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Biomechanical And Psychophysical Underpinnings Of Balance Dysfunction In Individuals With Traumatic Brain Injury, Naphtaly Ehrenberg

Dissertations

Falls are a major burden on healthcare infrastructure, especially in older adults and even more so in older individuals that are living in institutions. According to data from the Centers for Disease Control and Prevention (CDC), from 2010 to 2020, unintentional falls were the leading cause of nonfatal emergency department visits for all age groups except among individuals from 15-24 years of age, where unintentional falls ranked a very close second to being unintentionally struck by or against. Among older individuals living in the community, approximately 30-35% fall at least once in a given year, and around three times as …

A Clinical Practice Review Of Percutaneous Ethanol Injection For Thyroid Nodules: State Of The Art For Benign, Cystic Lesions, Robert D.E. Clark, Xinyi Luo, Peter P. Issa, Ralph P. Tufano, Emad Kandil

School of Medicine Faculty Publications

Percutaneous ethanol injection (PEI) is a widely used treatment option for cystic and predominantly cystic thyroid nodules. It has several advantages over other treatment modalities. Compared to surgery, PEI is less painful, can be performed in the outpatient setting, and carries less risk of transient or permanent side effects. Compared to other minimally invasive techniques such as radiofrequency ablation (RFA), PEI is less expensive and does not require specialized equipment. PEI performs well in the context of cystic nodules. PEI does not perform as well as other techniques in solid nodules, so its use as a primary treatment is limited …

Gpr75 Deficiency Attenuates High Fat Diet-Driven Obesity And Glucose Intolerance, Sakib Hossain

NYMC Student Theses and Dissertations

Recently, a collaboration between Regeneron Pharmaceuticals and the Schwartzman-Garcia labs at New York Medical College published an exome sequencing study of individuals across the United Kingdom, United States, and Mexico which concluded that individuals possessing non-functioning, truncated mutations to the orphan g protein coupled receptor (GPCR), GPR75, had lower BMI and 54% reduced likelihood of obesity. The present study was undertaken to fully characterize the metabolic phenotype of Gpr75 deficient mice when fed a high fat diet (HFD) and explore potential mechanisms by which GPR75 activation links to increased adiposity and decreased glucose tolerance. After 14 weeks of HFD-feeding we …

Does Caffeine Consumption Affect Work Performance Across Different Job Types?, Bryan Js Goh, Joshua Tan, Cleavon Chong, Sean Ker

Introduction to Research Methods RSCH 202

We propose executing a panel series case study for a large organization in Singapore over a year to examine how caffeine impacts work performance across different job types. Our research question is how does caffeine affect work performance under different conditions due to work type differences. Our dependent variable would be work performance as measured by employees’ Key Performance Indicators (KPIs). We propose to gather data for two of our important independent variables: caffeine use through a recorded pantry system and average sleep hours from a survey. We will analyze the data by using two-factor ANOVA with replication to find …

Social Creatures: The Impact Of Solitary Confinement On Psychophysiological Health And How Inmates Percieve Their Humanity And Social Well-Being, Julia Austin

Honors Projects

This paper will define and examine the use of solitary confinement within the United States prison system and review its mental, physical, and social impacts. As social creatures, human mental and physical well-being depends on meaningful social interactions absent in segregation units. As it currently stands, vulnerable populations, including racial minorities, LGBTQIA+ individuals, and those with developmental disabilities or psychological disorders, are at risk of irrevocable harm and abuse within these facilities from staff as well as other inmates. With a rotating 80,000 inmates held in solitary confinement every day, the current structure of the prison system deemphasizes rehabilitation and …

Effect Of Static Stretching On Agonists, Antagonists, And Agonist-Antagonist Combination On Total Training Volume, Diego Pessoa, Henrique Penfold, Sincler Pegado, Michel Gonçalves, Juliana Brandão Pinto De Castro, Jeffrey Willardson, Humberto Miranda

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 665-675, 2023. The purpose of this study was to examine the effects of static stretching (SS) of agonists and antagonists between sets on the total training volume (TTV) performed across multiple sets for the leg extension exercise. Twelve male subjects with experience in resistance training (RT) participated in this study. Subjects performed 10 repetition maximum (10RM) test and retest trials for the leg extension exercise. Four different protocols were randomly applied as follows: quadriceps stretching (AG); hamstrings stretching (AN); quadriceps and hamstrings stretching (AGN); and traditional control without stretching (TR). Significant differences (p≤0.05) were …

Cardiovascular Responses During Light-Intensity Aerobic Exercise With Varying Levels Of Limb Occlusion Pressures., William R. Vanwye, Alyssa M. Weatherholt, Lee J. Winchester, Johnny G. Owens, Micah Spears

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 676-687, 2023. The study aimed to assess cardiovascular responses to low-intensity aerobic exercise with varying levels of limb occlusion pressures (LOP) in a healthy population of men and women 30 to 60 years. The study was a single-session repeated measures design. Thirty individuals completed the study. All subjects participated in a single bout of low-intensity cycling (30-39% HRR) with bilateral lower extremity (LE) BFR for four 5-minute stages [0% (No BFR), 40%, 60%, and 80% LOP] with a 2-minute active rest between stages (BFR pressure released). The subjects’ systolic blood pressure (SBP), diastolic blood …

Effect Of Obesity And Insulin Resistance On Glucose And Fatty Acid Metabolism, Chao Cao

WUSM Theses and Dissertations – All Programs

In people with obesity, insulin resistance of glucose and fatty acid metabolism is common and it is thought that insulin resistance of fatty acid metabolism is involved in causing insulin resistance of glucose metabolism and subsequently hyperglycemia through a mechanism referred to as “lipotoxicity”. However, in many individuals with obesity and insulin resistance fasting plasma glucose and free fatty acid (FFA) concentrations are not elevated. It is widely believed that pancreatic beta-cells detect the need to increase insulin secretion in order to compensate for the impaired insulin action caused by insulin resistance in these people, whereas beta-cell dysfunction results in …

Eco-Interoception: What Plants, Fungi And Protista Have Taught My Body, Sara Riley Dotterer

Art Theses and Dissertations

To me, ecology is the relational, full-body awareness that I am made up of and deeply connected to everything around me; and for better or worse, this is reciprocal. I form ecotones, an ecological transitional zone between two ecosystems, with the world around me. I use this ecotonal lens to blur binaries and dissolve boundaries between me and the world “outside my body.” During my Masters of Fine Arts at Southern Methodist University, I have continuously explored and represented the lives of various more-than-human species outside of my body, including plants, fungi and protista through an ecotonal lens. Although these …

Comparing Calculated And Perceived Energy Needs In Collegiate Student-Athletes, Lyndsey T. Reed

Honors Theses

The purpose of this study was to evaluate NCAA student-athletes' level of knowledge related to their energy needs. The participants were 75—42 male and 33 female—NCAA Division I student-athletes enrolled at the University of Mississippi (UM) from a variety of sports. In-person data collection took place at UM Athletics facilities by sports registered dietitians during team talks. The names of the athletes were used to find their pre-existing calculated energy, resting metabolic rate (RMR) and total energy expenditure (TEE) using the Nelson equation and the appropriate activity factor. Questionnaire and RMR/TEE data were analyzed and compared to assess knowledge related …

Remote Physiological Monitoring Of The Giant Panda And Red Panda Using Near Infrared Spectroscopy And Machine Learning, Qingyu Sheng

Theses and Dissertations

Appropriate conservation decisions and efforts must be based on real−time and accurate information about wildlife populations. However, it is extremely challenging to monitor the population demography and physiological traits of many threatened and secretive animal species through direct observation and capture. Near infrared spectroscopy (NIRS) has the potential to be a remote tool to address questions concerning wildlife physiology and demography by analyzing “signs” of animals without seeing or capturing them. In this dissertation, two species, the giant panda (Ailuropoda melanoleuca) and red panda (Ailurus fulgens) are used as a case study, to demonstrate NIRS’ feasibility …

Understanding Context Dependent Responses To Climate Change In Arizona Tiger Salamanders (Ambystoma Mavortium Nebulosum), Kentrell Richardson

Masters Theses, 2020-current

Future emissions scenarios project climate change to increase average global temperatures by at least two ℃ in the next 50 years resulting in changes in local climate and causing increased variability within microclimates. Ectotherms are especially sensitive to climate change due to their dependence on environmental temperatures to regulate physiological functions. Changes in temperature are likely to impact thermally cued processes within amphibians and result in changes in variable magnitudes and directions within local populations.

Salamanders were placed in cups and partially submerged in a water bath and heated at a rate of ~0.27℃/ minute. Once salamanders were unable to …

Du Undergraduate Showcase: Research, Scholarship, And Creative Works, Caitlyn Aldersea, Justin Bravo, Sam Allen, Anna Block, Connor Block, Emma Buechler, Maria De Los Angeles Bustillos, Arianna Carlson, William Christensen, Olivia Kachulis, Noah Craver, Kate Dillon, Muskan Fatima, Angel Fernandes, Emma Finch, Colleen Cassidy, Amy Fishman, Andrea Francis, Stacia Fritz, Simran Gill, Emma Gries, Rylie Hansen, Shannon Powers, Jacqueline Martinez, Zachary Harker, Ashley Hasty, Mykaela Tanino-Springsteen, Kathleen Hopps, Adelaide Kerenick, Colin Kleckner, Ci Koehring, Elijah Kruger, Braden Krumholz, Maddie Leake, Lyneé Alves, Seraphina Loukas, Yatzari Lozano Vazquez, Haley Maki, Emily Martinez, Sierra Mckinney, Audrey Mitchell, Kipling Newman, Audrey Ng, Megan Lucyshyn, Andrew Nguyen, Stevie Ostman, Casandra Pearson, Alexandra Penney, Julia Gielczynski, Tyler Ball, Anna Rini, Christina Rorres, Simon Ruland, Helayna Schafer, Emma Sellers, Sarah Schuller, Claire Shaver, Kevin Summers, Isabella Shaw, Madison Sinar, Claudia Pena, Apshara Siwakoti, Carter Sorensen, Madi Sousa, Anna Sparling, Alexandra Revier, Brandon Thierry, Dylan Tyree, Maggie Williams, Lauren Wols

DU Undergraduate Research Journal Archive

DU Undergraduate Showcase: Research, Scholarship, and Creative Works

The Effects Of Acute Exercise On Memory: Considerations Of The Testing Effect, Philip Christian

Honors Theses

This study had three main objectives. The first objective was to determine whether or not there was evidence of a testing effect being present when a short-term memory assessment is included along with a long-term memory assessment. The second objective was to determine whether acute exercise can improve long-term memory recall over a control condition. The third objective was to determine if the potential effects of acute exercise on long-term memory are confounded by the inclusion of a short-term memory assessment. Participants were 54 undergraduate students at the University of Mississippi, with an age range of 18-22 years old. Participants …

An Argument For The Utilization Of Amphibian Stress As An Indicator Of Wetland Condition, Andrew W. Sisson

Honors College Theses

Traditional forms of rapid wetland condition assessments focus on foliage health, nutrient enrichment, chemical contamination, and surrounding land usage, often overlooking an evaluation of the animals living in the wetland. More intense assessments include the National Wetland Condition Assessment (NWCA) and indices of biotic integrity, which focus on community composition (e.g., diversity and species richness) and abundances. These indices require expertise in species identification and do not provide information about the animal’s fitness. Animal stress physiology, which generally correlates with measures used to quantify animal fitness (e.g., survival, reproduction, and body condition), may provide a complementary rapid assessment method aimed …

Monitoring Training Loads In Judo Athletes: Different Time Courses Of Physiological, Neuromuscular, And Perceptual Responses., Bruno Campos, Fabio Nakamura, Eduardo Macedo Penna, Renato Moraes, João Gabriel Da Silveira Rodrigues, Maicon Rodrigues Albuquerque, Luciano S. Prado

International Journal of Exercise Science

International Journal of Exercise Science 16(6): 638-653, 2023. This study aims to elucidate the internal load, performance, physiological, and perceptual recovery responses during four weeks of traditional judo training. Ten cadet and junior judo athletes were evaluated daily for four weeks, in which their perception of recovery, heart rate variability, handgrip strength, and countermovement jump performance were assessed. A one-way repeated-measures ANOVA was performed to analyze the variables across the weeks. A significant time effect in internal load (F = 6.51; p = 0.001) has been observed. Handgrip test performance showed significantly higher values in the 3rd and 4th weeks …

Reliability Of Time To Exhaustion Above The Power Output At Vo2peak In Trained Mountain Bikers, Allan Inoue, Eduardo Lattari, Everton Carmo, Bruno Oliveira, Elirez Silva, Tony Santos

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 654-664, 2023. To our knowledge, no study has investigated the reliability of the time to exhaustion (TTE) test during constant-load trials in Olympic distance cross-country mountain bike (XCO-MTB) athletes. Thus, the aim was to analyze the reliability of the TTE test at intensities above peak oxygen uptake (VO_2peak) in trained XCO-MTB athletes. Fifteen male XCO-MTB athletes (mean ± SD: age 31.5 ± 6.6 years, stature 174.0 ± 5.4 cm, body mass 67.2 ± 5.1 kg, VO_2peak 64.5 ± 4.7 mL∙kg^-1∙min^-1) completed 2 TTE tests on the cycle …

Multichannel Modulation Of Depolarizing And Repolarizing Ion Currents Increases The Positive Rate-Dependent Action Potential Prolongation, Candido Cabo

Publications and Research

Prolongation of the action potential duration (APD) could prevent reentrant arrhythmias if prolongation occurs at the fast excitation rates of tachycardia with minimal prolongation at slow excitation rates (i.e., if prolongation is positive rate-dependent). APD prolongation by current anti-arrhythmic agents is either reverse (larger APD prolongation at slow rates than at fast rates) or neutral (similar APD prolongation at slow and fast rates), which may not result in an effective anti-arrhythmic action. In this report we show that, in computer models of the human ventricular action potential, the combined modulation of both depolarizing and repolarizing ion currents results in a …

Heart Rate Response And Locomotor Activity Of Female Skateboarders, Bipoc Skateboarders, And Non-Skateboard Users During A Typical Session At A Community Skatepark, Jeff A. Nessler, Alivia L. Lundquist, Natalie Casas Jimenez, Sean C. Newcomer

International Journal of Exercise Science

International Journal of Exercise Science 16(7): 599-612, 2023. Prior research has demonstrated that male adults and youth engaged in skateboarding at community skateparks achieve heart rates that meet or exceed recommendations for exercise by the CDC. However, these studies do not adequately evaluate other non-traditional or ethnically diverse users who may differ in how they utilize the skatepark and in their cardiovascular response. The purpose of this experiment was to measure heart rate response and locomotor movement in three lesser studied groups that frequently utilize community skateparks, and to compare these results with those reported previously in male adult and …

Effect Of High Intensity Interval Training Under Mask On Force Vital Capacity In Football Players, Neranoch Bumrung, Apiwan Manimmanakorn, Natthapon Traiperm

International Journal of Exercise Science

International Journal of Exercise Science 16(6): 576-586, 2023. The purpose of the study was to investigate the effect of high interval training (HIIT) under mask on forced vital capacity in football players. Fourteen male football players (age 20 ± 2 years) were randomized into the without mask group (CON) or with the 2 difference mask groups [Surgical mask (SM), FFP2 mask (FM)]. HIIT program were implemented six movements in each session three times per week. Body composition, forced vital capacity and percutaneous oxygen saturation test were taken before and after 4 weeks intervention. The results show that forced vital capacity …

Muscle Thickness, Echo-Intensity, Peak Force, Time Under Tension, Total Load Lifted, And Perception Of Effort Comparisons Between Two Abdominal Crunch Resistance Training Protocols In Recreationally-Trained Participants, Keanna Sullivan, Paula R. Ferreira, Vincent G.F. Martinez, Paulo Henrique Marchetti

International Journal of Exercise Science

International Journal of Exercise Science 16(6): 538-549, 2023. The primary purpose of this study was to evaluate acute dose response of different intensities with total volume equalized during the abdominal crunch exercise on muscle thickness, echo-intensity, peak force, time under tension, total load lifted, and perception of effort in recreationally-trained participants. Fifteen resistance-trained participants (23 ± 3 years) performed the abdominal crunch exercise in one of two different resistance training (RT) protocols in a randomized order: RT_4x10RM (4 sets of 10RM / 1-min rest) or RT_1x40RM (1 set of 40RM). Muscle thickness (MT), echo- intensity (EI), peak force …

Comparison Of A Ramp Cycle Ergometer And A Staged Assault Fitness Assaultbike Protocol For The Assessment Of Vo2max, Regis C. Pearson, Sara A. Garcia, Nathan T. Jenkins

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 613-619, 2023. We propose a new VO2max test using a progressive staged protocol on an Assault Fitness AssaultBike. Twelve healthy males performed a traditional ramp cycle ergometer test (TRAD) and a progressively staged AssaultBike protocol (AB) in a counterbalanced order. AB elicited higher immediate post-exercise lactate, absolute and relative VO2max, and maximum heart rate than TRAD (P = 0.006, P = 0.014, P = 0.007, and P = 0.001, respectively). The protocol outlined herein may provide a more accurate assessment of VO2max due to greater skeletal muscle mass recruitment that is more representative …

The Relationship Between Muscular Strength, Jump Power, And Bone Health In Collegiate Distance Runners, Daisy E. Huerta, Jarred M. Norris, William P. Mccormack, Todd C. Shoepe, Hawley C. Almstedt

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 563-575, 2023. Participation in sports, especially those involving impact loading, enhance bone mineral content (BMC) and density (BMD). Additionally, participation in impact loading sports may strengthen relationships between strength or power and bone variables. The purpose of this investigation was to examine relationships between measures of muscular performance and bone variables in Division I endurance athletes (29 males, 31 females, 19.6 ± 1.4 years). Dual-energy x-ray absorptiometry (DXA) scans were analyzed at the anterior-posterior (AP) and lateral (LAT) spine, femoral neck (FN), total hip (TH), whole body (WB), and ultra-distal forearm (UD) for BMC …

Can 5-Weeks Of Hypopressive Exercise Influence Sagittal Lumbo-Pelvic Position In Athletic And Non-Athletic Females?, Kimberly Assumpção Wojcik, Lucas Teixeira Pinheiro Machado, Carla Itatiana Bastos De Brito1, Tamara Rial Rebullido

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 550-562, 2023. Hypopressive exercises (HE) are part of the Low Pressure Fitness training program which is widely used by physical therapists in the rehabilitation of the pelvic floor, abdominal and spinal musculature. The aim of this study was to compare the effects of HE on the sagittal lumbo-pelvic posture in athletic and non-athletic females. It was hypothesized that a 5-week training program of HE could influence lumbo-pelvic position while reducing abdominal circumference and low back pain in athletic and non-athletic females. Twenty normoweight females (mean age = 24.8 (SD 3.5) years; body mass index …

Older Adult Aerobic Capacity, Muscular Strength, Fitness And Body Composition After 20+ Years Of Exercise Training: A Systematic Review And Meta-Analysis, Eric Leslie, Vincent Luna, Ann L. Gibson

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 620-637, 2023. Older adults (³ 65 years) are recommended to participate in regular exercise to maintain health in late adulthood. The impact of long-term (20+ years) exercise training that align with the American College of Sports Medicine’s (ACSM) recommended guidelines has not been evaluated for older adults. To address this, a systematic review and meta-analyses were performed regarding the effects of long-term exercise training on older adult aerobic capacity, muscular fitness, and body composition that meet the ACSM’s recommendation for weekly training volume. Ten studies with individuals that performed cardiorespiratory or resistance exercise met …

Immediate Effect Of Gluteus Medius Kinesio-Taping On Plantar Pressure Distribution And Balance Among Healthy Individuals, Deepa Shekar, Hemant K. Kalyan, Prem Venkatesan, Nithin Prakash, Karvannan Harikesavan

International Journal of Exercise Science

International Journal of Exercise Science 16(1): 587-598, 2023. Gluteus medius eccentrically regulates hip adduction and internal rotation in unilateral postures against gravity. Any weakness to Gluteus medius can lead to poor posture, impaired balance and altered plantar pressure. There is a scarcity of literature to find the immediate effect of gluteus medius kinesio-taping on plantar pressure distribution and balance among healthy individuals. A Randomized cross-over trial was conducted in outpatient physiotherapy department of Manipal Hospitals Bangalore, on 28 healthy individuals from March 2021 to April 2022. The taping was done on the dominant leg of the subjects, with no tape, …

Low-Load X High-Load Resistance Exercise: Greater Cell Swelling After A Training Session, Gabriel Agentilho, Erick Lucena, Luis Felipe M. Teixeira, Vanessa Boas, Isadora Ribeiro, Renato Barroso, Brad Schoenfeld, Marco Uchida

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 513-524, 2023. Cell swelling caused by resistance training is proposed to provide an anabolic stimulus for muscle growth and it is believed that these effects are heightened with the use of low loads. The purpose of this study was to compare the acute effects of two volume-equated resistance training (RT) protocols, low-load (LL) versus high-load (HL), on elbow flexor muscles thickness, arm circumference, and blood lactate concentration in well-trained individuals. Eight resistance-trained males performed the following two RT protocols involving unilateral elbow flexion of the dominant arm: i) LL, four sets with 50% 1 …

Entropy Of Heart Rate On Self-Selected Interval Exercises In Older Women, Lucas E. R. Santos, Karla K. Dames, Edilaine S. D. De Oiliveira, Matheus S. S. Fernades, Tayrine O. Filgueira, Bruna M. S. Mesquita, Catarina F. C. X. M. De Souza, Eduardo Lattari, Tony M. Santos

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 525-537, 2023. Non-linear analyzes such as Approximated Entropy (ApEn) and Sample Entropy (SampEn) could show the adaptability of the autonomic nervous system in relation to the dynamic changes caused by exercise. The aims of the study were: a) Investigate the effects of different Self-Selected based Interval Exercises (SSIE) configurations on Heart Rate (HR) entropy; b) Determine whether the stimuli time promote different entropy responses; c) Observe whether exercises with passive self-selected recovery time (SSRT) promote different HR entropy responses compared to those with imposed time and active recovery; and d) Determine whether post-training entropy …

Does Vdac2 Have A Bh3 Domain?, Lillian Ferkany

Honors Theses

Mitochondrial outer membrane permeabilization (MOMP) by Bax oligomerization triggers apoptosis. BCl-2 family proteins, classified as BH3 only proteins, pro-survival proteins, or pro-apoptotic proteins, control apoptosis partly through their agonist or antagonistic effects on Bax, which are mediated by their conserved BH3 domains. All BH3 domains form an alpha helix containing 5-7 conserved hydrophobic residues, designated H0-H5, and one conserved aspartic acid that drive interaction with Bax and other ‘multi-domain’ BCl-2 members. BH3 agonists induce Bax oligomerization, while BH3 antagonists sequester Bax to prevent MOMP. We discovered that voltage dependent anion channels (VDACs) in the MOM contain a putative BH3-like domain …

Pno-Monia, Ayati Lala, Nandana Varma

Human Diseases Graphic Novels

No abstract provided.