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A Case Of Ige Myeloma: Methodology And Review Of The Literature, Pat A. Allevato, Michael J. Deegan, Jau-Wen Chu, Mary B. Perry, Carolyn L. Barth

Henry Ford Hospital Medical Journal

A 56-year-old man presented with a one-year history of progressive weakness predominantly affecting his extremities and persistent low back pain. Ouchterlony immunodiffusion of the concentrated urine detected a marked increase in lambda light chains. A sternal bone marrow documented a diagnosis of multiple myeloma. Screening high resolution agarose gel electrophoresis revealed diffuse hypogammaglobulinemia and, retrospectively, an equivocal, faint band which migrated in the fast gamma region. By using a combination of Immunoelectrophoresis and immunofixation electrophoresis, this questionable band was determined to represent an IgE lambda monoclonal protein. Radioimmunoassay for IgE documented a serum concentration of 50.6 mg/dl. No intact IgE …

Rapidly Progressive Pancytopenia, Hepatomegaly, And Abnormal Lung Uptake Of Colloid In Systemic Lupus Erythematosus: Possible Saturation Of Reticuloendothelial System With Blood Elements, Tetsushi Sakurai, Kiyoshi Fukuda, Ichiro Kono, Teizo Kabashima, Kazuhide Yamane, Heihachiro Kashiwagi

Henry Ford Hospital Medical Journal

A patient with systemic lupus erythematosus developed severe abdominal pain and tender hepatomegaly associated with progressive pancytopenia and elevated serum levels of circulating immune complexes. Liver scintigram demonstrated extreme hepatomegaly with poor colloid uptake and splenomegaly with increased colloid uptake. An unusual accumulation of colloid in the lungs was also noted. Subsequent clinical and laboratory studies raised the possibility of saturation of the reticuloendothelial system in the liver by circulating immune complexes and blood cells, a condition demonstrated in experimental animals, but not hitherto well documented in the human immune complex disorder.

Tubal Lavage In The Management Of Ectopic Pregnancy, Samuel A. Motanya, William H. Pfeffer, Emile Sandelin, C. James Chuong

Henry Ford Hospital Medical Journal

No abstract provided.

Clinical Trials: I. Design And Ethical Issues, Barbara Tilley

Henry Ford Hospital Medical Journal

No abstract provided.

Editorial, Raymond C. Mellinger

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Commencement Program 1984, Loma Linda University

Commencement Programs

CONTENTS

2 | 1984 Events of Commencement

3 | Academic Procession

4 | The Speakers

7 | The Honorees

Order of Program

• School of Medicine, 12
• Graduate School, 18
• School of Dentistry, 23
• School of Nursing, 29
• School of Education, 32
• College of Arts and Sciences, 38
• School of Allied Health Professions, 45
• School of Health, 50

Chronic Respiratory Disease Symptom Effects Of Long-Term Cumulative Exposure To Passive Tobacco Smoke And To Ambient Levels Of Tsp, Oxidants, So2, And No2 In Southern California, Gary L. Euler

Loma Linda University Electronic Theses, Dissertations & Projects

To assess risk of chronic respiratory disease symptoms due to long-term exposure to the ambient levels of TSP, oxidants, SO2 and NO2 in photochemical air pollution, symptoms were ascertained using NHLBI questions on 8,572 Southern California Seventh-day Adventist, nonsmokers, 25 years and older, who lived eleven years or longer in their 1977 residential area. Tobacco smoke, active and passive, and occupational exposures were measured by questionnaires, as well as lifestyle characteristics relative to pollution exposure such as time spent outside and residence history. A pulmonary function feasibility study was done on a subsample of 86 women 50-64 years of age …

The Effect Of Electroshock On The Passage Of Bacteria From A Contaminated Transducer Past A Protective Membrane Into A Disposable Chamber Dome, Patricia K. Taylor Pothier

Loma Linda University Electronic Theses, Dissertations & Projects

Infection related to use of Intra-arterial Hemodynamic Monitoring Devices is a serious complication. In an attempt to decrease the risk of infection presterilized chamber domes were developed to isolate the patient vascular system from the pressure transducer. Users were informed by manufacturers of the domes that routine decontamination of transducer heads was not necessary. Since the development of these disposable chamber domes infection outbreaks have continued to occur. Epidemiological investigation has implicated contact transmission of bacteria due to poor handling techniques in some outbreaks. However, in other outbreaks the source of the epidemic was found to be contaminated transducer heads …

Facilitation Of C.O.P.D. Patient Compliance In Self-Administration Of Medical Modalities Through In-Hospital Specialized Education Program, Elizabeth Maddox

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

L'Oxyde D'Éthylène Dans Les Établissements De Santé Au Québec : Problématique Et Mesures De Contrôle, Institut De Recherche Robert-Sauvé En Santé Et En Sécurité Du Travail, Association Paritaire Pour La Santé Et La Sécurité Du Travail Du Secteur Affaires Sociales

Rapports de recherche scientifique

No abstract provided.

Screening Of Patients At High Risk For Cancer, Robert M. O'Bryan

Henry Ford Hospital Medical Journal

A cancer other than non-melanoma skin cancer will occur in one of every seven persons. Individuals with higher risks for cancer are those with increasing age, hereditary disorders, and a family history of cancer. Lifestyle, especially the use of tobacco and alcohol, diet, and perhaps behavioral patterns influence the risk. Less well understood but clearly pertinent risk factors include environmental and occupational exposures. The risk factors specific for breast cancer include a positive family history of breast cancer, history of mastopathy, age at first pregnancy greater than 35 years, early menarche with late menopause, and history of carcinoma of the …

Brief Communication: Streptokinase For Deep Venous Thrombosis, Barry Lesser, Maria A. Sawdyk

Henry Ford Hospital Medical Journal

No abstract provided.

Pericardial Tamponade In Acute Myeloid Leukemia, R. P. Warrier, K. R. Kini, R. Singh, K. Maeda, I. Barr, F. M. Jara

Henry Ford Hospital Medical Journal

We are reporting a case of acute myeloid leukemia in a child with pericardial effusion and cardiac tamponade, with a review of the literature. Morphologic and cytochemical evidence was used to diagnose acute myeloid leukemia, and radiologic, electrocardiographic, echocardiographic, cytologic, and histologic evidence confirmed the diagnosis of tamponade and pericardial leukemic involvement. Pericardiotomy and pericardial window drainage successfully relieved the tamponade, and conventional chemotherapy was used to induce a remission.

Cushing's Disease Due To Pituitary Carcinoma, M. Saeed Zafar, R. C. Mellinger, J. L. Chason

Henry Ford Hospital Medical Journal

Criteria for the diagnosis of pituitary carcinoma are subject to controversy. Some authors do not accept the demonstration of cellular anaplasia alone as sufficient to establish the diagnosis but require evidence of metastatic disease in order to label a pituitary tumor as malignant. However, pituitary tumors can metastasize even in the absence of anaplasia. The present case of Cushing's disease and pituitary carcinoma had no clinical evidence of metastases when first reported. Partial surgical removal of the tumor followed by irradiation resulted in clinical remission of the Cushing's syndrome, but two years later progressive uncontrollable recurrence of the disease ended …

Peritoneal Lavage Red Blood Cell And White Blood Cell Count: A Prospective Comparison Of Usefulness, Eugene Meyer, James C. Gruenberg

Henry Ford Hospital Medical Journal

Prospectively, 637 patients with blunt or penetrating trauma to the lower chest or abdomen had quantitative peritoneal lavage red blood cell (RBC) and white blood cell (WBC) counts as part of their initial diagnostic evaluation. Statistically, the lavage RBC count (error rate: 6.8%) was a superior test to the lavage WBC count (error rate: 9.7%) (chi sq=9.2564, p=0.0024). See Appendix. When the lavage RBC and WBC tests agreed, the predictive value was high: 94% (46/49) when both were positive and 95% (521/549) when both were negative. When the lavage RBC test was positive and the lavage WBC test was negative, …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Why Cancer?, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Family History As A Marker For Increased Risk Of Breast Cancer And Colon Cancer, Robert A. Norum

Henry Ford Hospital Medical Journal

Cancer of the breast and colon are well known to occur with high frequency in families with certain inherited cancer syndromes. These cancers also occur with increased frequency in families which do not have a recognizable genetic cancer syndrome. The fact of familial occurrence can be used to identify people with increased risk of cancer. In high-risk people methods for early detection can be developed which may reduce morbidity and mortality from these cancers, as has been done for certain inherited cancer syndromes.

External Beam Treatment Of Inoperable Non-Small Cell Carcinoma Of The Lung, H. Gunter Seydel

Henry Ford Hospital Medical Journal

External beam radiation therapy for unresectable non-small cell carcinoma of the lung has produced significant survival in patients with disease limited to one hemithorax. New approaches to improve the results of radiation treatment of these patients include interstitial implantation, the use of hypoxic cell sensitizers, biologic response modifiers, as well as changes in the technique of radiation therapy. This includes the use of modern computerized tomographic scanning technology for better definition of tumor volume as well as the use of two fractions per day in the treatment of non-small cell carcinoma of the lung. Initial results of these studies are …

The Spectrum Of B Cell Neoplasia, Michael J. Deegan

Henry Ford Hospital Medical Journal

Recent progress in our understanding of the immune system and the development of new techniques that permit the precise identification of lymphocytes have permitted a reexamination of lymphoid neoplasms. Most of the non-Hodgkin's lymphomas and lymphocytic leukemias have been characterized as T or B cell neoplasms and have been shown to possess features similar to those expressed by normal lymphoid cells at different stages of maturation. The clinical significance and therapeutic implications of these discoveries are now being explored. This paper presents a concise overview of the differentiation of human B lymphocytes, the surface and cytoplasmic markers that permit their …

Preoperative Chemotherapy And Irradiation In The Treatment Of Soft Tissue Sarcomas Of The Lower Extremities: Preliminary Report Of Experience At Henry Ford Hospital, S. David Nathanson

Henry Ford Hospital Medical Journal

The development of effective chemotherapy and improved techniques of radiation therapy offer the possibility of managing soft tissue sarcomas so that surgery may need to be less radical than in the past and amputation can be avoided. The low rates of local-regional and systemic recurrence that have resulted from using innovative combinations of chemotherapy, radiation therapy, and conservative surgery encouraged us to use preoperative intraarterial adriamycin (doxorubicin) with or without radiation therapy for three cases of soft tissue sarcomas of the lower extremities. The rationale for this therapy is also discussed.

The Current Controversies In Surgical Management Of Early Breast Cancer, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Elevated Serum Transaminase As A Presenting Clue For Precirrhotic Hemochromatosis, Lester P. Kobylak

Henry Ford Hospital Medical Journal

For patients in whom unexplained elevations in SGOT and SGPT concentrations are found, determination of the serum iron level is recommended to screen for asymptomatic precirrhotic hemochromatosis. Care must be taken to differentiate between hereditary hemochromatosis and secondary iron accumulation due to liver disease.

Is Normal "Normal"?, Craig C. Foreback

Henry Ford Hospital Medical Journal

No abstract provided.

Polymicrobal Pneumonia In A Corticosteroid-Treated Patient With Chronic Obstructive Lung Disease, John R. Haapaniemi, John Popovich Jr.

Henry Ford Hospital Medical Journal

The immunosuppressive properties of corticosteroids are well established and cause a depression of pulmonary defense mechanisms. We report the case of a patient treated with short-term corticosteroids for an exacerbation of chronic obstructive lung disease who developed a multiple organism pneumonia.

Neurosonology: An Update, Beatrice L. Madrazo, Manuel Dujovny, Juan Fuentes, Michael A. Sandler, Madelyne Galvin

Henry Ford Hospital Medical Journal

Recent technological advances in diagnostic ultrasound have resulted in the development of high-resolution, portable real-time scanners. In neurological ultrasound, these devices have been particularly useful for detecting intracranial hemorrhage in premature infants. Sonography is now being used during neurosurgical procedures to help in localizing masses for resection and biopsy, as well as in the placement of shunt catheters. The applications of neurosonology and our experience with intraoperative neurosonology are reported in this review.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Mosquitoes As Vectors Of Disease In Minnesota, John W. Washburn

Journal of the Minnesota Academy of Science

Diseases due to mosquito-borne viruses occur every summer in Minnesota. The incidence of Western encephalitis and LaCrosse encephalitis is usually low, but outbreaks of Western encephalitis have occurred in the past. Evidence of Jamestown Canyon virus activity has been found in Minnesota. This virus may represent a newly-recognized cause of central nervous system disease and encephalitis. The epidemiology of the mosquito-borne encephalitis viruses found in Minnesota and the methods of disease surveillance and control are discussed.

Ua35/11 Student Honors Research Bulletin, Wku Honors Program

WKU Administration Documents

The WKU Student Honors Research Bulletin is dedicated to scholarly involvement and student research. These papers are representative of work done by students from throughout the university.

• Albin, Bettye. Hawthorne's Narrator in the Blithedale Romance: A New Cover for an Old Friend
• Allen, Christopher. With Just Pride: The Naval History of the Warships USS Enterprise
• Barrett, Shelly. Structuralism
• Bolton, Joe. Wallace Stevens and Twentieth Century Aesthetics
• Bush, Paul. The Acceptance of Grace in Flannery O'Connor's Short Stories
• Gasparello-Moore, Nina. A Comparison of a Naïve and Simple Regression Forecasting Model for the Dow Jones Industrial Average
• Henry, Lynn. The Bureaucratic and …