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Personality-Based Clinical Predictors Of Transdiagnostic Suicidality In Emotional Disorders, Harshini Arun Jan 2026

Personality-Based Clinical Predictors Of Transdiagnostic Suicidality In Emotional Disorders, Harshini Arun

Masters Theses

No abstract provided.


Religiosity And Spirituality: The Mental Costs And Benefits Of Belief In A College Setting, Tyler Geis Jan 2026

Religiosity And Spirituality: The Mental Costs And Benefits Of Belief In A College Setting, Tyler Geis

Masters Theses

The relationship between religiosity and spirituality (R/S) with mental health has been widely discussed in more recent years. This thesis examines factors related to religiosity, spirituality, depression, anxiety, and stress, as well as how various stigmas toward mental health, mental health treatment, and mental health treatment seeking may relate to R/S and mental health. Previous literature has identified religious coping with hardship, positive and negative dimensions of sin and behavior, the structure of different religious groups, and overall spiritual wellbeing as factors related to R/S, mental health, and beliefs about mental health . However, most previous literature come to differing …


The Impact Of Medicaid Policy Limitations On Access To Eating Disorder Treatment: Uncovering The Consequences Of A System Built To Fail, Meghan Frost Jan 2026

The Impact Of Medicaid Policy Limitations On Access To Eating Disorder Treatment: Uncovering The Consequences Of A System Built To Fail, Meghan Frost

DSW Capstone Projects

Individuals who rely on Medicaid face major barriers when trying to access eating disorder (ED) treatment, reflecting broader patterns of structural disadvantage in publicly funded health care. Research shows delayed diagnosis, limited access to ED specialists, and frequent denials for recommended services. These gaps occur because Medicaid policies do not match the needs of evidence based ED care, resulting in delayed or incomplete care for many individuals with eating disorders.

This issue is highly relevant to social work practice because the policies shaping these barriers are complex and difficult for clients and ED providers to navigate. Social workers across clinics, …


Suicidal Mental Imagery And Its Association With Suicide-Related Disclosure And Suicidal Severity, Elisheva S. Rosensweig M.S. Jan 2026

Suicidal Mental Imagery And Its Association With Suicide-Related Disclosure And Suicidal Severity, Elisheva S. Rosensweig M.S.

Selected Full Text Dissertations, 2011-

People utilize two different modes of cognition, experiencing thoughts as mental images or verbal thoughts. Mental imagery tends to be more emotionally arousing and vivid than verbal thoughts, and most suicidal individuals report experiencing suicidal imagery in addition to verbal thoughts. Increasing evidence suggests that suicidal mental imagery is associated with heightened suicide risk, including greater likelihood of prior suicide attempts (e.g., Lawrence et al., 2021). However, suicide risk assessments primarily focus on verbal suicidal thoughts and rarely assess suicidal mental imagery, potentially contributing to the low rates of suicide-related disclosure and challenges identifying individuals at risk. The present study …


Beyond The Identified Patient: Sibling Attachment, Burden, And Coping In The Context Of Mental Illness, Blaire Fauser M.S. Jan 2026

Beyond The Identified Patient: Sibling Attachment, Burden, And Coping In The Context Of Mental Illness, Blaire Fauser M.S.

Selected Full Text Dissertations, 2011-

A “mental illness” is defined as a condition that causes clinically significant disturbance in cognition, emotion regulation, or behavior. Mental illness is growing increasingly more prevalent and has been found to not only impact the affected individual but also the broader family system. This study examined the impact of having a sibling with a mental illness on the non-diagnosed sibling. Specifically, the study focused on the relationship between siblings’ (sibling attachment), coping mechanisms, and caregiver burden. Previous research has shown that siblings of individuals with mental illness are at a higher risk of developing psychiatric conditions themselves, which is due …


Secure Base Script Behaviors In Romantic Couples As Predictors Of Romantic Relationship Quality, Ben N. Zigelstein Jan 2026

Secure Base Script Behaviors In Romantic Couples As Predictors Of Romantic Relationship Quality, Ben N. Zigelstein

Selected Full Text Dissertations, 2011-

Attachment representations guide expectations about the availability and responsiveness of attachment figures during times of need. These representations are shaped by early experiences of consistent, reliable caregiving and influence how individuals seek and receive support from close others across the lifespan. Secure base script knowledge, a temporal-causal sequence of events encompassing the essential elements of seeking and receiving support at times of need, is increasingly used to capture attachment representations. Research indicates that secure base script knowledge significantly predicts the quality of self-reported and observed romantic relationships. However, the extent to which secure base script behaviors (i.e., bidding for support, …


Ethnoracial Disparities In Treatment-Seeking Among Suicidal Adults: Stigma As A Mediator, Yiming Huang M.S. Jan 2026

Ethnoracial Disparities In Treatment-Seeking Among Suicidal Adults: Stigma As A Mediator, Yiming Huang M.S.

Selected Full Text Dissertations, 2011-

Despite the disproportionate increase in their suicide risk in recent years, ethnoracially minoritized individuals utilize mental health treatment less frequently than their non-Hispanic, White counterparts. Understanding the underlying mechanisms is crucial to identify strategies to mitigate such disparities. While mental health-related stigma has received attention as a potential mechanism, select types of stigma have been examined in isolation, leaving it unclear which forms of stigma are most relevant to the observed ethnoracial disparities in treatment-seeking among suicidal individuals. The current study assessed and examined a range of stigma constructs as potential mediators of ethnoracial differences in treatment-seeking outcomes among suicidal …


The Effects Of Anxiety On Adult Athletes And Approaches To Improving Performance And Well-Being, Taylor Glaspie-Walton Jan 2026

The Effects Of Anxiety On Adult Athletes And Approaches To Improving Performance And Well-Being, Taylor Glaspie-Walton

Theses and Dissertations

This systematic review examined the complex relationship between anxiety and sports performance in adult athletes, along with exploring effective approaches for enhancing both performance and psychological well-being. Through analysis of 18 studies spanning diverse sports and competitive levels, this research identifies key factors that influence anxiety responses and performance outcomes. Findings revealed that competition level, performance-goal discrepancies, and injury recovery significantly impact anxiety levels, with athletes' interpretations of anxiety symptoms proving more influential than symptom intensity alone. The research demonstrates that mental toughness and self-efficacy function as fundamental psychological resources, though their impact appears to plateau at elite competitive levels. …


Inclusive Psychology Pedagogy Is Linked To Increased Belonging And Reduced Prejudice Toward Consensually Non-Monogamous Relationships, Rose Bern, Rachel Dinero, Kate Linenbach, Amy Moors Jan 2026

Inclusive Psychology Pedagogy Is Linked To Increased Belonging And Reduced Prejudice Toward Consensually Non-Monogamous Relationships, Rose Bern, Rachel Dinero, Kate Linenbach, Amy Moors

Psychology Faculty Articles and Research

Students enrolled in an elective psychology course entitled Relationship Science, which emphasized inclusive curricula focused on relationship diversity, completed pre- and postcourse assessments of attitudes toward consensually nonmonogamous (CNM) relationships, relationship skills (e.g., constructive communication), and classroom belonging. Given the established literature on lesbian, gay, bisexual, transgender, queer+-inclusive pedagogy, attitudes toward lesbian, gay, bisexual, transgender, queer+ individuals were also measured. Comparisons of pre- and postcourse assessments revealed significant reductions in stigma toward individuals engaged in CNM, alongside increased acceptance of CNM relationships more broadly. Students also reported increases in relationship skills and classroom belonging over the course of the …


From Custody To Care: Understanding Mental Health And Recidivism In The Criminal Justice System, India Cox Jan 2026

From Custody To Care: Understanding Mental Health And Recidivism In The Criminal Justice System, India Cox

UROP Posters

Previous studies on genetic influences in mental health disorders have been shown to correlate with incarceration rates in families. Consequently, there are individuals within the criminal justice system under the clinical threshold of a mental health diagnosis; it has been found that almost half of the incarcerated population was arrested due to acting upon their mental health disorder, while 27 to 38 percent developed PTSD while imprisoned. Furthermore, the serious and exhausting cycle of recidivism within the criminal justice system highlights the failure to provide the necessary mental health treatment required to support rehabilitation while incarcerated and prevent reoffending upon …


Victimization Trauma And Eating Pathology; A Global Perspective, Madisyn E. Feliciano, Cate Morales, Kelsey Hagan Jan 2026

Victimization Trauma And Eating Pathology; A Global Perspective, Madisyn E. Feliciano, Cate Morales, Kelsey Hagan

UROP Posters

Introduction: Exposure to traumatic events is a well-established risk factor for eating pathology, including binge eating, purging, restricting, and excessive exercise. This association has been primarily explored in higher-income countries, like the United States. The goal of this study was to elucidate the associations among victimization trauma (physical assault, sexual assault, and other unwanted sexual experience assessed) exposure and (binge eating, purging, restriction and excessive exercise) in a global sample of women.

Methods: Participants were 2,458 women attending universities across seven countries (US, UK, Canada, Germany, Iran, Turkey, Colombia) who were recruited through their undergraduate participant pool. Students who completed …


East To West: Cultural Attitudes And The Perceptions Of Death, Hannah F. Ahmed Jan 2026

East To West: Cultural Attitudes And The Perceptions Of Death, Hannah F. Ahmed

UROP Posters

Death is a universal human experience, but cultures teach people to interpret it in different ways. These interpretations influence how individuals understand dying, how they cope with loss, what support looks like, and what meaning death makes in their lives. Eastern, spiritual, and religious traditions emphasize death as a natural transition or return to divinity rather than an endpoint, and as something one must prepare for. In these contexts, people often grow up hearing stories, prayers, and teachings that situate death within a broader journey. Because of this, death becomes something familiar and speakable rather than distant or frightening (Naderi-Afif …


Analyzing The Impact Of Positive Youth Development Programming On Youth Critical Consciousness, Jaylin Pate Jan 2026

Analyzing The Impact Of Positive Youth Development Programming On Youth Critical Consciousness, Jaylin Pate

UROP Posters

Youth Participatory Action Research (YPAR) is an approach to research where young people have active involvement in the research process. By uplifting youth voices and allowing the next generation to partner as co-researchers, YPAR strengthens their empowerment and agency (Anyon et. al, 2018). This study explored the impacts of YPAR programming on youth critical consciousness. Youth Voices, a community-based program, aims to support high school students in understanding positive youth development opportunities. Participants in the program attended weekly meetings and were compared to a control group with no similar intervention. Both groups completed Likert-scale surveys. Results that the intervention had …


Syllabus: Guttman Psyc101: Introduction To Psychology, Natalia Lara Gonzalez Jan 2026

Syllabus: Guttman Psyc101: Introduction To Psychology, Natalia Lara Gonzalez

Open Educational Resources

The present syllabus includes materials to be used for an introduction to psychology class. The topics range from basic cognitive, behavioral and developmental psychology to social sciences and nature vs. nurture debates. The syllabus also includes an abnormal psychology open access textbook where students can access details on mental health conditions which they present on at the end of the semester.


[Review Of The Book The Prescription-To-Prison Pipeline: The Medicalization And Criminalization Of Pain, By M. Smirnova], Hayley Jackey Jan 2026

[Review Of The Book The Prescription-To-Prison Pipeline: The Medicalization And Criminalization Of Pain, By M. Smirnova], Hayley Jackey

Sociology & Criminal Justice Faculty Publications

[Introduction] Smirnova’s The Prescription-to-Prison Pipeline offers a critical examination of the impacts of prescription drugs as well as the over-policing and policies created to push individuals into the carceral system rather than providing other options for assistance. Smirnova further captures the social inequalities of race and class of those encased in this pipeline. Within this understanding of the detriment that the system, medical providers, and society place on those who use substances, Smirnova’s use of interviews allows for a clear understanding of how these systems work in conjunction to uphold the pipeline.


Parental Distress, Coercive Control With Food, And Child Self-Regulation, Kattie Nguyen Jan 2026

Parental Distress, Coercive Control With Food, And Child Self-Regulation, Kattie Nguyen

UNF Graduate Theses and Dissertations

Self-regulation is the management of one's emotions, thoughts, and behaviors to adapt to a situation (Smith-Donald et al., 2007). During infancy and toddlerhood, parents foster self-regulation through co-regulation (e.g., sensitivity, responsiveness), helping children manage their emotions, behaviors, and thoughts (Butler & Randall, 2013). Parents who experience distress (e.g., depression, stress, anxiety) are more likely to use less responsive and harsher, controlling practices like coercive control. Coercive control with food is a practice where parents use food as threats or bribes to control their child’s emotions and behaviors (Vaughn et al., 2016). The present study examined the associations between parental distress, …


The Odyssey Of Emotion Regulation In Extremis: How Challenges Lead To Team States Through Regulation And Psychological Safety In Ice, Andres Kaosaar Jan 2026

The Odyssey Of Emotion Regulation In Extremis: How Challenges Lead To Team States Through Regulation And Psychological Safety In Ice, Andres Kaosaar

Graduate Studies Theses and Dissertations 2026

Isolated, confined, and extreme (ICE) teams experience challenges that require continuous emotional adaptation. Although emotion regulation (ER) has been recognized as critical for functioning in these contexts, little is known about how specific challenges shape regulatory responses, how team climate influences those responses, and how individual regulation accumulates into team-level outcomes. This dissertation develops and tests a multilevel framework linking challenge exposure, perceived psychological safety, individual ER, team emotions, and team viability in space analog environments. Data were collected from 36 crews (N = 184) participating in two-week missions at two space analog stations, yielding 2,577 daily observations and …


Internalized Shame, Self-Focused Attention, And Post-Event Processing In Everyday Social Anxiety, Wooje Lee Jan 2026

Internalized Shame, Self-Focused Attention, And Post-Event Processing In Everyday Social Anxiety, Wooje Lee

Graduate Studies Theses and Dissertations 2026

The purpose of this study was to investigate how emotional processes, represented by internalized shame and daily shame (from the emotion-focused therapy model), and cognitive processes, represented by self-focused attention and post-event processing (from cognitive-behavioral models), operate on a daily basis to contribute to social anxiety. Data collected from a sample of 39 individuals with high social anxiety via an online survey and daily diaries was analyzed using multilevel path analysis. The results showed that, at the within-person level, daily shame experienced during an important social interaction influenced self-focused attention during that same interaction and subsequent post-event processing, which in …


Development Of The Simultaneous Alcohol And Cannabis Use Expectancy Questionnaire (Sac-Eq), Shane D. Marohnic Jan 2026

Development Of The Simultaneous Alcohol And Cannabis Use Expectancy Questionnaire (Sac-Eq), Shane D. Marohnic

Graduate Studies Theses and Dissertations 2026

Background: Simultaneous alcohol and cannabis use (SAC/SAM), defined as using alcohol and cannabis at the same time so that their effects overlap, has been identified as a hazardous form of polysubstance use. Expectancies are a causal mechanism and can be changed with predictable reductions in substance use and associated consequences, yet only one measure has been developed to assess expectancies related to SAC. Due to limitations of the existing measure, this study sought to create a more comprehensive SAC expectancy scale. Method: Three phases of participants (Phase 1, N = 493; Phase 2, n = 4; Phase 3, n …


Perspectives Of Poetry: Peering Into Poetry And Aphasia, Kristian M. Perez Jan 2026

Perspectives Of Poetry: Peering Into Poetry And Aphasia, Kristian M. Perez

Graduate Studies Theses and Dissertations 2026

People with aphasia often experience significant barriers to communication, emotional expression, and participation in meaningful life activities following stroke or neurological injury. Although poetry and creative expression have been explored in broader therapeutic contexts, limited research has examined how people with aphasia perceive poetry. The purpose of this qualitative study was to explore the perspectives of people with aphasia regarding definitions of poetry, level of interest in poetry and the factors influencing said interest. Semi-structured interviews were conducted with adults with aphasia recruited through convenience sampling. Participants responded to questions before and after exposure to the poem Trust by Mark …


Independent And Interacting Effects Of Co-Presence And Social Media 'Likes' On Online Disinhibition, Margaret M. Doheny Jan 2026

Independent And Interacting Effects Of Co-Presence And Social Media 'Likes' On Online Disinhibition, Margaret M. Doheny

Graduate Studies Theses and Dissertations 2026

Social media platforms have fundamentally transformed interpersonal communication by creating environments in which behaviors are publicly reinforced through visible social feedback systems such as “likes.” Although prior research has linked online environments with increased disinhibition and negative behavior, existing literature has primarily focused on anonymity and invisibility as the primary mechanisms underlying these effects. However, the mechanistic role of physical and psychological co-presence in driving online disinhibition has received little empirical investigation. The central aim of the present study was to determine whether reduced social presence and the selective reinforcement of negative content contribute to online disinhibition and anticipatory reward-seeking …


Detecting Error In Ai-Generated Text: The Effects Of Authorship And Word Presentation Speed, Gabriela Flores Cruz Jan 2026

Detecting Error In Ai-Generated Text: The Effects Of Authorship And Word Presentation Speed, Gabriela Flores Cruz

Graduate Studies Theses and Dissertations 2026

The increased us of artificial intelligent (AI) chatbots powered by Generative Pre-trained Transformers has raised concerns about users’ ability to detect errors of AI-generated text. This dissertation examined how readers identify inconsistencies in AI-generated expository passages using the inconsistency detection paradigm from comprehension monitoring research. Across two experiments, it investigated whether perceived authorship and word presentation speed influenced inconsistency detection. Experiment 1 used a 3 (author: human, AI, no author) × 2 (inconsistency type: internal, external) between-subjects design. Perceived authorship did not significantly affect hit rates, sensitivity, or response bias. Exploratory analyses indicated that reading comprehension and working memory predicted …


The Role Of Alcohol Expectancies In The Relationship Between Social Anxiety And Protective Behavioral Strategies Among College Students, Jordan Ortman Jan 2026

The Role Of Alcohol Expectancies In The Relationship Between Social Anxiety And Protective Behavioral Strategies Among College Students, Jordan Ortman

Graduate Studies Theses and Dissertations 2026

College students with elevated social anxiety are at heightened risk for alcohol-related consequences despite not consistently reporting greater alcohol use. One potential explanation for this pattern is lower engagement in protective behavioral strategies (PBS). Social alcohol expectancies are relevant to PBS use because students with elevated social anxiety often expect alcohol to reduce social discomfort or facilitate social interaction, and these beliefs may correspond with lower use of strategies that constrain the pace or amount of drinking. The present study examined whether positive and negative social alcohol expectancies were intermediate variables in associations between social anxiety and three PBS domains: …


Improving Pediatric Emergency Department Lethal Means Safety Documentation Rates For Adolescents With Mental Health Concerns, Cassandra L. Stegall, Ana-Maria Mcgill, John Fanton, Paul C. Mullan Jan 2026

Improving Pediatric Emergency Department Lethal Means Safety Documentation Rates For Adolescents With Mental Health Concerns, Cassandra L. Stegall, Ana-Maria Mcgill, John Fanton, Paul C. Mullan

Department Psychiatry & Behavioral Science Faculty Publications

Introduction:

Lethal means safety counseling (LMSC) is recommended for children presenting to the emergency department (ED) for a mental health (MH) evaluation. Currently, no gold-standard guidelines exist for documenting LMSC in the ED.

Methods:

This quality improvement project was conducted in the ED of a tertiary children's hospital. Baseline data were analyzed for access to any LMSC documentation (ALD) for "firearms/guns," "sharps," or "medication," and for complete LMSC documentation (CLD) if access to all 3 types was documented. The first intervention period added open-ended screening questions about access to lethal means to the MH-licensed clinical social worker note template. Intervention …


Startle Habituation And Vagally Mediated Heart Rate Variability Influence The Use Of Emotion Regulation Strategies, Xiao Yang, Fang Fang, Angela Ximena Babb Jan 2026

Startle Habituation And Vagally Mediated Heart Rate Variability Influence The Use Of Emotion Regulation Strategies, Xiao Yang, Fang Fang, Angela Ximena Babb

Psychology Faculty Publications

Emotion regulation refers to the processes through which people modulate their emotional experiences and expressions, and difficulties in these processes underpin many forms of psychopathology. According to the process model, emotion regulation encompasses five classes of strategies, commonly grouped into antecedent-focused strategies (e.g., cognitive reappraisal) and response-focused strategies (e.g., expressive suppression). These strategies involve both explicit and implicit processes, which can be objectively assessed using physiological indices. The present study examined the effects of startle habituation and vagally mediated heart rate variability (vmHRV) on the use of cognitive appraisal and suppression. Forty-nine college-aged participants were recruited, and their resting heart …


Gaze Transition Entropy And Automation Trust In Multitasking Workspace, Yusuke Yamani, Austin Jackson, Tetsuya Sato, Feyishola Ashimi, Michael S. Politowicz, Eric T. Chancey, Makoto Itoh Jan 2026

Gaze Transition Entropy And Automation Trust In Multitasking Workspace, Yusuke Yamani, Austin Jackson, Tetsuya Sato, Feyishola Ashimi, Michael S. Politowicz, Eric T. Chancey, Makoto Itoh

Psychology Faculty Publications

Safe flight operation requires visual scanning across multiple displays in a cockpit, which collectively represent the state of the aircraft and supporting automation. Trust is a crucial factor that drives human-automation interaction, and recent work has suggested a relationship between an operator's visual attention and automation trust. One index that captures predictability of eye movements between different areas of interest is gaze transition entropy. The current work reanalyzed data from Sato et al., which examined eye movement patterns and trust in automation associated with the system monitoring task of the Multi-Attribute Task Battery. Results showed credible positive correlations between the …


Parental Psychological Distress And Perceived Child Externalizing Behaviors: Examining Mediators And Bidirectional Effects, Abigail J. Anderson, Christina M. Rodriguez, James M. Henson Jan 2026

Parental Psychological Distress And Perceived Child Externalizing Behaviors: Examining Mediators And Bidirectional Effects, Abigail J. Anderson, Christina M. Rodriguez, James M. Henson

Psychology Faculty Publications

Parental psychological distress is a commonly examined risk factor for the emergence of child problem behaviors, but the factors that contribute to that relationship—such as limited parental resources like greater social support and coping skills—have not been adequately explored, particularly with attention to potential bidirectional relations that incorporate child evocative effects. The current longitudinal study examined maternal and paternal psychological distress in relation to perceived child externalizing behaviors, considering parental resources as mediators within a bidirectional model. The sample included a racially and socioeconomically diverse group of 201 primiparous mothers and 151 fathers. Mothers and fathers reported their current psychological …


I Can't Stop: The Effects Of Psychological Climate For Overwork On Recovery Experiences, Jeffrey Drake Terry, Konstantin P. Cigularov Jan 2026

I Can't Stop: The Effects Of Psychological Climate For Overwork On Recovery Experiences, Jeffrey Drake Terry, Konstantin P. Cigularov

Psychology Faculty Publications

Recovery experiences are important for many health and well-being outcomes. One potential threat to an individual's recovery experiences in the workplace is psychological climate for overwork. The purpose of the present study was to examine the relationship between psychological climate for overwork and recovery experiences. Using a multi-wave research design (N = 202), we found that psychological climate for overwork had direct effects on psychological detachment and indirect effects on psychological detachment and relaxation through cognitive workaholism and work-recovery guilt. These results suggest that psychological climate for overwork may contribute to an individual's experience of cognitive workaholism and work-recovery guilt, …


Maternal Child Maltreatment And Intimate Partner Violence: Effects On Perceptions Of Infant Temperment And The Mediating Role Of Emotion Regulation And Responsiveness, Jewelian N. Fairchild, G. Anne Bogat, Amy K. Nuttall, Alytia A. Levendosky, Joseph S. Lonstein, Maria Muzik Jan 2026

Maternal Child Maltreatment And Intimate Partner Violence: Effects On Perceptions Of Infant Temperment And The Mediating Role Of Emotion Regulation And Responsiveness, Jewelian N. Fairchild, G. Anne Bogat, Amy K. Nuttall, Alytia A. Levendosky, Joseph S. Lonstein, Maria Muzik

Psychology Faculty Publications

Purpose

Maternal adverse experiences, such as maltreatment in childhood and later intimate partner violence (IPV) during pregnancy, can disrupt the mother-child relationship and influence maternal perceptions of infant temperament. The present study explored how these adversities influence mothers’ views of their infants’ temperaments and examined the role of maternal emotion regulation and responsiveness to their infants as mediators of these relationships.

Methods

Using data from a longitudinal study of highly stressed, vulnerable women, 355 mothers retrospectively reported on their own childhood maltreatment, as well as their experiences of IPV and emotion regulation during pregnancy. Maternal responsiveness was coded using mother-infant …


From Molecules To Minds: Integrative Multi-Omics In Psychiatry, Hossein Abbasi, Sage E. Hawn, Arash Javanbakht, Soraya Seedat, Kyle Bourassa, Sinead M. Sinnott, Antonia V. Seligowski, Sian Hemmings, Nathan A. Kimbrel, Alicia K. Smith, Leslie Brick, Divya Mehta Jan 2026

From Molecules To Minds: Integrative Multi-Omics In Psychiatry, Hossein Abbasi, Sage E. Hawn, Arash Javanbakht, Soraya Seedat, Kyle Bourassa, Sinead M. Sinnott, Antonia V. Seligowski, Sian Hemmings, Nathan A. Kimbrel, Alicia K. Smith, Leslie Brick, Divya Mehta

Psychology Faculty Publications

Psychiatric disorders are biologically complex conditions arising from interactions across genomic, epigenomic, transcriptomic, proteomic, metabolomic, and metagenomic layers. Single-omics approaches rarely capture more than a fraction of the variance in complex conditions, underscoring the importance of integrative multi-omics frameworks. This mini-review summarizes key methodologies and their application in psychiatric research, with a focus on systems-level integration of genomic risk scores, transcriptomic networks, and neuroimaging data to advance biological understanding of disorders such as depression, schizophrenia, and Alzheimer’s disease. We also outline the infrastructural requirements for effective multi-omics research, including standardized biobanking, Laboratory Information Management Systems, adherence to FAIR data principles, …