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Distinct Neuropsychological Profile And Associated Neurochemical Changes In Individuals With Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes (Melas), Emily B. Leaffer Sep 2018

Distinct Neuropsychological Profile And Associated Neurochemical Changes In Individuals With Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes (Melas), Emily B. Leaffer

Dissertations, Theses, and Capstone Projects

Background: Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS) is a maternally inherited progressive multisystemic disorder. Occurrence of seizure and/or stroke-like episode, as well as classic biomarkers (i.e., cerebral lactic acidosis, depleted N-acetylaspartate (NAA)), have been linked to neuropsychological deficit and trigger the developmental cascade of neurodegeneration affecting posterior prior to anterior brain regions. While a pattern of global deterioration has been reported, systematic examination in a large MELAS cohort has not been conducted.

Objective: First, we examined verbal and visual memory function and its relationship to brain metabolites (lactate, NAA) in individuals with MELAS. Second, we hypothesized that MELAS …


Parents Frame Childhood For The World To See In Digital Media Postings, Aysenur Benevento Sep 2018

Parents Frame Childhood For The World To See In Digital Media Postings, Aysenur Benevento

Dissertations, Theses, and Capstone Projects

With the wellbeing of children being at the center of contemporary media discourse (Livingstone & Bovill, 2013), developmental studies are ever more challenged to understand both children’s and adults’ behavior in online spaces. Parents and children are involved in the human development process in complementary ways (Johansson, 2010; Uprichards, 2008) while using media platforms. As the development and use of innovative media technology are accelerating at a fast pace, theory and methods for analyzing uses of digital media for human development have lagged behind. This study examines adults’ postings of photos of their children on social media and offers a …


Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones Sep 2018

Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones

Dissertations, Theses, and Capstone Projects

The study of how the brain acquires fearful memories has attracted considerable experimental attention, due in part to the promise of discovering novel therapeutic approaches for psychiatric disorders that are characterized by unusually strong and persistent traumatic memories. In recent years, extensive research has focused on studying the neural and molecular mechanisms by which fear memories are acquired, stored, and retrieved in the brain. Once acquired, fear memories may be attenuated using one of 2 procedures: 1) fear extinction, which involves repeated presentation of the fear-arousing stimulus in the absence of an aversive consequence, or 2) interference with the reconsolidation …


The Interpersonal Effect Of Guilt Expressions On Cooperation: The Role Of Social Perceptions, Nadhilla Velda Melia Sep 2018

The Interpersonal Effect Of Guilt Expressions On Cooperation: The Role Of Social Perceptions, Nadhilla Velda Melia

Dissertations and Theses Collection (Open Access)

People can make inferences about an individual based on his or her emotional expressions, and these inferences can affect their subsequent behavior. I conducted two experiments to investigate the social perceptions associated with a transgressor’s guilt expression after he or she commits a social transgression, and how these would subsequently affect the cooperative behavior of the victims of the transgression. Study 1 demonstrated that there was an indirect effect of a transgressor’s guilt expression on a victim’s cooperation via the victim’s perception of the transgressor’s benevolence, but not via the victim’s perception of the transgressor’s perspective-taking. Study 2 showed partial …


Bias-Motivated Homicides: Toward A New Typology, Lindsey Sank Davis Sep 2018

Bias-Motivated Homicides: Toward A New Typology, Lindsey Sank Davis

Dissertations, Theses, and Capstone Projects

Despite significant progress towards equal protection under the law for women, LGBT individuals, and people of color in the United States, hate crime remains a pervasive problem, and rates appear to have increased in recent years. Bias-motivated homicide – arguably the most serious form of hate crime – is statistically rare but may have far-reaching consequences for marginalized communities. Data from the Uniform Crime Reports and the National Crime Victimization Survey have suggested that, on average, fewer than 10 bias-motivated homicides occur in the United States per year; however, data from open sources indicate that the rate of bias-motivated homicide …


Detecting Cognitive, Functional And Behavioral Response To Donepezil In Alzheimer’S Disease: The Role Of Attention Tasks, Clara Vila-Castelar Sep 2018

Detecting Cognitive, Functional And Behavioral Response To Donepezil In Alzheimer’S Disease: The Role Of Attention Tasks, Clara Vila-Castelar

Dissertations, Theses, and Capstone Projects

Introduction: Cholinesterase Inhibitors (ChEIs) used in Alzheimer’s Disease (AD) have modest effects, heterogeneous treatment response, and it has been difficult to detect treatment response. The standard research and clinical outcome measure, the Alzheimer’s Disease Assessment Scale-Cognitive subscale (ADAS-Cog) aggregates multiple cognitive domains, and has limited sensitivity. We propose that because acetylcholine is directly linked to the cognitive domain of attention, and ChEIs increase available acetylcholine, measures of attention under high-load conditions could predict long-term cognitive, functional and behavioral response, and thus, unlike global measures, could be sensitive to treatment efficacy.

Method: We conducted a longitudinal, open label donepezil trial …


Can Mindfulness Training Reduce Stress Reactivity In First-Year College Students?, Liat Zitron Sep 2018

Can Mindfulness Training Reduce Stress Reactivity In First-Year College Students?, Liat Zitron

Dissertations, Theses, and Capstone Projects

ABSTRACT

Can Mindfulness Training Reduce Stress-Reactivity in First-Year College Students?

By

Liat Zitron

Advisor: Yu Gao, PhD

The positive effects of mindfulness-based practices on stress reactivity have been gaining steady attention in recent years. Yet, the effects of mindfulness training on stress responses via the autonomic nervous system (ANS) functioning, and in particular, changes in cardiovascular activity, have rarely been researched. The polyvagal theory (Porges, 1995) offers a theoretical framework in which the roles of the subdivisions of the ANS in regulating emotion and behaviors are delineated, and closely connected to the concept of heart rate variability (HRV) and its …


The Effects Of A Voice Treatment On Facial Emotional Expression In Parkinson's Disease: Expressivity, Experience, And Gender, Elizabeth M. Murray Sep 2018

The Effects Of A Voice Treatment On Facial Emotional Expression In Parkinson's Disease: Expressivity, Experience, And Gender, Elizabeth M. Murray

Dissertations, Theses, and Capstone Projects

Individuals with Parkinson’s disease (PD) suffer from decreased ability to express emotion through facial expression, in what has been termed “masked facies” or hypomimia. Facial emotional expression is necessary for the accurate communication of needs, to obtain or maintain empathy from care-givers, and to be perceived by others in a way that matches the way that one feels. The current study provides a review of the deficits seen in Parkinson’s disease, an overview of the neurobehavioral disparity of spontaneous versus posed facial expression of emotion, and factors that influence the perception of emotion, such as gender and clinical variables. The …


Sex Differences In Rhesus Monkeys’ Digit Ratio (2d:4d Ratio) And Its Association With Maternal Social Dominance Rank, Alexander Baxter, Elizabeth K. Wood, Parker Jarman, Ashley N. Cameron, John P. Capitanio, James Dee Higley Sep 2018

Sex Differences In Rhesus Monkeys’ Digit Ratio (2d:4d Ratio) And Its Association With Maternal Social Dominance Rank, Alexander Baxter, Elizabeth K. Wood, Parker Jarman, Ashley N. Cameron, John P. Capitanio, James Dee Higley

Faculty Publications

Prenatal androgen exposure (PAE) plays a pivotal role in masculinizing the developing body and brain, and extreme exposure may contribute to autism, anxiety disorder and schizophrenia. One commonly used biomarker for PAE is the pointer-to-ring-finger digit length (2D:4D) ratio. Although this biomarker is widely used in human studies, relatively few studies have investigated 2D:4D ratio in nonhuman primates, particularly rhesus macaques (Macaca mulatta), one of the most commonly used animals in biomedical research. Thus far, data suggest that sexual dimorphism in 2D:4D ratio may be in the opposite direction in some monkey species, when compared to the pattern …


Advancing Social Connection As A Public Health Priority In The United States, Julianne Holt-Lunstad, Theodore Robles, David A. Sbarra Sep 2018

Advancing Social Connection As A Public Health Priority In The United States, Julianne Holt-Lunstad, Theodore Robles, David A. Sbarra

Faculty Publications

A robust body of scientific evidence indicates that being embedded in high-quality close relationships and feeling socially connected to the people in your life is associated with decreased risk for all-cause mortality as well as a range of disease morbidities. Despite mounting evidence that the magnitude of these associations is comparable to many leading health determinants (that receive significant public health resources), government agencies, healthcare providers and associations, and public/private healthcare funders are slow to recognize human social relationships as either a health determinant or health risk marker in a manner that is comparable to other public health priorities. This …


The (B)Link Between Amotivation And Dopamine In Psychosis: What Phasic Eye Blink Rate Reveals, Jessica Elaina Mcgovern Aug 2018

The (B)Link Between Amotivation And Dopamine In Psychosis: What Phasic Eye Blink Rate Reveals, Jessica Elaina Mcgovern

LSU Doctoral Dissertations

Motivation deficits (i.e., avolition or amotivation) are a cardinal feature of schizophrenia spectrum disorders (SSDs) and are linked to worse functional outcomes. Accumulating evidence implicates underactive dopamine responses in reward areas of the brain (e.g., striatum) in the etiology of amotivation. Phasic dopamine firing in the striatum purportedly has a role in increasing the perceived value of a potential reward that, in effect, helps “push” the organism toward initiating and persisting in the action to pursue rewards. Previous research has suggested that eye blink rate (EBR) may be a reliable and valid index of striatal dopamine. Amotivation (clinician-rated and self-reported) …


Global Media Wars: The Ironic Prescience Of George Orwell, Ibpp Editor Aug 2018

Global Media Wars: The Ironic Prescience Of George Orwell, Ibpp Editor

International Bulletin of Political Psychology

This article describes similar psychologies among people who intend to tell the truth and those who intend to lie. It posits the writings of George Orwell on political communication as relevant today as back in the 1940s.


Biological Stress Response And Cognitive Vulnerability To Depression In Adolescence, Bridget M. Brush Aug 2018

Biological Stress Response And Cognitive Vulnerability To Depression In Adolescence, Bridget M. Brush

College of Science and Health Theses and Dissertations

Depression is the leading cause of worldwide disability. Rates of Major Depressive Disorder (MDD) increase exponentially over the adolescent transition, suggesting adolescence represents a key period of risk for the onset of depression. Previous research has associated both biological stress response and cognitive vulnerability with symptoms of depression; however, there is little research examining the joint effects of these two risk factors and symptoms of depression, especially during adolescence. The present study examined the association between symptoms of depression and two established risk factors for depression: cognitive vulnerability, as measured by negative cognitive style, and biological stress response, as measured …


Teaching Caregivers To Integrate Four Play-Based Instructional Strategies Without Decrements In Child Play And Preference, Maegan Pisman Aug 2018

Teaching Caregivers To Integrate Four Play-Based Instructional Strategies Without Decrements In Child Play And Preference, Maegan Pisman

Theses & Dissertations

Young children diagnosed with autism spectrum disorder (ASD) often require systematic teaching to learn new skills, and caregivers can teach their children by embedding learning opportunities in a play-based context. However, researchers have not evaluated procedures to train caregivers to implement a combination of strategies designed to establish rapport and early language skills while maintaining play as a preferred context. We recruited two caregiver-child dyads composed of two mothers and their sons (3 and 4 years old). We used a multiple-probe design across strategies to demonstrate the efficacy of behavioral skills training on the mothers’ integration of parallel play, child-directed …


The Truthiness Effect: The Influence Of Nonprobative Photos On Truth Judgments, Laura N. Mangus Aug 2018

The Truthiness Effect: The Influence Of Nonprobative Photos On Truth Judgments, Laura N. Mangus

Seton Hall University Dissertations and Theses (ETDs)

Truthiness is used to describe a person’s instinctive and rapid judgment about the truth of a claim, with no regard to logic or fact. Recent research has shown that a photo can influence a person to believe a claim is true, even if the photo used is non-probative. This effect is hypothesized to occur because photographs make claims easier to process while also enabling one to retrieve related thoughts and images to mind, which can then be mistaken for familiarity and truth (Newman, Garry, Bernstein, Kantner, & Lindsay, 2012). Cognitive load and response time manipulation were factors that had not …


Biological And Behavioral Mechanisms Underlying Childhood Physical Abuse And Age-Related Disease: Borderline Personality Pathology And Inflammation, Christina Rae Di Iorio Aug 2018

Biological And Behavioral Mechanisms Underlying Childhood Physical Abuse And Age-Related Disease: Borderline Personality Pathology And Inflammation, Christina Rae Di Iorio

Arts & Sciences Graduate Student Theses and Dissertations

Background: The frequent comorbidity of psychiatric and physical health conditions may be partially attributable to early life stress-related changes in inflammatory signaling and behavior (e.g., borderline personality pathology, health behaviors) that reciprocally maintain and enhance their effects on overall health.Methods: Using data from older adults (n=1,630) who participated in the ongoing longitudinal St Louis Personality and Aging Network (SPAN) study, we examined associations between childhood physical abuse, borderline pathology, inflammation markers (i.e., interleukin 6, c-reactive protein), health behaviors, and physical health. Morning fasting serum IL-6 and CRP were assayed from a subset of participants (n=791). Borderline pathology factor scores were …


The Impact Of Mother And Father Stress On Child Externalizing Behaviors, Allison Mccobin Aug 2018

The Impact Of Mother And Father Stress On Child Externalizing Behaviors, Allison Mccobin

Electronic Theses and Dissertations

The impact of parental stress on child behavioral problems has often been examined through research. A large majority of research indicates a strong correlation between parenting stress and an increase in child behavioral difficulties. However, most studies have focused only on the impact that one parent’s stress has on the child’s behavior, rather than both or comparing the two. Using two separate cross-lagged structural equation models, data from the Fragile Families Child and Wellbeing Study (N = 1010) were analyzed to examine the differences between mother and father parenting stress on child externalizing behavior problems over time (ages three and …


Wellness And Karate, Cristina Kumpf Aug 2018

Wellness And Karate, Cristina Kumpf

Electronic Theses and Dissertations

The promotion of wellness is an integral part of the counseling field and is considered to be a central focus to the counseling process (Barden, Conley, & Young, 2015; Myers, 1992). The counseling profession adopted the concept of wellness because it harmonizes with many of the founding principles of the ACA and is seen as a process of questing toward optimal health and well-being in body, mind, and spirit (Barden, Conley, & Young, 2015; Myers, 1992; Myers, Sweeney, & Witmer, 2000). Additionally, ACA Code of Ethics (2014) state that counselors “engage in self-care activities to maintain and promote their own …


The Zombie Apocalypse Has Already Happened: Queering Subjectivity In Zombie Film, Jessica Dunn Aug 2018

The Zombie Apocalypse Has Already Happened: Queering Subjectivity In Zombie Film, Jessica Dunn

Electronic Theses and Dissertations

This dissertation traces the encounter between psychology as a human science and the viral zombie film genre using the collaborative works of Deleuze and Guattari in conjunction with the queer anti-humanist theories of Colebrook and Halberstam. I interwove thematic (i.e. plot, dialogue, character development) and cinematographic (i.e. shot composition, editing, lighting, musical score) analyses of fourteen viral zombie films with theoretical arguments regarding the deterritorialization of the human subject and its relevance to psychology as a human science. The films were selected from the plethora of viral zombie films released after the turn of the 21st century. The selection was …


The Effects Of Power And Religiously Motivated Ingroup Preference On Social Affiliation, Hernan Escobar Aug 2018

The Effects Of Power And Religiously Motivated Ingroup Preference On Social Affiliation, Hernan Escobar

Electronic Theses and Dissertations

Human beings are fundamentally social animals motivated by a need to establish and maintain close social relationships. The creation of these relationships inevitably leads to the creation of groups, along with a desire for power as a method of determining how resources are to be allocated within these groups. Most groups are characterized by individuals who belong to the ingroup and those who are relegated to an outgroup, and one powerful motivator of ingroup favoritism is religious affiliation. Although research has shown that feelings of low power increase the drive to socially affiliate, research has not yet explored how religious …


Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen Aug 2018

Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen

The Goose

Review of Daniel Coleman's Yardwork: A Biography of an Urban Place.


Spiritual Struggles Among Atheists: Links To Psychological Distress And Well-Being, Aaron E. Sedlar, Nick Stauner, Kenneth A. Pargament, Julie J. Exline, Joshua B. Grubbs, David F. Bradley Aug 2018

Spiritual Struggles Among Atheists: Links To Psychological Distress And Well-Being, Aaron E. Sedlar, Nick Stauner, Kenneth A. Pargament, Julie J. Exline, Joshua B. Grubbs, David F. Bradley

Psychology Faculty Publications

Religious and spiritual struggles (R/S struggles)—tension or conflicts regarding religious or spiritual matters—have been robustly linked to greater psychological distress and lower well-being. Most research in this area has relied on samples consisting predominantly of participants who believe in god(s). Limited research has examined R/S struggles among atheists, generally conflating them with agnostics and other nontheists. This study investigated the prevalence of R/S struggles among atheists and compared atheists to theists in two samples (3978 undergraduates, 1048 Internet workers). Results of a multilevel model showed that atheists experience less demonic, doubt, divine, moral, and overall R/S struggles than theists, but …


Prompts To Increase Physical Activity At Points-Of-Choice Between Stairs And Escalators: What About Escalator Climbers?, John Belletierre, Ben Nguyen, Sandy Liles, Vincent Berardi, Marc A. Adams, Paddy Dempsey, Yael Benporat, Jacqueline Kerr, Andrea Z. Lacroix, Melbourne Hovell Aug 2018

Prompts To Increase Physical Activity At Points-Of-Choice Between Stairs And Escalators: What About Escalator Climbers?, John Belletierre, Ben Nguyen, Sandy Liles, Vincent Berardi, Marc A. Adams, Paddy Dempsey, Yael Benporat, Jacqueline Kerr, Andrea Z. Lacroix, Melbourne Hovell

Psychology Faculty Articles and Research

Since 1980, many studies have evaluated whether stair-use prompts increased physical activity by quantifying changes in stair use. To more completely evaluate changes in physical activity, this study addressed the often-overlooked assessment of climbing up escalators by evaluating the degree to which stair-use sign prompts increased active ascent—defined as stair use or escalator climbing. Over 5 months, at an airport stairs/escalator point of choice, we video-recorded passersby (N = 13,544) who ascended either stairs or escalators, on 10 days with signs and 10 days without signs. Ascenders using the stairs, standing on the escalator, and climbing the escalator were …


Parental Stress, Anxiety, And Depression And Child Emotional Intelligence In Children With 22q11.2 Deletion Syndrome, Megan A. Goldfarb Aug 2018

Parental Stress, Anxiety, And Depression And Child Emotional Intelligence In Children With 22q11.2 Deletion Syndrome, Megan A. Goldfarb

LSU New Orleans Theses and Dissertations

Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) have serious medical, psychological, and behavioral symptoms that are stressful to their parents. Higher general intelligence quotients (IQ) and emotional intelligence (EI) in children could allay parental stress. Self-reported stress, anxiety, and depression were measured in parents of children with 22q11.2DS (n=42) and a healthy control group (n=20) in relation to children’s IQ and EI. Children with 22q1.2DS had lower IQ and EI scores. Parental groups did not differ in their reported stress, anxiety, or depression. Children’s IQ and EI levels did not relate to parental measures of affect even in the 22q11.2DS …


Visual Pleasure And Racial Ambiguity, Ruth M. Owens Md Aug 2018

Visual Pleasure And Racial Ambiguity, Ruth M. Owens Md

LSU New Orleans Theses and Dissertations

I struggle to present work that reflects a psychological expressivity which at the same time conveys intellectual concepts that are of concern to me. It seems that the fluidity of an image can communicate a certain pathos, and correspond to the fluid nature of one’s identity. Drippy paint, distorted bodies, and vertiginous video clips can give an indication about what a body feels like from within. Depictions of these bodily feelings help to communicate ideas about what it means to be alive in general, and a mixed race woman, in particular.


A Longitudinal Examination Of The Association Between Contextual Stress, Parenting, And School Readiness, Jessica M. Grande Aug 2018

A Longitudinal Examination Of The Association Between Contextual Stress, Parenting, And School Readiness, Jessica M. Grande

LSU New Orleans Theses and Dissertations

Contextual stress has been associated with poor school readiness skills during early childhood. This study evaluated mechanisms by which parent’s exposure to poverty-related contextual stressors influence the acquisition of school readiness skills from child age 2 to 4 among 167 parent-child dyads. Parent report of contextual stress and observational measures of parenting quality were collected during the children’s 2-year-old assessment. Teacher reports and children’s scores on school readiness tasks were collected during the 4-year-old assessment. Two approaches were used to understand the process by which contextual stressors influences school readiness; the accumulation of stressors approach and the constellations of stressors …


Bubble Stream Production By Belugas (Delphinapterus Leucas), Megan Slack Aug 2018

Bubble Stream Production By Belugas (Delphinapterus Leucas), Megan Slack

Theses

Bubble stream production in belugas has been poorly characterized and its function is not well understood. I examined behavioral states when producing bubble streams (“bubbling”), and when bubbling calls, to determine whether bubbling was significantly associated with a particular call category or behavioral state. Using 19 hours of video and audio recordings collected over a two-day period, I quantified bubble streams of a 4-month old calf and an unrelated adult female housed together. Based on the overall activity budgets and pool of vocalizations for both animals, I calculated the expected counts of bubble streams with and without vocalizations, assuming that …


Sexual Assault And Health: Understanding The Interplay Of Trauma-Related Appraisals And Physical Health Outcomes, Kerry Lyn Gagnon Aug 2018

Sexual Assault And Health: Understanding The Interplay Of Trauma-Related Appraisals And Physical Health Outcomes, Kerry Lyn Gagnon

Electronic Theses and Dissertations

Women who have been sexually assaulted are at risk for negative mental and physical health outcomes; however, limited research has tested how psychological responses to sexual assault may influence physical health. The present study tested a longitudinal model examining the association between posttrauma appraisals and physical health problems. Drawn from a larger study, the sample included 156 ethnically diverse women who had been sexually assaulted within the last year. The study used cross-lagged panel models to test for reciprocal relationships between posttrauma appraisals and physical health problems over time. A secondary aim of the study was to test whether other …


Understanding The Relationship Between Positive Affect And Cortisol In Lung Cancer Patients., Lauren Ann Zimmaro Aug 2018

Understanding The Relationship Between Positive Affect And Cortisol In Lung Cancer Patients., Lauren Ann Zimmaro

Electronic Theses and Dissertations

Positive psychobiological processes within lung cancer patients are drastically understudied. This dissertation explores the nature of positive affect (PA) and potential associations with diurnal cortisol among lung cancer patients, given the prognostic significance of diurnal cortisol rhythms. Theoretical underpinnings and current literature involving PA, cancer, and diurnal cortisol are first reviewed. An original integrated model of PA and cortisol among cancer patients is then presented, from which the proposed dissertation study and analyses are derived. Sixty-one non-small cell lung cancer patients provided self-report assessment of mood (PANAS PA and NA subscales, CES-D PA subscale), medical and demographic characteristics, and 10-day …


Contextual Factors In The Identity Development Of Native American And Latinx Undergraduates In Stem Fields, Angela Marie Enno Aug 2018

Contextual Factors In The Identity Development Of Native American And Latinx Undergraduates In Stem Fields, Angela Marie Enno

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study includes two papers that aimed to provide insights into the experiences of high-achieving Latinx and Native American college students studying science. We wanted to better understand factors that influence these students’ ability to develop a sense of identity that weaves together their hoped-for careers as scientists as well as their cultural identities. We looked at how they feel about working with mentors in science fields who were like them in a variety of ways. We found that many students (especially those with a stronger sense of cultural identity) valued working with mentors who were similar to them in …