Digital Commons Network^™

The Edge-Distinguishing Game, Nathaniel Benjamin, Elisa Benthem, Cooper Burkel, Marissa E. Chesser, Mike Janssen

Communications on Number Theory and Combinatorial Theory

In this paper, we introduce a graph coloring game called the Edge-Distinguishing Game (EDGe). The edge-distinguishing chromatic number of a graph is used to determine the moves each player can make. We determine which player has a winning strategy for particular graphs and graph families. Additionally, utilizing principles from game theory as well as previous work on a computational solution for the Game of Cycles.

Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati

Karbala International Journal of Modern Science

Cancer is characterized by dysregulated metabolic signaling pathways, leading to uncontrolled cellular proliferation. Current cancer treatments, which involve surgery, radiotherapy, and chemotherapy, still cause adverse systemic toxicities. Accordingly, one possible effort that can be undertaken is to explore safe anticancer substances from protein sources such as peptides. Bioactive peptides can be isolated by hydrolyzing cowpea (Vigna unguiculata L. Walp) protein with trypsin. The objectives of this study were to isolate and fractionate bioactive peptides from cowpea, to determine the anticancer activity of peptide fractions, to identify active peptide fractions as anticancer agents using Liquid Chromatography High Resolution Mass Spectrometry …

Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta

Karbala International Journal of Modern Science

It has previously been shown that exogenous bacterial ribosomes added to somatic cells and various cancer cell lines generate ribosome-induced cell clusters (RICs) capable of transdifferentiating into multiple cellular lineages. However, the scope of ribosome-induced transdifferentiation in cancer cells remains poorly understood. This study aimed to analyze the effects of exogenous ribosome incorporation on human cancer cell lines, specifically the intestinal epithelial cell line Caco-2 and the hepatocellular carcinoma cell line HepG2. Caco-2 and HepG2 cells were cultured with purified bacterial ribosomes in human ES/iPS cell medium after trypsinization, resulting in the formation of ribosome-induced Caco-2 (RICs-Ca) and HepG2 (RICs-He) …

Selenoprotein P And Selenium As Potential Diagnostic Biomarkers For Breast Cancer Patients, Farah A. Rashid, Rawaa A. Ali, Hanaa A. Ali

Karbala International Journal of Modern Science

Breast cancer incidence increases in last decade. Oxidative stress increases during cancer development causes consuming of antioxidants. Selenium and its transporting protein, selenoprotein P have an important role in redox homeostasis. This study aims to investigate whether or not selenium and selenoprotein P could be diagnostic biomarkers for breast cancer patients. This study was included 30 individuals in control group who is age- and BMI-matched with 60 breast cancer patients. Selenium was measured by colorimetric assay kit and selenoprotein P was determined by Sandwich ELISA kits. The results indicate significant decrease (p < 0.0001) of serum selenium and selenoprotein P in breast cancer patients compared to control. A positive significant correlation (r = 0.6214, p < 0.0001) was found between selenium and selenoprotein P in breast cancer patients. Selenium has an excellent diagnostic accuracy with area under curve 0.9831, sensitivity 95% and specificity 100% at cut-off less than 3.54 mmol/L. Furthermore, selenoprotein P has also an excellent area under curve 0.9958 with sensitivity 96.77% and specificity 100% at cut-off less than 4.15 ng/ml. These exploratory findings appear that selenium and selenoprotein P could be potential diagnostic biomarkers for breast cancer patients. Further investigations in large-multicenter populations are needed to confirm results.

Mathematically Driven Enhancement In Information Security, Suhaib Badran, Asmaa Alqassab

Karbala International Journal of Modern Science

A new mathematically based cryptographic method has been proposed to improve information security; it involves transforming data into a matrix and performing bit-level operations. This decryption then follows the basic mechanism of a deterministic, fully invertible algorithm, with this invertible algorithm having the same principle as the existing ones: the process of decryption is symmetrical, where the process is reversed based on the input of the ciphertext. The plaintext is transformed into a square matrix, which includes matrix rotation, permutation of rows, circular bit shifting, and finally an affine linear transformation followed by an additional Base62-like encoding layer to further …

Tapping Into The Ocean’S Hidden Energy: Feasibility Of A 5 Mw Otec Installation In North Bali, Widodo Setiyo Pranowo, Yani Permanawati, Gisela Malya Asoka Anindita, Agung Kurniawan, Albertus Sulaiman, Johar Setiyadi, Safri Burhanuddin, Ivonne Milichristi Radjawane, Hansan Park, Endro Sigit Kurniawan

Karbala International Journal of Modern Science

Indonesia is an archipelagic country surrounded by water and faces energy challenges due to the low use of renewable energy. Among the potential renewable options, marine energy is a particularly suitable resource given the country’s geographical nature. Based on this discussion, seawater temperature can be used as an alternative ocean thermal en-ergy known as ocean thermal energy conversion (OTEC) by using the difference in sea surface and deep-sea water temperatures. Therefore, this study aimed to examine OTEC installations in North Bali waters using closed-cycle OTEC calculations for a 5 MW system. Following this objective, we examined the water conditions by …

Oregon State Rank Assessment For California Pinefoot (Pityopus Californicus), Lindsey K. Wise

Institute for Natural Resources Publications

Oregon state conservation status assessment for California Pinefoot (Pityopus californicus) using NatureServe methodology, 2026.

Assessment And Evidence Practices In Cybersecurity Education: A Systematic Review (2015–2025), James K. Mayberry

Journal of Cybersecurity Education, Research and Practice

This study presents a PRISMA-based systematic review of 412 cybersecurity education intervention studies, coding assessment methods, evidence types, claimed outcomes, use of established assessment instruments, and artifact availability. Despite frequent claims of skill development and workforce preparation, 45.4% of studies reported no identifiable assessment. Knowledge tests appeared in 11.4% of studies, while performance assessments appeared in 10.2%. From 2015 to 2025, assessment practices remained dominated by post-only designs or no assessment, with no statistically detectable increase in pre/post-capable designs. Use of established assessment instruments was rare, with 94.2% of assessed studies using ad hoc measures or not identifying an established …

Differentiating And Accommodating Ocd And Anxiety In Mathematical Contexts, Madeline F. Gavares

Interdivisional Studies Summer Fellows

Students in mathematics classrooms may experience emotional and cognitive challenges that affect how they engage with coursework and assessments. While math anxiety has been widely documented, less attention has been given to how obsessive-compulsive disorder (OCD), particularly checking behaviors, may influence students’ experiences in math settings. This study explores how students who report math anxiety and those who report OCD symptoms describe their engagement with math tasks and test-taking. Drawing on survey and interview data from students and teachers, this study examines how these experiences are articulated and perceived in academic math contexts, rather than evaluating ability or outcomes. By …

Surveying First-Year Stem Students’ Self-Reported Knowledge, Skills, And Attitudes Towards Teamwork, Gregory R. Goldsmith, Camilla Acosta

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The ability to work in a team is cited as a key outcome for many undergraduate Science, Technology, Engineering, and Mathematics (STEM) programs, both as a method for improving learning and as a highly desired trait for employers. Despite a growing focus on teamwork, our ability to design appropriate teamwork curriculum is limited by our poor understanding of what students arriving at university know about teamwork, what teamwork skills they consider themselves to possess, and their attitudes towards teamwork. We delivered a mixed-methods survey to first-year STEM undergraduate students (n = 205) to benchmark knowledge, skills and attitudes towards …

Coordinating Meaning With Ai System Cards: A Thematic Analysis, Jennifer Rene French Cyrek

Doctoral Dissertations and Projects

As the meaning of AI risk remains unsettled across sociotechnical and public discourse, AI system cards are an emergent, yet understudied, genre of technical documentation through which AI technology developers publicly frame new AI system capabilities including risks. This thematic content analysis study examines how AI technology developers coordinate meaning regarding risk and responsible development in stewardship of AI. Guided by a constitutive view of communication and systems theory, second-order cybernetics, and the cybernetic tradition, this study analyzes a purposive corpus of AI system cards collected from 2023-2025 using thematic content analysis and the hierarchy of meaning heuristic from coordinated …

Enhancing Ecological Resilience: Evaluating Peanut Island's Breakwater Impacts On Coral Reef And Shoreline Dynamics, Dayana Castillo

Electronic Theses and Dissertations

Anthropogenic shoreline modification and inlet-driven hydrodynamic processes can alter sediment transport pathways and sediment deposition in adjacent coral reef environments. This study evaluated how coastal engineering structures, sediment transport dynamics, and localized hydrodynamic processes influence sediment distribution and coral-associated habitats at Peanut Island, Florida. Beach profile surveys, shoreline mapping, sediment grain size analyses, coral monitoring, and historical aerial imagery were used to assess shoreline variability, sediment characteristics, and long-term shoreline evolution between October 2024 and July 2025. Results indicated that much of the eastern shoreline remained relatively stable, while greater variability was observed along the southern shoreline adjacent to the …

Faith-Informed Instruction In Secondary Mathematics: A Hermeneutic Phenomenological Study Of Lutheran Church–Missouri Synod Teachers, Jonathan Balsman

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to understand the phenomenon of faith-informed instruction as experienced by secondary mathematics teachers in Lutheran Church–Missouri Synod (LCMS) schools in the United States. The theory guiding this study was Vygotsky’s theory of social constructivism, which frames educators’ instructional and theological meaning-making as socially and contextually developed through collaborative, relational learning environments. The central research question guiding this study was: What are the lived experiences of LCMS secondary mathematics teachers as they practice faith-informed instruction? This study used a hermeneutic phenomenological design to interpret teacher meaning-making and reflective practice. Participants were selected using …

Double-Scoring: Reliable Extraction Of Strong Lottery Tickets, Bryce Christopherson, Jack Baretz, Darian Colgrove, Salah Dandan

Mathematics Faculty Publications

The lottery ticket hypothesis proposes that large random neural networks contain sparse subnetworks that can match the performance of dense models after compara- ble training. A stronger version asserts that sufficiently overparameterized random networks contain subnetworks that are already accurate before any weight training. Existing theory establishes that such strong lottery tickets exist, but reliable ex- traction remains difficult. We revisit edge-popup, a frozen-weight score-training method for extracting strong tickets, and identify layerwise sparsity selection as a central bottleneck. We introduce double-scoring, an augmented score-space parameterization that replaces a layerwise sparsity search with optimization over enlarged score tensors. We prove …

New Paradigm Of Forestry And Grassland Research Driven By Artificial Intelligence, Zhang Huaiqing, Jiaojun Zhu, Yang Liu, Tingdong Yang, Tian Gao, Jing Zhang, Xueyan Zhu, Yan Chen, Xian Jiang, Zeyu Cui, Jingwei Tan, Kexin Lei

Bulletin of Chinese Academy of Sciences (Chinese Version)

Addressing the current limitations in forestry and grassland research, particularly in cross-scale system cognition, complex process mechanism representation, and multi-scenario simulation, this study proposes an artificial intelligence-driven paradigm reconstruction framework, to shift the research model from experience-oriented approaches toward data- and intelligence-driven integration. On this basis, the study systematically establishes a multidimensional mapping between artificial intelligence and forestry and grassland research across research objects, processes, and objectives, and clarifies their intrinsic coupling mechanisms and technical pathways. Furthermore, it develops a foundational capability system to support the new paradigm from four key dimensions: data, computing power, models, and applications. By examining …

Construction Trends And Addressing Strategy Of Global Carbon Value System In View Of Chinese Enterprise, Xu Shuangqing, Liang Sun, Jianfeng Guo

Bulletin of Chinese Academy of Sciences (Chinese Version)

The global carbon value system represents a new consensus on values formed over decades of collective human action to address climate change. Its framework has been preliminarily established, with three dimensions—institutions, norms, and industries—forming a multidimensional space for expansion. Through this framework, the carbon value system can extend its influence to every aspect of human activity. At its core, the carbon value system involves reassessing the value of human activities and establishing new constraints for sustainable development. Consequently, enterprises must transform their traditional development models. For Chinese enterprises, the emergence of the global carbon value system during their pursuit of …

Progress And Prospective Of New Pollutants Study, Ruan Ting, Chunyang Liao, Yawei Wang, Maoyong Song, Yaqi Cai, Guibin Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The governance of new pollutants has been becoming a critical strategic demand for the high-quality development of China. The policy will be further advanced during the coming National 15th Five-Year Plan period. Nevertheless, significant challenges remain in aspects such as list of controlled chemicals, standard development, measurement methods, alternative approaches, and remediation techniques. Existing experience in addressing traditional pollutants remains insufficient to adequately address the concealed and complex ecological and/or health risks associated with new pollutants. Thus, a strengthening of basic research is the optimal approach to tackling these challenges and avoiding detours. To better identify the critical scientific challenges …

Understanding And Foresight On Construction Of Foundation Model Industry Innovation Ecosystem, Liu Liu, Chunhui Jia, Yangfan Han, Qiqi Zhang, Jialin Li, Dayuan Li, Junpu Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Foundation models are a key vehicle driving artificial intelligence toward general intelligence, and their industrialization urgently requires support from a systematic and collaborative innovation ecosystem. This study focuses on the construction of the foundation model industry innovation ecosystem. It first reviews the frontier progress and identifies its essence as a complex innovation network featuring the three-dimensional synergy of technological, organizational, and industrial architectures, and then analyzes the architecture along the upstream, midstream, and downstream of the industrial chain: the upstream supports computing power and data, the midstream undertakes algorithmic innovation and platform services, and the downstream realizes multi-scenario value transformation. …

Planetary Health: Scientific Frontier For Harmonious Coexistence Between Humans And Nature, Zhu Yongguan, Jue Liu, Hua Zheng, Yaoyang Xu, Weiqi Zhou, Hongliang Zhang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Against the backdrop of deeply intertwined global environmental change, biodiversity loss, and health risks, Planetary Health is emerging as a new interdisciplinary field that is gradually becoming the scientific frontier for understanding harmonious coexistence between humans and nature. This study systematically reviews the evolution of Planetary Health from the “Planetary Boundaries” theory to a comprehensive disciplinary framework. Through a paradigmatic comparison with concepts such as public health, global health, and One Health, it reveals that the core breakthrough of Planetary Health lies in redefining human health as an endogenous variable embedded within the stability of Earth’s natural systems. Three major …

Ai-Powered Knowledge Engines As Research Infrastructure For Systematic Knowledge Discovery, Gary Welz

Publications and Research

This paper proposes knowledge engines as a framework for understanding how intelligent systems — both human and artificial — systematically discover, integrate, and generate knowledge. We argue that history’s greatest scientific minds functioned as knowledge engines, processing information through iterative cycles of ingestion, analysis, synthesis, and communication, guided by curiosity and willingness to challenge established beliefs.

We propose a taxonomy of nine integrated capabilities — ingestion, digestion, analysis, calculation, comparison, connection, association, analogy, and multimodal communication — that any serious knowledge engine must combine systematically. The argument is deliberately integrative: achieving ambitious research goals requires orchestrating all nine capabilities within …

Ecological Gdp Of “Lucid Waters And Lush Mountains Are Invaluable Assets”, Wang Guangqian, Deyu Zhong

Bulletin of Chinese Academy of Sciences (Chinese Version)

Based on the concept of “lucid waters and lush mountains are invaluable assets”, this study investigates the theoretical connotation and accounting pathways of ecological GDP. (1) The core connotation of ecological value is elucidated from three dimensions—time, space, and civilization—and an economic quantification framework of principal–interest–interest rate is constructed. With four categories of ecological products as the foundation, the Green Certificate as the entitlement instrument, and a 5% annual simple interest rate as the accounting benchmark, ecological value is transformed from qualitative description to quantitative accounting. (2) The concept of ecological new quality productive forces is proposed, revealing its four-dimensional …

Building Ai-Native Innovation System To Drive Transformation And Innovation In Research Organization And Management Models, Hong Xuehai

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence (AI) is profoundly reshaping research paradigms. This study aims to analyze the intrinsic mechanisms through which AI empowers scientific research and its impact on the organizational management models of research. By summarizing what AI can and cannot do in empowering research, it reveals the current effectiveness and capability boundaries of AI in this domain. Based on the extraction of common core conditions for AI-empowered research and the deconstruction of typical cases of AI-enabled research organizational models, this study analyzes the differences between the organizational management model of AI-empowered research and traditional research organizational models. Furthermore, it proposes three …

Insights And Implications Of Ai For Science Strategies Of Major Science And Technology Powers, Zhang Zhiqiang, Yawei Shao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence (AI) is transitioning from a research aid to a scientific discovery agent. The new paradigm of “AI + Science” (AI for Science, AI4S) – the intelligent science paradigm (or the fifth paradigm of science) – characterized by the deep integration of artificial intelligence into the entire process of scientific discovery, is rapidly emerging and becoming a “new agent” for intelligent and autonomous execution of scientific discovery and technological invention as well as a key force in reshaping the human knowledge production system and the global landscape of technological competition. The intervention of AI in the field of knowledge …

Policy Reflections On Promoting Strategic Oriented Basic Research In China: Insights From The U. S. Department Of Energy’S Basic Research Funding System, You Yu, Yun Liu, Wenneng Zhou

Bulletin of Chinese Academy of Sciences (Chinese Version)

Strategy-oriented basic research is a key pathway to driving major original breakthroughs at the frontiers of science, serving national strategic needs, and securing a leading position in global science and technology. It is also a vital pillar for achieving high-level self-reliance and self-strengthening in science and technology and enhancing the capacity for original innovation. Faced with the urgent need to build a science and technology powerhouse and achieve breakthroughs in key core technologies, China has gradually improved its organizational framework for advancing strategy-oriented basic research and has established a solid foundation for policy support and resource allocation. Nevertheless, when measured …

Open Sharing And Collaborative Governance: Practices And Implications Of National Institutes Of Health’S Digital Transformation, Long Yuntao, Bingzhi Wang, Zheping Xu, Yang Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

With the rapid development of information technology, research projects and tasks of research institutes are increasing rapidly. Scientific and technological resources are the core and foundation of scientific research work, and scientific research institutes are faced with the needs of processing, management and coordination of a large number of scientific and technological resources. Digital transformation has become an inevitable choice for the high-quality development of scientific research institutes. The U.S. National Institutes of Health (NIH), as the world’s top scientific research institute, has continuously introduced a number of initiatives in the field of digital transformation, such as institutional reform policies, …

Career: New Insights Into The Ancient Carbon Cycle From Siliceous Deep-Sea Sediments, Donald Penman

Funded Research Records

No abstract provided.

Can An Ai System Be Creative? A Critical Perspective From Art And Engineering, Ivan Magrin-Chagnolleau

Presidential Fellows Articles and Research

This paper examines the question of whether artificial intelligence (AI) systems can be creative, approached from the dual perspective of a researcher trained in electrical engineering, pattern recognition, machine learning, and neural networks, who has also spent most of his life engaged in the arts as actor, stage and film director, writer, composer, and visual artist, and in philosophy. Drawing on Margaret Boden’s foundational framework — both her three properties of creativity (novelty, surprise, and value) and her three types of creative processes (combinatorial, exploratory, and transformational) — the paper argues that AI systems are structurally incapable of creativity in …

Reproduction Beyond Benchmarks: Constbert And Colbert-V2 Across Backends And Query Distributions, Utshab Kumar Ghosh, Ashish David, Shubham Chatterjee

Computer Science Faculty Research & Creative Works

Reproducibility must validate architectural robustness, not just numerical accuracy. We evaluate ColBERT-v2 and ConstBERT across five dimensions, finding that while ConstBERT reproduces within 0.05% MRR@10 on MS-MARCO, both models show a drop of 86-97% on long, narrative queries (TREC ToT 2025). Ablations prove this failure is architectural: performance plateaus at 20 words because the MaxSim operator's uniform token weighting cannot distinguish signal from filler noise. Furthermore, undocumented backend parameters create an 8-point gap due to ConstBERT's sparse centroid coverage, and fine-tuning with 3x more data actually degrades performance by up to 29%. We conclude that architectural constraints in multi-vector retrieval …

"The First Web Novel At 30: The Collection And The Creative Process", Robert Arellano, Scott Rettberg

ELO (un)supervised 2026

Summer 2026 marks the 30th anniversary of Sunshine '69, recognized as the first novelistic hypertext fiction published on the web. While the full work remains accessible online—an "(un)supervised" preservation achievement in itself—the archive remains split between boxes and memory. This conversation between the work's creator and a major scholar in electronic literature documents both specific preservation challenges and systemic patterns in what the field chooses to preserve.

Topics include: figuring out web-born composition before established methodologies existed; the three decades of technical decisions that kept a 1996 work alive through format obsolescence and server migrations; and what gets lost …

Ni2-Imido Bispincer Platforms: Cooperative Reactivity Enabled Through Substrate Addition Across A Ni2n Unit, David De Los Santos, Kritika Gour, Manar M. Shoshani

School of Integrative Biological & Chemical Sciences Faculty Publications

Transition metal imido complexes are renowned for their capacity to undertake challenging 1,2 additions owing to the high basicity of the imido moiety. Access to transition metal imidos is often limited to the addition of organic azides to metal precursors, hindering the design of molecular constructs incorporating imido units. Bimetallic bispincer complexes, 1 and 2, are presented, which are anchored by a central imido moiety supported by pyridyl imine donors, forming highly planarized Ni2N-aryl cores. Complex 2, which also features a Ni─Ni σ-bond, is able to engage in cooperative substrate cleavage of main group hydrides via a formal 1,2 addition …