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The Influence Of Emotion On Attention : Examining The Processing Of Negative And Positive Emotion Words In The Dot Probe Task, Tina Sutton Jan 2010

The Influence Of Emotion On Attention : Examining The Processing Of Negative And Positive Emotion Words In The Dot Probe Task, Tina Sutton

Legacy Theses & Dissertations (2009 - 2024)

The influence of emotion on attention has been examined more closely in recent years using a variety of paradigms. Öhman (1993) suggested that participants more readily pay attention to negative information than neutral information. The current work was designed to expand upon these findings by examining both negative and positive emotion word processing in a non-clinical population using the dot probe task. Experiments 1a and 1b examined the supraliminal and subliminal processing of negative and positive emotion words presented in separate blocks. The results revealed that participants responded faster to the probe when it appeared in the same location as …


The Role Of The Progesterone Receptor In The Development Of The Ventromedial Nucleus And Female Sexual Behaviors, Keith L. Gonzales Jan 2010

The Role Of The Progesterone Receptor In The Development Of The Ventromedial Nucleus And Female Sexual Behaviors, Keith L. Gonzales

Legacy Theses & Dissertations (2009 - 2024)

Steroid induced gene transcription plays an important role in neural sex differences within many mammalian species. Steroid hormones actions within the developing brain have profound, permanent effects in the development of neurochemical processes and behaviors. Within the developing ventromedial nucleus of the hypothalamus (VMN), a potent transcription factor, the progesterone receptor (PR), is highly expressed within female rats. Furthermore, the regulation of PR within the developing VMN of the female rat is anatomically and developmentally specific. Typically, PR expression is highly dependent on the activity of estradiol acting at ERα. As such, circulating levels of estradiol act to induce PR …


The Static-99 And Additional Research-Based Risk Factors : A Statistical Theory To Improve Sex Offender Risk Assessment, Jeffrey C. Sandler Jan 2010

The Static-99 And Additional Research-Based Risk Factors : A Statistical Theory To Improve Sex Offender Risk Assessment, Jeffrey C. Sandler

Legacy Theses & Dissertations (2009 - 2024)

Research has indicated that adjusting Static-99 risk assessments for sexual recidivism using unguided clinical opinion reduces the accuracy of the risk assessments. While progress has been made in the last decade toward identifying which variables (both internal and external to the Static-99) are associated with the likelihood of an offender sexually recidivating, very little guidance has been given on how to consider the variables external to the Static-99 within the context of a Static-99 risk assessment. The current study proposes a statistical theory for how to incorporate certain variables into such an assessment, and provides some preliminary analyses to support …


The Interaction Of Intensity And Deviance On Auditory Event-Related Potentials: Findings Using Principal Component Analysis (Pca) Of Current Source Densities (Csds), Nathan A. Gates Jan 2010

The Interaction Of Intensity And Deviance On Auditory Event-Related Potentials: Findings Using Principal Component Analysis (Pca) Of Current Source Densities (Csds), Nathan A. Gates

Dissertations, Theses, and Capstone Projects

Mismatch negativity (MMN) studies provide insights into the brain's ability to perceive and/or detect deviations from established sensory patterns. Clinical studies investigating the loudness-dependency of auditory evoked potential (LDAEP) have shown a relationship between the intensity of an auditory stimulus and neuro-physiological or -chemical activity of the primary auditory cortex. Unfortunately, these two bodies of literature remain disjointed. The present study integrates elements of each body of literature to a) investigate the impact of varying levels of intensity deviance on N1/P2 with a standard set of intensities used in LDAEP paradigms, and b) assess the extent to which deviance-related processes …


Crossing The ‘Uncanny Valley’: Adaptation To Cartoon Faces Can Influence Perception Of Human Faces, Haiwen Chen, Richard Russell, Ken Nakayama, Margaret Livingstone Jan 2010

Crossing The ‘Uncanny Valley’: Adaptation To Cartoon Faces Can Influence Perception Of Human Faces, Haiwen Chen, Richard Russell, Ken Nakayama, Margaret Livingstone

Psychology Faculty Publications

In this study we assessed whether there is a single face space common to both human and cartoon faces by testing whether adaptation to cartoon faces can affect perception of human faces. Participants were shown Japanese animation cartoon videos containing faces with abnormally large eyes. The use of animated videos eliminated the possibility of position-dependent retinotopic adaptation (because the faces appear at many different locations) and more closely simulated naturalistic exposure. Adaptation to cartoon faces with large eyes significantly shifted preferences for human faces toward larger eyes, consistent with a common, non-retinotopic representation for both cartoon and human faces. This …


Pharmacological Reversal Of Cognitive Bias In The Chick Anxiety-Depression Continuum Model, Kristen Anne Hymel Jan 2010

Pharmacological Reversal Of Cognitive Bias In The Chick Anxiety-Depression Continuum Model, Kristen Anne Hymel

Electronic Theses and Dissertations

Cognitive bias is a phenomenon that presents in clinical populations where anxious individuals tend to adopt a more pessimistic interpretation of ambiguous aversive stimuli and depressed individuals not only tend to adopt a more pessimistic interpretation of ambiguous aversive stimuli, but also a less optimistic interpretation of ambiguous appetitive stimuli. Such biases have also been pharmacologically reversed in clinical trials. To measure cognitive bias in the chick anxiety-depression continuum model, chicks exposed to an isolation stressor of 5 min to induce an anxiety-like or 60 min to induce a depressive-like state were then tested in a straight alley maze to …


The Contribution Of Genes And Hormones To The Sexual Differention Of The Zebra Finch Song System, Jessica Bayley Thompson Jan 2010

The Contribution Of Genes And Hormones To The Sexual Differention Of The Zebra Finch Song System, Jessica Bayley Thompson

Wayne State University Theses

Recent studies in the zebra finch suggest the sexual differentiation of the song system and singing behavior may not be solely driven by steroid hormones organizing the brain, and may be genetically driven. In fact, genes and hormones might act together to produce sexual differentiation of the brain. To test this hypothesis, animals were implanted with a 1mm pellet containing 50ug of 17b-estradiol or a blank pellet on the third day post-hatching. At post-hatch day 25, the brains were collected and a double label fluorescence in situ hybridization protocol using biotin and digoxigenin-tagged mRNA probes was used to simultaneously label …


Married With Children: The Influence Of Parental Status And Gender On Ambulatory Blood Pressure, Wendy C. Birmingham, Julianne Holt-Lunstad, Adam M. Howard, Dustin Thoman Jan 2010

Married With Children: The Influence Of Parental Status And Gender On Ambulatory Blood Pressure, Wendy C. Birmingham, Julianne Holt-Lunstad, Adam M. Howard, Dustin Thoman

Faculty Publications

Background Although there is substantial evidence that social relationships and marriage may influence both psychological and physical health, little is known about the influence of children. Purpose This study examined the competing predictions regarding the directional influence of parental status and its interaction with gender—given that mothers are typically disproportionately more responsible for everyday care of children—on cardiovascular functioning. Method We examined ambulatory blood pressure (ABP) over 24 hours among 198 married males and females. Results Couples without children had significantly higher ambulatory SBP and DBP than those with children. Moreover, we found a significant interaction between parental status and …


Towards A New Measure Of Playfulness: The Capacity To Fully And Freely Engage In Play, Rebecca Cornelli Sanderson Jan 2010

Towards A New Measure Of Playfulness: The Capacity To Fully And Freely Engage In Play, Rebecca Cornelli Sanderson

Dissertations

The current study involved the development and validation of a new measure of playfulness, the Project Joy Playfulness Scale (PJPS). The PJPS was designed specifically as a brief teacher-report measure for use in the preschool classroom. Playfulness was hypothesized to include four dimensions: Active Engagement, Internal Control, Joyfulness, and Social Connection. Blending academic knowledge with on-the-ground clinical experience, the measure was collaboratively developed and then tested in two separate phases of data collection.

In the first phase of the study, two hundred and twenty-two preschool students aged three to five were rated by two classroom teachers on the alpha version …


Cannabinoid Conditioned Reward And Aversion: Behavioral And Neural Processes, Jennifer E. Murray, Rick A. Bevins Jan 2010

Cannabinoid Conditioned Reward And Aversion: Behavioral And Neural Processes, Jennifer E. Murray, Rick A. Bevins

Department of Psychology: Faculty Publications

The discovery that delta-9-tetrahydrocannabinol

(Δ9-THC) is the primary psychoactive ingredient in

marijuana prompted research that helped elucidate

the endogenous cannabinoid system of the brain.

Δ9-THC and other cannabinoid ligands with agonist

action (CP 55,940, HU210, and WIN 55,212-2)

increase firing of dopamine neurons and increase

synaptic dopamine in brain regions associated with

reward and drug addiction. Such changes in cellular

processes have prompted investigators to examine

the conditioned rewarding effects of the cannabinoid

ligands using the place conditioning task with rats and

mice. As reviewed here, these cannabinoid ligands

can condition place preferences (evidence for rewarding …


An Investigation Of Bupropion Substitution For The Interoceptive Stimulus Effects Of Nicotine, Jamie L. Wilkinson, F. Ivy Carroll, Rick A. Bevins Jan 2010

An Investigation Of Bupropion Substitution For The Interoceptive Stimulus Effects Of Nicotine, Jamie L. Wilkinson, F. Ivy Carroll, Rick A. Bevins

Department of Psychology: Faculty Publications

smoking cessation aid has not been fully elucidated, studies have found that bupropion and nicotine share behavioral and neurophysiological properties suggesting that bupropion might serve as a substitute for nicotine. In fact, bupropion prompts nicotine-appropriate responding in operant and Pavlovian drug discrimination studies with rats. A majority of the literature examining this substitution pattern has been done with an operant paradigm. The present research extended this literature by further characterizing the behavioral and neuropharmacological properties underlying the substitution for a nicotine conditioned stimulus (CS). Examination of the dose-effect function and temporal dynamics of this substitution pattern showed that bupropion (20 …


Extinction With Varenicline And Nornicotine, But Not Abt-418, Weakens Conditioned Responding Evoked By The Interoceptive Stimulus Effects Of Nicotine, Carmela M. Reichel, Jennifer E. Murray, Jessica D. Barr, Rick A. Bevins Jan 2010

Extinction With Varenicline And Nornicotine, But Not Abt-418, Weakens Conditioned Responding Evoked By The Interoceptive Stimulus Effects Of Nicotine, Carmela M. Reichel, Jennifer E. Murray, Jessica D. Barr, Rick A. Bevins

Department of Psychology: Faculty Publications

The interoceptive stimulus effects of nicotine acquire control over behavior. This observation, among others, suggests that the stimulus effects of nicotine are important in the development and tenacity of tobacco dependence. Despite this importance, there has been little research examining whether non-reinforced presentations (extinction) of a ligand that share stimulus effects of nicotine will weaken responding controlled by nicotine. Rats were trained to discriminate nicotine (0.4 mg/kg) from saline using a discriminated goal-tracking task in which nicotine signaled intermittent access to sucrose; sucrose was withheld on saline sessions. Experiment 1 examined substitution for nicotine by ABT-418, nornicotine, epibatidine, varenicline, or …


Functional Assessments In The Rodent Stroke Model, K.L. Schaar, M.M. Brenneman, S.I. Savitz Jan 2010

Functional Assessments In The Rodent Stroke Model, K.L. Schaar, M.M. Brenneman, S.I. Savitz

Psychology

Stroke is a common cause of permanent disability accompanied by devastating impairments for which there is a pressing need for effective treatment. Motor, sensory and cognitive deficits are common following stroke, yet treatment is limited. Along with histological measures, functional outcome in animal models has provided valuable insight to the biological basis and potential rehabilitation efforts of experimental stroke. Developing and using tests that have the ability to identify behavioral deficits is essential to expanding the development of translational therapies. The present aim of this paper is to review many of the current behavioral tests that assess functional outcome after …


The Relationship Between Therapeutic Alliance And Treatment Outcome In Prolonged Exposure Therapy For Adolescents With Posttraumatic Stress Disorder, Sandy Capaldi Jan 2010

The Relationship Between Therapeutic Alliance And Treatment Outcome In Prolonged Exposure Therapy For Adolescents With Posttraumatic Stress Disorder, Sandy Capaldi

PCOM Psychology Dissertations

The present study focused on the therapeutic alliance in Prolonged Exposure Therapy for adolescent girls with sexual abuse-related Posttraumatic Stress Disorder (PTSD). Two major questions were investigated. First, how does the therapeutic alliance act as a moderating variable between outcome and three predictor variables (homework compliance, habituation to the trauma memory, and number of sessions completed)? Second, how is the relationship between outcome and these same variables affected by the strength of the therapeutic alliance? The data used in this study were taken from an existing database of information on 40 sexually abused adolescent girls with PTSD (mean age = …


Integrity Of Neuropsychological Processes In Children With Attention-Deficit/Hyperactivity Disorder And Comorbid Conditions, Julie N. Henzel Jan 2010

Integrity Of Neuropsychological Processes In Children With Attention-Deficit/Hyperactivity Disorder And Comorbid Conditions, Julie N. Henzel

PCOM Psychology Dissertations

This study investigated the neuropsychological and behavioral profiles seen in children diagnosed with ADHD inattentive type (IA), inattentive type plus an internalizing disorder (IA + INT), combined type (CT), and combined type plus an externalizing disorder (CT + EXT). Subjects were 63 unmedicated children aged 6 to 16 who had been assessed with the Wechsler Intelligence Scale for Children–Fourth Edition (WISC–IV), Conners’ Continuous Performance Test-Second Edition (CPT–II), and the Child Behavior Checklist (CBCL). Group differences were found for the WISC–IV Digits Backward subtest (IA + INT IA and IA + INT), and externalizing behavior scales on the CBCL and TRF …


Does Chronic Stress Accelerate Late-Aging Cognitive Decline In Memory And Executive Functioning?, Diane Robinson Jan 2010

Does Chronic Stress Accelerate Late-Aging Cognitive Decline In Memory And Executive Functioning?, Diane Robinson

Electronic Theses and Dissertations

Few studies exist examining the relationship between self-reported stress and cognitive function in healthy nonpsychiatric older adults, and even less studies have examined whether high levels of self-reported stress accelerate the cognitive decline found in normal late-aging populations. A group of older nonpsychiatric adults, ages 54 years and above, were asked to complete three measures assessing their self-perceived stress over the past month, past year, and their lifetime. Sixty-one adults between the ages of 54 and 88 (52% female) participated in a second phase in which neuropsychological tasks were administered to assess three cognitive domains; memory, learning, and executive functioning. …


Ageist Perceptions In Personnel Selection Decisions: A Prejudice-Reduction Intervention, Justin Marcus Jan 2010

Ageist Perceptions In Personnel Selection Decisions: A Prejudice-Reduction Intervention, Justin Marcus

Electronic Theses and Dissertations

The purpose of the current study was to examine whether older job applicants are discriminated against relative to younger job applicants when changing careers, and to investigate whether an intervention designed to reduce stereotyping and prejudice could alleviate such unfair discrimination, if it was found. A between-subjects laboratory experiment with three factors was conducted, including age (young vs. old job applicant), career-transition type (within- vs. between-career transition), and a dual-identity based recategorization intervention (control vs. intervention), totaling 8 experimental conditions. Data were collected and analyzed from 157 undergraduate student participants. Participants were informed that they would be evaluating the viability …


Phenomenology Of Embodied Dreamwork With Puerto Rican Women: A Dissertation, Lourdes F. Brache-Tabar Jan 2010

Phenomenology Of Embodied Dreamwork With Puerto Rican Women: A Dissertation, Lourdes F. Brache-Tabar

Expressive Therapies Dissertations

The author investigated the experience of embodied dreamwork. Participants were eight Puerto Rican women who were chronically ill, of low socioeconomic status, who lived in Boston. The data were analyzed using transcendental phenomenology. Each participant engaged in one embodied dreamwork–unstructured interview session lasting approximately 1.5 hours. In addition, each participant drew a picture of how she felt after the dreamwork interview. This snowball, purposive sample gave detailed information about how they experienced embodied dreamwork. The participants’ statements were grouped into themes: (a) sense of place—environment, surroundings, spatiality; (b) the players—self, others; (c) plot; (d) in the sea of emotions—naming affective …


Female And Male Psychologists In Academic Administration: Resource Control And Perceived Influence, Jennifer Schenk Jan 2010

Female And Male Psychologists In Academic Administration: Resource Control And Perceived Influence, Jennifer Schenk

Doctor of Psychology (PsyD)

This study examined male and female psychologists in academic administrative positions with regard to their perceptions of their own power and their actual power within the administrative hierarchies in which they work. In the past, researchers have compared women and men in academic administrative positions with regard to parity of numbers, salaries, number of publications and citations, types of institutions where they work and, the job titles they hold. These indices had suggested that women administrators had less prestige, control fewer resources, and a more limited scope of job responsibilities than did men. However, there had been no comparison of …


The Effects Of Communication Disorders On Social Development, Heather M. Back Jan 2010

The Effects Of Communication Disorders On Social Development, Heather M. Back

CMC Senior Theses

This paper explores literature on the effects of communication disorders on the social development of children. The paper discusses such topics as the effects of communication disorders on personality development, the ability to make friends and resolve conflict with peers, and academic success. It also discusses the influences of multiculturalism and bilingualism on the diagnosis of communication disorders and reflects on the importance of awareness of cultural differences in communication style to avoid a misdiagnosis. Research shows that without intervention and treatment communication disorders can have irreversible detrimental effects on a child’s ability to develop effect social-communication, to make friends, …


An Examination Of Challenging Behaviors In Autistic Disorder Versus Pervasive Developmental Disorder Not Otherwise Specified: Significant Differences And Gender Effects, Alison M. Kozlowski Jan 2010

An Examination Of Challenging Behaviors In Autistic Disorder Versus Pervasive Developmental Disorder Not Otherwise Specified: Significant Differences And Gender Effects, Alison M. Kozlowski

LSU Master's Theses

Children with Autism Spectrum Disorders (ASDs) are well-known for engagement in challenging behaviors. Unfortunately, due to its absence as a criterion for diagnosis in the DSM-IV-TR, little attention has been paid to the endorsement rates of such behaviors. However, a recently developed measure to assist in the diagnosis of infants and toddlers with autism and PDD-NOS – the Baby and Infant Screen for Children with aUtIsm Traits (BISCUIT) – has included a section designated for just this reason. This study used the BISCUIT to assess for significant differences in the endorsement rates of challenging behaviors between infants and toddlers with …


Do The Stimulant Medications Improve Neuropsychological Performance Of College Students With Adhd?, Chunqiao Luo Jan 2010

Do The Stimulant Medications Improve Neuropsychological Performance Of College Students With Adhd?, Chunqiao Luo

LSU Master's Theses

Attention Deficit/Hyperactivity Disorder (ADHD) is a prevalent disorder estimated to affect 5% to 10% of school-aged children and approximately 4% of adults worldwide. The defining symptoms are hyperactivity, impulsivity and inattention, which are all acutely reduced by the stimulant medications, methylphenidate and amphetamine. Nevertheless, in spite of robust short-term efficacy, long-term follow-up studies fail to show drug effects on academic achievement of ADHD students. Because recent research indicates that the medications also do not normalize performance of ADHD patients on some neuropsychological tests, we thought this might shed some light on the causes of ADHD students’ academic underachievement. There is …


(2010) Philosophical Dialogue With Children: Essays On Theory And Practice, David Kennedy Jan 2010

(2010) Philosophical Dialogue With Children: Essays On Theory And Practice, David Kennedy

Collected Papers of David Kennedy

David Kennedy is the foremost expert of children’s philosophical experience and practice writing today. One of the factors that makes him so will be apparent to readers of this collection of essays: the insistent probing and the astonishing range of his scholarship, which encompasses philosophy of childhood, philosophy of education, developmental psychology, cultural studies, critical theory, philosophy of subjectivity, chaos and systems theory, epistemology, and metaphilosophy. The other factor, only hinted at in this book, is the thousands of hours that Kennedy has clocked on the rugs and in the small chairs of schools, pre-schools, churches and other children’s spaces …


Children's Tolerance Of Word-Form Variation, Paul Reeves Breuning Jan 2010

Children's Tolerance Of Word-Form Variation, Paul Reeves Breuning

Dissertations, Theses, and Capstone Projects

This study compared children's (N=96, mean age 4;1, range 2;8-5;3) and adults' (N=96, mean age 21 years) tolerance of word-onset modifications (e.g., wabbit and warabbit) and pseudo affixes (e.g., kocat and catko) in a label extension task. Trials comprised an introductory phase where children saw a picture of an animal and were told its name, and a test phase where they were shown the same picture along with one of a different animal. For `similar-name' trials, participants heard a word-form modification of the previously introduced name (e.g., introduced to a dib, they were asked, `which animal is a wib?'). For …


School Psychologists' Knowledge Of Tourette Syndrome Characteristics And Awareness Of Appropriate Interventions, Jesse Usher Glassman Jan 2010

School Psychologists' Knowledge Of Tourette Syndrome Characteristics And Awareness Of Appropriate Interventions, Jesse Usher Glassman

PCOM Psychology Dissertations

Tourette Syndrome (TS) is a neurodevelopmental disorder consisting of multiple involuntary motor tics and one or more vocal tics. The duration of the disorder is at least one year and not more than three consecutive tic-free months (APA, 2000). The tics associated with TS are frequently more severe than other tic disorders on the spectrum. There are varying degrees of severity of TS disorder, requiring maximum to no treatment. Children and adolescents diagnosed and who are showing signs of TS are referred for school evaluations in order to identify various learning difficulties and /or emotional issues which are often associated …


Addressing Negative Effects Of Psychotherapy During The Informed Consent Process : The Licensed Psychologists' Perspectives , Neshe Sarkozy Jan 2010

Addressing Negative Effects Of Psychotherapy During The Informed Consent Process : The Licensed Psychologists' Perspectives , Neshe Sarkozy

PCOM Psychology Dissertations

This survey study investigated attitudes and practices of 161 licensed psychologists from a nationwide sample, relative to addressing negative effects of psychotherapy during the informed consent process. Results revealed discrepancies in attitudes toward risk of negative treatment effects in psychotherapy and in addressing risk during the process of informed consent. Information obtained from this study may contribute to research in the area of clinical implementation of the American Psychological Association’s Code of Ethics. Implications for clinical practice are discussed. Limitations of the study and directions for future research are also addressed.


Meal Parameters And Vagal Gastrointestinal Afferents In Mice That Experienced Early Postnatal Overnutrition, Jessica Biddinger, Edward A. Fox Jan 2010

Meal Parameters And Vagal Gastrointestinal Afferents In Mice That Experienced Early Postnatal Overnutrition, Jessica Biddinger, Edward A. Fox

Department of Psychological Sciences Faculty Publications

Early postnatal overnutrition disrupts satiety without altering vagal gastrointestinal afferents. PHYSIOL BEHAV 00(0) 000-000, 2010. Early postnatal overnutrition results in a predisposition to develop obesity due in part to hypothalamic and sympathetic dysfunction. Potential involvement of another major regulatory system component - the vagus nerve - has not been examined. Moreover, feeding disturbances have rarely been investigated prior to development of obesity when confounds due to obesity are minimized. To examine these issues, litters were culled on the day of birth to create small litters (SL; overnutrition), or normal-size litters (NL; normal nutrition). Body weight, fat pad weight, meal patterns, …


Reflexivity In Pigeons, Mary M. Sweeney, Peter J. Urcuioli Jan 2010

Reflexivity In Pigeons, Mary M. Sweeney, Peter J. Urcuioli

Department of Psychological Sciences Faculty Publications

A recent theory of pigeons’ equivalence-class formation (Urcuioli, 2008) predicts that reflexivity, an untrained ability to match a stimulus to itself, should be observed after training on two “mirror-image” symbolic successive matching tasks plus identity successive matching using some of the symbolic matching stimuli. One group of pigeons was trained in this fashion; a second group was trained similarly but with successive oddity (rather than identity). Subsequently, comparison-response rates on novel matching versus mismatching sequences with the remaining symbolic matching stimuli were measured on non-reinforced probe trials. Higher rates were observed on matching than on mismatching probes in the former …


Associative Symmetry And Stimulus-Class Formation By Pigeons: The Role Of Non-Reinforced Baseline Relations, Peter J. Urcuioli Jan 2010

Associative Symmetry And Stimulus-Class Formation By Pigeons: The Role Of Non-Reinforced Baseline Relations, Peter J. Urcuioli

Department of Psychological Sciences Faculty Publications

Two experiments tested the assumption of Urcuioli’s (2008) theory of pigeons’ equivalence-class formation that consistent non-reinforcement of certain stimulus combinations in successive matching juxtaposed with consistent reinforcement of other combinations generates stimulus classes containing the elements of the reinforced combinations. In Experiment 1, pigeons were concurrently trained on symbolic (AB) and two identity (AA and BB) successive tasks in which half of all identity trials ended in non-reinforcement but all AB trials were reinforced, contingent upon either responding or not-responding to the comparisons. Subsequent symmetry (BA) probe trials showed evidence of symmetry in one of four pigeons. In Experiment 2, …


Mice Deficient In Brain-Derived Neurotrophic Factor Have Altered Development Of Gastric Vagal Sensory Innervation, Michelle C. Murphy, Edward A. Fox Jan 2010

Mice Deficient In Brain-Derived Neurotrophic Factor Have Altered Development Of Gastric Vagal Sensory Innervation, Michelle C. Murphy, Edward A. Fox

Department of Psychological Sciences Faculty Publications

Vagal sensory neurons are dependent on neurotrophins to survive programmed cell death during development. Here, the contribution of brain-derived neurotrophic factor (BDNF) to the survival of gastric vagal sensory afferents was investigated. Also, based on BDNF roles in other sensory systems, its effects on axon guidance and mechanoreceptor differentiation were examined. Postmortem anterograde tracing with 1, 1’-dioctadecyl-3,3,3’,3’-tetramethylindocarbocyanine perchlorate (DiI) was used to selectively label vagal projections to the stomach on postnatal day (P)0, 3, 4, and 6 in wild types and heterozygous or homozygous BDNF mutants. Sampling sites distributed throughout the ventral stomach wall were scanned with a confocal microscope …