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Articles 1351 - 1380 of 55710
Full-Text Articles in Entire DC Network
Clinical, Imaging And Blood Biomarker Outcomes In A Phase 3 Clinical Trial Of Tau Aggregation Inhibitor Hydromethylthionine Mesylate In Mild Cognitive Impairment And Mild To Moderate Dementia Due To Alzheimer’S Disease, Claude Wischik, Richard G. Stefanacci, Peter Bentham, Serge Gauthier, Henrik Zetterberg, Gordon Wilcock, Lutz Froelich, Alistair Burns, Emer Macsweeney, Clive Ballard, Jin-Tai Yu, Tay Siew Choon, Vahe Asvatourian, Natalia Muehlemann, Jan Priel, Karin Kook, Tenecia Sullivan, Diane Downie, Sonya Miller, Carol Pringle, John Storey, Tom Baddeley, Charles R Harrington, Lewis Penny, Mohammad Arastoo, Roger Staff, Anca-Larisa Sandu, Helen Shiells, Serena Lo, Nafeesa Nazlee, Emily Evans, Claire Hull, Bjoern Schelter
Clinical, Imaging And Blood Biomarker Outcomes In A Phase 3 Clinical Trial Of Tau Aggregation Inhibitor Hydromethylthionine Mesylate In Mild Cognitive Impairment And Mild To Moderate Dementia Due To Alzheimer’S Disease, Claude Wischik, Richard G. Stefanacci, Peter Bentham, Serge Gauthier, Henrik Zetterberg, Gordon Wilcock, Lutz Froelich, Alistair Burns, Emer Macsweeney, Clive Ballard, Jin-Tai Yu, Tay Siew Choon, Vahe Asvatourian, Natalia Muehlemann, Jan Priel, Karin Kook, Tenecia Sullivan, Diane Downie, Sonya Miller, Carol Pringle, John Storey, Tom Baddeley, Charles R Harrington, Lewis Penny, Mohammad Arastoo, Roger Staff, Anca-Larisa Sandu, Helen Shiells, Serena Lo, Nafeesa Nazlee, Emily Evans, Claire Hull, Bjoern Schelter
College of Population Health Faculty Papers
BACKGROUND: Hydromethylthionine mesylate (HMTM) targets tau pathology and has tau-independent symptomatic activity.
OBJECTIVES: To evaluate the safety and efficacy of HMTM in participants with mild cognitive impairment (MCI) and mild to moderate dementia due to Alzheimer's disease (AD).
SETTING: 82 centres in Canada, European Union, United Kingdom and United States of America.
PARTICIPANTS: A total of 598 amyloid β-PET positive participants were included; 44% (263) met clinical criteria for MCI due to Alzheimer's disease and 56% (335) were diagnosed with mild to moderate dementia due to AD.
INTERVENTION: HMTM 16 mg/day and 8 mg/day were compared with methylthioninium chloride (MTC) …
Dietary Inflammatory Index And Risk Of Colorectal Cancer In Japanese Men, Ayaka Kotemori, Kumiko Kito, Motoki Iwasaki, Taiki Yamaji, James Hébert Scd, Junko Ishihara, Manami Inoue, Shoichiro Tsugane, Norie Sawada On The Behalf Of Jphc Study Group
Dietary Inflammatory Index And Risk Of Colorectal Cancer In Japanese Men, Ayaka Kotemori, Kumiko Kito, Motoki Iwasaki, Taiki Yamaji, James Hébert Scd, Junko Ishihara, Manami Inoue, Shoichiro Tsugane, Norie Sawada On The Behalf Of Jphc Study Group
Faculty Publications
Background/Objectives: Unhealthy lifestyles lead to chronic low-grade inflammation, increasing the risk of colorectal cancer. Few studies in East Asia have examined the association between the dietary inflammation potential and colorectal cancer incidence. Therefore, we aimed to investigate this association further in the Japanese population. Methods: This study included 38,807 men aged 45–74 years who participated in the Japan Public Health Center-based prospective study (JPHC Study). The energy-adjusted dietary inflammatory index (E-DII) was derived from a food frequency questionnaire. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox proportional hazards regression models. Differences in risk due to a …
Metabolome Contribution To Sex Differences In The Link Between Alcohol Consumption And Type 2 Diabetes: A Prospective Analysis In The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Brian Wang, Kai Luo, Wenyan Ma, Yanbo Zhang, Christina Cordero, Amber Pirzada, Martha Daviglus, Krista M Perreira, Bing Yu, Eric Boerwinkle, Robert C Kaplan, Qibin Qi
Metabolome Contribution To Sex Differences In The Link Between Alcohol Consumption And Type 2 Diabetes: A Prospective Analysis In The Hispanic Community Health Study/Study Of Latinos (Hchs/Sol), Brian Wang, Kai Luo, Wenyan Ma, Yanbo Zhang, Christina Cordero, Amber Pirzada, Martha Daviglus, Krista M Perreira, Bing Yu, Eric Boerwinkle, Robert C Kaplan, Qibin Qi
Faculty, Staff and Student Publications
Background: Light-to-moderate alcohol consumption has been linked to improved insulin resistance and lower type 2 diabetes (T2D) risk predominantly in females but not males. Potential mechanisms underlying this sex difference remain unclear.
Objective: This study evaluated associations of sex-specific alcohol-associated metabolomic signatures (AMSs) with insulin resistance and T2D risk in US Hispanic/Latino adults.
Methods: We analyzed serum metabolome data in the HCHS/SOL, a prospective, multicenter, community-based study of Hispanics/Latinos, aged 18 to 74 years old, enrolled from four U.S. metropolitan areas between 2008 and 2011. Sex-specific AMSs were developed using Elastic Net to identify serum metabolites uniquely associated with alcohol …
Postdischarge Pediatric Mortality In Nigeria For Children Under 5 Years Of Age, Philomina Nwaugo Chukwudike
Postdischarge Pediatric Mortality In Nigeria For Children Under 5 Years Of Age, Philomina Nwaugo Chukwudike
Walden Dissertations and Doctoral Studies
Child mortality has remained a public health issue that is prevalent among families living in Nigeria and low- and middle-income countries. Factors associated with post-discharge pediatric mortality among children under 5 have not been explored. The study involved examining associations between timely individual follow-up visits, availability of healthcare facilities for follow-up care, and likelihood of post-discharge mortality among children under 5 while adjusting for household income, geographical location, mothers’ age, and mothers’ education. The theoretical framework was the social ecological model. Data were generated from the 2018 Demographic and Health Survey. A sample size of N=21,671 was used to determine …
Long-Term Mpox Sequelae 11 To 18 Months After Acute Illness : A Cohort Study In Two Us Cities, Preetam A Cholli, Jason Zucker, Karen J Vigil, Faisal S Minhaj, Paul J Weidle, Melanie M Taylor, Brett Gray, Dana L Haberling, Agha Ajmal, Agam K Rao, Anyelina Cantos, Sarah Anne J Guagliardo, Max Flanagan, Gilhen H Rodriguez, Irene Tamí-Maury, Siobhán M O'Connor
Long-Term Mpox Sequelae 11 To 18 Months After Acute Illness : A Cohort Study In Two Us Cities, Preetam A Cholli, Jason Zucker, Karen J Vigil, Faisal S Minhaj, Paul J Weidle, Melanie M Taylor, Brett Gray, Dana L Haberling, Agha Ajmal, Agam K Rao, Anyelina Cantos, Sarah Anne J Guagliardo, Max Flanagan, Gilhen H Rodriguez, Irene Tamí-Maury, Siobhán M O'Connor
Faculty, Staff and Student Publications
Background: Little was known about persistent sequelae of mpox before the 2022 multinational clade II mpox virus outbreak.
Objective: To characterize post-mpox sequelae 11 to 18 months after acute mpox diagnosis and compare outbreak-associated psychosocial and behavioral impact between at-risk persons who had or did not have mpox.
Design: Cohort study.
Setting: New York City, New York, and Houston, Texas.
Participants: Adults attending HIV, pre-exposure prophylaxis, or sexually transmitted infection clinics diagnosed with mpox during May 2022 to January 2023 (post-mpox) or at risk for but never diagnosed with mpox (no-mpox).
Measurements: All participants completed psychosocial and behavioral self-assessments. A …
Evaluating The Dispensing Of Non-Prescription Antibiotics In Baghdad's Community Pharmacies: A Public Health Concern., Ali Azeez Ali Al-Jumaili, Yusr Burhan Ahmed, Hasan Ali Hasan Shubbar, Mina Mohammed Jabbar
Evaluating The Dispensing Of Non-Prescription Antibiotics In Baghdad's Community Pharmacies: A Public Health Concern., Ali Azeez Ali Al-Jumaili, Yusr Burhan Ahmed, Hasan Ali Hasan Shubbar, Mina Mohammed Jabbar
Maaen Journal for Medical Sciences
Background: Despite existing regulatory restrictions from the Iraqi Ministry of Health and global guidance from the World Health Organization, the practice of dispensing antibiotics without prescriptions remains prevalent.
Objectives: This study aimed to assess the prevalence of non-prescription antibiotic dispensing in community pharmacies across Iraq and to evaluate pharmacy personnel’s perceptions and practices concerning antimicrobial use.
Methods: A cross-sectional survey was conducted between January and February 2025, targeting 63 pharmacists working in independent pharmacies across Baghdad and other Iraqi governorates. Data were obtained through a predefined questionnaire administered both in person and online. Descriptive statistics summarized participant demographics and responses, …
Pesticides Associated With Incident Diabetes Among Licensed Private Pesticide Applicators In The Agricultural Health Study Cohort (1993–2021), Christine G Parks, Qian Xiao, Jesse Wilkerson, Jonathan N Hofmann, Laura E Beane Freeman, Dale P Sandler
Pesticides Associated With Incident Diabetes Among Licensed Private Pesticide Applicators In The Agricultural Health Study Cohort (1993–2021), Christine G Parks, Qian Xiao, Jesse Wilkerson, Jonathan N Hofmann, Laura E Beane Freeman, Dale P Sandler
Faculty, Staff and Student Publications
Background: Growing evidence suggests pesticides may increase risk of type 2 diabetes, but data are limited on many specific chemicals.
Methods: In 29,527 private pesticide applicators in the Agricultural Health Study cohort (enrolled 1993-1997 in Iowa and North Carolina), 3,847 incident diabetes cases were identified by self-report during follow-up surveys in 1999-2003, 2005-2010, 2013-2015, and 2019-2021. We examined 50 pesticides reported at enrollment, updated in 1999-2003 or 2005-2010, prior to diabetes diagnosis or end of follow-up, using log-binomial regression to calculate relative risks (RR) and 95% confidence intervals (CI) for ever-use and intensity-weighted lifetime days (IWLD) use (tertiles, T1-3), adjusting …
Plans4care, A Web Application Providing Caregivers Personalized Solutions To Manage Dementia-Related Care Challenges: Proof Of Concept And Efficacy Trial, Laura N. Gitlin, Eric Jutkowitz, Catherine V. Piersol, Sokha Koeuth, Taylor Sivori, Melinda J. Webster, Rachel N. Barnett, David L. Roth
Plans4care, A Web Application Providing Caregivers Personalized Solutions To Manage Dementia-Related Care Challenges: Proof Of Concept And Efficacy Trial, Laura N. Gitlin, Eric Jutkowitz, Catherine V. Piersol, Sokha Koeuth, Taylor Sivori, Melinda J. Webster, Rachel N. Barnett, David L. Roth
Department of Occupational Therapy Faculty Papers
OBJECTIVE: Few dementia caregivers have access to evidence-based support programs. Web applications (app) may address this gap. Plans4Care, a web app, provides caregivers with on-demand personalized solutions to address care challenges. We present results of a proof-of-concept study and describe a trial protocol to test efficacy.
METHODS: To use Plans4Care, caregivers respond to brief onboarding questions, assess dementia patients' cognitive function, identify care challenges, and generate "action plans" (personalized strategies). Telehealth sessions with dementia-trained care advisors are available. A proof-of-concept study evaluated a clickable prototype using standardized technology scales to determine if >75 % scored positively on four criteria (acceptability, …
Forecasting (Nano)Medical Technologies: Lessons From The Covid-19 Pandemic For Science And Society, Vuk Uskoković
Forecasting (Nano)Medical Technologies: Lessons From The Covid-19 Pandemic For Science And Society, Vuk Uskoković
Administration and Staff Articles and Research
Successful translation of medical devices from the bench to the bedside is conditioned by the accurate estimation of market opportunities. Because market conditions can change significantly over time, this assessment is challenging in the early stages of technological development. In this study a qualitative analysis of market trends and regulatory frameworks was conducted to assess how transient market conditions influence the development and distribution of nanomedical technologies, using nanotechnologies developed for COVID-19 as the example. The findings demonstrate that the unpredictable nature of the COVID-19 pandemic has led to a volatile market for nanomedical solutions, discouraging private sector investment and …
Reducing Work-Related Screen-Time In Healthcare Workers During Leisure Time (Reduce Screen) - A Randomized Controlled Trial, Karsten Bartels, Karan Shah, Emelind Sanchez Rodriguez, Julie T Hoffman, Megan L Rolfzen, Juana Mora Valdovinos, Afton L Hassett, Daniel I Sessler
Reducing Work-Related Screen-Time In Healthcare Workers During Leisure Time (Reduce Screen) - A Randomized Controlled Trial, Karsten Bartels, Karan Shah, Emelind Sanchez Rodriguez, Julie T Hoffman, Megan L Rolfzen, Juana Mora Valdovinos, Afton L Hassett, Daniel I Sessler
Faculty, Staff and Student Publications
The ubiquitous availability of work-related applications on personal devices makes healthcare workers prone to working during leisure time. We tested the hypothesis that an intervention to reduce work-related screen time during a weekend off reduces stress in healthcare workers in a pragmatic parallel design randomized controlled trial between November 2021 and November 2023. Healthcare workers using a smartphone with a work email application were eligible. Randomization was 1:1 to no treatment or a threefold educational intervention to: 1) activate automated responses to emails received, 2) reduce screen time, and 3) uninstall work applications from personal devices. The primary outcome was …
Reflection Paper: What We Make Together: Art, Adolescence, And Collaborative Research In Action, Natepy Vann
Reflection Paper: What We Make Together: Art, Adolescence, And Collaborative Research In Action, Natepy Vann
Introduction to Public Health
No abstract provided.
Peace Innovation And Healing: A Design Justice Framework To Support Change Processes, Strengthen Relationships, Foster Trust, And Build Community, Michelle Helman
Peace Innovation And Healing: A Design Justice Framework To Support Change Processes, Strengthen Relationships, Foster Trust, And Build Community, Michelle Helman
Peace and Conflict Studies Journal Conference
Many organizations aiming to achieve peace and health equity outcomes often focus their design processes and innovation efforts externally without addressing how their organizational culture can unintentionally reproduce the very harms they are trying to address. The purpose of this qualitative design research study is to explore the role of a design justice framework in piloting a Peace Innovation Project aimed at facilitating an organizational culture change process. Specifically, the study focuses on better understanding how integrating a design justice approach could support research collaborators to center equity and justice as core components in building a culture of peace and …
Embodying Design Justice: A Peace Education Framework To Strengthen Relationships, Foster Trust And Build Community, Michelle Helman
Embodying Design Justice: A Peace Education Framework To Strengthen Relationships, Foster Trust And Build Community, Michelle Helman
Peace and Conflict Studies Journal Conference
BACKGROUND
Groups working toward creating peace and equity often focus on external innovation without addressing internal culture shifts necessary to navigate change and achieve their goals. Michelle’s doctoral research and practice address this challenge through a design research study and peace innovation project focused on organizational culture transformation through a design justice framework. Findings suggest that interweaving the framework with storytelling, arts, and embodiment practices are key to support people in navigating change processes to strengthen relationships, foster trust, and build community.
ABOUT
The workshop offers an applied learning experience for participants to explore the concepts of design and innovation …
Whole Genome Sequence Analysis Of Pulmonary Function And Copd In 44,287 Multi-Ancestry Participants, Wonji Kim, Xiaowei Hu, Kangjin Kim, Sung Chun, Peter Orchard, Dandi Qiao, Ingo Ruczinski, Aabida Saferali, Francois Aguet, Lucinda Antonacci-Fulton, Pallavi P Balte, Traci M Bartz, Wardatul Jannat Anamika, Xiaobo Zhou, Junyi Duan, Jennifer A Brody, Brian E Cade, Martha L Daviglus, Harshavadran Doddapaneni, Shannon Dugan-Perez, Susan K Dutcher, Christian D Frazar, Stacey B Gabriel, Sina A Gharib, Namrata Gupta, Brian D Hobbs, Silva Kasela, Laura R Loehr, Ginger A Metcalf, Donna M Muzny, Elizabeth C Oelsner, Laura J Rasmussen-Torvik, Colleen M Sitlani, Joshua Smith, Tamar Sofer, Hanfei Xu, Bing Yu, David Zhang, John Ziniti, R Graham Barr, April P Carson, Myriam Fornage, Lifang Hou, Ravi Kalhan, Robert Kaplan, Tuuli Lappalainen, Stephanie J London, Alanna C Morrison, George T O'Connor, Bruce M Psaty, Laura M Raffield, Susan Redline, Stephen S Rich, Jerome I Rotter, Edwin K Silverman, Ani Manichaikul, Michael H Cho
Whole Genome Sequence Analysis Of Pulmonary Function And Copd In 44,287 Multi-Ancestry Participants, Wonji Kim, Xiaowei Hu, Kangjin Kim, Sung Chun, Peter Orchard, Dandi Qiao, Ingo Ruczinski, Aabida Saferali, Francois Aguet, Lucinda Antonacci-Fulton, Pallavi P Balte, Traci M Bartz, Wardatul Jannat Anamika, Xiaobo Zhou, Junyi Duan, Jennifer A Brody, Brian E Cade, Martha L Daviglus, Harshavadran Doddapaneni, Shannon Dugan-Perez, Susan K Dutcher, Christian D Frazar, Stacey B Gabriel, Sina A Gharib, Namrata Gupta, Brian D Hobbs, Silva Kasela, Laura R Loehr, Ginger A Metcalf, Donna M Muzny, Elizabeth C Oelsner, Laura J Rasmussen-Torvik, Colleen M Sitlani, Joshua Smith, Tamar Sofer, Hanfei Xu, Bing Yu, David Zhang, John Ziniti, R Graham Barr, April P Carson, Myriam Fornage, Lifang Hou, Ravi Kalhan, Robert Kaplan, Tuuli Lappalainen, Stephanie J London, Alanna C Morrison, George T O'Connor, Bruce M Psaty, Laura M Raffield, Susan Redline, Stephen S Rich, Jerome I Rotter, Edwin K Silverman, Ani Manichaikul, Michael H Cho
Faculty, Staff and Student Publications
Background: Whole genome sequence (WGS) data in multi-ancestry samples supports discovery of low-frequency or population-specific genetic variants associated with chronic obstructive pulmonary disease (COPD) and lung function.
Results: We performed single variant, structural variant, and gene-based analysis of pulmonary function (FEV1, FVC and FEV1/FVC) and COPD case-control status in 44,287 multi-ancestry participants from the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program. We validated findings using the UK Biobank and assessed implicated genes using lung single-cell RNA-seq (scRNA-seq) data sets. Applying a genome-wide significance threshold (P < 5 × 10-9), we replicated known loci and identified novel associations near LY86, MAGI1, GRK7, and LINC02668. Colocalization with gene expression quantitative trait loci (eQTL) from the Lung Tissue Research Consortium highlighted known candidate genes including ADAM19, THSD4, C4B, and PSMA4, which were not identified through other eQTL sources. Multi-ancestry analysis improved fine-mapping resolution (e.g., HTR4 and RIN3). Gene-based analysis identified and replicated HMCN1. In human lung scRNA-seq data sets, lung epithelial cells and immune cell types showed enriched expression, while fibroblasts showed higher expression for HMCN1. CRISPR targeting HMCN1 in IMR90 demonstrated reduced expression of collagen genes.
Conclusions: Large-scale multi-ancestry WGS analysis improves variant discovery and fine-mapping resolution for lung function and …
Socioecological Stressors During Covid-19 Among Urban Refugee Youth In Kampala, Uganda: A Qualitative Descriptive Analysis, Sikky Shiqi Chen, Carmen H. Logie, Frannie Mackenzie, Moses Okumu, Robert Hakiza, Brenda Katisi, Daniel Kibuuka Musoke, Aidah Nakitende, Isha Berry, Bay Bahri, Peter Kyambadde
Socioecological Stressors During Covid-19 Among Urban Refugee Youth In Kampala, Uganda: A Qualitative Descriptive Analysis, Sikky Shiqi Chen, Carmen H. Logie, Frannie Mackenzie, Moses Okumu, Robert Hakiza, Brenda Katisi, Daniel Kibuuka Musoke, Aidah Nakitende, Isha Berry, Bay Bahri, Peter Kyambadde
Journal of Social, Behavioral, and Health Sciences
Limited studies have examined pandemic-related stressors among urban refugee youth in low and middle-income humanitarian countries (LMICs), such as Uganda. We explored the lived experience of COVID-19-related stressors among urban refugee youth in Kampala, Uganda. We analyzed qualitative data (text messages, WhatsApp chats, photos) collected in an interactive mobile health intervention with 346 refugee youth aged 16–24 in Kampala. Findings revealed stressors across socioecological levels: individual (e.g., financial-related distress), social (e.g., limited social interactions), community (e.g., food insecurity), and policy (e.g., unprecedented lockdowns). Findings can inform social work organization pandemic preparedness strategies for economic empowerment and social cohesion with youth.
Development Of The Self-Administered Health Complexity Screening Instrument, Sheila Specker, Rachel Andrew, Emily Drexler, Emily Koithan, Steven Thurber, Steven Frankel
Development Of The Self-Administered Health Complexity Screening Instrument, Sheila Specker, Rachel Andrew, Emily Drexler, Emily Koithan, Steven Thurber, Steven Frankel
School of Medicine Faculty Publications
PURPOSE: The purpose of the study was to develop a self-administered screening tool to assist case managers, primary care physicians, and other clinicians in quickly and accurately identifying patients with complex health needs who require a definitive and detailed case management evaluation. In addition to medical and psychiatric items, this tool incorporates multiple social determinants of health (SDOH), known to add to clinical complexity. PRIMARY PRACTICE SETTING: This instrument is most appropriate for identifying patients with high complexity in the primary care sector. Due to the abundance of such patients with high biopsychosocial complexity and costs of treating these patients, …
Rab5c Increases Endothelial Release Of Vwf By Regulating Vesicle Trafficking, Paula Reventun, Pablo Toledano-Sanz, Maria Delgado-Marin, Maria Viskadourou, D Brian Foster, Paul S De Vries, Maria Sabater-Lleal, Nunzio Alcharani, Claudia Gonzalez-Cucharero, William O Osburn, Alanna C Morrison, Alisa S Wolberg, Nicholas L Smith, Marios Arvanitis, Charles J Lowenstein
Rab5c Increases Endothelial Release Of Vwf By Regulating Vesicle Trafficking, Paula Reventun, Pablo Toledano-Sanz, Maria Delgado-Marin, Maria Viskadourou, D Brian Foster, Paul S De Vries, Maria Sabater-Lleal, Nunzio Alcharani, Claudia Gonzalez-Cucharero, William O Osburn, Alanna C Morrison, Alisa S Wolberg, Nicholas L Smith, Marios Arvanitis, Charles J Lowenstein
Faculty, Staff and Student Publications
Background: Abnormal levels of VWF (von Willebrand Factor) are a risk factor for venous thromboembolism (VTE) and bleeding. Genome-wide association studies for VWF have identified novel candidate genes that may regulate VWF levels in humans, including RAB5C (RAS-associated protein RAB5C). We hypothesized that RAB5C regulates VWF release from endothelial cells.
Methods: We studied the effect of RAB5C on vesicle trafficking in human endothelial cells. We performed CRISPR (clustered regularly interspaced short palindromic repeats) interference targeting 2 genetic variants linked to altered VWF levels and evaluated RAB5C expression by reverse transcription-quantitative polymerase chain reaction. We silenced RAB5C or overexpressed RAB5C wild-type, …
A196: Prediction Of Cardiovascular Function Improvement Based On Wearable Device Motion Monitoring And Otnmanba-Bilstm Model, Yixuan Li, Lan Zheng
A196: Prediction Of Cardiovascular Function Improvement Based On Wearable Device Motion Monitoring And Otnmanba-Bilstm Model, Yixuan Li, Lan Zheng
International Journal of Physical Activity and Health
Cardiovascular diseases are among the leading chronic health conditions worldwide, with prolonged physical inactivity or improper exercise increasing the risk of their occurrence. Existing studies suggest that well-structured exercise interventions can significantly enhance cardiac function and improve the adaptability of the cardiovascular system. However, accurately predicting the long-term impact of different exercise durations and intensities on heart health remains challenging due to individual physiological differences, exercise habits, and lifestyle factors. This study employs a data-driven approach to develop a predictive model based on wearable device motion monitoring data, aiming to elucidate the dynamic relationship between exercise and cardiovascular health and …
A197: Perceptual Behavior And Social Interaction Of Chinese College Students Toward Esports, Xianhua Luo
A197: Perceptual Behavior And Social Interaction Of Chinese College Students Toward Esports, Xianhua Luo
International Journal of Physical Activity and Health
Social exchange theory (SET) has been extensively used to recognize students’ perceptual behavior (PB) and social interaction (SI). Research has examined the potential factors of recognition and socialization against the economic factors in individual evaluation, seeking rewards or avoiding costs in relationships. The positive impact of PB and SI is a significant experimental approach to studying social psychology. Therefore, the processes of individuals’ perceptual behavior and their social interactions in Esports might address this research gap. Hence, the purposes of this study were to explain the PBs and SIs toward Esports among college students in China. Method: 341college students were …
A214: Effects Of Tai Chi And Brisk Walking On Sensation In Pn Elders, Qiongqiu Zhao, Qipeng Song
A214: Effects Of Tai Chi And Brisk Walking On Sensation In Pn Elders, Qiongqiu Zhao, Qipeng Song
International Journal of Physical Activity and Health
Peripheral neuropathy (PN) is a prevalent neurological disorder, affecting 26–39.2% of adults aged 65 and older due to peripheral nerve degeneration and associated conditions like diabetes. PN leads to sensory impairments, including diminished tactile sensation, increased fall risk, and mobility issues. Tai Chi (TC) is a low-impact exercise shown to enhance sensory function and balance in healthy older adults, but its effects on PN patients remain unclear. Brisk walking (BW) is a widely recommended exercise for older adults, yet its impact on sensory function in PN is not well-established. This study compares TC and BW interventions on tactile sensation in …
A088: Best Core Stability Training Program For Lower Limb Dysfunction In Stroke Patients: A Network Meta-Analysis, Kaiqi Zheng, Dan Wang, Guoliang Liang, Chunyun Deng
A088: Best Core Stability Training Program For Lower Limb Dysfunction In Stroke Patients: A Network Meta-Analysis, Kaiqi Zheng, Dan Wang, Guoliang Liang, Chunyun Deng
International Journal of Physical Activity and Health
Stroke is the third leading cause of disability and the second leading cause of death among adults. Lower limb dysfunction caused by stroke significantly impairs patients' quality of life. Numerous studies have demonstrated that core stability training (CST) can effectively improve lower limb function in stroke patients, and combining CST with other rehabilitation approaches may yield better therapeutic outcomes. This study aims to identify the most effective CST-based combined intervention for treating lower limb dysfunction in stroke patients. Method: Randomized controlled trials (RCTs) published up to July 22, 2024, were searched from PubMed, Embase, Cochrane Library, Web of Science, CNKI, …
A090: Development And Efficacy Evaluation Of Virtual Reality (Vr)-Based Personalized Exercise Prescriptions For Perimenopausal Women, Runze Zhu, Zekai Wu
A090: Development And Efficacy Evaluation Of Virtual Reality (Vr)-Based Personalized Exercise Prescriptions For Perimenopausal Women, Runze Zhu, Zekai Wu
International Journal of Physical Activity and Health
Perimenopausal women (aged 45–54) frequently experience climacteric symptoms such as vasomotor disturbances, osteoporosis, and cardiovascular risks due to declining ovarian function and estrogen levels. Approximately 75% of women report varying degrees of discomfort, with 80% exhibiting at least one symptom (e.g., sleep disorders, mood fluctuations). Conventional exercise prescriptions often lack specificity to address individual health disparities and comorbidities (e.g., osteoporosis, metabolic dysfunction). This study aimed to develop a virtual reality (VR)-based personalized exercise prescription system to enhance exercise adherence through immersive experiences and evaluate its efficacy in alleviating perimenopausal physiological and psychological symptoms. A personalized exercise prescription generation system was …
A098: Artificial Intelligence Empowers Exercise And Health For The Elderly: Opportunities, Challenges, And Pathways For Implementation, Yaohong Wang, Ke Wang, Yangguiyi Zhao
A098: Artificial Intelligence Empowers Exercise And Health For The Elderly: Opportunities, Challenges, And Pathways For Implementation, Yaohong Wang, Ke Wang, Yangguiyi Zhao
International Journal of Physical Activity and Health
In the context of accelerated global aging and rapid development of artificial intelligence (AI) technology, AI technology provides a new paradigm for improving sports and health management services in the field of elderly care and quality of life. This study aims to reveal the core value of AI technology, analyze the current practical challenges of AI empowerment, and build multidimensional pathways for implementation to promote the coordinated development of healthy aging and technological innovation. Through literature analysis, case studies, and expert interviews, this study systematically explores the application of AI technology in the field of exercise and health of the …
A096: Artificial Intelligence Empowering Physical Education In Higher Education: Logical Tensions And Practical Pathways, Yangguiyi Zhao, Ke Wang, Yaohong Wang
A096: Artificial Intelligence Empowering Physical Education In Higher Education: Logical Tensions And Practical Pathways, Yangguiyi Zhao, Ke Wang, Yaohong Wang
International Journal of Physical Activity and Health
Driven by the strategies of “education digitalization” and “integration of sports and education”, artificial intelligence (AI) technology is reshaping the core values and practical pathways of physical education in higher education. As AI empowers the construction of university sports systems, it has become a key driving force in addressing the challenges of traditional physical education and responding to educational needs. However, AI-driven educational innovation is not a linear evolution; the interplay of its internal logical tensions and external practical constraints necessitates systematic research and pathway exploration. Method: This study systematically explores the multidimensional tensions and coordinated development pathways of artificial …
A095: Blocking Factors And Precision Strategies Of Digital-Driven Governance: Modernization Of Elderly Sports Public Services, Fangfang Yang
A095: Blocking Factors And Precision Strategies Of Digital-Driven Governance: Modernization Of Elderly Sports Public Services, Fangfang Yang
International Journal of Physical Activity and Health
The application of digital technology in the field of sports public services for the elderly presents numerous problems and difficulties. This paper attempts to explore precision strategies for the governance modernization of sports public services for the elderly, driven by digital technology. Analyzing the blocking factors of governance capacity modernization of sports public services driven by digital technologypractical significance for achieving universal health and the construction of a Healthy China. Literature review, expert interviews, and logical analysis. 1. Blocking Factors of Digital-Driven Governance Modernization of Sports Public Services for the Elderly: 1) Weak awareness of digital governance in elderly sports …
A099: Sports-Medicine Integration Treatment Behaviors In Obese College Students: Current Status, Effectiveness, And Influencing Factors, Yunan Li, Dongyue Wei, Shanping Chen, Zhiwei Hu
A099: Sports-Medicine Integration Treatment Behaviors In Obese College Students: Current Status, Effectiveness, And Influencing Factors, Yunan Li, Dongyue Wei, Shanping Chen, Zhiwei Hu
International Journal of Physical Activity and Health
Obesity among college students has become a critical public health issue, impacting their physical and mental health. Sports-Medicine Integration (SMI), an innovative intervention, shows promise for obesity treatment. This study explores the characteristics, effects, and influencing factors of SMI treatments among students, offering insights to improve health literacy and promote holistic well-being in universities. Method: This study employed the "SMI Cognitive Situation Scale" (Gao Shangshang, 2020), the "Exercise Motivation Scale" (Chen Shanping, 2013), and a self-designed "Obesity Treatment Behavior Scale" to survey 1,225 non-physical education majors from general higher education institutions. Data were analyzed using SPSS 29.0. Descriptive statistics assessed …
A109: Analysis Of Optimization Pathways For The Structure Of Sports Consumption In The Digital Economy, Xinran Cui
A109: Analysis Of Optimization Pathways For The Structure Of Sports Consumption In The Digital Economy, Xinran Cui
International Journal of Physical Activity and Health
With the rapid development of the digital economy, the structure of sports consumption is undergoing profound transformations. Traditional sports consumption models can no longer meet the increasingly diversified and personalized demands of consumers. The integration of digital technologies presents new opportunities for the transformation of the sports industry. This study aims to explore how digital technologies can optimize the structure of sports consumption, enhance consumer experiences, and promote the sustainable development of the sports industry. Based on survey data from 524 Chinese residents (282 females and 242 males), this study employs statistical analysis using SPSS to conduct an in-depth examination …
A108: Multidimensional Examination Of The Construction Of The "Educational Joint Community" In School Pe In China, Yefei Fan, Liang Wang
A108: Multidimensional Examination Of The Construction Of The "Educational Joint Community" In School Pe In China, Yefei Fan, Liang Wang
International Journal of Physical Activity and Health
The "educational joint community" (EJC) is a working mode that aims at the healthy and happy growth of primary and secondary school students. Taking schools as the core, regions as the main body, and resources as the link, it promotes effective collaboration among families, schools, and society. The construction of the EJC in school PE in China represents an inevitable choice for achieving high-quality development. It is also an inexorable trend in the pursuit of the national strategies of building a strong sports nation and an education nation. This development is not only in line with the current educational reform …
A104: Explainable Ai-Driven Multimodal Biomechanics Analysis Of Cheerleading Rotational Skills: A Framework For Real-Time Performance Optimization, Jingyi Chen
International Journal of Physical Activity and Health
Current cheerleading skill assessment predominantly relies on coaches' subjective evaluations, lacking quantifiable biomechanical benchmarks. Although electromyography and ground reaction forces provide critical neuromuscular and kinetic insights, their computational integration for automated motion quality assessment remains underdeveloped in aesthetic sports. This study systematically investigates the Tour à la Seconde through explainable machine learning, establishing an interpretable human-AI collaboration framework to bridge empirical coaching knowledge with data-driven biomechanical diagnostics. Twenty-eight elite athletes (18-22 years, 3+ years training) performed standardized Tour à la Seconde while synchronized 14-lead EMG (2000Hz) and triaxial force plate data were captured. Biomechanical feature engineering encompassed: Neuromuscular dynamics: RMS …
A117: Using Bertopic Modeling To Explore Physical Education Utilizing Ict, Qian Sun, Hanjoo Lee, Shutong Liu, Youngbin Cho, Jungmin Kim
A117: Using Bertopic Modeling To Explore Physical Education Utilizing Ict, Qian Sun, Hanjoo Lee, Shutong Liu, Youngbin Cho, Jungmin Kim
International Journal of Physical Activity and Health
Physical education (PE) plays a vital role in student well-being, but China’s traditional PE faces rigid curricula, simplistic assessments, and uneven urban-rural teaching quality. Since the 2017 Next Generation Artificial Intelligence Development Plan, China has promoted ICT integration into PE. Technologies like big data, AI, and VR offer personalized teaching and data-driven practices, aligning with China’s push for innovation-driven development. However, the impact of ICT-integrated PE on physical activity and learning outcomes remains unclear. This study uses BERTopic to analyze research trends and key themes, offering insights for future research and policy. Method: A literature review was conducted using the …