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Articles 4711 - 4740 of 54664
Full-Text Articles in Entire DC Network
Improving Cooking Skills, Lifestyle Behaviors, And Clinical Outcomes For Adults At Risk For Cardiometabolic Disease: Protocol For A Randomized Teaching Kitchen Multisite Trial (Tk-Mt), Jennifer Massa, Candace Sapp, Kate Janisch, Mopelola A Adeyemo, Auden Mcclure, Natalia I Heredia, Deanna M Hoelscher, Tannaz Moin, Shaista Malik, Wendelin Slusser, David M Eisenberg
Improving Cooking Skills, Lifestyle Behaviors, And Clinical Outcomes For Adults At Risk For Cardiometabolic Disease: Protocol For A Randomized Teaching Kitchen Multisite Trial (Tk-Mt), Jennifer Massa, Candace Sapp, Kate Janisch, Mopelola A Adeyemo, Auden Mcclure, Natalia I Heredia, Deanna M Hoelscher, Tannaz Moin, Shaista Malik, Wendelin Slusser, David M Eisenberg
Faculty, Staff and Student Publications
BACKGROUND/OBJECTIVES: This protocol describes a study to investigate the feasibility and preliminary efficacy of a novel Teaching Kitchen Multisite Trial (TK-MT) for adults with cardiometabolic abnormalities. The TK-MT protocol describes a hybrid lifestyle intervention combining in-person and virtual instruction in culinary skills, nutrition education, movement, and mindfulness with community support and behavior change strategies. This 18-month-long randomized controlled trial aims to evaluate the feasibility of implementing a 12-month, 24 class program, assess preliminary study efficacy, and identify barriers and facilitators to implementation.
METHODS: The intervention program includes 16 weeks of intensive hands-on culinary and lifestyle education classes followed by eight …
Keeping Kids Safe At Meals: Preventing And Responding To Choking, Mia Dustin, Savannah Daines, Stacy Bevan, Palak Gupta, Mateja R. Savoie-Roskos
Keeping Kids Safe At Meals: Preventing And Responding To Choking, Mia Dustin, Savannah Daines, Stacy Bevan, Palak Gupta, Mateja R. Savoie-Roskos
All Current Publications
Introducing solid foods is an exciting developmental milestone, but it can also raise concerns about choking for parents and caregivers. Choking occurs when an object, such as food or a toy, blocks a child’s airway and prevents air from moving in and out of the lungs. This fact sheet offers practical guidance on how to prevent food-related choking, recognize the signs of a choking emergency, and what to do if a child is choking.
From Theory To Practice: Integrating Safe Patient Handling And Mobility Into Occupational Therapy Curriculum (Part 2/2), Kimberly Santorufo, Asha Roy
From Theory To Practice: Integrating Safe Patient Handling And Mobility Into Occupational Therapy Curriculum (Part 2/2), Kimberly Santorufo, Asha Roy
The Open Journal of Occupational Therapy
Occupational therapy academic institutions continue to teach manual patient handling as the standard of practice despite recent evidence, legislation, and guidelines from the American Occupational Therapy Association on hazards of manual approaches. A paradigm shift is necessary in occupational therapy academic curriculums to include didactic education and hands-on training of safe patient handling and mobility informed approaches. There is currently no standard of practice available in occupational therapy education on how to incorporate safe patient handling and mobility into preexisting curriculum, which emphasizes manual patient handling as the standard of care. The guidelines presented offer academic institutions recommendations on how …
From Theory To Practice: Integrating Safe Patient Handling And Mobility Into Occupational Therapy Curriculum (Part 1/2), Kimberly Santorufo, Asha Roy
From Theory To Practice: Integrating Safe Patient Handling And Mobility Into Occupational Therapy Curriculum (Part 1/2), Kimberly Santorufo, Asha Roy
The Open Journal of Occupational Therapy
Occupational therapists are at high-risk of musculoskeletal injury because of the manual and physical demands of job-related tasks. Many occupational therapists are sustaining injuries or changing careers because of an injury. Safe patient handling and mobility approaches should be used in occupational therapy practice to ensure the safety of both patient and therapist while assisting patients in meeting occupation-based and patient-centered goals. However, despite legislation, guidelines from the American Occupational Therapy Association, and recent evidence, most occupational therapy academic programs and educators continue to teach manual patient handling as the standard of practice. To ensure safety, longevity, and career-retention, academic …
Adverse Childhood Experiences: Healing Through Storytelling And Mindful Narrative Therapy, Julie Kemp
Adverse Childhood Experiences: Healing Through Storytelling And Mindful Narrative Therapy, Julie Kemp
Mindfulness Studies Theses
This study presents research about the nature and prevalence of adverse childhood experiences (ACEs), the mental and physical impacts to individuals exposed to ACEs, and incorporating mindfulness practices into therapeutic approaches to treating them, particularly Mindfulness-Based Narrative Therapy (MBNT). It is important because ACEs have become a global crisis, with the potential for interfering with psychological and physical development, early mortality, and other harmful life outcomes. This thesis provides critical information for mindfulness teachers and practitioners, therapists, educators, regulators, parents, and individuals subjected to ACEs.
The methodology includes extensive literature searches for narrative therapy and mindfulness-based interventions (MBIs) in peer-reviewed …
Harm Reduction Without Supportive Policing: Experiences Of Drug Users In Nepal, Chandra Jha, Dennis Donovan
Harm Reduction Without Supportive Policing: Experiences Of Drug Users In Nepal, Chandra Jha, Dennis Donovan
Journal of Social, Behavioral, and Health Sciences
This study explored the impact of drug criminalization and policing on harm reduction efforts in Nepal. In contexts marked by widespread corruption, drug criminalization often exacerbates the mistreatment by law enforcement of people who use drugs (PWUD), creating substantial barriers to their accessing harm reduction services. Utilizing a constructivist framework and a modified grounded theory approach, we conducted in-depth interviews with 20 PWUD to examine their experiences with drug use, interactions with police, and the consequent effects on harm reduction efforts. Three key themes emerged: the exploitation of PWUD as a significant source of income for corrupt police officers, the …
Associations Between Social Determinants Of Health And Mental Health Disorders Among U.S. Population: A Cross-Sectional Study, S. Tanarsuwongkul
Associations Between Social Determinants Of Health And Mental Health Disorders Among U.S. Population: A Cross-Sectional Study, S. Tanarsuwongkul
Faculty Publications
Aims
The impact of social determinants of health (SDOH) on mental health is increasingly realized. A comprehensive study examining the associations of SDOH with mental health disorders has yet to be accomplished. This study evaluated the associations between five domains of SDOH and the SDOH summary score and mental health disorders in the United States.
Methods
We analyzed data from a diverse group of participants enrolled in the All of Us research programme, a research programme to gather data from one million people living in the United States, in a cross-sectional design. The primary exposure was SDOH based on Healthy …
Association Between Joint Exposure To Ambient Air Pollutants And Carotid Plaque: The Mediating Role Of Cardiometabolic Risk Factors, Yunfei Li, Ze Han, Xiaoyu Zhao, Yueruijing Liu, Zhiyuan Wu, Jinqi Wang, Xia Li, Xiuhua Guo, Lixin Tao
Association Between Joint Exposure To Ambient Air Pollutants And Carotid Plaque: The Mediating Role Of Cardiometabolic Risk Factors, Yunfei Li, Ze Han, Xiaoyu Zhao, Yueruijing Liu, Zhiyuan Wu, Jinqi Wang, Xia Li, Xiuhua Guo, Lixin Tao
Research outputs 2022 to 2026
Background: Research has shown that exposure to joint air pollution is related to atherosclerosis, but little evidence has been found for carotid plaques. Our objective is to assess the association between exposure to joint air pollutants and carotid plaque and explore the mediating role of cardiometabolic factors in this relationship. Methods: The Beijing Health Management Cohort (BMHC) study followed participants recruited from 2013 to 2014 until December 31, 2020. All participants underwent carotid ultrasound and were free of carotid plaque at baseline. A satellite-based land-use regression (LUR) model was applied to estimate air pollution exposure. The joint exposure to air …
What Factors Influenced Covid-19 Vaccine Hesitancy? Evidence From Social Media, Huseyin Zeyd Koytak
What Factors Influenced Covid-19 Vaccine Hesitancy? Evidence From Social Media, Huseyin Zeyd Koytak
Population Health Research Brief Series
Vaccine hesitancy is one of the most significant threats to global public health efforts. Despite the rapid development and deployment of effective vaccines, resistance to vaccination has persisted in many communities, undermining collective immunity and prolonging health crises, including most recently the COVID-19 pandemic. This brief summarizes findings from a study that used data from over 50 million tweets (later rebranded as X) from 2020 to 2022 to investigate the patterns, justifications, and socioeconomic roots of vaccine hesitancy in the United States. The authors find that Twitter users in states with lower levels of education, higher poverty and unemployment rates, …
A Proposed Mhealth Intervention To Address Patient Barriers To Colposcopy Attendance: Qualitative Interview Study Of Clinic Staff And Patient Perspectives, Jennifer Hemler, Rachel Wagner, Brittany Sullivan, Myneka Macenat, Erin Tagai, Jazmarie Vega, Enrique Hernandez, Suzanne Miller, Kuang-Yi Wen, Charletta Ayers, Mark Einstein, Shawna Hudson, Racquel Kohler
A Proposed Mhealth Intervention To Address Patient Barriers To Colposcopy Attendance: Qualitative Interview Study Of Clinic Staff And Patient Perspectives, Jennifer Hemler, Rachel Wagner, Brittany Sullivan, Myneka Macenat, Erin Tagai, Jazmarie Vega, Enrique Hernandez, Suzanne Miller, Kuang-Yi Wen, Charletta Ayers, Mark Einstein, Shawna Hudson, Racquel Kohler
Department of Medical Oncology Faculty Papers
BACKGROUND: Cervical cancer disparities persist among minoritized women due to infrequent screening and poor follow-up. Structural and psychosocial barriers to following up with colposcopy are problematic for minoritized women. Evidence-based interventions using patient navigation and tailored telephone counseling, including the Tailored Communication for Cervical Cancer Risk (TC3), have modestly improved colposcopy attendance. However, the efficacious TC3 intervention is human resource-intense and could have greater reach if adapted for mobile health, which increases convenience and access to health information.
OBJECTIVE: This study aimed to describe feedback from clinic staff members involved in colposcopy processes and patients referred for colposcopy regarding adaptions …
Use Of Ai In Family Medicine Publications: A Joint Editorial From Journal Editors, Sarina Schrager, Dean A. Seehusen, Sumi M. Sexton, Caroline Richardson, Jon Neher, Nicholas Pimlott, Marjorie A. Bowman, José E. Rodríguez, Christopher P. Morley, Li Li, James Domdera
Use Of Ai In Family Medicine Publications: A Joint Editorial From Journal Editors, Sarina Schrager, Dean A. Seehusen, Sumi M. Sexton, Caroline Richardson, Jon Neher, Nicholas Pimlott, Marjorie A. Bowman, José E. Rodríguez, Christopher P. Morley, Li Li, James Domdera
Population and Public Health Sciences Faculty Publications
There are multiple guidelines from publishers and organizations on the use of Artificial Intelligence (AI) in publishing.1–5 However, none are specific to family medicine. Most journals have some basic AI use recommendations for authors, but more explicit direction is needed, as not all AI tools are the same.
Intravaginal Cooling Provides Symptom Relief In Women With Vulvovaginal Candidiasis And Reduces Immunopathology In An Accompanying Mouse Model, Junko Yano, Kimberly Langdon, Michael Swor, Mairi C. Noverr, Paul L. Fidel
Intravaginal Cooling Provides Symptom Relief In Women With Vulvovaginal Candidiasis And Reduces Immunopathology In An Accompanying Mouse Model, Junko Yano, Kimberly Langdon, Michael Swor, Mairi C. Noverr, Paul L. Fidel
School of Dentistry Faculty Publications
BACKGROUND: Vulvovaginal candidiasis (VVC), caused primarily by Candida albicans, is currently treated with either prescription or over-the-counter antifungal drugs, often with variable efficacy and relapses. New and improved therapeutic strategies, including drug-free treatment alternatives, are needed. Upon overgrowth or environmental triggers, C. albicans yeast transitions into hyphae that results in an aberrant immunopathologic response by neutrophils, contributing to the characteristic vulvovaginal symptoms. The purpose of this study was to evaluate the efficacy of a patented intravaginal cooling device (Vlisse®) to provide symptom relief in women with VVC via putative reversal of C. albicans hyphae to the commensal yeast form, with …
The Functional Fitness Of The Community Dwelling Older Adults In Shan Dong Of Mainland China In Comparison With The Population In Hong Kong, Zongtao Li, Yu Teng, Huigang Wang, Hao Liu, Lei Zhao
The Functional Fitness Of The Community Dwelling Older Adults In Shan Dong Of Mainland China In Comparison With The Population In Hong Kong, Zongtao Li, Yu Teng, Huigang Wang, Hao Liu, Lei Zhao
International Journal of Physical Activity and Health
Purpose: To compare the functional fitness (FF) of the community dwelling older adults in Shan Dong (SD) of mainland China with their peers in Hong Kong (HK). Methods: 1887 older adults living in SD were measured with Senior Fitness Test (SFT) One sample T test was used to determine the age grooup difference in each FF component between the population of SD and HK. Results: Compared with their HK peers, SD older adults showed higher performance in the task of 30s arm curl, but lower abilities in 30s chair stand, back scratch, chair sit & reach, and 8 ft …
Students' Perceived Value And Emotions In Turkish Physical Education: Testing Moderation By Gender And Sports Involvement, Mehmet Ceylan, Kelly L. Simonton
Students' Perceived Value And Emotions In Turkish Physical Education: Testing Moderation By Gender And Sports Involvement, Mehmet Ceylan, Kelly L. Simonton
International Journal of Physical Activity and Health
Physical Education (PE) has been recognized as a key element in developing student enjoyment for physical activity and healthy lifestyle habits. Student emotions may dictate learning and motivation, but less is known regarding the perceptions of value and control that shape these emotions. Specifically, within certain K-12 PE national curriculums and cultures, the goals and objectives of PE, along with its emphasis on physical activity and sport, may influence the emotional response of students and their perceived value of PE. If students feel a lack of value, negative emotions, and marginalized by the content then it is unlikely their experiences …
Mental Health Conditions Of Adults With Chronic Obstructive Pulmonary Disease And Comorbidities, Amanda M. Hinson-Enslin, Luis E. Espinoza, Jennifer L. Talleff
Mental Health Conditions Of Adults With Chronic Obstructive Pulmonary Disease And Comorbidities, Amanda M. Hinson-Enslin, Luis E. Espinoza, Jennifer L. Talleff
Journal of Social, Behavioral, and Health Sciences
Although the association is not well understood, people with COPD are likely to suffer from mental health issues such as depression and anxiety. Due to this occurrence, the aim of the present study is to better understand the mental health experience and COPD comorbidities of U.S. adults with a COPD diagnosis. The final sample comprised 1,676 U.S. adults who were surveyed in the 2019 National Health Interview Survey adult public file. Logistic and ordinal regression were used to calculate adjusted odds ratios for comorbid conditions predicting depression, anxiety, and the number of mental health issues, respectively. Depressive symptoms were more …
Evaluation Of Financial Risk Protection Provided By Private Health Insurance In Malaysia, Ng Rui Jie
Evaluation Of Financial Risk Protection Provided By Private Health Insurance In Malaysia, Ng Rui Jie
Student Works (2020-2029)
Private health insurance (PHI) has emerged as an alternative health financing option to public health financing, with the goal of achieving and maintaining universal health coverage. Despite its growing prominence, there is ongoing debate about the extent to which PHI contributes to financial risk protection. In Malaysia, the prevalence of PHI coverage has increased due to factors such as an expanding affluent demographic, government encouragement, and challenges in public healthcare delivery. However, there have been very limited studies assessing the financial risk protection provided by PHI in Malaysia, making this a critical gap that this research aims to address. To …
Uncovering The Binding Mechanism Of Mutated Omicron Variants Via Computational Strategies, Sajjad Haider, Nadeem Ahmad, Muhammad Shafiq, Ali Raza Siddiqui, Mohammad Nur-E-Alam, Aftab Ahmed, Zaheer Ul-Haq
Uncovering The Binding Mechanism Of Mutated Omicron Variants Via Computational Strategies, Sajjad Haider, Nadeem Ahmad, Muhammad Shafiq, Ali Raza Siddiqui, Mohammad Nur-E-Alam, Aftab Ahmed, Zaheer Ul-Haq
Pharmacy Faculty Articles and Research
The COVID-19 pandemic, triggered by the SARS-CoV-2 virus, has resulted in nearly 630 million cases and 6.60 million fatalities globally, as of November 2022. SARS-CoV-2, a species of the Coronaviridae family, has a single-stranded positive-sense RNA genome as well as four main structural proteins (S, E, M, and N) required for viral entrance into target cells. The spike protein (S) influences this entry through interactions with human angiotensin-converting enzyme 2 (hACE2) receptor. The World Health Organization (WHO) recognized numerous variants of concern (VOCs) that involve Alpha, Beta, Gamma, Delta, and Omicron, having multiple mutations within the spike protein, altering infection …
Greece And Harm Reduction Efficacy, Callie Wagers
Greece And Harm Reduction Efficacy, Callie Wagers
Posters-at-the-Capitol
An overview of the significance of harm reduction strategies in public health, highlighting Greece's innovative approaches recognized by the Healthy Cities Award. Harm reduction encompasses a range of policies and programs designed to minimize the negative health and social impacts associated with substance use, emphasizing pragmatic and compassionate solutions rather than punitive measures. Greece's successful initiatives—such as syringe exchange programs, supervised consumption sites, and comprehensive addiction treatment services—serve as a model for addressing public health crises. Kentucky, facing significant challenges related to substance use disorders, can adopt and adapt Greece's harm reduction methods to enhance the well-being of its communities. …
Dissecting The Binding Affinity Of Anti-Sars-Cov-2 Compounds To Human Transmembrane Protease, Serine 2: A Computational Study, Yue-Hui Shi, Jian-Xin Shen, Yan Tao, Yuan-Ling Xia, Zhi-Bi Zhang, Yun-Xin Fu, Ke-Qin Zhang, Shu-Qun Liu
Dissecting The Binding Affinity Of Anti-Sars-Cov-2 Compounds To Human Transmembrane Protease, Serine 2: A Computational Study, Yue-Hui Shi, Jian-Xin Shen, Yan Tao, Yuan-Ling Xia, Zhi-Bi Zhang, Yun-Xin Fu, Ke-Qin Zhang, Shu-Qun Liu
Faculty, Staff and Student Publications
The human transmembrane protease, serine 2 (TMPRSS2), essential for SARS-CoV-2 entry, is a key antiviral target. Here, we computationally profiled the TMPRSS2-binding affinities of 15 antiviral compounds. Molecular dynamics (MD) simulations for the docked complexes revealed that three compounds exited the substrate-binding cavity (SBC), suggesting noncompetitive inhibition. Of the remaining compounds, five charged ones exhibited reduced binding stability due to competing electrostatic interactions and increased solvent exposure, while seven neutral compounds showed stronger binding affinity driven by van der Waals (vdW) interactions compensating for unfavorable electrostatic effects (including electrostatic interactions and desolvation penalties). Positive and negative hotspot residues were identified …
Medicaid Expansion Increases Treatment For Patients With Colon Cancer, John Morgan Lyons, Denise M. Danos, Lauren S. Maniscalco, Yong Yi, Omeed Moaven, Xiaocheng Wu, Quyen Chu
Medicaid Expansion Increases Treatment For Patients With Colon Cancer, John Morgan Lyons, Denise M. Danos, Lauren S. Maniscalco, Yong Yi, Omeed Moaven, Xiaocheng Wu, Quyen Chu
School of Medicine Faculty Publications
Introduction: Medicaid expansion (ME) has positively impacted colon cancer screening. ME’s effect on colon cancer treatment is less clear. This study analyses the effect of ME on patterns of colon cancer treatment. Methods: Patients with primary invasive colon cancer were identified using the Louisiana Tumor Registry. Patients diagnosed with colon cancer prior to ME (2014–2015) were compared to those diagnosed after (2017–2018). Coordinate variables were analyzed using Fisher’s exact test. Treatment status was modeled with multivariable logistic regression and the results are reported as adjusted odds ratios. Results: The proportion of uninsured patients decreased following ME (5.5 versus 1.9, p < 0.001), with the greatest reductions among patients between 45 and 54 years old (13.5% to 3.5%, p < 0.0001), African Americans (8.9 to 2.1%, p < 0.0001), and those in high-poverty neighborhoods (7.1 to 2.1%, p < 0.0001). Following ME, all patients with Stage I-III disease were more likely to receive surgery (OR = 1.95; 95%: CI 1.21–3.14)—especially the extremely impoverished (OR = 2.39; 95% CI 1.41–4.02). Young patients with Stage IV colon cancer were more likely to receive chemotherapy (OR-1.6; 95% CI 1.03–2.4). Patients with Stage IV colon cancer were less likely to receive treatment within 30 days of diagnosis (OR = 0.7; 95% CI 0.5–0.9), but, on subset analysis, this was only observed in non-Medicaid patients. Conclusion: ME is associated with increased treatment for patients with colon cancer, and it did not appear to affect time to treatment. However, it seems to affect different subsets of the population differently.
Residual Traditional Risk In Non-Traditional Atherosclerotic Diseases, Federico Biscetti, Giorgia Polito, Maria Margherita Rando, Maria Anna Nicolazzi, Luis H. Eraso, Paul J. Dimuzio, Massimo Massetti, Antonio Gasbarrini, Andrea Flex
Residual Traditional Risk In Non-Traditional Atherosclerotic Diseases, Federico Biscetti, Giorgia Polito, Maria Margherita Rando, Maria Anna Nicolazzi, Luis H. Eraso, Paul J. Dimuzio, Massimo Massetti, Antonio Gasbarrini, Andrea Flex
Department of Surgery Faculty Papers
Individuals with chronic inflammatory and immune disorders are at an increased risk of atherosclerotic events and premature cardiovascular (CV) disease. Despite extensive literature exploring the relationship between "non-traditional" atherosclerotic conditions and CV risk, many aspects remain unresolved, including the underlying mechanisms promoting the "non-traditional CV risk", the development of an innovative and comprehensive CV risk assessment tool, and recommendations for tailored interventions. This review aims to evaluate the available evidence on key "non-traditional" CV risk-enhancer conditions, with a focus on assessing and managing CV risk factors. We conducted a comprehensive review of 412 original articles, narrative and systematic reviews, and …
Lessons Learned From The Covid-19 Pandemic Crisis Management In The Gaza Strip: A Qualitative Study., Belal Aljamal
Lessons Learned From The Covid-19 Pandemic Crisis Management In The Gaza Strip: A Qualitative Study., Belal Aljamal
Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث
Aims of the study: The main aim of this study was to discover the lessons learned from the COVID-19 pandemic crisis management from health policymakers' perspective in the Gaza Strip. Methods: The researcher used a qualitative design, targeting 25health policymakers using a purposeful sampling technique and face-to-face semi-structured interviews to collect data. To analyze the interview data, the directed qualitative content analysis approach was used.
Results: All interviewees agreed that the Palestinian Ministry of Health (MoH) managed the COVID-19pandemic well despite the insufficient resources and lack of experience. More specifically, the average of most participants’ assessments of Palestinian MoH “Preparedness” …
'A Little Knowledge Is A Dangerous Thing': Rural Realities, Professional Ideals, And The Forgotten History Of Cottage Nursing C. 1880-1939, Martha Groppo
EKU Faculty and Staff Scholarship
This paper examines the rise and fall of cottage nursing, a controversial approach to rural healthcare that was championed across the United Kingdom from the 1880s to the interwar period. Defying the strategies being used to professionalise nursing in urban centres, cottage nursing supporters argued that nurses for the rural poor should be recruited from the lowest social classes, given only the briefest training, and prepared to do both nursing and menial domestic work. Their critics espoused the noble ideal of providing the rural poor with only the best-trained lady district nurses from the apparent moral high ground, persuasively arguing …
Temporal Trends And Patterns For Early- And Late-Onset Adult Liver Cancer Incidence Vary By Race/Ethnicity, Subsite, And Histologic Type In The United States From 2000 To 2019, Mei-Chin Hsieh, Kendra L. Ratnapradipa, Laura Rozek, Shengdi Wen, Yu Wen Chiu, Edward S. Peters
Temporal Trends And Patterns For Early- And Late-Onset Adult Liver Cancer Incidence Vary By Race/Ethnicity, Subsite, And Histologic Type In The United States From 2000 To 2019, Mei-Chin Hsieh, Kendra L. Ratnapradipa, Laura Rozek, Shengdi Wen, Yu Wen Chiu, Edward S. Peters
School of Public Health Faculty Publications
Purpose: To examine incidence trends and patterns for early- and late-onset liver cancer. Methods: Liver and intrahepatic bile duct (IBD) cancers diagnosed between 2000 and 2019 were acquired from 22 SEER registries. Variables included early-onset (20–49) vs. late-onset (50+), anatomic subsite, histologic type (hepatocellular carcinoma [HCC] and IBD cholangiocarcinoma [ICC]), sex, and race/ethnicity. Age-standardized incidence rates were calculated using SEER*Stat. Jointpoint regression analysis was employed to estimate the annual percent change (APC) and the average APC (AAPC) with pairwise comparisons for trend by sex and by race/ethnicity stratified by age and subsite. Results: Liver cancer incidence decreased among early-onset (AAPC …
Genome-Wide Association Study Reveals Shared And Distinct Genetic Architecture Of Fatty Acids And Oxylipins In The Hispanic Community Health Study/Study Of Latinos, Carolina G Downie, Heather M Highland, Mona Alotaibi, Barrett M Welch, Annie Green Howard, Susan Cheng, Nick Miller, Mohit Jain, Robert C Kaplan, Adam G Lilly, Tao Long, Tamar Sofer, Bharat Thyagarajan, Bing Yu, Kari E North, Christy L Avery
Genome-Wide Association Study Reveals Shared And Distinct Genetic Architecture Of Fatty Acids And Oxylipins In The Hispanic Community Health Study/Study Of Latinos, Carolina G Downie, Heather M Highland, Mona Alotaibi, Barrett M Welch, Annie Green Howard, Susan Cheng, Nick Miller, Mohit Jain, Robert C Kaplan, Adam G Lilly, Tao Long, Tamar Sofer, Bharat Thyagarajan, Bing Yu, Kari E North, Christy L Avery
Faculty, Staff and Student Publications
Bioactive fatty acid-derived oxylipin molecules play key roles mediating inflammation and oxidative stress. Circulating levels of fatty acids and oxylipins are influenced by environmental and genetic factors; characterizing the genetic architecture of bioactive lipids could yield new insights into underlying biology. We performed a genome-wide association study (GWAS) of 81 fatty acids and oxylipins in 11,584 Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants with genetic and lipidomic data measured at study baseline (58.6% female, mean age = 46.1 years (standard deviation 13.8)). Additionally, given the effects of central obesity on inflammation, we examined interactions with waist circumference using two-degree-of-freedom …
Nourishing Change In Houston, Texas: Exploring Grocery Shopping Behaviours And Fruit And Vegetable Consumption Among Low-Income Families In The Brighter Bites Program, Victoria Kwentua, Allison Marshall, Ru-Jye Chuang, Jessica Chen, Christine Markham, Mallika Mathur, Mike Pomeroy, Megan Hall, Shreela Sharma
Nourishing Change In Houston, Texas: Exploring Grocery Shopping Behaviours And Fruit And Vegetable Consumption Among Low-Income Families In The Brighter Bites Program, Victoria Kwentua, Allison Marshall, Ru-Jye Chuang, Jessica Chen, Christine Markham, Mallika Mathur, Mike Pomeroy, Megan Hall, Shreela Sharma
Faculty, Staff and Student Publications
OBJECTIVE: We qualitatively examine the grocery shopping behaviours and fruit and vegetable consumption of low-income families participating in the Brighter Bites program in Houston, Texas.
DESIGN: We used a single-group observational study design. We used (1) purposive sampling of schools and (2) convenience sampling of parents/caregivers to recruit participants. Research staff conducted three face-to-face qualitative focus groups in Spanish and English. Transcripts were coded using deductive and inductive reasoning.
SETTING: Three elementary schools serving low-income families in Houston, Texas, in February-May of 2022.
PARTICIPANTS: Brighter Bites parents/caregivers from the 2021-2022 school year.
RESULTS: Three primary themes emerged: (1) child involvement …
Customized Feminine Hygiene Wash Containing Postbiotics From Lactobacillus Spp. To Treat Urinary Tract Infections (Uti), Veena G. Nair
Customized Feminine Hygiene Wash Containing Postbiotics From Lactobacillus Spp. To Treat Urinary Tract Infections (Uti), Veena G. Nair
Theses and Dissertations
Probiotics, which support host health by maintaining normal microbial flora, offer a promising approach for preventing recurrent infections. To evaluate the prophylactic potential of vaginal probiotics against urinary tract infections (UTIs), we conducted a study on 54 healthy South Indian women aged 18–40 who visited the Obstetrics and Gynaecology outpatient clinic at Trichy SRM Medical College and Research Centre between June and July 2022. Vaginal swabs were collected following ethical guidelines, and commensal microbiota were isolated for probiotic characterization, with the broader objective of developing a customized feminine hygiene wash enriched with vaginal postbiotics.
Lactobacilli cell-free supernatant (CFS) demonstrated potent …
Application Of Core Functions And Forms In Complex Health Intervention Research: A Scoping Review Protocol, Katelyn Fox, Debbie Passey, Eunyoung Kang, Laura Zeigen, Erin Kenzie, Jessica D Austin, Rachel J Meadows, Maria E Fernandez, Monica Perez Jolles
Application Of Core Functions And Forms In Complex Health Intervention Research: A Scoping Review Protocol, Katelyn Fox, Debbie Passey, Eunyoung Kang, Laura Zeigen, Erin Kenzie, Jessica D Austin, Rachel J Meadows, Maria E Fernandez, Monica Perez Jolles
Faculty, Staff and Student Publications
Introduction: The ability of healthcare, community and public health systems to effectively implement and disseminate research innovations depends on contextual factors at multiple interconnected levels of influence (eg, the innovation, individual, provider/implementor, organisation and health system). Recently, there has been an increase in the development of complex interventions designed to target multiple levels, designed for or adapted to the context in which they are delivered. Two concepts from complex systems thinking have been increasingly used to operationalise such interventions-core functions (theory and evidence-driven purposes of interventions) and forms (adaptable activities that perform each core function). However, there is a gap …
Exploring The Lived Experiences Of Persons Living With Hiv Who Are Homebound Due To One Or More Comorbidities Within A Southern State Using Photovoice, Anthony Alyn "Deek" Cunningham
Exploring The Lived Experiences Of Persons Living With Hiv Who Are Homebound Due To One Or More Comorbidities Within A Southern State Using Photovoice, Anthony Alyn "Deek" Cunningham
All ETDs from UAB
At the end of 2022, there were 1,109,418 adults and adolescents with HIV in the United States and the six dependent areas of American Samoa, Guam, the Northern Mariana Islands, Puerto Rico, the Republic of Palau, and the US Virgin Islands (CDC, 2024). Due to ongoing advances in medications and treatments, people who have been diagnosed with HIV are living longer and healthier lives, making this a chronic health condition. Yet, there are gaps in the literature that focuses on this population growing older and aging in place. This dissertation investigated the lived experiences of individuals fifty years and older …
Toward Personalized Digital Experiences To Promote Diabetes Self-Management: Mixed Methods Social Computing Approach, Tavleen Singh, Kirk Roberts, Kayo Fujimoto, Jing Wang, Constance Johnson, Sahiti Myneni
Toward Personalized Digital Experiences To Promote Diabetes Self-Management: Mixed Methods Social Computing Approach, Tavleen Singh, Kirk Roberts, Kayo Fujimoto, Jing Wang, Constance Johnson, Sahiti Myneni
Faculty, Staff and Student Publications
BACKGROUND: Type 2 diabetes affects nearly 34.2 million adults and is the seventh leading cause of death in the United States. Digital health communities have emerged as avenues to provide social support to individuals engaging in diabetes self-management (DSM). The analysis of digital peer interactions and social connections can improve our understanding of the factors underlying behavior change, which can inform the development of personalized DSM interventions.
OBJECTIVE: Our objective is to apply our methodology using a mixed methods approach to (1) characterize the role of context-specific social influence patterns in DSM and (2) derive interventional targets that enhance individual …