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Articles 3931 - 3960 of 20695
Full-Text Articles in Entire DC Network
A Comparison Of Task-Based And Questionnaire Assessments Of Executive Control Aspects In Relation To Adolescent Marijuana Initiation, Ying Guo, Charles B. Fleming, Irina Patwardhan, Tiffany D. James, Jennifer Nelson, Kimberly A. Espy, Timothy D. Nelson, W. Alex Mason
A Comparison Of Task-Based And Questionnaire Assessments Of Executive Control Aspects In Relation To Adolescent Marijuana Initiation, Ying Guo, Charles B. Fleming, Irina Patwardhan, Tiffany D. James, Jennifer Nelson, Kimberly A. Espy, Timothy D. Nelson, W. Alex Mason
Department of Psychology: Faculty Publications
Prior research has linked deficits in executive control (EC) to marijuana use in adolescents but has relied either primarily on adolescent self-report of EC or tasked-based EC, and focused on limited aspects of EC, usually inhibitory control. We examined unique associations of three established aspects of EC (inhibitory control, working memory, and flexible shifting) assessed with both performance on laboratory tasks and self-report in relation to marijuana initiation. Participants were 260 youth (ages 14–18 years) from a small Midwestern city in the United States enrolled in the adolescent phase (beginning in 2017) of an ongoing study of EC development recruited …
Effects Of Neighborhood Disadvantage And Peer Deviance On Conduct Problems: Interactions With Age Of Onset, Courtney Marie Goetz
Effects Of Neighborhood Disadvantage And Peer Deviance On Conduct Problems: Interactions With Age Of Onset, Courtney Marie Goetz
LSU Master's Theses
Youth with conduct problems (CP) generally fall into two developmental classifications, child-onset and adolescent-onset, which exhibit different causal processes and life course trajectories. Research suggests that child-onset CP is more likely to be related to individual predispositions, while adolescent-onset CP is more associated with social factors, such as peer delinquency. Living in impoverished and disorganized neighborhoods increases the risk for associating with deviant peers. Thus, the current study tested the hypothesis that neighborhood factors would be more strongly associated with adolescent-onset CP than child-onset CP, which would be explained by a greater association with deviant peers. Linear and negative binomial …
Max And The Listening Tree, Paula Ray, Danny Reneau
Max And The Listening Tree, Paula Ray, Danny Reneau
Zea E-Books Collection
Max is a young man who lives with his grandmother. He is unhappy and upset, so he goes for a walk. His dad is in the army and his mom is a busy nurse. He is at a new school where kids make fun of his name. He wants to fly back to his old home and school. He wishes for someone to talk to. He sits down in the woods and his feelings come pouring out. Suddenly he hears from an old tree about deep roots and things always coming back. It’s his own tree for listening and for …
Cognitive Appraisal, Workplace Social Courage, And Psycap, Quinn Denny
Cognitive Appraisal, Workplace Social Courage, And Psycap, Quinn Denny
Doctoral Dissertations and Projects
This study responds to calls for empirical investigation of courage as well as the discovery of positive psychological capital (PsyCap) antecedents. Courage and PsyCap are considered positive constructs associated with beneficial workplace outcomes. As an example, Workplace Social Courage (WSC) predicts organizational citizenship behavior (OCB). PsyCap is robustly correlated with performance outcomes, well-being, and sustainability. For its societal appeal, courage is not yet robustly validated. Further, interventions have demonstrated resultant increases in PsyCap, yet little is known of its antecedent variables. Also, to be discovered, are what variables mediate WSC. These gaps in research present opportunity for additional empirical investigation …
Shame, Stigma, And Callousness: A Moderated Mediation Study Of Sex Offender Empathy Strength, Robert M. Ferow
Shame, Stigma, And Callousness: A Moderated Mediation Study Of Sex Offender Empathy Strength, Robert M. Ferow
Doctoral Dissertations and Projects
Callous, lacking sympathy, heartless, and cold are but a few synonyms for people that demonstrate a deficit in empathy. Psychologists, criminologists, and sociologists have tried to explain this phenomenon of callousness, or lack of empathy found in criminals for hundreds of years. Issues of definitions of empathy, personality disorders, character flaws, and even neurobiological issues have been studied in their relation to empathy. Theories of criminology have been presented to explain the reasons for lack of empathy. However, as of yet, no conclusive findings demonstrate the order or function in loss of empathy strength. This study will endeavor to describe …
Philosophical Psychopathology And Individuation: The Archetype Of The Self And Rediscovering Personality, Alyc Jordan-Crump Rideout
Philosophical Psychopathology And Individuation: The Archetype Of The Self And Rediscovering Personality, Alyc Jordan-Crump Rideout
Doctoral Dissertations and Projects
Psychopathology has been associated to personality in trait characteristics as a contributing factor to mental illness, but the degree to which personality development as an influence in mental pathologies remains under researched at a phenomenological level. Thus, leaving a significant gap in psychopathological clinical literature on the functional role personality development is associated with psychopathology. In the modern era, the medical symptomology model of mental illness set by the DSM serves as the justification for psychotropic medication prescription as well as the diagnostic criteria for mental pathology but, there is limitations to functional ideals of mental health based off diagnostic …
Lgbtq-Parent Families: Diversity, Intersectionality, And Social Context, Abbie E. Goldberg
Lgbtq-Parent Families: Diversity, Intersectionality, And Social Context, Abbie E. Goldberg
Psychology
Lesbian, gay, bisexual, queer, and trans (LGBTQ) parents become parents in a variety of ways, including via reproductive technologies, through foster care and adoption, and in the context of different-gender relationships. This review addresses research developments over the past 5–6 years, revealing that LGBTQ people continue to face barriers in becoming parents, especially those who are trans, of color, and have limited financial means. Bisexual and trans parents are increasingly centered in research, and have unique experiences of parenthood related to navigating (in)visibility and stigma in various contexts. Recent work has documented the impacts of sociopolitical events (e.g., COVID-19, the …
Cultural Factors Associated With Human Trafficking Of Girls And Women In Northern Tanzania: The Case Of Arusha Region, Rehema John Magesa
Cultural Factors Associated With Human Trafficking Of Girls And Women In Northern Tanzania: The Case Of Arusha Region, Rehema John Magesa
Dignity: A Journal of Analysis of Exploitation and Violence
Human trafficking is persistent in many regions of Tanzania despite different efforts to reduce the practice by the Government and other stakeholders. Girls and young women are more affected by this practice in violation of their human rights than men and boys. This study explored the cultural factors attributing to the trafficking of girls and women in Northern Tanzania. The study involved 400 girls and young women for a quantitative and qualitative study on cultural determinants of human trafficking. The study found the following cultural practices pushed girls and women towards situations in which they could be trafficked: female genital …
Inner Work Community: Shadow Work As Spiritual Formation, Michael Simmons
Inner Work Community: Shadow Work As Spiritual Formation, Michael Simmons
Doctor of Leadership
The NPO statement surrounding this doctoral project is that A theological, practical, and community-centered framework for shadow work is disconnected from Christian spiritual formation. This doctoral project is the culmination of a three-fold process: discovering the need for shadow work in the context of spiritual formation, designing multi-faceted virtually-based opportunities to address this need among individuals and groups, and delivering those opportunities via online courses, one-on-one shadow work, and digital content such as essays, articles, and podcasts. My vocational context is my unofficial organization, and MVP, Inner Work Community, which provides these opportunities. Inner Work Community is extended through partnerships …
Salty: A Diffractive Inquiry Of Visceral Knowing And Embodied Aesthetics, Mei Ling Chua
Salty: A Diffractive Inquiry Of Visceral Knowing And Embodied Aesthetics, Mei Ling Chua
Dissertations, Theses, and Capstone Projects
This dissertation takes a diffractive, onto-epistemological approach to everyday practices with salt in order to articulate an expanded understanding of meaning making and knowledge production. This research reckons with and challenges dominant modes of knowing that engage a Cartesian perspective to situate knowing as the exclusive domain of the mind in both form and topic of inquiry. This research acts simultaneously as both a direct practice of and metacognition about knowledge production by examining 1. the embodied (including sensory and emotional aspects) and 2. the relational (including interpersonal and socio-cultural) dimensions of experience as visceral knowing. This articulation of …
Confusion Of Tongues: Translation And Transfers Of Attachment In A Post-Monolingual Condition, Hiji Nam
Confusion Of Tongues: Translation And Transfers Of Attachment In A Post-Monolingual Condition, Hiji Nam
Dissertations, Theses, and Capstone Projects
“Confusion of Tongues” proposes an intersubjective, dialogic approach to translation, psycholinguistics, and patient and clinicians’ relationships to the “mother tongue” and secondary languages. By tuning in to linguistic and translational shifts, stutters, and gaps, the study presents a consideration of the challenges and rewards presented by what I call a “post-monolingual clinical condition.” An individual’s self-state in a specific language will be shadowed by the emotional history and associations one brings to that language, which will also ripple into the counter-transferential matrix—we might call this the “transference to language,” or attachment styles that manifest and repeat an individual’s forgotten libidinal …
Emotional Support Animal Partnerships: Behavior, Welfare, And Clinical Involvement, Jillian Ferrell, Susan L. Crowley
Emotional Support Animal Partnerships: Behavior, Welfare, And Clinical Involvement, Jillian Ferrell, Susan L. Crowley
Psychology Student Research
The present study gathered information about the characteristics of individuals and dogs in Emotional Support Animal (ESA) partnerships, instances of service-animal misrepresentation, animal welfare and behavior, dimensions of bond quality, and health professional involvement. Seventy-seven adults (53 female, 24 male) with a canine ESA were surveyed via Qualtrics panel services. Data were analyzed for descriptive data, as well as correlational analyses among variables. Participants reported high frequencies of misrepresentation of emotional support animals, access law violations, and problematic instances including ESAs with a history of aggression and times when participants were unable to care for their dog. The majority of …
Choline Supplementation Alters Hippocampal Cytokine Levels In Adolescence And Adulthood In An Animal Model Of Fetal Alcohol Spectrum Disorders, Jessica A. Baker, Tamara S. Bodnar, Kristen Breit, Joanne Weinberg, Jennifer D. Thomas
Choline Supplementation Alters Hippocampal Cytokine Levels In Adolescence And Adulthood In An Animal Model Of Fetal Alcohol Spectrum Disorders, Jessica A. Baker, Tamara S. Bodnar, Kristen Breit, Joanne Weinberg, Jennifer D. Thomas
Psychology Faculty Publications
Alcohol (ethanol) exposure during pregnancy can adversely affect development, with long-lasting consequences that include neuroimmune, cognitive, and behavioral dysfunction. Alcohol-induced alterations in cytokine levels in the hippocampus may contribute to abnormal cognitive and behavioral outcomes in individuals with fetal alcohol spectrum disorders (FASD). Nutritional intervention with the essential nutrient choline can improve hippocampal-dependent behavioral impairments and may also influence neuroimmune function. Thus, we examined the effects of choline supplementation on hippocampal cytokine levels in adolescent and adult rats exposed to alcohol early in development. From postnatal day (PD) 4-9 (third trimester-equivalent), Sprague-Dawley rat pups received ethanol (5.25 g/kg/day) or sham …
Gender And Deception: Moral Perceptions And Legal Responses, Gregory Klass, Tess Wilkinson-Ryan
Gender And Deception: Moral Perceptions And Legal Responses, Gregory Klass, Tess Wilkinson-Ryan
Georgetown Law Faculty Publications and Other Works
Decades of social science research has shown that the identity of the parties in a legal action can affect case outcomes. Parties’ race, gender, class, and age all affect decisions of prosecutors, judges, juries, and other actors in a criminal prosecution or civil litigation. Less studied has been how identity might affect other forms of legal regulation. This Essay begins to explore perceptions of deceptive behavior—i.e., how wrongful it is, and the extent to which it should be regulated or punished—and the relationship of those perceptions to the gender of the actors. We hypothesize that ordinary people tend to perceive …
A Novel Measure Of Narrative Self-Functioning And Its Role In The Transformative Potential Of Psychedelic Experience Across Clinical And Non-Clinical Participants, Nicole M. Amada
Dissertations, Theses, and Capstone Projects
The eudaimonic field of well-being is founded on the idea that self-knowledge and the realization of one’s potential is at the heart of what it means to strive for well-being. While the “self” is at the core of this perspective, theories derived from this field have yet to incorporate neurocognitive conceptualizations of the self, and account for the collection of self-referential cognitions that influence striving for well-being. Such a theory and measure could fill this theoretical gap and be applied in person centered interventions to capture change in these processes over time. One such intervention utilizes psychedelic experience as a …
Biological Correlates Of The Effects Of Auricular Point Acupressure On Pain, Chao Hsing Yeh, Nada Lukkahatai, Xinran Huang, Hulin Wu, Hongyu Wang, Jingyu Zhang, Xinyi Sun, Thomas J Smith
Biological Correlates Of The Effects Of Auricular Point Acupressure On Pain, Chao Hsing Yeh, Nada Lukkahatai, Xinran Huang, Hulin Wu, Hongyu Wang, Jingyu Zhang, Xinyi Sun, Thomas J Smith
Faculty, Staff and Student Publications
BACKGROUND: To identify candidate inflammatory biomarkers for the underlying mechanism of auricular point acupressure (APA) on pain relief and examine the correlations among pain intensity, interference, and inflammatory biomarkers.
DESIGN: This is a secondary data analysis.
METHODS: Data on inflammatory biomarkers collected via blood samples and patient self-reported pain intensity and interference from three pilot studies (chronic low back pain, n = 61; arthralgia related to aromatase inhibitors, n = 20; and chemotherapy-induced neuropathy, n = 15) were integrated and analyzed. This paper reports the results based on within-subject treatment effects (change in scores from pre- to post-APA intervention) for …
Medical Assistance In Dying (Maid): Ethical Considerations For Psychologists, Gerald P. Koocher, G. Andrew H. Benjamin, Jonathan Bolton, Thomas G. Plante
Medical Assistance In Dying (Maid): Ethical Considerations For Psychologists, Gerald P. Koocher, G. Andrew H. Benjamin, Jonathan Bolton, Thomas G. Plante
Psychology
Significant ethical challenges arise when mental health practitioners care for patients who seek to accelerate their own dying for rational medically valid reasons. Current and proposed laws provide for medical assistance in dying (MAiD) in several U.S. jurisdictions, all of Canada, and several other nations. Differing provisions of these laws complicate their utility for some patients who seek aid in dying. Some extant laws include roles that mental health professionals might play in assessing patients’ competence or capacity to consent, mental illness, or other cognitive and behavioral factors. Practitioners who choose to accept roles in the MAiD process must consider …
Deliberate Erring Improves Far Transfer Of Learning More Than Errorless Elaboration And Spotting And Correcting Others' Errors, Sarah Shi Hui Wong
Deliberate Erring Improves Far Transfer Of Learning More Than Errorless Elaboration And Spotting And Correcting Others' Errors, Sarah Shi Hui Wong
Research Collection School of Social Sciences
Transfer of learning is a fundamental goal of education but is challenging to achieve, especially where far transfer to remote contexts is at stake. How can we improve learners’ flexible application of knowledge to distant domains? In a counterintuitive phenomenon termed the derring effect, deliberately committing and correcting errors in low-stakes contexts enhances learning more than avoiding errors. Whereas this benefit has been demonstrated with tests in domains similar to those in the initial learning task, the present set of three experiments (N = 120) investigated whether deliberate erring boosts far transfer of conceptual knowledge to dissimilar domains. Undergraduates studied …
No Fixed Limit For Storing Simple Visual Features: Realistic Objects Provide An Efficient Scaffold For Holding Features In Mind, Yong Hoon Chung
No Fixed Limit For Storing Simple Visual Features: Realistic Objects Provide An Efficient Scaffold For Holding Features In Mind, Yong Hoon Chung
Dartmouth College Master’s Theses
Prominent theories of visual working memory postulate that the capacity to maintain a particular visual feature is fixed. In contrast to these theories, recent studies have demonstrated that meaningful objects are better remembered than simple, non-meaningful stimuli. Here, we test whether this is solely because meaningful stimuli can recruit additional features — and thus more storage capacity — or whether simple visual features that are not themselves meaningful can also benefit from being part of a meaningful object. Across five experiments (each N=30) we demonstrate that visual working memory capacity for color is increased when colors are part of recognizable …
Examining Factors Related To Tobacco Treatment Engagement Among Tobacco Dependent Black/African American; Hispanic/Latino Cancer Patients: An Analysis Of Memorial Sloan Kettering Cancer Center’S Tobacco Treatment Program, Gleneara E. Bates-Pappas
Examining Factors Related To Tobacco Treatment Engagement Among Tobacco Dependent Black/African American; Hispanic/Latino Cancer Patients: An Analysis Of Memorial Sloan Kettering Cancer Center’S Tobacco Treatment Program, Gleneara E. Bates-Pappas
Dissertations, Theses, and Capstone Projects
Among patients diagnosed with cancer, persistent tobacco use is associated with adverse clinical outcomes such as worse treatment side effects, decreased effectiveness of cancer treatment (chemotherapy, radiotherapy, and surgery), all increasing risk of recurrence, second primary cancers, and poor survival. Despite the clinical importance of tobacco cessation in the context of high quality cancer care, engaging Black/African American and Hispanic/Latino cancer patients in tobacco treatment programs can be challenging. Prior studies with the general adult population demonstrate that Black/African American and Hispanic/Latino smokers are referred to and accept tobacco cessation treatment at lower rates compared to non-Hispanic White smokers. This …
Disrupted White Matter Microstructure Correlates With Impulsivity In Children And Adolescents With Bipolar Disorder, Tianjia Zhu, Alessio Simonetti, Minhui Ouyang, Sherin Kurian, Johanna Saxena, Jair C Soares, Kirti Saxena, Hao Huang
Disrupted White Matter Microstructure Correlates With Impulsivity In Children And Adolescents With Bipolar Disorder, Tianjia Zhu, Alessio Simonetti, Minhui Ouyang, Sherin Kurian, Johanna Saxena, Jair C Soares, Kirti Saxena, Hao Huang
Faculty, Staff and Student Publications
Altered white matter (WM) microstructure likely occurs in children with bipolar disorder (BD) with impulsivity representing one of the core features. However, altered WM microstructures and their age-related trendlines in children with BD and those at high-risk of developing BD, as well as correlations of WM microstructures with impulsivity, have been poorly investigated. In this study, diffusion MRI, cognitive, and impulsivity assessments were obtained from children/adolescents diagnosed with BD, offspring of individuals with BD (high-risk BD) and age-matched healthy controls. A novel atlas-based WM skeleton measurement approach was used to quantify WM microstructural integrity with all diffusion-tensor-imaging (DTI) metrics including …
A Preliminary Quranic Review Of Consciousness, Hana Naufanita, Nurwahidin Nurwahidin, Ghozali Ghozali
A Preliminary Quranic Review Of Consciousness, Hana Naufanita, Nurwahidin Nurwahidin, Ghozali Ghozali
Journal of Strategic and Global Studies
Consciousness is a classical discourse among scientists, philosophers, and theologians across time and space. It has become a hard problem from many angles: What it is? How do we approach it? How it is being discussed? What is the objective? Etc. The vast scope of the topic causes consciousness to become an intriguing topic to many disciplines. This paper offers multidisciplinary research to consciousness. This approach enables us to spot the problem, intersection, and division across disciplines. We found that there are convergences and divergences to consciousness as multidisciplinary object of study. First, consciousness is related to the mind, but …
Synchronised Transcranial Magnetic Stimulation For Substance Use-Disordered Veterans: Protocol For The Pilot Sham-Controlled Acceptability Trial, Jonathan Jampel, Mckenzie J. Quinn, Jamie L. Catalano, Chelsie B. Benca-Bachman, Leslie Brick, Noah S. Philip, Robert M. Swift
Synchronised Transcranial Magnetic Stimulation For Substance Use-Disordered Veterans: Protocol For The Pilot Sham-Controlled Acceptability Trial, Jonathan Jampel, Mckenzie J. Quinn, Jamie L. Catalano, Chelsie B. Benca-Bachman, Leslie Brick, Noah S. Philip, Robert M. Swift
Student Publications [Scholarly]
Introduction:
Substance use disorders (SUDs) take an enormous toll on US Veterans and civilians alike. Existing empirically supported interventions vary by substance and demonstrate only moderate efficacy. Non-invasive brain stimulation represents an innovative treatment for SUDs, yet aspects of traditional neurostimulation may hinder its implementation in SUD populations. Synchronised transcranial magnetic stimulation (sTMS) uses rotating rare earth magnets to deliver low-field stimulation synchronised to an individual's alpha peak frequency that is safe for at-home administration. The current trial aims to assess the acceptability and feasibility of sTMS, as well as the safety of at-home sTMS administration for substance-disordered Veterans.
Methods …
Lacan And The Algorithm, Clint Burnham
Lacan And The Algorithm, Clint Burnham
CLCWeb: Comparative Literature and Culture
Exploring the development of algorithms in Lacanian theory, specifically the "R schema" in the 1950s, I argue that psychoanalysis, read through contemporary debates about the "algorithmic cult" of Netflix and other avatars of popular culture, can be said to reveal the inhuman, machinic essence of subjectivity. The etiology of algorithms, mathemes, and other formulae and diagrams in Lacan’s oeuvre has been under-studied, in part because for some readers they are not as attractive as his more bravura flourishes of word play as exegetical excess, and in part because they derive largely from the ‘hard’ structuralist moment of his work in …
Cortical Connectomic Mediations On Gamma Band Synchronization In Schizophrenia, Xiaoming Du, Stephanie Hare, Ann Summerfelt, Bhim M Adhikari, Laura Garcia, Wyatt Marshall, Peng Zan, Mark Kvarta, Eric Goldwaser, Heather Bruce, Si Gao, Hemalatha Sampath, Peter Kochunov, Jonathan Z Simon, L Elliot Hong
Cortical Connectomic Mediations On Gamma Band Synchronization In Schizophrenia, Xiaoming Du, Stephanie Hare, Ann Summerfelt, Bhim M Adhikari, Laura Garcia, Wyatt Marshall, Peng Zan, Mark Kvarta, Eric Goldwaser, Heather Bruce, Si Gao, Hemalatha Sampath, Peter Kochunov, Jonathan Z Simon, L Elliot Hong
Faculty, Staff and Student Publications
Aberrant gamma frequency neural oscillations in schizophrenia have been well demonstrated using auditory steady-state responses (ASSR). However, the neural circuits underlying 40 Hz ASSR deficits in schizophrenia remain poorly understood. Sixty-six patients with schizophrenia spectrum disorders and 85 age- and gender-matched healthy controls completed one electroencephalography session measuring 40 Hz ASSR and one imaging session for resting-state functional connectivity (rsFC) assessments. The associations between the normalized power of 40 Hz ASSR and rsFC were assessed via linear regression and mediation models. We found that rsFC among auditory, precentral, postcentral, and prefrontal cortices were positively associated with 40 Hz ASSR in …
Skin Stories And Family Feelings: The Contradictions Of Skin Picking In Mother And Daughter, Katrina Jacinto
Skin Stories And Family Feelings: The Contradictions Of Skin Picking In Mother And Daughter, Katrina Jacinto
Crossings: Swarthmore Undergraduate Feminist Research Journal
Skin picking, otherwise known as dermatillomania, is considered to be a medical disorder by the DSM-5. However, the embodied experiences of skin picking in myself and my mother do not align with the neat definitions offered by psychiatry. Through autoethnographic material and an ethnographic interview with my mother, I argue that skin picking is a bodily technique that is pathologized through stigma. In particular, I suggest that skin picking reveals the body as a polyvalent entity, in which the same features and practices take on different meanings in different bodies. This frames the discrepancies between mine, and my mother's, experiences. …
Seeing And Unlearning Whiteness: A Mindfulness Workshop For Racial Justice, Emily Haranas
Seeing And Unlearning Whiteness: A Mindfulness Workshop For Racial Justice, Emily Haranas
Mindfulness Studies Theses
Racism is a deeply embedded, foundational aspect of American society. However, because the privilege of Whiteness insulates White individuals from the workings of systemic injustice and oppression and enables them to choose the conditions of their accountability in the movement for racial justice, many remain painfully blind to this fact. As such, there is a significant need for those who have been racialized White to develop a critical awareness of the powers and privileges ascribed to their racial identity. The working premise of this thesis is that mindfulness can assist White individuals in unlinking the socialized habits of mind that …
Enhancing The Quality Of Life For Senior Citizens: A Facilitator’S Guidebook For Mindful Music And Movement, Shannon Sexton
Enhancing The Quality Of Life For Senior Citizens: A Facilitator’S Guidebook For Mindful Music And Movement, Shannon Sexton
Mindfulness Studies Theses
Music appreciation and enjoyment enhance well-being throughout the lifespan. The challenges and constraints that people experience as they age can lead to lack of access to music, decreased physical activity, and fewer avenues for creative expression. Group music and movement interventions created for older populations offer opportunities for social connection and improved quality of life. Mindful practices add further benefit when combined with these interventions. Current available programs are scarce and most often do not encompass mixed modalities. In addition, the benefits of these programs do not show long-term sustainability. The purpose of this thesis is to explore the effects …
Does Preschool Executive Control Mediate The Impact Of Early Environmental Unpredictability And Deprivation On The General Factor Of Psychopathology A Decade Later?, Eric Phillips, Rebecca L. Brock, Tiffany D. James, Jennifer Nelson, W. Alex Mason, Kimberly Andrews Espy, Timothy D. Nelson
Does Preschool Executive Control Mediate The Impact Of Early Environmental Unpredictability And Deprivation On The General Factor Of Psychopathology A Decade Later?, Eric Phillips, Rebecca L. Brock, Tiffany D. James, Jennifer Nelson, W. Alex Mason, Kimberly Andrews Espy, Timothy D. Nelson
Department of Psychology: Faculty Publications
Background: Although deprivation has been consistently shown to increase risk for psychopathology through impaired executive control, the unique effects of other dimensions of early adversity, such as unpredictability, on executive control development are poorly understood. The current study evaluated whether deprivation and/or unpredictability early in life have unique effects on the general factor of psychopathology through impaired preschool executive control. Methods: Participants included 312 children (51% female) oversampled for greater sociodemographic risk. Preschool executive control was measured using a battery of nine developmentally appropriate executive control tasks. Dimensions of adversity were measured with observational and caregiver assessments, and …
Microrna-Mrna Networks Are Dysregulated In Opioid Use Disorder Postmortem Brain: Further Evidence For Opioid-Induced Neurovascular Alterations, Sandra L Grimm, Emily F Mendez, Laura Stertz, Thomas D Meyer, Gabriel R Fries, Tanmay Gandhi, Rupa Kanchi, Sudhakar Selvaraj, Antonio L Teixeira, Thomas R Kosten, Preethi Gunaratne, Cristian Coarfa, Consuelo Walss-Bass
Microrna-Mrna Networks Are Dysregulated In Opioid Use Disorder Postmortem Brain: Further Evidence For Opioid-Induced Neurovascular Alterations, Sandra L Grimm, Emily F Mendez, Laura Stertz, Thomas D Meyer, Gabriel R Fries, Tanmay Gandhi, Rupa Kanchi, Sudhakar Selvaraj, Antonio L Teixeira, Thomas R Kosten, Preethi Gunaratne, Cristian Coarfa, Consuelo Walss-Bass
Faculty, Staff and Student Publications
INTRODUCTION: To understand mechanisms and identify potential targets for intervention in the current crisis of opioid use disorder (OUD), postmortem brains represent an under-utilized resource. To refine previously reported gene signatures of neurobiological alterations in OUD from the dorsolateral prefrontal cortex (Brodmann Area 9, BA9), we explored the role of microRNAs (miRNA) as powerful epigenetic regulators of gene function.
METHODS: Building on the growing appreciation that miRNAs can cross the blood-brain barrier, we carried out miRNA profiling in same-subject postmortem samples from BA9 and blood tissues.
RESULTS: miRNA-mRNA network analysis showed that even though miRNAs identified in BA9 and blood …