Digital Commons Network^™

Community Quarantines And Social Protection Programs: Philippine Pandemic Response Viewed Through The Human Security Framework, Leslie Advincula-Lopez, Jessica Sandra R. Claudio, Haraya Marikit C. Mendoza

Development Studies Faculty Publications

No abstract provided.

Exploring Latent Clusters In Pediatric Ocd Based On Symptoms, Severity, Age, Gender, And Comorbidity, Orri Smárason, Robert R Selles, Davíð R M A Højgaard, John R Best, Karin Melin, Tord Ivarsson, Per Hove Thomsen, Bernhard Weidle, Nicole Michelle Mcbride, Eric A Storch, Daniel Geller, Sabine Wilhelm, Lara J Farrell, Allison M Waters, Sharna Mathieu, Noam Soreni, S Evelyn Stewart, Gudmundur Skarphedinsson

Center for Medical Ethics and Health Policy Staff Publications

Given diverse symptom expression and high rates of comorbid conditions, the present study explored underlying commonalities among OCD-affected children and adolescents to better conceptualize disorder presentation and associated features. Data from 830 OCD-affected participants presenting to OCD specialty centers was aggregated. Dependent mixture modeling was used to examine latent clusters based on their age- and gender adjusted symptom severity (as measured by the Children's Yale-Brown Obsessive-Compulsive Scale; CY-BOCS), symptom type (as measured by factor scores calculated from the CY-BOCS symptom checklist), and comorbid diagnoses (as assessed via diagnostic interviews). Fit statistics favored a four-cluster model with groups distinguished primarily by …

Ai And Data Science For Public Policy, Kenneth Benoit

Research Collection School of Social Sciences

Artificial intelligence (AI) and data science are reshaping public policy by enabling more data-driven, predictive, and responsive governance, while at the same time producing profound changes in knowledge production and education in the social and policy sciences. These advancements come with ethical and epistemological challenges surrounding issues of bias, transparency, privacy, and accountability. This special issue explores the opportunities and risks of integrating AI into public policy, offering theoretical frameworks and empirical analyses to help policymakers navigate these complexities. The contributions explore how AI can enhance decision-making in areas such as healthcare, justice, and public services, while emphasising the need …

A Dynamic Urban Digital Twin Integrating Longitudinal Thermal Imagery For Microclimate Studies, Vasantha Ramani, Marcel Ignatius, Joie Lim, Filip Biljecki, Clayton Miller

Research Collection College of Integrative Studies

Recently, the concept of a digital twin for the built environment has received significant attention due to its potential benefits to urban planners, engineers, and designers. The development of tools that aid in integrating real-world physical systems with digital capabilities is essential for advancing digital twin technology. In this work, we present one such digital twin tool that integrates the longitudinal thermal envelope data of buildings on the campus of the National University of Singapore with a virtual 3D model. Thermal images of the buildings were captured using a neighborhood-scale infrared observatory for a few months. The temperature profile of …

From Personal Comfort To District Performance: Using Smartwatch And Wifi Data For Occupant-Driven Operation, Martín Mosteiro-Romero, Matias Quintana, Clayton Miller, Rudi Stouffs

Research Collection College of Integrative Studies

This work proposes the use of a data-driven, agent-based model of building occupants’ activities and thermal comfort in an urban university campus in order to assess how district operation strategies can be leveraged to support the transition to flexible work arrangements. The results show that when users are given the flexibility to pursue more comfortable workspaces, they are still comfortable only 58% of the time.

Legal Analysis Of The Laws To Combat Illicit Drug Trafficking At Sain Tonga, Sikini Falesiva

World Maritime University Dissertations

No abstract provided.

Examining Nigeria’S Blue Economy Initiative Through The Establishment Of Nigeria’S New Ministry Of Marine And Blue Economy : Opportunities And Challenges, Ikenna Peter Ndubueze

World Maritime University Dissertations

No abstract provided.

The Role Of The Philippine Coast Guard Toward Sustainable Coastal And Marine Tourism In Relation To United Nations Sustainable Development Goals, Kimmy Carrie Necesario

World Maritime University Dissertations

No abstract provided.

Improving Socioeconomic Conditions For Ghanaian Fishers On Flagged Vessels : Policy Recommendations For The Fishing Industry, Robert Nyarkoh

World Maritime University Dissertations

No abstract provided.

Acci̇Dental Oi̇L Polluti̇On From Tankers İN The Caspi̇An Sea : Problem Causes And Lessons Learned, Emin Sadirov

World Maritime University Dissertations

No abstract provided.

Navigating The Just Transition : Ensuring Safety Of Seafarers In Adoption Of Alternative Fuels In Maritime Sector, Simranjeet Singh

World Maritime University Dissertations

No abstract provided.

Maritime Safety In Tonga : Developing The Island Nation’S Maritime Casualty Investigation, Susitina Ta'ai

World Maritime University Dissertations

No abstract provided.

A Study On The Risk Assessment Of Japanese Domestic Passenger Vessel Accident, Miki Yanagisawa

World Maritime University Dissertations

No abstract provided.

The Feasibility And Challenges Of Implementing A Green Port Policy Framework In Bangladesh, Md. Al Hasnat

World Maritime University Dissertations

No abstract provided.

Assessing The Role Of Ocean Literacy In Fostering Sustainable Practices And Conservation In Kenya : Secondary School Teachers’ Perspectives, Victoria Mere Tuva

World Maritime University Dissertations

No abstract provided.

Solid Waste Management Practices And The Role Of Public Perception In West Point, Monrovia, Liberia, Lucy Garmai Varnie

World Maritime University Dissertations

No abstract provided.

The Impact Of Marine Protected Areas In Coastal Communities In Liberia : A Case Study On The Lake Piso Multiple Sustainable Use Reserve, Doris Wrehyonoh Yahn

World Maritime University Dissertations

No abstract provided.

Use Of Environmental Dna To Examine Seagrass Ecosystem Functionality, Kathy Ann Young

World Maritime University Dissertations

No abstract provided.

Estimating The Social Costs Of Emissions And Pollution From Malawi’S Inland Shipping And Dry Port, Joel Herald Kossam

World Maritime University Dissertations

No abstract provided.

Financial Strategies For State-Owned Shipping Companies : Case Studies On Container, Dry Bulk, And Tanker Shipping Sectors., Faith Nazi Maraga, Olga Do Rosário

World Maritime University Dissertations

No abstract provided.

Update On Pediatric Cancer Surveillance Recommendations For Patients With Neurofibromatosis Type 1, Noonan Syndrome, Cbl Syndrome, Costello Syndrome, And Related Rasopathies, Melissa R Perrino, Anirban Das, Sarah R Scollon, Sarah G Mitchell, Mary-Louise C Greer, Marielle E Yohe, Jordan R Hansford, Jennifer M Kalish, Kris Ann P Schultz, Suzanne P Macfarland, Wendy K Kohlmann, Philip J Lupo, Kara N Maxwell, Stefan M Pfister, Rosanna Weksberg, Orli Michaeli, Marjolijn C J Jongmans, Gail E Tomlinson, Jack Brzezinski, Uri Tabori, Gina M Ney, Karen W Gripp, Andrea M Gross, Brigitte C Widemann, Douglas R Stewart, Emma R Woodward, Christian P Kratz

Center for Medical Ethics and Health Policy Staff Publications

Neurofibromatosis type 1 (NF1), Noonan syndrome, and related syndromes, grouped as RASopathies, result from dysregulation of the RAS-MAPK pathway and demonstrate varied multisystemic clinical phenotypes. Together, RASopathies are among the more prevalent genetic cancer predisposition syndromes and require nuanced clinical management. When compared with the general population, children with RASopathies are at significantly increased risk of benign and malignant neoplasms. In the past decade, clinical trials have shown that targeted therapies can improve outcomes for low-grade and benign neoplastic lesions but have their own challenges, highlighting the multidisciplinary care needed for such individuals, specifically those with NF1. This perspective, which …

Pancreatitis Pain Quality Changes At Year 1 Follow-Up, But Gp130 Remains A Biomarker For Pain, Jami L Saloman, Kristofer Jennings, Kimberly Stello, Shuang Li, Anna Evans Phillips, Kristen Hall, Evan L Fogel, Santhi Swaroop Vege, Dana K Andersen, William E Fisher, Christopher E Forsmark, Phil A Hart, Stephen J Pandol, Walter G Park, Mark D Topazian, Stephen K Van Den Eeden, Jose Serrano, Darwin L Conwell, Liang Li, Dhiraj Yadav

Center for Medical Ethics and Health Policy Staff Publications

Background/objectives: Debilitating abdominal pain is a common symptom affecting patients with chronic pancreatitis (CP). CP pain is dynamic due to multiple underlying mechanisms. The objective of this study was to 1) evaluate changes in pain phenotype at one year follow-up and 2) validate putative pain biomarkers in a prospective cohort study.

Methods: The Neuropathic and Nociceptive PROMIS-PQ questionnaires were used to classify pain for participants with in the PROCEED study. Putative serum biomarkers were measured via immunoassay.

Results: At enrollment, 17.6 % (120/681) subjects with CP reported no pain in the previous year. Of those, 29 % experienced pain during …

First Interim Results From Fine-Real: A Prospective, Non-Interventional, Phase 4 Study Providing Insights Into The Use And Safety Of Finerenone In A Routine Clinical Settingfirst Interim Results From Fine-Real: A Prospective, Non-Interventional, Phase 4 Study Providing Insights Into The Use And Safety Of Finerenone In A Routine Clinical Setting, Susanne B Nicholas, Ricardo Correa-Rotter, Nihar R Desai, Lixin Guo, Sankar D Navaneethan, Kevin M Pantalone, Christoph Wanner, Stefanie Hamacher, Samuel T Fatoba, Andrea Horvat-Broecker, Antonio Garreta-Rufas, Alain Gay, Martin Merz, David C Wheeler

Center for Medical Ethics and Health Policy Staff Publications

Background: Finerenone, a selective non-steroidal mineralocorticoid receptor antagonist, improves kidney and cardiovascular outcomes in patients with chronic kidney disease (CKD) associated with type 2 diabetes (T2D). The FINE-REAL study (NCT05348733) aims to evaluate the characteristics and treatment patterns of participants treated with finerenone in clinical practice.

Methods: FINE-REAL is a prospective, single-arm, non-interventional study of patients initiated on finerenone as part of their routine care in accordance with country-approved labels. The study, initiated in June 2022, is expected to be completed by January 2028. The cutoff for this pre-specified interim analysis was June 13, 2023.

Results: Participants were …

Automated Electronic Health Record Data Extraction And Curation Using Extractehr, Tamara P Miller, Kelly D Getz, Edward Krause, Yun Gun Jo, Sandhya Charapala, M Monica Gramatages, Karen Rabin, Michael E Scheurer, Jennifer J Wilkes, Brian T Fisher, Richard Aplenc

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Although the potential transformative effect of electronic health record (EHR) data on clinical research in adult patient populations has been very extensively discussed, the effect on pediatric oncology research has been limited. Multiple factors contribute to this more limited effect, including the paucity of pediatric cancer cases in commercial EHR-derived cancer data sets and phenotypic case identification challenges in pediatric federated EHR data.

Methods: The ExtractEHR software package was initially developed as a tool to improve clinical trial adverse event reporting but has expanded its use cases to include the development of multisite EHR data sets and the support …

Measuring Perceived Utility Of Genomic Sequencing: Development And Validation Of The Genetic Utility (Gene-U) Scale For Adult Screening, Hadley Stevens Smith, Caryn Kseniya Rubanovich, Jill Oliver Robinson, Ariel N Levchenko, Sarah A Classen, Janet Malek, Adam H Buchanan, Barbara Biesecker, Kyle B Brothers, Benjamin S Wilfond, Christine Rini, Cinnamon S Bloss, Amy L Mcguire, Sara J Knight

Center for Medical Ethics and Health Policy Staff Publications

Purpose: As population-based screening programs to identify genetic conditions in adults using genomic sequencing (GS) are increasingly available, validated patient-centered outcome measures are needed to understand participants' experience. We aimed to develop and validate an instrument to assess the perceived utility of GS in the context of adult screening.

Methods: Informed by a 5-domain conceptual model, we used a 5-step approach to instrument development and validation: (1) item writing, (2) cognitive testing, (3) pilot testing and item reduction, (4) psychometric testing, and (5) evaluation of construct validity. Adults undergoing risk-based or population-based GS who had received GS results as part …

Exploring The Transformative Effect Of Community Managed Nature Tourism On Community Empowerment In Odisha: Perspective From Local Residents, Jagadish Behera, Rajdeep Deb

Journal of Tourism Insights

In this study, an attempt was made to examine the relationships between community managed nature tourism and community empowerment from the local residents’ perspective, as well as to test how these relationships varied among different demographic characteristics of residents. For this study, five hypotheses were proposed based on the review of literature and tested using residents living near the protected nature camps in Odisha. A cross-sectional survey was carried out on 184 local residents selected from across the eight nature camps of Odisha. The variables examined in this study included residents' gender, age, education, occupation, and income. Data analysis was …

The Pressing Necessity For Maternal Healthcare Reform In The Us, Chelsea Cousin

Opinion Matters: Student Analyses of World News

This Op-Ed discusses the impact of the historical legacy of slavery and anti-Black discrimination on inequities in modern Black female maternal health and pre and post natal care.

Veteran Health Equity: Reflecting On Patient Experiences And Unmet Health Needs Among Veterans Of Color, Mariah Brennan, Jeanette Harvie, Deborah Bradbard, Rosalinda V. Maury

Institute for Veterans and Military Families

Research has consistently demonstrated the presence and severity of racial health disparities in the U.S., particularly for Black Americans. Many of the root causes of these disparities are complex and are associated with various forms of structural discrimination. This study examines the health experiences of veterans of color, particularly their interactions in the VA and Military Health system to better understand racial/ethnic disparities across disease burden, mortality, and indicators of patient healthcare experiences. This mixed-methods study included an online survey (n=219) and virtual focus groups and one-on-one interviews (n=17). Overall, a majority of study participants had positive patient experiences from …

Sustainability Strengths, Weaknesses, Opportunities, And Threats And Pestel Analysis For Special District Revenue Generation, Toyasha Sebbag

Walden Dissertations and Doctoral Studies

This study addresses the ability of the client organization to create new programming that is separate from its general fund and is revenue-neutral because the client organization is a conservation district operating under the California Water Code Division 21 Sections 74000-76501. The constraint of California Proposition 13’s property tax rate increases makes it difficult for the client organization to fund new programming. To overcome these limitations, the multiple streams framework (MSF) and the s/SWOT and PESTEL frameworks were used to analyze the role of policy entrepreneurs and address potential limitations in the client organization’s creation of new programming, ensuring sustainability …

Effective Strategies To Mitigate The Impact Of Cargo Shipment Abandonment, Ozoemenam Peter Peter Ohagwu

Walden Dissertations and Doctoral Studies

Business leaders in multiple U.S. exporters refuse to pay freight charges and abandon their cargo shipments, leaving shipping business leaders with monetary losses. Some small and medium-sized U.S.-based shippers lack effective strategies to address the risk of cargo shipment abandonments. Grounded in the theory of constraints, the purpose of this qualitative pragmatic inquiry study was to explore the effective strategies used by small and medium-sized U.S.-based shippers to successfully mitigate the risk of cargo shipment abandonment. The participants included three U.S. shipping industry leaders from non-vessel-operating common carriers and three from vessel-operating common carriers, all with an average of 25 …