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Articles 241 - 270 of 32526
Full-Text Articles in Entire DC Network
Evolutionary Neural Architecture Search: A Survey, Ferda Nur Özçeli̇k, Mehmet Önder Efe
Evolutionary Neural Architecture Search: A Survey, Ferda Nur Özçeli̇k, Mehmet Önder Efe
Turkish Journal of Electrical Engineering and Computer Sciences
Deep Neural Networks (DNNs) have achieved remarkable success across diverse machine learning applications, yet designing effective architectures remains a laborious, expert-driven process. Neural Architecture Search (NAS) was introduced to automate this process, with Evolutionary NAS (ENAS) emerging as one of the most effective and widely adopted NAS paradigms. This survey provides a comprehensive and systematic review of 164 ENAS studies published between 2020 and 2024, categorized according to the specific evolutionary algorithm employed as the search strategy. Unlike prior surveys—which either treat evolutionary methods at a high level or focus on general NAS pipelines—this study is, to the best of …
A Revenue-Driven Approach For Enhanced Task Utilization In Vehicular Cloud Computing, Ashish Singh Saluja, Satyabrata Das, Sanjib Kumar Nayak, Sohan Kumar Pande
A Revenue-Driven Approach For Enhanced Task Utilization In Vehicular Cloud Computing, Ashish Singh Saluja, Satyabrata Das, Sanjib Kumar Nayak, Sohan Kumar Pande
Turkish Journal of Electrical Engineering and Computer Sciences
Vehicular networks support intelligent transportation through vehicle-to-roadside Units (V2R) and vehicle-to-vehicle (V2V) communication but face challenges from dynamic topologies, limited RSU coverage, and bandwidth scarcity, which impact service delivery and revenue. RDA-ITU addresses these challenges by integrating V2R and V2V paradigms to maximize RSU revenue, enhance service availability, and improve system efficiency. It dynamically allocates services based on real-time network conditions and vehicle mobility, leveraging V2V relays to optimize both RSU-direct and cooperative communication. Through extensive simulations, RDA-ITU significantly outperforms four baselines: RBSM, VVMM-U, VVMM-LW, and VVMM-MA. It achieves 81.1% higher total revenue, 154.8% more completed requests, and 103.6% higher …
Class-Aligned Frequency Augmentation Using Variational Mode Decomposition Forfew-Shot Image Classification, Leila Boussaad
Class-Aligned Frequency Augmentation Using Variational Mode Decomposition Forfew-Shot Image Classification, Leila Boussaad
Turkish Journal of Electrical Engineering and Computer Sciences
Few-shot image classification benefits from data augmentation, yet most existing methods operate in pixel space with limited control over spectral semantics. We introduce a lightweight, frequency-guided augmentation strategy based on Variational Mode Decomposition (VMD). Our method constructs an offline, per-class ModeBank by decomposing downsampled luminance patches and retaining midband modes that encode class-specific texture patterns. During episodic training, VMD is never executed online: instead, for each support image, a same-class midband mode is selected and blended using PSNR-targeted scaling with a luminance energy cap, ensuring perceptual consistency. The augmentation is fast, reproducible, class-consistent, and integrates seamlessly into standard metric-based pipelines …
Llm-As-A-Judge For Infection Prevention And Control And Antimicrobial Resistance Impact: Comparing Three Main Llms Vs. Human Experts' Assessment, Marcello Di Pumpo, Leonardo Villani, Maria Rosaria Gualano, Danilo Buonsenso, Francesca Raffaelli, Daniele Donà, Patrizia Laurenti, Vittorio Maio, Stefania Boccia, Walter Ricciardi
Llm-As-A-Judge For Infection Prevention And Control And Antimicrobial Resistance Impact: Comparing Three Main Llms Vs. Human Experts' Assessment, Marcello Di Pumpo, Leonardo Villani, Maria Rosaria Gualano, Danilo Buonsenso, Francesca Raffaelli, Daniele Donà, Patrizia Laurenti, Vittorio Maio, Stefania Boccia, Walter Ricciardi
College of Population Health Faculty Papers
BACKGROUND: Large language models (LLMs) are increasingly used to generate health information, yet their reliability as evaluators remains unclear. This study investigated the feasibility of an LLM-as-a-judge methodology in the context of infection prevention and antimicrobial resistance (AMR), comparing automated ratings with human expert benchmarks.
METHODS: We performed a secondary analysis of an expert-annotated dataset of health messages. Three leading LLMs (ChatGPT, Claude, Gemini) independently evaluated the same messages using an adapted DISCERN tool across five domains: information reliability, quality, AMR impact, persuasiveness, and overall score. We utilized descriptive statistics, intra-rater reliability tests, and mixed-effects ordinal regression to analyze divergence …
Cybersecurity Governance Of Industrial Iot In Sub-Saharan Africa: Policy Gaps, Threat Landscape, And Lessons From Comparative African Contexts, Faztudo Languisse Eng.
Cybersecurity Governance Of Industrial Iot In Sub-Saharan Africa: Policy Gaps, Threat Landscape, And Lessons From Comparative African Contexts, Faztudo Languisse Eng.
Journal of Cybersecurity Education, Research and Practice
The rapid deployment of Industrial Internet of Things (IIoT) systems across Sub-Saharan Africa's extractive, energy, logistics, and agro-industrial sectors has introduced a cybersecurity challenge of growing urgency: industrial networks that were designed for operational efficiency are increasingly exposed to cyber threats for which neither the organizations nor the regulatory frameworks are adequately prepared. This article examines the cybersecurity governance of IIoT systems in a developing African economy, using Mozambique as a primary case study and drawing comparative lessons from South Africa, Rwanda, and Kenya. Through an integrative literature review and documentary analysis of national digital, cybersecurity, and industrial policies, the …
Operator Theoretic Methods For Coupled Pde In General Geometries, Yuhao Mu
Operator Theoretic Methods For Coupled Pde In General Geometries, Yuhao Mu
Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–
This thesis develops and applies operator theoretic methods applied to coupled PDE analysis in general geometries, in which the coupling involves interchange across a boundary. The general geometries refer to domains with merely Lipschitz continuous boundaries (e.g. any non-convex polygon), as opposed to those with any further smoothness conditions on the boundary. The key results include a new pressure elimination method for coupled fluid–structure interaction (FSI) PDEs with boundary interchange, which allows an explicit semigroup representation of the PDE in terms of just the fluid and structure variables. This novel technique, valid over arbitrary bounded Lipschitz domains, leads to a …
Taxing Ai In The Wake Of The Emergence Of Agentic Ai, Reuven S. Avi-Yonah, Herbert Snitz
Taxing Ai In The Wake Of The Emergence Of Agentic Ai, Reuven S. Avi-Yonah, Herbert Snitz
Articles
This article addresses taxation measures to regulate AI agents (i.e., AI that is not fully under the control of humans, including both ANI and AGI). In each case, the focus is on what the agent’s capabilities would be, not on how it becomes capable of successfully performing its tasks (though the latter would likely be relevant to important philosophical questions, e.g., might robots achieve sentience or consciousness, and if so, would they have rights?). Regarding mirroring what we human beings can do, the hallmark of AGI is that it will not be task-specific (like ANI), but will possess broad capabilities, …
Signal And Substance: Why Methodological Sophistication Fails To Guarantee Inference, Aamir Rashid, Rizwana Rasheed
Signal And Substance: Why Methodological Sophistication Fails To Guarantee Inference, Aamir Rashid, Rizwana Rasheed
Publications and Research
Despite increasing analytical sophistication, empirical research in organization studies continues to suffer from fragile inference, uneven theoretical accumulation, and contested credibility. This paper seeks to explain why these problems persist by shifting attention from authors’ methodological choices to the evaluative dynamics of peer review. Adopting a conceptual and theory-analytic approach, the paper theorizes peer review as an inferential gatekeeping system. Drawing on research design, theory evaluation, and philosophy-of-science literatures, this study develops an analytical framework to examine how evaluative routines shape what constitutes empirical rigor during the review process. The analysis identifies five recurring reviewer blind spots: inferential scope inflation, …
Current Aspects Of Eco-Physiological Studies Of Meadow Plants, Momcilo Konic
Current Aspects Of Eco-Physiological Studies Of Meadow Plants, Momcilo Konic
IGC Proceedings (1977-2023)
Basic parameters applied in eco-physiological studies of meadow plants are: water balance (hydration, transpiration intensity, amounts and forms of water, water deficit, etc.), assimilation balance (CO2 balance, assimilation performance, compensation effect), matter production. Eco-physiological studies should be followed by microclimatic measurements and the anatomical analysis of the meadow plants under study. Eco-physiological studies of meadow plants, if performed in a complex and systematic way, constitute the safest basis for detennining the characters of the entire meadow plant community under the concrete conditions of natural factors prevailing in terms of natural conditions and human influence.
On Universal C∗ Algebras Associated To Operator Spaces And Generalized Crossed Products, Sayan Kansa Banik
On Universal C∗ Algebras Associated To Operator Spaces And Generalized Crossed Products, Sayan Kansa Banik
Doctoral Theses
In my thesis, we study generalized crossed product constructions of the group \( C^* \)-algebra \( C^*(G) \) with respect to certain completely positive maps, where \( G \) is assumed to be a discrete amenable group. We also investigate the universal \( C^* \)-algebra \( \mathcal{E}_\alpha \) introduced by Hirshberg, which is constructed from \( C^*(G) \) and a pure injective homomorphism \( \alpha \colon G \to G \). In particular, we analyze its relationship with Exel's construction of generalized crossed products associated with the endomorphism of \( C^*(G) \) induced by \( \alpha \), together with an appropriate …
Open Neighbourhood Edge Degree And Metric Descriptors Qspr And Multi Criteria Analysis Of Chemicals And Antiviral Drugs, Gayathri A Ms
Open Neighbourhood Edge Degree And Metric Descriptors Qspr And Multi Criteria Analysis Of Chemicals And Antiviral Drugs, Gayathri A Ms
Theses and Dissertations
Chemical Graph theory offers powerful computational methods for evaluating chemical structures, significantly impacting cheminformatics and drug analysis. It provides a robust mathematical framework to represent, model, and analyse molecular systems through topological indices and graph invariants. These indices serve as effective numerical descriptors, encapsulating significant structural information that enhances the prediction of physicochemical and biological properties. This thesis utilizes mathematical modeling, algorithmic computation, and decision making process to derive extensive insights to drug discovery and molecular analysis.
The thesis introduces a new class of topological indices ONE1, ONE2, ONE3, ONE4, ONE5,ONE6 and ONE7 based on open-neighbourhood-edge-degree and it evaluates the …
Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar
Dynlp: Parallel Dynamic Batch Update For Label Propagation In Graph-Based Semi-Supervised Learning, S. M. Shovan, Arindam Khanda, S. M. Ferdous, Sajal K. Das, Mahantesh Halappanavar
Computer Science Faculty Research & Creative Works
Semi-supervised learning aims to infer class labels using only a small fraction of labeled data. In graph-based semi-supervised learning, this is typically achieved through label propagation to predict labels of unlabeled nodes. However, in real-world applications, new data often arrives in batches, and stale data often becomes irrelevant. Each time a new batch appears, reapplying the traditional label propagation algorithm to recompute all labels is redundant, computationally intensive, and inefficient. To address the absence of an efficient label propagation update method, we propose DynLP, a novel GPU-centric Dynamic Batched Parallel Label Propagation algorithm that performs only the necessary updates, propagating …
The Breeding Of Tetraploid Alsike Clover (Trifolium Hybridum L.) For Mowing And Grazing, Vladimir Malashenko, Svetlana Cheprasova, Antonina Fadeeva
The Breeding Of Tetraploid Alsike Clover (Trifolium Hybridum L.) For Mowing And Grazing, Vladimir Malashenko, Svetlana Cheprasova, Antonina Fadeeva
IGC Proceedings (1977-2023)
An account is given of the long-range importance that should be attributed to the use of No. 701 tetraploid alsike clover as an early maturity, fast-growing, high-yield competitive leguminous plant for irrigated pastures and arable forage cultivation.
Leguminous plants are of very great importance to forage production at large. They actually constitute a major source for nitrogen supply. This underlines their decisive role in grassland farming as a device by which to get to grips with the nitrogen deficit. Pasture productivity can best be improved by proper arrangement of plant associations with forage crop partners of the legume family which …
Possibilities Of Improving The Feeding Value Of Alfalfa By Breeding, R Steuckardt, I Bocsa
Possibilities Of Improving The Feeding Value Of Alfalfa By Breeding, R Steuckardt, I Bocsa
IGC Proceedings (1977-2023)
1. The character "in vitro digestibility" represents a complex factor. It is fixed by genetic constitution. Certain correiations were found to exist between the digestibility coefficients (DC) established in the individual cuts, as well as between the DC found in the two years of alfalfa use tested.
2. The in vitro digestibility shows sufficient variability, thus offering an adequate range for a selection programme to improve the feeding value of alfalfa. With such programmes it is, however, necessary at the same time to maintain or even to further improve matter production. The effect of characters correlating with digestibility (positive correlation) …
A Study Of Seed Formation In Alfalfa With Respect To Environmental Conditions And Pollinating Mode, Alena Vachunova
A Study Of Seed Formation In Alfalfa With Respect To Environmental Conditions And Pollinating Mode, Alena Vachunova
IGC Proceedings (1977-2023)
The influence of pollinating mode and of conditions for seed formation was studied on 30 clones of different genetic constitution. The average yields per plant have changed markedly under the influence of environmental conditions, especially of variable precipitation.
The correlation between the years was positive and significant. The number of flowers forming pods and also the average number of seeds per flower and per pod are in close relation to the seed yield of the individual plants, not only under self-pollination but also under open pollination. In the dry year of 1973, the correlation coefficients under open pollination were lower …
The Effects Of Global Radiation Before Harvesting Upon The Digestibility Of The Dry Matter Of Some Grass Species, W Schoberlein, W Lampeter
The Effects Of Global Radiation Before Harvesting Upon The Digestibility Of The Dry Matter Of Some Grass Species, W Schoberlein, W Lampeter
IGC Proceedings (1977-2023)
Four micro-trials with 6 breeding varieties each of Lolium multijlorum, Lolium perenne and Dactylis glomerata (early and late groups) were carried out under field conditions. Neither artificial reduction in daylight by means of a sunshade nor storage of the fresh mass in a dark room with the stems kept in water or else in a plastic bag resulted in abrupt decrease in digestibility as common under conditions of low global radiation. The findings point to the possibility that the composition of the diffuse light on days with poor radiation deviates from the diffuse light under a sunshade on days with …
The Gene Pool And Its Use In Breeding Grassland Plants, Anna Novoselova
The Gene Pool And Its Use In Breeding Grassland Plants, Anna Novoselova
IGC Proceedings (1977-2023)
1. The gene pool of grassland plants is of great diversity and localized in certain centres of origin where the carriers of germ plasma are concentrated for the most important biological characters and properties of a great variability of species.
2. New intensive varieties for mowing and grazing have been bred by advanced breeding methods and by taking advantage of the gene pool of the most important plant species throughout the world.
3. Wild-growing species were found to have great prospects for opening up soils of poor productivity by mowing and grazing use. They constitute a great reserve of genetic …
The Environment And Population Differences In Anjan Grass (Cenchrus Ciliaris) In Western India, S C. Pandeya
The Environment And Population Differences In Anjan Grass (Cenchrus Ciliaris) In Western India, S C. Pandeya
IGC Proceedings (1977-2023)
Cenchrus ciliaris (anjan or buffel grass) is a gregarious fodder species with high nutritive value. The species is an inhabitant of drier sandy areas throughout Africa, Canary Island, Madagascar and eastwards to India, where it mostly occurs in western parts of the country, constituting the States of Gujarat, Rajasthan, Hayana and the adjoining portions of Punjab, U ttar Pradesh and Madhya Pradesh ( called here in as Western India). In Western India, Cenchrus ciliaris (Cc) variously dominates the naturally occurring grazing lands exhibiting great morphological variations with respect to habit. and spike characters. The ecoclimate of Western India is arid …
Crustal Structure Of The Vøring Plateau And Vøring Spur From Joint Refraction And Reflection Travel-Time Tomography, Anika Nawar Mayeesha
Crustal Structure Of The Vøring Plateau And Vøring Spur From Joint Refraction And Reflection Travel-Time Tomography, Anika Nawar Mayeesha
Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research
Crustal architecture of the Vøring Plateau and Vøring Spur in the mid-Norwegian continental margin remains debated because the geophysical data in the area do not uniquely constrain whether the crust is continental, oceanic, or transitional. This study reanalyzes wide-angle ocean-bottom seismometer data from Profile 11-03 across the Vøring passive continental margin using joint travel-time tomography of crustal refractions and Moho reflections. A total of 6,760 first-arrival picks and 542 PmP picks from sixteen instruments were inverted for P-wave velocity and reflector depth. Three starting models were inverted independently to test sensitivity to the initial crustal configuration. The first two used …
Block Kinematics, Interseismic Coupling And Fault Slip Rates In The Aegean Region From Gps And Earthquake Slip Vector Data: 1. Upper Plate Structures, Konstantinos Chousianitis, Sotiris Sboras, Volkan Özbey, Robert Mccaffrey, Semih Ergintav
Block Kinematics, Interseismic Coupling And Fault Slip Rates In The Aegean Region From Gps And Earthquake Slip Vector Data: 1. Upper Plate Structures, Konstantinos Chousianitis, Sotiris Sboras, Volkan Özbey, Robert Mccaffrey, Semih Ergintav
Geology Faculty Publications and Presentations
We represent the active deformation of the Aegean region with an elastic‐kinematic block model composed of a finite number of rotating crustal blocks whose boundaries coincide with major active structures. A total of 832 GPS velocities and 146 earthquake slip vectors were inverted to provide estimates of block rotations and interseismic locking on block‐bounding faults so as to best reproduce the observed deformation field. Our regional model allowed us to derive a self‐consistent set of geodetic slip rates for upper plate faults and the Hellenic subduction system, the results of which are presented in a companion paper, and to determine …
There Is No Free Benchmark: An Institutional View Of Legal Ai Benchmarking, Neel Guha, Andy K. Zhang, Christine Tsang, Christopher D. Manning, Julian Nyarko, Daniel E. Ho
There Is No Free Benchmark: An Institutional View Of Legal Ai Benchmarking, Neel Guha, Andy K. Zhang, Christine Tsang, Christopher D. Manning, Julian Nyarko, Daniel E. Ho
Faculty Scholarship
Despite substantial excitement around the use of AI in law, little information exists on the performance and associated risks of the domain’s widely marketed tools. Recent work, for instance, has demonstrated the significant potential for “hallucinations” — wherein models make up facts, law, and precedent — leading Chief Justice Roberts to spotlight this risk in his annual report on the judiciary. We argue that there is a need for public AI benchmarking in law. First, relative to other AI application domains, the legal AI ecosystem lacks legibility — there is little information about the design and performance of many commercial …
Prediction Of Satellite Temperature During An Orbit Of A Cubesat, Michael Reynolds
Prediction Of Satellite Temperature During An Orbit Of A Cubesat, Michael Reynolds
Honors Theses
This thesis develops a thermal-simulation strategy for predicting CubeSat component temperatures, applied to Jag-Sat-1, a CubeSat developed at the University of South Alabama and deployed from the International Space Station in 2022. The orbit was reconstructed from two-line element (TLE) data using simplified general perturbations (SGP4) propagation, and spacecraft attitude was recovered from onboard gyroscope measurements. Sunlight, penumbra, and umbra intervals were computed geometrically, and the external radiative environment — direct solar, Earth infrared, and albedo heat fluxes — was modeled using orientation-dependent view factors. These time-varying fluxes drove a transient finite-element thermal simulation of the full satellite geometry in …
On The Side And Angle Mixtures Expressed By Triangles: Phase Diagrams Based On Intensive State Properties, Daniel Graham
On The Side And Angle Mixtures Expressed By Triangles: Phase Diagrams Based On Intensive State Properties, Daniel Graham
Chemistry: Faculty Publications and Other Works
This is a lecture packet focused on the side and angle mixtures of structures at the center of the planar geometry universe. The intensive states of triangles are charted with the help of phase diagrams—long-standing tools in chemical thermodynamics and materials science. The intended audience consists of students and teachers—college and high school—seeking fresh perspectives, projects, and discussion topics surrounding age-old systems.
Elemental Analysis Of Upper Devonian To Lower Mississippian Organic-Rich Mudstone Cores From Kentucky By Portable X-Ray Fluorescence (Pxrf), Alex M. Washburn
Elemental Analysis Of Upper Devonian To Lower Mississippian Organic-Rich Mudstone Cores From Kentucky By Portable X-Ray Fluorescence (Pxrf), Alex M. Washburn
KGS Research Data Set
This dataset contains high-density portable X-ray fluorescence (pXRF) elemental analyses of 1,867 m (6,125 ft) of Upper Devonian to Lower Mississippian organic-rich mudstone cores from Kentucky. Analyses were collected from cores across the Illinois Basin, Cincinnati Arch, and Appalachian Basin to support regional evaluation of elemental variability, chemostratigraphy, and redox-sensitive trace-metal enrichment in Devonian–Mississippian mudstone successions. All measurements were conducted using a Bruker Tracer 5 pXRF analyzer with the factory “Mudrock Air” calibration, using analytical settings optimized for both low-atomic-number elements and transition metals/redox-sensitive trace elements. Reference materials SARM-41 and SGR-1 were analyzed throughout the analytical sequence to monitor instrument …
The Interwoven Dynamics Of Climate, Fire, Resilience And Orangutan Survival In Central Kalimantan’S Peat Swamp Forest, Putu Pujiantari
The Interwoven Dynamics Of Climate, Fire, Resilience And Orangutan Survival In Central Kalimantan’S Peat Swamp Forest, Putu Pujiantari
Graduate Theses and Dissertations
Tropical peat swamp forests are globally significant carbon reservoirs and biodiversity strongholds, yet they face escalating threats from climate change, fire, and anthropogenic disturbances. This dissertation investigates the interwoven dynamics of climate, fire, forest resilience, and orangutan survival in Central Kalimantan, Indonesia, a region which was transformed by the failed Mega Rice Project and recurrent catastrophic wildfires for decades. Using a multi-scale approach that integrates remote sensing time-series analysis (2001–2024),nlandscape-scale disturbance mapping (2005–2025), and fine-scale movement ecology, this research tests three core hypotheses: (1) moisture availability is the dominant climatic driver of wildfire activity, operating through non-linear thresholds; (2) post-fire …
Anomaly Management In Unmanned Aerial Vehicles: A Systematic Literature Review, Ivan Tan Wei Han, Christopher M. Poskitt, Lingxiao Jiang, Lwin Khin Shar
Anomaly Management In Unmanned Aerial Vehicles: A Systematic Literature Review, Ivan Tan Wei Han, Christopher M. Poskitt, Lingxiao Jiang, Lwin Khin Shar
Research Collection School Of Computing and Information Systems
Unmanned Aerial Vehicles (UAVs) are increasingly deployed in safety-critical applications such as logistics, surveillance, disaster response, and urban air mobility. While their autonomy enables powerful capabilities, it also introduces vulnerabilities due to hardware faults, software defects, communication failures, and adversarial interference. This survey presents a comprehensive review of research studies closely related to UAV anomalies published between 2015 and 2025, covering 111 papers from academic and industrial sources. We introduce a unified five-pillar taxonomy—anomaly generation, prevention, detection, recovery, and analysis—that organizes existing work across the full anomaly management lifecycle. In contrast to prior surveys that focus primarily on detection algorithms, …
New Algorithms For Fully-Dynamic K-Center With Outliers, Junyu Huang, Zhize Li, Zhen Zhang, Xujia Li, Jianxin Wang, Qilong Feng
New Algorithms For Fully-Dynamic K-Center With Outliers, Junyu Huang, Zhize Li, Zhen Zhang, Xujia Li, Jianxin Wang, Qilong Feng
Research Collection School Of Computing and Information Systems
In this paper, we study the fully dynamic k-center with outliers problem, where points are inserted and deleted over time and the goal is to maintain an approximate clustering while discarding up to z outliers. Existing algorithms typically rely on radius guessing to maintain cluster representations, leading to update and query times that depend explicitly on the aspect ratio Δ. We propose a layered-sampling framework that avoids radius guessing by maintaining a hierarchy of sampled structures, which can separate most inliers from potential outliers and refine the remaining uncertain points. The resulting algorithm achieves Õ(k²/ε⁴) update and query time independent …
Chaotropic And Kosmotropic Effects Of Brines On Protein Structure: Habitability Across The Solar System, Shelby Dawn Osborne
Chaotropic And Kosmotropic Effects Of Brines On Protein Structure: Habitability Across The Solar System, Shelby Dawn Osborne
Graduate Theses and Dissertations
Salts exhibit unique and specific effects on biomolecular structure depending on the physical nature of the salt (ion density, formation of hydration shells, direct binding to protein). This thesis implements biochemical, thermodynamic, and computational methods to investigate how the nature of the salt effects protein structure, which aids in defining the habitability of various brine solutions. By using simple proteins and solar system relevant salts, we inspect the physical reactions of proteins to these saltwater environments to understand which salts stabilize or destabilize protein structure. Several methods of experimentation are utilized to provide an understanding of the interaction relevant to …
Hsv-1 Us3 Hijacks Conserved Actin Regulatory Complexes To Drive F-Actin Remodeling, Md Imran Hossain, Md Arifuzzaman, Md Mehedi Hasan, Seung Jong Park, Leila Rahimian, Ojasvi Dutta, Vladimir Chouljenko, Harikrishnan Mohan, Reza Ghavimi, Konstantin G. Kousoulas
Hsv-1 Us3 Hijacks Conserved Actin Regulatory Complexes To Drive F-Actin Remodeling, Md Imran Hossain, Md Arifuzzaman, Md Mehedi Hasan, Seung Jong Park, Leila Rahimian, Ojasvi Dutta, Vladimir Chouljenko, Harikrishnan Mohan, Reza Ghavimi, Konstantin G. Kousoulas
Computer Science Faculty Research & Creative Works
The herpes simplex virus 1 (HSV-1) US3 is a multifunctional serine/threonine kinase that promotes HSV-1 replication and spread. But its role and the mechanisms by which US3 regulates actin cytoskeletal remodeling remain poorly defined. We combined flow cytometry, confocal microscopy, immunoprecipitation-mass spectrometry (IP-MS), protein complex mapping, and machine learning to characterize US3-mediated F-actin dynamics. Flow cytometry and confocal microscopy showed that wild-type HSV-1 induces significant F-actin remodeling, while the ΔUS3 mutant displays F-actin levels comparable to uninfected cells, identifying US3 as a key regulator. IP-MS identified 47 high-confidence US3 interactors enriched in conserved actin regulatory complexes, including Arp2/3 nucleation machinery, …
Knowledge-State Generative Agents For Pre-Assessment Question Evaluation, Ping Fan Ke, Yi Meng Lau, Siaw Ling Lo
Knowledge-State Generative Agents For Pre-Assessment Question Evaluation, Ping Fan Ke, Yi Meng Lau, Siaw Ling Lo
Research Collection School Of Computing and Information Systems
This paper introduces a Knowledge‑State Generative Agent framework for evaluating the quality of pre‑assessment questions. The framework employs large language model (LLM)–based agents prompted to adopt a teacher persona to simulate the responses of students with and without mastery of targeted knowledge components. A preliminary empirical study using archival data from 424 students enrolled in an Information Systems Management course indicates that the proposed approach yields interpretable metrics under Classical Test Theory. Results further show that agents instantiated with the relevant mastered knowledge components exhibit systematically higher performance than agents lacking such mastery. In addition, the study suggests that teacher-persona …