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Articles 16141 - 16170 of 17836
Full-Text Articles in Entire DC Network
Determinants Of Long-Term Care Service Utilization By Mexican-American Family Caregivers, Angelica P. Herrera
Determinants Of Long-Term Care Service Utilization By Mexican-American Family Caregivers, Angelica P. Herrera
Loma Linda University Electronic Theses, Dissertations & Projects
Objectives: Participation in long-term care services may prevent the deterioration of family caregivers' mental and physical health, yet research suggests that Latino caregivers may forego using long-term care services in the absence of other barriers to long-term care use (e.g., lack of insurance).
Methods: An adapted version of the Andersen Model of Health Care Service Utilization served as a framework for examining familism, acculturation, gender roles, religiosity, and knowledge and perceptions about long-term care, as potential determinants of long-term care service use, alongside other factors known for their association with long-term care use (e.g. functional status of care recipient, caregiver …
The Clinical Research Forum And Association Of American Physicians Disagree With Criticism Of The Nih Roadmap, William Crowley Jr, John Courtney, Larry Jameson, Herbert Pardes, Jay Moskowitz, Eugene Orringer, Arthur Rubenstein, Alastair Wood, Richard Rettig, Dennis Ausiello, David Brenner, Francis Collins, Jack Elias, Warner Greene, Ralph Horowitz, Larry Jameson, Elliott Kieff, Craig Thompson, Judith Swain
The Clinical Research Forum And Association Of American Physicians Disagree With Criticism Of The Nih Roadmap, William Crowley Jr, John Courtney, Larry Jameson, Herbert Pardes, Jay Moskowitz, Eugene Orringer, Arthur Rubenstein, Alastair Wood, Richard Rettig, Dennis Ausiello, David Brenner, Francis Collins, Jack Elias, Warner Greene, Ralph Horowitz, Larry Jameson, Elliott Kieff, Craig Thompson, Judith Swain
Faculty Publications
No abstract provided.
Obesity, Physical Activity, And Mortality In A Prospective Chinese Elderly Cohort, Mary Schooling, Tai Hing Lam, Zhi Bin Li, Sai Yin Ho, Wai Man Chan, Kin Sang Ho, May Ked Tham, Benjamin J. Cowling, Gabriel M. Leung
Obesity, Physical Activity, And Mortality In A Prospective Chinese Elderly Cohort, Mary Schooling, Tai Hing Lam, Zhi Bin Li, Sai Yin Ho, Wai Man Chan, Kin Sang Ho, May Ked Tham, Benjamin J. Cowling, Gabriel M. Leung
Publications and Research
Background
In older people, it is unclear whether obesity relates to mortality, which calls into question its etiologic role in disease and its public health relevance. This apparent lack of relationship in older people could be an artifactual result of their diverse health states.
Methods
We used Cox regression analysis to determine whether the effect of body mass index (BMI) (calculated as weight in kilograms divided by the square of height in meters) or physical activity on mortality varied with health status in a prospective cohort study of Chinese people 65 years or older enrolled from 1998 to 2000 at …
Predictors Of Influenza Immunization Among Home Care Clients In Ontario, John P. Hirdes, Dawn M. Dalby, R. Knight Steel, G. Iain Carpenter, Roberto Bernabei, John N. Morris, Brant E. Fries
Predictors Of Influenza Immunization Among Home Care Clients In Ontario, John P. Hirdes, Dawn M. Dalby, R. Knight Steel, G. Iain Carpenter, Roberto Bernabei, John N. Morris, Brant E. Fries
Kinesiology and Physical Education Faculty Publications
Background: This study examined factors associated with the receipt of influenza vaccination among Ontario home care clients.
Methods: Home care clients were assessed, as part of a routine home visit, during a pilot study of the Resident Assessment Instrument – Home Care (RAI-HC) in 12 Ontario Community Care Access Centres (CCACs). The RAI-HC is a multidimensional assessment that identifies clients’ needs and level of functional ability. Multiple logistic regression was used to identify factors associated with influenza immunization in the two years prior to assessment.
Results: The overall rate of immunization reached about 80% by 2002. Factors …
Clark County Child Death Review: 2006 Annual Report, Nevada Institute For Children’S Research And Policy
Clark County Child Death Review: 2006 Annual Report, Nevada Institute For Children’S Research And Policy
Nevada Institute for Children's Research and Policy Reports
The primary goal of all Child Death Review Teams is to prevent future child deaths. The child death review process enables jurisdictions to come together in a collaborative, multidisciplinary forum to openly discuss detailed circumstances in an effort to gain a better understanding of child deaths. The team provides a venue for representatives from a variety of both public and private agencies as well as community organizations to share information in a confidential and non-threatening environment. The National Center for Child Death Review (hereinafter, National Center), which is supported by the Maternal and Child Health Bureau of the U.S. Department …
The Electronic Health Record In Practice: Why, How, And What Next?, Lisa Sprague, Sally Coberly
The Electronic Health Record In Practice: Why, How, And What Next?, Lisa Sprague, Sally Coberly
National Health Policy Forum
This local site visit was intended to allow participants to observe the electronic health record (EHR) as used in practice by two U.S. leaders in technology and quality, the Veterans Health Administration (VHA) and Kaiser Permanente (KP). The VHA has employed an EHR system since 1997; KP is in the process of implementing a standard system for all clinicians nationwide. The site visit was designed to provide an opportunity for participants to explore both the expected benefits from EHR adoption and the specific lessons these two large, integrated delivery systems have learned in their transition from paper to electronic records. …
Criterion Validity Of The Pittsburgh Sleep Quality Index: Investigation In A Non-Clinical Sample, Michael A. Grandner, Daniel F. Kripke, In-Young Yoon, Shawn D. Youngstedt
Criterion Validity Of The Pittsburgh Sleep Quality Index: Investigation In A Non-Clinical Sample, Michael A. Grandner, Daniel F. Kripke, In-Young Yoon, Shawn D. Youngstedt
Faculty Publications
The objective of this study was to investigate the reliability and validity of the Pittsburgh Sleep Quality Index (PSQI) in a non-clinical sample consisting of younger and older adults. There has been little research validating the PSQI with respect to multinight recording as with actigraphy, and more validation is needed in samples not specifically selected for clinical disturbance. Also, the degree to which the PSQI scores may reflect depressive symptoms versus actual sleep disturbance remains unclear. One-hundred and twelve volunteers (53 younger and 59 older) were screened for their ability to perform treadmill exercises; inclusion was not based on sleep …
Low Birth Weight, Very Low Birth Weight And Infant Mortality In San Bernardino County : A Secondary Analysis Of Maternal Factors, Rebecca D. Nanyonjo
Low Birth Weight, Very Low Birth Weight And Infant Mortality In San Bernardino County : A Secondary Analysis Of Maternal Factors, Rebecca D. Nanyonjo
Loma Linda University Electronic Theses, Dissertations & Projects
Purpose: National and state infant mortality rates have slowly declined over the last several years. Despite this reduction, San Bernardino County still has one of the highest infant mortality rates in California and racial disparities between Black and White infants not only persist but continue to widen. These disparities remain at the forefront of concern. Healthy People 2010 target objectives have yet to be reached, while national and state proposed plans have supported the statement that a community's largest health problem is initiated by its infant mortality. The purpose of this study was to investigate maternal factors through use of …
The Relationship Between High Sensitivity C-Reactive Protein, Metabolic Syndrome And Exercise, Micheline A. Vargas
The Relationship Between High Sensitivity C-Reactive Protein, Metabolic Syndrome And Exercise, Micheline A. Vargas
Loma Linda University Electronic Theses, Dissertations & Projects
Background: It is well known that regular physical activity is associated with lower risk of chronic diseases such as diabetes and cardiovascular disease. Physical activity is also considered an important determinant of metabolic syndrome. All levels of metabolic syndrome, diabetes, and cardiovascular disease are thought to involve inflammation. Physical activity may reduce risk, at least in part, by modifying the inflammatory process. Recent studies have demonstrated an inverse relationship between inflammatory markers, such as high sensitivity C-reactive protein (hs-CRP), and physical activity. Elevated hs-CRP appears to be an independent predictor of both CVD and diabetes. Recent evidence also suggests that …
Factors That Influence The Blood Flow Response Of Skin To Electrical Stimulation, Abdul-Majeed Raja Al-Malty
Factors That Influence The Blood Flow Response Of Skin To Electrical Stimulation, Abdul-Majeed Raja Al-Malty
Loma Linda University Electronic Theses, Dissertations & Projects
Female reproductive hormones, aging, global heating and local heating are factors affecting skin blood flow (SBF), but their effect on electrical stimulation (ES) has never been examined until the present investigation. To investigate female reproductive hormones, nine women (age= 25.6±3.5 years) with a normal menstrual cycle (MC) underwent ES in thermoneutral (25°±0.5°C) and warm environments (35°±0.5°C). To investigate aging, ES was applied on active young (n=15, age=32.1±8.3 years) and old (n=8, 64.5±6.2 years) groups in thermoneutral and warm environments. To investigate the effect of global and local heating, groups of 15 and 18 subjects (age= 18-40 years) experienced ES under …
Using The Outcome Questionnaire 45.2 In Obesity Treatment, Adam L. Arechiga
Using The Outcome Questionnaire 45.2 In Obesity Treatment, Adam L. Arechiga
Loma Linda University Electronic Theses, Dissertations & Projects
Purpose: The purpose of this study was to determine if the Outcome Questionnaire 45.2 (OQ-45) can be used in the treatment of obesity to predict participant dropout and initial treatment success, in terms of weight loss (Lambert et. al, 2002a). The OQ-45 has been used with success to predict dropout from psychotherapy in clinical populations. It was hypothesized that higher pretreatment OQ-45 scores would be associated with less program completion and less weight loss by the end of treatment.
Method: The study employed a non-experimental time series design. Seventy-eight participants were recruited from the three local obesity treatment programs, which …
Commencement Program 2006, Loma Linda University
Commencement Program 2006, Loma Linda University
Commencement Programs
CONTENTS
2 | 2006 Events of Commencement
3 | The Academic Procession
4 | Significance of Academic Regalia
5 | The Good Samaritan
6 | The Speakers
15 | The University Honorees
23 | The School Honorees
37 | The Program
- School of Medicine, 38
- School of Pharmacy, 47
- School of Dentistry, 52
- School of Science and Technology and Faculty of Religion, 63
- School of Nursing, 74
- School of Allied Health Professions - Physical Therapy, 80
- School of Allied Health Professions, 86
- School of Public Health, 95
Association Of Physical Activity With Hormone Receptor Status: The Shanghai Breast Cancer Study, Swann Arp Adams, Charles E. Matthews, James R. Hébert, Charity G. Moore, Joan E. Cunningham, Xiou-Oi Shu, Jeanette Fulton, Yutang Gao, Wei Zheng
Association Of Physical Activity With Hormone Receptor Status: The Shanghai Breast Cancer Study, Swann Arp Adams, Charles E. Matthews, James R. Hébert, Charity G. Moore, Joan E. Cunningham, Xiou-Oi Shu, Jeanette Fulton, Yutang Gao, Wei Zheng
Faculty Publications
Evidence exists that breast tumors differing by estrogen receptor (ER) and progesterone receptor (PR) status may be phenotypically distinct diseases resulting from dissimilar etiologic processes. Few studies have attempted to examine the association of physical activity with breast cancer subtype. Such research may prove instructive into the biological mechanisms of activity. Consequently, this investigation was designed to assess the relationship between physical activity and hormone receptor-defined breast cancers in a population of Asian women in which the distribution of receptor types differed from traditional Western populations. Participants, ages 25 to 64 years, were recruited into this population-based, case-control study of …
Patterns Of Smoking Behavior Among Physicians In Yerevan, Armenia, Ray M. Merrill, Gordan B. Lindsay, Paul C. Perrin
Patterns Of Smoking Behavior Among Physicians In Yerevan, Armenia, Ray M. Merrill, Gordan B. Lindsay, Paul C. Perrin
Faculty Publications
Physicians can play an important role in smoking prevention and control. This study will identify smoking prevalence among physicians in Yerevan, Armenia. It will also explore how the smoking behaviors of physicians, their perceived ability to influence patient smoking behavior, and their knowledge about health outcomes related to smoking influence their interaction with patients. Methods: A cross-sectional, self-administered, anonymous survey was conducted in July, 2004, among 12 healthcare facilities in Yerevan. Analyses are based on responses from 240 physicians, representing a 70% response rate. Results: The percentage of current smokers was significantly higher in men than women (48.5% vs. 12.8% …
Aha/Acc Guidelines For Secondary Prevention For Patients With Coronary And Other Atherosclerotic Vascular Disease: 2006 Update, Sidney C. Smith Jr., Jerilyn Allen, Steven N. Blair, Robert O. Bonow, Lawrence M. Brass, Gregg C. Fonarow, Scott M. Grundy, Loren Hiratzka, Daniel Jones, Harlan M. Krumholz, Lori Mosca, Richard C. Pasternak, Thomas A. Pearson, Marc A. Pfeffer, Kathryn A. Taubert
Aha/Acc Guidelines For Secondary Prevention For Patients With Coronary And Other Atherosclerotic Vascular Disease: 2006 Update, Sidney C. Smith Jr., Jerilyn Allen, Steven N. Blair, Robert O. Bonow, Lawrence M. Brass, Gregg C. Fonarow, Scott M. Grundy, Loren Hiratzka, Daniel Jones, Harlan M. Krumholz, Lori Mosca, Richard C. Pasternak, Thomas A. Pearson, Marc A. Pfeffer, Kathryn A. Taubert
Faculty Publications
No abstract provided.
Knowledge, Attitude And Misconceptions Regarding Tuberculosis In Pakistani Patients, Javaid Ahmed Khan, Muhammad Irfan, Amna Zaki, Madiha Beg, Syed Fayyaz Hussain, Nadeem Rizvi
Knowledge, Attitude And Misconceptions Regarding Tuberculosis In Pakistani Patients, Javaid Ahmed Khan, Muhammad Irfan, Amna Zaki, Madiha Beg, Syed Fayyaz Hussain, Nadeem Rizvi
Section of Pulmonary & Critical Care
Objective:
To assess knowledge of patients with tuberculosis; about their disease and misconceptions regarding TB.
Methods:
A cross sectional study was conducted at Out-patient clinics of two teaching hospitals (private and public) in Karachi, Pakistan. A questionnaire was filled for the purpose.
Results:
A total of 170 patients were interviewed, 112 from private and 58 from a public sector hospital. Cough, fever, bloody sputum and chest pain were recognized as the common symptoms of TB. Eleven (7%) patients thought TB was not an infectious disease and 18 (10.6%) did not consider it a preventable disease. Contaminated food was considered the …
Passenger Dies When Semi-Truck Trailer Hits Cow In Roadway, Kentucky Injury Prevention And Research Center
Passenger Dies When Semi-Truck Trailer Hits Cow In Roadway, Kentucky Injury Prevention And Research Center
Fatality Case Reports--Motor Vehicle
On November 8, 2005, a 26-year-old male laborer who was a passenger in a semi-truck died when the driver swerved to avoid hitting a cow that was standing in the parkway lane. The two employees had been traveling westbound for approximately one hour when the driver noticed a cow in his lane. He swerved to avoid hitting the cow but hit it anyway. The tractor and two trailers jack-knifed, traveled through the median with the cab and trailers flipped onto their right sides, slid across the eastbound lanes, then the cab slammed through the guardrail. The cab came to rest …
Assessment Of Whole Grain Intake And Health Correlates In An Aging Population, Alexis Howard
Assessment Of Whole Grain Intake And Health Correlates In An Aging Population, Alexis Howard
Senior Honors Projects
Research suggests that whole grain intake may decrease the risk of heart disease, type II diabetes, hypertension, obesity, and many types of cancer. The overall goal of this work is to increase the health status of an older adult population through comprehensive nutrition risk assessment and exposure to tailored nutrition education interventions. This project involved assisting in baseline and post-intervention assessment of the knowledge, attitude, and intake of whole grain foods within a convenience sample of fifty-eight older adults residing in low-income housing sites across Rhode Island. Anthropometry, including height, weight, waist circumference, and blood pressure was measured, along with …
La Story: Improving Care Management For The Chronically Ill And Chronically Underserved, Eileen Salinsky, Jessamyn Taylor
La Story: Improving Care Management For The Chronically Ill And Chronically Underserved, Eileen Salinsky, Jessamyn Taylor
National Health Policy Forum
This Los Angeles-based site visit examined safety net and private sector efforts to improve care coordination for underserved and vulnerable populations, including the homeless, the uninsured, the undocumented, and individuals with chronic conditions like diabetes, asthma, and severe mental illness. The visit highlighted challenges and innovations in the use of disease management programs, information systems, performance incentives, and managed care as tools for improving care coordination.
Cultural/Interpersonal Values And Smoking In An Ethnically Diverse Sample Of Southern California Adolescents, C. Anderson Johnson, Paula Palmer, Jennifer B. Unger, Sohaila Shakib, Peggy Gallaher, Anamara Ritt-Olson, Michele Mouttapa
Cultural/Interpersonal Values And Smoking In An Ethnically Diverse Sample Of Southern California Adolescents, C. Anderson Johnson, Paula Palmer, Jennifer B. Unger, Sohaila Shakib, Peggy Gallaher, Anamara Ritt-Olson, Michele Mouttapa
CGU Faculty Publications and Research
In ethnically diverse school contexts, values from multiple cultures might influence adolescents' attitudes and behaviors. This study developed scales to assess cultural values among Southern California 6- grade adolescents (N=2281) and evaluated the associations between values and smoking. The scales assessed values salient in many Hispanic and Asian cultures: Respect for Adults (e.g., filial piety, respeto). Interpersonal Harmony (e.g., saving face, simpatia), and Differentiated Gender Roles (e.g., machismo). In cross-sectional and one-year longitudinal models. Respect for Adults and Interpersonal Harmony were associated with a lower risk of lifetime smoking. The associations were significant even after controlling for demographic characteristics, friends' …
Working With The Tabu: Hiv/Aids Education Strategies In Fiji, Amanda Butts
Working With The Tabu: Hiv/Aids Education Strategies In Fiji, Amanda Butts
Independent Study Project (ISP) Collection
The focus of this paper is the cultural tabu, or taboo, in Fiji that prevents the open discussion of sex and therefore complicates education efforts towards HIV/AIDS awareness and prevention. Specific factors perpetuate the tabu including using it as an excuse to simply ignore a complex issue such as HIV/AIDS and using it to keep sex off social agendas in a predominantly Christian nation. Where organizations have taken strides to work with or break the tabu, the author examines and analyzes various education strategies employed by a variety of sectors including schools, health care facilities, faith-based organizations, the HIV positive …
How To Bridge The Gap: An Analysis Of The Coverage And Efficacy Of Volunteer Counseling And Testing Centers In Suba District, Kenya, Joseph Lippi
Independent Study Project (ISP) Collection
The Suba District of western Kenya is one of the areas most affected by the HIV/AIDS epidemic. According to Kenyan Ministry of Health publications, at the end of 2005, Suba District had an HIV/AIDS prevalence of 30%. This paper focuses on the numerous volunteer counseling and testing centers (VCTs) in Suba District that test and educate members of the community in effort to curb the spread of HIV/AIDS. Great efforts have been made to attack the problem of HIV/AIDS in Suba district. This paper seeks to illuminate the numerous factors that keep people in the community from seeking VCT center …
Loaning Health: The Effectiveness Of Microfinance As An Hiv/Aids Intervention Method In Kibera Slums, Lara Berlin
Loaning Health: The Effectiveness Of Microfinance As An Hiv/Aids Intervention Method In Kibera Slums, Lara Berlin
Independent Study Project (ISP) Collection
Three of the major societal issues facing Kenya are poverty, gender inequalities, and HIV/AIDS, each of which acts as a catalyst for the others. In the last twenty years, microfinance has been used as an intervention method combating poverty and women’s disempowerment. As such, this study examines the effectiveness of using microfinance as an HIV/AIDS intervention method in the Kibera slums of Nairobi, Kenya. The research is primarily based upon interviews with Kibera residents and members of microfinance organizations. The findings indicate that most Kibera residents believe microfinance is the best method of reducing the spread of AIDS, especially when …
The Human Ecology Of A Disease: Dissemination Of Resources And Information On Hiv And Aids In Can Tho City And An Giang Province, Lucas Thornblade
The Human Ecology Of A Disease: Dissemination Of Resources And Information On Hiv And Aids In Can Tho City And An Giang Province, Lucas Thornblade
Independent Study Project (ISP) Collection
HIV has spread worldwide. This virus, resulting in as-of-yet incurable destruction of the human immune system, has caused the death of millions in the last two decades through opportunistic infections manifest as AIDS. Though development of prevention and treatment measures have greatly improved in recent years, because of lack of resources, incidence of infection continues to increase annually in nearly all parts of the world including southeast Asia. This paper looks at how the disease has affected people’s lives in Can Tho City and An Giang Province in Vietnam’s southern Mekong Delta. This paper offers an epidemiological and biological argument …
Sex-Education And Preventative And Contraceptive Services: Educação-Sexual E Serviços Contraceptivos E Preventativos, Elizabeth M. Ortiz
Sex-Education And Preventative And Contraceptive Services: Educação-Sexual E Serviços Contraceptivos E Preventativos, Elizabeth M. Ortiz
Independent Study Project (ISP) Collection
Maternal morbidity is one of the leading causes of death amongst women in Latina America. Lack of access to Reproductive Health services has incited a continental epidemic amongst adolescent women - and should be considered a public health crisis. Yet, there is little being done by the governing male bodies to secure access and the Right to Reproductive Health services. This is not only a means of re-enforcing gendered inequalities- but also class, and racial disparities. Reproductive Health in Brazil and Northeastern Brazil in particular, serves as an allegory for socio-economic, gender, ethnic, and racial inequality in the region. The …
Seasonal Variation In Food Intake, Physical Activity, And Body Weight In A Predominantly Overweight Population, Yunsheng Ma, Barbara C. Olendzki, W. Li, Andrea R. Hafner, David E. Chiriboga, James R. Hébert, Mary Jane Campbell, M. Sarnie, Ira S. Ockene
Seasonal Variation In Food Intake, Physical Activity, And Body Weight In A Predominantly Overweight Population, Yunsheng Ma, Barbara C. Olendzki, W. Li, Andrea R. Hafner, David E. Chiriboga, James R. Hébert, Mary Jane Campbell, M. Sarnie, Ira S. Ockene
Faculty Publications
OBJECTIVE:
To describe seasonal variation in food intake, physical activity, and body weight in a predominantly overweight population.
DESIGN:
A longitudinal observational study.
SETTING:
Most of the study participants were recruited from a health maintenance organization (HMO) in central Massachusetts, USA. Additional individuals of Hispanic descent were recruited from outside of the HMO population to increase the ethnic diversity of this sample.
SUBJECTS:
Data from 593 participants, aged 20-70, were used for this investigation. Each participant was followed quarterly (five sampling points: baseline and four consecutive quarters) for 1-year period. Body weight measurements and three 24-h dietary and physical activity …
Association Between Tobacco Use And Body Mass Index In Urban Indian Population: Implications For Public Health In India, Mangesh S. Pednekar, Prakash C. Gupta, Heema C. Shukla, James R. Hébert
Association Between Tobacco Use And Body Mass Index In Urban Indian Population: Implications For Public Health In India, Mangesh S. Pednekar, Prakash C. Gupta, Heema C. Shukla, James R. Hébert
Faculty Publications
Background: Body mass index [BMI, weight (kg)/height (m2)], a measure of relative weight, is a good overall indicator of nutritional status and predictor of overall health. As in many developing countries, the high prevalence of very low BMIs in India represents an important public health risk. Tobacco, smoked in the form of cigarettes or bidis (handmade by rolling a dried rectangular piece of temburni leaf with 0.15–0.25 g of tobacco) or chewed, is another important determinant of health. Tobacco use also may exert a strong influence on BMI.
Methods: The relationship between very low BMI (< 18.5 kg/m2) and tobacco use was examined using data from a representative cross-sectional survey of 99,598 adults (40,071 men and 59,527 women) carried out in the city of Mumbai (formerly known as Bombay) in western India. Participants were men and women aged ≥ 35 years who were residents of the main city of Mumbai.
Results: …
Pnes: Neuropsychological Impairments & Psychological Symptomatology, Adriana Macias
Pnes: Neuropsychological Impairments & Psychological Symptomatology, Adriana Macias
Loma Linda University Electronic Theses, Dissertations & Projects
The present study utilized a standardized neuropsychological evaluation and self report measures to compare 52 female patients, 18 years of age and older with a video-electroencephalogram (V-EEG) confirmed diagnosis of psychogenic non-epileptic seizures (PNES) (n1=29) to a group of left temporal lobe epilepsy (L-TLE) demographically matched patients (n2=23). In an attempt to overcome methodological confounds of previously reported studies, participants were chosen based on stringent exclusion criteria, which barred mixed etiologies. The purpose of this study was to investigate possible differences in neuropsychological functioning, mood, and personality characteristics between individuals with PNES and those with L-TLE. …
Identification Of Critical Determinants On Ace2 For Sars-Cov Entry And Development Of A Potent Entry Inhibitor, Dong P. Han, Adam Penn-Nicholson, Michael W. Cho
Identification Of Critical Determinants On Ace2 For Sars-Cov Entry And Development Of A Potent Entry Inhibitor, Dong P. Han, Adam Penn-Nicholson, Michael W. Cho
Faculty Scholarship
Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus, SARS-CoV. Virus entry into cells is mediated through interactions between spike (S) glycoprotein and angiotensin-converting enzyme 2 (ACE2). Alanine scanning mutagenesis analysis was performed to identify determinants on ACE2 critical for SARS-CoV infection. Results indicated that charged amino acids between residues 22 and 57 were important, K26 and D30, in particular. Peptides representing various regions of ACE2 critical for virus infection were chemically synthesized and evaluated for antiviral activity. Two peptides (a.a. 22–44 and 22–57) exhibited a modest antiviral activity with IC(50) of about 50 μM and 6 μM, …
Worker Crushed To Death By Falling Steel Coil, Kentucky Injury Prevention And Research Center
Worker Crushed To Death By Falling Steel Coil, Kentucky Injury Prevention And Research Center
Fatality Case Reports--Other
On April 13, 2005, a 40-year-old male laborer was moving a 5-feet by 9-inch coil of slitted steel, weighing 6600 pounds, when it fell on him. The laborer was in the process of wrapping a chain through the middle of the coil and through a homemade device on the forks of a forklift when the coil tipped over. As the laborer tried to move away from the falling coil, it landed on his left side, breaking his left leg and causing internal injuries. Other workers in the area did not see, but heard the commotion of the falling coil. The …