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Sex Differences In Lateral Hypothalamic Extracellular Glucose Concentrations During Cumulative Dosing Of Methamphetamine In Rats, Joshua A. Jolton Apr 2022

Sex Differences In Lateral Hypothalamic Extracellular Glucose Concentrations During Cumulative Dosing Of Methamphetamine In Rats, Joshua A. Jolton

Honors Program: Senior Projects (Public)

The present study experimentally investigated sex differences in lateral hypothalamic glucose concentrations following cumulative dosing of methamphetamine. Male (n=17) and female (n=11) rats were surgically implanted with enzyme-based glucose biosensors in the lateral hypothalamus. Rats then received a saline injection followed by four methamphetamine doses (0.025 mg/kg, 0.05 mg/kg, 0.1 mg/kg, and 0.2 mg/kg) spaced 55 minutes apart. We found that while there was a general decrease in glucose baseline throughout the study for both sexes, the magnitude of the decrease was significantly greater in females compared to males. On a rapid timescale, fixed sex effects existed at the lower …


Nature And Perspective On God: The Differential Impact Of Long Versus Short Adventure Programming For College Students, Alexandra Heinle Apr 2022

Nature And Perspective On God: The Differential Impact Of Long Versus Short Adventure Programming For College Students, Alexandra Heinle

Doctor of Psychology (PsyD)

This clinical dissertation focused on the shift in one’s perception of God after time spent in nature in the context of a spiritual adventure program. There are studies that find spiritual adventure programs increase a participant’s spirituality (Bobilya, 2011). However, there is a gap in the literature surrounding how spiritual outdoor programs, specifically the one in this study, influences a person’s God-image. This dissertation aims to close the gap in research regarding spiritual adventure programs and shift in God-image by studying if a person’s image of God shifts after time spent in nature, and if it shifts differently depending on …


The Importance Of Timing In Repeated Traumatic Brain Injury, Willie L. Hardeman Iii Apr 2022

The Importance Of Timing In Repeated Traumatic Brain Injury, Willie L. Hardeman Iii

Loma Linda University Electronic Theses, Dissertations & Projects

Repeated closed-head traumatic brain injury (rTBI) can result in serious consequences, such as the development of neurodegenerative diseases like Alzheimer’s Disease (AD), chronic traumatic encephalopathy (CTE), and many others. This study characterizes the consequences of injury timing in a Drosophila melanogaster model of rTBI. Specifically, each fly was subjected to 4 strikes with a modified “high impact trauma” (HIT) device. The strikes were separated by either 5 minutes, 2 hours, 4 hours, or 36 hours. These inter-strike intervals theoretically provided an opportunity to study outcomes of repeated brain injury during times of unresolved rTBI mechanisms. Half of the flies were …


The Mental Noise Hypothesis: A Relation Between Neuroticism And P3 Latency Variance In A Stroop-Style Reaction Time Task, Jeremy Lawrence Apr 2022

The Mental Noise Hypothesis: A Relation Between Neuroticism And P3 Latency Variance In A Stroop-Style Reaction Time Task, Jeremy Lawrence

All NMU Master's Theses

Neuroticism is a relatively stable personality dimension characterized by tendencies to experience negative thoughts and affect. Its empirically related outcome measures range from anxiety and mood disorders to increases in mortality. Traditional theories of neuroticism, link the construct to greater threat sensitivity, however, these conceptions fail to account for certain salient features of neuroticism, such as negative affect in threat benign environments. The mental noise hypothesis posits that neuroticism results from a more variable mental control system, with support coming from behavioral, psychometric, and neuroimaging paradigms. To assess whether this more chaotic mental control system would variably disrupt the stimulus …


Perceptions Of Emotional Functionality: Similarities And Differences Among Dignity, Face, And Honor Cultures, Maitner A.T., Decoster J., Andersson P.A., Eriksson K., Sherbaji S., Giner-Sorolla R., Mackie D.M., Aveyard M., Claypool H.M., Crisp R.J., Gritskov V., Habjan K., Andree Hartanto, Kiyonari T., Kuzminska A.O., Manesi Z., Molho C., Munasinghe A., Peperkoorn L.S., Shiramizu V. Apr 2022

Perceptions Of Emotional Functionality: Similarities And Differences Among Dignity, Face, And Honor Cultures, Maitner A.T., Decoster J., Andersson P.A., Eriksson K., Sherbaji S., Giner-Sorolla R., Mackie D.M., Aveyard M., Claypool H.M., Crisp R.J., Gritskov V., Habjan K., Andree Hartanto, Kiyonari T., Kuzminska A.O., Manesi Z., Molho C., Munasinghe A., Peperkoorn L.S., Shiramizu V.

Research Collection School of Social Sciences

Emotions are linked to wide sets of action tendencies, and it can be difficult to predict which specific action tendency will be motivated or indulged in response to individual experiences of emotion. Building on a functional perspective of emotion, we investigate whether anger and shame connect to different behavioral intentions in dignity, face, and honor cultures. Using simple animations that showed perpetrators taking resources from victims, we conducted two studies across eleven countries investigating the extent to which participants expected victims to feel anger and shame, how they thought victims should respond to such violations, and how expectations of emotions …


Kindness In The Bardo: Empathy As A Catalyst For Healing In Victims Of Dissociation, Julia Dorothea Chopelas Apr 2022

Kindness In The Bardo: Empathy As A Catalyst For Healing In Victims Of Dissociation, Julia Dorothea Chopelas

Criterion: A Journal of Literary Criticism

In George Saunders’ Lincoln in the Bardo, a host of undead characters find themselves in a spiritual limbo based on the bardo. Although they won’t admit it to themselves, Roger Bevins III and Hans Vollman are most certainly dead. Despite their supernatural makeup as ghosts, Bevins and Vollman bear strong psychological resonance with the living: they are human, heartbroken, and lost. For the ghosts of Oak Hills Cemetery, the inefficient coping mechanism of dissociation perpetuates their afterlife imprisonment in the bardo. Bevins and Vollman suffer from a variety of dissociative symptoms, their minds’ psychological defense against the trauma that has …


Further Investigating Suggestibility And False Memory, Angelina M. Blanchette Apr 2022

Further Investigating Suggestibility And False Memory, Angelina M. Blanchette

Honors College Theses

This study investigated suggestibility in the context of effects of misinformation on memory. In the current study, participants viewed a video followed by comprehension questions followed by two sets of true/false questions and then the same set of comprehension questions including information in the true/false questions that was inconsistent with the video and comprehension questions negatively affected memory compared to the control condition. These findings are discussed in terms of theories relating to how misinformation affects memory.


Recently Integrated Alu Elements In Capuchin Monkeys: A Resource For Cebus/Sapajus Genomics, J. M. Storer, J. A. Walker, C. E. Rockwell, G. Mores, T. O. Beckstrom, J. D. Orkin, A. D. Melin, Kimberley A. Phillips, C. Roos, M. A. Batzer Apr 2022

Recently Integrated Alu Elements In Capuchin Monkeys: A Resource For Cebus/Sapajus Genomics, J. M. Storer, J. A. Walker, C. E. Rockwell, G. Mores, T. O. Beckstrom, J. D. Orkin, A. D. Melin, Kimberley A. Phillips, C. Roos, M. A. Batzer

Psychology Faculty Research

Capuchins are platyrrhines (monkeys found in the Americas) within the Cebidae fam-ily. For most of their taxonomic history, the two main morphological types of capuchins, gracile (untufted) and robust (tufted), were assigned to a single genus, Cebus. Further, all tufted capuchins were assigned to a single species, Cebus apella, despite broad geographic ranges spanning Central and northern South America. In 2012, tufted capuchins were assigned to their genus, Sapajus, with eight currently recognized species and five Cebus species, although these numbers are still under debate. Alu retrotransposons are a class of mobile element insertion (MEI) widely used …


Fire Prevention Education For Boys And Girls Who Misuse Fire: A Quasi-Experimental Mixed Methods Analysis Of Effective Intervention Programming, Matthew B. Ferdock Apr 2022

Fire Prevention Education For Boys And Girls Who Misuse Fire: A Quasi-Experimental Mixed Methods Analysis Of Effective Intervention Programming, Matthew B. Ferdock

Doctoral Dissertations and Projects

A child referred for an assessment following fire misuse (e.g., setting a fire intentionally) triggers an intervention strategist who constructs a program that almost universally includes fire safety education (FSE). While FSE media tailored by age and grade is available from the U.S. Federal Government, most youth fire misuse intervention educational programming differentiates children by age. However, program designers rarely consider gender, racial differences, and socioeconomic factors during education design and delivery. Limited research demonstrates efficacious FSE. However, since almost no FSE accounts for differences beyond age, no empirical evidence exists examining its efficacy by demographic or socioeconomic differences. Using …


S-Equol: A Novel Therapeutic For Hiv-1 Induced Gut Dysbiosis, Mason T. Rodriguez Apr 2022

S-Equol: A Novel Therapeutic For Hiv-1 Induced Gut Dysbiosis, Mason T. Rodriguez

Theses and Dissertations

HIV-1 infection affects approximately 38 million people around the world. The advent of cART has greatly improved the quality of life of infected individuals; however, roughly 50% of these individuals will still experience HIV-1 associated neurocognitive disorders (HAND). Additionally, the gut microbiome has been reported to be dysbiotic in HIV-1 infected individuals, regardless of adherence to cART. Current research has pointed to the gut-brain-microbiota axis as a potential target to treat both cognitive deficits and microbial changes. The present study investigated S-equol (SE) as a potential therapeutic for HAND by modulating the gut microbiome. The study included 21 HIV-1 Tg …


Effects Of Gamification On Knowledge Acquisition: Aviation Weather Online Training, Jacqueline Mcsorley Apr 2022

Effects Of Gamification On Knowledge Acquisition: Aviation Weather Online Training, Jacqueline Mcsorley

Doctoral Dissertations and Master's Theses

Due to the high popularity of gaming, researchers have begun to implement aspects of these games into real life (known as gamification). Motivation and engagement may be influenced by certain game mechanics and user types, which then could also impact learning. A gap still exists as to whether leaderboards and narratives impact motivation or engagement when implemented in a non-game context (i.e., an online training program). Studies indicate that aviation weather training for general aviation pilots is underdeveloped, particularly for NEXRAD. In considering the competitive/ goal-oriented nature of pilots, gamification elements such as Achievements and Stories could best motivate pilots-in-training …


Level Up: Examining The Effects Of Sexualized Video Game Characters, Sarah D. Lethbridge Apr 2022

Level Up: Examining The Effects Of Sexualized Video Game Characters, Sarah D. Lethbridge

Selected Honors Theses

Characters in video games, especially female characters, are often designed or depicted to be sexually attractive. These characters are sexualized by exaggerated body proportions, revealing clothing, and behavior. There are a variety of methods by which players could be impacted by these sexualized characters, including the mere exposure effect, Proteus effect, and avatar identification. The increase of video game usage and sales in recent years, specifically among the COVID-19 pandemic, brings a greater need to understand the effects of these video games. Little research currently exists on the topic, and often provides conflicting data. The current study enlisted volunteers to …


Replication Of A Skills Assessment For Auditory–Visual Conditional Discrimination Training, Tiffany Kodak, Samantha Bergmann, Maria Clara Cordeiro, Meredity Bamond, Robert W. Isenhower, Kate E. Fiske Apr 2022

Replication Of A Skills Assessment For Auditory–Visual Conditional Discrimination Training, Tiffany Kodak, Samantha Bergmann, Maria Clara Cordeiro, Meredity Bamond, Robert W. Isenhower, Kate E. Fiske

Psychology Faculty Research and Publications

Auditory–visual conditional discrimination training (e.g., receptive identification training, listener responses; AVCD) is ubiquitous in early intervention and special education programs. Nevertheless, some learners with Autism Spectrum Disorder (ASD) do not appear to benefit from this training despite use of empirically validated treatments. To prevent exposure to extended training that does not lead to learning, a skills assessment that measures skills related to AVCD training will be useful for educators and practitioners. The current study replicated the skills assessment developed and evaluated by Kodak et al. (2015) with 8 participants with ASD who received behavior analytic intervention that included at least …


Executive Function Moderates The Effect Of Reappraisal On Life Satisfaction: A Latent Variable Analysis, Wei Xing Toh, Hwajin Yang Apr 2022

Executive Function Moderates The Effect Of Reappraisal On Life Satisfaction: A Latent Variable Analysis, Wei Xing Toh, Hwajin Yang

Research Collection School of Social Sciences

Emotion regulation strategies, such as reappraisal and suppression, have been shown to dissimilarly affect life satisfaction. Specifically, reappraisal is linked to higher life satisfaction, while suppression is associated with lower life satisfaction. Less is known, however, about the potential moderators of these established relations. Given that reappraisal and suppression are contingent, in part, on executive function (EF), which comprises a group of adaptive, goal-orientated control processes (i.e., inhibitory control, working memory, and shifting), we explored whether different components of EF could moderate the impact of reappraisal and suppression on life satisfaction. Using latent moderated structural equation analyses, we found that …


Individual Differences In Response To Hostile And Benevolent Sexism In A Stem Interview Context: The Moderating Role Of Behavioral Activation, Elizabeth Kiebel Mar 2022

Individual Differences In Response To Hostile And Benevolent Sexism In A Stem Interview Context: The Moderating Role Of Behavioral Activation, Elizabeth Kiebel

USF Tampa Graduate Theses and Dissertations

Women continue to face sexism in workplace contexts, especially those that are male dominated, such as science, technology, engineering, and mathematics (STEM). Yet, women often fail to confront the sexism they experience, despite confrontation being an effective way to cope with and prevent future harassment (Fitzgerald et al., 1995; Magley, 2002). To date, no one has assessed the potential moderating role of personality differences related to approach motivation on women’s confrontation of sexism. In this study, women were exposed to either a hostilely sexist or benevolently sexist question during a mock job interview that was purportedly being conducted as part …


Vedantic Basis And Praxis Of The Integral Advaita Of Sri Aurobindo, Debashish Banerji Mar 2022

Vedantic Basis And Praxis Of The Integral Advaita Of Sri Aurobindo, Debashish Banerji

Monsoon: South Asian Studies Association Journal

The integral nondualism of Sri Aurobindo can be traced to the great pronouncements (mahāvākya) of the Upanishads and later commentaries. This study examines teachings on the Supermind (vijñāna) and the other four kinds of consciousness that define human reality: Matter (annaṃ), Life (prāṇaḥ), Mind (manaḥ), and Bliss (ānanda). Through Yoga and Tantra, one learns and embodies the pathway to the divine.


Digital And Spatial Humanities Mapping: Eurasia-Pacific Early Trade And Belief Linkages, Igor Sitnikov, David Blundell Mar 2022

Digital And Spatial Humanities Mapping: Eurasia-Pacific Early Trade And Belief Linkages, Igor Sitnikov, David Blundell

Monsoon: South Asian Studies Association Journal

The Eurasia-Pacific is a dynamic region of rapid economic growth, cultural awareness, natural resource exploration, and military buildup. The concept of the region is relatively new, featuring contested vast areas of geo-resource space of numerous cultures and languages. The current findings in anthropology and archaeology and even its more specific subfields such as folklore are important contribution to the understanding of periodic environmental changes and technical innovations were the main forces of transformations in social structures that have determined the mechanisms and levels of cross-cultural trade activity across the region. We have traced early trade and belief linkages across Eurasia-Pacific …


Diversity, Equity, And Inclusion: Perspectives From Contemporary India And 6th Century Jain Yoga, Christopher Key Chapple Mar 2022

Diversity, Equity, And Inclusion: Perspectives From Contemporary India And 6th Century Jain Yoga, Christopher Key Chapple

Monsoon: South Asian Studies Association Journal

Times New Roman


Ganges In Indian Sculpture And Literature: Mythology And Personification, Nalini Rao Mar 2022

Ganges In Indian Sculpture And Literature: Mythology And Personification, Nalini Rao

Monsoon: South Asian Studies Association Journal

The river Ganges is a symbol of wealth, purity and eternity, and its sacred waters have inspired sages, philosophers, and artists in India who have immortalized its divine imagery. However, it has rarely been understood from a historical point of view, as to how it became so sacred and to view it from a multi-dimensional and interdisciplinary perspective with an accumulation of layers of historical thought and practices, provides a rationale for the living practices around the river. The paper explores the evolution of the concept of sacredness and eternity of River Ganges through art- historical and archaeological evidence. It …


Consensus Definition Of Misophonia: A Delphi Study, Susan E. Swedo, David M. Baguley, Damiaan Denys, Laura J. Dixon, Mercede Erfanian, Alessandra Fioretti, Pawel J. Jastreboff, Sukhbinder Kumar, M. Zachary Rosenthal, Romke Rouw, Daniela Schiller, Julia Simner, Eric A. Storch, Steven Taylor, Kathy R. Vander Werff, Cara M. Altimus, Sylvina M. Raver Mar 2022

Consensus Definition Of Misophonia: A Delphi Study, Susan E. Swedo, David M. Baguley, Damiaan Denys, Laura J. Dixon, Mercede Erfanian, Alessandra Fioretti, Pawel J. Jastreboff, Sukhbinder Kumar, M. Zachary Rosenthal, Romke Rouw, Daniela Schiller, Julia Simner, Eric A. Storch, Steven Taylor, Kathy R. Vander Werff, Cara M. Altimus, Sylvina M. Raver

Faculty and Student Publications

Misophonia is a disorder of decreased tolerance to specific sounds or their associated stimuli that has been characterized using different language and methodologies. The absence of a common understanding or foundational definition of misophonia hinders progress in research to understand the disorder and develop effective treatments for individuals suffering from misophonia. From June 2020 through January 2021, the authors conducted a study to determine whether a committee of experts with diverse expertise related to misophonia could develop a consensus definition of misophonia. An expert committee used a modified Delphi method to evaluate candidate definitional statements that were identified through a …


The Need To Address Religious Diversity At Work: An All-Inclusive Model Of Spirituality At Work, Ivonne Valero Cázares Mar 2022

The Need To Address Religious Diversity At Work: An All-Inclusive Model Of Spirituality At Work, Ivonne Valero Cázares

USF Tampa Graduate Theses and Dissertations

This thesis discusses the importance of embracing religion and spirituality in the workplace as an aspect of workplace diversity. This document aims to help us understand the definition of spirituality at the workplace and its constituents.

We conducted a literature review from predominant scholars about the salience of spirituality and religion at the workplace and its relevance to building meaning, connectedness, and a sense of belonging. We will also review Maslow's theory of Human Needs, his research on human peak-experiences, and its correlation to self-actualization and transcendence.

We will present a new model of Spirituality and Religion at the workplace …


Word Imageability Is Associated With Expressive Vocabulary In Children With Autism Spectrum Disorder, Kimberly R. Lin, Lisa Wisman Weil, Audrey Thurm, Catherine Lord, Rhiannon Luyster Mar 2022

Word Imageability Is Associated With Expressive Vocabulary In Children With Autism Spectrum Disorder, Kimberly R. Lin, Lisa Wisman Weil, Audrey Thurm, Catherine Lord, Rhiannon Luyster

Emerson Authors, Researchers, & Creators

Throughout typical development, children prioritize different perceptual, social, and linguistic cues to learn words. The earliest acquired words are often those that are perceptually salient and highly imageable. Imageability, the ease in which a word evokes a mental image, is a strong predictor for word age of acquisition in typically developing (TD) children, independent of other lexicosemantic features such as word frequency. However, little is known about the effects of imageability in children with autism spectrum disorder (ASD), who tend to have differences in linguistic processing and delayed language acquisition compared to their TD peers. This study explores the extent …


Executive Function In The Classroom, Dr. Kaylin Coody Coody Mar 2022

Executive Function In The Classroom, Dr. Kaylin Coody Coody

National Youth Advocacy & Resilience Conference

Do you have students in your classroom who have difficulty with working memory, inhibitory control and cognitive flexibility? These are indicators of struggling with executive function. This session will cover the brain-implications and concrete strategies to work with students at all grade levels.


Selectivity And Sociality: Aggression And Affiliation Shape Vole Social Relationships, Nicole S. Lee, Annaliese K. Beery Mar 2022

Selectivity And Sociality: Aggression And Affiliation Shape Vole Social Relationships, Nicole S. Lee, Annaliese K. Beery

Psychology: Faculty Publications

The formation of selective social relationships is not a requirement of group living; sociality can be supported by motivation for social interaction in the absence of preferences for specific individuals, and by tolerance in place of social motivation. For species that form selective social relationships, these can be maintained by preference for familiar partners, as well as by avoidance of or aggression toward individuals outside of the social bond. In this review, we explore the roles that aggression, motivation, and tolerance play in the maintenance of selective affiliation. We focus on prairie voles (Microtus ochrogaster) and meadow voles (Microtus pennsylvanicus) …


Does Optic Flow Provide Information About Actions?, Hannah Masoner Mar 2022

Does Optic Flow Provide Information About Actions?, Hannah Masoner

Dissertations

Optic flow, the pattern of light generated in the visual field by motion of objects and the observer’s body, serves as information that underwrites perception of events, actions and affordances. This visual pattern informs the observer about their own actions in relation to their surroundings, as well as those of others. This study explored the limits of action detection for others as well as the role of optic flow. First-person videos were created using camera recordings of the actor’s perspective as they performed various movements (jumping jacks, jumping, squatting, sitting, etc.). In three experiments participants attempted to detect the action …


Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley Mar 2022

Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley

LSU Doctoral Dissertations

Post-traumatic stress disorder (PTSD) is associated with elevated allostatic load, nearly double the risk for metabolic syndrome, reduced hippocampal volume, and contextual memory processing deficits. Emerging evidence suggests that these stress effects may predispose individuals to the development of PTSD, and there is a known relationship between chronic stress and metabolic dysfunction. In this work, we utilized two rat models of PTSD to explore these connections. We used an acute predator odor stressor to investigate the relationship between PTSD-like behaviors and mitochondrial dysfunction in the hippocampus of rats, and we observed that conditioned place avoidance was associated with reduced mitochondrial …


Emergent Intra-Pair Sex Differences And Organized Behavior In Pair Bonded Prairie Voles (Microtus Ochrogaster), Liza E. Brusman, David S.W. Protter, Allison C. Fultz, Maya U. Paulson, Gabriel D. Chapel, Isaiah O. Elges, Ryan T. Cameron, Annaliese K. Beery, Zoe R. Donaldson Mar 2022

Emergent Intra-Pair Sex Differences And Organized Behavior In Pair Bonded Prairie Voles (Microtus Ochrogaster), Liza E. Brusman, David S.W. Protter, Allison C. Fultz, Maya U. Paulson, Gabriel D. Chapel, Isaiah O. Elges, Ryan T. Cameron, Annaliese K. Beery, Zoe R. Donaldson

Psychology: Faculty Publications

In pair bonding animals, coordinated behavior between partners is required for the pair to accomplish shared goals such as raising young. Despite this, experimental designs rarely assess the behavior of both partners within a bonded pair. Thus, we lack an understanding of the interdependent behavioral dynamics between partners that likely facilitate relationship success. To identify intra-pair behavioral correlates of pair bonding, we used socially monogamous prairie voles (Microtus ochrogaster) and tested both partners using social choice and non-choice tests at short- and long-term pairing timepoints. Females developed a preference for their partner more rapidly than males, with preference driven by …


Sex Differences In The Reward Value Of Familiar Mates In Prairie Voles, Daniel M. Vahaba, Emily R. Halstead, Zoe R. Donaldson, Todd H. Ahern, Annaliese K. Beery Mar 2022

Sex Differences In The Reward Value Of Familiar Mates In Prairie Voles, Daniel M. Vahaba, Emily R. Halstead, Zoe R. Donaldson, Todd H. Ahern, Annaliese K. Beery

Psychology: Faculty Publications

The rewarding properties of social interactions facilitate relationship formation and maintenance. Prairie voles are one of the few laboratory species that form selective relationships, manifested as “partner preferences” for familiar partners versus strangers. While both sexes exhibit strong partner preferences, this similarity in outward behavior likely results from sex-specific neurobiological mechanisms. We recently demonstrated that in operant trials, females worked hardest for access to familiar conspecifics of either sex, while males worked equally hard for access to any female, indicating a sex difference in social motivation. As tests were performed with one social target at a time, males might have …


Pervasive Neglect Of Sex Differences In Biomedical Research, Irving Zucker, Brian J. Prendergast, Annaliese K. Beery Mar 2022

Pervasive Neglect Of Sex Differences In Biomedical Research, Irving Zucker, Brian J. Prendergast, Annaliese K. Beery

Psychology: Faculty Publications

Females have long been underrepresented in preclinical research and clinical drug trials. Directives by the U.S. National Institutes of Health have increased female participation in research protocols, although analysis of outcomes by sex remains infrequent. The long-held view that traits of female rats and mice are more variable than those of males is discredited, supporting equal representation of both sexes in most studies. Drug pharmacokinetic analysis reveals that, among subjects administered a standard drug dose, women are exposed to higher blood drug concentrations and longer drug elimination times. This contributes to increased adverse drug reactions in women and suggests that …


Factors Contributing To The Recognition Of A Potential Nonsexual Multiple Relationship, Nikki Patel Mar 2022

Factors Contributing To The Recognition Of A Potential Nonsexual Multiple Relationship, Nikki Patel

Loma Linda University Electronic Theses, Dissertations & Projects

Clinical psychologists encounter situations for which no prescriptive professional standards exist, necessitating therapists’ judgment to determine an appropriate course of action. This study examines the first step of therapists’ decision-making process—recognition of the potential for a nonsexual multiple relationship. Based on the existing literature and previous empirical findings, our hypotheses are that (1) therapist sex (female), higher scores on the PAQ Expressivity (femininity) scale, higher scores on the VIA-IS-V3 Self-control scale, and participants’ ranking Nonmaleficence as the most important ethical principle would be significantly (positively) predictive of Recognition scores, (2) higher scores on the PAQ Instrumentality (masculinity) scale, higher scores …