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Curvilinear Association Between Language Disfluency And Fmr1 Cgg Repeat Size Across The Normal, Intermediate, And Premutation Range, Jessica Klusek, Ann Porter, Leonard Abbeduto, Tatyana Adayev, Flora Tassone, Marsha R. Mailick, Anne Glicksman, Bridgette L. Tonnsen, Jane E. Roberts Aug 2018

Curvilinear Association Between Language Disfluency And Fmr1 Cgg Repeat Size Across The Normal, Intermediate, And Premutation Range, Jessica Klusek, Ann Porter, Leonard Abbeduto, Tatyana Adayev, Flora Tassone, Marsha R. Mailick, Anne Glicksman, Bridgette L. Tonnsen, Jane E. Roberts

Faculty Publications

Historically, investigations of FMR1 have focused almost exclusively on the clinical effects of CGG expansion within the categories of the premutation (55–200 CGG repeats) and fragile X syndrome (>200 CGG repeats). However, emerging evidence suggests that CGG-dependent phenotypes may occur across allele sizes traditionally considered within the “normal” range. This study adopted an individual-differences approach to determine the association between language production ability and CGG repeat length across the full range of normal, intermediate, and premutation alleles. Participants included 61 adult women with CGG repeats within the premutation (n = 37), intermediate (i.e., 41–54 repeats; n = 2), …

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Evidence That The Hormonal Contraceptive Pill Is Associated With Cosmetic Habits, Carlota Batres, Aurélie Porcheron, Gwenaël Kaminski, Sandra Courrèges, Frédérique Morizot, Richard Russell Aug 2018

Evidence That The Hormonal Contraceptive Pill Is Associated With Cosmetic Habits, Carlota Batres, Aurélie Porcheron, Gwenaël Kaminski, Sandra Courrèges, Frédérique Morizot, Richard Russell

Psychology Faculty Publications

Hormonal contraception is known to cause subtle but widespread behavioral changes. Here, we investigated whether changes in cosmetic habits are associated with use of the hormonal contraceptive pill. We photographed a sample of women (N = 36) who self-reported whether or not they use the contraceptive pill, as well as their cosmetic habits. A separate sample of participants (N = 143) rated how much makeup these target women appeared to be wearing. We found that women not using the contraceptive pill (i.e., naturally cycling women) reported spending more time applying cosmetics for an outing than did women who …

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Biological Stress Response And Cognitive Vulnerability To Depression In Adolescence, Bridget M. Brush Aug 2018

Biological Stress Response And Cognitive Vulnerability To Depression In Adolescence, Bridget M. Brush

College of Science and Health Theses and Dissertations

Depression is the leading cause of worldwide disability. Rates of Major Depressive Disorder (MDD) increase exponentially over the adolescent transition, suggesting adolescence represents a key period of risk for the onset of depression. Previous research has associated both biological stress response and cognitive vulnerability with symptoms of depression; however, there is little research examining the joint effects of these two risk factors and symptoms of depression, especially during adolescence. The present study examined the association between symptoms of depression and two established risk factors for depression: cognitive vulnerability, as measured by negative cognitive style, and biological stress response, as measured …

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An Examination Of The Reciprocal Association Of Collective Efficacy And Community Violence Exposure In Low-Resourced, Urban African American Adolescents, Christopher R. Whipple Aug 2018

An Examination Of The Reciprocal Association Of Collective Efficacy And Community Violence Exposure In Low-Resourced, Urban African American Adolescents, Christopher R. Whipple

College of Science and Health Theses and Dissertations

African American adolescents are exposed to community violence at alarming rates. Compared to Caucasian adolescents, African American adolescents are 112% more likely to be exposed to community violence and 6 to 9 times more likely to be victims of homicide. There are many risk factors and behavioral/emotional issues associated with community violence exposure. Collective Efficacy Theory posited that collective efficacy (i.e., social cohesion and informal social control) influence community violence, and that a reciprocal association exists between collective efficacy and community violence. While the influence of collective efficacy on community violence exposure is established, the influence of community violence exposure …

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Executive Functioning In Pediatric Youth: A Meta-Analysis, Draycen D. Decator Aug 2018

Executive Functioning In Pediatric Youth: A Meta-Analysis, Draycen D. Decator

College of Science and Health Theses and Dissertations

Executive functioning (EF) represents a set of cognitive skills that are important for daily functioning. EF can be influenced by a number of biopsychosocial factors, many of which are present in the pediatric population (i.e., youth with at least one medical condition). It is important to understand EF in this population as it affects aspects of their physical health (e.g., treatment adherence). Previous meta-analyses have been conducted to examine EF in the pediatric population, and they have generally found deficits in EF compared to healthy peers. However, these previous meta-analyses have only focused on specific medical conditions (e.g., pediatric youth …

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Bidirectional Relations Between Parenting And Behavior Problems From Age 8 To 13 In Nine Countries, Jennifer E. Lansford, W. Andrew Rothenberg, Todd M. Jensen, Melissa A. Lippold, Dario Bacchini, Marc H. Bornstein, Lei Chang, Kirby Deater-Deckard, Laura Di Giunta, Kenneth A. Dodge, Patrick S. Malone, Paul Oburu, Concetta Pastorelli, Ann T. Skinner, Emma Sorbring, Laurence Steinberg, Sombat Tapanya, Liliana Maria Uribe Tirado, Liane Peña Alampay, Suha M. Al-Hassan Aug 2018

Bidirectional Relations Between Parenting And Behavior Problems From Age 8 To 13 In Nine Countries, Jennifer E. Lansford, W. Andrew Rothenberg, Todd M. Jensen, Melissa A. Lippold, Dario Bacchini, Marc H. Bornstein, Lei Chang, Kirby Deater-Deckard, Laura Di Giunta, Kenneth A. Dodge, Patrick S. Malone, Paul Oburu, Concetta Pastorelli, Ann T. Skinner, Emma Sorbring, Laurence Steinberg, Sombat Tapanya, Liliana Maria Uribe Tirado, Liane Peña Alampay, Suha M. Al-Hassan

Psychology Department Faculty Publications

This study used data from 12 cultural groups in nine countries (China, Colombia, Italy, Jordan, Kenya, Philippines, Sweden, Thailand, and the United States; N = 1,298) to understand the cross‐cultural generalizability of how parental warmth and control are bidirectionally related to externalizing and internalizing behaviors from childhood to early adolescence. Mothers, fathers, and children completed measures when children were ages 8–13. Multiple‐group autoregressive, cross‐lagged structural equation models revealed that child effects rather than parent effects may better characterize how warmth and control are related to child externalizing and internalizing behaviors over time, and that parent effects may be more characteristic …

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The Influence Of Regional Stereotypes In Employee Selection, Brittani E. Plaisance Aug 2018

The Influence Of Regional Stereotypes In Employee Selection, Brittani E. Plaisance

Doctoral Dissertations

An individual’s social world is understood through categorizing other people as those within an individual’s own in-group and those without, or the out-group. Social cognitive theory suggests that individuals make decisions in social settings based on implicit social comparisons between these groups. Stereotypes are oversimplified beliefs about the members of a specific group and discrimination is the behavioral outcome based on held stereotypes. Discrimination based on race, ethnicity, age, and gender has dominated research in the realm of employee selection for the last twenty years. Researchers have demonstrated perceived and actual differences in various attributes by region of the United …

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Bivariate Latent Change Score Analysis Of Peer Relations From Early Childhood To Adolescence: Leading Or Lagging Indicators Of Psychopathology, Brent Ian Rappaport Aug 2018

Bivariate Latent Change Score Analysis Of Peer Relations From Early Childhood To Adolescence: Leading Or Lagging Indicators Of Psychopathology, Brent Ian Rappaport

Arts & Sciences Graduate Student Theses and Dissertations

Despite significant public health concerns, the association between problematic peer relations (e.g., bullying) and psychopathology remains unclear. Thus far research has suggested three possible models of this association: that peer relations lead, or are a risk factor for symptoms of psychopathology (interpersonal risk model); lag, or are a consequence of psychopathology (interpersonal scar model); or both lead and lag psychopathology (transactional model). We additionally propose and test the hypothesis that peer relations may be a leading or lagging indicator of psychopathology depending on the developmental period (developmental model). Measures of youth’s peer relations (as reported by a parent and teacher …

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Modeling Initial Participation Of Diverse Communities In Competitive Swimming, Dane W. Wolfrom, Emily J. Murray, Angela M. Dominguez Aug 2018

Modeling Initial Participation Of Diverse Communities In Competitive Swimming, Dane W. Wolfrom, Emily J. Murray, Angela M. Dominguez

International Journal of Aquatic Research and Education

This research note introduces the Initial Participation Model, which theorizes continued participation in a activity or group before individuals make commitment is a function of: enjoyment, feeling of inclusion, and/or involvement opportunities. The specific focus of this research is investigating how deficiency in enjoyment, feeling of inclusion, and involvement opportunities may discourage continuing participation in competitive swimming by underrepresented populations such as African American, Black, Hispanic, Latino, Native American, Pacific Islander and low-socioeconomic communities. Details explain how initial participation differs from other sport stages by emphasizing participation; relating to program instead of sport; and resetting each time an individual joins …

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The People We Like: Do Introversion-Extroversion And Commitment Affect Evaluation Of Potential Partners?, Naquan Ross Aug 2018

The People We Like: Do Introversion-Extroversion And Commitment Affect Evaluation Of Potential Partners?, Naquan Ross

Seton Hall University Dissertations and Theses (ETDs)

The present study assessed whether similarity of a hypothetical partner on Introversion-Extroversion, along with partner preference for long-term or short-term relationships, might vary according to participants’ own Introversion-Extroversion. MANOVA results suggest three important points. First, ratings by extrovert participants showed higher levels of romantic interest for extroverted, rather than introverted, hypothetical partners; introvert participants’ ratings did not differ between introvert and extrovert partners on this dimension. Second, the similarity of the participant and the hypothetical partner on Introversion-Extroversion appeared to influence interpersonal interest, romantic interest, and commitment potential. Last, the partner’s commitment level may drive participants’ non-platonic interest and potential …

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Biological And Behavioral Mechanisms Underlying Childhood Physical Abuse And Age-Related Disease: Borderline Personality Pathology And Inflammation, Christina Rae Di Iorio Aug 2018

Biological And Behavioral Mechanisms Underlying Childhood Physical Abuse And Age-Related Disease: Borderline Personality Pathology And Inflammation, Christina Rae Di Iorio

Arts & Sciences Graduate Student Theses and Dissertations

Background: The frequent comorbidity of psychiatric and physical health conditions may be partially attributable to early life stress-related changes in inflammatory signaling and behavior (e.g., borderline personality pathology, health behaviors) that reciprocally maintain and enhance their effects on overall health.Methods: Using data from older adults (n=1,630) who participated in the ongoing longitudinal St Louis Personality and Aging Network (SPAN) study, we examined associations between childhood physical abuse, borderline pathology, inflammation markers (i.e., interleukin 6, c-reactive protein), health behaviors, and physical health. Morning fasting serum IL-6 and CRP were assayed from a subset of participants (n=791). Borderline pathology factor scores were …

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The Role Of Personality In The Development Of Health Disparities During Late-Mid Life, Juliette Mcclendon Iacovino Aug 2018

The Role Of Personality In The Development Of Health Disparities During Late-Mid Life, Juliette Mcclendon Iacovino

Arts & Sciences Graduate Student Theses and Dissertations

Objectives: The current study examined race/gender disparities in initial levels and trajectories of self-reported physical and mental health, and health care utilization, as well as the impact of personality and stressful life events on race/gender disparities. We hypothesized that health disparities would remain stable or decrease over time; that at-risk personality traits (e.g., high neuroticism) would have a more robust negative impact on health for black participants; that trust would mediate racial disparities in health; and that personality traits would moderate the association between stressful life events and health trajectories differentially across race/gender. Methods: Analyses utilized the first six waves …

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The Bello Chavez Family: A Reflection Of Health In The Mexican American Community Through A Family Nursing Assessment, Vanessa Bello Chavez Aug 2018

The Bello Chavez Family: A Reflection Of Health In The Mexican American Community Through A Family Nursing Assessment, Vanessa Bello Chavez

Best Integrated Writing

Vanessa Bello Chavez provides an in-depth, personal look into the health problems that affect Hispanic families across the United States. The writing takes a personal view and makes it relatable to all.

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Best Integrated Writing 2018 - Complete Edition Aug 2018

Best Integrated Writing 2018 - Complete Edition

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. The journal is published annually by the Wright State University Department of English Language and Literatures.

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Network Changes Associated With Transdiagnostic Depressive Symptom Improvement Following Cognitive Behavioral Therapy In Mdd And Ptsd, Steven Bruce, Zhen Yang, Shi Gu, Nicolas Honnorat, Kristin Linn, Russell Shinohara, Irem Aselcioglu, Desmond Oathes, Christos Davatzikos, Theodore Satterthwaite, Danielle Bassett, Yvette Sheline Aug 2018

Network Changes Associated With Transdiagnostic Depressive Symptom Improvement Following Cognitive Behavioral Therapy In Mdd And Ptsd, Steven Bruce, Zhen Yang, Shi Gu, Nicolas Honnorat, Kristin Linn, Russell Shinohara, Irem Aselcioglu, Desmond Oathes, Christos Davatzikos, Theodore Satterthwaite, Danielle Bassett, Yvette Sheline

Psychology Faculty Works

Despite widespread use of cognitive behavioral therapy (CBT) in clinical practice, its mechanisms with respect to brain networks remain sparsely described. In this study, we applied tools from graph theory and network science to better understand the transdiagnostic neural mechanisms of this treatment for depression. A sample of 64 subjects was included in a study of network dynamics: 33 patients (15 MDD, 18 PTSD) received longitudinal fMRI resting state scans before and after 12 weeks of CBT. Depression severity was rated on the Montgomery-Asberg Depression Rating Scale (MADRS). Thirty-one healthy controls were included to determine baseline network roles. Univariate and …

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Wellness And Karate, Cristina Kumpf Aug 2018

Wellness And Karate, Cristina Kumpf

Electronic Theses and Dissertations

The promotion of wellness is an integral part of the counseling field and is considered to be a central focus to the counseling process (Barden, Conley, & Young, 2015; Myers, 1992). The counseling profession adopted the concept of wellness because it harmonizes with many of the founding principles of the ACA and is seen as a process of questing toward optimal health and well-being in body, mind, and spirit (Barden, Conley, & Young, 2015; Myers, 1992; Myers, Sweeney, & Witmer, 2000). Additionally, ACA Code of Ethics (2014) state that counselors “engage in self-care activities to maintain and promote their own …

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Psychological And Family Variables Associated With The Treatment Of Pediatric Idiopathic Pain, Rachael Hoffman Aug 2018

Psychological And Family Variables Associated With The Treatment Of Pediatric Idiopathic Pain, Rachael Hoffman

Electronic Theses and Dissertations

The present study examined variability in treatment outcomes of children with idiopathic chronic pain. Specifically, the biopsychosocial model was used as a framework to consider the way that symptoms of depression and anxiety as well as parent response to pain contributed to the change in a child’s confidence in participating in daily activities following treatment in an inpatient chronic pain treatment program.

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The Impact Of Mother And Father Stress On Child Externalizing Behaviors, Allison Mccobin Aug 2018

The Impact Of Mother And Father Stress On Child Externalizing Behaviors, Allison Mccobin

Electronic Theses and Dissertations

The impact of parental stress on child behavioral problems has often been examined through research. A large majority of research indicates a strong correlation between parenting stress and an increase in child behavioral difficulties. However, most studies have focused only on the impact that one parent’s stress has on the child’s behavior, rather than both or comparing the two. Using two separate cross-lagged structural equation models, data from the Fragile Families Child and Wellbeing Study (N = 1010) were analyzed to examine the differences between mother and father parenting stress on child externalizing behavior problems over time (ages three and …

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The Zombie Apocalypse Has Already Happened: Queering Subjectivity In Zombie Film, Jessica Dunn Aug 2018

The Zombie Apocalypse Has Already Happened: Queering Subjectivity In Zombie Film, Jessica Dunn

Electronic Theses and Dissertations

This dissertation traces the encounter between psychology as a human science and the viral zombie film genre using the collaborative works of Deleuze and Guattari in conjunction with the queer anti-humanist theories of Colebrook and Halberstam. I interwove thematic (i.e. plot, dialogue, character development) and cinematographic (i.e. shot composition, editing, lighting, musical score) analyses of fourteen viral zombie films with theoretical arguments regarding the deterritorialization of the human subject and its relevance to psychology as a human science. The films were selected from the plethora of viral zombie films released after the turn of the 21st century. The selection was …

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Back In The Closet: A Queer-Modified Interpretive-Phenomenological Analysis Of Gay Men Creating An Identity Through Clothing, Jose Arroyo Aug 2018

Back In The Closet: A Queer-Modified Interpretive-Phenomenological Analysis Of Gay Men Creating An Identity Through Clothing, Jose Arroyo

Electronic Theses and Dissertations

How one dresses comprises their personal style, which subsequently informs one’s orientation to the world. Clothing is a global practice that demarcates our experience of self, others, and the world; and—as we are swathed in clothing since birth—those experiences are primarily split among gendered lines. Using Merleau-Ponty (2014/1945), I reconceptualize how clothing can be understood as inseparable from our body, and I use Deleuze and Guattari (1987/1980) to illustrate how clothing augments our embodied experience to produce a process of identification with our style. I also draw from queer theorists (Ahmed, 2006; Halberstam, 2011) to illustrate how we can disrupt …

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Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen Aug 2018

Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen

The Goose

Review of Daniel Coleman's Yardwork: A Biography of an Urban Place.

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Developmental Seizures And Mortality Result From Reducing Gabaa Receptor Α2-Subunit Interaction With Collybistin, Rochelle M. Hines, Hans Michael Maric, Dustin J. Hines, Amit Modgil, Patrizia Panzanelli, Yasuko Nakamura, Anna J. Nathanson, Alan Cross, Tarek Deeb, Nicholas J. Brandon, Paul Davies, Jean-Marc Fritschy, Hermann Schindelin, Stephen J. Moss Aug 2018

Developmental Seizures And Mortality Result From Reducing Gabaa Receptor Α2-Subunit Interaction With Collybistin, Rochelle M. Hines, Hans Michael Maric, Dustin J. Hines, Amit Modgil, Patrizia Panzanelli, Yasuko Nakamura, Anna J. Nathanson, Alan Cross, Tarek Deeb, Nicholas J. Brandon, Paul Davies, Jean-Marc Fritschy, Hermann Schindelin, Stephen J. Moss

Psychology Faculty Research

Fast inhibitory synaptic transmission is mediated by γ-aminobutyric acid type A receptors (GABAARs) that are enriched at functionally diverse synapses via mechanisms that remain unclear. Using isothermal titration calorimetry and complementary methods we demonstrate an exclusive low micromolar binding of collybistin to the α2-subunit of GABAARs. To explore the biological relevance of collybistin-α2-subunit selectivity, we generate mice with a mutation in the α2-subunit-collybistin binding region (Gabra2-1). The mutation results in loss of a distinct subset of inhibitory synapses and decreased amplitude of inhibitory synaptic currents. Gabra2–1 mice have a striking phenotype characterized by increased susceptibility to seizures and early mortality. …

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Parental Stress, Anxiety, And Depression And Child Emotional Intelligence In Children With 22q11.2 Deletion Syndrome, Megan A. Goldfarb Aug 2018

Parental Stress, Anxiety, And Depression And Child Emotional Intelligence In Children With 22q11.2 Deletion Syndrome, Megan A. Goldfarb

LSU New Orleans Theses and Dissertations

Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) have serious medical, psychological, and behavioral symptoms that are stressful to their parents. Higher general intelligence quotients (IQ) and emotional intelligence (EI) in children could allay parental stress. Self-reported stress, anxiety, and depression were measured in parents of children with 22q11.2DS (n=42) and a healthy control group (n=20) in relation to children’s IQ and EI. Children with 22q1.2DS had lower IQ and EI scores. Parental groups did not differ in their reported stress, anxiety, or depression. Children’s IQ and EI levels did not relate to parental measures of affect even in the 22q11.2DS …

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A Longitudinal Examination Of The Association Between Contextual Stress, Parenting, And School Readiness, Jessica M. Grande Aug 2018

A Longitudinal Examination Of The Association Between Contextual Stress, Parenting, And School Readiness, Jessica M. Grande

LSU New Orleans Theses and Dissertations

Contextual stress has been associated with poor school readiness skills during early childhood. This study evaluated mechanisms by which parent’s exposure to poverty-related contextual stressors influence the acquisition of school readiness skills from child age 2 to 4 among 167 parent-child dyads. Parent report of contextual stress and observational measures of parenting quality were collected during the children’s 2-year-old assessment. Teacher reports and children’s scores on school readiness tasks were collected during the 4-year-old assessment. Two approaches were used to understand the process by which contextual stressors influences school readiness; the accumulation of stressors approach and the constellations of stressors …

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Bubble Stream Production By Belugas (Delphinapterus Leucas), Megan Slack Aug 2018

Bubble Stream Production By Belugas (Delphinapterus Leucas), Megan Slack

Theses

Bubble stream production in belugas has been poorly characterized and its function is not well understood. I examined behavioral states when producing bubble streams (“bubbling”), and when bubbling calls, to determine whether bubbling was significantly associated with a particular call category or behavioral state. Using 19 hours of video and audio recordings collected over a two-day period, I quantified bubble streams of a 4-month old calf and an unrelated adult female housed together. Based on the overall activity budgets and pool of vocalizations for both animals, I calculated the expected counts of bubble streams with and without vocalizations, assuming that …

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Attitudinal, Normative, And Resource Factors Affecting Psychologists’ Intentions To Adopt An Open Data Badge: An Empirical Analysis, Lindsey M. Harper, Youngseek Kim Aug 2018

Attitudinal, Normative, And Resource Factors Affecting Psychologists’ Intentions To Adopt An Open Data Badge: An Empirical Analysis, Lindsey M. Harper, Youngseek Kim

Librarian Research

The purpose of this research is to investigate the attitudinal, normative, and resource factors affecting psychologists’ adoption of an open data badge. The theory of planned behavior was employed to demonstrate how these factors influence behavioral intentions to adopt an open data badge. This research used a survey method to examine to what extent those attitudinal, normative, resource factors influence psychologists’ behavioral intentions to adopt an open data badge, and therefore engage in data sharing behaviors. A national survey (n = 341) across the field of psychology showed that perceived benefit and perceived risk had significant positive and negative relationships …

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Understanding The Relationship Between Positive Affect And Cortisol In Lung Cancer Patients., Lauren Ann Zimmaro Aug 2018

Understanding The Relationship Between Positive Affect And Cortisol In Lung Cancer Patients., Lauren Ann Zimmaro

Electronic Theses and Dissertations

Positive psychobiological processes within lung cancer patients are drastically understudied. This dissertation explores the nature of positive affect (PA) and potential associations with diurnal cortisol among lung cancer patients, given the prognostic significance of diurnal cortisol rhythms. Theoretical underpinnings and current literature involving PA, cancer, and diurnal cortisol are first reviewed. An original integrated model of PA and cortisol among cancer patients is then presented, from which the proposed dissertation study and analyses are derived. Sixty-one non-small cell lung cancer patients provided self-report assessment of mood (PANAS PA and NA subscales, CES-D PA subscale), medical and demographic characteristics, and 10-day …

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Video Prompting Delivered Via Augmented Reality To Teach Transition-Related Math Skills To Adults With Intellectual Disabilities, Giulia Cacciatore Aug 2018

Video Prompting Delivered Via Augmented Reality To Teach Transition-Related Math Skills To Adults With Intellectual Disabilities, Giulia Cacciatore

Theses and Dissertations

The purpose of this study was to determine the effectiveness of a video-based instruction packet as a method of teaching math-based vocational skills delivered through augmented reality to three adults with intellectual disabilities. The dependent variable was the percentage of steps performed correctly to solve each selected type of math problem. The independent variable was the video-based math intervention delivered via augmented reality, which modeled the individual steps for solving three different multi-step math problems: (1) adjusting a recipe to serve a different number of people, (2) calculation of salary, (3) calculation of unit prices. Visual and statistical analysis demonstrated …

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Understanding The Student Intern's Journey Through A Holistic Counseling Center: A Phenomenological Inquiry, John C. Harvey Aug 2018

Understanding The Student Intern's Journey Through A Holistic Counseling Center: A Phenomenological Inquiry, John C. Harvey

CUP Ed.D. Dissertations

Eight Counselors in training (CITs) were followed through their professional counseling internships in a holistic outpatient counseling center. All participants were similarly exposed to mindfulness activities including yoga, qigong, meditation, and auricular acupuncture over the course of a semester, then asked to respond to the research question: How do student interns of the study site perceive and describe their lived experience of mindfulness phenomena? Phenomenological methodology was applied to the study and data was gathered through focus group discussion and face-to-face interviews. CITs registered descriptions of mindfulness phenomenon with insight, depth, and meaning. Their descriptions were recorded, transcribed, coded, themed, …

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Application Of A Three-Lever Drug Discrimination Method To Differentiate The Interoceptive Stimulus Effects Of 3, 4-Methylenedioxypyrovalerone And 4-Methylmethcathinone In Male Sprague-Dawley Rats, Trent Bullock Aug 2018

Application Of A Three-Lever Drug Discrimination Method To Differentiate The Interoceptive Stimulus Effects Of 3, 4-Methylenedioxypyrovalerone And 4-Methylmethcathinone In Male Sprague-Dawley Rats, Trent Bullock

Masters Theses

Psychoactive “bath salts” represent a continuing drug abuse problem. The synthetic cathinones, 3, 4-methylenedioxypyrovalerone (MDPV) and 4-methylmethcathinone (4-MMC) are popular constituents of “bath salts” in the United States and the United Kingdom, respectively. Addiction to these substances has proven difficult to treat, possibly requiring targeted therapeutics. Drug discrimination is a preclinical assay that may aid in treatment development. Thus far, two-lever (drug vs no drug) discrimination studies have exhibited asymmetrical substitution patterns between 4-MMC and MDPV. Therefore, a three-lever discrimination method was employed in which 12 male Sprague-Dawley rats were trained to discriminate 0.5 mg/kg MDPV, 2.0 mg/kg 4-MMC, and …

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