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The Impact Of The Gut-Brain Axis On Alzheimer’S Disease, Elissa Wakim

Best Integrated Writing

Elissa’s review for the Graduate Biomedical Review focuses on the links between the gastrointestinal tract and the brain; the gut-brain axis and the development of Alzheimer’s disease. As a student in the Microbiology and Immunology Masters Program Elissa was particularly interested in the gut microbiota and their connection to neurodegenerative disease. She tidily reviewed the literature and wrote a fascinating and compelling piece of work.

Now It’S Your Turn!: Eye Blink Rate In A Jenga Task Modulated By Interaction Of Task Wait Times, Effortful Control, And Internalizing Behaviors, Kelley E. Gunther

Faculty Publications

Dopamine is a versatile neurotransmitter with implications in many domains, including anxiety and effortful control. Where high levels of effortful control are often regarded as adaptive, other work suggests that high levels of effortful control may be a risk factor for anxiety. Dopamine signaling may be key in understanding these relations. Eye blink rate is a non-invasive proxy metric of midbrain dopamine activity. However, much work with eye blink rate has been constrained to screen-based tasks which lack in ecological validity. We tested whether changes in eye blink rate during a naturalistic effortful control task differ as a function of …

The Role Of Age And Biological Sex On Short-Term Memory In The Syrian Hamster (Mesocricetus Auratus), Laura E. Garcia, Mario Gil

Research Symposium

Background: Aging plays an important role in cognitive function, memory, and mental health. As we age, some cognitive functions become weaker. Aging is also a critical risk factor for dementia and Alzheimer’s Disease. With recent advances seen in public health, humans are living longer years. This makes it a challenge to make those added years healthy. For this reason, it is important to continue studying its effects by using, the Syrian hamster, as a model. The purpose of the study is to identify other factors that might also have a role in short-term memory, besides aging.

Methods: All behavioral …

Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil

Research Symposium

Background: Reliable, consistent, and objective data is a goal all studies aim to achieve, but many struggle to obtain when subjective biases between researchers can occur. Inter-rater reliability (IRR) is a statistical measure used to quantify the degree of agreement between researchers qualitatively scoring the same phenomenon. The primary goal of this study is to enhance the methodology used to achieve optimal IRR. Using an established ethogram, our team of researchers scored the social behavior of the adult gray short-tailed opossum (Monodelphis domestica) to propose an effective method for achieving high IRR that can contribute to future …

“My Dog Needs A Job”: Identifying The Motivations Of Therapy Animal Volunteers, Jean Kirnan, Anna Ciarrocca, Matthew Malloy, Shawne Hoehne, Grace Norris, Marc Nuzzo

People and Animals: The International Journal of Research and Practice

Volunteers provide billions of hours in free labor annually and are essential for the success of many organizations. Understanding who volunteers as well as the motivating factors that attract and retain volunteers is critical. This study explored the motivations of therapy animal volunteers (TAVs) identifying commonality with general volunteerism as well as unique motivators. Respondents were 748 TAVs with Pet Partners who completed an online survey. The Volunteer Functions Inventory (VFI) was used to allow comparisons to prior research. Supplemental items specific to animal handler motivation were added to the 30 VFI items. Additionally, participants responded to an open-ended question …

“A Robust And Simple Catheter Connector Assembly For Long-Term Self-Administration Experiments ”, Mauricio Suarez, Sergios Charntikov, Y. Wendy Huynh, Scott T. Barrett, Rick A. Bevins, Ken T. Wakabayashi

Department of Psychology: Faculty Publications

Intravenous self-administration in rats is used widely to study the reinforcing effects of drugs and serves as the gold standard for assessing their use and misuse potential. One challenge that researchers often encounter when scaling up experiments is balancing the cost, time investment to construct, and robustness of each implanted catheter. These catheters include multiple components such as surgical meshing and a variety of entry ports designed to facilitate the connection of the rat to a catheter port tethering system. Other considerations include maintaining the catheters free of blockage during the extent of the drug self-administration experiment. These large-scale studies …

Ministry Satisfaction Of Volunteers Within The Environment Of The Local Church: The Role Of Servant Leadership And Organizational Commitment, Sheena Denise Hunley

Doctoral Dissertations and Projects

In churches, it is imperative to attract, engage, and retain volunteers effectively to accomplish its mission. The impact church leaders have on volunteer satisfaction is undoubtedly far from well explored within the local church. This exploratory, qualitative case study examined the quality of church leadership’s influence on ministry satisfaction and sustained serving over time in lay volunteers. The case study took place in a non-denominational church located in East Tennessee. A central research question asked, how do lay volunteers experience satisfaction within the environment of local church and its leadership? Three research questions examined the areas of volunteer satisfaction and …

Job-Search Experiences Of Ghanaian Immigrants In New York City, Samuel Obeng

Walden Dissertations and Doctoral Studies

No abstract provided.

Gender Bias In Natural Gender Language And Grammatical Gender Language Within Children's Literature, Kaleigh Marie White Smolinski

Doctoral Dissertations and Projects

There has been much research on the connection between language and gender bias but there is little comparing natural gender language, grammatical gender language, and gender bias. This research is important because it can offer an understanding of gender bias and how these biases are reinforced in different languages. The purpose of this study is to understand how gender biases are represented in children’s literature in different languages. The research questions how gender biases are found in both natural gender and grammatical gender languages within children’s literature. Then questions if there are any differences in these biases. This study compared …

The Impact Of Monetary Incentives On Delay Discounting Within A Year-Long Physical Activity Intervention, Vincent Berardi, Christine B. Phillips, Mindy L. Mcentee, Chad Stecher, Michael Todd, Marc A. Adams

Psychology Faculty Articles and Research

Background

Delay discounting is the depreciation in a reward’s perceived value as a function of the time until receipt. Monetary incentive programs that provide rewards contingent on meeting daily physical activity (PA) goals may change participants’ delay discounting preferences. Purpose

Determine if monetary incentives provided in close temporal proximity to meeting PA goals changed delay discounting, and if such changes mediated intervention effects. Methods

Inactive adults (n = 512) wore accelerometers during a 12-month intervention where they received proximal monetary incentives for meeting daily moderate-to-vigorous PA (MVPA) goals or delayed incentives for study participation. Delay discount rate and average …

Gamma-Aminobutyric Acid (Gaba) Neurons And Perineuronal Nets (Pnn) In The Monodelphis Domestica And Relevance To Psychiatric Disorders, Jatziry Z. Luna Escobedo, Mariela Garcia, John L. Vandeberg, Mario Gil

Research Symposium

Background/ Purpose: Gamma-aminobutyric acid (GABA) is an amino acid that serves as the central nervous system’s (CNS) main inhibitory neurotransmitter. By inhibiting nerve transmission, it works to lower neuronal excitability. Altered GABA levels have been associated with a variety of psychiatric disorders, for example Epilepsies, Parkinson’s Disease, and Schizophrenia. Perineuronal nets (PNN) are extracellular molecules that are released by neurons and glial cells that modulate many neuronal and glial functions by encapsulating the inhibitory cells and neurites. Altered PNN levels serve as a potential trigger to synaptic imbalance. The purpose of this study is to quantify and analyze the presence, …

Targeting Social-Emotional Learning And Activity Attitudes During After-School Programming Post Covid-19 Restrictions, Kelly L. Simonton, Victoria N. Shiver, Aimee Gray, Katie Juarez, Angela Simonton

Journal of Youth Development

No abstract provided.

4-H Volunteers Leaders’ Turnover Intention, Suzanna R. Windon, Mariah K. Awan, Rama Radhakrishna

Journal of Youth Development

No abstract provided.

Neuroplasticity In The Dentate Gyrus: A Multimethod Investigation On Hippocampal Ltp Following Prenatal Alcohol Exposure, Monica Goncalves-Garcia

Psychology ETDs

Studies have demonstrated alcohol-related deficits in LTP associated with histaminergic and glutamatergic impairments. The histaminergic H3R inverse agonist ABT-239 has shown promise in reversing these deficits. The present study focuses on another H3R inverse agonist, SAR-152594, and its impact on LTP deficits following moderate PAE. The findings reveal that systemic administration of 1 mg/kg of SAR-152594 reverses deficits in potentiation fEPSPs in adult male rats exposed to moderate PAE. Time-frequency analyses of evoked responses indicate PAE-related reductions in power during the fEPSP and increased power during later components of evoked responses, both reversed by SAR-152594. These results provide further evidence …

The Theoretical Epigenetic Relationship Between Complex-Ptsd And Adhd In Holocaust Survivors’ Descendants, Y. Sahara Brodsky

USF Tampa Graduate Theses and Dissertations

When comparing ADHD and Complex-PTSD, these two disorders share many overlapping features in both areas of the brain that are affected and the behavioral aspects due to deficits in certain brain regions, such as the prefrontal cortex. It is due to this similarity that I predict that c-PTSD is the precursor to the development of ADHD in later generations. Through epigenetic changes that are consistent with c-PTSD diagnosis, these changes to the brain are then passed down the generational line. When this is combined with trauma transference and generational trauma, it creates a situation where both the behaviors inform how …

Techno-Legal Solutionism: Regulating Children's Online Safety In The United States, Maria P. Angel, Danah Boyd

Scholarly Works

Convinced that social media is directly harming children, policymakers have started to introduce legislation that requires technology companies to be safe by design through “duty of care” provisions. Unlike regulations that focus on product safety, these bills incorporate technosolutionist logics into regulation by presuming that technology companies can remedy complex harms like mental health duress and bullying if their products were only designed better. In this paper, we unpack the theory of change at the center of the “duty of care” included in the “Kids Online Safety Act” (KOSA). We argue that techno-legal solutionism is both ineffective as a framework …

Do Focused Interests Support Word Learning? A Study With Autistic And Nonautistic Children, Sudha Arunachalam, Amelia Steele, Taisha Pelletier, Rhiannon Luyster

Emerson Authors, Researchers, & Creators

Although focused interests are often associated with a diagnosis of autism, they are common in nonautistic individuals as well. Previous studies have explored how these interests impact cognitive, social, and language development. While some research has suggested that strong interests can detract from learning (particularly for autistic children), newer research has indicated that they can be advantageous. In this pre-registered study, we asked whether focused interests support word learning in 44 autistic children and a vocabulary-matched sample of 44 nonautistic children (mean ages 58 and 34 months respectively). In a word-learning task administered over Zoom, children were exposed to an …

Role Of Glia In Diurnal Rhythms In Neuroinflammation And Blood-Brain Barrier Breakdown, Jennifer Hoi-Ping Lawrence

Arts & Sciences Graduate Student Theses and Dissertations

While inflammation is an important mechanism for the return to homeostasis post insult or injury, inflammation in the central nervous system (CNS) can lead to irreparable damage. To mitigate this process, the brain is protected from circulating neurotoxic molecules as well as peripheral immune cells through the tightly regulated blood-brain barrier (BBB). The balance between pro- and anti- inflammation in the CNS rapidly shifts towards a neurotoxic proinflammatory state during acute bacterial or viral infections or chronic neuroinflammatory diseases. Excessive inflammatory responses are also coupled with extensive BBB leakage and breakdown, allowing rampant entry of peripheral inflammatory cells and mediators …

Now It’S Your Turn!: Eye Blink Rate In A Jenga Task Modulated By Interaction Of Task Wait Times, Effortful Control, And Internalizing Behaviors, Kelley E. Gunther, Xiaoxue Fu Ph.D., Leigha A. Macneill, Morgan Jones, Briana Ermanni, Koraly Pérez-Edgar

Faculty Publications

Dopamine is a versatile neurotransmitter with implications in many domains, including anxiety and effortful control. Where high levels of effortful control are often regarded as adaptive, other work suggests that high levels of effortful control may be a risk factor for anxiety. Dopamine signaling may be key in understanding these relations. Eye blink rate is a non-invasive proxy metric of midbrain dopamine activity. However, much work with eye blink rate has been constrained to screen-based tasks which lack in ecological validity. We tested whether changes in eye blink rate during a naturalistic effortful control task differ as a function of …

Radical Youth Work: A Community Based Approach To Working With Youth, Young Adults And Families, Weston J. Robins

National Youth Advocacy & Resilience Conference

Radical Youth Work: A Community Based Approach to Working with Youth, Young Adults and Families

A focus on experiential mentoring, humanistic counseling and community engagement as a way to work with youth, young adults and families to provide true holistic therapeutic support and guidance.

Teaching Students About Trauma, Stress And Brain Regulation, Kathy J. Van Horn

National Youth Advocacy & Resilience Conference

All students are impacted by stress and can benefit by understanding their brains, their stress response, and strategies for regulation. This presentation will provide practical principles and ideas for teaching students strategies and skills for physical, emotional, and cortical regulation.

A Genotyping Array For The Globally Invasive Vector Mosquito, Aedes Albopictus, Luciano Veiga Cosme, Margaret Corley, Thomas Johnson, Dave W Severson, Guiyun Yan, Xiaoming Wang, Nigel Beebe, Andrew Maynard, Mariangela Bonizzoni, Ayda Khorramnejad, Ademir Jesus Martins, José Bento Pereira Lima, Leonard E Munstermann, Sinnathamby N Surendran, Chun-Hong Chen, Kevin Maringer, Isra Wahid, Shomen Mukherjee, Jiannon Xu, Michael C Fontaine, Elizabet L Estallo, Marina Stein, Todd Livdahl, Patricia Y Scaraffia, Brendan H Carter, Motoyoshi Mogi, Nobuko Tuno, James W Mains, Kim A Medley, David E Bowles, Richard J Gill, Roger Eritja, Ranulfo González-Obando, Huynh T T Trang, Sébastien Boyer, Ann-Marie Abunyewa, Kayleigh Hackett, Tina Wu, Justin Nguyễn, Jiangnan Shen, Hongyu Zhao, Jacob E Crawford, Peter Armbruster, Adalgisa Caccone

Faculty, Staff and Student Publications

BACKGROUND: Although whole-genome sequencing (WGS) is the preferred genotyping method for most genomic analyses, limitations are often experienced when studying genomes characterized by a high percentage of repetitive elements, high linkage, and recombination deserts. The Asian tiger mosquito (Aedes albopictus), for example, has a genome comprising up to 72% repetitive elements, and therefore we set out to develop a single-nucleotide polymorphism (SNP) chip to be more cost-effective. Aedes albopictus is an invasive species originating from Southeast Asia that has recently spread around the world and is a vector for many human diseases. Developing an accessible genotyping platform is essential in …

Psilocybin With Acceptance And Commitment Therapy (Act) For The Treatment Of Social Anxiety Disorder (Sad), Aspen E. Allred

University Honors Theses

Social Anxiety Disorder (SAD) is a debilitating mental health condition characterized by an overwhelming fear and anxiety of social rejection that can lead to chronic patterns of social behavioral avoidance. Despite the existence of traditional efficacious treatments, a significant number of individuals either do not respond to treatment or experience a recurrence of symptoms over extended periods, spanning 10-12 years. Acceptance and Commitment Therapy (ACT), a form of acceptance-based behavioral therapy considered part of the "third wave" of cognitive behavioral therapies, has shown promising results in early studies, comparable to those of Cognitive Behavioral Therapy (CBT) that is considered the …

Spirituality In Clinical Practice: Integrating Who We Are With What We Do, Lorraine Mangione, Thomas G. Plante

Psychology

Inspired by the recent emphasis on diversity, equity, and inclusion (DEI) efforts in professional psychology and in society in general, we were interested in how personal religious and spirituality identities, practices, and traditions inform professionals in their work as clinicians and clinical supervisors and trainers to integrate who they are with what they do. The spiritual and religious intersectionality of professionals was explored by inviting 12 diverse professionals representing several different spiritual and religious traditions to reflect on their identities and the integration that they do to provide evidence-based professional services. Additionally, we asked them to consider best practices in …

Religious Stewardship And Pro-Environmental Action: The Mediating Roles Of Environmental Guilt And Anger, Shu Tian Ng, Kimin Eom

Research Collection School of Social Sciences

Past research has found that stewardship belief can motivate pro-environmentalism among religious individuals. The present study investigates the emotional pathways linking religious stewardship belief and pro-environmental policy support. In an online experiment conducted with Christians in the United States (N = 604), we experimentally primed stewardship belief (N = 195) using a video that highlighted the human responsibility to care for God’s creations. We also included a control condition (N = 206) and a religion condition (N = 203), which presented a more generic religious message. As demonstrated in a mediation model, the stewardship manipulation (vs. …

Negative Work-To-Family Spillover Stress And Heightened Cardiovascular Risk Biomarkers In Midlife And Older Adults, Andree Hartanto, K.T.A.Sandeeshwara Kasturiratna, Meilan Hu, Shu Fen Diong, Verity Y. Q. Lua

Research Collection School of Social Sciences

Objectives: The current study aimed to investigate the health implications of negative work-to-family spillover on cardiovascular risk biomarkers. Methods: In a large-scale cross-sectional dataset of working or self-employed midlife and older adults in the United States (N = 1179), we examined five biomarkers linked to cardiovascular risk, including high-density lipoprotein (HDL) cholesterol, low-density lipoprotein cholesterol, triglyceride, interleukin-6, and C-reactive protein. Negative work-to-family spillover, measured using a four-item self-reported questionnaire, was included into our model to study its association with these cardiovascular risk biomarkers. Results: Our findings indicate a significant association between negative work-to-family spillover and cardiovascular risk biomarkers – higher …

A Qualitative Phenomenological Study Of Inner Speech Used As A Self-Help Tool Among Adult Remote Workers, Jennie Yeung Dr., Jennie Yeung Dr.

Doctor of Education Program Dissertations

The COVID-19 pandemic and subsequent shift to remote work emphasized the importance of maintaining the well-being of adult remote workers. The problem studied was the awareness, understanding, and acceptance of inner speech/self-talk among adult remote workers. The purpose of this qualitative, phenomenological study was to explore the perceptions and experiences of adult remote workers regarding their use of inner speech/self-talk. Inner speech/self-talk is an innate ability of higher mental functions that include reasoning, problem solving, planning and plan execution, attention, and motivation. Data collection involved the purposeful sampling of 10 participants who were adult remote workers. The semistructured interviews were …

The Effects Of Moderate Prenatal Alcohol Exposure On Navigation In A Delayed Non- Match-To-Place Spatial Alternation Task By Adult Male And Female Rats, Gabriela Acosta

Psychology ETDs

Prenatal alcohol exposure has been found to alter brain regions involved in spatial memory. Previous studies have shown that moderate PAE (mPAE; ~30-120 mg/dL) impairs spatial memory in male rats and damages the limbic-thalamus and hippocampus. Recent work has shown that visual discrimination memory is impaired after mPAE in a sex-specific manner such that female mice exhibit greater deficits after 15sec delay. It is unclear whether similar-sex-specific deficits would be observed in a spatial memory task or in a rat model of mPAE. Thus, the present study tests the hypothesis that mPAE would produce sex-specific deficits in a delayed non-match-to-place …

Power And Control Wheel Tactics: Assessing Posttraumatic Stress Disorder (Ptsd) Epistemology Among Domestic Violence Survivors, Lisa Hady

Theses and Graduate Projects

Domestic violence affects more than 10 million adults in the United States annually (National Network to End Domestic Violence, 2020). The Power and Control Wheel (PCW) places power and control at the center of physical and sexual violence, with eight surrounding tactics representing the abusive behaviors perpetrators use to retain power and control over survivors. Although the PCW has been extended to understand various abusive relationships, and the PCW tactics have been examined in both Intimate Partner Violence (IPV) and Non-Intimate Partner Violence (NPV; Basile et al., 2004; Scott, 2018), limited research compares tactics used based on the perpetrator’s relationship …

Annual Research Review: The Power Of Predictability – Patterns Of Signals In Early Life Shape Neurodevelopment And Mental Health Trajectories, Elysia Poggi Davis, Laura M. Glynn

Psychology Faculty Articles and Research

The global burden of early life adversity (ELA) is profound. The World Health Organization has estimated that ELA accounts for almost 30% of all psychiatric cases. Yet, our ability to identify which individuals exposed to ELA will develop mental illness remains poor and there is a critical need to identify underlying pathways and mechanisms. This review proposes unpredictability as an understudied aspect of ELA that is tractable and presents a conceptual model that includes biologically plausible mechanistic pathways by which unpredictability impacts the developing brain. The model is supported by a synthesis of published and new data illustrating the significant …