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Articles 871 - 900 of 45506
Full-Text Articles in Entire DC Network
The Role Of Perceived Perpetrator Centrality In Intentions To Express Or Confront Sexist Behaviors, Anna G. Miller
The Role Of Perceived Perpetrator Centrality In Intentions To Express Or Confront Sexist Behaviors, Anna G. Miller
Theses/Capstones/Creative Projects
Confronting sexist acts (e.g., by saying, “That was sexist!”) has been empirically shown to reduce others’ sexist behaviors. However, bystanders are often reluctant to confront sexist acts, particularly when perpetrators of sexism are perceived as high in status. Prior studies have operationalized status in terms of organizational rank. However, individuals may also have status by virtue of their connections to other group members, which I investigate in the present study. Participants with full-time work experience (N = 451) were asked to read a vignette describing a sexist incident in which a male perpetrator of sexism had many (vs. few) …
“Am I A Criminal?”: How College Students Conceptualize Misconduct And Crime, Talia J. Norby
“Am I A Criminal?”: How College Students Conceptualize Misconduct And Crime, Talia J. Norby
Theses/Capstones/Creative Projects
Institutions of higher education play a critical role in regulating student behavior; however, existing research has given limited attention to how students themselves interpret conduct addressed through campus disciplinary systems. The present study examined how college students differentiate institutional misconduct from crime in university settings and whether those judgments are associated with perceptions of institutional legitimacy. Data was collected through an online Qualtrics survey administered to 146 students at the University of Nebraska at Omaha. Participants were presented with six vignette-based scenarios depicting campus-relevant behaviors and asked to classify each as criminal or non-criminal, rate its perceived severity, and identify …
Soft Skills In The Workplace: A Comparative Analysis, Meg Rothfuss
Soft Skills In The Workplace: A Comparative Analysis, Meg Rothfuss
Theses/Capstones/Creative Projects
Soft skills are defined as any non-technical ability related to how you do your work. While hard skills are commonly thought of first when it comes to job responsibilities, soft skills are increasingly important to the success of any role. Soft skills can be broken into the broad categories of cognitive, interpersonal, and intrapersonal skills. The goal of this study was to define the soft skill profiles of different industries and compare the similarities and differences across industries. To do this, an interview and survey were conducted including employees from a variety of industries. The interviews compared the IT and …
Self-Determination, Campus Involvement, And Disability Awareness Of Young Adults With Intellectual Disability, Zoe Bloecher
Self-Determination, Campus Involvement, And Disability Awareness Of Young Adults With Intellectual Disability, Zoe Bloecher
Honors Theses
This quantitative and qualitative study examined self-esteem; self-efficacy; self-determination; and disability awareness at the beginning and end of the semester in a sample of young adults with intellectual disability enrolled in a post-secondary education program. Participants’ weekly campus engagement in extracurricular activities during the semester was also tracked. The first goal of this study was to observe changes in self-determination satisfaction and frustration, self-esteem, self-efficacy, and disability awareness after one semester of enrollment in the program. There were 16 participants in the study who varied in their length of participation in the program. Dependent t-tests revealed a statistically significant decrease …
Choosing Death: The Moral Legitimacy Of Voluntary Active Euthanasia, Emma Rougeou
Choosing Death: The Moral Legitimacy Of Voluntary Active Euthanasia, Emma Rougeou
Honors Theses
During the last three decades, the issue of physician assisted suicide has captivated the interest of private citizens and state legislatures. Thinking about the matter of end-of-life concerns, particularly surrounding euthanasian (practices that hasten the deaths of suffering terminally ill people) have shifted. Views of private citizens and state-level legislation reflects a “slow shift to more permissive attitudes” (Cohen et al., 2012). Meanwhile, as recently as March 2026, state legislators in conjunction with the NY State Governor, passed a bill legalizing medical aid in dying for terminally ill patients. This thesis is intended to thoughtfully contribute to meaningful discourse on …
Sustainability Savvy: The Role Of Competence And Efficacy In Promoting Pro-Environmental Behavior, Lorenna Graham
Sustainability Savvy: The Role Of Competence And Efficacy In Promoting Pro-Environmental Behavior, Lorenna Graham
Environmental Studies Honors Projects
Combatting environmental issues requires both large-scale and individual change. While many understand that personal pro-environmental behavior (PEB) is necessary, individuals do not always engage in this behavior (Hines, 1986, Goh, 2022). Thus, there is a need to investigate psychological factors which encourage PEB. Prior research suggests competence and outcome efficacy as likely PEB predictors (Bentler, 2023, Lavergne & Pelletier, 2015, Priolo, 2016), while cognitive dissonance has been shown to both encourage and discourage PEB (Bouwman, 2022, Dickerson, 1992, Ehrich & Irwin, 2005). Study 1 investigates the relationship between cognitive dissonance and PEB with competence and outcome efficacy as potential moderators. …
Leading The Choreography: Preserving Creative Agency In Ai-Supported Problem-Solving, Mikhaila Ackerbauer
Leading The Choreography: Preserving Creative Agency In Ai-Supported Problem-Solving, Mikhaila Ackerbauer
Creativity and Change Leadership Graduate Student Master's Projects
As artificial intelligence tools become increasingly present in creative and problem-solving contexts, a critical question emerges: how can users engage with AI in ways that preserve rather than erode their own creative capacity? This project explores that question through research synthesis, practitioner conversations, coursework, international conference presentations, and the development of custom AI chatbots trained in the Creative Problem-Solving process. The central finding is a theoretical triangle comprising three interdependent capacities: autonomy, creative self-efficacy, and critical thinking. Grounded in Rhodes' (1961) Four P's framework, the triangle sits within the Person dimension. Convergent themes across the literature, practitioner conversations, and direct …
Why Don’T They Leave? : An Exploration Of Barriers That Prevent Women From Leaving Relationships Where They Experience Intimate Partner Violence, Jaelene Beltre
Why Don’T They Leave? : An Exploration Of Barriers That Prevent Women From Leaving Relationships Where They Experience Intimate Partner Violence, Jaelene Beltre
Theses and Dissertations
Relationships involving intimate partner violence (IPV) can often entail physical or verbal abuse from one individual to another in a romantic relationship. In a heterosexual relationship, the abuse most often occurs from the man to the woman. From an outside perspective, when considering the victims of abuse, one might ask simply, “Why don’t they leave?” However, the answer to this question, much like the abuse experienced in these dynamics, is nuanced. The present study is a literature review of studies meant to answer this very question. Abuse can often be some combination of physical, verbal, emotional, sexual, or financial. We …
Using Behavioral Monitoring To Assess Activity Patterns And Welfare Indicators In Captive Black Howler Monkeys (Alouatta Caraya), Ramiro Gomez Iii
Using Behavioral Monitoring To Assess Activity Patterns And Welfare Indicators In Captive Black Howler Monkeys (Alouatta Caraya), Ramiro Gomez Iii
Theses and Dissertations
This study examined activity patterns and potential welfare indicators in captive black howler monkeys (Alouatta caraya) using behavioral monitoring techniques. A monogamous pair housed indoors at Gladys Porter Zoo was observed using focal sampling methods, and a species specific ethogram was developed to systematically record behavior. A total of 1,750 minutes of data were collected over one year. Observed behaviors were categorized into five groups: affiliative, agonistic, stationary, locomotion, and stereotypic behaviors. Activity budgets were calculated to determine the proportion of time allocated to each behavioral category. Results indicated that affiliative behaviors, particularly physical contact, dominated the activity budget, while …
Keeping Track Of Time: Does Formal Education Of Temporal Symbols Refine People's Ability To Perceive Time?, Alyssa Gabrielle Smith
Keeping Track Of Time: Does Formal Education Of Temporal Symbols Refine People's Ability To Perceive Time?, Alyssa Gabrielle Smith
Undergraduate Honors Thesis Collection
While many studies find a relation between symbolic and nonsymbolic numerical abilities (e.g., Chen & Li, 2014), whether this relation is causal has been questioned. For example, does learning symbols refine nonsymbolic abilities (i.e., Refinement Hypothesis)? One study found that as children gained proficiency in their verbal counting abilities, their nonsymbolic numerical acuity increased (Shusterman et al., 2016), thus supporting the Refinement Hypothesis. As studies have found similar processing for numerical and temporal abilities (e.g., Walsh, 2003) and a similar relation between symbolic and nonsymbolic timing abilities has been found (e.g., Hamamouche & Cordes, 2020), it begs the question of …
Assessing Trauma Competence Among Title Ix Practitioners: Analyzing Self-Perceived Capability And Associated Factors, Aliena Hansen
Assessing Trauma Competence Among Title Ix Practitioners: Analyzing Self-Perceived Capability And Associated Factors, Aliena Hansen
Honors Program: Senior Projects (Public)
Sexual assault remains a persistent issue on college and university campuses, and the way institutions respond to survivors can significantly influence their well-being and willingness to seek support. Title IX Practitioners are often responsible for responding to reports of sexual misconduct, making trauma-informed approaches essential in their work. However, relatively little research has examined how practitioners perceive their own trauma-related capabilities. The present study examined self-perceived trauma competence among Title IX Practitioners and explored factors associated with differences in perceived competence. Participants completed a survey assessing their confidence in applying trauma-informed principles when working with complainants. Results indicated variability in …
Bridging The Gap: Educating Students On The Neurodiverse Experience, Riley Axtell
Bridging The Gap: Educating Students On The Neurodiverse Experience, Riley Axtell
Human Development and Family Sciences Undergraduate Honors Theses
Neurodivergent students face misunderstanding, stigma, and systemic barriers that impact academic and emotional well-being. The purpose of this study was to develop and implement a curriculum-based project designed to educate college students about neurodiverse experiences and improve knowledge, empathy, and understanding. The curriculum was administered in two formats: an in-person format with pre- and post-survey measurements and an online “choose your own adventure” implementation utilizing post-survey measurements. Participants engaged in simulated cognitive and sensory activities that represented experiences associated with dyslexia, ADHD, dysgraphia, and dyscalculia. Although limited by a small sample size, reliance on self-report measures, lack of a pre-survey …
Perceived Campus Safety And Psychological Flexibility As Moderators Of Posttraumatic Stress And Anxiety Following Indirect Exposure To School Gun Violence, Samara Trout
Honors Theses
The growing prevalence of gun violence in school settings within the United States, combined with extensive media coverage of these events, has heightened concerns regarding the psychological impact of indirect trauma exposure among students. The present study examined associations between indirect exposure to gun-based school violence and symptoms of posttraumatic stress and anxiety among undergraduate students at Western Michigan University (WMU). A secondary aim was to explore whether perceived safety and psychological flexibility/inflexibility moderated associations between indirect exposure and psychological distress. Using a cross-sectional correlational design, undergraduate students (N = 33) completed a self-report survey containing screening assessments, attention …
The Relationship Between Academic Stress And Sleep Quality Among University Students, Braden C. Baker
The Relationship Between Academic Stress And Sleep Quality Among University Students, Braden C. Baker
Finance Undergraduate Honors Theses
This research explores the significance of the question of whether academic stress affects the quality of sleep among university students across the globe. The following research will explore what can cause university students to experience high levels of academic stress, as well as explore ways that universities as a whole can assist with this stress. The research will also dive deeper into what actually causes these students to experience different qualities of sleep and whether high levels of academic stress are actually what causes low quality of sleep.
Throughout this research, a wide variety of studies and data from these …
A Meta-Analysis On Joinder Effects: Do They All Have The Same Magnitude?, Amelia M. Tisk
A Meta-Analysis On Joinder Effects: Do They All Have The Same Magnitude?, Amelia M. Tisk
Student Theses
The present meta-analysis examined whether different forms of joinder and procedural consolidation produce varying levels of prejudice in adjudicative decision-making. Although joinder procedures improve judicial efficiency, psychological research has suggested that combining charges, defendants, or plaintiffs within a single proceeding may increase conviction likelihood, liability judgments, and broader perceptions of wrongdoing. A random-effects meta-analysis was conducted across 22 independent study effects examining charge joinder, defendant consolidation, plaintiff consolidation, multiple-complainant procedures, and related aggregation paradigms. Effect sizes were converted to Pearson’s r whenever possible. Overall, procedural aggregation produced a moderate effect on adjudicative outcomes, r = .27, 95% CI [.22, .32]. …
Listening To Those Who Stay: Support Systems Influencing Special Education Teacher Retention, Carol Jean Dawson
Listening To Those Who Stay: Support Systems Influencing Special Education Teacher Retention, Carol Jean Dawson
Electronic Theses and Dissertations
Retention among special education teachers is a constant challenge across the country. Educators in these positions often have heavy workloads, emotionally demanding responsibilities, and complex caseloads leading to burnout and high turnover rates. Despite these challenges, most of them persevere in the field for extended periods, which indicate that robust and effective support systems are essential to aiding their commitment. In examining this phenomenon, this qualitative study focused on the lived experiences of six special education teachers who worked in the same school setting for a minimum of five years with the aim of identifying support structures that affect motivation, …
A Phenomenological Study: The Cultural Identity Of Black Transfer Students In Higher Education, Briana Lashon Levi
A Phenomenological Study: The Cultural Identity Of Black Transfer Students In Higher Education, Briana Lashon Levi
Electronic Theses and Dissertations
This qualitative phenomenological study explored the lived experiences of Black transfer students from the California Community College system to Southern Historically Black Colleges and Universities (HBCUs). Guided by two theoretical frameworks, Afrocentric Pedagogy and Black Identity Development Theory (BIDT), the study investigated how participants described and interpreted their cultural identity as they transitioned from a community college to a Southern HBCU. In this study, cultural identity was understood as a holistic construct that included students’ sense of belonging and their experiences of cultural affirmation, which functioned as core components rather than separate constructs from cultural identity. This research specifically focused …
Why Do Teachers Leave? Investigating Teacher Attrition In A New Orleans Charter School: A Qualitative Phenomenological Case Study, Carlos J. Machuca Rivera
Why Do Teachers Leave? Investigating Teacher Attrition In A New Orleans Charter School: A Qualitative Phenomenological Case Study, Carlos J. Machuca Rivera
Electronic Theses and Dissertations
The purpose of this phenomenological case study was to investigate the lived experiences of former teachers who worked at Goodlife Academy (GLA), a charter school in New Orleans, Louisiana, between 2019 and 2025, with particular attention to how teachers experienced job satisfaction and job dissatisfaction and how those experiences influenced their decisions to leave Teacher attrition—defined as educators leaving their school or the profession—has been associated with factors such as burnout, inadequate support, low compensation, and persistent challenges in addressing achievement gaps. Although these factors are well documented in the literature, many existing studies rely on quantitative methods and focus …
Factors Affecting Pedestrian-Vehicle Conflicts: An Empirical Analysis, Christo D. Jamo
Factors Affecting Pedestrian-Vehicle Conflicts: An Empirical Analysis, Christo D. Jamo
Honors Scholar Theses
The number of pedestrian deaths increased by 78% between 2009 and 2023, while other motor vehicle crash deaths increased by 13% in the same period [1]. To identify potential pedestrian safety measures, this study analyzed the effects of location-based demographics, pedestrian phasing type, and other physical infrastructure and behavior variables on the probability of pedestrian-vehicle conflicts at signalized intersections, which is a surrogate measure of crash risk. Data were collected from 55 intersections in Connecticut, and the pedestrian-vehicle interactions were classified by severity based on the Swedish Traffic Conflict Technique: undisturbed passage, potential conflict, minor conflict, or serious conflict. Because …
The Impact Of Framing Effects And Moral Values On Prosocial Engagement, Olajuwon Olagbegi
The Impact Of Framing Effects And Moral Values On Prosocial Engagement, Olajuwon Olagbegi
Dissertations
Framing effects can shape perceptions, beliefs and behavior, particularly in prosocial contexts. The current study examined how language framing (social justice, social activism, volunteerism) and moral values influence interest in prosocial engagement across low- and high-cost helping scenarios. Participants (N = 219) were randomly assigned to one of three framing conditions and reported willingness to help in both low- and high-cost situations. They also completed the Moral Foundations Questionnaire. Replicating prior work (Olagbegi and colleagues, 2024), participants were more willing to engage in low- than high-cost helping. Across conditions, social justice framing elicited the greatest willingness to help. Higher fairness …
Academic Anxiety, Anxiety Sensitivity, And General Mental Health In Collegiate Student-Athletes, Finley Gabrielle Elkins Sims
Academic Anxiety, Anxiety Sensitivity, And General Mental Health In Collegiate Student-Athletes, Finley Gabrielle Elkins Sims
Theses and Dissertations
Collegiate athletes’ mental health is on the decline, and they have unique experiences that can influence the prevalence of mental health struggles. This study examined academic anxiety, comorbid forms of anxiety, and predicting factors in 187 collegiate student-athletes across 29 U.S. colleges. Athletes had significantly higher levels of academic anxiety and general anxiety compared to a college nonathlete population. There were significant gender differences in athletes, with females having greater levels of anxiety sensitivity, academic anxiety, sport anxiety, general anxiety, depression, and a history of depression than male athletes. Gender, history of depression, anxiety sensitivity, and depression were significant predictors …
Parenthood And Mental Health Among University Populations In Sub-Saharan Africa: A Cross-Sectional Study, Tuwani A. Rasengane, Ngozika Esther Ezinne, Antor Ndep, Nnamdi John Eseme, Susarah Maria Richter, Kingsley E. Agho, Ebele Gertrude Ejidike, Michael Agyemang Kwarteng, Kelechukwu Enyinnaya Ahaiwe, Nnaemeka Meribe, Obed Adonteng-Kissi, Edith Daniel-Nwosu, Mchillary Ogiemudia Osamudiamen, Ike Onyebuchi Oforbuike, Grace Obumneke Ogbonna, Isaura Ilorena D.Alva Brito Dos Santos, Okechi Ulumma Amaechi, Ugochukwu E. Uzuegbu, Khathutshelo Percy Mashige, Uchechukwu Levi Osuagwu
Parenthood And Mental Health Among University Populations In Sub-Saharan Africa: A Cross-Sectional Study, Tuwani A. Rasengane, Ngozika Esther Ezinne, Antor Ndep, Nnamdi John Eseme, Susarah Maria Richter, Kingsley E. Agho, Ebele Gertrude Ejidike, Michael Agyemang Kwarteng, Kelechukwu Enyinnaya Ahaiwe, Nnaemeka Meribe, Obed Adonteng-Kissi, Edith Daniel-Nwosu, Mchillary Ogiemudia Osamudiamen, Ike Onyebuchi Oforbuike, Grace Obumneke Ogbonna, Isaura Ilorena D.Alva Brito Dos Santos, Okechi Ulumma Amaechi, Ugochukwu E. Uzuegbu, Khathutshelo Percy Mashige, Uchechukwu Levi Osuagwu
Research outputs 2022 to 2026
Background and Aims: This study examined the association between parenthood status and psychological well-being among university staff and students in sub-Saharan Africa (SSA). Methods: A cross-sectional, web-based survey was conducted across 22 universities in four SSA countries using convenience sampling. A total of 1189 university staff and students, including parents and non-parents, participated. Mental health outcomes were assessed using the Depression, Anxiety, and Stress Scales (DASS-21). Multinomial logistic regression models were used to examine associations between parenthood status and mental health outcomes after adjusting for sociodemographic and contextual factors. Results: Participants with children had lower odds of moderate depression (adjusted …
Attitudes, Behaviors, And Co-Workers Influence Of Those Who Provide Mental Health Support Services To Refugees And Immigrants., Irene Boamah
Attitudes, Behaviors, And Co-Workers Influence Of Those Who Provide Mental Health Support Services To Refugees And Immigrants., Irene Boamah
Doctor of Social Work Capstone Projects
ABSTRACT
ATTITUDES, BEHAVIORS, AND CO-WORKERS INFLUENCE OF THOSE WHO PROVIDE MENTAL HEALTH SUPPORT SERVICES TO REFUGEES AND IMMIGRANTS
Irene A. Boamah
April 3, 2026
Refugees and immigrants face a variety of mental health issues, including post-traumatic stress disorder (PTSD), depression, and anxiety. Despite these mental health issues, there is limited research examining the attitudes, behaviors and coworkers’ influence on those who provide mental health support services to this population. This study examines the relationships between the demographic and professional characteristics of mental health support service providers in Kentucky and the stigmas they may have toward refugees and immigrants.
A cross-sectional …
Christian-Based Community Engagement And Loneliness Among College Students, Ayodeji Fayemi
Christian-Based Community Engagement And Loneliness Among College Students, Ayodeji Fayemi
Master's Theses & Other Graduate Student Works
Loneliness among college students is a growing public health concern with significant implications for mental and physical well-being. Despite living in highly connected environments, many students report profound feelings of loneliness, which can exacerbate mental health challenges such as depression and anxiety. Loneliness also influences cognitive and social processes and has been linked to physical health risks, highlighting the need for effective interventions. This study examined whether Christian-based community engagement served as a protective factor against loneliness among college students. Grounded in Social Support Theory, the study assessed associations among loneliness, general social support, church-based support, religious coping, institutional integration, …
Building Collaborative Capacity For Coexistence With The Montana Beaver Working Group, Shane Randle
Building Collaborative Capacity For Coexistence With The Montana Beaver Working Group, Shane Randle
Graduate Student Portfolios, Professional Papers, and Capstone Projects
Despite beavers’ recent surge in popularity, prevailing negative attitudes and the persistence of beaver removal practices remain obstacles for those advocating living with beavers. The Montana Beaver Working Group (BWG) advances beavers’ role in ecological and community resilience through members’ collaborative efforts, including beaver-related restoration and conflict resolution projects. Bringing together people with diverse values and perspectives, the BWG builds collective understanding, develops a holistic vision for beavers in Montana, and supports members in pursuing it. As the group’s impacts and membership have grown, so too has their need to adapt. For my Civic Engagement Project, I strengthened the BWG’s …
Task-Dependent Modulation Of The N170 Erp Component In Facial Perception, Mary M. Krdikashyan
Task-Dependent Modulation Of The N170 Erp Component In Facial Perception, Mary M. Krdikashyan
Electronic Theses, Projects, and Dissertations
The N170 component plays a key role in face perception, but how attention influences it remains debated. In a series of five electroencephalography (EEG) experiments, we examined how attention to different facial features (holistic versus feature-based) affects the N170 amplitude. This study aims to determine whether perceptual competition explains these effects. In a preliminary study (Experiment 1), participants were primed to focus on either gender, age, emotional expression, race, or no specific task. This study showed a larger amplitude for gender and age, followed by emotion, with minimal differences for race, and no task was assigned. Since all these conditions …
The Relationship Between Telecommuting, Autonomy, And Burnout, Aniko Nagy
The Relationship Between Telecommuting, Autonomy, And Burnout, Aniko Nagy
Electronic Theses, Projects, and Dissertations
With flexible work arrangements becoming more common, the need to expand our understanding of the relationships between flexible work arrangements and employee health and wellbeing outcomes, such as employee burnout, continues to grow. The purpose of the present study is to explore the relationships between flexible work arrangements, autonomy, and employee burnout. The Job Demands-Resource (Bakker and Demerouti, 2007) and Conservation of Resources (Hobfall & Freedy, 2017) theories propose that job resources such as flextime, flexplace, and job autonomy are vital, and that the loss of or failure to acquire job resources can lead to stress and burnout. The Self …
Raising Resilient Children: Parent Video Guide To Support Children’S Emotional Development, Perla F. Nunez-Chavez
Raising Resilient Children: Parent Video Guide To Support Children’S Emotional Development, Perla F. Nunez-Chavez
Electronic Theses, Projects, and Dissertations
Social-emotional learning (SEL) in early childhood plays a critical role in
children’s ability to recognize emotions, regulate behavior, build relationships,
and succeed in academic settings. During the preschool years (ages 3–5),
children experience rapid emotional development and rely heavily on parents for
co-regulation, emotional modeling, and guidance. Research consistently shows
that when parents engage in emotion coaching practices, such as labeling
feelings, validating emotions, and modeling regulation strategies, children
demonstrate stronger emotional competence and improved developmental
outcomes. However, despite strong evidence supporting parent involvement in
SEL, many existing interventions are delivered through structured, in-person
programs that are often inaccessible to …
Face Representations In The Fusiform Face Area, Krisha Orgo
Face Representations In The Fusiform Face Area, Krisha Orgo
Electronic Theses, Projects, and Dissertations
Faces are among the most socially significant stimuli humans encounter, requiring recognition not just at the category level but at the level of individual identity. While the fusiform face area has been established as a dedicated region for face processing, whether it encodes distinct representations for different individuals or simply detects the presence of a face remains an open question. Evidence for identity-specific coding in the brain has come primarily from invasive single-neuron recordings in epilepsy patients, leaving open whether the same principles govern face processing in healthy populations. The present study addressed this gap using scalp electroencephalography to examine …
Investigating Fentanyl-Xylazine Interactions: Implications For Opioid-Induced Hyperalgesia And Affective Dysregulation In Rats, Alejandra R. Lujan
Investigating Fentanyl-Xylazine Interactions: Implications For Opioid-Induced Hyperalgesia And Affective Dysregulation In Rats, Alejandra R. Lujan
Electronic Theses, Projects, and Dissertations
The growing prevalence of fentanyl adulterated with xylazine presents a major public health concern, yet the behavioral and physiological effects of this combination remain poorly characterized. This study examined the effects of acute fentanyl administration, alone and in combination with xylazine, on opioid-induced hyperalgesia, affective behavior, and mortality in male and female Sprague-Dawley rats (n=80). Rats received four fentanyl injections (60 µg/kg) administered at 15-minute intervals, with or without xylazine (0, 0.1, 0.333, or 1.0 mg/kg), as well as a saline control condition. Pain sensitivity was assessed using a hot plate assay at 6.5, 12, 24, and 48 hours post-injection. …