Digital Commons Network^™

Benefits And Constraints Of Telepsychiatry Utilization In The United States, Bruce A. Stec, Alberto Coustasse

Management Faculty Research

This conference presentation describes the benefits and constraints of utilizing telemedicine primarily focusing on the field of psychiatry in the United States with the current system of healthcare. The utilization of telemedicine in the field of psychiatry is believed to provide better access, quality and care to the patients who necessitate psychiatric care in their overall medical care. Telemedicine has been a successfully integrated program into psychiatric facilities reaching rural, prisons or city facilities based on that it has increased the volume of patients in which physicians can reach out to and diagnose, as well as treat patients with limitations …

Drive For Muscularity And Drive For Thinness: The Impact Of Pro-Anorexia Websites, Lilia Juarez, Ernesto Soto, Mary Pritchard

Psychological Sciences Faculty Publications and Presentations

In recent years, websites that stress the message of thinness as the ideal and only choice have surfaced on the internet. The possibility that pro-anorexia websites may reinforce restrictive eating and exercise behaviors is an area of concern. In addition, friends may be influencing one another to view these websites, further contributing to drive for thinness in women and drive for muscularity in men. Three hundred male and female undergraduate psychology students responded to questionnaires assessing: internalization of pro-anorexia website content, internalization of general media content, influence of friends to view pro-anorexia websites, peer influence, drive for muscularity, and drive …

Lower Gastrointestinal Bleeding And Paroxetine Use: Two Case Reports, Hilario Blasco-Fontecilla, Jose De Leon

Psychiatry Faculty Publications

Paroxetine is a selective serotonin reuptake inhibitor (SSRI), and an effective long-term treatment for social anxiety and major depression. SSRIs in general, and paroxetine in particular, were described as associated with depletion of serotonin in platelets. Serotonin is involved in platelet aggregation, and the association of bleeding and SSRI use was suggested two decades ago. In the last few years, some reviews have confirmed that initial fear. In contrast with aspirin, SSRIs seem to be related to non-ulcer, non-variceal gastrointestinal bleeds. SSRIs are usually associated with upper gastrointestinal bleeding but there is surprisingly little literature on lower gastrointestinal bleeding (LGIB) …

Interactions Between Antiepileptics And Second-Generation Antipsychotics, Jose De Leon, Vincenza Santoro, Concetta D'Arrigo, Edoardo Spina

Psychiatry Faculty Publications

INTRODUCTION: Pharmacokinetic and pharmacodynamic drug interactions (DIs) can occur between antiepileptics (AEDs) and second-generation antipsychotics (SGAPs). Some AED and SGAP pharmacodynamic mechanisms are poorly understood. AED-SGAP combinations are used for treating comorbid illnesses or increasing efficacy, particularly in bipolar disorder.

AREAS COVERED: This article provides a comprehensive review of the interactions between antiepileptics and second-generation antipsychotics. The authors cover pharmacokinetic AED-SGAP DI studies, the newest drug pharmacokinetics in addition to the limited pharmacodynamic DI studies.

EXPERT OPINION: Dosing correction factors and measuring SGAP levels can help to compensate for the inductive properties of carbamazepine, phenytoin, phenobarbital and primidone. Further studies …

Perceived Health In Lung Cancer Patients: The Role Of Positive And Negative Affect, Jameson K. Hirsch, Andrea R. Floyd, Paul R. Duberstein

ETSU Faculty Works

Purpose: To examine the association of affective experience and health-related quality of life in lung cancer patients, we hypothesized that negative affect would be positively, and positive affect would be negatively, associated with perceived health.

Methods: A sample of 133 English-speaking lung cancer patients (33% female; mean age = 63.68 years old, SD = 9.37) completed a battery of self-report surveys.

Results: Results of our secondary analysis indicate that trait negative affect was significantly associated with poor physical and social functioning, greater role limitations due to emotional problems, greater bodily pain, and poor general health. Positive affect was significantly associated …

Risk Factors For Depression Among Married Women Belonging To Higher And Lower Socioeconomic Status In Karachi, Pakistan, Saima Zainab, Zafar Fatmi, Ambreen Kazi

Community Health Sciences

OBJECTIVES: To determine the risk factors for depression among married women belonging to low and high socioeconomic status in Karachi.METHODS: The study design was cross-sectional. The data was collected from 128 adult married women during July to September 2005. The women were selected from different socioeconomic classes from five hospitals/institutes in Karachi. The Centre for Epidemiology Studies-Depression (CES-D) scale was used to screen the subjects for depression and a structured questionnaire was used to identify the factors for depression.RESULT: According to the CES-D scale, 65% of the study population was found to be depressed. Among the women from high socioeconomic …

A Community-Integrated Home Based Depression Intervention For Older African Americans: Descripton Of The Beat The Blues Randomized Trial And Intervention Costs., Laura N Gitlin, Lynn Fields Harris, Megan Mccoy, Nancy L Chernett, Eric Jutkowitz, Laura T Pizzi

Center for Applied Research on Aging and Health Research Papers

ABSTRACT: BACKGROUND: Primary care is the principle setting for depression treatment; yet many older African Americans in the United States fail to report depressive symptoms or receive the recommended standard of care. Older African Americans are at high risk for depression due to elevated rates of chronic illness, disability and socioeconomic distress. There is an urgent need to develop and test new depression treatments that resonate with minority populations that are hard-to-reach and underserved and to evaluate their cost and cost-effectiveness. METHODS/DESIGN: Beat the Blues (BTB) is a single-blind parallel randomized trial to assess efficacy of a non-pharmacological intervention to …

Psychosis In Indigenous Populations Of Cape York And The Torres Strait, Ernest M. Hunter, Bruce D. Gynther, Carrick J. Anderson, Leigh-Ann L. Onnis, Jeffrey R. Nelson, Wayne Hall, Bernhard T. Baune, Aaron R. Groves

Aboriginal Policy Research Consortium International (APRCi)

Objective: To describe and characterise treated psychotic disorders in the Indigenous populations of Cape York and the Torres Strait.

Design: Cross-sectional analysis of patients with a psychotic disorder identified by treating psychiatrists.

Setting and participants: Indigenous patients aged 􏰀 15 years in Cape York and Torres Strait communities receiving treatment for a psychotic disorder over 3 months in 2010.

Main outcome measures: Prevalence of psychosis diagnoses, intellectual disability, and substance use comorbidities.

Results: 171 patients were included. The prevalence rate in this population was 1.68%, higher for males (2.60%) than females (0.89%), and twice as high in the Aboriginal (2.05%) …

Medical Evaluation And Triage Of The Agitated Patient: Consensus Statement Of The American Association For Emergency Psychiatry Project Beta Medical Evaluation Workgroup, Kimberly Nordstrom, Leslie S. Zun, Michael P. Wilson, Victor Stiebel, Anthony T. Ng, Benjamin Bregman, Eric L. Anderson

Psychiatry and Behavioral Sciences Faculty Publications

Numerous medical and psychiatric conditions can cause agitation, some of these causes are life threatening. It is important to be able to differentiate between medical and non-medical causes of agitation so that patients can receive appropriate and timely treatment. This article aims to educate all clinicians in non-medical settings, such as mental health clinics, and medical settings on the differing levels of severity in agitation, basic triage, use of de-escalation, and factors, symptoms, and signs in determining whether a medical etiology is likely. Lastly, this article focuses on the medical workup of agitation when a medical etiology is suspected or …

Discerning Reported Suicide Attempts Within A Youthful Offender Population, Christopher A. Mallett, Leaanne Derigne, Linda M. Quinn, Patricia A. Stoddard Dare

Social Work Faculty Publications

With suicide being the third leading cause of death among young people, early identification of risk is critical, particularly for those involved with the juvenile courts. In this study of court-involved youth (N = 433) in two Midwest counties, logistic regression analysis identified some expected and unexpected findings of important demographic, educational, mental health, child welfare, and juvenile court-related variables that were linked to reported suicide attempts. Some of the expected suicide attempt risk factors for these youth included prior psychiatric hospitalization and related mental health services, residential placement, and diagnoses of depression and alcohol dependence. However, the most unexpected …

Preventing Mental Distress In The Military, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon D. Elhaid, J. Donald Richardson

RDC@Western Research Highlights

No abstract provided.

Preventing Mental Distress In The Military, Charles Nelson, Kate St. Cyr, Bradley Corbett, Elisa Hurley, Shannon Gifford, Jon D. Elhai, J. Donald Richardson

CRDCN Research Highlight/RCCDR en évidence

No abstract provided.

Body Dissatisfaction: Commitment, Support And Trust In Romantic Relationships, Lilia Juarez, Mary Pritchard

Psychological Sciences Faculty Publications and Presentations

Research investigating dimensions of relationship quality (Markey, Markey, & Birch, 2001; Pierce, Sarason, & Sarason, 1996) has suggested that aspects of relationship quality (e.g., commitment, support, trust) are related to lower levels of body dissatisfaction in women. However no studies have examined the effect of all three measures of relationship quality on body dissatisfaction simultaneously. Trust and support correlated with body dissatisfaction in men and women. Additionally the results showed that lack of support is a predictor of body dissatisfaction in men, lack of trust is a predictor in women; relationship commitment did not appear to relate to body dissatisfaction.

Vitamin D: Does It Play A Role In Psychiatry, Mukesh Mohan Bhimani

Department of Psychiatry

No abstract provided.

Psychosis And Smoking Cessation: Difficulties In Quitting Associated With Sex And Substance Abuse, Ana González-Pinto, Susana Alberich, Sonia Ruiz De Azúa, Mónica Martínez-Cengotitabengoa, Miryan Fernández, Miguel Gutiérrez, Margarita Saenz, Ariadna Besga, Paloma Galdós, Jose De Leon

Psychiatry Faculty Publications

No prospective studies of first psychotic episodes have explored sex differences in smoking cessation. The aim of this study was to determine the influence of sex and substance abuse on smoking cessation during an 8-year follow-up of patients after a first psychotic episode. Logistic regression modeling was used to identify factors associated with smoking cessation by sex. To examine for sex variable interactions, the following two methods were used: 1) for other clinical variables, mixed analyses were calculated; and 2) for use of other substances, logistic regression models were performed only in the substance users. At baseline, 79% of men …

Can The Holmes-Rahe Social Readjustment Rating Scale (Srrs) Be Used As A Suicide Risk Scale? An Exploratory Study, Hilario Blasco-Fontecilla, David Delgado-Gomez, Teresa Legido-Gil, Jose De Leon, M. Mercedes Perez-Rodriguez, Enrique Baca-Garcia

Psychiatry Faculty Publications

The objective of this research was to examine whether the Holmes-Rahe Social Readjustment Rating Scale, a life event scale, can be used to identify suicide attempters. The Holmes-Rahe Social Readjustment Rating Scale's ability to identify suicide attempters was tested in 1183 subjects (478 suicide attempters, 197 psychiatric inpatients, and 508 healthy controls) using the Fisher Linear Discriminant Analysis and traditional psychometric methods. The Fisher Linear Discriminant Analysis outperformed traditional psychometric approaches (area under the curve: 0.85 vs. 0.78; p < 0.05) and indicated that this scale may be used to identify suicide attempters. The life events that better characterized suicide attempters were change in frequency of arguments, marital separation, and personal injury. The Holmes-Rahe Social Readjustment Rating Scale may help identify suicide attempters.

The Social Production Of Substance Abuse And Hiv/Hcv Risk: An Exploratory Study Of Opioid-Using Immigrants From The Former Soviet Union Living In New York City, Honoria Guarino, Sarah K. Moore, Lisa A. Marsch, Sal Florio

Dartmouth Scholarship

Several former Soviet countries have witnessed the rapid emergence of major epidemics of injection drug use (IDU) and associated HIV/HCV, suggesting that immigrants from the former Soviet Union (FSU) may be at heightened risk for similar problems. This exploratory study examines substance use patterns among the understudied population of opioid-using FSU immigrants in the U.S., as well as social contextual factors that may increase these immigrants' susceptibility to opioid abuse and HIV/HCV infection. In-depth interviews were conducted with 10 FSU immigrants living in New York City who initiated opioid use in adolescence or young adulthood, and with 6 drug treatment …

Resemblance Of Symptoms For Major Depression Assessed At Interview Versus From Hospital Record Review, Ying Chen, Haimin Li, Yihan Li, Dong Xie, Zhiyang Wang, Fuzhong Wang, Yuan Shen, Sulin Ni, Yan Wei, Yanhua Liu, Lanfen Liu, Chengge Gao, Jun Liu, Lijuan Yan, Gang Wang, Keqing Li, Qiang He, Tiehang Liu, Jinbei Zhang, Yan Ren, Qunli Du, Jing Tian, Honghui Chen, Yanfang Luo, Fengzhi Zhang, Guangwei Sun, Chunjie Shan, Xueyi Wang, Yutang Zhang, Xiaoqin Weng, Yunchun Chen, Zhen Kang, Jing Guan, Yiping Chen, Shenxun Shi, Kenneth S. Kendler, Jonathan Flint, Hong Deng

Psychiatry Publications

Background

Diagnostic information for psychiatric research often depends on both clinical interviews and medical records. Although discrepancies between these two sources are well known, there have been few studies into the degree and origins of inconsistencies.

Principal findings

We compared data from structured interviews and medical records on 1,970 Han Chinese women with recurrent DSM-IV major depression (MD). Correlations were high for age at onset of MD (0.93) and number of episodes (0.70), intermediate for family history (+0.62) and duration of longest episode (+0.43) and variable but generally more modest for individual depressive symptoms (mean kappa = 0.32). Four factors …

Comparison Of Statistical Tests For Association Between Rare Variants And Binary Traits, Silviu-Alin Bacanu, Matthew R. Nelson, John C. Whittaker

Psychiatry Publications

Genome-wide association studies have found thousands of common genetic variants associated with a wide variety of diseases and other complex traits. However, a large portion of the predicted genetic contribution to many traits remains unknown. One plausible explanation is that some of the missing variation is due to the effects of rare variants. Nonetheless, the statistical analysis of rare variants is challenging. A commonly used method is to contrast, within the same region (gene), the frequency of minor alleles at rare variants between cases and controls. However, this strategy is most useful under the assumption that the tested variants have …

Network-Assisted Investigation Of Combined Causal Signals From Genome-Wide Association Studies In Schizophrenia, Peilin Jia, Lily Wang, Ayman H. Fanous, Carlos N. Pato, Todd L. Edwards, Zhongming Zhao

Psychiatry Publications

With the recent success of genome-wide association studies (GWAS), a wealth of association data has been accomplished for more than 200 complex diseases/traits, proposing a strong demand for data integration and interpretation. A combinatory analysis of multiple GWAS datasets, or an integrative analysis of GWAS data and other high-throughput data, has been particularly promising. In this study, we proposed an integrative analysis framework of multiple GWAS datasets by overlaying association signals onto the protein-protein interaction network, and demonstrated it using schizophrenia datasets. Building on a dense module search algorithm, we first searched for significantly enriched subnetworks for schizophrenia in each …

The Impact Of A Naturalistic Stressor On Spontaneous Alternation Behavior: A New Animal Model Of Ocd, Christina Finch

Behavioral Neuroscience Honors Papers

Over the past few decades, various animal models of obsessive compulsive disorder (OCD) have been developed. Similarly, various stressors have been used throughout animal research. The Spontaneous Alternation Behavioral (SAB) model is a well-established model of OCD while 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) has recently become a popular naturalistic stressor. This study linked the two together, thus modeling the effect of stress on OCD behaviors. After living in an enriched or standard environment for 3 weeks, male Sprague-Dawley rats were exposed to either TMT or no odor, and then were examined in the SAB task. Unlike what was hypothesized, the enriched environment proved …

Improved Self-Control Associated With Using Relatively Large Amounts Of Glucose: Learning Self-Control Is Metabolically Expensive, Matthew T. Gailliot

Faculty Publications

The current study examined whether changes in glucose during a self-control task would predict changes in self-control performance later on. Participants attended two experimental sessions, spaced two weeks apart. During each session, they had their glucose measured, completed the Stroop task as a measure of self-control, and then had their glucose measured again. Larger decreases in glucose (from before to after the Stroop task) during the first session predicted larger increases in improvement on the Stroop task during the second session, in the form of increased speed. Learning self-control might benefit from using larger amounts of glucose. Learning self-control is …

Mortality Salience And Metabolism: Glucose Drinks Reduce Worldview Defense Caused By Mortality Salience, Matthew T. Gailliot

Faculty Publications

The current work tested the hypothesis that a glucose drink would reduce worldview defense following mortality salience. Participants consumed either a glucose drink or placebo, wrote about either death or dental pain, and then completed a measure of worldview defense (viewing positively someone with pro-US views and viewing negatively someone with anti-US views). Mortality salience increased world- view defense among participants who consumed a placebo but not among participants who consumed a glucose drink. Glucose might reduce defensiveness after mortality salience by increasing the effectiveness of the self-controlled suppression of death-related thought, by providing resources to cope with mortality salience …

Breaking The Rules: Low Trait Or State Self-Control Increases Social Norm Violations, Matthew T. Gailliot, Seth A. Gitter, Michael D. Baker, Roy F. Baumeister

Faculty Publications

Two pilot and six studies indicated that poor self-control causes people to violate social norms and rules that are effortful to follow. Lower trait self-control was associated with a greater willingness to take ethical risks and use curse words. Participants who completed an initial self-control task that reduced the capacity for self-control used more curse words and were more willing to take ethical risks than participants who completed a neutral task. Poor self-control was also associated with violating explicit rules given by the experimenter. Depleting self-control resources in a self-control exercise caused participants subsequently to talk when they had been …

Variants Located Upstream Of Chrnb4 On Chromosome 15q25.1 Are Associated With Age At Onset Of Daily Smoking And Habitual Smoking, Manav Kapoor, Jen-Chyong Wang, Sarah Bertelsen, Kathy Bucholz, John P. Budde, Anthony Hinrichs, Arpana Agrawal, Andrew Brooks, David Chorlian, Danielle Dick, Victor Hesselbrock, Tatiana Foroud, John Kramer, Sammuel Kuperman, Niklas Manz, John Numberger Jr, Bernice Porjesz, John Rice, Jay Tischfield, Xiaoling Xuei, Marc Schuckit, Haward J. Edenberg, Laura J. Bierut, Alison M. Goate

Psychiatry Publications

Several genome-wide association and candidate gene studies have linked chromosome 15q24–q25.1 (a region including the CHRNA5-CHRNA3-CHRNB4 gene cluster) with alcohol dependence, nicotine dependence and smoking-related illnesses such as lung cancer and chronic obstructive pulmonary disease. To further examine the impact of these genes on the development of substance use disorders, we tested whether variants within and flanking theCHRNA5-CHRNA3-CHRNB4 gene cluster affect the transition to daily smoking (individuals who smoked cigarettes 4 or more days per week) in a cross sectional sample of adolescents and young adults from the COGA (Collaborative Study of the Genetics of Alcoholism) families. Subjects were …

Reintegration Of Child Soldiers In Burundi: A Tracer Study, Mark J.D. Jordans, Ivan H. Komproe, Wietse A. Tol, Aline Ndayisaba, Theodora Nisabwe, Brandon A. Kohrt

Psychiatry and Behavioral Sciences Faculty Publications

No abstract provided.

Anorexia Nervosa: Current Research From A Biological Perspective, Udy Tropp

The Science Journal of the Lander College of Arts and Sciences

Eating disorders are viewed as serious mental illnesses, carrying significant, life-threatening medical and psychiatric implications, including morbidity and mortality. According to the Academy of Eating Disorders, anorexia nervosa has the highest mortality rate of any psychiatric disorder. The American Psychiatric Association (2004) claims that approximately three percent of the United States female population has a clinically relevant eating disorder. Risk of premature death is 6-12 times higher in women with anorexia as compared to the general population, and it has become the third most common form of chronic illness among adolescent women aged 15 to 19 years. Although the prevalence …

Changing How Students Process And Comprehend Texts With Computer-Based Self-Explanation Training, Christopher A. Kurby, Joseph P. Magliano, Srikanth Dandotkar, James Woehrle, Sara Gilliam, Danielle S. Mcnamara

Faculty Research and Creative Activity

This study assessed whether and how self-explanation reading training, provided by iSTART (Interactive Strategy Training for Active Reading and Thinking), improves the effectiveness of comprehension processes. iSTART teaches students how to self-explain and which strategies will most effectively aid comprehension from moment-to-moment. We used RSAT (Reading Strategy Assessment Tool) to assess how iSTART changes the relation between important selfexplanation reading strategies—bridging and elaboration—and online comprehension, and how often they are produced. College and high school students received iSTART and were administered RSAT prior to and post-training. Results from three experiments showed that iSTART primarily benefits bridging inferences when self explaining. …

Stigma Of Mental Illness-1: Clinical Reflections, Amresh Srivastava

Data and Test Instruments

Stigma of Mental Illness-1: Clinical Reflections Amresh Shrivastava*, Megan Johnston**, Yves Bureau*** ABSTRACT Although the quality and effectiveness of mental health treatments and services have improved greatly over the past 50 years, therapeutic revolutions in psychiatry have not yet been able to reduce stigma. Stigma is a risk factor leading to negative mental health outcomes. It is responsible for treatment seeking delays and reduces the likelihood that a mentally ill patient will receive adequate care. It is evident that delay due to stigma can have devastating consequences. This review will discuss the causes and consequences of stigma related to mental …

Osmd: Cultural Competence Tool For Research, Education, And Practice, Rebecca Tadlock-Marlo, Danny Applegate

Faculty Research & Creative Activity

Results from a mixed methods study provide insight into redefining multicultural counseling competencies specific to school counselors. Foci include new counseling competencies and implications for counselor educators. Attendees will explore aspects of multiculturalism, counseling competencies of school counselors, research implications, and its importance for the field. Also discussed will be applying information to the development of skills, knowledge, and awareness of counselors-in-training through specific pedagogical examples. Participant discussion is vital to this presentation to further discuss content area, explore redefining multiculturalism, and implications this research has for both practicing counselors and counselor educators. Attendees can expect to gain groundbreaking theory …