Digital Commons Network^™

Exploration And Comparison Of Methods For Combining Population- And Family-Based Genetic Association Using The Genetic Analysis Workshop 17 Mini-Exome, David W. Fardo, Anthony R. Druen, Jinze Liu, Lucia Mirea, Claire Infante-Rivard, Patrick Breheny

Biostatistics Faculty Publications

We examine the performance of various methods for combining family- and population-based genetic association data. Several approaches have been proposed for situations in which information is collected from both a subset of unrelated subjects and a subset of family members. Analyzing these samples separately is known to be inefficient, and it is important to determine the scenarios for which differing methods perform well. Others have investigated this question; however, no extensive simulations have been conducted, nor have these methods been applied to mini-exome-style data such as that provided by Genetic Analysis Workshop 17. We quantify the empirical power and false-positive …

Développement D'Un Système De Cartographie D’Intensité Acoustique Et Transfert En Milieu De Travail, Michel Pearson, André L'Espérance, Louis-Alexis Boudreault, Franck Sgard, Hugues Nélisse, Jérôme Boutin

Rapports de recherche scientifique

Le bruit est un contaminant important en milieu industriel et sa présence a des répercussions sur la santé des travailleurs. En addition, il peut faire partie des causes d'accidents de travail lorsqu'il masque des évènements sonores comme des avertissements sonores ou la parole qui pourraient mettre en garde les travailleurs contre des dangers éventuels.

La réduction du bruit à la source a été reconnue comme étant l'approche à privilégier pour réduire le bruit en milieu industriel. Pour être en mesure de réduire le bruit à la source, il est nécessaire en premier lieu d'identifier les sources de bruit prépondérantes et …

Assessing Association For Bivariate Survival Data With Interval Sampling: A Copula Model Approach With Application To Aids Study, Hong Zhu, Mei-Cheng Wang

Johns Hopkins University, Dept. of Biostatistics Working Papers

In disease surveillance systems or registries, bivariate survival data are typically collected under interval sampling. It refers to a situation when entry into a registry is at the time of the first failure event (e.g., HIV infection) within a calendar time interval, the time of the initiating event (e.g., birth) is retrospectively identified for all the cases in the registry, and subsequently the second failure event (e.g., death) is observed during the follow-up. Sampling bias is induced due to the selection process that the data are collected conditioning on the first failure event occurs within a time interval. Consequently, the …

Summary Of National Models, Policies, And Practices Of Service Needs Of Status Offending Youth, Institute For Public Health And Justice, Status Offenders

Policy & Position Papers

No abstract provided.

The Science Of Public Health Delivery: Evidence, Uncertainties & Research Needs, Glen P. Mays

Health Management and Policy Presentations

Policy initiatives to reform the nation's health system increasingly recognize the need to incorporate public health and prevention strategies. The nation's delivery system for public health, however, varies widely across states and communities in its structure, authority, and capabilities. This session examines research from the growing field of public health services and systems research to identify directions for improving public health delivery.

Mountains Of Injustice : Social And Environmental Justice In Appalachia, Michele Morrone, Geoffrey L. Buckley

Ohio University Press Open Access Books

Research in environmental justice reveals that low-income and minority neighborhoods in our nation’s cities are often the preferred sites for landfills, power plants, and polluting factories. Those who live in these sacrifice zones are forced to shoulder the burden of harmful environmental effects so that others can prosper. Mountains of Injustice broadens the discussion from the city to the country by focusing on the legacy of disproportionate environmental health impacts on communities in the Appalachian region, where the costs of cheap energy and cheap goods are actually quite high.

Through compelling stories and interviews with people who are fighting for …

Evaluation Of Cancer From Exposure To Cyanotoxins In Drinking Water At Grand Lake Saint Marys, Timothy Edward Soward

Master of Public Health Program Student Publications

Background: The Celina Water Department treats and supplies surface water contaminated by cyanotoxins from Grand Lake Saint Marys (GLSM) to approximately 12,000 customers in Celina, Ohio. Cyanotoxins are a biochemically and bioactively diverse group of extremely potent natural toxins in water. A common cyanotoxin called microcystin-LR found in GLSM has been associated with acute liver damage and potentially liver and colorectal cancer.

Methods: In this observational study, the city of Celina (Mercer County) Ohio that had a contaminated surface water supply, the cancer incidence was compared with two control cities, St. Marys, and Wapakoneta (Auglaize County) in Ohio, both served …

Is The Polst Model Desirable For Florida?, Sarah Catherine Spillers, Brittany Lamb

Florida Public Health Review

Florida has one ofthe largest and most rapidly growing elderly populations in the nation. Although advances in medicine are allowing physicians to extend the lives of elderly patients, advances must simultaneously be made in the end-of-life care arena to ensure that the comfort and quality of life of elderly patients is maintained. This paper argues that use of a Physician Orders for Life Sustaining Treatment (POLST) form in Florida would be effective in increasing the accuracy oftranslating patients’ end-of-life wishes into treatment orders, in ensuring the consistency of treatment across settings, and in improving health care provider compliance with patient …

Case Study In Optimal Dosing In Duodenal Ulcer, Karl E. Peace

Biostatistics: Faculty Publications

Georgia Southern University faculty member Karl E. Peace authored "Case Study in Optimal Dosing in Duodenal Eulcer" in Peptic Ulcer Disease.

Frequency And Associated Factors For Care Giving Among Elderly Patients Visiting A Teaching Hospital In Karachi, Pakistan., Waris Qidwai Dr, Mohammad Uzair Abdul Rauf, Seema Sakina, Ayesha Hamid, Sidra Ishaque, Tabinda Ashfaq

Department of Family Medicine

Objective: To study frequency and associated factors for care giving among elderly Patients visiting a teaching hospital in Karachi, Pakistan.
Methodology: A cross sectional questionnaire-based study was conducted at the Community Health Centre (CHC), Aga Khan University Hospital (AKUH) Karachi, Pakistan from September to November 2009. All individuals, visiting the CHC and aged 65 years or above were interviewed after taking written informed consent.
Results: A total of 400 elderly completed the interview. Majority were females, 65-69 years age, More than half of the individuals ie: 227 (85%) had received Care Giver experience for assistance and among these 195(72%) had …

Results From The 2010-11 Readiness For Meaningful Use Of Hit And Patient Centered Medical Home Recognition Survey, Merle Cunningham, Anthony Lara, Peter Shin

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

This brief describes the status of health centers with respect to Electronic Health Record (EHR) adoption, readiness to meet the health information technology (HIT) meaningful use (MU) standards, and readiness to achieve Patient-Centered Medical Home (PCMH) recognition.

Prescriptions For Excellence In Health Care Fall 2011 Dowload Full Pdf

Prescriptions for Excellence in Health Care Newsletter Supplement

No abstract provided.

Portrait De L’Exposition Professionnelle Au Plomb Au Québec Et Niveaux De Plombémie De Janvier 2001 À Décembre 2008, Claude Ostiguy, Ricardo Cordeiro, Gilles Bensimon, Marc Baril

Rapports de recherche scientifique

Cette étude vise à fournir de l'information sur l'exposition professionnelle au plomb des travailleurs québécois et couvre une période de huit années, soit de 2001 à 2008. Le plomb dans l'air est une substance régulièrement analysée par les laboratoires de l'IRSST et la plombémie constitue l'analyse toxicologique la plus fréquente. L'étude informe sur le nombre d'établissements impliqués dans des programmes de santé pour lesquels des analyses ont été demandées et touchant le plomb, dans quelle Classification des Activités Économiques du Québec (CAEQ) et quels secteurs d'activité économique (SAE) ils oeuvrent ainsi que leur localisation géographique par région administrative. Pour de …

Résultats Des Analyses De Substances Chimiques Produites À L’Irsst Pour La Période 2001-2008, Claude Ostiguy, Simon Morin, Gilles Bensimon, Marc Baril

Rapports de recherche scientifique

Le réseau québécois de prévention comprenant la CSST, les Agences de la Santé et des Services Sociaux, les Centres Locaux de Services Communautaires et leurs points de service de même que les Associations Sectorielles Paritaires regroupent plusieurs centaines de personnes œuvrant en santé au travail. Dans le cadre de leurs mandats, ils interviennent régulièrement dans les entreprises afin d'y prélever des échantillons permettant d'évaluer la qualité de l'air. Ces échantillons sont analysés de façon centralisée dans les laboratoires de l'IRSST.

Les résultats des échantillons prélevés dans l'air pour les années 2001 à 2008 ont déjà fait l'objet d'analyse sur une …

Are Student Nurses Ready For Disasters? An Analysis Of Emergency Preparedness Content In Nursing School Textbooks Used In The Miami Valley, Kimberly Caudill

Master of Public Health Program Student Publications

Results of an analysis of nursing textbooks used in the Miami Valley, indicate that there is minimal emergency preparedness content included. The research was based on the textbooks used in the Introduction to Nursing, Psychiatric Nursing, and Community Health Nursing classes at four local nursing schools: Sinclair Community College, Kettering College of Medical Arts, Cedarville University, and Wright State University. The Community Health Nursing classes have the most prepared content, and include extra content in the form of tables and pictures .The analysis indicates that Wright State University does the best job at preparing student nurses to be ready to …

Marital Status And Mortality Among Middle Age And Elderly Men And Women In Urban Shanghai, Puthiery Va, Wan-Shui Yang, Sarah Nechuta, Wong-Ho Chow, Hui Cai, Gong Yang, Shan Gao, Yu-Tang Gao, Wei Zheng, Xiao-Ou Shu, Yong-Bing Xiang

Peer Reviewed Articles

Background: Previous studies have suggested that marital status is associated with mortality, but few studies have been conducted in China where increasing aging population and divorce rates may have major impact on health and total mortality.

Methods: We examined the association of marital status with mortality using data from the Shanghai Women’s Health Study (1996–2009) and Shanghai Men’s Health Study (2002–2009), two population-based cohort studies of 74,942 women aged 40–70 years and 61,500 men aged 40–74 years at the study enrollment. Deaths were identified by biennial home visits and record linkage with the vital statistics registry. Marital status was categorized …

A Randomized Trial Of A Diet And Exercise Intervention For Overweight And Obese Women From Economically Disadvantaged Neighborhoods: Sisters Taking Action For Real Success (Stars), Sarah Wilcox, Patricia A. Sharpe, Deborah Parra-Medina, Michelle L. Granner, Brent E. Hutto

Faculty Publications

Background - Lower socioeconomic status at both the individual and neighborhood level is associated with increased health risks. Weight loss can reduce this risk, but few high quality weight loss studies target this population.

Objectives - STARS tests a culturally-appropriate, group-based behavioral and social support intervention on body weight and waist circumference in women from financially disadvantaged neighborhoods.

Design - A stratified (by BMI) randomized trial. Randomization to group was generated by a random numbers table with allocation concealment by opaque envelopes.

Methods - Participants 25-50 years who had a BMI ≥ 25 kg/m² and a waist circumference ≥ …

Two Tree Trimmers Die When Struck By Errant Semi Tractor-Trailer, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Motor Vehicle

One spring morning in 2010, three male tree trimmers set up a work site in a highway intersection at the base of a mountain. As one tree trimmer removed equipment from the truck, two other tree trimmers, 21- and 32-years old, posted signage in the intersection. The two tree trimmers were located on the shoulder of the highway. A semi tractor-trailer was driving down the mountain toward the intersection, when its brakes failed. To avoid hitting vehicles in front of the semi, the driver steered to the left, crossed the intersection, striking both tree trimmers with the semi tractor-trailer. Both …

Depicting Estimates Using The Intercept In Meta-Regression Models: The Moving Constant Technique, Blair T. Johnson Dr., Tania B. Huedo-Medina Dr.

CHIP Documents

In any scientific discipline, the ability to portray research patterns graphically often aids greatly in interpreting a phenomenon. In part to depict phenomena, the statistics and capabilities of meta-analytic models have grown increasingly sophisticated. Accordingly, this article details how to move the constant in weighted meta-analysis regression models (viz. “meta-regression”) to illuminate the patterns in such models across a range of complexities. Although it is commonly ignored in practice, the constant (or intercept) in such models can be indispensible when it is not relegated to its usual static role. The moving constant technique makes possible estimates and confidence intervals at …

Beverage Consumption And Bmi Of British Schoolchildren Aged 9-13 Years, Tara Coppinger, Y. M. Jeanes, M. Mitchell, S. Reeves

Publications

Objective Adequate fluid intake has been well documented as important for health but whether it has adverse effects on overall energy and sugar intakes remains under debate. Many dietary studies continue to refrain from reporting on beverage consumption, which the present study aimed to address. Design A cross-sectional survey investigated self-reported measures of dietary intake and anthropometric measurements. Setting Primary and secondary schools in south-west London, UK. Subjects Boys and girls (n 248) aged 9-13 years. Results Boys consumed 10 % and girls consumed 9 % of their daily energy intake from beverages and most children had total sugar intakes …

Pre- And Post-Bronchodilator Lung Function As Predictors Of Mortality In The Lung Health Study, David M. Mannino, Enrique Diaz-Guzman, Sonia Buist

Preventive Medicine and Environmental Health Faculty Publications

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is supposed to be classified on the basis of post-bronchodilator lung function. Most longitudinal studies of COPD, though, do not have post-bronchodilator lung function available. We used pre-and post bronchodilator lung function data from the Lung Health Study to determine whether these measures differ in their ability to predict mortality.

METHODS: We limited our analysis to subjects who were of black or white race, on whom we had complete data, and who participated at either the 1 year or the 5 year follow-up visit. We classified subjects based on their baseline lung function, according …

Knowledge, Perceptions And Myths Regarding Infertility Among Selected Adult Population In Pakistan: A Cross-Sectional Study, Sumera Ali, Raafay Sophie, Ayesha M. Imam, Faisal I. Khan, Syed F. Ali, Annum Shaikh, Syed Farid-Ul-Hasnain

Community Health Sciences

Background: The reported prevalence of infertility in Pakistan is approximately 22% with 4% primary and 18% secondary infertility. Infertility is not only a medical but also a social problem in our society as cultural customs and perceived religious dictums may equate infertility with failure on a personal, interpersonal, or social level. It is imperative that people have adequate knowledge about infertility so couples can seek timely medical care and misconceptions can be rectified.We aim to assess the knowledge, perception and myths regarding infertility and suggest ways to improve it.
Methods: A cross-sectional survey was carried out by interviewing a sample …

Improving The Population’S Health: The Affordable Care Act And The Importance Of Integration, Lorian E. Hardcastle, Katherine L. Record, Peter D. Jacobson, Lawrence O. Gostin

O'Neill Institute Papers

Heath care and public health are typically conceptualized as separate, albeit overlapping, systems. Health care’s goal is the improvement of individual patient outcomes through the provision of medical services. In contrast, public health is devoted to improving health outcomes in the population as a whole through health promotion and disease prevention. Health care services receive the bulk of funding and political support, while public health is chronically starved of resources. In order to reduce morbidity and mortality, policymakers must shift their attention to public health services and to the improved integration of health care and public health. In other words, …

Poor Women With Sexually Transmitted Infections: Providers’ Perspectives On Diagnoses, Genevieve R. Cox

Sociology

This article presents results from a study of health care providers, mainly nurses and nurse practitioners, who routinely diagnose sexually transmitted diseases (STDs) in rural low-income populations in West Virginia (WV). A qualitative analysis of eighteen semi-structured interviews reveals that providers who consistently work with low-income populations believe patients undergo a negative change in self-image in response to a chronic STD diagnosis. Providers express concerns about a number of issues related to low-income, rural women’s access to sexual health care and see the need for more sexuality education, more funding for free and reduced cost clinics, and more available health …

Il Faut Manger: A Study Of Women’S Body Image And Obesity In Mali, Jennifer Denike

Independent Study Project (ISP) Collection

Africa has long been a region of the world marked by the media as one of rail thin children with distended bellies and older men and women with cracked and wrinkled skin sagging off their bones. Media outlets like BBC, CNN, and the New York Times focus entire sections of their websites to special reports entitled ‘Famine in Africa’2, ‘Food Crisis in Niger’3, and ‘East Africa Famine 2011’4. Photos of children curled up on the ground, ribs and bones protruding at every angle grace the pages of nearly every magazine and newspaper. Nongovernmental organizations plead for donations and host fundraisers …

Effectively Filling Gaps In Care: A Comparative Study Of Models Of Government Partnerships With Community Health Organizations In Kwazulu-Natal, South Africa, Madeline Ross

Independent Study Project (ISP) Collection

This study conducted Amatkiulu, Impendle, and Durban, KwaZulu-Natal, South Africa, utilizes three case studies to form a comparative analysisof the effectiveness of different models of public-private partnerships. Two expert interviews, three informal interviews, and many hours of observation inform this analysis of community health worker organizations employed through government clinics, tuberculosis tracer teams hired by government clinics, and independent non-governmental organizations heavily subsidized by the government. Subjective analysis found that the partnership between the Department of Health and a primary healthcare NGO, providing a wide range of comprehensive services, operated with the best efficiency and quality of care.

Understanding Social Marketing In A Not-For-Profit Ngo Setting: An Internship With Pace In Eastern Uganda, Veronica L. Tuerffs

Independent Study Project (ISP) Collection

The organization PACE (Programme for Accessible health, Communication and Education) focuses on generating a positive health impact throughout Uganda by the means of social marketing and other proven, evidence based techniques. An internship with the organization took place over the course of six weeks and was conducted under the A2L (Access to Life) program which is located in four of the country’s eastern districts. The focus of the health and sales communication internship was the implementation of PACE’s marketing scheme on their life-saving products and how the products and organization are perceived.

Any of the information gathered during this time …

When Mountain Bellies Grow Round: Localized Knowledge And Behaviors Facilitating Pregnancy And Childbirth In Phaphlu, Nepal, Cailin Marsden

Independent Study Project (ISP) Collection

In attempts to gain a level of understanding of a community’s localized experiences, beliefs, practices, and roles around pregnancy and childbirth, ethnographic fieldwork was conducted with the mothers and fathers of Phaphlu in the Solukhumbu district of Nepal. Aimed at the validation of diverse and localized ways of knowing revealed during the fieldwork period, this paper applies anthropologist Bridgette Jordan’s theoretical framework of authoritative knowledge to the emergent themes of subjectively understood childbirth (knowledge acquisition and flow, role of the husband, and protective behavior.)

Creating & Optimizing Children & Youth Planning Boards, Institute For Public Health And Justice, Community Participatory Work

Policy & Position Papers

No abstract provided.

Combined Impact Of Lifestyle Factors On Cancer Mortality In Men, Chong-Do Lee, Xuemei Sui, Steven P. Hooker, James R. Hébert, Steven N. Blair

Faculty Publications

PURPOSE - The impact of lifestyle factors on cancer mortality in the U.S. population has not been thoroughly explored. We examined the combined effects of cardiorespiratory fitness, never smoking, and normal waist girth on total cancer mortality in men.

METHODS - We followed a total of 24,731 men ages 20-82 years who participated in the Aerobics Center Longitudinal Study. A low-risk profile was defined as never smoking, moderate or high fitness, and normal waist girth, and they were further categorized as having 0, 1, 2, or 3 combined low-risk factors.

RESULTS - During an average of 14.5 years of follow-up, …