Digital Commons Network^™

Escitalopram Treatment To The Hiv-1 Transgenic Rat: Spine Dynamics, Telomere Quantification And Neurogenesis, Adam Ray Denton

Theses and Dissertations

HIV is a serious viral infection that persists in the brain despite treatment. Approximately half of all seropositive patients will experience some degree of comorbid depression, as well as HIV associated neurocognitive disorders. The present research sought to evaluate the therapeutic efficacy of escitalopram, a selective serotonin reuptake inhibitor in ameliorating neuroanatomical and biochemical markers associated with HIV infection. The central purpose of this research is to characterize the effects of escitalopram treatment upon dendritic spine proliferation in the nucleus accumbens. Previous research has consistently demonstrated impaired synaptodendritic integrity in this region, with underlying mechanisms remaining unclear. A secondary focus …

A Closer Look Into American Humanitarian Intervention: How Understanding Humanity Tells Who And When We Help, Katie Noble 21

Honor Scholar Theses

I will focus on the United States and their motivation to aid humanitarian crises through three case studies. To realize how the United States is motivated to help, humanity’s predispositions must be well-defined, alongside their established geopolitical interests. It is easy to feel empathy for loved ones or family members, but how does empathy translate with someone in a foreign country? At our core, humans seek interaction and cooperation among others. Who and how they decide to cooperate with defines the intervention strategies. If we can understand how the individual selects their in-group, these tendencies will reflect at the state …

Criminal Mental Health, Tabitha Oliver

Senior Honors Theses

The purpose of this thesis is to assess and address the prevalence of mental health issues among incarcerated individuals in America. There are multiple internal and external contributing factors to the disproportionately high numbers of mentally ill inmates. Comparing the United States prison system with other countries such as Norway allows for possible paths to improving the mental health crisis that we are currently experiencing. This thesis looks at the principles and practices used in Norway's prisons as well as how they affect inmate's mental health. By comparing Norway's prison policies and design, this thesis will suggest changes in staff …

The Effect Of Body Region On Hair Cortisol Concentration In Common Marmosets (Callithrix Jacchus), Evelyn Elizabeth Bartling-John, Kimberley A. Phillips

Psychology Faculty Research

Common marmosets (Callithrix jacchus) are a valuable research model for the study of neuroscience and the biologic impact of aging due to their adaptivity, physiologic characteristics, and ease of handling for experimental manipulations. Quantification of cortisol in hair provides a noninvasive, retrospective biomarker of hypothalamics-pituitary-adrenal (HPA) axis activity and information on animal wellbeing, including responses to environmental and social stimuli. To obtain valid and reliable measurements of long-term HPA activity, we investigated the variability of cortisol concentration in the hair depending on the body region of marmosets. Hair was collected from the back and tail of 9 adult …

Dreadds Modulation Of Operant Behavior In Male And Female Hiv-1 Transgenic And F344/N Rats, Jessica Illenberger

Theses and Dissertations

The neurobiological processes which determine the choice between 2 (or more) reinforcers are unidentified despite the remarkable benefits which could result from better understanding or control of such processes. Most prominently, reducing choices to pursue drug over non-drug reinforcers could curtail the development or continuation of drug dependence. Likewise, increasing goal-directed behavior in single-schedule and choice settings may alleviate some of the consequences of apathy, a reduction in goal-directed behavior which can occur with neuropathologies including HIV-associated neurocognitive disorders. Dysregulation of the mesolimbic circuit, connecting the ventral tegmental area to the nucleus accumbens, has been implicated in both drug dependence …

Treatment Of Hiv-1 Associated Neurocognitive Disorders Through Mechanisms Of Neurogenesis With 11-Hour Voluntary Running Wheel Exposure, Alex Steiner

Theses and Dissertations

Individuals with HIV-1 taking combined antiretroviral therapy (cART) live longer with less morbidity associated with the infection. The increase in lifespan has created a critical need for the deterrence of HIV-1 associated neurocognitive disorders (HAND) reported in the aging population. Previous reports indicate that the HIV-1 infection may cause impairment in neurogenesis, leading to many of the cognitive deficits seen. The current paper proposes that exercise, as defined by voluntary wheel running, would be a potent inducer of neurogenesis that results in the neuro-restoration of CNS properties and cognitive functioning. Each animal had free access to 11-hour nocturnal wheel-running seven …

Having No Words For Feelings: Alexithymia As A Fundamental Personality Dimension At The Interface Of Cognition And Emotion, Olivier Luminet, Kristy A. Nielson, Nathan Ridout

Psychology Faculty Research and Publications

This special issue brings together two important reviews and seven cutting-edge empirical papers concerning the influence of alexithymia on cognitive and emotional processing. Alexithymia is a multifaceted construct that is characterised by difficulties identifying one’s feelings; difficulties describing one’s feelings to others; and an externally focused, utilitarian cognitive style. In this paper, we begin by considering how emotion science has evolved in its understanding of personality traits, before highlighting the potential importance of alexithymia research for the field of cognition and emotion. After summarising the historical context of alexithymia research, we consider the contributions of the featured papers to the …

The Impact Of Parent And Peer Socialization On Juvenile Delinquency, Ebony I. Pender

Sociology & Criminal Justice Theses & Dissertations

Juveniles often make decisions based on socialization and behaviors that are taught at a young age. Socialization experiences which can either protect or lead to adverse outcomes such as juvenile delinquency. It is extremely important to examine the role of socialization in delinquency due to the large number of youths currently involved in criminal acts. There are many violent and nonviolent crimes that are committed by youth under the ages of 18. For example, in 2018, there were 728,280 arrests of youths under the age of 18. A significant number of those, 46,410, were for violent index crimes with 141,500 …

Event-Related Potentials, Inhibition, And Risk For Alzheimer’S Disease Among Cognitively Intact Elders, Kathleen Hazlett Elverman, Elizabeth Rose Paitel, Christina Marie Figueroa, Ryan J. Mckindles, Kristy A. Nielson

Psychology Faculty Research and Publications

Background:

Despite advances in understanding Alzheimer’s disease (AD), prediction of AD prior to symptom onset remains severely limited, even when primary risk factors such as the apolipoprotein E (APOE) ɛ4 allele are known.

Objective:

Although executive dysfunction is highly prevalent and is a primary contributor to loss of independence in those with AD, few studies have examined neural differences underlying executive functioning as indicators of risk for AD prior to symptom onset, when intervention might be effective.

Methods:

This study examined event-related potential (ERP) differences during inhibitory control in 44 cognitively intact older adults (20 ɛ4+, 24 ɛ4-), …

Mechanisms, Diagnosis, Prevention And Management Of Perioperative Opioid-Induced Hyperalgesia, Sylvia H Wilson, Kevin M Hellman, Dominika James, Adam C Adler, Arvind Chandrakantan

Faculty, Staff and Students Publications

Opioid-induced hyperalgesia (OIH) occurs when opioids paradoxically enhance the pain they are prescribed to ameliorate. To address a lack of perioperative awareness, we present an educational review of clinically relevant aspects of the disorder. Although the mechanisms of OIH are thought to primarily involve medullary descending pathways, it is likely multifactorial with several relevant therapeutic targets. We provide a suggested clinical definition and directions for clinical differentiation of OIH from other diagnoses, as this may be confusing but is germane to appropriate management. Finally, we discuss prevention including patient education and analgesic management choices. As prevention may serve as the …

Effect Of Environmental Enrichment On The Brain And On Learning And Cognition By Animals, Thomas R. Zentall

Psychology Faculty Publications

The humane treatment of animals suggests that they should be housed in an environment that is rich in stimulation and allows for varied activities. However, even if one’s main concern is an accurate assessment of their learning and cognitive abilities, housing them in an enriched environment can have an important effect on the assessment of those abilities. Research has found that the development of the brain of animals is significantly affected by the environment in which they live. Not surprisingly, their ability to learn both simple and complex tasks is affected by even modest time spent in an enriched environment. …

Co -Localization Of D 1 And Darpp-32 In Methamphetamine-Treated Rat Nucleus Accumbens, Perirhinal Cortex, And Hippocampus, Yonca Cam

Theses and Dissertations

Methamphetamine abuse is a major health concern that has been associated with adverseeffects such as behavioral disturbances, impaired memory, and cognitive deficits. Chronic use of methamphetamine has been found to cause persistent changes in dopamine receptors and DARPP-32 expression in the rat striatum. Because methamphetamine use has been associated with memory and cognitive impairments, chronic effects in memory-related regions should be thoroughly examined as well. The current study investigated the long-term effects of methamphetamine self-administration on D1 receptor and DARPP-32 expression on the subregions of nucleus accumbens, hippocampus, and perirhinal cortex via immunostaining. I expected to find decreased levels of …

Political Ideologies, Political Party Affiliation, And Treatment Decisions Of Clinical Mental Health Counselors, Aaron L. Norton

USF Tampa Graduate Theses and Dissertations

Literature in the counseling profession has emphasized the importance of recognition of the potential impact of counselor bias on clinical care for decades. A large body of research has been developed on the potential for the personal, social, and religious beliefs of clinical mental health counselors (CMHCs) to impact their work with clients, but comparatively little research has been conducted on the potential impact of the political beliefs of CMHCs and their clinical practice, creating a gap in the professional literature. The present study sought to bridge the gap in CMHC literature by examining the relationship between the political ideologies, …

Anxiety And Depression's Incremental Effect On Executive Functioning Deficits In Children And Adolescents, Paige Picou

LSU Master's Theses

Children and adolescents experiencing anxiety and/or depression experience impairment in a myriad of domains and often engage in maladaptive strategies that then exacerbate or prolong their current symptomology. However, there is still a paucity of research examining anxiety and depression’s impact on executive functioning in children and adolescents, and existing research is muddled with problems in how researchers both define and choose to measure executive functioning. This study aims to clarify some of the conflicting research on anxiety and depression’s impact on executive functioning by using Barkley’s hybrid theory of executive functioning to determine whether anxiety and depressive symptomology add …

Understanding Teacher-Child And Peer Interactions During A 12-Week Preschool Art Program, Rebecca Bove

Theses and Dissertations

Children’s social and emotional development is essential for well being (Garner & Estep, 2001). Prior research has examined the impact of teacher-child interactions on children’s school adjustment, but little research has been done to explore how certain behaviors children demonstrate with teachers influence peer interactions (Graves Jr. & Howes, 2011; Rudasill et al., 2013). The goal of the study was to examine whether the proportion of interactions and the positive or negative connotation of the interactions that a child had with teachers had an impact on social-emotional relations with peers. Using archival observational data collected while children participated in a …

Creatine And Cognitive Functioning: What Is The Role Of Exercise Frequency?, Jonathan B. Banks, Jose Antonio, Amanda S. Holtzman, Mykola Marang, Catherine Weber, Alexsandra Alvarez-Beaton, Aysha Patel, Jaime Tartar

Journal for Sports Neuroscience

Creatine consumption appears to have a positive impact on cognitive function in different populations but the effects of creatine in a young, healthy population are mixed. Additionally, exercise appears to benefit cognitive processes in young and older adults. The present study explored the ways in which exercise frequency may moderate the effect of creatine consumption on working memory, sustained attention, mind wandering, and speed of processing, in a young, healthy, adult population. Forty-two individuals were randomly assigned to a creatine condition (n = 20) or a control condition (n = 22). For each session, participants completed the Symmetry …

Predictors Of Separation Anxiety In Dogs, Mckenna Yohe

Honors Program: Senior Projects (Public)

Understanding the potential causes and risk factors associated with separation anxiety in dogs is necessary to provide insight for possible prevention measures and to maintain the health and well-being of the animals affected by this condition. While a considerable amount of research has been done on this subject, it is still unclear what specific characteristics of dogs and their owners relate to the occurrence of separation anxiety and related behaviors. This study aimed to reexamine several dog and owner characteristics that have previously been evaluated in relation to the incidence of separation anxiety, as well as investigate how the frequency …

The Origins Of Religious Disbelief: A Dual Inheritance Approach, Will M. Gervais, Maxine B. Najle, Nava Caluori

Psychology Graduate Research

Widespread religious disbelief represents a key testing ground for theories of religion. We evaluated the predictions of three prominent theoretical approaches—secularization, cognitive byproduct, and dual inheritance—in a nationally representative (United States, N = 1,417) data set with preregistered analyses and found considerable support for the dual inheritance perspective. Of key predictors of religious disbelief, witnessing fewer credible cultural cues of religious commitment was the most potent, β = .28, followed distantly by reflective cognitive style, β = .13, and less advanced mentalizing, β = .05. Low cultural exposure predicted about 90% higher odds of atheism than did peak cognitive reflection, …

Hp Windows Mixed Reality Vs Meta 2: Investigating Differences In Workload And Usability For A Ball-Sorting Task, Joseph Pruitt, Melissa Marques, Hannah Singer, Amber Blatchford

The Pegasus Review: UCF Undergraduate Research Journal

Perceived workload and usability are crucial components of human-computer interactions. Currently, there is a gap in research comparing Augmented Reality (AR) and Virtual Reality (VR) systems for workload and usability. This study attempts to bridge that gap through the comparison of the HP Windows Mixed Reality system and the Meta 2 system for a ball-sorting task. Subjective questionnaires on workload and usability were implemented as comparative measures for three game scenarios of increasing difficulty. Forty-one participants were recruited from the University of Central Florida and its surrounding communities. Results showed significantly lower cumulative total workload and greater usability (for the …

Putting The Self In Self-Correction: Findings From The Loss-Of-Confidence Project, Julia M. Rohrer, Warren Tierney, Eric L. Uhlmann, Lisa M. Debruine, Tom Heyman, Benedict Jones, Stefan C Schmukle, Raphael Silberzahn, Rebecca M. Willén, Rickard Carlsson, Richard E. Lucas, Julia Strand, Simine Vazire, Jessica K. Witt, Thomas R. Zentall, Christopher F. Chabris, Tal Yarkoni

Psychology Faculty Publications

Science is often perceived to be a self-correcting enterprise. In principle, the assessment of scientific claims is supposed to proceed in a cumulative fashion, with the reigning theories of the day progressively approximating truth more accurately over time. In practice, however, cumulative self-correction tends to proceed less efficiently than one might naively suppose. Far from evaluating new evidence dispassionately and infallibly, individual scientists often cling stubbornly to prior findings. Here we explore the dynamics of scientific self-correction at an individual rather than collective level. In 13 written statements, researchers from diverse branches of psychology share why and how they have …

Development Of The Sexual Shame Inventory, Jyssica Seebeck

Clinical Psychology Dissertations

Researchers have speculated about the existence of sexual shame, both theoretically and clinically. It has been suggested that sexual shame is maladaptive and influences implications and treatment for shame. However, no valid measure existed to assess these claims. As such, I designed and tested the Sexual Shame Inventory (SSI)– a measure that assesses the domain-specific construct of sexual shame. An initial pool of 35 items were informed through a deductive approach. The scale was completed by a sample of individuals 18 years and older (N = 281). The majority of the sample identified as female, white, heterosexual, and married …

Oxytocin And Addiction: Potential Glutamatergic Mechanisms, Megana Sundar, Devon Patel, Zachary Young, Kah-Chung Leong

Psychology Faculty Research

Recently, oxytocin (OXT) has been investigated for its potential therapeutic role in addiction. OXT has been found to diminish various drug-seeking and drug-induced behaviors. Although its behavioral effects are well-established, there is not much consensus on how this neuropeptide exerts its effects. Previous research has given thought to how dopamine (DA) may be involved in oxytocinergic mechanisms, but there has not been as strong of a focus on the role that glutamate (Glu) has. The glutamatergic system is critical for the processing of rewards and the disruption of glutamatergic projections produces the behaviors seen in drug addicts. We introduce the …

Noncompliance With Safety Guidelines As A Free-Riding Strategy: An Evolutionary Game-Theoretic Approach To Cooperation During The Covid-19 Pandemic, Jose C. Yong, Bryan K. C. Choy

Research Collection School of Social Sciences

Evolutionary game theory and public goods games offer an important framework to understand cooperation during pandemics. From this perspective, the COVID-19 situation can be conceptualized as a dilemma where people who neglect safety precautions act as free riders, because they get to enjoy the benefits of decreased health risk from others' compliance with policies despite not contributing to or even undermining public safety themselves. At the same time, humans appear to carry a suite of evolved psychological mechanisms aimed at curbing free riding in order to ensure the continued provision of public goods, which can be leveraged to develop more …

Assisted Reproductive Technologies And Health-Related Issues Among Women And Children: A Research Review, Laura Maria Corradi

Dignity: A Journal of Analysis of Exploitation and Violence

From their first use in the late 1970s until the mid-1990s, Assisted Reproductive Technologies (ART) gave rise to serious concerns by feminists internationally. Their questions ranged from asking about health risks to ethical and political problems inherent in these technologies. However, over the last 25 years, interest in women’s health which used to be central to feminist theory and politics, progressively decreased and with it concerns about ART. Today, while the medical literature about health risks in ART is increasing, the topic of women’s health in relation to reproductive technologies remains marginal in feminist discourse, social sciences, and the mainstream …

The Human Instinct To Resilience: Clinical And Evolutionary Efficacy Of Intrinsically Motivated Stressor Exposure, Brady Barley

Ramifications

Environmental stressors threaten optimal behavioral functioning, and thus contribute to the development of psychopathology and exert evolutionary selection pressure. Voluntary stressor exposure has the efficacious effect of increasing resilience to future stressors in humans and other animals. This theoretical paper considers the hypothesis that intrinsic motivation toward behaviors requiring voluntary stressor exposure mitigates evolutionary selection pressure exerted by environmental stressors by inducing neural and neuroendocrine plasticity which results in increased resilience. In this view, intrinsically motivated stressor exposure is both efficacious and innate. Empirical and theoretical support for this hypothesis suggest that humans possess an instinct to resilience. Stress-related disorders …

A Study Investigating Depictions Of Workplace Bullying In Hollywood Films, Alexia Georgakopoulos, Maria Georgo

Peace and Conflict Studies Journal Conference

The presentation will focus on the investigative portrayal and depiction of workplace bullying from a sample of 100 popular Hollywood films over the past two decades. It will highlight the theoretical underpinnings of film theory, social construction theory, and symbolic interaction theory. The Hymes’ SPEAKING Model, a well-established ethnographic communication method (Hymes, 1974), will also be discussed because of its rich interpretive and descriptive nature and its focus on analyzing communication and interaction in terms of both verbal and nonverbal exchanges. The findings shed new light on understanding the portrayals of workplace bullying in contemporary films and how this impacts …

The Comparative Psychology Of Intelligence: Macphail Revisited, Michael Colombo, Damian Scarf, Thomas R. Zentall

Psychology Faculty Publications

No abstract provided.

Aberrant Maturation Of The Uncinate Fasciculus Follows Exposure To Unpredictable Patterns Of Maternal Signals, Steven J. Granger, Laura M. Glynn, Curt A. Sandman, Steven L. Small, Andre Obenaus, David B. Keator, Tallie Z. Baram, Hal S. Stern, Michael A. Yassa, Elyssia Poggi Davis

Psychology Faculty Articles and Research

Across species, unpredictable patterns of maternal behavior are emerging as novel predictors of aberrant cognitive and emotional outcomes later in life. In animal models, exposure to unpredictable patterns of maternal behavior alters brain circuit maturation and cognitive and emotional outcomes. However, whether exposure to such signals in humans alters the development of brain pathways is unknown. In mother–child dyads, we tested the hypothesis that exposure to more unpredictable maternal signals in infancy is associated with aberrant maturation of corticolimbic pathways. We focused on the uncinate fasciculus, the primary fiber bundle connecting the amygdala to the orbitofrontal cortex and a key …

The Rac-Gef Tiam1 Promotes Dendrite And Synapse Stabilization Of Dentate Granule Cells And Restricts Hippocampal-Dependent Memory Functions, Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolias

Faculty, Staff and Students Publications

The dentate gyrus (DG) controls information flow into the hippocampus and is critical for learning, memory, pattern separation, and spatial coding, while DG dysfunction is associated with neuropsychiatric disorders. Despite its importance, the molecular mechanisms regulating DG neural circuit assembly and function remain unclear. Here, we identify the Rac-GEF Tiam1 as an important regulator of DG development and associated memory processes. In the hippocampus, Tiam1 is predominantly expressed in the DG throughout life. Global deletion of Tiam1 in male mice results in DG granule cells with simplified dendritic arbors, reduced dendritic spine density, and diminished excitatory synaptic transmission. Notably, DG …

Child Life Specialists’ Evaluation Of Hospital Playroom Design: A Mixed Method Inquiry, Nanci Weinberger, Allison Butler, Beth Mcgee, Phyllis A. Schumacher, Ryan Linn Brown

Applied Psychology Department Faculty Journal Articles

This study uses the expertise of child life specialists to identify which elements support child life goals for hospitalized children. This study can be used to inform those interested in the optimal design of hospital playrooms. Ninety child life specialists were surveyed using a photograph methodology showing five actual child life playrooms from different hospitals. The participants were asked the following: rate each playroom on 14 dimensions; describe what was liked best about each playroom; and finally, rank order the playrooms based on their ability to support child life goals. Findings show that child life specialists were able to detect …