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Size Dependent Translocation And Fetal Accumulation Of Gold Nanoparticles From Maternal Blood In The Rat, Manuela Semmler-Behnke, Jens Lipka, Alexander Wenk, Martin Schaeffer, Furong Tian, Gunter Schmid, Gunter Oberdorster, Wolfgang Kreyling

Articles

There is evidence that nanoparticles (NP) cross epithelial and endothelial body barriers. We hypothesized that gold (Au) NP, once in the blood circulation of pregnant rats, will cross the placental barrier during pregnancy size-dependently and accumulate in the fetal organism by 1. transcellular transport across the hemochorial placenta, 2. transcellular transport across amniotic membranes 3. transport through ~20 nm wide transtrophoblastic channels in a size dependent manner. The three AuNP sizes used to test this hypothesis are either well below, or of similar size or well above the diameters of the transtrophoblastic channels.

The Total Picture: Multiple Chemical Exposures To Pregnant Women In The Us – An Nhanes Study Of Data From 2003 Through 2010, Teri Cabana

Theses and Dissertations

INTRODUCTION: Chemical exposures to US pregnant women have been shown to have adverse health impacts on both mother and fetus. A prior paper revealed that US pregnant women in 2003-2004 had widespread exposure to multiple chemicals. The goal of this research is to examine how environmental chemical exposures to US pregnant women have changed from 2003 to 2010 and to look further at the extent of simultaneous exposure to multiple chemicals in US pregnant women using biomonitoring data available through NHANES (the National Health and Nutritional Examination Survey). METHODS: Using available NHANES data from the following cycles (2003-2004, 2005-2006, 2007-2008, …

An Efficient Synthesis Of Some New Bisbenzimidazoles Via Microwave Technique, Bahi̇tti̇n Kahveci̇, Nesri̇n Karaali̇, Fati̇h Yilmaz, Emre Menteşe

Turkish Journal of Chemistry

2,2'-[1,4 (1,3)-Phenylenedi(methylene)]bis-1H-benzimidazole derivatives were obtained from the reaction of 1,4- or (1,3)-bisiminoester hydrochloride and o-phenylenediamine derivatives under microwave irradiation. Ester and hydrazide derivatives were prepared from a free NH group. This practical method revealed good results for yield, reaction time, and quick isolation of products.

Phytoplankton And Nutrient Dynamics In A Tidally Dominated Eutrophic Estuary: Daily Variability And Controls On Bloom Formation, Ryan E. Morse, Margaret R. Mulholland, Todd A. Egerton, Harold G. Marshall

OES Faculty Publications

To better understand nutrient dynamics and factors that promote the initiation of algal blooms, the Lafayette River, a tidal subestuary of Chesapeake Bay that experiences seasonal algal blooms, was sampled daily for a period of 54 d in the fall of 2005. Three phytoplankton blooms (chl a concentrations exceeding twice the average of monthly measurements from 2000 to 2009) occurred during this period: a mixed bloom of Akashiwo sanguinea and Gymnodinium sp., a monospecific Skeletonema costatum bloom, and a monospecific Gymnodinium sp. bloom. Over the sampling period, nutrient concentrations increased following precipitation events and were elevated between bloom periods but …

Time-Dependent Regulation Of Apoptosis By Aen And Bax In Response To 2-Aminoanthracene Dietary Consumption, Worlanyo E. Gato, Dale B. Hales, Stacey R. Mcgee, Jay C. Means

Chemistry: Faculty Publications (1990-2023)

Background/Objective: The modulation of the toxic effects of 2-aminoanthracene (2AA) on the liver by apoptosis was investigated. Fisher-344 (F344) rats were exposed to various concentrations of 2AA for 14 and 28 days. The arylamine 2AA is an aromatic hydrocarbon employed in manufacturing chemicals, dyes, inks, and it is also a curing agent in epoxy resins and polyurethanes. 2AA has been detected in tobacco smoke and cooked foods.

Methods: Analysis of total messenger ribonucleic acid (mRNA) extracts from liver for apoptosis-related gene expression changes in apoptosis enhancing nuclease (AEN), Bcl2-associated X protein (BAX), CASP3, Jun proto-oncogene (JUN), murine double minute-2 p53 …

Speciation Of Chromium By The Combination Of Dispersive Liquid--Liquid Microextraction And Microsample Injection Flame Atomic Absorption Spectrometry, Yunusemre Ünsal, Mustafa Tüzen, Mustafa Soylak

Turkish Journal of Chemistry

A microextraction procedure was established for the speciation of total Cr, Cr(III), and Cr(VI). Sudan blue II was used as a ligand for speciation works. Some factors affecting the recoveries of chromium species, including type of extraction and dispersive solvents, pH, ligand amount, extraction time, and matrix ions, were examined. Optimum values for the dispersive liquid--liquid microextraction method were pH 6, LOD 0.34 \mu g L^{-1}, and preconcentration factor 400. Chromium(III) was quantitatively recovered under optimal conditions, while the recovery of chromium(VI) was below 10%. The relative standard deviation for Cr(III) determinations for the 10-replicate measurement of 0.3 \mu g …

Part I: In-Situ Fluorometric Quantification Of Microalgal Neutral Lipids Part Ii: Thermal Degradation Behavior Of Investment Casting Polymer Patterns, Hongfang Zhao

Doctoral Dissertations

"Research described in this dissertation covers two topics. Part-I is focused on in-situ determination of neutral lipid content of microalgae using a lipophilic fluorescent dye. The traditional Nile red stain-based method for detecting microalgal intracellular lipids is limited due to varying composition and thickness of rigid cell walls. In this study, the addition of dilute acid and heating of solution, were found to greatly enhance staining efficiency of Nile red for microalgal species evaluated. Oil-in-water (O/W) microemulsion stabilized by a non-ionic surfactant was employed as a pseudo-standard that mimics lipid-bearing microalgal cells suspended in water. The average neutral lipid contents …

Investigation Of Angiogenic Effects Of Bioactive Borate Glass Microfibers And Beads In A Rodent Model, Richard Jeffrey Watters

Masters Theses

"The primary objective of this research project was to evaluate the effects of three different compositions of bioactive glass microfibers (45S5, 13-93B3, and 13-93B3Cu) and bioactive glass beads (13-93, 13-93B3, and 13-93B3Cu) on angiogenesis in subcutaneous tissue in the SKH1 'hairless' mouse. Microvascular responses to the bioactive glass implants were investigated via three experimental approaches: noninvasive vital imaging of microvasculature in dorsal skin windows; quantitative histomorphometry of microvascular densities; and quantitative PCR measurements of mRNA expression of pro-angiogenic cytokines VEGF and FGF-2. The live imaging of dorsal skin window preparations in the hairless SKH1 showed the formation of a halo-like …

Economic Valuation Of The Mortality Benefits Of A Regulation On So2 In 20 European Cities, Olivier Chanel, Susann Henschel, Patrick J. Goodman, Antonis Analitis, Richard W. Atkinson, Alain Le Tertre, Ariana Zeka, Sylivia Medina

Articles

Background: Since the 1970s, legislation has led to progress in tackling several air pollutants. We quantify the annual monetary benefits resulting from reductions in mortality from the year 2000 onwards following the implementation of three European Commission regulations to reduce the sulphur content in liquid fuels for vehicles. Methods: We first compute premature deaths attributable to these implementations for 20 European cities in the Aphekom project by using a two-stage health impact assessment method. We then justify our choice to only consider mortality effects as short-term effects. We rely on European studies when selecting the central value of …

Genetic Algorithm With Logistic Regression For Prediction Of Progression To Alzheimer's Disease, Piers Johnson, Luke Vandewater, William Wilson, Paul Maruff, Greg Savage, Petra Graham, Lance S. Macaulay, Kathryn A. Ellis, Cassandra Szoeke, Ralph N. Martins, Christopher Rowe, Colin L. Masters, David Ames, Ping Zhang

Research outputs 2014 to 2021

Assessment of risk and early diagnosis of Alzheimer's disease (AD) is a key to its prevention or slowing the progression of the disease. Previous research on risk factors for AD typically utilizes statistical comparison tests or stepwise selection with regression models. Outcomes of these methods tend to emphasize single risk factors rather than a combination of risk factors. However, a combination of factors, rather than any one alone, is likely to affect disease development. Genetic algorithms (GA) can be useful and efficient for searching a combination of variables for the best achievement (eg. accuracy of diagnosis), especially when the search …

Cloud Security Meets Telemedicine, Michael N. Johnstone

Research outputs 2014 to 2021

Medical systems are potentially one domain where security is seen as an impediment to patient care and not as an essential part of a system. This is an issue for safety-critical systems where reliability and trust are essential for successful operation. Cloud computing services offer a seamless means to allow medical data to be transferred from patient to medical specialist, whilst maintaining security requirements. This paper uses a case study to investigate the use of cloud computing in a mobile application to assist with diagnostics for patients with Parkinson Disease. It was found that the developers of the app ignored …

Mechanisms And Ecological Role Of Carbon Transfer Within Coastal Seascapes, Glenn A. Hyndes, Ivan Nagelkerken, Rebecca J. Mcleod, Rod M. Connolly, Paul S. Lavery, Mathew A. Vanderklift

Research outputs 2014 to 2021

Worldwide, coastal systems provide some of the most productive habitats, which potentially influence a range of marine and terrestrial ecosystems through the transfer of nutrients and energy. Several reviews have examined aspects of connectivity within coastal seascapes, but the scope of those reviews has been limited to single systems or single vectors. We use the transfer of carbon to examine the processes of connectivity through multiple vectors in multiple ecosystems using four coastal seascapes as case studies. We discuss and compare the main vectors of carbon connecting different ecosystems, and then the natural and human-induced factors that influence the magnitude …

Assessment Of Habitat Quality For Red Snapper, Lutjanus Campechanus, In The Northwestern Gulf Of Mexico: Natural Vs. Artificial Reefs, Brittany Dawn Schwartzkopf

LSU Master's Theses

Habitat quality of natural and artificial reefs for red snapper (Lutjanus campechanus) in the northwestern Gulf of Mexico (Gulf) is important as this area is home to the majority of the Gulf’s artificial reef system, in the form of oil and gas platforms, in addition to the largest extent of high vertical relief natural habitat. This study sought to assess habitat quality of natural reefs of varying habitat complexity and an artificial reef complex located on the LA continental shelf. Habitat quality was assessed by comparing red snapper diets and foraging patterns, and nutritional condition using the liver-somatic index (LSI) …

Determination Of Predominant Species Of Oil-Degrading Bacteria In The Oiled Sediment In Barataria Bay, Louisiana, Lauren Nicole Navarre

LSU Master's Theses

The effects of the Deepwater Horizon (DWH) oil spill on the bacterial communities in coastal sediments are relatively known but few studies have been published evaluating the impacts of the spill on oil-degrading bacterial populations in the salt marsh sediments of Barataria Bay, Louisiana. The aims of this study were to determine the effects of the oil spill on the microbial community in Barataria Bay, Louisiana through the determination of predominate species of oil-degrading bacteria in marsh sediments, and to determine how well certain bacterial isolates can degrade crude oil in the region by taking samples from three areas of …

Prevalence Of Blue Crab (Callinectes Sapidus) Diseases, Parasites, And Symbionts In Louisiana, Holly Rogers

LSU Master's Theses

Research on blue crab diseases, parasites, and symbionts has been sporadic in the Gulf of Mexico. Understanding the prevalence of diseases, parasites, and symbionts is important for managers to set informed regulations for the commercial industry and to understand the impacts of environmental disasters on aquatic animal health. The objective of this research was to determine the prevalence of Lagenophrys callinectes, Urosporidium crescens, Hematodinium perezi, Loxothylacus texanus, reo-like virus (RLV), shell rot, and Vibrio spp. in crabs collected from four coastal locations and four shedding facilities in 2013 and the beginning of 2014. Additionally, I determined the prevalence of white …

Methods For The Characterization Of Deep-Sea Benthic Megafauna In The Vicinity Of The Deepwater Horizon Macondo Well, Stephanie Marie Sharuga

LSU Doctoral Dissertations

Soft-sediment benthic environments are amongst the largest marine ecosystems in the world and play important roles in many ecosystem functions. In recent years, exploitation of resources and unintentional impacts on deep-sea benthic environments has increased. The Deepwater Horizon oil spill of 2010 in the northern Gulf of Mexico (GoM) represented a prime example of this. The oil spill not only highlighted deficiencies of data and information on baseline conditions, but also represented an opportunity to learn more and develop better methods for the future. Deep-sea imaging platforms such as autonomous underwater vehicles (AUVs) and remotely operated vehicles (ROVs) have been …

Synthesis And Analysis Of Copper Beta-Diketonate Complexes, Jonathan Stephen Casey

LSU Master's Theses

This research addresses the synthesis and characterization of Cu(II) complexes of silicon-based multidentate β-diketonate ligands. The possible products of the synthesis include (where L represents the coordinated ligand) cube Cu12L8, decahedron Cu24L16, and dodecahedron Cu30L20. This study aims to determine the structure of these discrete molecules, which may have applications in drug delivery, fuel storage, and chemical retention. Different techniques were involved in the characterization of Cu(II) complexes: Electrospray Ionization Time of Flight Mass Spectrometry (ESI-TOF MS), Atomic Force Microscopy (AFM) and Analytical Ultracentrifugation (AUC). In ESI-TOF MS, the exact mass of the molecules was attempted to be determined by …

Emergence Of Algal Blooms: The Effects Of Short-Term Variability In Water Quality On Phytoplankton Abundance, Diversity, And Community Composition In A Tidal Estuary, Todd A. Egerton, Ryan E. Morse, Harold G. Marshall, Margaret R. Mulholland

OES Faculty Publications

Algal blooms are dynamic phenomena, often attributed to environmental parameters that vary on short timescales (e.g., hours to days). Phytoplankton monitoring programs are largely designed to examine long-term trends and interannual variability. In order to better understand and evaluate the relationships between water quality variables and the genesis of algal blooms, daily samples were collected over a 34 day period in the eutrophic Lafayette River, a tidal tributary within Chesapeake Bay's estuarine complex, during spring 2006. During this period two distinct algal blooms occurred; the first was a cryptomonad bloom and this was followed by a bloom of the mixotrophic …

Proceedings Of The 1st Annual Cuny Games Festival, Robert O. Duncan, Joe Bisz, Francesco Crocco, Carlos Hernandez, Kathleen Offenholley, Leah Potter, Maura A. Smale, Cuny Games Network

Publications and Research

Proceedings of the CUNY Games Conference, held from January 17-18, 2014, at the CUNY Graduate Center and Borough of Manhattan Community College.

Topics in Game Design - Teaching with Virtual and Augmented Realities - Writing with Games - Breaking the Magic Circle: Games & Real Life - Interactive Game Design (What's Your Game Plan? - Designing Ethical Games - Games and Gender - Gaming English Language and Literature - Game, Narrative, Literacy - Teaching with Games - Games, Storytelling, and Narrative - Games and STEM - Learning by Design - Students as Game Designers - Experiencing Reality in Popular Games …

Benthic And Pelagic Pathways Of Methylmercury Bioaccumulation In Estuarine Food Webs Of The Northeast United States, Celia Y. Chen, Mark E. Borsuk, Deenie M. Bugge, Terill Hollweg

Dartmouth Scholarship

Methylmercury (MeHg) is a contaminant of global concern that bioaccumulates and bioamagnifies in marine food webs. Lower trophic level fauna are important conduits of MeHg from sediment and water to estuarine and coastal fish harvested for human consumption. However, the sources and pathways of MeHg to these coastal fisheries are poorly known particularly the potential for transfer of MeHg from the sediment to biotic compartments. Across a broad gradient of human land impacts, we analyzed MeHg concentrations in food webs at ten estuarine sites in the Northeast US (from the Hackensack Meadowlands, NJ to the Gulf of Maine). MeHg concentrations …

Improving The Representation Of Roots In Terrestrial Models, Erica A.H. Smithwick, Melissa S. Lucash, M. Luke Mccormack, Gajan Sivandran

Environmental Science and Management Faculty Publications and Presentations

Root biomass, root production and lifespan, and root-mycorrhizal interactions govern soil carbon fluxes and resource uptake and are critical components of terrestrial models. However, limitations in data and confusions over terminology, together with a strong dependence on a small set of conceptual frameworks, have limited the exploration of root function in terrestrial models. We review the key root processes of interest to both field ecologists and modelers including root classification, production, turnover, biomass, resource uptake, and depth distribution to ask (1) what are contemporary approaches for modeling roots in terrestrial models? and (2) can these approaches be improved via recent …

Occurrence Of Synthetic Amino-Polycarboxylate Chelating Compounds In Oregon Surface Waters, Nathan A. Hersey

Civil and Environmental Engineering Master's Project Reports

Cation sequestering compounds are contained in many industrial, commercial and personal care products. The most widely used chelating agents, EDTA and DTPA, are commonly found in natural and industrial settings. When chelating compounds are present, the activity and transport of metal cations in the environment and the uptake of metals in natural systems can be affected. Surface water samples from across the United States were analyzed, as well as local collection and analysis of surface waters and wastewater treatment plant effluent from around Northwest Oregon. Results indicate presence of synthetic chelating compounds in areas with human activity, and absence in …

A Survey Of Image Processing Techniques For Agriculture, Lalit Saxena, Leisa Armstrong

Research outputs 2014 to 2021

Computer technologies have been shown to improve agricultural productivity in a number of ways. One technique which is emerging as a useful tool is image processing. This paper presents a short survey on using image processing techniques to assist researchers and farmers to improve agricultural practices. Image processing has been used to assist with precision agriculture practices, weed and herbicide technologies, monitoring plant growth and plant nutrition management. This paper highlights the future potential for image processing for different agricultural industry contexts.

Infrared Vibrational Spectroscopy Analysis Of Selected Biomolecules, Busra Ergul

Theses and Dissertations

Fourier transform infrared (FTIR) spectroscopy is a useful tool to examine biological molecules for noninvasive measurements. This research has focused on the determination of concentrations of four important biomolecules, glucose, gluconic acid, hydrogen peroxide (H2O2), and dopamine by FTIR. It is crucial to determine blood glucose levels for diabetes diagnosis. H2O2 is an important biomolecule having implications in aging and aging related diseases. Gluconic acid is important in food and pharmaceutical industries, and dopamine plays a key role in brain activity. In this work, first, glucose, gluconic acid, and H2O2 in aqueous solutions have been studied by using FTIR. Standard …

Primary Care-Based Educational Interventions To Decrease Risk Factors For Metabolic Syndrome For Adults With Major Psychotic And/Or Affective Disorders: A Systematic Review, Cynthia Nover, Sarah S. Jackson

Epidemiology Faculty Publications

Background

Individuals with major psychotic and/or affective disorders are at increased risk for developing metabolic syndrome due to lifestyle- and treatment-related factors. Numerous pharmacological and non-pharmacological interventions have been tested in inpatient and outpatient mental health settings to decrease these risk factors. This review focuses on primary care-based non-pharmacological (educational or behavioral) interventions to decrease metabolic syndrome risk factors in adults with major psychotic and/or affective disorders.

Methods

The authors conducted database searches of PsychINFO, MEDLINE and the Cochrane Database of Systematic Reviews, as well as manual searches and gray literature searches to identify included studies.

Results

The authors were …

Pengaruh Dosis Pupuk N Dan P Terhadap Pertumbuhan Vegetatif Jarak Pagar Di Dua Tempat Berbeda, Santi Rosniawaty, Rija Sudirja

Jurnal Kultivasi

Physic nut is an alternative source of biofuel. The potential is high because it have many benefits and can not be consumed, so it will not compete with human needs. The effect of N and P fertilizer on physic nut (Jatropha curcas L.) has been studied from August 2010 until March 2011. The experiments were carried out in two different locations, in the field experiment of BPBHAT Jatinangor and farmer gardens in Plered. Soil types in Jatinangor and Plered was Inceptisol. Type of climate in Jatinangor was C while in Plered was D according to Schmidt-Ferguson (1951). Experimental design used …

Pertumbuhan Dan Hasil Tanaman Jagung (Zea Mays L.) Hibrida P-12 Yang Ditanam Pada Jarak Tanam Dan Dosis Pupuk Fosfor Yang Berbeda Pada Inseptisol Jatinangor, Agus Wahyudin, Ruminta, Nimas Nur Hafizhoh

Jurnal Kultivasi

This experiment was aims to determine the combination effect of plant spacing and phosphorus fertilizer on growth and yield of hybrid corns P-12. The experiment was conducted on March-July 2013 in inceptisol soil type in Agricultural Faculty Field Station, Padjadjaran University, Jatinangor, Sumedang, West Java. The experimental was use a Randomized Block Design with nine treatments and three replications, there is combination, plant space 75 cm x 25 cm and 200 kg/ha phosphorus fertilizer; plant space 75 cm x 25 cm and 300 kg/ha phosphorus fertilizer; plant space 75 cm x 25 cm and 400 kg/ha phosphorus fertilizer; plant space …

Ua66 Ogden College Of Science & Engineering Newsletter, Cheryl Stevens, Dean

Ogden College of Science & Engineering Publications

No abstract provided.

Species Composition And Reproductive Strategies Of Commensal Synalpheus Shrimp (Decapoda:Alpheidae) Occupying The Sponges Spheciospongia Vesparium And Spongia Sp. Of The Florida Reef Tract, Brittnee Nicole Barris

HCNSO Student Theses and Dissertations

Synalpheus shrimp species of the gambarelloides group are the only marine organisms displaying the highest level of social functioning, eusociality. Their social hierarchies are equally complex compared to the reproductive abnormalities that have been recently discovered. For instance, snapping shrimp of the genus Synalpheus were thought to be gonochoric, i.e. developing as independent sexes, until scanning electron microscopy studies revealed intersexed gonopores in several species. This project analyzed both the species composition, and accompanying reproductive structures, of Synalpheus spp. (Caridea: Alpheidae) comprised of densely aggregating communal and pair-living colonies in the Florida Keys, Florida.

Colonies of pair-living and communal Synalpheus …

Use Of Seeded Exotic Grasslands By Wintering Birds, Andrew D. George, Timothy J. O'Connell, Karen R. Hickman, David M. Lesliee Jr.

The Prairie Naturalist

Despite widespread population declines of North American grassland birds, effects of anthropogenic disturbance on wintering habitat of this guild remain poorly understood. We compared avian abundance and habitat structure in fields planted to the exotic grass Old World bluestem (Bothriochloa ischaemum; OWB) to that in native mixed-grass prairie. During winters of 2007–2008 and 2008–2009, we conducted bird and vegetation surveys in six native grass and six OWB fields in Garfield, Grant, and Alfalfa counties, Oklahoma. We recorded 24 species of wintering birds in native fields and 14 species in OWB monocultures. While vegetation structure was similar between field …