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Molecular Interaction Between Nitric Oxide And Ryanodine Receptors Of Skeletal And Cardiac Sarcoplasmic Reticulum, Guy Salama, Elizaveta V. Menshikova, Jonathan J. Abramson

Physics Faculty Publications and Presentations

In striated muscle, the sarcoplasmic reticulum (SR) is the major storage compartment of intracellular Ca2+ that controls cytosolic free Ca2+ (Cai) and developed force by sequestering and releasing Ca2+ during each contraction. Ca2+ release from the SR occurs through high-conductance Ca2+ release channels or ryanodine receptors (RyR), which are regulated by various signaling processes. Over the last 15 years, there has been a growing consensus that critical sulfhydryl sites on RyRs can be oxidized and reduced, respectively, to open and close the release channels. The pharmacological actions of various classes of sulfhydryl reagents have demonstrated the existence of hyperreactive thiols …

1998-1999 Monitoring Strategy, Kentucky River Basin Management Unit, L. Ormsbee, G. Epp, E. Caudill, Lee Colten

KWRRI Research Reports

During the fall of 1997 and spring of 1998 about 40 individuals and more than 30 organizations and agencies provided input into the development of a monitoring strategy for the Kentucky River basin under the Kentucky Watershed Management Framework. In addition to the agencies that were able to commit resources to the monitoring effort, citizen input was sought in the design of the strategy. Citizen monitoring efforts are also providing valuable information in many portions of the state. The intent of the coordinated planning process was to carefully consider agency resources and capabilities, taking into account where and when each …

Kentucky Water Resources Research Institute Annual Technical Report Fy 1999, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY 1999 Annual Technical Report for Kentucky consolidates the reporting requirements of the Section 104(b) base grant and regional competitive grant awards in a single technical report which includes: 1) a synopsis of each ongoing research project and each research project completed during the period, 2) a list of related reports published, 3) a brief description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable achievements and awards during the year. The activities supported by Section 104 (b) and the required matching funds are interwoven into the Kentucky Water Resources ResearchInsitute's …

Contents

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Examination Of Student-Active Learning Practices In A College/Middle School Educational Collaboration, S. Prattis, I. Czerwiec

Journal of Mathematics and Science: Collaborative Explorations

A college and middle school student teaching collaboration was developed to interest more college students in teaching K-12 science, to enhance diversity among K-16 teaching faculties, and to inspire the K-12 students to expand their knowledge beyond their classroom curriculum. To assess our results, we used a modified Likert survey instrument and self-reflective analysis in middle school and college students, respectively. Overall, middle school students expressed satisfaction in the science learning in which they participated. In addition, college students reported that they learned specific content when made responsible for teaching material to younger students. Collaborative projects such as this one …

The Stcc Science Teaching Intern Project, N. Rapoport

Journal of Mathematics and Science: Collaborative Explorations

The Springfield Technical Community College (STCC) Science Teaching Intern Project was implemented as a pilot study to give community college students an opportunity to experience science teaching. At the same time, it provided seventh graders in inner city middle schools opportunities to interact with college students and to take advantage of science resources not usually available to them. Interns attended weekly meetings and participated in an all-day science field trip at the college. Most participants also made observations in a middle school science classroom and presented a science activity in the classroom. Not only did the project provide a partnership …

Project- And Group-Based Learning Of Junior Writing In Biology, J. G. Kunkel

Journal of Mathematics and Science: Collaborative Explorations

Writing in Biology, part of the Junior Writing Program, is inherently a project-based learning course. After a Science, Technology, Engineering, and Mathematics Teacher Education Collaborative (STEMTEC) workshop, the course was thoroughly revised. Each of six projects was modified to increase student-active and group participation. Base groups with a balanced experience constitution are established using voluntary ordering and random assignment. A walk-around during the initial meeting serves to establish bonding within the base groups. Random groups are used within exercises to stimulate student interaction and familiarity with ad hoc group cooperation. Digital images of, and by, students are used to encourage …

Alternative Modes For Teaching Mathematical Problem Solving: An Overview, H. A. Peelle

Journal of Mathematics and Science: Collaborative Explorations

Various modes are proffered as alternatives for teaching mathematical problem solving. Each mode is described briefly, along with general purposes, advantages and disadvantages. Combinations of modes are suggested; general issues identified; recommendations offered; and feedback from teachers summarized.

Journal Of Mathematics And Science: Collaborative Explorations

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Student Work Section, R. Howard

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

A Computational Approach To Determining Stability Constants For Transition Metal Ion Complexes, Jason St. Clair

Honors Theses

The complexation of metal ions in natural waters plays a critical role in defining the metal's biogeochemistry, Numerous investigators have used various experimental techniques to measure complexation constants in the laboratory, but many constants are still poorly undefined or have yet to be investigated due to the difficulty of some of the experiments. A computational approach to obtaining these constants for complexes of Fe(lII), Fe(D), Cr(lli), Cu(lI), Zn(II), and Cd(II) was explored with varying degrees of success. Calculated Gibbs Free Energies were compared to experimental stability constants. Calculations were performed using Spartan's DFT package at the pEP level and with …

Cisplatin Interstrand Cross-Linking Of Defined Sequence Nucleosomal Dna, Erin Elizabeth Wilkes

Honors Theses

DNA interstrand cross-linking agents have been recognized for many years to be powerful antitumor chemotherapeutics. While the interactions between free DNA and many anticancer drugs have been explored extensively, there is less infonnation available about these interactions with nucleosomal DNA. Nitrogen mustards have been reported to exhibit relatively similar cross-linking sites and efficiencies of binding in free and nucleosomal DNA, but mitomycin C exhibits markedly reduced cross-linking near the center of nucleosomal DNA. This current study focuses on cisplatin interstrand cross-linking of the 154 base pair 55 rRNA gene fragment of Xenopus borealis reconstituted with histones from chicken erythrocytes. The …

A Catechol Approach To Natural Product Synthesis, Michelle E. Weber

Honors Theses

This research has focused on the total synthesis of the iron--chelating natural product 1-(2,3-hydroxyphenyl)-4-methoxy-I-butanone. An extract of the iron-cleficient fungus Gleophyllwn lraebeum, this molecule is thought to bind to Fe3+ in a hexacoordinate system to aid in transport through cell walls in order to help regulate iron levels in such iron-deficient fungi. Since the proposed structure of the molecule is based only on the spectral data of a very small sample, our hope is to synthesize and confirm its structure as the extract of the brown rot fungus. We have developed a relatively short retrosynthesis for our work on this …

Interactions Of Ti(Iv) And Sn(Iv) Organometallic Complexes With Double-Stranded Dna, Katherine Macdonald Davies

Honors Theses

In order to understand further the interactions that exist between specific organometallic complexes and DNA, reactions of double-stranded calf-thymus DNA with bis(cyclopentadienyl)titanium dichloride [Cp₂TiC1₂] (TDC), bis(t-butylcyclopentadienyl)titanium dichloride [(C₄H₉Cp)₂TiC1₂] (r-butyl TDC), bis(i-propylcyclopentadienly)titanium dichloride [(C₃H₆Cp)2TiCl₂ a-propyl mc), bis(pentamethylcyclopentadienyl) titanium dichloride [(Cp"₂TiC1₂ (pentarnethyl TDC), triphenyltin chloride (Ph₃SnCl), diphenylrin dichloride (Ph₂SnC1₂) , and triphenyltin acetate (Ph₃SnOAc) were performed. The goal of this research is to establish how the fundamental structure and composition of these compounds determine the effecti veness of their DNA interactions. Each metal compound was incubated with calf thymus DNA at several metal: DNA ratios and reactions were maintained at 37°C at …

Sistem Maklumat Multimedia Batu Karang Malaysia (Mcris), Shamsudin Suhainah

Student Works (2000-2009)

Projek Ilmiah merupakan syarat wajib kepada para pelajar yang mengambil kursus Sarjana Muda Teknologi Maklumat (Pengurusan) di Universiti Malaya yang ingin menamatkan pengajian mereka. Projek ini terbahagi kepada dua bahagian iaitu Projek Ilmiah Tahap Awal (WXET 3181) dan Projek Ilmiah Tahap Akhir (WXET 3182). Pelajar dibenarkan memilih tajuk sendiri. Maka, saya telah memilih tajuk Sistem Maklumat Multimedia Batu Karang di Malaysia (McRis) di bawah seliaan En. Mustaffa Kamal dan Dr. Mazliza sebagai moderator. McRis merupakan satu sistem maklumat yang berkaitan dengan batu karang yang terdapat di firdausi taman laut kita seperti jenis-jenisnya dan sedikit penerangan yang disertakan dengan gambar yang …

Managing The Acidity Of Abandoned Water Filled Coal Mining Voids In Collie (Western Australia) Using Organic Matter, Scott A. Thompson

Theses: Doctorates and Masters

The effectiveness of using organic matter additions to increase pH in abandoned water filled coal mining voids in Collie was investigated. Previous studies have demonstrated that passing acidic drainage through organic matter increased the waters pH. Laboratory trials using intact sediment cores (collected from Ewington, Collie, Western Australia) were used to assess the effects of additions of hay, manure and mulched vegetation on pH, nutrients an sulphate levels. In a series of experiments the effect of different quantities of organic material, sulphate reducing bacterial inoculations and alkalinity generation were measured. A subsequent field experiment was conducted to examine the impact …

Development, Management And Economy Of Show Caves, Arrigo A. Cigna, Ezio Burri

International Journal of Speleology

The problems concerning the development of show caves are here considered by taking into account different aspects of the problem. A procedure to carry out an Environmental Impact Assessment (EIA) has been established in the last decade and it is now currently applied. Such an assessment starts with a pre-operational phase to obtain sufficient information on the undisturbed status of a cave to be developed into a show cave. Successively a programme for its development is established with the scope to optimise the intervention on the cave at the condition that its basic environmental parameters are not irreversibly modified. The …

State Of The Fisheries Report 1999/2000, J. W. Penn, Fisheries Western Australia

Status Reports of the Fisheries and Aquatic Resources

The State of the Fisheries document is designed as an essential supplement to the Annual Report to Parliament and provides a more detailed level of information to support the agency's non-financial performance measures.

By summarising management changes, compliance activities and research data such as landings, effort, catch rates, stock assessment and breeding stock levels, this document provides a valuable reference point for Western Australian fisheries of major importance to the commercial, recreational and aquaculture sectors. Information relevant to Fisheries WA's Fish and Fish Habitat Protection Program is also provided.

The report indicates that overall the major fish stocks which support …

Theories Of The Origin And Early Evolution Of Life, David A. Dewitt

Faculty Publications and Presentations

After the theory of spontaneous generation was discredited, only religious explanations were offered to explain the origin of life. Alexander Oparin (1894-1980), an atheist, suggested that natural chemical reactions produced biological molecules that came together to form the first living thing. Later, Stanley Miller tested this hypothesis and produced chemical "building blocks" but not life itself. In spite of much progress, there is still no clear consensus on how life originated on Earth. Some scientists are even looking to outer space for the origin of life.

Test 1778: John Deere 8410t And 8420t Diesel 16-Speed, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA

The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data.

EXPLANATION OF THE TEST PROCEDURES

Purpose

The purpose of …

Test 1781: White 8510 Diesel 18-Speed, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA

The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data.

EXPLANATION OF THE TEST PROCEDURES

Purpose

The purpose of …

Test 1787: John Deere 7610 Powrquad Diesel 20-Speed (Chassis S/N Rw7610r030002 And Higher), Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA

The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data.

EXPLANATION OF THE TEST PROCEDURES

Purpose

The purpose of …

Test 1776: John Deere 8310t Diesel 16-Speed, Nebraska Tractor Test Lab

Nebraska Tractor Tests

ABOUT THE TEST REPORT AND USE OF THE DATA

The test data contained in this report are a tabulation of the results of a series of tests. Due to the restricted format of these pages, only a limited amount of data and not all of the tractor specifications are included. The full OECD report contains usually about 30 pages of data and specifications. The test data were obtained for each tractor under similar conditions and therefore, provide a means of comparison of performance based on a limited set of reported data.

EXPLANATION OF THE TEST PROCEDURES

Purpose

The purpose of …

Learning On The Halfshell, M. H. Duffey, C. Roberts

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Diversity Education For Pre-Service Science Teachers, D. R. Sterling

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Climbing The Ladder From Ninth Grade To College: A Career Ladder Program At The Science Museum Of Virginia, A. Thomas, D. Hagan

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Mathematics In Hands-On Science For Liberal Arts Students, M. I. Sobel

Journal of Mathematics and Science: Collaborative Explorations

We describe a number of experiments from the courses called, General Science 9, part of the science program for elementary education majors at Brooklyn College. These courses provide hands-on learning experiences for students who are insecure and weak in science and mathematics. Quantitative thinking is a central element in most of the students’ work. Mathematics is taught in a concrete and intuitive way, as a direct outgrowth of their needs; first, in analysis of data, and second, in discovering underlying theory. The science program has been developed through cooperation among faculty from the School of Education and the science departments.

Active Learning In Sophomore Mathematics: A Cautionary Tale, M. Eisenberg

Journal of Mathematics and Science: Collaborative Explorations

Math 245: Multivariate Calculus, Linear Algebra, and Differential Equations with Computer I is the first half of a year-long sophomore sequence that emphasizes the subjects' interconnections and grounding in real-world applications. The sequence is aimed primarily at students from physical and mathematical sciences and engineering. In Fall, 1998, as a result of my affiliation with the Science, Technology, Engineering, and Mathematics Teacher Education Collaborative (STEMTEC), I continued and extended previously-introduced reforms in Math 245, including: motivating mathematical ideas with real-world phenomena; student use of computer technology; and, learning by discovery and experimentation. I also introduced additional pedagogical strategies for more …

The Effects Of Acid Deposition, B. Proffitt

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

The Use Of Project-Based Learning In A Technology Course For Math And Science Teachers, B. Murfin

Journal of Mathematics and Science: Collaborative Explorations

In this project, pre- and in-service math and science teachers used project-based learning to learn the complex skills involved in integrating technology into math and science teaching. The teachers in the course E36.1002: Microcomputer Applications in Math and Science Instruction in the Department of Teaching & Learning at New York University developed a four-week curriculum that integrates math, science, and technology using a common theme chosen by the teachers. The program has received very positive feedback from all participants and may be expanded in the future. Some recommendations are provided on how field experience in teaching with technology can be …