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Pastoral Systems Of Central Himalaya: How Long Will They Survive?, K S. Rao, K G. Saxena Sep 2024

Pastoral Systems Of Central Himalaya: How Long Will They Survive?, K S. Rao, K G. Saxena

IGC Proceedings (1977-2023)

Pastoral systems of Central Himalaya are very old and until recent time were in balance with environment, Recent changes in socio­political setup have drastically altered the status of these systems. The change of political power in trans-Himalayan Tibetean plateau has resulted in closure of international boarders, thus taking away the mercantile aspects of pastoralists and reducing pastoral area. Increased human disturbances on fragile Himalayan marginal lands and excessive onslaught on forests for fuel and fodder by the sedentary population has resulted in degradation and non-productive grasslands which do not help pastoralists sustain existing systems. Changes in relations between migratory pastoralists …


A Preliminary Discussion Of The Management And Administration Of Yunwu Mountain Natural Grassland Reserve In China, Zhao Zhiyi, Yang Ailian Sep 2024

A Preliminary Discussion Of The Management And Administration Of Yunwu Mountain Natural Grassland Reserve In China, Zhao Zhiyi, Yang Ailian

IGC Proceedings (1977-2023)

The advantages and problems encountered in the establishment of a grassland reserve are described. The conflicts between local farmers' requirement to feed and water livestock and the conservation strategy of natural grassland are discussed.


Effect Of Sewage Sludge On The Mineral Composition Of Corn, Arthur E. Peterson, P E. Speth, P L. Schlecht Sep 2024

Effect Of Sewage Sludge On The Mineral Composition Of Corn, Arthur E. Peterson, P E. Speth, P L. Schlecht

IGC Proceedings (1977-2023)

For the past 12 years, digested sewage sludge from the Milwaukee Metropolitan Sewerage District has been applied to a Plano silt loam (prairie) soil near Elkhorn, Wisconsin, and corn raised as the indicator crop. The corn has been harvested as silage and fed to dairy cnttle. The amounts of macro-, micro-, and heavy metals contained in this forage were compared with the amounts contained in the untreated areas, and in the forage produced by a sustainable agriculture study on the same experimental station. None of the heavy metals have moved out of the plough layer (lop 25 cm). The uptake …


Sustainable Direction For Resource Management An Assessment Of The Regional Council Role, Allan Lohrey Sep 2024

Sustainable Direction For Resource Management An Assessment Of The Regional Council Role, Allan Lohrey

IGC Proceedings (1977-2023)

The 1980s has seen an increased world awareness of the concept of sustainability. In 1991 New Zealand enacted the Resource Management Act (RMA) which reflected society's concern for a need to consider future generations when making decisions relating to the use of natural resources. Regional councils have been allocated the role within the Act to promote sustainable management at the regional level. The short term challenge to regional councils is to manage resources in manner which strikes a pragmatic balance between the ongoing needs of society and the need to provide resources for future generations. Regional councils will know they …


Application Of Dairy Manure On Alfalfa, Stephen J. Herbert, Jayarm Daliparthy, P L.M Veneman Sep 2024

Application Of Dairy Manure On Alfalfa, Stephen J. Herbert, Jayarm Daliparthy, P L.M Veneman

IGC Proceedings (1977-2023)

Applying dairy manure to alfalfa (Medicago sativa L.) as ,in alternative 10 excess application to· corn (Zea mays L.) may reduce nitrate pollution of groundwater. Field experiments were conducted at 2 sites in Massachusetts, USA, lo study the impact or dairy manure application to alfalfa on forage yield, weed infestation· and nitrate movement. Treatments were an unfertilized (no N) check.· plot, low and high manure (112 and 336 kg N/ha/year equivalerit), and low and high N fertiliser (112 and 336 kg N/ha/year from NH4NO3),'. Liquid dairy manure was applied 10 • alfalfa immediately· after 1st· cutting during spring …


Neurosymbolic Cognitive Methods For Enhancing Foundation Model-Based Reasoning, Kaushik Roy, Siyu Wu, Alessandro Oltramari Sep 2024

Neurosymbolic Cognitive Methods For Enhancing Foundation Model-Based Reasoning, Kaushik Roy, Siyu Wu, Alessandro Oltramari

Faculty Publications

Foundation models have emerged as powerful tools, exhibiting extraordinary performance across various tasks, such as language processing, visual recognition, code generation, and human-centered engagement. However, recent studies have highlighted their limitations when grounded, abstract, and generalized reasoning capabilities are required. Complex tasks often involve multiple hierarchical reasoning steps, which are typical features of human thinking processes. In fact, in this chapter we claim that cognitively-inspired computational models, such as the so-called Common Model of Cognition, are key to enable complex reasoning within foundation model-based artificial intelligence (AI) systems. We investigate neurosymbolic approaches for mapping AI system components to those of …


Breakthrough Conductivity Enhancement In Deep Eutectic Solvents Via Grotthuss-Type Proton Transport, Desiree Mae Prado, Clemens Burda, Anthony Jahng, Kayla Poling Sep 2024

Breakthrough Conductivity Enhancement In Deep Eutectic Solvents Via Grotthuss-Type Proton Transport, Desiree Mae Prado, Clemens Burda, Anthony Jahng, Kayla Poling

Faculty Scholarship

There is an increasing demand for the development of ion-conducting electrolytes for energy storage systems. Much attention is directed toward deep eutectic solvents as potential candidates. In the search for highly conductive systems, the possibility of designing deep eutectic solvents with Grotthuss-type proton transport is widely overlooked. Herein, ethaline, a mixture of choline chloride and ethylene glycol is used in a 1:2 molar ratio, to induce a significant conductivity increase with the addition of water and sulfuric acid (H₂SO₄). The achieved breakthrough conductivity is analyzed experimentally and simulated with ab initio molecular dynamics (AIMD). At sufficient water content, an H-bonding …


Editorial: Critical Praxis And The Social Imaginary For Sustainable Food Systems, Max Stephenson Jr., Kim Niewolny, Laura Zanotti, Anna Erwin Sep 2024

Editorial: Critical Praxis And The Social Imaginary For Sustainable Food Systems, Max Stephenson Jr., Kim Niewolny, Laura Zanotti, Anna Erwin

School of Earth, Environmental, & Marine Sciences Faculty Publications

No abstract provided.


Editorial: Centering Humanism In Stem Education, Desirée Forsythe, Sheila S. Jaswal, Bryan Dewsbury, Susannah Mcgowan Sep 2024

Editorial: Centering Humanism In Stem Education, Desirée Forsythe, Sheila S. Jaswal, Bryan Dewsbury, Susannah Mcgowan

Biology, Chemistry, and Environmental Sciences Faculty Books and Book Chapters

"To understand why this Research Topic exists, it is important to recall the original goal from our call for proposals: to reorient STEM researchers and practitioners to reconsider the actual purpose of the practice of teaching and learning. Bryan Dewsbury often invokes us in his writing and talks to understand our why. As educators, we wish to provide insights, practices, and proposed theories to reflect on our WHY in STEM education—from one instructor’s empathetic approach to understanding the undergraduate student experience in gateway courses to the cultural initiation ceremonies at the disciplinary level. These components of humanism and the lens …


Assessing The Adequacy Of A Prediction Model, Abhaya Indrayan, Sakshi Mishra Ms Sep 2024

Assessing The Adequacy Of A Prediction Model, Abhaya Indrayan, Sakshi Mishra Ms

COBRA Preprint Series

No abstract provided.


The Heat Kernel On A Finite Graph In Different Time-Scales, Yang Chen, Jay Jorgenson, Luis Lopez, Lejla Smajlovic Sep 2024

The Heat Kernel On A Finite Graph In Different Time-Scales, Yang Chen, Jay Jorgenson, Luis Lopez, Lejla Smajlovic

Turkish Journal of Mathematics

Let G be a finite, weighted graph, and let [[EQUATION]] be a Time-scale with a fixed point [[EQUATION]] such that sup[[EQUATION]]. In this paper we construct the heat kernel on G in Time-scale [[EQUATION]] in terms of a certain convolution series involving he heat operator acting on a parametrix, which is a fairly general function depending on the vertex set of G and the time variable [[EQUATION]]. We develop some applications by choosing different parametrices and various Time-scales. The results we obtain here do extend, in part, aspects of the recent articles in that the Time-scale considered in this paper …


What Does A Scientist Look Like? Children's Perceptions Of Scientist Gender And Skin Tone, Angelina Joy, Channing J. Mathews, Adam Hartstone-Rose, Kelly Lynn Mulvaney Sep 2024

What Does A Scientist Look Like? Children's Perceptions Of Scientist Gender And Skin Tone, Angelina Joy, Channing J. Mathews, Adam Hartstone-Rose, Kelly Lynn Mulvaney

Purdue Center for Early Learning Faculty and Staff Publications

When asked to draw a scientist, children typically draw a gender stereotypical male representation; however, research has not yet assessed these representations in terms of scientist stereotypical skin tone. The current study examined children's (N = 69, 66.7% female, Mage = 7.60, SD = 2.13) scientist perceptions by analyzing both the gender and skin tone of their scientist drawings as well as stereotypical features represented (lab coats, scientific instruments, etc.). This study also examined how these perceptions as reflected in the drawings were related to children's explicit gender stereotypes and their science growth mindset. Boys were less likely …


Assessing Prevalence Of Blood Parasites And Ranaviruses In Hong Kong Freshwater Turtles, Julia Leung Sep 2024

Assessing Prevalence Of Blood Parasites And Ranaviruses In Hong Kong Freshwater Turtles, Julia Leung

Lingnan Theses (MPhil & PhD)

Blood parasites and ranaviruses are pathogens that impact freshwater turtles worldwide. Given that native turtle species in Hong Kong are already at a high risk of extinction, their survival becomes even more threatened in the event of a disease outbreak. However, prevalence of these pathogens among the native population in Hong Kong remains unstudied.

In this study, I aim to (1) obtain baseline prevalence data of blood parasites and ranaviruses in Hong Kong freshwater turtles, (2) compare different methods for detecting blood parasites and ranaviruses, (3) evaluate the applicability of using blood parasites as a wildlife forensic tool, assess and …


Domain-Based Nucleic-Acid Minimum Free Energy: Algorithmic Hardness And Parameterized Bounds, Erik D. Demaine, Elize Grizzell, Jayson Lynch, Ahmed Shalaby, Timothy Gomez, Markus Hecher, Robert Schweller, Damien Woods Sep 2024

Domain-Based Nucleic-Acid Minimum Free Energy: Algorithmic Hardness And Parameterized Bounds, Erik D. Demaine, Elize Grizzell, Jayson Lynch, Ahmed Shalaby, Timothy Gomez, Markus Hecher, Robert Schweller, Damien Woods

Computer Science Faculty Publications

Molecular programmers and nanostructure engineers use domain-level design to abstract away messy DNA/RNA sequence, chemical and geometric details. Such domain-level abstractions are enforced by sequence design principles and provide a key principle that allows scaling up of complex multistranded DNA/RNA programs and structures. Determining the most favoured secondary structure, or Minimum Free Energy (MFE), of a set of strands, is typically studied at the sequence level but has seen limited domain-level work. We analyse the computational complexity of MFE for multistranded systems in a simple setting were we allow only 1 or 2 domains per strand. On the one hand, …


Integrated Environmental Vulnerability Assessment And Adaptation Strategies For Coastal Areas Under Sustainable Development, Lien-Kwei Chien, Yu-Chi Li, Chia-Feng Hsu Sep 2024

Integrated Environmental Vulnerability Assessment And Adaptation Strategies For Coastal Areas Under Sustainable Development, Lien-Kwei Chien, Yu-Chi Li, Chia-Feng Hsu

Journal of Marine Science and Technology–Taiwan

This research focuses on the holistic management and environmental vulnerability of coastal areas in Taiwan within the framework of sustainable development. With economic and social growth gravitating towards coastal regions, the strain on the natural environment is increasing. Therefore, discovering a balance between economic progress and environmental conservation is paramount. To decipher the vulnerability of Taiwan's coastal zones, this study first defines ‘Integrated Environmental Vulnerability of Coastal Areas.’Key vulnerability factors were identified across environmental, social, and economic dimensions. Seven core determinants were determined using the Fuzzy Delphi method: biodiversity, coastal erosion, water pollution, population density, population aging, land utilization, and …


Evalution Of The Ability To Infer Tilt Angle And Size Distributions Of Fish Using A Broadband Scientific Echosounder Based On Simulation, Jing Liu Sep 2024

Evalution Of The Ability To Infer Tilt Angle And Size Distributions Of Fish Using A Broadband Scientific Echosounder Based On Simulation, Jing Liu

Journal of Marine Science and Technology–Taiwan

The biological information, such as species, size, and tilt angle, is crucial for converting the echo data into biomass information in acoustic surveys. Typically, the information can be obtained through trawl net sampling or underwater camera observations. However, both methods have some limitations. To overcome these limitations, scientists have utilized inversion methods with multi-frequency and broadband echosounders to derive biological information about fish, plankton, and krill. However, evaluating the reliability and accuracy of these inversion methods has been challenging due to the difficulty in obtaining accurate biological information. In this study, a numerical simulation method was used to generate fish …


A Forest Management Evaluation System For Small Private Forest Landowners, Pete Bettinger, Taeyoon Lee, Krista Merry, Daniel Drummond Sep 2024

A Forest Management Evaluation System For Small Private Forest Landowners, Pete Bettinger, Taeyoon Lee, Krista Merry, Daniel Drummond

Journal of Extension

When small private forest landowners have a need to address jointly economic and sustainability objectives, efficiency in both respects becomes important given limitations on the land, budget, time, and other resources that are available. The suite of forest management options available to a landowner may be vast and complex, therefore a tool to assist and inform their potential management activities can be of value. The eYield model was developed as an application (app) to assess forest management options on many different computing devices, from cellphones to desktop computers. Within eYield, a person can define a management situation, specify prices and …


Multimodal Mixing Convolutional Neural Network And Transformer For Alzheimer’S Disease Recognition, Junde Chen, Yun Wang, Adnan Zeb, M. D. Suzauddola, Yuxin Wen Sep 2024

Multimodal Mixing Convolutional Neural Network And Transformer For Alzheimer’S Disease Recognition, Junde Chen, Yun Wang, Adnan Zeb, M. D. Suzauddola, Yuxin Wen

Engineering Faculty Articles and Research

Early recognition of Alzheimer’s disease (AD) and its precursor state, mild cognitive impairment (MCI), is pivotal in interrupting the progression of the disease and providing suitable treatment. Recent development in deep learning techniques has drawn great research attention for improving the efficacy of AD recognition. However, numerous current methods solely utilize data from a single auxiliary domain, limiting their ability to harness valuable intrinsic insights from multiple domains. To cope with the challenge, this paper is devoted to establishing an innovative multimodal medical data fusion model, termed as MMDF, to perform Alzheimer’s disease recognition. Multimodal data including clinical records and …


Development And Benchmark Of Polarizable Models For Ions, Luke Landry Sep 2024

Development And Benchmark Of Polarizable Models For Ions, Luke Landry

Dissertations

Metalloproteins are ubiquitous in biology, playing crucial roles in diverse processes. Meanwhile, molecular simulations have become an important tool in scientific research. To accurately simulate metalloprotein systems, accounting for polarization and charge transfer effects is required. The fluctuating charge (FQ) model can effectively simulate the charge transfer effect, but the existing models often lack specificity for metalloproteins. In our research, a tailored FQ model for zinc-containing metalloproteins, leveraging the extended charge equilibration (EQeq) scheme, was introduced. CM5 charges were used as the target in our model parameterization, which offers advantages over RESP/CHELPG charges. Most notably, CM5 charges hold independence over …


Scientific History, Sampling Approach, And Physical Characterization Of The Camp Century Subglacial Material, A Rare Archive From Beneath The Greenland Ice Sheet, Paul R. Bierman, Andrew J. Christ, Catherine M. Collins, Halley M. Mastro, Juliana Souza, Pierre Henri Blard, Stefanie Brachfeld, Zoe R. Courville, Tammy M. Rittenour, Elizabeth K. Thomas, Jean Louis Tison, François Fripiat Sep 2024

Scientific History, Sampling Approach, And Physical Characterization Of The Camp Century Subglacial Material, A Rare Archive From Beneath The Greenland Ice Sheet, Paul R. Bierman, Andrew J. Christ, Catherine M. Collins, Halley M. Mastro, Juliana Souza, Pierre Henri Blard, Stefanie Brachfeld, Zoe R. Courville, Tammy M. Rittenour, Elizabeth K. Thomas, Jean Louis Tison, François Fripiat

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Basal materials in ice cores hold information about paleoclimate conditions, glacial processes, and the timing of past ice-free intervals, all of which aid understanding of ice sheet stability and its contribution to sea level rise in a warming climate. Only a few cores have been drilled through ice sheets into the underlying sediment and bedrock, producing limited material for analysis. The last of three Camp Century ice cores, which the U.S. Army collected in northwestern Greenland from 1963-1966 CE, recovered about 3.5 m of subglacial material, including ice and sediment. Here, we document the scientific history of the Camp Century …


Meta-Analysis Of Set-Based Multiple Phenotype Association Test Based On Gwas Summary Statistics From Different Cohorts, Lirong Zhu, Shuanglin Zhang, Qiuying Sha Sep 2024

Meta-Analysis Of Set-Based Multiple Phenotype Association Test Based On Gwas Summary Statistics From Different Cohorts, Lirong Zhu, Shuanglin Zhang, Qiuying Sha

Michigan Tech Publications

Genome-wide association studies (GWAS) have emerged as popular tools for identifying genetic variants that are associated with complex diseases. Standard analysis of a GWAS involves assessing the association between each variant and a disease. However, this approach suffers from limited reproducibility and difficulties in detecting multi-variant and pleiotropic effects. Although joint analysis of multiple phenotypes for GWAS can identify and interpret pleiotropic loci which are essential to understand pleiotropy in diseases and complex traits, most of the multiple phenotype association tests are designed for a single variant, resulting in much lower power, especially when their effect sizes are small and …


Methane Fluxes In Tidal Marshes Of The Conterminous United States, Ariane Arias-Ortiz, Jaxine Wolfe, Scott D. Bridgham, Sara Knox, Gavin Mcnicol, Brian A. Needelman, Julie Shahan, Ellen J. Stuart-Haëntjens, Lisamarie Windham-Myers, Patty Y. Oikawa, Dennis D. Baldocchi, Joshua S. Caplan, Margaret Capooci, Kenneth M. Czapla, R. Kyle Derby, Heida L. Diefenderfer, Inke Forbrich, Gina Groseclose, Jason K. Keller, Cheryl Kelley, Amir E. Keshta, Helena S. Kleiner, Ken W. Krauss, Robert R. Lane, Sarah Mack, Serena Moseman-Valtierra, Thomas J. Mozdzer, Peter Mueller, Scott C. Neubauer, Genevieve Noyce, Katrina V. R. Schäfer, Rebecca Sanders-Demott, Charles A. Schutte, Rodrigo Vargas, Nathaniel B. Weston, Benjamin Wilson, J. Patrick Megonigal, James R. Homquist Sep 2024

Methane Fluxes In Tidal Marshes Of The Conterminous United States, Ariane Arias-Ortiz, Jaxine Wolfe, Scott D. Bridgham, Sara Knox, Gavin Mcnicol, Brian A. Needelman, Julie Shahan, Ellen J. Stuart-Haëntjens, Lisamarie Windham-Myers, Patty Y. Oikawa, Dennis D. Baldocchi, Joshua S. Caplan, Margaret Capooci, Kenneth M. Czapla, R. Kyle Derby, Heida L. Diefenderfer, Inke Forbrich, Gina Groseclose, Jason K. Keller, Cheryl Kelley, Amir E. Keshta, Helena S. Kleiner, Ken W. Krauss, Robert R. Lane, Sarah Mack, Serena Moseman-Valtierra, Thomas J. Mozdzer, Peter Mueller, Scott C. Neubauer, Genevieve Noyce, Katrina V. R. Schäfer, Rebecca Sanders-Demott, Charles A. Schutte, Rodrigo Vargas, Nathaniel B. Weston, Benjamin Wilson, J. Patrick Megonigal, James R. Homquist

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Methane (CH4) is a potent greenhouse gas (GHG) with atmospheric concentrations that have nearly tripled since pre-industrial times. Wetlands account for a large share of global CH4 emissions, yet the magnitude and factors controlling CH4 fluxes in tidal wetlands remain uncertain. We synthesized CH4 flux data from 100 chamber and 9 eddy covariance (EC) sites across tidal marshes in the conterminous United States to assess controlling factors and improve predictions of CH4 emissions. This effort included creating an open-source database of chamber-based GHG fluxes (https://doi.org/10.25573/serc.14227085). Annual fluxes across chamber and EC sites averaged 26 ± 53 g CH4 …


Improving Ligand Pharmacokinetics Via Bioisosteric Substitution Of Amides With 1, 2, 3-Triazoles While Maintaining Dopamine D4 Receptor Selectivity And Potency, Mohammad Alkhatib Sep 2024

Improving Ligand Pharmacokinetics Via Bioisosteric Substitution Of Amides With 1, 2, 3-Triazoles While Maintaining Dopamine D4 Receptor Selectivity And Potency, Mohammad Alkhatib

Theses and Dissertations

Several neurophysiological functions, such as attention, cognition, and emotional regulation, are regulated by the binding of dopamine on G-Protein coupled receptors. D4Rs are mainly located in the prefrontal cortex and the hippocampus and are known to have a key role in decision-making, memory formation, cognition, and attention. Administration of D4Rs- selective ligands during the preclinical studies enhance the outcomes and the results in animal models suffering from neuropsychiatric disorders, including ADHD, substance use disorders (SUD), and Alzheimer's disease. Recently, we reported a group of D4R-selective ligands with different efficacies depending on their phenylpiperazine ring scaffold to illustrate D4R function during …


Rethinking Retrieval Augmented Fine-Tuning In An Evolving Llm Landscape, Nicholas Sager, Timothy Cabaza, Matthew Cusack, Ryan Bass, Joaquin Dominguez Sep 2024

Rethinking Retrieval Augmented Fine-Tuning In An Evolving Llm Landscape, Nicholas Sager, Timothy Cabaza, Matthew Cusack, Ryan Bass, Joaquin Dominguez

SMU Data Science Review

This study explores the utilization of Retrieval Augmented Fine-Tuning (RAFT) to enhance the performance of Large Language Models (LLMs) in domain-specific Retrieval Augmented Generation (RAG) tasks. By integrating domain-specific information during the retrieval process, RAG aims to reduce hallucination and improve the accuracy of LLM outputs. We investigate the use of RAFT, an approach that enhances LLMs by incorporating domain-specific knowledge and effectively handling distractor documents. This paper validates previous work, which found that RAFT can considerably improve the performance of Llama2-7B in specific domains. We also expand upon previous work into new state-of-the-art open-source models and other datasets with …


A Marine Knowledge System For Ocean Affairs: Integrating Data, Evaluating Usage, And Enabling Sustainable Marine Management, Yu-Jen Pan Sep 2024

A Marine Knowledge System For Ocean Affairs: Integrating Data, Evaluating Usage, And Enabling Sustainable Marine Management, Yu-Jen Pan

Journal of Marine Science and Technology–Taiwan

This study presents the evolution and assessment of the Marine Knowledge Education System (MKES), designed to improve user acceptance among students in professional marine science courses in Taiwan. The MKES leverages real-world maritime cases from the General Coast Guard Administration and is built upon existing technologies like cloud services, social networks, and data analysis tools. The technology acceptance model (TAM) provides the theoretical underpinning for the assessment of user confidence. Data was collected from 190 participants through purposive sampling. Path analysis confirmed all hypothesized relationships within the TAM with statistical significance (p < 0.001). Additionally, paired-sample t-tests revealed a significant increase in student acceptance of the MKES after integrating it into the marine science curriculum. These findings underscore the capacity of the MKES as a digital learning tool to enrich course pedagogy and improve student learning outcomes, thereby offering valuable support in advancing the education of professional marine managers.


The Foodpunk City: Advancing Portland's Food Security Through A Shared Ideology Of Adaptation & Resistance, Nickolas Hash Sep 2024

The Foodpunk City: Advancing Portland's Food Security Through A Shared Ideology Of Adaptation & Resistance, Nickolas Hash

Dissertations and Theses

Food injustice is a form of violence perpetrated by state and corporate actors against a constituency under their governing power, particularly impacting marginalized and impoverished communities. It denies individuals access to nutritious food, perpetuating cycles of poverty, inequality, physical health risks, and social exclusion. Grassroots movements have emerged to challenge dominant paradigms and advocate for food sovereignty, agroecology, and food anarchy. In Portland, the movement represents a nontraditional approach to food security that closely resembles the reactionary ideology of urban "punk" culture. Both groups prioritize community autonomy over food systems, sustainable agricultural practices, and resistance to oppressive structures that perpetuate …


A Revision Of Hong Kong Harvestmen : Biodiversity, Ecological Preferences And Geographical Distribution, Kai Teck Desmond Tan Sep 2024

A Revision Of Hong Kong Harvestmen : Biodiversity, Ecological Preferences And Geographical Distribution, Kai Teck Desmond Tan

Lingnan Theses (MPhil & PhD)

Opiliones, or harvestmen, is a common animal found throughout the world, there are currently over 6,650 species worldwide but the actual number is estimated to exceed 10,000, making it the third largest order in the class Arachnida. Despite its diversity, it is a rather understudied group. In Hong Kong, there are four described species, but the most recent relevant literature dates back to the at least the early 20th century. This thesis focuses on two common species found in Hong Kong: one previously described species (Heterobiantes geniculatus) and one new species (Pseudoleiobunum lutulentum sp. nov.). I …


Potential Nec2/Nek1 Inhibitor And Inh1 Analog N-[4-(2,4-Dimethylphenyl)-2-Thiazolyl]-4-Pyridinecarboxamide Via Hantzsch Thiazol Condensation, Robert E. Lee Sr, Isabella G. Mcdonald, Paige E. Heiple, Lukas D. Shelton Sep 2024

Potential Nec2/Nek1 Inhibitor And Inh1 Analog N-[4-(2,4-Dimethylphenyl)-2-Thiazolyl]-4-Pyridinecarboxamide Via Hantzsch Thiazol Condensation, Robert E. Lee Sr, Isabella G. Mcdonald, Paige E. Heiple, Lukas D. Shelton

Journal of the South Carolina Academy of Science

The potential active pharmaceutical ingredient (API), N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide (6) is a cancer cell metabolism mitosis inhibitor via the Nek2 and Hec1 enzymes. The three-step synthesis starts with the bromination of 1-(2,4-dimethylphenyl)ethan-1-one (1) using CuBr2 to produce 2-bromo-1-(2,4-dimethylphenyl)ethan-1-one (2) with a yield of 90%.[i],[ii],[iii] Followed by Hantzsch thiazol ring synthesis as (2) reacts with thiourea (3) and, resulting in 4-(2,4-dimethylphenyl)thiazol-2-amine (4)[iv] in 80% yield. Finally, isonicotinoyl chloride hydrochloride (5) and (4) reacted to form the amide (6).[v],[vi],[vii],[viii],[ix],[x] Characterization of the final product was determined …


Examination Of Oncogenic Effects Of Environmental Pollutants, Andrew Ackerman, Matthew Behling, Brock Earley, Janay Vacharasin Sep 2024

Examination Of Oncogenic Effects Of Environmental Pollutants, Andrew Ackerman, Matthew Behling, Brock Earley, Janay Vacharasin

Journal of the South Carolina Academy of Science

Chemical byproducts produced by surrounding industrial complexes have polluted the local estuaries of Georgetown, South Carolina for several decades1. Previous studies completed by the EPA and SCDNR showed that the estuaries contained carcinogenic pollutants released from the local manufacturing plants1. One of the mentioned pollutants was dioxins which are produced during the paper bleaching process2. Dioxins are highly toxic compounds that have various carcinogenic effects on the organisms that inhabit the area. These previous studies were conducted over thirty years ago. Therefore, a current study to determine if chemical byproducts are contaminating local estuaries …


Striatal Beat Frequency Interval Timing Model With Microgravity Stressor, Jason Michael Fitzgerald, Sorinel Oprisan Sep 2024

Striatal Beat Frequency Interval Timing Model With Microgravity Stressor, Jason Michael Fitzgerald, Sorinel Oprisan

Journal of the South Carolina Academy of Science

The Striatal Beat Frequency (SBF) model of interval timing uses frontal cortex (FC) neural oscillations to record the state of the brain at the reinforcement time Tc during fixed interval (FI) procedures in the long-term memory (LMEM). The state of the FC oscillators at any given time is stored in a short-term memory (SMEM) buffer. The SBF model uses the spiny neurons of the basal ganglia (BG) as coincidence detectors to produce beats between the content of the SMEM and LMEM. Across multiple species that can perform interval timing, there are two invariant properties: (a) the timing is precise, and …