Digital Commons Network^™

A Review Of Olanzapine In The Treatment Of Cancer Anorexia-Cachexia Syndrome, Ivy O Poon, Veronica Ajewole, Ursula K Braun

Center for Medical Ethics and Health Policy Staff Publications

Background: Cancer anorexia-cachexia syndrome (CAS) is a multifactorial condition that is highly prevalent in advanced cancer patients and associated with significant reduction in functional performance, reduction in quality of life, and increased mortality. Currently, no medications are approved for this indication. Recently, the American Society of Clinical Oncology (ASCO) released a rapid recommendation suggesting that low-dose olanzapine once daily may be used to treat cancer cachexia. Many questions still exist on how to use olanzapine for this indication in clinical practice. The objective of this review is to identify existing knowledge on the use of olanzapine for CAS.

Methods: A …

Board Of Trustees Minutes, Feb. 16 2024, Indiana State University Board Of Trustees

Board of Trustees

No abstract provided.

Efficient Primary Education Service Delivery In The Local Nigerian Government, Kezia Igwebueze

Walden Dissertations and Doctoral Studies

The inefficient service delivery of local government in Nigeria in the provision and maintenance of primary education and educational facilities is problematic. There is the dearth of instructional, recreational, residential, and social facilities in the learning environment that enable teachers and learners to carry out their work and assimilate efficiently. The purpose of this qualitative case study was to explore the determining factors that influence the culture of inefficiency in the primary education service delivery function across local government councils in Nigeria and investigate how the culture of efficiency can be recreated. Sutherland’s differential association theory provided the theoretical foundation …

Qualitative Study Of Public Policy Affecting Public University Students: How Positive Psychology May Lessen Racism, Russell F. Peck

Walden Dissertations and Doctoral Studies

Racism, racial inequity, and racial violence, including micro-aggressions (slurs and fearful glances) are endemic in modern American society. Finding ways to eliminate or at least mitigate racism and racial violence is important, not only for public safety but also to ensure equality, fairness, and social harmony among every stratum of American society. The purpose of this study was to determine if teaching positive psychology in Boston, Massachusetts (MA)-area university college classrooms helped improve race relations. The primary research question involved determining factors that create racism and racial violence in society. The second research question was about if an education policy …

Exploring The Potential Of E-Government In Reducing Corruption – Case Of Egypt, Mahinour Abou Elseoud

Theses and Dissertations

Many countries have recognized the significance of electronic work transition to application, frequently known as e-government, with the purpose of improving their bureaucratic performance and reducing corruption. From an economic standpoint, transparency may boost government efficiency as it increases the government capacity and, eventually, fosters good governance by reducing corruption and inefficiency. As a result, this study aims to analyze the correlation between e-government and corruption, as well as whether e-government reduced the detrimental effects of corruption on public trust. To accomplish this objective, the thesis focuses on in-depth interviews with citizens of all ages, socioeconomic and educational backgrounds, as …

Out-Of- School Time Use In Pakistan: A Qualitative Study Featuring Youth's Voices, Salima Kerai, Marium Ibrahim, Tonje M. Molyneux, Uzma Hussain, Anne Gadermann, Rosemin Kassam, Almina Pardhan Dr., Eva Oberle

Institute for Educational Development, Karachi

The current study addresses the lack of out-of-school time (OST) research in low- and middle-income countries by exploring OST use in the context of Pakistan and incorporating youth's voices. Using a qualitative descriptive design with focus-group discussions, we conducted a study in three middle schools set in low- to middle-income neighborhoods in urban and rural areas of Karachi, Pakistan. We engaged 86 youth (50% girls; aged 10–15 years) that were purposefully selected from grade six (31.4%), seven (44.2%) and eight (24.4%) classrooms, balancing gender and locality. In each focus group, we asked participants to describe their afterschool activity routine on …

Isn’T There A Better Way To Nominate Presidential Candidates?, Elaine Kamarck

Brookings Scholar Lecture Series

This lecture examines why every four years the major political parties undertake a drawn-out, confusing series of primaries, caucuses, and conventions to determine their presidential nominees. Over the years, a number of rational and more orderly ways to select presidential nominees have been proposed but none of these ideas have been adopted. Brookings Institution scholar Elaine Kamarck, who has written extensively on the topic and served as a presidential and presidential campaign advisor, addresses these topics and more.

"They Are Usually Borderline Homeless": Exploring The Nexus Of Homelessness, Housing Instability, Successful Reentry, And Long-Term Reintegration, Emily Troshynski, Carolyn Willis

Criminal Justice Faculty Research

For previously incarcerated persons, affordable and safe housing options are scarce. Barriers to securing housing include federal mandates (i.e., eligibility requirements) as well as local rules and regulations (i.e., zoning and ordinances). When housing is available, disclosing criminal history on applications impacts individuals’ chances to rent (Philips & Spencer, 2013). A lack of a consistent rental history, no personal and/or employment references, and securing capital to cover security deposits are added challenges. Since parole rules direct ex-convicts not to associate with others that have a criminal record, living with partners, friends, and family members may not be an option. Research …

Clean Investment Monitor: Q4 2022 — Q3 2023, Madison Dwyer, Zachary Billot, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.

Environment

This fact sheet presents investment trends in clean manufacturing, energy and industry, and retail in the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. This fact sheet examines data from the Q3 2023 update of the Clean Investment Monitor (CIM), a joint project of Rhodium Group and the MIT Center for Energy and Environmental Policy Research.

The Employment Situation Of Veterans: January 2024, Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

Veteran employment trends and statistics among various demographics during January 2024.

America’S Black Homelessness Epidemic: Rooted In Systemically Racist Public Policies And Administration, Terry L. Lewis

Walden Dissertations and Doctoral Studies

No abstract provided.

Student Perceptions Of Satisfactory Academic Progress Practices In Higher Education, Christopher Giovanni Rodriguez

Walden Dissertations and Doctoral Studies

No abstract provided.

Women’S Peacebuilding Leadership During The Covid-19 Pandemic, Briana Mawby, Carolyne Komen, John Porten

Kroc IPJ Research and Resources

Women's Peacebuilding Leadership during the COVID-19 Pandemic is the first annual Women Waging Peace report, a new publication that provides a resource for policymakers and funders, created directly from the recommendations and priorities of women peacebuilders around the world. This report leverages the experiences and perspectives of women peace leaders to communicate clear priorities to funders and policymakers about what matters most for building sustainable and long-lasting peace.

This report provides:

• Analysis of the challenges and opportunities that the global community of women peacebuilders experienced in 2023;
• Recommendations for funding and programming priorities for 2024; and
• In-depth findings related to …

The Charge Forward: An Assessment Of Electric Vehicle Charging Infrastructure In New York City, Christopher S. Cali

Dissertations, Theses, and Capstone Projects

The federal and local New York City (NYC) governments are actively promoting Electric Vehicles (EVs). This capstone project assesses the state of EV charging infrastructure in NYC and its readiness for EV growth. NYC faces unique challenges due to its dense population and limited space for infrastructure. There's a significant disparity between the number of gas pumps and fast EV chargers in the city, with only 170 Level 3/DC (Direct Current) Fast Chargers publicly available. These Level 3 chargers are most important because they can charge an EV in 15 minutes; Level 2 chargers, also considered in the analysis, take …

Review Of The Book The Fight Against Book Bans: Perspectives From The Field, John A. Drobnicki

Publications and Research

Review of the book The Fight against Book Bans: Perspectives from the Field, edited by Shannon M. Oltmann.

Personalized Roadmaps For Returning Results From Digital Phenotyping, Kristin Marie Kostick-Quenet, John Herrington, Eric A Storch

Center for Medical Ethics and Health Policy Staff Publications

No abstract provided.

The Black Map Project: A Black People’S Epistemology Of Healing, Britton Williams

Dissertations, Theses, and Capstone Projects

This work is a love letter to Mary Turner and her descendants, by which I mean all Black people, that lifts recipes and roadmaps of Black creative healing and liberatory praxes. It is a freedom dream (Kelley, 2002) that dares to (re)imagine mental health care by holding Black healing and liberation centrally in mind. I do not seek to prove through this work but rather to provoke [thought|action|repair]. In this work, I unsettle prescribed notions of therapy that have long dismissed/erased/ignored the needs and [therapeutic] practices of Black people. The Black MAP Project resists epistemologies of ignorance (Mills, 2022)—born in …

Veterans Health Administration Enrollees’ Choice Of Care Setting Relates To The Expansion Of Care Options: Evidence From Screening Colonoscopies Before And After The Mission Act, Chase S Eck, Cheng Jiang, Laura A Petersen

Center for Medical Ethics and Health Policy Staff Publications

Objective: To estimate whether those enrolled in the Veterans Health Administration (VHA) were less likely to use VHA-delivered colorectal cancer screening colonoscopies after the MISSION Act.

Data sources and study setting: Secondary data were collected on VHA-enrolled Veterans from FY2017-FY2021.

Study design: This retrospective cross-sectional study measured the volume and share of screening colonoscopies that were VHA-delivered over time and by drive time eligibility-defined as living more than 60 min away from the nearest VHA specialty-care clinic. We used a multivariable logistic regression to adjust for patient and facility factors.

Data extraction: Data were extracted for VHA enrollees (n = …

Should Secondary Pharmacogenomic Variants Be Actively Screened And Reported When Diagnostic Genome-Wide Sequencing Is Performed In A Child?, Jan M Friedman, Yvonne Bombard, Bruce Carleton, Amalia M Issa, Bartha Knoppers, Sharon E Plon, Vasiliki Rahimzadeh, Mary V Relling, Marc S Williams, Clara Van Karnebeek, Danya Vears, Martina C Cornel

Center for Medical Ethics and Health Policy Staff Publications

This white paper was prepared by the Global Alliance for Genomics and Health Regulatory and Ethics Work Stream's Pediatric Task Team to review and provide perspective with respect to ethical, legal, and social issues regarding the return of secondary pharmacogenomic variants in children who have a serious disease or developmental disorder and are undergoing exome or genome sequencing to identify a genetic cause of their condition. We discuss actively searching for and reporting pharmacogenetic/genomic variants in pediatric patients, different methods of returning secondary pharmacogenomic findings to the patient/parents and/or treating clinicians, maintaining these data in the patient's health record over …

Gene-Specific Acmg/Amp Classification Criteria For Germline Apc Variants: Recommendations From The Clingen Insight Hereditary Colorectal Cancer/Polyposis Variant Curation Expert Panel\, Isabel Spier, Xiaoyu Yin, Marcy Richardson, Marta Pineda, Andreas Laner, Deborah Ritter, Julie Boyle, Pilar Mur, Thomas V O Hansen, Xuemei Shi, Khalid Mahmood, John-Paul Plazzer, Elisabet Ognedal, Margareta Nordling, Susan M Farrington, Gou Yamamoto, Stéphanie Baert-Desurmont, Alexandra Martins, Ester Borras, Carli Tops, Erica Webb, Victoria Beshay, Maurizio Genuardi, Tina Pesaran, Gabriel Capellá, Sean V Tavtigian, Andrew Latchford, Ian M Frayling, Sharon E Plon, Marc Greenblatt, Finlay A Macrae, Stefan Aretz, Insight-Clingen Hereditary Colon Cancer/Polyposis Variant Curation Expert Panel

Center for Medical Ethics and Health Policy Staff Publications

Purpose: The Hereditary Colorectal Cancer/Polyposis Variant Curation Expert Panel (VCEP) was established by the International Society for Gastrointestinal Hereditary Tumours and the Clinical Genome Resource, who set out to develop recommendations for the interpretation of germline APC variants underlying Familial Adenomatous Polyposis, the most frequent hereditary polyposis syndrome.

Methods: Through a rigorous process of database analysis, literature review, and expert elicitation, the APC VCEP derived gene-specific modifications to the ACMG/AMP (American College of Medical Genetics and Genomics and Association for Molecular Pathology) variant classification guidelines and validated such criteria through the pilot classification of 58 variants.

Results: The APC-specific criteria …

Risk Factors For Childhood Brain Tumours: A Systematic Review And Meta-Analysis Of Observational Studies From 1976 To 2022, Felix M Onyije, Roya Dolatkhah, Ann Olsson, Liacine Bouaoun, Isabelle Deltour, Friederike Erdmann, Audrey Bonaventure, Michael E Scheurer, Jacqueline Clavel, Joachim Schüz

Center for Medical Ethics and Health Policy Staff Publications

BACKGROUND: Childhood brain tumours (CBTs) are the leading cause of cancer death in children under the age of 20 years globally. Though the aetiology of CBT remains poorly understood, it is thought to be multifactorial. We aimed to synthesize potential risk factors for CBT to inform primary prevention.

METHODS: We conducted a systematic review and meta-analysis of epidemiological studies indexed in the PubMed, Web of Science, and Embase databases from the start of those resources through 27 July 2023. We included data from case-control or cohort studies that reported effect estimates for each risk factor around the time of conception, …

Utility Of A Low-Cost 3-D Printed Microscope For Evaluating Esophageal Biopsies, Daniel G Rosen, Evandro Sobroza De Mello, Sadhna Dhingra, Sanford M Dawsey, Joe Knapper, Richard Bowman, Sharmila Anandasabapathy

Center for Medical Ethics and Health Policy Staff Publications

In this manuscript we assessed the utility of a low-cost 3D printed microscope to evaluate esophageal biopsies. We conducted a comparative analysis between the traditional microscope and our 3-D printed microscope, utilizing a set of esophageal biopsy samples obtained from patients undergoing screening endoscopy. Two pathologists independently examined 30 esophageal biopsies by light microscopy and digital images obtained using a low-cost 3D printed microscope (Observer 1 and 2). The glass slide consensus diagnosis was compared to the findings of 2 additional pathologist who independently just reviewed the digital images (Observer 3 and 4). The intra-observer agreement was substantial to almost …

2024 February, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for February of 2024.

Investigating The Effects Of Alcohol Consumption On Manual And Automated Driving: A Systematic Review, Miaomiao Dong, Yuni Lee, Jackie Cha, Gaojian Huang

Mineta Transportation Institute

There are direct correlations between drunk driving and car-related injuries, disabilities, and death. Autonomous vehicles (AVs) may provide useful driver support systems to prevent or reduce road accidents. However, AVs are not yet fully automated and require human drivers to take over the vehicle at times. Therefore, understanding how alcohol affects driving performance in both manual and automated driving is important because manual drives may offer insights into the takeover process in AVs. A systematic review of 53 articles from eight databases was conducted. Findings were categorized based on the human information processing model, which can be extended to the …

Forests Are Chill: The Interplay Between Thermal Comfort And Mental Wellbeing, Loïc Gillerot, Kevin Rozario, Pieter De Frenne, Rachel Oh, Quentin Ponette, Aletta Bonn, Winston T. L. Chow, Douglas Godbold, Matthias Steinparzaer, Daniela Haluza, Dries Landuyt, Bart Muys, Kris Verheyen

Research Collection College of Integrative Studies

As global warming and urbanisation intensify unabated, a growing share of the human population is exposed to dangerous heat levels. Trees and forests can effectively mitigate such heat alongside numerous health co-benefits like improved mental wellbeing. Yet, which forest types are objectively and subjectively coolest to humans, and how thermal and mental wellbeing interact, remain understudied. We surveyed 223 participants in peri-urban forests with varying biodiversity levels in Austria, Belgium and Germany. Using microclimate sensors, questionnaires and saliva cortisol measures, we monitored intra-individual changes in thermal and mental states from non-forest baseline to forest conditions. Forests reduced daytime modified Physiologically …

Determinants Of Referral Network Size For Screening Colonoscopies In The Veterans Health Administration After The Implementation Of The Mission Act, Chase S Eck, Vivian Ho, Cheng Jiang, Laura A Petersen

Center for Medical Ethics and Health Policy Staff Publications

Objective: To measure key characteristics of the Veterans Health Administration's (VHA) Community Care (CC) referral network for screening colonoscopy and identify market and institutional factors associated with network size.

Data sources: VHA electronic health records, CC claim data, and National Plan and Provider Enumeration System.

Study design: In this retrospective cross-sectional study, we measure the size of the VHA's CC referral networks over time and by VHA parent facility (n = 137). We used a multivariable linear regression to identify factors associated with network size at the market-year level. Network size was measured as the number of physicians who performed …

Containerization Of Seafarers In The International Shipping Industry: Contemporary Seamanship, Maritime Social Infrastructures, And Mobility Politics Of Global Logistics, Liang Wu

Dissertations, Theses, and Capstone Projects

This dissertation discusses the mobility politics of container shipping and argues that technological development, political-economic order, and social infrastructure co-produce one another. Containerization, the use of standardized containers to carry cargo across modes of transportation that is said to have revolutionized and globalized international trade since the late 1950s, has served to expand and extend the power of international coalitions of states and corporations to control the movements of commodities (shipments) and labor (seafarers). The advent and development of containerization was driven by a sociotechnical imaginary and international social contract of seamless shipping and cargo flows. In practice, this liberal, …

Dancing In The Heart Of The Empire, Talisa Feliciano

Dissertations, Theses, and Capstone Projects

Dancing in the Heart of the Empire is an urban ethnography of public transit space in New York City. The work is based on five years of research on the trains of the Metropolitan Transit Authority’s (MTA) subway system. This work primarily focuses on Black and brown youth dancers who perform on the subways. Combining participant observation, archival research, digital social media research, and interviews, the dissertation identifies dancing as a form of resistance to the racialized structure of the train space and New York City. Public transportation is the heartbeat of the city. It is a contested site of …

Normative Orientations To Housing Activism And The Uneven Path To Nonprofitization In New York City, 1964–1989, Andrew Wilkes

Dissertations, Theses, and Capstone Projects

What are the distinct contributions of normative orientations (including theological and ideological ones) in the public policy process? While the literature on policy formation in the past three decades has embraced at least some idea that ideology matters, little has focused on whether the content of their specific normative orientations leads groups to contribute to, and engage in, a policy process differently. By examining Paul Sabatier’s advocacy coalition framework in conversation with Rev. Dr. Gayraud Wilmore’s tripartite, theoethical framework of liberation, elevation, and survival, this dissertation contends that the normative commitments of advocacy stakeholders within New York City’s tenant movement …

Public Service Motivation And Job Satisfaction Amid Covid-19: Exploring The Effects Of Work Environment Changes, Seulki Lee, Chongmin Na

Research Collection School of Social Sciences

The COVID-19 pandemic has brought critical changes to job demands and resources, which in turn affect employee motivation and outcomes. This study explores how COVID-19–induced work intensity and COVID-19–related organizational support influence public service motivation (PSM) and job satisfaction. Using survey data from a nationally representative sample of 1,430 South Korean central government employees collected during the pandemic (May–June 2020), we find that COVID-19–induced work intensity is positively associated with PSM, which in turn has a positive association with job satisfaction. We also find that COVID-19–related organizational support has both direct and indirect associations with job satisfaction through PSM. These …