboratories, fire departments, and sites with their own first aid and response teams must comply with the standard.

Bloodborne pathogens include, among others, the human …


Correlates And Infant Mortality: Sudden Infant Death Syndrome Among Black Women In The United States, Paulette Aubrey Apr 1993

Correlates And Infant Mortality: Sudden Infant Death Syndrome Among Black Women In The United States, Paulette Aubrey

Masters Theses

Often referred to as "cot death" or "crib death," sudden infant death syndrome (SIDS) is the single leading cause of infant death in infants aged 28 days to 1 year of life. Although the exact etiology of SIDS remains unknown, epidemiological studies have identified risk factors associated with higher rates of SIDS. In this study, the relationship between sudden infant death syndrome and maternal education among black women who gave birth in the United States during 1983 was examined.

The population for this study consisted of black infants who were born in 1983 and died before their first birthday. Among …


The Aids Project Newsline, Vol.6, No.1 (February 1993), Jeffrey Levensaler, The Aids Project Feb 1993

The Aids Project Newsline, Vol.6, No.1 (February 1993), Jeffrey Levensaler, The Aids Project

AIDS Project Newsline (1991-1996)

No abstract provided.


Exploiting Structural Differences Among Heteroduplex Molecules To Simplify Genotyping The Dqa1 And Dqb1 Alleles In Human Lymphocyte Typing, Peter A. Zimmerman, Mary Carrington, Thomas B. Nutman Jan 1993

Exploiting Structural Differences Among Heteroduplex Molecules To Simplify Genotyping The Dqa1 And Dqb1 Alleles In Human Lymphocyte Typing, Peter A. Zimmerman, Mary Carrington, Thomas B. Nutman

United States Public Health Resources

A novel approach to DNA probe hybridization and heteroduplex analysis, termed directed heteroduplex analysis (DHDA) is presented here to illustrate its utility in simplification of human lymphocyte antigen (HLA)- typing. By strategic labeling of single-stranded probe sequences, DHDA allows the identification of specific heteroduplex structures that contribute to the differentiation of DQAI and DQB1 alleles. Because of the high degree of polymorphism among major histocompatibility complex class 11 second exon sequences, this analysis of 50 different heteroduplex molecules provides evidence of the importance of unpaired bases and mismatched base pairs and their effect on heteroduplex electrophoretic-mobility differences. This strategy is …


Pus, Pox, Propaganda And Progress: The Compulsory Smallpox Vaccination Controversy In Utah, 1899-1901, Eric L. Bluth Jan 1993

Pus, Pox, Propaganda And Progress: The Compulsory Smallpox Vaccination Controversy In Utah, 1899-1901, Eric L. Bluth

Theses and Dissertations

This thesis examines the compulsory smallpox vaccination controversy in Utah, 1899-1901. It looks at the two smallpox epidemics during 1899-1901 and follows the boards of health attempts to eradicate smallpox primarily by compelling the vaccination of school children.

Dr. Theodore B. Beatty, secretary of the State Board of Health, championed the effort to vaccinate all Utahns; however, the opposition led by Charles W. Penrose, editor of the Deseret Evening News, produced anti-compulsion and vaccination information which influenced Utahns to generally oppose vaccination. Consequently, the legislature passed an anti-compulsory vaccination statute over the governor's veto to annul the courts decision …


Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach Jan 1993

Monitoring Of Fungal Spores In An Experimental Indoor Environment To Evaluate Sampling Methods And The Effects Of Human Activity On Air Sampling, Mark P. Buttner, Linda Stetzenbach

Environmental & Global Health Faculty Research

Aerobiological monitoring was conducted in an experimental room to aid in the development of standardized sampling protocols for airborne microorganisms in the indoor environment. The objectives of this research were to evaluate the relative efficiencies of selected sampling methods for the retrieval of airborne fungal spores and to determine the effect of human activity on air sampling. Dry aerosols containing known concentrations of Penicillium chrysogenum spores were generated, and air samples were taken by using Andersen six-stage, Surface Air System, Burkard, and depositional samplers. The Andersen and Burkard samplers retrieved the highest numbers of spores compared with the measurement standard, …


Computer Model For Predicting Aids Among Intravenous Drug Users, Daniel Berleant, R. Ron Goforth, Jun Yuan Jan 1993

Computer Model For Predicting Aids Among Intravenous Drug Users, Daniel Berleant, R. Ron Goforth, Jun Yuan

Journal of the Arkansas Academy of Science

Intravenous drug abuse (IVDA) is an important cause of HIV transmission. Computer simulation is one way to understand and predict the spread of HIV infection among IVDAs. We design and simulate HIV infection among IVDAs and the impact of AIDS on this community, and thereby predict future IVDA population, HIV levels, AIDS levels, and AIDS deaths in this group. The HIV to AIDS, and AIDS to Death latencies are described by probability density functions (PDFs) in this model. Factors such as the recruit, quit, and normal death rate of IVDAs, are considered, as well as the infection and removal rates …


Foreword: Health Care Reform In The United States—The Presidential Task Force, Lawrence O. Gostin Jan 1993

Foreword: Health Care Reform In The United States—The Presidential Task Force, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

This essay serves as the foreword to Implementing U.S. Health Care Reform, a symposium held in 1993.

The exact specifications of the new health care system depend on the package that President Clinton will send to Capitol Hill and the changes that Congress will make in the reform package. Some of the basic structures and organizing principles of the new system that are being considered by the President are already the subject of intense public scrutiny.

The design being considered would involve new relations between the federal government and the states, between the public and private sectors, and between …


The Relationship Of Locus-Of-Control And Altruism To Prehospital Emergency Medical Care Providers Universal Precaution Practices, Joanne L. Wakeham Jan 1993

The Relationship Of Locus-Of-Control And Altruism To Prehospital Emergency Medical Care Providers Universal Precaution Practices, Joanne L. Wakeham

Health Services Research Dissertations

The purpose of this study was to determine the relationship between locus of control, altruism, occupational risk, and personal factors to the frequency of universal precautions practices of prehospital emergency medical care providers. The effects of OSHA's Occupational Exposure to Bloodborne Pathogens; Final Rule on reducing prehospital emergency medical care providers occupational exposure to bloodborne pathogens were also examined. Prehospital emergency medical care providers from municipal and private EMS agencies in the Tidewater Emergency Medical Services region participated in this study. Prehospital emergency medical care providers self-reported perceptions of locus of control, altruism, occupational risk, and universal precautions practices were …


Mathematical Transmission Model Of The Spread Of Hiv Through Sexual Contact And Iv Drug Usage Among Heterosexuals In Western Australia, B. Glockner Jan 1993

Mathematical Transmission Model Of The Spread Of Hiv Through Sexual Contact And Iv Drug Usage Among Heterosexuals In Western Australia, B. Glockner

Theses : Honours

The human immunodeficiency virus (HIV) and its latter stage, the acquired immune deficiency syndrome (AIDS), are still a major health problem in the world and the full extent of the epidemic is unknown. The HIV virus in Australia has been spread mainly through homosexual contact, but this mode of transmission is decreasing while transmission from heterosexual contact and from IV drug use is increasing. The proposed mathematical model concentrates on transmission of the HIV virus through heterosexual contact and IV drug use among heterosexuals in Western Australia. The model parameters will be estimated from surveys conducted by the Australian National …


Aids And The Homeless Of Boston, James J. O'Connell, Joan Lebow Mar 1992

Aids And The Homeless Of Boston, James J. O'Connell, Joan Lebow

New England Journal of Public Policy

Homeless persons with AIDS and HIV infection face significant health hazards during the daily struggle for survival on the streets and in the crowded shelters of our cities. This article offers a historical perspective on the evolution of the AIDS epidemic within the homeless population of Boston and examines the demographics, risk behaviors, and survival statistics of that epidemic. The Boston Health Care for the Homeless Program is presented as a model of service delivery that offers quality health care to homeless persons with AIDS while addressing the special needs of those bound by the immediacy of the next meal …


Community Health Centers: A Resource For Service And Training, Joan Hedgecock, Maria Castro, William B. Cruikshank Mar 1992

Community Health Centers: A Resource For Service And Training, Joan Hedgecock, Maria Castro, William B. Cruikshank

Henry Ford Hospital Medical Journal

The American Medical Student Association (AMSA) Foundation is assisting the U.S. Public Health Service in increasing the number of primary care physicians trained and committed to practice in medically underserved areas. In collaboration with the American Academy of Family Physicians, the Ambulatory Pediatrics Association, and the Society of General Internal Medicine, AMSA conducted an assessment of federally-funded residency programs to identify and describe their affiliations with federally-funded community and migrant health centers (CIMHCs). Of the 260 programs assessed and the 147 responses, 125 offer community-based training. Of these, 73 offer training in primary care centers and 39 offer training in …


Health Priorities Of The State Of Michigan, Vernice Davis Anthony Mar 1992

Health Priorities Of The State Of Michigan, Vernice Davis Anthony

Henry Ford Hospital Medical Journal

No abstract provided.


The Emerging Role Of Htlv-I/Ii And Hiv-1 Among Intravenous Drug Users In Detroit, Anthony F. Ognjan, Chris A. Lewandowski, Bradley T. Belian, John Burczak, Norman Markowitz, Helen Lee, Louis D. Saravolatz Mar 1992

The Emerging Role Of Htlv-I/Ii And Hiv-1 Among Intravenous Drug Users In Detroit, Anthony F. Ognjan, Chris A. Lewandowski, Bradley T. Belian, John Burczak, Norman Markowitz, Helen Lee, Louis D. Saravolatz

Henry Ford Hospital Medical Journal

During 1987-1988, a seroprevalence study of the human immunodeficiency virus (HIV-1) and the human T-cell lymphoma/leukemia virus (HTLV-l/II) was performed among Detroit intravenous drug users unaffiliated with substance abuse programs. Seroprevalence data along with patient demographic information were compared to a similar study performed in 1985-1986. In the earlier study, 12 (12.5%) of 96 individuals tested positive for HIV-1. Of the 74 available negative samples retested in 1987-1988 for retroviruses, 7 (9.5%) tested positive for HTLV-I/II. Thus, the overall retroviral (HIV-1, HTLV-I/II) seropositive rate for 1985-1986 was 22%. In 1987-1988, 11 (15.7%) of 70 individuals tested positive for HIV-1 and …


Parasitology As An Interpretive Tool In Archaeology, Karl J. Reinhard Jan 1992

Parasitology As An Interpretive Tool In Archaeology, Karl J. Reinhard

Karl Reinhard Publications

Parasitological studies of archaeological sites can be used to interpret past behavior and living conditions. During the 1980s problem-oriented research into prehistoric- and historical-period parasitism developed and resulted in thefield of archaeoparasitology. Archaeoparasitology attempts to integrate parasite data into archaeological theory and interpretation. Within the last decade, four major archaeoparasitological laboratories emerged. They developed interpretive frameworks that apply parasitological data to a remarkable variety of prehistoric behaviors. Parasite remains can be used to reconstruct aspects of diet, health, and other behaviors such as transhumance and trade. Finally. analysis of the distribution of parasite remains can be used to interpret aspects …


Risk And Rationality: The Centers For Disease Control And The Regulation Of Hiv-Infected Health Care Workers, Mary Anne Bobinski Jan 1992

Risk And Rationality: The Centers For Disease Control And The Regulation Of Hiv-Infected Health Care Workers, Mary Anne Bobinski

Faculty Articles

The publicity surrounding the Bergalis case has created a new and powerful fear for some-the fear of contracting a fatal disease while obtaining medical or dental care. Following Bergalis' congressional testimony, Congress passed a bill requiring states to regulate HIV-infected health care workers (HCWs). Responding to constituents' fears, state legislatures had already been debating a wide range of bills designed to confront the risk of HIV transmission in health care settings. Private actors, such as hospitals and insurers, feared litigation or loss of business if the public perceived them to be ignoring the problem of HIV infection among HCWs. As …


Coprolite Analysis: A Biological Perspective On Archaeology, Karl J. Reinhard, Baughn M. Bryant Jr Jan 1992

Coprolite Analysis: A Biological Perspective On Archaeology, Karl J. Reinhard, Baughn M. Bryant Jr

Karl Reinhard Publications

The most remarkable dietary remains recoverable from archaeological contexts are coprolites. Coprolites are desiccated or mineralized feces that are preserved in sheltered and open sites in arid regions, primarily in the New World. These dietary remains are remarkable from several perspectives. They typically contain a variety of macroscopic and microscopic remains that form interrelated data sets for the reconstruction of diets. Because contexts containing coprolites are typified by excellent preservation, the remains coprolites contain tend to be in better states of preservation than dietary remains recovered from nonfecal deposits. Coprolites also contain the well-preserved remains of intestinal parasites and pathogens …


Vertebral Pathology In Prehistoric And Historic Skeletons From Northeastern Nebraska, Karin L. Sandness, Karl J. Reinhard Jan 1992

Vertebral Pathology In Prehistoric And Historic Skeletons From Northeastern Nebraska, Karin L. Sandness, Karl J. Reinhard

Karl Reinhard Publications

Vertebral pathology has long been a useful criterion for anthropologists in the assessment of activity patterns, stress, and general health of extinct peoples. This method of analysis, however, has never been applied to the peoples of the Nebraska Great Plains. This study is the first to concentrate on the indigenous Native Americans of this region, examining the spinal pathology present in the prehistoric and historic skeletal remains. Pathology present in the form of spondylolysis, Schmorl's nodes, osteophytosis (degenerative disc disease), and osteoarthritis (degenerative joint disease), provides evidence to suggest differing activity patterns and levels of stress in Plains groups before …


Dan Canyon Burial: A Piii Burial In Glen Canyon National Recreation Area, Steve Dominguez, Karl Reinhard, Kari L. Sandness, Cherie A. Edwards, Dennis Danielson, F. A. Calabrese, Chris Kincaid Jan 1992

Dan Canyon Burial: A Piii Burial In Glen Canyon National Recreation Area, Steve Dominguez, Karl Reinhard, Kari L. Sandness, Cherie A. Edwards, Dennis Danielson, F. A. Calabrese, Chris Kincaid

Karl Reinhard Publications

The Dan Canyon burial was discovered at a time when the philosophy, ethics, and legislation concerning the study of human remains are in a state of flux. A number of important sensitive issues germane to managers, archeologists, and American Indians are discussed in the introduction. The subsequent analysis provides a detailed scientific account of these remains and a glimpse of a segment of a people's past lifeway while remaining sensitive to the wishes of the American Indians.

The burial and associated grave goods of site 42SA21339 were exposed by wave action in a location frequented by boaters at the Glen …


Dental Patients' Knowledge, Beliefs, And Perceptions About Dentistry And Aids, Sara S. Plaspohl Jan 1992

Dental Patients' Knowledge, Beliefs, And Perceptions About Dentistry And Aids, Sara S. Plaspohl

College of Graduate Studies: Theses & Dissertations (1964–2006)

The majority of Americans view AIDS as the most important health problem faced today. Despite efforts to educate the public, the literature suggests that misperceptions exist concerning HIV transmission. The documented case of a Florida dentist who transmitted the HIV virus to five dental patients focused the public's attention on its perceived vulnerability to contracting HIV during a dental visit. The purpose' of this descriptive study was to identify the dental patient's perceived risk of acquiring the AIDS virus during a dental visit and to then determine whether the perceived risk was related to the patient's level of oral hygiene. …


Preliminary Epidemiological Interpretation Of The Intrinsic And Extrinsic Factors Contributing To The Coverage And Participation Rates Of The Vaccination Program In Arssi, Ethiopia, Muchie Kidanu Dec 1991

Preliminary Epidemiological Interpretation Of The Intrinsic And Extrinsic Factors Contributing To The Coverage And Participation Rates Of The Vaccination Program In Arssi, Ethiopia, Muchie Kidanu

Electronic Theses and Dissertations

Many immunization programs in developing countries arr now undergoing a period of rapid utilization. Innovative strategies, such as immunization holidays, are being tried. Political commitment and enthusiasm are high. There is a strong desire by health professionals to protect the lives of many children from the untimely death and/or disability resulting from infectious diseases preventable by vaccination.

Evaluation of an immunization program can benefit other elements of the health system, particularly those that are not amenable to objective evaluation as immunization. In this case, immunization can serve as an indicator of the overall performance of the health system. The problems …


Isolation And Expression Of A Gene Cluster Responsible For Biosynthesis Of The Glycopeptidolipid Antigens Of Micobacterium Avium, John T. Belisle, Lisa Pascopella, Julia M. Inamine, Patrick J. Brennan, William R. Jacobs Jr. Nov 1991

Isolation And Expression Of A Gene Cluster Responsible For Biosynthesis Of The Glycopeptidolipid Antigens Of Micobacterium Avium, John T. Belisle, Lisa Pascopella, Julia M. Inamine, Patrick J. Brennan, William R. Jacobs Jr.

Public and Community Health Sciences Faculty Publications

Bacteria within the Mycobacterium avium complex are prominent in the environment and are a source of serious disseminated infections in patients with AIDS. Serovars of the M. avium complex are distinguished from all other mycobacteria and from one another by the presence of highly antigenic glycolipids, the glycopeptidolipids, on their surfaces. A genomic library of DNA from serovar 2 of the M. avium complex was constructed in the Escherichia coli-Mycobacterium shuttle cosmid, pYUB18, and used to clone and express in Mycobacterium smegmatis the genes responsible for the biosynthesis of the oligosaccharide segment of the M. avium serovar 2-specific glycopeptidolipid. The …


Dysfunctional Attitudes, Life Stress And Coping Processes, Deborah Desalliers Sep 1991

Dysfunctional Attitudes, Life Stress And Coping Processes, Deborah Desalliers

Loma Linda University Electronic Theses, Dissertations & Projects

The findings of recent investigations earmarked chronic daily stressors as being highly related to stress levels. In addition, researchers are promoting a more integrative model of stress. The stress response is no longer thought of in strictly linear terms, i.e. an event causes stress. Rather, cognitive factors, existing within the human mind itself, strongly influence our coping processes and the chronic stress we experience.

Canonical correlation analysis was used to study how dysfunctional attitudes, a negative cognitive factor, were related to individuals' daily hassles and coping processes. An increase in dysfunctional attitudes was found to correspond to an increase in …


Use Of Pollen Concentration In Paleopharmacology: Coprolite Evidence Of Medicinal Plants, Karl Reinhard, Donny L. Hamilton, Richard H. Hevly Jul 1991

Use Of Pollen Concentration In Paleopharmacology: Coprolite Evidence Of Medicinal Plants, Karl Reinhard, Donny L. Hamilton, Richard H. Hevly

Karl Reinhard Publications

Nearly 2,400 plant species have been documented ethnographically as having medicinal value among Native Americans. Therefore, it is not surprising that evidence of medicinal plants appears in some of the over 1,000 coprolites analyzed from the southwestern U.S. Three medicinal species identified in pollen analysis of coprolites are discussed. Willow (Salix) is the most common analgesic in the Native American pharmacopoeia. Prehistoric use of this plant is documented in coprolites from Bighorn Cave in the Black Mountains of Arizona and also in a burial from the Mimbres Valley, New Mexico. Historically, Mormon tea (Ephedra) served as …


Antimicrobial Chemotherapy In The Intensive Care Unit, Louis D. Saravolatz Jun 1991

Antimicrobial Chemotherapy In The Intensive Care Unit, Louis D. Saravolatz

Henry Ford Hospital Medical Journal

No abstract provided.


Porcine Bioprosthetic Aortic Valve Endocarditis With Ring Abscess And Aortic Stenosis, Reda A. Girgis, Howard Rosman, Ramon Del Busto, Maryann Fitzmaurice, Norman A. Silverman Jun 1991

Porcine Bioprosthetic Aortic Valve Endocarditis With Ring Abscess And Aortic Stenosis, Reda A. Girgis, Howard Rosman, Ramon Del Busto, Maryann Fitzmaurice, Norman A. Silverman

Henry Ford Hospital Medical Journal

Porcine bioprosthetic valve endocarditis is an infrequent but serious complication of valve replacement surgery. Ring (or annular) abscess is a frequent finding in mechanical valve endocarditis. In contrast, porcine valve endocarditis most often involves the cusps, and annular infection is uncommon. Porcine valvular dysfunction secondary to endocarditis usually takes the form of incompetence, whereas stenosis is less frequent. We report a case of a 76-year-old female who developed endocarditis wilh Staphylococcus epidermidis nine months after placement of a Carpenter-Edwards porcine aortic valve. Her initial presentation included complete heart block and moderate aortic stenosis. Transesophageal echocardiography aided the diagnosis by demonstrating …


Identification Of Health Promotion Behaviors, Perceived Health Status And Perceived Health Education Needs Of Older Women, Susan Carol Fellinger Reynolds Apr 1991

Identification Of Health Promotion Behaviors, Perceived Health Status And Perceived Health Education Needs Of Older Women, Susan Carol Fellinger Reynolds

Ellmer School of Nursing Theses & Dissertations

The health-promoting behaviors, perceived health status, and perceived health education needs of older women were identified in this non-experimental, descriptive, correlational study. Fifty women over 60 years of age, living in three housing complexes for the elderly, disabled and handicapped in two southeastern United States cities were asked to complete The Health-Promoting Lifestyle Profile, The Perceived Health Status Questionnaire, The Health Education Needs Questionnaire, and Demographic Data Sheet. It was concluded that the women engaged in a high level of health-promoting behaviors. The participants rated their health as good and rated their health as good compared to that of other …


Molecular Epidemiologic Techniques In Analysis Of Epidemic And Endemic Shigella Dysenteriae Type 1 Strains, Nancy A. Strockbine, Julie Parsonnet, Katherine Greene, Julia A. Kiehlbauch, I. Kaye Wachsmuth Jan 1991

Molecular Epidemiologic Techniques In Analysis Of Epidemic And Endemic Shigella Dysenteriae Type 1 Strains, Nancy A. Strockbine, Julie Parsonnet, Katherine Greene, Julia A. Kiehlbauch, I. Kaye Wachsmuth

United States Public Health Resources

During 1988 the number of Shigella dysenteriae type 1 infections reported in the United States increased fivefold. To determine if recent isolates from Mexico were related to those that caused epidemics of dysentery worldwide, Southern hybridization analysis was done with Shiga toxin and ribosomal RNA gene probes. Western hemisphere and Eastern Hemisphere strains differed by the size of a single EcoRI fragment carrying the Shiga toxin genes. Three ribosomal DNA (rDNA) patterns were observed, which correlated with the strain;s continental origin for 81 of 83 isolates tested. Together the Shiga toxin and rDNA probe results indicated that recent Mexican …


The Effect Of Psychosocial Factors On The Immune Response Of Hiv Infected Individuals As Measured By The Extent Of Relationship With Cd-4 T Cell Count And Physical Symptoms, Richard R. Taylor Jan 1991

The Effect Of Psychosocial Factors On The Immune Response Of Hiv Infected Individuals As Measured By The Extent Of Relationship With Cd-4 T Cell Count And Physical Symptoms, Richard R. Taylor

Theses

The effect of psychosocial factors on the immune response of HIV infected human subjects was assessed by measuring the degree of relationship to CD-4 T cell count and physical symptoms.

Twenty six participants (22 white and 2 black males) all who had been diagnosed as HIV positive completed a battery of 11 psychological tests and a social and medical history questionnaire. Fifty four psychosocial factors were selected as having the potential to have a significant effect on immune response.

Correlational analyses yielded no strong relationships between the psychosocial factors and CD-4 T cell count or physical symptoms. Moderate associations were …


Genetic Discrimination: The Use Of Genetically Based Diagnostic And Prognostic Tests By Employers And Insurers, Lawrence O. Gostin Jan 1991

Genetic Discrimination: The Use Of Genetically Based Diagnostic And Prognostic Tests By Employers And Insurers, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

This paper analyzes the law, ethics and public policy concerning "genetic discrimination," defined as the denial of rights, privileges or opportunities on the basis of information obtained from genetically based diagnostic and prognostic tests. The Human Genome Initiative will enhance the ability to gather and organize information that may predict a person's future potential and disabilities. Enormous human benefits may ensue from understanding the etiology and pathophysiology of genetic disorders, including disease prevention through genetic counseling, and treatment of the disorders through genetic manipulation. This information will help clinicians understand and eventually treat many of the more than 4,000 diseases …